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David Hui, M.D., M.Sc.(Biochem), M.Sc.(Clinical Rsch)

Present Title & Affiliation

Primary Appointment

Assistant Professor (tenure track), Department of Palliative Care and Rehabilitation Medicine, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Office Address

The University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd.
Unit Number: 1414
Houston, TX 77030
Room Number: FCT5.6046
Phone: 713-792-6258
Fax: 713-792-6092
Email: dhui@mdanderson.org

Education & Training

Degree-Granting Education

2010 Graduate School of Biological Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, MS, Patient Based Biological Research
2003 University of British Columbia, Vancouver, British Columbia, Canada, MD, Medicine
1999 University of British Columbia, Vancouver, British Columbia, Canada, MS, Biochemistry and Molecular Biology
1997 University of British Columbia, Vancouver, British Columbia, Canada, BS, Honors, Biochemistry and Molecular Biology

Board Certifications

2011 Clinician Investigator, Royal College of Physicians and Surgeons of Canada
2008 Medical Oncology, American Board of Internal Medicine
2008 Medical Oncology, Fellow of the Royal College of Physicians of Canada
2007 Internal Medicine, Royal College of Physicians of Canada
2007 Internal Medicine, American Board of Internal Medicine
2004 Licentiate of the Medical Council of Canada

Experience/Service

Academic Appointments

Internal Medicine Staff, Mount Saint Joseph Hospital, Vancouver, British Columbia, Canada, 2007-2008

Selected Publications

Peer-Reviewed Original Research Articles
1. Dalal S, Palla S, Hui D, Chacko R, Nguyen L, Li Z, Fadul N, Bruera E. Association between a name change from “Palliative” to “Supportive” Care and the timing of patient referrals at a comprehensive cancer center. The Oncologist 16(1):105-11, 1/2011. PMID: 21212438 detail.
2. Dev R, Hui D, Dalal S, Munsell M, Yennurajalingam S, Del Fabbro E, Bruera E. Association between serum cortisol and testosterone levels opioid therapy, and symptom distress in patients with advanced cancer. J Pain Symptom Manage 41(4):788-95, 2011. PMID: 21276699.
3. Hui D, Reddy A, Palla SL, Bruera E. Neuroleptic Prescription Pattern for Delirium in Patients with Advanced Cancer. J Palliat Med 27(2):141-7, 2011. PMID: 21805949.
4. Hui D, Parsons HA, Damani S, Fulton S, Liu J, Evans A, De La Cruz M, Bruera E. Quantity, Design and Scope of The Palliative Oncology Literature. The Oncologist 16(5):694-703, 2011. PMID: 21471275.
5. Delgado M, Hui D, De la Cruz M, Parsons H, Palmer JL, Bruera E. Spirituality, Religiosity, and Spiritual Pain in Advanced Cancer Patients. J Pain Symptom Manage 41(6):986-94, 2011. PMID: 21402459.
6. Hui D, De La Cruz M, Thorney S, Parsons H, Palmer JL, Bruera E. The Frequency and Correlates of Spiritual Distress Among Patients with Advanced Cancer Admitted to an Acute Palliative Care Unit. Am J Hosp Palliat Care 28(4):264-70, 2011. PMID: 21057143.
7. Hui D, Elsayem A, Li Z, Bruera E. Anti-Neoplastic Therapy Use in Advanced Cancer Patients Admitted to an Acute Palliative Care Unit at a Comprehensive Cancer Center: A Simultaneous Care Model. Cancer 116(8):2036-43, 2010. PMID: 20162701.
8. Del Fabbro E, Hui D, Nooruddin ZR, Dalal S, Dev R, Freer G, Palmer JL, Bruera E. Associations Among Hypogonadism, C-Reactive Protein, Symptom Burden, And Survival In Male Cancer Patients With Cachexia: A Preliminary Report. J Pain Symptom Manage 39(6):1016-24, 2010. PMID: 20457506.
9. Hui D, Elsayem A, De la Cruz M, Zhukovsky D, Berger A, Evans A, Palmer JL, Fadul N, Bruera E. Availability and Integration of Palliative Care in US Cancer Centers. JAMA 303(11):1054-61, 2010. PMID: 20233823.
10. Hui D, Bruera E. Breakthrough Pain in Cancer Patients: The Need for Evidence. Eur J Palliat Care 17(2):58-67, 2010.
11. Parsons H, De la Cruz M, Hui D, Delgado M, Zhukovsky D, El Osta B, Palla S, Bruera E. Characteristics of patients who refuse do-not-resuscitate orders upon admission to an acute palliative care unit in a comprehensive cancer center. Cancer 116(12):3061-70, 2010. PMID: 20564412.
12. Hui D, Elsayem A, Palla SL, De la Cruz M, Li Z, Bruera E. Discharge Outcomes and Survival of Patients with Advanced Cancer Admitted To An Acute Palliative Care Unit At A Comprehensive Cancer Center. J Palliat Med 13(1):49-57, 2010. PMID: 19824813.
13. Bruera E, Hui D. Integrating Supportive and Palliative Care in the Trajectory of Cancer: Goals and Models of Care. J Clin Oncol 28(25):4013-7, 2010. PMID: 20660825.
14. Hui D, Bush SH, Gallo LE, Palmer JL, Yennurajalingam S, Bruera E. Neuroleptic dose in the Management of Delirium in Patients with Advanced Cancer. J Pain Symptom Manage 39(2):186-196, 2010. PMID: 20152585.
15. De la Cruz M, Hui D, Parsons H, Palmer JL, Bruera E. Placebo and Nocebo Effects in Randomized Double Blind Clinical Trials of Agents for the Treatment of Fatigue in Advanced Cancer Patients. Cancer 116(3):766-74, 2010. PMID: 19918921.
16. Hui D, Donaldson J, Hoskins P, Klasa R, Savage K, Shenkier T, Gascoyne R, Connors J, Sehn L. Prognostic Implications Of Extranodal Involvement In Patients With Diffuse Large B-Cell Lymphoma Treated With Rituximab And Cyclophosphamide, Doxorubicin, Vincristine, And Prednisone. Leukemia Lymphoma 51(9):1658-67, 2010. PMID: 20795790.
17. Reddy S, Hui D, De la Cruz M, Bruera E. The Effect of Oral Methadone On The QTc Interval In Advanced Cancer Patients: A Prospective Pilot Study. J Palliat Med 13(1):33-8, 2010.
18. Hui D, Parsons H, Nguyen L, Palla S, Yennurajalingam S, Kurzrock R, Bruera E. Timing of Palliative Care Referral and Symptom Burden in Phase I Cancer Patients: A Retrospective Cohort Study. Cancer 116(18):4402-9, 2010. PMID: 20564164.
19. Hui D, Con A, Christie G, Hawley P. Goals of Care and End-of-Life Decision Making for Hospitalized Patients at a Canadian Tertiary Care Cancer Centre. J Pain Symptom Manage 38(6):871-81, 2009. PMID: 19811887.
20. Elsayem A, Mori M, Parsons H, Munsell M, Hui D, Delgado M, Fadul N, Bruera E. Predictors of Inpatient Mortality in an Acute Palliative Care Unit at a Comprehensive Cancer Center. Support Care Cancer 18(1):67-76, 2009. PMID: 19350282.
21. Hui D, Lam W, Toze C, Delorme M, Noble M, Klimo P, Sutherland J, Gill K, Connors J, Sehn L. Alemtuzumab in Clinical Practice: A British Columbia Experience. Leukemia and Lymphoma 49(2):218-226, 2008. PMID: 18231907.
22. Spratlin J, Hui D, Hanson J, Butts C, Au HJ. Community Compliance With Carcinoembryonic Antigen: Follow-Up Of Patients With Colorectal Cancer. Clin Colorectal Cancer 7(2):118-25, 2008. PMID: 18501071.
23. Czaykowski P, Hui D. Chemotherapy in Small Bowel Adenocarcinoma: 10 Year Experience from the BC Cancer Agency. J Clin Oncol 19(2):143-149, 2007. PMID: 17355111.
24. Al Kaptan M, Hui D, Frantz C, Dabbagh L, Reiman T, Lai R. Enteropathy Associated T-cell Lymphoma with an Unusually Late Relapse – A Case Report. J Clin Oncol 60(1):108, 2007. PMID: 17213361.
25. Lai R, Lefresne S, Franko B, Hui D, Hanson J, Mirza I, Mansoor A, Amin H, Ma Y. Immunoglobulin VH Somatic Hypermutation in Mantle Cell Lymphoma: Mutated Genotype Correlates with Better Clinical Outcome. Mod Pathol 19(11):1498-505, 2006. PMID: 16980950.
26. Hui D, Satkunam N, Al Kaptan M, Reiman T, Lai R. Pathway-Specific Apoptotic Gene Expression Profiling in Chronic Lymphocytic Leukemia and Follicular Lymphoma. Mod Pathol 19(9):1192-202, 2006. PMID: 16763612.
27. Hui D, Reiman T, Dabbagh L, Hanson J, Amin HM, Lai R. ZAP–70 Expression Correlates with Unmutated IgVH Genotype and Worse Clinical Outcome in Mantle Cell Lymphoma. Leukemia 20(10):1905-8, 2006. PMID: 16932342.
28. Hui D, Reiman T, Hanson J, Lanford R, Wong W, Belch A, Lai R. Immunohistochemical Detection of CDC2 is Useful in Predicting Survival in Patients with Mantle Cell Lymphoma. Mod Pathol 18(9):1223-31, 2005.
29. Agranovich A, Czaykowski P, Hui D, Pickles T, Kwan W. Radiotherapy for Muscle-Invasive Urinary Bladder Cancer in Elderly Patients. Can J Urol 10(6):2056-61, 2003.
30. Hui D, Ling V. A Combinatorial Approach toward Analyzing Functional Elements of the Escherichia coli Hemolysin Signal Sequence. Biochemistry 41(17):5333-9, 2002.
31. Zhang F, Zhang W, Liu L, Fisher CL, Hui D, Childs S, Dorovini-Zis K, Ling V. Characterization of ABCB9, an ATP Binding Cassette Protein associated with Lysosomes. J Biol Chem 275(30):23287-94, 7/2000. PMID: 10748049.
32. Hui D, Morden C, Zhang F, Ling V. Combinatorial Analysis of the Structural Requirements of the Escherichia coli Hemolysin Signal Sequence. J Biol Chem 275(4):2713-20, 1/2000. PMID: 10644734.
33. Zhang F, Hogue D, Liu L, Fisher CL, Hui D, Childs S, Ling V. M-ABC2, a New Human Mitochondrial ATP-Binding Cassette Membrane Protein. FEBS Letters 478(1-2):89-94, 2000.
34. Childs S, Yeh RL, Hui D, Ling V. Taxol Resistance mediated by Transfection of the Liver-specific Sister Gene of P-glycoprotein. Cancer Res 58(18):4160-7, 9/1998. PMID: 9751629.

Grant & Contract Support

Title: Novel Physiologic Prognostic Factors in Patients with Advanced Cancer
Funding Source: MD Anderson Cancer Center Institutional Research Grant
Role: Principal Investigator
Duration: 4/1/2011
 
Title: Start Up Funds
Funding Source: MD Anderson Cancer Center
Role: Principal Investigator
Duration: 3/1/2011 - present

Last updated: 2/12/2013