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David R Grosshans, MD/PhD

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

2004 University of Colorado, Boulder, CO, MD, Medical School
2002 University of Colorado Health Science Center, Boulder, CO, PHD, Department of Pharmacology
1995 University of Colorado, Boulder, CO, BA, Molecular, Cellular, & Developmental Biology

Postgraduate Training

7/2005-6/2009 Clinical Residency, Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Program Director, Dr. Christopher Crane
7/2004-6/2005 Clinical Internship, Medical Intership, Presbyterian Saint Lukes Hospital, Denver, CO, Dr. Grahm

Selected Publications

Peer-Reviewed Original Research Articles
1. Boehling NS, Grosshans DR, Bluett JB, Palmer MT, Song X, Amos RA, Sahoo N, Meyer JJ, Mahajan A, Woo SY. Dosimetric Comparison of Three-Dimensional Conformal Proton Radiotherapy, Intensity-Modulated Proton Therapy, and Intensity-Modulated Radiotherapy for Treatment of Pediatric Craniopharyngiomas. Int J Radiat Oncol Biol Phys. e-Pub 1/2011. PMID: 21277111.
2. Grosshans DR, Meyers CA, Allen PK, Davenport SD, Komaki R. Neurocognitive function in patients with small cell lung cancer : effect of prophylactic cranial irradiation. Cancer 112(3):589-95, 2/1/2008. PMID: 18098269.
3. Hellier JL, Grosshans DR, Coultrap SJ, Jones JP, Dobelis P, Browning MD, Staley KJ. NMDA receptor trafficking at recurrent synapses stabilizes the state of the CA3 network. J Neurophysiol 98(5):2818-26, 11/2007. e-Pub 8/29/2007. PMID: 17728388.
4. Alvestad RM, Grosshans DR, Coultrap SJ, Nakazawa T, Yamamoto T, Browning MD. Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function. J Biol Chem 278(13):11020-5, 3/28/2003. e-Pub 1/20/2003. PMID: 12536146.
5. Grosshans DR, Clayton DA, Coultrap SJ, Browning MD. Analysis of glutamate receptor surface expression in acute hippocampal slices. Sci STKE 2002(137):PL8, 6/18/2002. PMID: 12072555.
6. Clayton DA, Grosshans DR, Browning MD. Aging and surface expression of hippocampal NMDA receptors. J Biol Chem 277(17):14367-9, 4/26/2002. e-Pub 3/12/2002. PMID: 11891215.
7. Grosshans DR, Clayton DA, Coultrap SJ, Browning MD. LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci 5(1):27-33, 1/2002. PMID: 11740502.
8. Grosshans DR, Browning MD. Protein kinase C activation induces tyrosine phosphorylation of the NR2A and NR2B subunits of the NMDA receptor. J Neurochem 76(3):737-44, 2/2001. PMID: 11158244.
9. Oh JJ, Grosshans DR, Wong SG, Slamon DJ. Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells. Nucleic Acids Res 27(20):4008-17, 10/15/1999. PMCID: PMC148668.
10. Péterfy M, Gyuris T, Grosshans D, Cuaresma CC, Takács L. Cloning and characterization of cDNAs and the gene encoding the mouse platelet-activating factor acetylhydrolase Ib alpha subunit/lissencephaly-1 protein. Genomics 47(2):200-6, 1/15/1998. PMID: 9479492.
11. Chang M, McNinch J, Elias C, Manthey CL, Grosshans D, Meng T, Boone T, Andrew DP. Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes. J Biol Chem 272(40):25229-37, 10/3/1997. PMID: 9312138.
12. Wilson CA, Payton MN, Elliott GS, Buaas FW, Cajulis EE, Grosshans D, Ramos L, Reese DM, Slamon DJ, Calzone FJ. Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b. Oncogene 14(1):1-16, 1/9/1997. PMID: 9010228.

Last updated: 8/30/2011