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David E. Ost, M.D., M.P.H., F.A.C.P.

Department of Pulmonary Medicine, Division of Internal Medicine

Present Title & Affiliation

Primary Appointment

Professor, Department of Pulmonary Medicine, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Research Interests

My long-term goal is to understand the factors that contribute to pulmonary morbidity and mortality in cancer patients in order to develop more cost-effective treatments and interventions. My particular area of focus is interventional pulmonology. Areas of interest include diagnosis and staging of lung cancer using endobronchial ultrasound, comparative effectiveness of bronchial stenting, impact of bronchoscopic interventions on quality adjusted survival, and impact of indwelling pleural catheters on quality adjusted survival and health care resource utilization

Education & Training

Postgraduate Training

1993-1996	Clinical Fellowship, Pulmonary & Critical Care, Northwestern University Hospital, Chicago, Illinois
1991-1993	Clinical Residency, Resident in Internal Medicine, Northwestern University Hospital, Chicago, Illinois
1990-1991	Clinical Internship, Intern in Medicine, Northwestern University Hospital, Chicago, Illinois

Board Certifications

2017	American Association for Bronchology and Interventional Pulmonology, Diplomate Interventional Pulmonology
1997	American Board of Internal Medicine, Subspecialty Critical Care
1996	American Board of Internal Medicine, Subspecialty Pulmonary

Experience & Service

Academic Appointments

Associate Professor, Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2009 - 2014

Associate Professor, New York University School of Medicine, New York, NY, 2004 - 2008

Assistant Professor, New York University School of Medicine, New York, NY, 2001 - 2004

Instructor, New York University School of Medicine, New York, NY, 1996 - 2001

Other Appointments/Responsibilities

Summer Fellowship in Molecular Biology, National Institutes of Health, Bethesda, MD, 1987

Summer Fellowship in Molecular Biology, National Institute of Health, Bethesda, MD, 1986

Institutional Committee Activities

Member, Context Engine (formerly D3Code), 2020 - Present

Member, Retreat Working Group: Protocol Amendment Review and Approval, 2017

Chair, Epic for Clinical Research Committee Meeting, 2016 - Present

Chair, Division of Internal Medicine Research Committee, 2015 - 2017

Member, Promotion and Tenure Committee, 2015 - 2016

Member, Conflict of Interest Committee, 2015 - 2017

Member, Clinical Research Advisory Committee (CRAC), 2012 - Present

Member, Faculty Senate, The University of Texas MD Anderson Cancer Center, 2010 - 2016

Vice Chair, Division of Medicine Research Committee, The University of Texas MD Anderson Cancer Center, 2009 - 2015

Bellevue Hospital, Ambulatory Surgery Committee, 2005 - 2008

New York University Medical Center, Quality Improvement Committee, 2005 - 2008

North Shore University Hospital, Quality Improvement Committee, 1999 - 2003

North Shore University Hospital, Institutional Review Board Member, 1998 - 2002

Professional Memberships

American Board of Internal Medicine

2014 - Present

Harris County Medical Society

2009 - Present

American College of Chest Physicians

2008 - Present

American Association of Bronchoscopy and Interventional Pulmonology

2001 - 2009

American Thoracic Society

2000 - Present

Selected Publications

Peer-Reviewed Articles

Ost DE, Maldonado F, Shafrin J, Kim J, Marin MA, Amos TB, Hertz DS, Kalsekar I, Vachani A. Economic Value of Bronchoscopy Technologies that Improves Sensitivity for Malignancy for Peripheral Pulmonary Lesions. Ann Am Thorac Soc 21(12):1759-1769, 2024. e-Pub 2024. PMID: 39178335.
Grosu H, Cabrera M, Madrigal DL, Sainz Zuniga PV, Ost D. Risk of Pleural Recurrence in Early-Stage Non-small Cell Lung Cancer in Patients Treated With Surgery vs Stereotactic Ablative Radiotherapy. Cureus 16(11):e73544, 2024. PMID: 39669832.
Bashour SI, Khan A, Song J, Chintalapani G, Kleinszig G, Sabath BF, Lin J, Grosu HB, Jimenez CA, Eapen GA, Ost DE, Sarkiss M, Casal RF. Improving Shape-Sensing Robotic-Assisted Bronchoscopy Outcomes with Mobile Cone-Beam Computed Tomography Guidance. Diagnostics (Basel) 14(17), 2024. e-Pub 2024. PMID: 39272739.
Sainz PV, Horiana BG, Samira S, Ost DE. Improving Cancer Probability Estimation in Non-Diagnostic Bronchoscopies: A meta-analysis. Chest 166(6):1557-1572, 2024. e-Pub 2024. PMID: 39059579.
Shojaee S, Pannu J, Yarmus L, Fantin A, MacRosty C, Bassett R Jr, Debiane L, DePew ZS, Faiz SA, Jimenez CA, Avasarala SK, Vakil E, DeMaio A, Bashoura L, Keshava K, Ferguson T, Adachi R, Eapen GA, Ost DE, Bashour S, Khan A, Shannon V, Sheshadri A, Casal RF, Evans SE, Pew K, Castaldo N, Balachandran DD, Patruno V, Lentz R, Pai C, Maldonado F, Roller L, Ma J, Zaveri J, Los J, Vaquero L, Ordonez E, Yermakhanova G, Akulian J, Burks C, Almario RR, Sauve M, Pettee J, Noor LZ, Arain MH, Grosu HB. GRAvity- versus Wall suction-drIven large volume Thoracentesis: a rAndomized controlled Study (GRAWITAS study). Chest 166(6):1573-1582, 2024. e-Pub 2024. PMID: 39029784.
Ost DE, Goldblatt C, Jung M, Weiss M, Xu S, Taneja A, Erdal E. The Clinical and Economic Implications of Different Treatment Pathways for Patients With Rapidly Recurrent Malignant Pleural Effusion. Chest 166(4):867-881, 2024. e-Pub 2024. PMID: 38838953.
Steinfort, DP, Kothari, G, Wallace, N, Hardcastle, N, Rangamuwa, K, Dieleman, EM, Lee, PP, Li, P, Simpson, JA, Yo, S, Bashirdazeh, F, Nguyen, P, Jennings, BR, Fielding, D, Crombag, L, Irving, LB, Yasufuku, K, Annema, J, Ost, D, Siva, S. Systematic endoscopic staging of mediastinum to guide radiotherapy planning in patients with locally advanced non-small-cell lung cancer (SEISMIC). The Lancet Respiratory Medicine 12(6):467-475, 2024. e-Pub 2024. PMID: 38490228.
Chang, CH, Ost, D, Jimenez, C, Saltijeral, SN, Eapen, GA, Casal, RF, Sabath, BF, Lin, J, Cerrillos, E, Nevarez Tinoco, T, Grosu, HB. Outcomes of Pleural Space Infections in Patients with Indwelling Pleural Catheters for Active Malignancies. Journal of Bronchology and Interventional Pulmonology 31(2):155-159, 2024. e-Pub 2024. PMID: 37982602.
Sheshadri A, Rajaram R, Baugh A, Castro M, Correa A, Soto F, Daniel-MacDougall CR, Li L, Evans SE, Dickey BF, Vaporciyan AA, Ost DE. Association of Pre-operative Lung Function with Complications after Lobectomy Using Race-Neutral and Race-Specific Normative Equations. Ann Am Thorac Soc 21(1):38-46, 2024. e-Pub 2023. PMID: 37796618.
Ost DE, Feller-Kopman DJ, Gonzalez AV, Grosu HB, Herth F, Mazzone P, Park JES, Porcel JM, Shojaee S, Tsiligianni I, Vachani A, Bernstein J, Branson R, Flume PA, Akdis CA, Kolb M, Portela EB, Smyth A. Reporting Standards for Diagnostic Testing: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals. J Bronchology Interv Pulmonol 30(3):207-222, 2023. e-Pub 2023. PMID: 37070780.
Wahidi MM, Lamb CR, Kovitz K, Keyes C, Bechara R, Giovacchini CX, French K, Shojaee S, Musani A, Eapen G, Ost DE. Interventional Pulmonology Productivity, Compensation, and Practice Benchmarks: The AABIP 2022 Report. J Bronchology Interv Pulmonol 30(2):129-134, 2023. e-Pub 2023. PMID: 36825802.
Tellez Garcia E, Ost D, Grosu HB. The Impact of Anticoagulation on Indwelling Pleural Catheter Removal due to Pleurodesis in Patients with Malignant Pleural Effusion. Respiration 102(4):1-8, 2023. e-Pub 2023. PMID: 36720213.
Salahuddin M, Ost D, Hwang H, Jimenez C, Saltijeral S, Eapen G, Casal R, Sabath B, Lin J, Cerrillos E, Nevárez Tinoco T, Grosu H. Clinical Risk Factors for Death in Patients With Empyema and Active Malignancy. Cureus 15(4):e37545, 2023. e-Pub 2023. PMID: 37197128.
Steiling K, Kathuria H, Echieh CP, Ost DE, Rivera MP, Begnaud A, Celedón JC, Charlot M, Dietrick F, Duma N, Fong KM, Ford JG, Gould MK, Holguin F, Pérez-Stable EJ, Tanner NT, Thomson CC, Wiener RS, Wisnivesky J. Research Priorities for Interventions to Address Health Disparities in Lung Nodule Management: An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med 207(6):e31-e46, 2023. e-Pub 2023. PMID: 36920066.
Alkhunaizi M, Patel B, Bueno L, Bhan N, Ahmed T, Arain MH, Saliba R, Rondon G, Dickey BF, Bashoura L, Ost DE, Li L, Wang S, Shpall E, Champlin RE, Mehta R, Popat UR, Hosing C, Alousi AM, Sheshadri A. Risk Factors for Bronchiolitis Obliterans Syndrome after Initial Detection of Pulmonary Impairment after Hematopoietic Cell Transplantation. Transplant Cell Ther 29(3):204 e1-e7, 2023. e-Pub 2023. PMID: 36503180.
Chang CH, Ost DE, Jimenez CA, Saltieral SN, Eapen GA, Casal RF, et al. Outcomes of Pleural Space Infections in Patients With Indwelling Pleural Catheters for Active Malignancies. J Bronchology Interv Pulmol, 2023. e-Pub 2023.
Martinez-Zayas G, Molina S, Ost DE. Sensitivity and complications of thoracentesis and thoracoscopy: a meta-analysis. Eur Respir Rev 31(166), 2022. e-Pub 2022. PMID: 36543349.
Salahuddin M, Sarkiss M, Sagar AS, Vlahos I, Chang CH, Shah A, Sabath BF, Lin J, Song J, Moon T, Norman PH, Eapen GA, Grosu HB, Ost DE, Jimenez CA, Chintalapani G, Casal RF. "Ventilatory Strategy to Prevent Atelectasis During Bronchoscopy Under General Anesthesia: A Multicenter Randomized Controlled Trial" (VESPA Trial). Chest 162(6):1393-1401, 2022. e-Pub 2022. PMID: 35803302.
Gonzalez AV, Ost DE, Shojaee S. Diagnostic Accuracy of Bronchoscopy Procedures: Definitions, Pearls, and Pitfalls. J Bronchology Interv Pulmonol 29(4):290-299, 2022. e-Pub 2022. PMID: 36066281.
Steinfort DP, Siva S, Rangamuwa K, Lee P, Fielding D, Nguyen P, Jennings BR, Yo S, Hardcastle N, Kothari G, Crombag L, Annema J, Yasufuku K, Ost DE, Irving LB. Systematic endoscopic staging of mediastinum to determine impact on radiotherapy for locally advanced lung cancer (SEISMIC): protocol for a prospective single arm multicentre interventional study. BMC Pulm Med 22(1):364, 2022. e-Pub 2022. PMID: 36153502.
Grosu HB, Kern R, Maldonado F, Casal R, Andersen CR, Li L, Eapen G, Ost D, Jimenez C, Frangopoulos F, Sabath B, Vakil E, Schwalk A, Marcoux M, Sagar AE, Nasim F, Lin J, Salahudin M, Arain HM, Noor L, Montanez D, Stewart J, Mullon J, Michael M, Porfyridis I. Predicting malignant pleural effusion during diagnostic pleuroscopy with biopsy: A prospective multicentre study. Respirology 27(5):350-356, 2022. e-Pub 2022. PMID: 35178828.
Sheshadri A, Makhnoon S, Alousi AM, Bashoura L, Andrade R, Miller CJ, Stolar KR, Arain MH, Noor L, Balagani A, Jain A, Blanco D, Ortiz A, Taylor MS, Stenzler A, Mehta R, Popat UR, Hosing C, Ost DE, Champlin RE, Dickey BF, Peterson SK. Home-Based Spirometry Telemonitoring After Allogeneic Hematopoietic Cell Transplantation: Mixed Methods Evaluation of Acceptability and Usability. JMIR Form Res 6(2):e29393, 2022. e-Pub 2022. PMID: 35129455.
Reisenauer J, Simoff MJ, Pritchett MA, Ost DE, Majid A, Keyes C, Casal RF, Parikh MS, Diaz-Mendoza J, Fernandez-Bussy S, Folch EE. Ion: technology and techniques for shape-sensing robotic-assisted bronchoscopy. Ann Thorac Surg. 2022; 113(1):308-15, 2022. e-Pub 2021. PMID: 34370981.
Ost DE. Interpretation and Application of the Likelihood Ratio to Clinical Practice in Thoracic Oncology. J Bronchology Interv Pulmonol 29(1):62-70, 2022. e-Pub 2022. PMID: 34162800.
Vakil E, Jackson N, Sainz-Zuñega PV, Molina S, Martinez-Zayas G, Cantor SB, Grosu HB, Casal RF, Ost DE. Optimizing diagnostic and staging pathways for suspected lung cancer: a decision analysis. Chest 2021; 160(6):2304-23, 2021. e-Pub 2021. PMID: 34256049.
Sainz Zuniga PV, Ost DE. Impact of Delays in Lung Cancer Treatment on Survival. Chest 2021; 160(5):1934-58, 2021. e-Pub 2021. PMID: 34425080.
Simoff MJ, Pritchett MA, Reisenauer JS, Ost DE, Majid A, Keyes C, Casal RF, Parikh MS, Diaz-Mendoza J, Fernandez-Bussy S, Folch EE. Shape-sensing robotic-assisted bronchoscopy for pulmonary nodules: initial multicenter experience using the Ion™ Endoluminal System. BMC Pulm Med 21(1):322, 2021. e-Pub 2021. PMID: 34656103.
Molina S, Martinez-Zayas G, Sainz PV, Leung CH, Li L, Grosu HB, Adachi R, Ost DE. BLESS models: Improving Survival Prediction in Patients with Malignant Pleural Effusion and Metastasis. Chest 160(3):1075-1094, 2021. e-Pub 2021. PMID: 33852918.
Martinez-Zayas G, Almeida FA, Yarmus L, Steinfort D, Lazarus DR, Simoff MJ, Saettele T, Murgu S, Dammad T, Duong DK, Mudambi L, Filner JJ, Molina S, Aravena C, Thiboutot J, Bonney A, Rueda AM, Debiane LG, Hogarth DK, Bedi H, Deffebach M, Sagar AS, Cicenia J, Yu DH, Cohen A, Frye L, Grosu HB, Gildea T, Feller-Kopman D, Casal RF, Machuzak M, Arain MH, Sethi S, Eapen GA, Lam L, Jimenez CA, Ribeiro M, Noor LZ, Mehta A, Song J, Choi H, Ma J, Li L, Ost DE. Predicting Lymph Node Metastasis in Non-Small Cell Lung Cancer: Prospective External and Temporal Validation of the HAL and HOMER Models. Chest 160(3):1108-1120, 2021. e-Pub 2021. PMID: 33932466.
Wilshire CL, Chang SC, Gilbert CR, Akulian JA, AlSarraj MK, Asciak R, Bevill BT, Davidson KR, Delgado A, Grosu HB, Herth FJ, Lee HJ, Lewis JE, Maldonado F, Ost DE, Pastis NJ, Rahman NM, Reddy CB, Roller LJ, Sanchez TM, Shojaee S, Steer H, Thiboutot J, Wahidi MM, Wright AN, Yarmus LB, Gorden JA. Temporal trends in tunneled pleural catheter utilization in patients with malignancy: A multicenter review. Chest 2021; 159(6):2483-7, 2021. e-Pub 2020. PMID: 33307064.
Sainz Zúñiga PV, Martinez-Zayas G, Molina S, Grosu HB, Arain MH, Ost DE. Is Biopsy of Contralateral Hilar N3 Lymph Nodes With Negative PET-CT Scan Findings Necessary When Performing Endobronchial Ultrasound Staging?. Chest 2021; 159(4):1642-51, 2021. e-Pub 2021. PMID: 33393471.
Wilshire CL, Chang SC, Gilbert CR, Akulian JA, AlSarraj MK, Asciak R, Bevill BT, Davidson KR, Delgado A, Grosu HB, Herth FJF, Lee HJ, Lewis JE, Maldonado F, Ost DE, Pastis NJ, Rahman NM, Reddy CB, Roller LJ, Sanchez TM, Shojaee S, Steer H, Thiboutot J, Wahidi MM, Wright AN, Yarmus LB, Gorden JA. Association between Tunneled Pleural Catheter Use and Infection in Patients Immunosuppressed from Antineoplastic Therapy. A Multicenter Study. Ann Am Thorac Soc 18(4):606-612, 2021. e-Pub 2021. PMID: 33026887.
Zhang Y, Simoff MJ, Ost D, Wagner OJ, Lavin J, Nauman B, Hsieh MC, Wu XC, Pettiford B, Shi L. Understanding the patient journey to diagnosis of lung cancer. BMC Cancer 21(1):402, 2021. e-Pub 2021. PMID: 33853552.
Schwalk AJ, Ost DE, Saltijeral SN, De La Garza H, Casal RF, Jimenez CA, Eapen GA, Lewis J, Rinsurongkawong W, Rinsurongkawong V, Lee J, Elamin Y, Zhang J, Roth JA, Swisher S, Heymach JV, Grosu HB. Risk Factors for and Time to Recurrence of Symptomatic Malignant Pleural Effusion in Patients with Metastatic Non-Small Cell Lung Cancer with EGFR or ALK Mutations. Chest 159(3):1256-1264, 2021. e-Pub 2021. PMID: 33217413.
Chiu YW, Kao YH, Simoff MJ, Ost DE, Wagner O, Lavin J, Culbertson RA, Smith DG. Costs of Biopsy and Complications in Patients with Lung Cancer. Clinicoecon Outcomes Res 13:191-200, 2021. e-Pub 2021. PMID: 33762834.
Sagar AS, Sabath BF, Eapen GA, Song J, Marcoux M, Sarkiss M, Arain MH, Grosu HB, Ost DE, Jimenez CA, Casal RF. Incidence and Location of Atelectasis Developed During Bronchoscopy Under General Anesthesia: The I-LOCATE Trial. Chest 158(6):2658-2666, 2020. e-Pub 2020. PMID: 32561439.
Datar S, Cabanillas M, Dadu R, Ost D, Grosu HB. Pulmonary cavitation in patients with thyroid cancer receiving antiangiogenic agents. BMC Cancer 20(1):1181, 2020. e-Pub 2020. PMID: 33267782.
Zhao H, Xu Y, Huo J, Burks AC, Ost DE, Shih YT. Updated Analysis of Complication Rates Associated With Invasive Diagnostic Procedures After Lung Cancer Screening. JAMA Netw Open 3(12):e2029874, 2020. e-Pub 2020. PMID: 33326023.
Gilbert CR, Wahidi MM, Light RW, Rivera MP, Sterman DH, Thomas R, Shojaee S, Shoham S, Psallidas I, Ost DE, Molena D, Maskell N, Maldonado F, Liberman M, Lee YCG, Lee H, Herth FJF, Grosu H, Gorden JA, Fysh ETH, Corcoran JP, Argento AC, Akulian JA, Rahman NM, Yarmus LB, Outcomes Group IP. Management of Indwelling Tunneled Pleural Catheters: A Modified Delphi Consensus Statement. Chest 158(5):2221-2228, 2020. e-Pub 2020. PMID: 32561437.
Sheshadri A, Alousi A, Bashoura L, Stolar K, Baghaie S, Arain MH, Noor L, Balagani A, Jain A, Blanco D, Ortiz A, Peterson SK, Langhals R, Taylor M, Stenzler A, Mehta RS, Popat UR, Hosing C, Rondon G, Shen F, Li L, Cheng GS, Ost DE, Champlin RE, Dickey BF. Feasibility and Reliability of Home-based Spirometry Telemonitoring in Allogeneic Hematopoietic Cell Transplant Recipients. Ann Am Thorac Soc 17(10):1329-1333, 2020. e-Pub 2020. PMID: 32614241.
Vial MR, Nasim F, La Garza H, Ost DE, Casal RF, Eapen GA, Jimenez C, Grosu HB. Endobronchial ultrasound- guided transbronchial needle aspiration for mediastinal lymph node staging in patients with typical pulmonary carcinoids. Lung Cancer 147:198-203, 2020. e-Pub 2020. PMID: 32736278.
Wahidi MM, Shojaee S, Lamb CR, Ost D, Maldonado F, Eapen G, Caroff DA, Stevens MP, Ouellette DR, Lilly C, Gardner DD, Glisinski K, Pennington K, Alalawi R. The Use of Bronchoscopy During the Coronavirus Disease 2019 Pandemic: CHEST/AABIP Guideline and Expert Panel Report. Chest 158(3):1268-1281, 2020. e-Pub 2020. PMID: 32361152.
Ost DE, Niu J, Zhao H, Grosu HB, Giordano SH. Quality Gaps and Comparative Effectiveness in Lung Cancer Staging and Diagnosis. Chest 157(5):1322-1345, 2020. e-Pub 2020. PMID: 31610159.
Goldblatt DL, Flores JR, Valverde Ha G, Jaramillo AM, Tkachman S, Kirkpatrick CT, Wali S, Hernandez B, Ost DE, Scott BL, Chen J, Evans SE, Tuvim MJ, Dickey BF. Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice. Br J Pharmacol 177(10):2256-2273, 2020. e-Pub 2020. PMID: 31968123.
Leisman DE, Harhay MO, Lederer DJ, Abramson M, Adjei AA, Bakker J, Ballas ZK, Barreiro E, Bell SC, Bellomo R, Bernstein JA, Branson RD, Brusasco V, Chalmers JD, Chokroverty S, Citerio G, Collop NA, Cooke CR, Crapo JD, Donaldson G, Fitzgerald DA, Grainger E, Hale L, Herth FJ, Kochanek PM, Marks G, Moorman JR, Ost DE, Schatz M, Sheikh A, Smyth AR, Stewart I, Stewart PW, Swenson ER, Szymusiak R, Teboul JL, Vincent JL, Wedzicha JA, Maslove DM. Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals. Crit Care Med 48(5):623-633, 2020. e-Pub 2020. PMID: 32141923.
Sainz Zuñiga PV, Vakil E, Molina S, Bassett RL, Ost DE. Sensitivity of Radial Endobronchial Ultrasound-Guided Bronchoscopy for Lung Cancer in Patients With Peripheral Pulmonary Lesions: An Updated Meta-analysis. Chest 157(4):994-1011, 2020. e-Pub 2020. PMID: 31738928.
Grosu HB, Manzanera A, Shivakumar S, Sun S, Noguras Gonzalez G, Ost DE. Survival Disparities Following Surgery Among Patients with Different Histological Types of Non-small Cell Lung Cancer. Lung Cancer 140:55-58, 2020. e-Pub 2020. PMID: 31865279.
Bailey M, Eapen G, Ost D, Casal RF, Jimenez C, Datar S, Molina S, Bashoura L, Faiz SA, Balachandran DD, Shannon VR, Sheshadri A, Grosu HB. Routine Microbiologic Studies of Pleural Fluid Specimens in Cancer Patients. Am J Med 133(2):240-244, 2020. e-Pub 2020. PMID: 31401163.
Sagar AES, Landaeta MF, Adrianza AM, Aldana GL, Pozo L, Armas-Villalba A, Toquica CC, Larson AJ, Vial MR, Grosu HB, Ost DE, Eapen GA, Sheshadri A, Morice RC, Shannon VR, Bashoura L, Balachandran DD, Almeida FA, Uzbeck MH, Casal RF, Faiz SA, Jimenez CA. Complications following symptom limited thoracentesis using suction. Eur Respir J 56(5), 2020. e-Pub 2020. PMID: 32499336.
Grosu HB, Lu W, Ost DE, Vial MR, Hernandez M, Ghosh N, Noor L, Hasan AM, Bashoura L, Faiz S, Balachandran D, Casal R, Eapen G, Shannon V, Sheshadri A, Tang X, Rahman N, Wistuba II. Pleural Fluid Cytokine Levels at Baseline and Over Time are Associated With Time to IPC Removal: An Exploratory Study. J Bronchology Interv Pulmonol 27(1):4-13, 2020. e-Pub 2020. PMID: 31373905.
Martinez-Zayas G, Almeida FA, Simoff MJ, Yarmus L, Molina S, Young B, Feller-Kopman D, Sagar AS, Gildea T, Debiane LG, Grosu HB, Casal RF, Arain MH, Eapen GA, Jimenez CA, Noor LZ, Baghaie S, Song J, Li L, Ost DE. A Prediction Model to Help with Oncologic Mediastinal Evaluation for Radiation: HOMER. Am J Respir Crit Care Med 201(2):212-223, 2020. e-Pub 2020. PMID: 31574238.
Sheshadri, A, Godoy, M, Erasmus, JJ, Gruschkus, SK, Hasan, AM, Evans, S, Barreda-Garcia, J, Chemaly, RF, Dickey, BF, Ost, D. Progression of the Radiologic Severity Index is associated with increased mortality and healthcare resource utilisation in acute leukaemia patients with pneumonia. BMJ Open Respiratory Research 6(1), 2019. e-Pub 2019. PMID: 31921429.
Grosu HB, Arriola A, Stewart J, Ma J, Bassett R, Hernandez M, Ost D, Roy-Chowdhuri S. PD-L1 Detection in Histology Specimens and Matched Pleural Fluid Cell Blocks of Patients with NSCLC. Respirology 24(12):1198-1203, 2019. e-Pub 2019. PMID: 31209954.
Sagar AS, Eapen GA, Casal RF, Ost D, Sarkiss M, Grosu HB. Safety of Pleuroscopy Performed in Negative Pressure Bronchoscopy Rooms. J Bronchology Interv Pulmonol 26(4):250-253, 2019. e-Pub 2019. PMID: 30543551.
Debiane, LG, Reitzel, R, Rosenblatt, J, Gagea Iurascu, M, Chavez, MA, Adachi, R, Grosu, HB, Sheshadri, A, Hill, LR, Raad, II, Ost, D. A Design-Based Stereologic Method to Quantify the Tissue Changes Associated with a Novel Drug-Eluting Tracheobronchial Stent. Respiration 98(1):60-69, 2019. e-Pub 2019. PMID: 30799409.
Herman DD, Thomson CC, Brosnhan S, Patel R, Trosini-Desert V, Bilaceroglu S, Poston JT, Liberman M, Shah PL, Ost DE, Chatterjee R, Michaud GC. Risk of Bleeding in Patients Undergoing Pulmonary Procedures on Antiplatelet or Anticoagulants: A Systematic Review. Respir Med(153):76-84, 2019. e-Pub 2019.
Casal RF, Sepesi B, Sagar AS, Tschirren J, Chen M, Li L, Sunny J, Williams J, Grosu HB, Eapen GA, Jimenez CA, Ost DE. Centrally Located Lung Cancer and Risk of Occult Nodal Disease: An Objective Evaluation of Multiple Definitions of Tumour Centrality with Dedicated Imaging Software. Eur Respir J 53:5, 2019. e-Pub 2019.
Grosu, HB, Vial, MR, Hernandez, M, Li, L, Casal, RF, Eapen, GA, Ost, D. Secondary spontaneous pneumothorax in cancer patients. Journal of Thoracic Disease 11(4):1495-1505, 2019. e-Pub 2019. PMID: 31179092.
Debiane L, Reitzel R, Rosenblatt J, Gagea M, Chavez MA, Adachi R, Grosu HB, Sheshadri A, Hill LR, Raad I, Ost DE. A Design-Based Stereologic Method to Quantify the Tissue Changes Associated with a Novel Drug-Eluting Tracheobronchial Stent. Respiration(98 (1)):60-69. e-Pub 2019.
Sheshadri, A, Karimipour, M, Vakil, E, Bashoura, L, Godoy, M, Arain, MH, Evans, S, Dickey, BF, Ost, D, Chemaly, RF, Faiz, S. Refinement of estimates of mortality risk using the Radiologic Severity Index in hematologic malignancy patients with respiratory syncytial virus infection. Transplant Infectious Disease 21(4), 2019. e-Pub 2019. PMID: 31081570.
Casal, RF, Sepesi, B, Sagar, AS, Tschirren, J, Chen, M, Li, L, Sunny, J, Williams, J, Grosu, HB, Eapen, GA, Jimenez, C, Ost, D. Centrally located lung cancer and risk of occult nodal disease. The European respiratory journal 53(5), 2019. e-Pub 2019. PMID: 30819811.
Lederer DJ, Bell SC, Branson RD, Chalmers JD, Marshall R, Maslove DM, Ost DE, Punjabi NM, Schatz M, Smyth AR, Stewart PW, Suissa S, Adjei AA, Akdis CA, É A, Bakker J, Ballas ZK, Bardin PG, Barreiro E, Bellomo R, Bernstein JA, Brusasco V, Buchman TG, Chokroverty S, Collop NA, Crapo JD, Fitzgerald DA, Hale L, Hart N, Herth FJ, Iwashyna TJ, Jenkins G, Kolb M, Marks GB, Mazzone P, Moorman JR, Murphy TM, Noah TL, Reynolds P, Riemann D, Russell RE, Sheikh A, Sotgiu G, Swenson ER, Szczesniak R, Szymusiak R, Teboul JL, Vincent JL. Control of Confounding and Reporting of Results in Causal Inference Studies. Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals. Ann Am Thorac Soc 16(1):22-28, 2019. e-Pub 2019. PMID: 30230362.
Mahajan AK, Ost DE, Cole BF, Kinsey CM. Applications of Noninferiority Trials in Interventional Pulmonology. J Bronchology Interv Pulmonol 26(1):6-9, 2019. e-Pub 2019. PMID: 30562280.
Grosu HB, Molina S, Casal R, Song J, Li L, Diaz-Mendoza J, Reddy C, Yarmus L, Schiavo D, Simoff M, Johnstun J, Raid AA, Feller-Kopman D, Lee H, Sahetya S, Foley F, Maldonado F, Tian X, Noor L, Miller R, Mudambi L, Saettele T, Vial-Rodriguez M, Eapen GA, Ost DE. Risk Factors for Pleural Effusion Recurrence in Patients with Malignancy. Respirology 23(1):76-82, 2019. e-Pub 2019. PMID: 29966171.
Ong P, Grosu HB, Debiane L, Casal RF, Eapen GA, Jimenez CA, Noor L, Ost DE. Long-term Quality-adjusted Survival Following Therapeutic Bronchoscopy for Malignant Central Airway Obstruction. Thorax 74(2):141-156, 2019. e-Pub 2019. PMID: 30254139.
Mahajan AK, Ost DE, Cole BF, Kinsey CM. Applications of Noninferiority Trials in Interventional Pulmonology. J Bronchology Interv Pulmonol 26(1):6-9, 2019. e-Pub 2019.
Grosu HB, Vial MR, Hernandez M, Li L, Casal RF, Eapen GA, Ost DE. Secondary Spontaneous Pneumothorax in Cancer Patients. Journal of Thoracic Disease 11(4):1495-1505, 2019. e-Pub 2019.
Sheshadri A, Karimipour M, Vakil E, Bashoura L, Godoy M, Arain MH, Evans SE, Dickey BF, Ost DE, Chemaly RF, Faiz SA. Refinement of Estimates of Mortality Risk Using the Radiologic Severity Index in Hematologic Malignancy Patients with Respiratory Syncytial Virus Infection. Transplant Infectious Disease: An Official Journal of the Transplantation Society:e13105, 2019. e-Pub 2019.
Sabath B, Muhammad HA, Balagani A, Ost DE, Vakil E, Ahmed T, Vial MR, Grosu HB. Secondary Spontaneous Pneumothorax in Patients with Sarcoma Treated with Pazopanib, a Case Control Study. BMC Cancer 18(1):937, 2018. e-Pub 2018. PMID: 30285733.
Ahmed T, Vial MR, Ost D, Stewart J, Hasan MA, Grosu HB. Non-small Cell Lung Cancer Transdifferentiation into Small Cell Lung Cancer: A Case Series. Lung Cancer 122:220-223, 2018. e-Pub 2018. PMID: 30032836.
Ost DE, Niu J, Zhao H, Grosu HB, Giordano SH. Quality Gaps and Comparative Effectiveness of Management Strategies for Recurrent Malignant Pleural Effusions. Chest 153(2):438-452, 2018. e-Pub 2018. PMID: 28864054.
Vakil E, Ost D, Vial MR, Stewart J, Sarkiss MG, Morice RC, Casal RF, Eapen GA, Grosu HB. Non-specific Pleuritis in Patients with Active Malignancy. Respirology 23(2):213-219, 2018. e-Pub 2018. PMID: 29024191.
Vial MR, O'Connell OJ, Grosu HB, Hernandez M, Noor L, Casal RF, Stewart J, Sarkiss M, Jimenez CA, Rice D, Mehran R, Ost DE, Eapen GA. Diagnostic Performance of Endobronchial Ultrasound-guided Mediastinal Lymph Node Sampling in Early Stage Non-small Cell Lung Cancer: A Prospective Study. Respirology 23(1):76-81, 2018. e-Pub 2018. PMID: 28857362.
Vakil E, Sarkiss M, Ost D, Vial MR, Casal RF, Eapen GA, Grosu HB. Safety of Monitored Anesthesia Care Using Propofol-Based Sedation for Pleuroscopy. Respiration 95(1):1-7, 2018. e-Pub 2018. PMID: 28918427.
Sheshadri A, Shah DP, Godoy M, Erasmus JJ, Song J, Li L, Evans SE, Chemaly RF, Dickey BF, Ost DE. Progression of the Radiologic Severity Index Predicts Mortality in Patients with Parainfluenza Virus-associated Lower Respiratory Infections. PLoS One 13(5):e0197418, 2018. e-Pub 2018. PMID: 29771962.
Vial MR, Eapen GA, Casal RF, Sarkiss MG, Ost DE, Vakil E, Grosu HB. Combined Pleuroscopy and Endobronchial Ultrasound for Diagnosis and Staging of Suspected Lung Cancer. Respir Med Case Rep 23:49-51, 2018. e-Pub 2018. PMID: 29276672.
Casal RF, Walsh G, McArthur M, Hill LR, Landaeta MF, Armas Villalba AJ, Ong P, Debiane L, Vakil E, Grosu HB, Jimenez CA, Ost D, Adachi R, Eapen GA. Bronchoscopic Laser Interstitial Thermal Therapy: An Experimental Study in Normal Porcine Lung Parenchyma. J Bronchology Interv Pulmonol 25(4):322-329, 2018. e-Pub 2018. PMID: 29771774.
Grosu HB, Kazzaz F, Vakil E, Molina S, Ost D. Sensitivity of Initial Thoracentesis for Malignant Pleural Effusion Stratified by Tumor Type in Patients with Strong Evidence of Metastatic Disease. Respiration 96(4):363-369, 2018. e-Pub 2018. PMID: 30016797.
Ontiveros N, Eapen-John D, Osorio N, Song J, Li L, Sheshadri A, Tiang X, Ghosh N, Vaporciyan A, Correa A, Walsh G, Grosu HB, Ost DE. Predicting Lung Function Following Lobectomy: A New Method to Adjust for Inherent Selection Bias. Respiration 96(5):434-445, 2018. e-Pub 2018. PMID: 30257257.
Grosu HB, Ost DE, Lee YI, Song J, Li L, Eden E, Rose K. Diaphragm Muscle Thinning in Subjects Receiving Mechanical Ventilation and Its Effect on Extubation. Respir Care 62(7):904-911, 2017. e-Pub 2017. PMID: 28351903.
Faiz SA, Pathania P, Song J, Li L, Balachandran DD, Ost DE, Morice RC, Shannon VR, Bashoura L, Eapen GA, Jimenez CA. Indwelling Pleural Catheters for Patients with Hematologic Malignancies: A 14-Year, Single-Center Experience. Ann Am Thorac Soc 14(6):976-985, 2017. e-Pub 2017. PMID: 28326798.
O'Connell OJ, Almeida FA, Simoff MJ, Yarmus L, Lazarus R, Young B, Chen Y, Semaan R, Saettele TM, Cicenia J, Bedi H, Kliment C, Li L, Sethi S, Diaz-Mendoza J, Feller-Kopman D, Song J, Gildea T, Lee H, Grosu HB, Machuzak M, Rodriguez-Vial M, Eapen GA, Jimenez CA, Casal RF, Ost DE. A Prediction Model to Help with the Assessment of Adenopathy in Lung Cancer (HAL). Am J Respir Crit Care Med 195(12):1651-1660, 2017. e-Pub 2017. PMID: 28002683.
Casal RF, Vial MR, Miller R, Mudambi L, Grosu HB, Eapen GA, Jimenez CA, Morice RC, Cornwell L, Ost D. What Exactly is a Centrally Located Lung Tumor? Results of an On-line Survey. Ann Am Thorac Soc 14(1):118-23, 2017. e-Pub 2017. PMID: 27854541.
Vial MR, Khan KA, O'Connell O, Peng SA, Gomez DR, Chang JY, Rice DC, Mehran R, Jimenez CJ, Grosu HB, Ost DE, Eapen GA. Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in the Nodal Staging of Stereotactic Ablative Body Radiotherapy Patients. Ann Thorac Surg 103(5):16000-1605, 2017. e-Pub 2017. PMID: 28027732.
Grosu HB, Vial MR, Vakil E, Casal RF, Eapen GA, Morice R, Stewart J, Sarkiss MG, Ost DE. Pleural Touch Preparations and Direct Visualization of the Pleura During Medical Thoracoscopy for the Diagnosis of Malignancy. Ann Am Thorac Soc 14(8):1326-1331, 2017. e-Pub 2017. PMID: 28406718.
Vakil E, Ost D, Vial MR, Stewart J, Sarkiss MG, Morice RC, Casal RF, Eapen GA, Grosu HB. Non-specific Pleuritic in Patients with Active Malignancy. Respirology, 2017. e-Pub 2017.
Vial MR, Stewart J, Lazarus DR, Eapen GA, Ost DE, Grosu HB, Jimenez CA. Unusual Aetiology of a Hilar Mass in a Man with History of Thyroid Cancer. Thorax 71(12):1167-1168, 2016. e-Pub 2016. PMID: 27422794.
Vial MR, Ost DE, Eapen GA, Jimenez CA, Morice RC, O'Connell O, Grosu HB. Intrapleural Fibrinolytic Therapy in Patients with Nondraining Indwelling Pleural Catheters. J Bronchology Interv Pulmonol 23(2):98-105, 2016. e-Pub 2016. PMID: 27058711.
Ost DE, Ernst A, Lei X, Kovitz KL, Benzaquen S, Diaz-Mendoza J, Greenhill S, Toth J, Feller-Kopman D, Puchalski J, Baram D, Karunakara R, Jimenez CA, Filner JJ, Morice RC, Eapen GA, Michaud GC, Estrada-Y-Martin RM, Rafeq S, Grosu HB, Ray C, Gilbert CR, Yarmus LB, Simoff M, Registry AB. Diagnostic Yield and Complications of Bronchoscopy for Peripheral Lung Lesions: Results of the AQuIRE Registry. Am J Respir Crit Care Med 193(1):68-77, 2016. e-Pub 2016. PMID: 26367186.
Vial MR, O'Connell JO, Grosu HB, Ost DE, Eapen GA, Jimenez CA. Needle Fracture During Endobronchial Ultrasound-guided Transbronchial Needle Aspiration. Am J Respir Crit Care Med 193(2):213-4, 2016. e-Pub 2016. PMID: 26378480.
O'Connell OJ, Rodriguez-Vial M, Ost DE, Jimenez CA, Grosu HB. Bronchoscopic Management of a Benign Obstructing Pedunculated Tumor. Ann Am Thorac Soc 12(11):1715-7, 2015. e-Pub 2015. PMID: 26540423.
Grosu HB, Ost DE, Morice RC, Eapen GA, Li L, Song J, Lei X, Lazarus DR, Casal RF, Jimenez CA. Mediastinal Granulomatous Inflammation and Overall Survival in Patients with a History of Malignancy. Ann Am Thorac Soc 12(10):1534-41, 2015. e-Pub 2015. PMID: 26284901.
Wiener RS, Gould MK, Arenberg DA, Au DH, Fennig K, Lamb CR, Mazzone PJ, Midthun DE, Napoli M, Ost DE, Powell CA, Rivera MP, Slatore CG, Tanner NT, Vachani A, Wisnivesky JP, Yoon SH, Clinical Practice ACOLCLCSI. An Official American Thoracic Society/American College of Chest Physicians Policy Statement: Implementation of Low-dose Computed Tomography Lung Cancer Screening Programs in Clinical Practice. Am J Respir Crit Care Med 192(7):881-91, 2015. e-Pub 2015. PMID: 26426785.
Grosu HB, Iliesiu M, Caraway NP, Medeiros LJ, Lei X, Jimenez CA, Morice RC, Casal RF, Ost D, Eapen GA. Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for the Diagnosis and Subtyping of Lymphoma. Ann Am Thorac Soc 12(9):1336-1344, 2015. e-Pub 2015. PMID: 26146788.
Ost DE, Sterman DH. Interventional Bronchoscopy in 2015. Removing Endoluminal and Methodological Obstructions. Ann Am Thorac Soc 12(9):1265-6, 2015. e-Pub 2015. PMID: 26372802.
Grosu HB, Morice RC, Sarkiss M, Bashoura L, Eapen GA, Jimenez CA, Faiz S, Lazarus DR, Casal RF, Ost DE. Safety of Flexible Bronchoscopy, Rigid Bronchoscopy, and Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in Patients with Malignant Space-occupying Brain Lesions. Chest 147(6):1621-1628, 2015. e-Pub 2015. PMID: 25393333.
Ost DE, Ernst A, Grosu HB, Lei X, Diaz-Mendoza J, Slade M, Gildea TR, Machuzak MS, Jimenez CA, Toth J, Kovitz KL, Ray C, Greenhill S, Casal RF, Almeida FA, Wahidi MM, Eapen GA, Feller-Kopman D, Morice RC, Benzaquen S, Tremblay A, Simoff M, Registry AB. Therapeutic Bronchoscopy for Malignant Central Airway Obstruction: Success Rates and Impact on Dyspnea and Quality of Life. Chest 147(5):1282-1298, 2015. e-Pub 2015. PMID: 25358019.
Casal RF, Lazarus DR, Kuhl K, Nogueras-González G, Perusich S, Green LK, Ost DE, Sarkiss M, Jimenez CA, Eapen GA, Morice RC, Cornwell L, Austria S, Sharafkanneh A, Rumbaut RE, Grosu H, Kheradmand F. Randomized Trial of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Under General Anesthesia versus Moderate Sedation. Am J Respir Crit Care Med 191(7):796-803, 2015. e-Pub 2015. PMID: 25574801.
Ong P, Grosu H, Eapen GA, Rodriguez M, Lazarus D, Ost D, Jimenez CA, Morice R, Bandi V, Tamara L, Cornwell L, Green L, Zhu A, Casal RF. Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Systematic Nodal Staging of Lung Cancer in Patients with N0 Disease by Computed Tomography and Integrated Positron Emission Tomography-computed Tomography. Ann Am Thorac Soc 12(3):415-9, 2015. e-Pub 2015. PMID: 25584815.
Ost DE, Ernst A, Grosu HB, Lei X, Diaz-Mendoza J, Slade M, Gildea TR, Machuzak M, Jimenez CA, Toth J, Kovitz KL, Ray C, Greenhill S, Casal RF, Almeida FA, Wahidi M, Eapen GA, Yarmus LB, Morice RC, Benzaquen S, Tremblay A, Simoff M. Complications Following Therapeutic Bronchoscopy for Malignant Central Airway Obstruction: Results of the AQuIRE Registry. Chest 148(2):450-471, 2015. e-Pub 2015. PMID: 25741903.
Godoy MC, Saldana DA, Rao PP, Vlahos I, Naidich DP, Benveniste MF, Erasmus JJ, Marom EM, Ost D. Multidetector CT Evaluation of Airway Stents: What the Radiologist Should Know. Radiographics 34(7):1793-806, 2014. e-Pub 2014. PMID: 25384279.
Ost DE, Jimenez CA, Lei X, Cantor SB, Grosu HB, Lazarus DR, Faiz SA, Bashoura L, Shannon VR, Balachandran D, Noor L, Hashmi YB, Casal RF, Morice RC, Eapen GA. Quality-adjusted Survival Following Treatment of Malignant Pleural Effusions with Indwelling Pleural Catheters. Chest 145(6):1347-1356, 2014. e-Pub 2014. PMID: 24480929.
Ost, D, Niu, J, Elting, LS, Buchholz, TA, Giordano, SH. Determinants of practice patterns and quality gaps in lung cancer staging and diagnosis. Chest 145(5):1097-1113, 2014. e-Pub 2014. PMID: 24202651.
Ost D, Niu J, Elting L, Buchholz TA, Giordano SH. Determinants of Practice Patterns and Quality Gaps in Lung Cancer Staging and Diagnosis. Chest 145:1097-1113, 2014. e-Pub 2014.
Ost DE, Niu J, Elting LS, Buchholz TA, Giordano SH. Quality gaps and comparative effectiveness in lung cancer staging and diagnosis. Chest 145(2):331-345, 2014. e-Pub 2014. PMID: 24091637.
Almeida FA, Casal RF, Jimenez CA, Eapen GA, Uzbeck M, Sarkiss M, Rice D, Morice RC, Ost DE. Quality Gaps and Comparative Effectiveness in Lung Cancer Staging: The Impact of Test Sequencing on Outcomes. Chest 144(6):1776-1782, 2013. e-Pub 2013. PMID: 23703671.
Garcia JB, Lei X, Wierda W, Cortes JE, Dickey BF, Evans SE, Ost DE. Pneumonia During Remission Induction Chemotherapy in Patients with Acute Leukemia. Ann Am Thorac Soc 10(5):432-440, 2013. e-Pub 2013. PMID: 23987587.
Casal RF, Iribarren J, Eapen G, Ost D, Morice R, Lan C, Cornwell L, Almeida FA, Grosu H, Jimenez CA. Safety and Effectiveness of Microdebrider Bronchoscopy for the Management of Central Airway Obstruction. Respirology 18(6):1011-5, 2013. e-Pub 2013. PMID: 23520982.
Grosu HB, Casal RF, Morice RC, Nogueras-González GM, Eapen GA, Ost D, Sarkiss MG, Jimenez CA. Bronchoscopic Findings and Bleeding Control Predict Survival in Patients with Solid Malignancies Presenting with Mild Hemoptysis. Ann Am Thorac Soc 4(4):342-349, 2013. e-Pub 2013. PMID: 23952853.
Grosu HB, Eapen GA, Morice RC, Jimenez CA, Casal RF, Almeida FA, Sarkiss MG, Ost DE. Stents are Associated with Increased Risk of Respiratory Infections in Patients Undergoing Airway Interventions for Malignant Airways Disease. Chest 144(2):441-449, 2013. e-Pub 2013. PMID: 23471176.
Ost DE, Jim Yeung SC, Tanoue LT, Gould MK. Clinical and Organizational Factors in the Initial Evaluation of Patients with Lung Cancer: Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-based Clinical Practice Guidelines. Chest 143(5 Suppl):e121S-e141S, 2013. e-Pub 2013. PMID: 23649435.
Eapen GA, Shah AM, Lei X, Jimenez CA, Morice RC, Yarmus L, Filner J, Ray C, Michaud G, Greenhill SR, Sarkiss M, Casal R, Rice D, Ost DE, Improvement Registry ACOCPQ, Education, (AQuIRE) Participants AE. Complications, Consequences, and Practice Patterns of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: Results of the AQuIRE Registry. Chest 143(4):1044-1053, 2013. e-Pub 2013. PMID: 23117878.
Yarmus LB, Akulian J, Lechtzin N, Yasin F, Kamdar B, Ernst A, Ost DE, Ray C, Greenhill SR, Jimenez CA, Filner J, Feller-Kopman D, Improvement Registry ACOCPQ, Education, (AQuIRE) Participants AE. Comparison of 21-gauge and 22-gauge Aspiration Needle in Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: Results of the American College of Chest Physicians Quality Improvement Registry, Education, and Evaluation Registry. Chest 143(4):1036-1043, 2013. e-Pub 2013. PMID: 23632441.
Casal RF, Bashoura L, Ost D, Chiu HT, Faiz SA, Jimenez CA, Morice RC, Eapen GA. Detecting Medical Device Complications: Lessons from an Indwelling Pleural Catheter Clinic. Am J Med Qual 28(1):69-75, 2013. e-Pub 2013. PMID: 22763365.
Yarmus LB, Akulian J, Lechtzin N, Yasin F, Ernst A, Ost DE, Ray C, Greenhill SR, Jimenez CA, Filner J, Feller-Kopman D. Comparison of 21-gauge and 22-gauge Aspiration Needle in Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: Results of the AQuIRE Registry. Chest 143:1036-1043, 2013. e-Pub 2013.
Grosu HB, Eapen GA, Morice RC, Jimenez CA, Casal RF, Almeida FA, Sarkiss MG, Ost DE. Stents are Associated with Increased Risk of Respiratory Infections in Patients Undergoing Airway Interventions for Malignant Airway Disease. Chest 144:441-449, 2013. e-Pub 2013.
Ost DE, Yeung J, Tanoue LT, Gould M. Clinical and Organizational Factors in the Initial Evaluation of Patients with Lung Cancer: Diagnosis and Management of Lung Cancer. Chest 143:e121S-141S, 2013. e-Pub 2013.
Casal RF, Staerkel GA, Ost D, Almeida FA, Uzbeck MH, Eapen GA, Jimenez CA, Nogueras-Gonzalez GM, Sarkiss M, Morice RC. Randomized Clinical Trial of Endobronchial Ultrasound Needle Biopsy with and without Aspiration. Chest 142(3):568-573, doi:10.1378/chest.11-0692, 2012. e-Pub 2012. PMID: 22156610.
Grosu HB, Jimenez CA, Eapen GA, Ost D, Moran C, Morice RC. The Iron Lady. Am J Respir Crit Care Med 186(5):460, 2012. e-Pub 2012. PMID: 22942346.
Nair A, Godoy MC, Holden EL, Madden BP, Chua F, Ost DE, Roos JE, Naidich DP, Vlahos I. Multidetector CT and Postprocessing in Planning and Assisting in Minimally Invasive Bronchoscopic Airway Interventions. Radiographics 32(5):E201-32, 2012. e-Pub 2012. PMID: 22977038.
Ost DE, Shah AM, Lei X, Godoy MC, Jimenez CA, Eapen GA, Jani P, Larson AJ, Sarkiss MG, Morice RC. Respiratory Infections Increase the Risk of Granulation Tissue Formation Following Airway Stenting in Patients With Malignant Airway Obstruction. Chest 141(6):1473-81, 2012. e-Pub 2012. PMID: 22194585.
Grosu HB, Morice RC, Almeida FA, Ost D, Eapen GA, Jimenez CA. A Flexible Knot to Untie. Am J Respir Crit Care Med 185(11):1244, 2012. e-Pub 2012. PMID: 22661525.
Ost DE, Gould MK. Decision Making in the Patient with Pulmonary Nodules. Am J Respir Crit Care Med 185(4):363-72, 2012. e-Pub 2012. PMID: 21980032.
Shah AM, Morice RC, Ost D, Eapen GA, Betancourt SL, Jimenez CA. High-riding Pericardial Recess Mimicking Metastatic Mediastinal Lymph Node. Am J Respir Crit Care Med 185(1):e1, 2012. e-Pub 2012. PMID: 22210796.
Ost DE, Ernst A, Lei X, Feller-Kopman D, Eapen GA, Kovitz KL, Herth FJ, Simoff M, Registry AB. Diagnostic Yield of Endobronchial Ultrasound Guided Transbronchial Needle Aspiration: Results of the AQuIRE Registry. Chest 140(6):1557-1566, 2011. e-Pub 2011. PMID: 21659432.
Peñuelas O, Frutos-Vivar F, Fernández C, Anzueto A, Epstein SK, Apezteguía C, González M, Nin N, Raymondos K, Tomicic V, Desmery P, Arabi Y, Pelosi P, Kuiper M, Jibaja M, Matamis D, Ferguson ND, Esteban A, Ventila Group VGAPOT, site PI. Characteristics and Outcomes of Ventilated Patients According to Time to Liberation from Mechanical Ventilation. Am J Respir Crit Care Med 184(4):430-7, 2011. e-Pub 2011. PMID: 21616997.
Lombardi R, Nin N, Lorente JA, Frutos-Vivar F, Ferguson ND, Hurtado J, Apezteguia C, Desmery P, Raymondos K, Tomicic V, Cakar N, González M, Elizalde J, Nightingale P, Abroug F, Jibaja M, Arabi Y, Moreno R, Matamis D, Anzueto A, Esteban A, Ventila Group VGAPOT, site PI. An Assessment of the Acute Kidney Injury Network Creatinine-based Criteria in Patients Submitted to Mechanical Ventilation. Clin J Am Soc Nephrol 6(7):1547-55, 2011. e-Pub 2011. PMID: 21700822.
Pelosi P, Ferguson ND, Frutos-Vivar F, Anzueto A, Putensen C, Raymondos K, Apezteguia C, Desmery P, Hurtado J, Abroug F, Elizalde J, Tomicic V, Cakar N, Gonzalez M, Arabi Y, Moreno R, Esteban A, Ventila Group VSGAPOT, site PI. Management and Outcome of Mechanically Ventilated Neurologic Patients. Crit Care Med 39(6):1482-92, 2011. e-Pub 2011. PMID: 21378554.
Kett DH, Azoulay E, Echeverria PM, Vincent JL, II investigators EPOIIIS(IGOIAPOTE, site PI. Candida Bloodstream Infections in Intensive Care Units: Analysis of the Extended Prevalence of Infection in Intensive Care Unit Study. Crit Care Med 39(4):665-70, 2011. e-Pub 2011. PMID: 21169817.
Filner JJ, Bonura EJ, Lau ST, Abounasr KK, Naidich D, Morice RC, Eapen GA, Jimenez CA, Casal RF, Ost D. Bronchoscopic Fibered Confocal Fluorescence Microscopy Image Characteristics and Pathologic Correlations. J Bronchology Interv Pulmonol 18(1):23-30, 2011. e-Pub 2011. PMID: 23169014.
Morice RC, Jimenez CA, Eapen GA, Mehran RJ, Keus L, Ost D. Using Quantitative Breath Sound Measurements to Predict Lung Function Following Resection. J Cardiothorac Surg 5(1):81, 2010. e-Pub 2010. PMID: 20939900.
Ost DE, Poch D, Fadel A, Wettimuny S, Ginocchio C, Wang XP. Mini-bronchoalveolar Lavage Quantitative Polymerase Chain Reaction for Diagnosis of Methicillin-resistant Staphylococcus aureus Pneumonia. Crit Care Med 38(7):1536-41, 2010. e-Pub 2010. PMID: 20473148.
Ernst A, Simoff M, Ost D, Michaud G, Chandra D, Herth FJ. A Multi-center, Prospective, Advanced Diagnostic Bronchoscopy Outcomes Registry. Chest 138(1):165-70, 2010. e-Pub 2010. PMID: 20363846.
Ost D, Eapen GA, Jimenez CA, Morice RC. Improving Procedural Training and Certification in Pulmonary Medicine. Chest 137(1):6-8, 2010. e-Pub 2010. PMID: 20051398.
Sterman DH, Mehta AC, Wood DE, Mathur PN, McKenna RJ, Ost DE, Truwit JD, Diaz P, Wahidi MM, Cerfolio R, Maxfield R, Musani AI, Gildea T, Sheski F, Machuzak M, Haas AR, Gonzalez HX, Springmeyer SC, IBV Valve US Pilot Trial Research Team IBV. A Multicenter Pilot Study of a Bronchial Valve for the Treatment of Severe Emphysema. Respiration 79(3):222-33, 2010. e-Pub 2010. PMID: 19923790.
Ozcakar B, Martinez CH, Morice RC, Eapen GA, Ost D, Sarkiss MG, Chiu HT, Jimenez CA. Does Pleural Fluid Appearance Really Matter? The Relationship Between Fluid Appearance and Cytology, Cell Counts, and Chemical Laboratory Measurements in Pleural Effusions of Patients with Cancer. J Cardiothorac Surg 5(1):63, 2010. e-Pub 2010. PMID: 20718978.
Springmeyer SC, Bolliger CT, Waddell TK, Gonzalez X, Wood DE, IBV Valve Pilot Trials Research Teams As part of the IBV Pilot trials team IBV, for trial SP. Treatment of Heterogeneous Emphysema Using the Spiration IBV Valves. Thorac Surg Clin 19(2):247-53, ix-x, 2009. e-Pub 2009. PMID: 19662968.
Ernst A, Simoff M, Ost D, Goldman Y, Herth FJF. Prospective Risk-adjusted Morbidity and Mortality Outcome Analysis After Therapeutic Bronchoscopic Procedures: Results of a Multi-institutional Outcomes Database. Chest 134(3):514-9, 2008. e-Pub 2008. PMID: 18641088.
Ost D, Shah R, Anasco E, Lusardi L, Doyle J, Austin C, Fein A. A Randomized Trial of CT Fluoroscopic-guided Bronchoscopy vs Conventional Bronchoscopy in Patients with Suspected Lung Cancer. Chest 134(3):507-13, 2008. e-Pub 2008. PMID: 18641093.
Ost D, Goldberg J, Rolnitzky L, Rom WN. Survival After Surgery in Stage IA and IB Non-small Cell Lung Cancer. Am J Respir Crit Care Med 177(5):516-23, 2008. e-Pub 2008. PMID: 18006887.
Corwin HL, Gettinger A, Fabian TC, May A, Pearl RG, Heard S, An R, Bowers PJ, Burton P, Klausner MA, Corwin MJ, EPO Critical Care Trials Group As part of EPI Trials Group EPO, site PI. Efficacy and Safety of Epoetin Alfa in Critically Ill Patients. N Engl J Med 357(10):965-76, 2007. e-Pub 2007. PMID: 17804841.
Wood DE, McKenna RJ, Yusen RD, Sterman DH, Ost DE, Springmeyer SC, Gonzalez HX, Mulligan MS, Gildea T, Houck WV, Machuzak M, Mehta AC. A Multicenter Trial of an Intrabronchial Valve for Treatment of Severe Emphysema. J Thorac Cardiovasc Surg 133(1):65-73, 2007. e-Pub 2007. PMID: 17198782.
Ost D, Tepper J, Mihara H, Lander O, Heinzer R, Fein A. Duration of Anticoagulation Following Venous Thromboembolism: A Meta-analysis. JAMA 294(6):706-15, 2005. e-Pub 2005. PMID: 16091573.
Ost D, Khanna D, Shah R, Hall CS, Shah S, Lesser M, Fein AM. Theory versus Practice: Impact of Spiral Computed Tomography on the Diagnosis of Pulmonary Embolism in a Community Hospital Setting. Respiration 71(5):450-7, 2004. e-Pub 2004. PMID: 15467321.
Bernard GR, Margolis BD, Shanies HM, Ely EW, Wheeler AP, Levy H, Wong K, Wright T, study group FTEEORHAPCUSIAPOTE, site PI. Extended Evaluation of Recombinant Human Activated Protein C United States Trial (ENHANCE US): A Single-arm, Phase 3B, Multicenter Study of Drotrecogin Alfa (Activated) in Severe Sepsis. Chest 125:2206-2216, 2004. e-Pub 2004.
Mojavarian A, Ost D. Tracheobronchial Glomus Tumor. J Bronchology 11:188-193, 2004. e-Pub 2004.
Spragg R, Lewis J, Walmrath H, Study Group EAFTVSGAPOTV, site PI. Effect of Recombinant Surfactant Protein C-based Surfactant on the Acute-respiratory Distress Syndrome. N Engl J Med 351:884-92, 2004. e-Pub 2004.
Ost DE, Hall CS, Joseph G, Ginocchio C, Condon S, Kao E, LaRusso M, Itzla R, Fein AM. Decision Analysis of Antibiotic and Diagnostic Strategies in Ventilator-associated Pneumonia. Am J Respir Crit Care Med 168(9):1060-7, 2003. e-Pub 2003. PMID: 12842855.
Friedman, DA, Shulman, L, Ost, D, Fein, AM. Dual Stenting of a Bronchoesophageal Fistula. Journal of Bronchology 10(4):272-275, 2003. e-Pub 2003.
Ernst, A, Freitag, L, Feller-Kopman, D, Locicero, J, Ost, D. Photodynamic Therapy for Endobronchial Obstruction is Safely Performed with Flexible Bronchoscopy. Journal of Bronchology 10(4):260-263, 2003. e-Pub 2003.
Hall, CS, Ost, D. Effectiveness of programs to decrease antimicrobial resistance in the intensive care unit. Seminars in Respiratory Infections 18(2):112-121, 2003. e-Pub 2003. PMID: 12840792.
Investigators TM. Subcutaneous Fondaparinux versus Intravenous Unfractionated Heparin in the Initial Treatment of Pulmonary Embolism. N Engl J Med 349:1695-1702, 2003. e-Pub 2003.
Ernst A, Freitag L, Feller-Kopman D, LoCicero J, Ost D. Photodynamic Therapy for Endobronchial Obstruction is Safely Performed with Flexible Bronchoscopy. J Bronchol Intervent Pulmonol 10:260-263, 2003. e-Pub 2003.
Friedman D, Shulman L, Ost D, Fein A. Dual Stenting of Bronchoesophageal Fistula. J Bronchol 10:272-275, 2003. e-Pub 2003.
Ost, D, Derosiers, A, James Britt, E, Fein, AM, Lesser, M, Mehta, A. Assessment of a bronchoscopy simulator. American journal of respiratory and critical care medicine 164(12):2248-2255, 2002. e-Pub 2002. PMID: 11751195.
Khanna, D, Ost, D. How to identify and manage life-threatening infections of the upper airway, Part 2. Journal of Critical Illness 17(4):134-140, 2002. e-Pub 2002.
Mehrishi, S, Ost, D. Photodynamic therapy. Journal of Bronchology 9(3):218-222, 2002. e-Pub 2002.
Ost D, Rozenshtein A, Saffran L, Snider A. The Negative Predictive Value of Spiral Computed Tomography for the Diagnosis of Pulmonary Embolism in Patients with Nondiagnostic Ventilation-perfusion Scans. Am J Med 110(1):16-21, 2001. e-Pub 2001. PMID: 11152860.
Ost D, DeRosiers A, Britt E J, Fein A, Lesser M, Mehta A. Assessment of a Bronchoscopy Simulator. Am J Respir Crit Care Med 164:1-8, 2001. e-Pub 2001.
Saffran, L, Ost, D, Fein, AM, Schiff, MJ. Outpatient pleurodesis of malignant pleural effusions using a small-bore pigtail catheter. Chest 118(2):417-421, 2000. e-Pub 2000. PMID: 10936134.
Shah, SK, Ost, D. Photodynamic therapy. Chest 118(5):1419-1423, 2000. e-Pub 2000. PMID: 11083695.
Ost, D. Photodynamic therapy in lung cancer. ONCOLOGY 14(3):379-391, 2000. e-Pub 2000. PMID: 10742965.
Saffron LS, Ost D, Fein AM, Schiff MJ. Outpatient Pleurodesis of Malignant Pleural Effusions, Using a Small Bore Pigtail Catheter. Chest 118:417-22, 2000. e-Pub 2000.
Shah S, Ost D. Photodynamic Therapy: A Case Series Demonstrating its Role in Mechanically Ventilated Patients. Chest 118:1419-1423, 2000. e-Pub 2000.
Ost, D, Joseph, C, Sogoloff, H, Menezes, G. Primary pulmonary melanoma. Mayo Clinic Proceedings 74(1):62-66, 1999. e-Pub 1999. PMID: 9987535.
Ost D, Joseph C, Sogoloff H, Menezes G. Primary Pulmonary Melanoma: Case Report and Literature Review. Mayo Clinic Proc 74:62-66, 1999. e-Pub 1999.
Saffran, L, Schiff, MJ, Ost, D, Russo, RM, Feinsilver, SH, Fein, AM. Outpatient pleurodeses of malignant pleural effusions using a small bore pigtail catheter. Chest 114(4 SUPPL):365S, 1998. e-Pub 1998.
Ost, D, Corbridge, T. Independent lung ventilation. Clinics in Chest Medicine 17(3):591-601, 1996. e-Pub 1996. PMID: 8875013.
Ost, D, Yeldandt, A, Cugell, D. Acute sarcoid myositis with respiratory muscle involvement. Chest 107(3):879-882, 1995. e-Pub 1995. PMID: 7874972.
Ost D, Yeldandi A, Cugell D. Acute Sarcoid Myositis: Case Report and Review of the Literature. Chest 107:879-82, 1995. e-Pub 1995.
Sachs, MK, Huang, CM, Ost, D, Jungkind, DL. Failure of dithiothreitol and pronase to reveal a false-positive cryptococcal antigen determination in cerebrospinal fluid. American journal of clinical pathology 96(3):381-384, 1991. e-Pub 1991. PMID: 1877537.
Owen, CS, Sykes, NL, Shuler, RL, Ost, D. Non-calcium environmental sensitivity of intracellular Indo-1. Analytical Biochemistry 192(1):142-148, 1991. e-Pub 1991. PMID: 2048716.
Sachs MK, Huang CM, Ost D, Jungkind DL. Failure of Dithiothreitol and Pronase to Reveal a False-positive Cryptococcal Antigen Determination in Cerebrospinal Fluid. Am J Clin Pathol 96:381-4, 1991. e-Pub 1991.
Owen CS, Sykes NL, Shuler RL, Ost D. Non-calcium Environmental Sensitivity of Intracellular Indo-1. Analytical Biochemistry 192:142-8, 1991. e-Pub 1991.

Book Chapters

Sagar, AS, Ost, D. The Future of Interventional Pulmonology, 263-270, 2024.
Virdi SH, Gershengorn HB, Chang SY, Ost DE, Cervellione KL, Fein AM. Defining and Measuring Patient Safety in the Critical Care Unit. In: Intensive Care Medicine. 9th. McGraw-Hill, 2023.
Ost DE. Multimodality Approach to Malignant Airway Obstruction. In: Practical Guide To Interventional Pulmonology. Elsevier, 2023.
Sagar A, Ost D. The Future of Interventional Pulmonology. In: Flexible Bronchoscopy. 4th. Wiley, 2019.
Gershengorn HB, Chang SY, Ost DE, Cervellione KL, Fein AM. Defining and Measuring Patient Safety in the Critical Care Unit. In: Intensive Care Medicine. 8th. McGraw-Hill, 2018.
Ong P, Ost D. Lung Cancer Epidemiologic Changes: Implications in Diagnosis and Therapy. In: Interventions in Pulmonary Medicine. Springer, Cham, 323-332, 2018.
Ong, P, Ost, D. Lung cancer epidemiologic changes, 323-332, 2017.
Ost, D. Photodynamic therapy for palliation of lung cancer, 287-304, 2016.
Lee, R, Ost, D. Advanced Bronchoscopic Techniques for Diagnosis of Peripheral Pulmonary Lesions, 186-199, 2016.
Ost D. Approach to the Patient with Pulmonary Nodules. In: Fishman’s Pulmonary Diseases and Disorders. 5th. McGraw-Hill, 2014.
Ost, D. Photodynamic Therapy for Endobronchial Tumors, 155-166, 2008.
Fein A, Chang S, Ost D, Heffner J, Merwin S. Defining and Measuring Safety in the Intensive Care Unit. In: Intensive Care Medicine. Lippincott, Williams and Wilkins, 2007.
Ost D, Fein A. The Solitary Pulmonary Nodule: A Systematic Approach. In: Pulmonary Diseases and Disorders. McGraw Hill, 2007.
Ost D. Bronchoscopy Simulator Assessment. In: Practical Healthcare Simulations. Elsevier Science/Hanley Belfus, 475-492, 2004.
Ost D. Photodynamic Therapy for Palliation of Lung Cancer. In: Interventional Pulmonary Medicine. Marcel Dekker, 287-304, 2004.
Ost D, Fein A, Feinsilver S, Shah R. Non-Resolving Pneumonia. In: UpToDate, 2001.
Ost D, Rozenshstein A, Fein A. Nonresolving Pneumonia. In: Community-Acquired Pneumonia. Plenum Publishing, pages 386-413, 2001.
Ost D, Corbridge T. Chest Tubes. In: Pulmonary and Respiratory Therapy Secrets. 2nd. Hanley and Belfus, 68-73, 2001.
Ost D. Natural History of Pneumonia. In: Diagnosis and Management of Pneumonia and Other Respiratory Infections. Professional Communications, 1999.
Ost D. Sindrome de la Neumonia de Resolucion Lenta. In: Infecciones Respiratorias en UCI. Springer-Verlag Iberica, pages 28-64, 1999.
Ost D. Parapneumonic Effusions and Empyema. In: Diagnosis and Management of Pneumonia and Other Respiratory Infections. Professional Communications, 1999.
Ost D. Diagnosis of Pneumonia Which Fails to Resolve. In: Diagnosis and Management of Pneumonia and Other Respiratory Infections. Professional Communications, 1999.

Books (edited and written)

Wahidi A, Ost DE. Practical Guide to Interventional Pulmonology. Elsevier, 2023.
Fein, AM, Kamholz, S, Ost, D. Respiratory emergencies, 2006.
Fein A, Kamholz S, Ost D. Respiratory Emergencies. Hodder Arnold, 2006.
Fein A, Grossman R, Ost D, Farber B. Diagnosis and Management of Pneumonia and Other Respiratory Infections. Professional Communications, 1999.

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Selected Presentations & Talks

Formal Peers

2025. U.S. Pleural Research Day. Nashville, Tennessee, US.
2019. Medical Pleuroscopy and Indwelling Pleural Catheters. Invited. Burlington, MA, US.
2018. Endobronchial Lung Volume Reduction and Thermoplasty. Invited. Burlington, MA, US.
2017. Advanced Diagnostic and Therapeutic Bronchoscopy. Invited. New York, NY, US.
2017. Bronchial Thermoplasty and Bronchoscopic Lung Volume Reduction. Invited. Burlington, MA, US.
2016. Endobronchial Lung Volume Reduction. Invited. Burlington, MA, US.
2015. Endobronchial Lung Volume Reduction and Bronchial Thermoplasty. Invited. Burlington, MA, US.
2015. Billing and Coding for Interventional Bronchoscopy. Invited. Burlington, MA, US.
2014. Lung Cancer Staging and Diagnosis with EBUS. Invited. Shanghai, CN.
2014. Lung Cancer Staging and Diagnosis with EBUS. Invited. Shanghai, CN.
2014. Airway Stenting. Invited. Detroit, MI, US.
2014. Coding and Billing for Bronchoscopy: Developing a Sustainable Program. Invited. Burlington, MA, US.
2014. Bronchoscopic Treatment of Emphysema. Invited. Burlington, MA, US.
2014. New Developments in Lung Cancer Staging and Diagnosis. Invited. New York, NY, US.
2013. New Developments in Airway Stenting. Invited. Detroit, MI, US.
2013. Bronchoscopic Lung Volume Reduction. Invited. Burlington, MA, US.
2013. Interventional Pulmonology Coding and Billing. Invited. Burlington, MA, US.
2012. Management of the Solitary Pulmonary Nodule. Invited. Omaha, NE, US.
2012. Update on Airway Stenting. Invited. New York, NY, US.
2012. Interventional Pulmonology and the Business of Bronchoscopy. Invited. New York, NY, US.
2012. Endobronchial Lung Volume Reduction. Invited. Burlington, MA, US.
2012. The Business of Bronchoscopy: Billing and Coding. Invited. Burlington, MA, US.
2012. Interventional Pulmonology Year in Review 2012. Invited. Burlington, MA, US.
2012. Airway Stenting. Invited. Detroit, MI, US.
2011. Interventional Pulmonology and the Business of Bronchoscopy. Invited. New York, NY, US.
2011. Endobronchial Lung Volume Reduction. Invited. Boston, MA, US.
2011. Advances in Airway Stenting. Invited. Detroit, MI, US.
2010. Introduction to Airway Stenting. Invited. Detroit, MI, US.
2010. Interventional Pulmonary Cases and Applications. Invited. Atlanta, GA, US.
2009. The Role of Simulation Training in Fellowship Education. Invited. Burlington, MA, US.
2008. Update on Bronchoscopic Treatments for Emphysema and Asthma. Invited. New York, NY, US.
2008. Bronchoscopic Treatments for Emphysema. Invited. New York, NY, US.
2008. Bronchoscopy for Asthma and Emphysema - New Paradigms in Treatment. Invited. New York, NY, US.
2008. Photodynamic Therapy for Lung Cancer and Bronchial Thermoplasty for Asthma. Visiting. Beijing, CN.
2008. Interventional Bronchoscopy for Asthma. Invited. Burlington, MA, US.
2008. Training in Interventional Pulmonology. Invited. Houston, TX, US.
2007. Interventional Pulmonology: Bronchoscopy for Emphysema?. Invited. Norwalk, CT, US.
2007. New Developments in Interventional Pulmonology for Emphysema and Asthma. Visiting, US.
2007. Interventional Bronchoscopy: Managing and Coding for Interventional Pulmonology Procedures. Invited. Burlington, MA, US.
2005. Interventional Pulmonology Update. Visiting, FR.
2005. Interventional Bronchoscopy. Invited. New York, NY, US.
2005. Bronchoscopic Lung Volume Reduction for Emphysema. Invited. New York, NY, US.
2004. Interventional Bronchoscopy: Anesthesia Methods for Interventional Bronchoscopy. Invited, FR.
2004. Interventional Bronchoscopy: Anesthesia Methods for Interventional Bronchoscopy. Invited, FR.
2004. Interventional Bronchoscopy: Lung Cancer Screening with Low-Dose CT and Autofluorescence. Invited, FR.
2004. Interventional Bronchoscopy: Lung Cancer Screening with Low-dose CT and Autofluorescence. Invited, FR.
2004. Antibiotic Resistance and Ventilator Associated Pneumonia: A decision analysis approach. Visiting, US.
2004. New Developments in COPD: Bronchoscopic Lung Volume Reduction. Invited. Queens, NY, US.
2004. Pleurodesis with Tubes and Catheters. Invited. Boston, MA, US.
2003. Pneumonia and Drug Resistance. Invited, NY, US.
2003. Photodynamic Therapy in Lung Cancer. Invited. Boston, MA, US.
2002. New Approaches to the Solitary Pulmonary Nodule. Invited, US.
2002. Interventional Bronchoscopy: New Developments in Airway Stents. Invited, US.
2002. New Developments in Interventional Bronchoscopy. Invited, US.
2002. Management of Tracheal Stenosis. Invited, US.
2002. Rigid Bronchoscopy and Dumon Stent Placement. Invited, US.
2001. Interventional Bronchoscopy. Invited, US.
2001. Interventional Pulmonology. Invited. Stony Brook, NY, US.
2001. New Developments in the Diagnosis and Treatment of COPD. Invited, US.
2001. Antibiotic Resistance in Nosocomial Pneumonia. Invited, US.
2000. Antibiotic Resistance in Community Acquired and Nosocomial Pneumonia. Invited, US.
2000. Pneumonia in the Geriatric Population. Invited, US.
2000. Community Acquired Pneumonia and Drug Resistance. Invited, US.
2000. New Methods of Lung Cancer Diagnosis and Screening. Invited, US.
1999. Nosocomial Pneumonia and Drug Resistance. Invited, US.
1999. Photodynamic Therapy for Advanced Lung Cancer: Clinical Approach and Guidelines. Invited, US.
1999. New Approaches to Nosocomial Pneumonia. Invited, US.
1999. Multimodality Therapy for Lung Cancer: A Pulmonary Perspective. Invited, US.
1999. Influenza in the New Millennium. Invited, US.
1998. New Techniques in Lung Cancer Diagnosis and Staging. Invited, US.
1998. Photodynamic Therapy and Interventional Pulmonary Medicine. Invited, US.
1998. Photodynamic Therapy in Lung Cancer. Invited, US.
1998. Nosocomial Pneumonia: An Evidence Based Approach. Invited, US.
1998. Therapy of Community Acquired Pneumonia. Invited, US.
1998. New Developments in Community Acquired Pneumonia: An Evidence Based Approach. Invited, US.
1998. Photodynamic Therapy in Lung Cancer. Invited, US.
1998. Drug Resistance and Pneumonia. Invited, US.
1998. Bronchoscopic Treatment of Endobronchial Disease: Assessment of Techniques. Invited, US.
1998. Photodynamic Therapy in Lung Cancer. Invited, US.
1998. New Treatments for COPD. Invited, US.
1998. Clinical Problems in Community Acquired Pneumonia. Invited, US.
1997. Therapy of Community Acquired Pneumonia. Invited, US.
1997. Clinical Guidelines in Community Acquired Pneumonia. Invited, US.
1997. New Approaches to Community Acquired Pneumonia. Invited, US.
1997. Interventional Pulmonary Medicine in Lung Cancer. Invited. Manhasset, NY, US.

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Grant & Contract Support

Date:	2023 - Present
Title:	A Case Control Study for the Development of Multiomics Blood Tests for Cancer Screening
Funding Source:	Freenome, Inc
Role:	Site Principal Investigator

Date:	2023 - Present
Title:	NIO Laser Imaging System with the NIO Lung Cancer Reveal image analysis module
Funding Source:	Invenio Imaging, Inc
Role:	PI

Date:	2023 - 2025
Title:	A multicenter study in bronchoscopy combining Stimulated Raman Histology with artificial Intelligence for rapid lung cancer detection
Funding Source:	Invenio Imaging Inc
Role:	Co-PI
ID:	1R44CA281581-01

Date:	2019 - 2021
Title:	A Prospective Evaluation of the Clinical Utility for the Ion Endoluminal System
Funding Source:	Intuitive Surgical, Inc
Role:	PI

Date:	2017 - 2020
Title:	Decision Analysis of Robotic Bronchoscopy for Peripheral Pulmonary Nodules and Masses
Funding Source:	Intuitive Surgical, Inc
Role:	PI

Date:	2016 - 2017
Title:	Prospective Analysis of Quantitative CT for Prediction of Lung Function Post Surgical Resection 1
Funding Source:	VIDA Diagnostics
Role:	PI
ID:	00004290

Date:	2015 - 2019
Title:	Retrospective Analysis of Viral Upper Respiratory Tract Infections and Subsequent Pneumonia in Patients with Hematologic Malignancies
Funding Source:	Pulmotect, LLC
Role:	PI
ID:	00003699

Date:	2015 - 2018
Title:	A Multi-Center Trial of the ProLung Test as an Adjunct to Lung CT in the Evaluation of Patients with Pulmonary Lesions Suspicious for Lung Cancer
Funding Source:	Fresh Medical Laboratories
Role:	PI

Date:	2014 - 2016
Title:	Development of a Drug-eluting Airway Stent for Malignant Airway Obstruction
Funding Source:	The University of Texas MD Anderson Cancer Center
Role:	PI
ID:	Institutional Research Grant Program

Date:	2011 - 2013
Title:	Comparative Effectiveness of Bronchoscopic Interventions for Malignant Airway Obstruction
Funding Source:	The University of Texas MD Anderson Cancer Center
Role:	PI
ID:	Institutional Research Grant Program

Date:	2011 - 2013
Title:	A Multicenter Bronchoscopy Registry and Quality Improvement Collaborative for Comparative Effectiveness and Safety Research
Funding Source:	The University of Texas Healthcare Safety & Effectiveness Grants Program
Role:	PI
ID:	OGC Grant #137700 Collaborative Efforts in Clinical Programs

Date:	2011 - 2013
Title:	Comparative Effectiveness of Bronchoscopic Interventions for Malignant Airway Obstruction
Funding Source:	The University of Texas Healthcare Safety & Effectiveness Grants Program
Role:	PI
ID:	Quality of Care Research Grant

Date:	2010 - 2012
Title:	Comparative Effectiveness of Indwelling Pleural Catheters versus Thoracoscopic Pleurodesis for Treatment of Malignant Pleural Effusions
Funding Source:	The University of Texas MD Anderson Cancer Center
Role:	PI
ID:	Institute for Cancer Care Excellence

Date:	2010 - 2012
Title:	FDA Monitoring of Bronchoscopy Outcomes and Safety. FDA Solicitation Number, FDA-09-1232
Funding Source:	ACCP Quality Improvement Registry, Evaluation, and Education (AQuIRE) system
Role:	PI
ID:	FDA Order Number: HHSF223200910460P

Date:	2009 - Present
Title:	An International Multi-Center Interventional and Diagnostic Bronchoscopy Registry
Funding Source:	Bronchoscopy Registry
Role:	PI

Date:	2007 - 2007
Title:	A Prospective, Randomized, Controlled Multicenter Clinical Trial to Evaluate the Safety and Effectiveness of the IBV™ Valve System for the Treatment of Severe Emphysema
Funding Source:	Spiration
Role:	PI

Date:	2006 - 2006
Title:	Quantitative PCR for the Diagnosis of MRSA Ventilator Associated Pneumonia
Funding Source:	Kimberly Clark
Role:	PI

Date:	2006 - 2007
Title:	A Randomized, Double-blind Study to Evaluate the Safety and Effectiveness of the Exhale® Drug-Eluting Stent in Homogeneous Emphysema Subjects with Severe Hyperinflation
Funding Source:	Broncus Technologies
Role:	PI

Date:	2006 - 2007
Title:	Computer Assisted Ultrathin Bronchoscopy
Funding Source:	NIH/NCI
Role:	Co-I
ID:	NIH 5 R21 CA116888

Date:	2004
Title:	Pilot Study of IBV Investigational Device, FDA Pre-IDE Reference Number I010284
Funding Source:	Spiration
Role:	PI

Date:	2004
Title:	Second International Study of Mechanical Investigation
Funding Source:	VENTILA Study Group
Role:	PI

Date:	2003 - 2003
Title:	Efficacy and Safety of Dtrotrecogin Alfa (Activated) in Adult Patients with Early Stage Severe Sepsis
Funding Source:	Lilly
Role:	PI

Date:	2003 - 2004
Title:	A Phase 2, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of a Recombinant Chimeric Monoclonal Antibody Against (Novel Substance) in Hospitalized Patients with Community-acquired Pneumonia and Sepsis
Funding Source:	ICOS
Role:	PI

Date:	2003 - 2003
Title:	Van Gogh Pulmonary Embolism Trial
Funding Source:	Organon
Role:	PI

Date:	2003
Title:	A Multicenter, International, Randomized, Open-label, Assessor-blind, Non-inferiority Study Comparing the Efficacy and Safety of Once-weekly (Novel Substance) with the Combination of LMW Heparin and Vitamin K Antagonist in the Treatment of Symptomatic Pulmonary Embolism
Funding Source:	Sanofi-Aventis
Role:	PI

Date:	2003
Title:	(Novel Device) Pivotal Study in Emphysema
Funding Source:	Spiration, Inc
Role:	PI

Date:	2002 - 2003
Title:	A Phase III Study to Demonstrate the Safety and Efficacy of Recombinant Platelet-Activating (Novel Substance) for Reducing 28 Day AllA Double-Blind, Placebo-Controlled, Parallel, Multicenter Study on Extended VTE Prophylaxis in Acutely Ill Medical Patients with Prolonged Immobilization
Funding Source:	Aventis
Role:	PI

Date:	2002 - 2003
Title:	Antibiotic Resistance Patterns and Strategies for Nosocomial Pneumonia
Funding Source:	Elan Pharmaceuticals
Role:	PI

Date:	2002 - 2003
Title:	Application of CT Fluoroscopy and Virtual Bronchoscopy for Diagnosis and Treatment of Lung Cancer
Funding Source:	General Electric
Role:	PI

Date:	2002 - 2004
Title:	Antibiotic Resistance Patterns and Strategies for Nosocomial Pneumonia
Funding Source:	Elan Pharmaceuticals
Role:	PI

Date:	2001 - 2003
Title:	A Phase III Study to Demonstrate the Safety and Efficacy of Recombinant Platelet-Activating (Novel Substance) for Reducing 28 Day All Cause Mortality in Patients with Severe Sepsis
Funding Source:	ICOS
Role:	PI

Date:	2001 - 2003
Title:	A Pilot Study of Routine Surveillance Cultures of High-Risk Patients Using the Combicath to Guide Antibiotic Selection for Nosocomial Pneumonia
Funding Source:	Kol Biomedical
Role:	PI

Date:	2001 - 2002
Title:	A Double Blind, Placebo-Controlled, Study of (Novel Substance) A Lipid A Antagonist, Administered by Twice Daily Intravenous Infusions in Patients with Severe Sepsis
Funding Source:	Eisai
Role:	Sub-investigator

Date:	2001
Title:	Effectiveness of Low Dose Theophylline as Add-On Therapy in the Treatment of Asthma (The Lo-Do Trial)
Funding Source:	American Lung Association
Role:	Sub-investigator

Date:	2001 - 2002
Title:	Multicenter, Double Blind, Placebo Controlled, Randomized, Phase III Study of a Recombinant Coagulation Inhibitor in Severe Sepsis
Funding Source:	Chiron
Role:	PI

Date:	2001 - 2002
Title:	A Phase II b Study to Determine the Efficacy and Safety of (Novel Substance) PLA Inhibitor in Patients with Severe Sepsis
Funding Source:	Shionogi & Lilly
Role:	Sub-investigator

Date:	2001 - 2002
Title:	AA Randomized Pilot Study for the Assessment of Bronchoscopy Guided by Computerized Axial Tomography Fluoroscopy
Funding Source:	American Lung Association
Role:	PI

Date:	2001
Title:	A Double-blind, Efficacy and Safety Study of the Oral Direct Thrombin Inhibitor (Novel Substance) versus Standard Therapy [Enoxaparin and Warfarin (Coumadin)] in Patients with Acute, Symptomatic Deep Vein Thrombosis with or without Pulmonary Embolism (THRIVE V)
Funding Source:	Astrazeneca
Role:	PI

Date:	2001
Title:	A Phase II Study to Determine the Efficacy and Safety of (Novel Substance) in Subjects with Acute Lung Injury
Funding Source:	Lilly
Role:	PI

Date:	2001 - 2002
Title:	A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Dose-Ranging, Evaluation of the Safety and Efficacy of [Novel Substance] in Patients with Acute Respiratory Distress Syndrome
Funding Source:	Suntory
Role:	PI

Date:	2001
Title:	A Phase III Study to Demonstrate the Safety and Efficacy of Recombinant Platelet-Activating (Novel Substance) for Reducing 28 Day All Cause Mortality in Patients with Severe Sepsis
Funding Source:	Smith-Kline
Role:	PI

Date:	2001
Title:	Long-Term Follow-Up of Survivors from the PROWESS Trial (An Observational Study, F1K-MC-EVBI
Funding Source:	Lilly
Role:	PI

Date:	2001 - 2002
Title:	An Open-Label Study of Recombinant [Novel Substance] in Severe Sepsis, F1K-MC-EVBE
Funding Source:	Eli-Lilly
Role:	PI

Date:	2000
Title:	Double-Blind, Placebo-Controlled, Crossover Trial of the Safety of Inactivated Influenza Vaccine in Adults and Children with Asthma
Funding Source:	American Lung Association
Role:	Sub-investigator
ID:	American Lung Association Asthma Clinical Research Center Grant

Date:	2000
Title:	An Open Label Pilot Study of the Safety and Efficacy of Inhaled Aminoglycosides
Funding Source:	Pathogenesis
Role:	Sub-investigator

Date:	2000 - 2003
Title:	A Multicentre, Randomized, Open-Label Study Comparing the Efficacy and Safety of Once Daily (o.d.) Pentasaccharide versus Adjusted-dose Intravenous (IV) Unfractionated Heparin (UFH) in the Initial Treatment of Acute Symptomatic Pulmonary Embolism (PE),
Funding Source:	Sanofi
Role:	PI

Date:	2000
Title:	A Multicenter, Multinational, Double-Blind, Placebo-Controlled, Group Comparative Study to Investigate the Effects of a Combined Beta-Agonist/Dopamine Agonist via pMDI Compared with a Beta-Agonist in Adult Patients with COPD
Funding Source:	Astra-Zeneca
Role:	PI

Date:	2000
Title:	MATISSE-DVT Study - “A Multicentre, Randomized, Double Blind Study Comparing the Efficacy and Safety of Once Daily (O.D.) Pentasacharide Versus Twice Daily (B.I.D.) Enoxaparin in the Initial Treatment of Acute Symptomatic Deep Venous Thrombosis Trial
Funding Source:	Sanofi
Role:	Sub-investigator

Date:	2000
Title:	An International, Multicenter, Uncontrolled, Open Evaluation of a New Vasodilator Plus Conventional Therapy in Patients with Pulmonary Hypertension: A Continuation Study
Funding Source:	United Therapeutics
Role:	PI

Date:	1999 - 2001
Title:	Efficacy of a Growth Factor in the Critically Ill Patient: A Randomized, Double-blind, Placebo-Controlled Trial
Funding Source:	Ortho Biotech
Role:	Sub-Investigator

Date:	1999 - 2000
Title:	A Synthetic Surfactant Replacement for the Treatment of Acute Respiratory Distress Syndrome (ARDS), A Randomized, Multinational, Multicenter, Parallel Group, Double Blind
Funding Source:	Altana
Role:	PI

Date:	1999
Title:	A Multicenter, Randomized, Open Label Study to Compare the Safety and Efficacy of a Fluoroquinolone with that of a Carbepenem in the Treatment of Nosocomial Pneumonia
Funding Source:	R.W. Johnson Research Institute
Role:	PI

Date:	1999
Title:	A Comparative Study of the Safety, Efficacy, and Effectiveness of a Macrolide Extended-Release Formulation and a Beta-lactam/Beta-Lactamase Combination for the Treatment of Subjects with Acute Exacerbations of Chronic Bronchitis
Funding Source:	Abbott
Role:	Sub-investigator

Date:	1998
Title:	A Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of an Antipseudomonal Penicillin and a Carbepenem Administered Intravenously Every Six Hours to Treat Nosocomial Pneumonia in Hospitalized Patients
Funding Source:	Wyeth Ayerst
Role:	Sub-Investigator

Date:	1998
Title:	Comparison of the Safety and Efficacy of a Macrolide to a Fluoroquinolone for the Treatment of Community Acquired Pneumonia
Funding Source:	Abbott
Role:	Sub-investigator

Date:	1998 - 1999
Title:	Unknown, PROWESS (Recombinant Anticoagulant Worldwide Evaluation in Severe Sepsis): A Phase III Study to Determine the Efficacy and Safety for a New Recombinant Anticoagulant in Severe Sepsis
Funding Source:	Eli Lilly
Role:	Sub-Investigator

Date:	1998
Title:	A Randomized Double Blind Parallel Group Trial Evaluating the Safety and Efficacy of the Diskus Formulations of a Long-Acting Beta Agonist and an Inhaled Corticosteroid Individually and in Combination as Compared to Placebo in COPD Patients
Funding Source:	GlaxoWellcome
Role:	PI

Date:	1998
Title:	A Comparative Study of the Efficacy of a Macrolid to an Azolide for the Treatment of Patients with Acute Exacerbations of Chronic Bronchitis
Funding Source:	Abbott
Role:	PI

Date:	1998
Title:	Safety and Efficacy of a Surfactant Replacement when Administered by Bronchopulmonary Segmental Lavage Compared to Standard of Care in Adults with Predominantly Direct Causes of Acute Respiratory Distress (ARDS)
Funding Source:	Discovery Laboratories
Role:	Sub-investigator

Date:	1997 - 1998
Title:	Randomized Placebo-Controlled Trial of an Inhibitor of the Inflammatory Cascade in Sepsis with Hyperinflammatory Response
Funding Source:	Knoll
Role:	Sub-investigator

CV information above last modified May 07, 2025

David E. Ost, M.D., M.P.H., F.A.C.P.

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David E. Ost, M.D., M.P.H., F.A.C.P.

Present Title & Affiliation

Primary Appointment

Research Interests

Education & Training

Postgraduate Training

Board Certifications

Experience & Service

Academic Appointments

Other Appointments/Responsibilities

Institutional Committee Activities

Professional Memberships

Selected Publications

Peer-Reviewed Articles

Book Chapters

Books (edited and written)

Selected Presentations & Talks

Formal Peers

Grant & Contract Support

Patient Reviews

Request an Appointment

Related Links

Care Centers and Clinics

Departments and Divisions

Labs

Clinical Trials

Help #EndCancer

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