Dershan Luo
Department of Radiation Physics, Division of Radiation Oncology
About Dr. Luo
BioStatement
Present Title & Affiliation
Primary Appointment
Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, HOUSTON, TX
Dual/Joint/Adjunct Appointment
Associate Member, Division of Medical Physics Program, GSBS, Houston, TX
Research Interests
Research Interests
Education & Training
Degree-Granting Education
1991 | University of Michigan, Ann Arbor, MI, USA, PHD, Electrical Engineering and Computer Science |
1985 | National Tsing-Hua University, Hsin-Chu, TWN, MS, Electrical Engineering |
1983 | National Tsing-Hua University, Hsin-Chu, TWN, BS, Electrical Engineering |
Postgraduate Training
1991-1994 | Postdoctoral Fellowship, Nuclear Medicine, University of Massachusetts Medical Center, Worcester, MA |
Selected Publications
Peer-Reviewed Articles
- McGovern SL, Luo D, Johnson J, Nguyen K, Li J, McAleer MF, Yeboa D, Grosshans DR, Ghia AJ, Chung C, Bishop AJ, Song J, Thall PF, Brown PD, Mahajan A. A Prospective Study of Conventionally Fractionated Dose Constraints for Re-Irradiation of Primary Brain Tumors in Adults. Practical Radiation Oncology 13(3):231-238, 2023. e-Pub 2022. PMID: 36596356.
- Pan T, Thomas MA, Luo D. Data-driven gated CT: An automated respiratory gating method to enable data-driven gated PET/CT. Medical Physics 49(6):3597-3611. e-Pub 2022. PMID: 35324002.
- Xu Q, Kubicek G, Mulvihill D, Goldman W, Eastwick G, Turtz A, Fan J, Luo D. Evaluating the Impact of Prescription Isodose Line (IDL) on Plan Quality Using Gamma Knife Inverse Planning. J Appl Clin Med Phys 22(9):289-297, 2021. e-Pub 2021. PMID: 34402582.
- Thrower SL, Al Feghali KA, Luo D, Paddick I, Hou P, Briere T, Li J, McAleer MF, McGovern SL, Woodhouse KD, Yeboa DN, Brock KK, Chung C. The Effect of Slice Thickness on Contours of Brain Metastases for Stereotactic Radiosurgery. Advances in Radiation Oncology 6(4):100708. e-Pub 2021. PMID: 34124413.
- Pan T, Lu Y, Thomas MA, Liao Z, Luo D. New Data-Driven Gated PET/CT Free of Misregistration Artifacts. Int J Radiat Oncol Biol Phys 109(5):1638-1646. e-Pub 2020. PMID: 33186619.
- Xu Q, Kubicek G, Mulvihill D, Eastwick G, Goldman H, Turtz AR, Fan J, Luo D. Tuning-Target-Guided Inverse Planning of Brain Tumors with Abutting Organs at Risk during Gamma Knife Stereotactic Radiosurgery. Cureus 12(8):e9585, 2020. PMID: 32923191.
- Han EY, Diagaradjane, P, Luo D, Ding Y, Kalaitzakis G, Zoros E, Zourari K, Boursianis T, Pappas E, Wen Z, Wang J, Briere TM. Validation of PTV margin for Gamma Knife Icon frameless treatment using a PseudoPatient® Prime anthropomorphic phantom. J Appl Clin Med Phys 21(9):278-285. e-Pub 2020. PMID: 32786141.
- Xu Q, Luo D, Mulvihill D, Goldman W, Turtz A, Kubicek GJ. Dosimetric Comparison of Inverse and Forward Planning for Gamma Knife Stereotactic Radiosurgery of Brain Metastases. Medical Dosimetry 45(4):317-320. e-Pub 2020. PMID: 32522429.
- Baltz GC, Briere T, Luo D, Howell R, Krafft S, Han EY. 3D-Printed Headrest for Frameless Gamma Knife Radiosurgery: Design and Validation. J Appl Clin Med Phys 21(9):6-15, 2020. PMID: 32603542.
- Luo D, Han EY, Wen Z, Mackin DS, Krafft SP, Li J, Wang X, Briere TM. Technical Note: Use of uniform shots for robust planning of mask-based treatment in Gamma Knife Icon. Physica Medica 73:135-157, 2020. e-Pub 2020. PMID: 32361402.
- Pan T, Hasegawa A, Luo D, Wu CC, Vikram R. Technical Note: Impact on central frequency and noise magnitude ratios by advanced CT image reconstruction techniques. Med Phys 47(2):480-487, 2020. e-Pub 2019. PMID: 31778233.
- Pan EY, Luo D, (Rozner MA), Pan T. Brief Report: Potential effects of low-dose average CT on cardiac implantable electronic devices. J Nucl Cardiol 26(4):1161-1165, 2019. e-Pub 2018. PMID: 29344923.
- Han EY, Luo D, Kim JO, Tharp K, Wen Z, Briere TM. Dosimetric validation of the Gamma Knife® IconTM plan adaptation and high-definition motion management system with a motorized anthropomorphic head phantom. Jour. of Radiosurgery and SBRT 6(3):217-226, 2019. PMID: 31998542.
- Jensen GL, Wu H, Luo D, Ho JC, Allen PK, Briere TM, Brown PD, Li J. Use of three pins in Gamma Knife stereotactic radiosurgery for brain metastases. Jour. of Radiosurgery and SBRT 6(3):209-216, 2019. PMID: 31998541.
- Wang X, Yang J, Zhao Z, Luo D, Court L, Zhang Y, Weksberg D, Brown PD, Li J, Ghia AJ. Dosimetric impact of esophagus motion in single fraction spine stereotactic body radiotherapy. Phys Med Biol 64(11):115010, 2019. e-Pub 2019. PMID: 31018191.
- Wang H, Yang JN, Zhang X, Li J, Frank SJ, Zhao Z, Luo D, Zhu X, Wang C, Tung S, Garden AS, Rosenthal DI, Fuller CD, Gunn GB, Ghia AJ, Reddy JP, Raza SM, Monte FD, Chambers MS, Brown PD, Su S, Phan J. Treatment-Plan Comparison of Three Advanced Radiation Treatment Modalities for Fractionated Stereotactic Radiotherapy to the Head and Neck. Int. J. Medical Physics, Clinical Engineering and Radiation Oncology 8(2):106-120, 2019.
- Han EY, Wang H, Luo D, Li J, Wang X. Dosimetric comparison of fractionated radiosurgery plans using frameless Gamma Knife ICON and CyberKnife systems with linear accelerator-based radiosurgery plans for multiple large brain metastases. J Neurosurg 132(5):1473-1479. e-Pub 2019. PMID: 30952125.
- Phan J, Pollard C, Brown PD, Guha-Thakurta N, Garden AS, Rosenthal DI, Fuller CD, Frank SJ, Gunn GB, Morrison WH, Ho JC, Li J, Ghia AJ, Yang JN, Luo D, Wang HC, Su SY, Raza SM, Gidley PW, Hanna EY, DeMonte F. Stereotactic radiosurgery for trigeminal pain secondary to recurrent malignant skull base tumors. Journal of Neurosurgery 130(3):1-10, 2018. PMID: 29701557.
- Wang X, Zhao Z, Luo D, Yang JN, Yang J, Chang EL, Brown PD, Li J, McAleer MF, Ghia AJ. Submillimeter alignment of more than three contiguous vertebrae in spinal SRS/SBRT with 6-degree couch. J Appl Clin Med Phys 18(5):225-236, 2017. e-Pub 2017. PMID: 28786235.
- Pan T, Martin RM, Luo D. New prospective 4D-CT for mitigating the effects of irregular respiratory motion. Phys Med Biol 62(15):N350-N361, 2017. e-Pub 2017. PMID: 28715346.
- Ho JC, Luo D, Guha-Thakurta N, Ferguson SD, Ghia AJ, Yang JN, Brown PD, Voong KR. Gamma Knife Stereotactic Radiosurgery for Brain Metastases Using Only 3 Pins. Neurosurgery 78(6):877-82, 2016. e-Pub 2015. PMID: 26488329.
- Wang H, Wang C, Tung S, Dimmitt AW, Wong PF, Edson MA, Garden AS, Rosenthal DI, Fuller CD, Gunn GB, Takiar V, Wang XA, Luo D, Yang JN, Wong J, Phan J. Improved setup and positioning accuracy using a three-point customized cushion/mask/bite-block immobilization system for stereotactic reirradiation of head and neck cancer. J Appl Clin Med Phys 17(3):6038, 2016. e-Pub 2016. PMID: 27167275.
- Wang X, Ghia AJ, Zhao Z, Yang J, Luo D, Briere TM, Pino R, Li J, Mcaleer MF, Weksberg DC, Chang EL, Brown PD, Yang JN. Prospective evaluation of target and spinal cord motion and dosimetric changes with respiration in spinal stereotactic body radiation therapy utilizing 4-D CT. J Radiosurgery and SBRT 4(3):191-201, 2016.
- Voong KR, Farnia B, Wang Q, Luo D, McAleer MF, Rao G, Guha-Thakurta N, Likhacheva A, Ghia AJ, Brown PD, Li J. Gamma knife stereotactic radiosurgery in the treatment of brainstem metastases: The MD Anderson experience. Neurooncol Pract 2(1):40-47, 2015. e-Pub 2015. PMID: 26034640.
- Riegel AC, Bucci MK, Mawlawi OR, Ahmad M, Luo D, Chandler A, Pan T. Defining internal target volume using positron emission tomography for radiation therapy planning of moving lung tumors. J Appl Clin Med Phys 15(1):279-289. e-Pub 2014. PMID: 24423860.
- Faught AM, Kry SF, Luo D, Molineu A, Bellezza D, Gerber RL, Davidson SE, Bosch W, Drzymala RE, Galvin J, Timmerman R, Sheehan J, Gillin MT, Ibbott GS, Followill DS. Development of a modified head and neck quality assurance phantom for use in stereotactic radiosurgery trials. J Appl Clin Med Phys 14(4):4313, 2013. PMID: 23835394.
- Pan T, Riegel AC, Ahmad MU, Sun X, Chang JY, Luo D. New weighted maximum-intensity-projection images from cine CT for delineation of the lung tumor plus motion. Med Phys 40(6):061901, 2013. PMID: 23718592.
- Likhacheva A, Pinnix CC, Parikh NR, Allen PK, McAleer MF, Chiu MS, Sulman EP, Mahajan A, Guha-Thakurta N, Prabhu SS, Cahill DP, Luo D, Shiu AS, Brown PD, Chang EL. Predictors of Survival in Contemporary Practice After Initial Radiosurgery for Brain Metastases. Int J Radiat Oncol Biol Phys 85(3):656-61, 2013. e-Pub 2012. PMID: 22898384.
- Likhacheva A, Pinnix CC, Parikh N, Allen PK, Guha-Thakurta N, McAleer M, Sulman EP, Mahajan A, Shiu A, Luo D, Chiu M, Brown PD, Prabhu SS, Chang EL. Validation of Recursive Partitioning Analysis and Diagnosis-Specific Graded Prognostic Assessment in patients treated initially with radiosurgery alone. J Neurosurg 117 Suppl:38-44, 2012. PMID: 23205787.
- Weksberg DC, Palmer MB, Vu KN, Rebueno NC, Sharp HJ, Luo D, Yang JN, Shiu AS, Rhines LD, McAleer MF, Brown PD, Chang EL. Generalizable Class Solutions for Treatment Planning of Spinal Stereotactic Body Radiation Therapy. Int J Radiat Oncol Biol Phys 84(3):847-53, 2012. e-Pub 2012. PMID: 22445000.
- Pulliam KB, Howell RM, Followill D, Luo D, White RA, Kry SF. The clinical impact of the couch top and rails on IMRT and arc therapy. Phys Med Biol 56(23):7435-47, 2011. e-Pub 2011. PMID: 22056949.
- Du W, Yang J, Luo D, Martel M. A simple method to quantify the coincidence between portal image graticules and radiation field centers or radiation isocenter. Med Phys 37(5):2256-63, 2010. PMID: 20527559.
- Riegel AC, Bucci MK, Mawlawi O, Johnson V, Ahmad M, Sun X, Luo D, Chandler A, Pan T. Target definition of moving lung tumors in positron emission tomography: Correlation of optimal activity concentration thresholds with object size, motion extent, and source-to-background ratio. Medical Physics 37(4):1742-52, 2010. PMID: 20443495.
- McCurdy M, McAleer MF, Wei W, Ezhil M, Johnson V, Khan M, Baker J, Luo D, Ajani J, Guerrero T. Induction and Concurrent Taxanes Enhance both the Pulmonary Metabolic Radiation Response and the Radiation Pneumonitis Response in Patients with Esophagus Cancer. Int J Radiat Oncol Biol Phys 76(3):816-823, 2010. e-Pub 2009. PMID: 19525073.
- Du W, Yang JN, Chang EL, Luo D, McAleer MF, Shiu A, Martel MK. A Quality Assurance Procedure to Evaluate Cone-beam CT Image Center Congruence with the Radiation Isocenter of a Linear Accelerator. J Appl Clin Med Phys 11(4):3297, 2010. e-Pub 2010. PMID: 21081890.
- Chi PC, Mawlawi O, Luo D, Liao Z, Macapinlac HA, Pan T. Effects of respiration-averaged computed tomography on positron emission tomography/computed tomography quantification and its potential impact on gross tumor volume delineation. Int J Radiat Oncol Biol Phys 71(3):890-9, 2008. PMID: 18514781.
- Hart JP, McCurdy MR, Ezhil M, Wei W, Khan M, Luo D, Munden RF, Johnson VE, Guerrero TM. Radiation pneumonitis: correlation of toxicity with pulmonary metabolic radiation response. Int J Radiat Oncol Biol Phys 71(4):967-71, 2008. e-Pub 2008. PMID: 18495373.
- Pan T, Sun X, Luo D. Improvement of the cine-CT based 4D-CT imaging. Med Phys 34(11):4499-503, 2007. PMID: 18072515.
- Guerrero T, Johnson V, Hart J, Pan T, Khan M, Luo D, Liao Z, Ajani J, Stevens C, Komaki R. Radiation pneumonitis: local dose versus [18F]-fluorodeoxyglucose uptake response in irradiated lung. Int J Radiat Oncol Biol Phys 68(4):1030-5, 2007. e-Pub 2007. PMID: 17398033.
- Chi PC, Mawlawi O, Nehmeh SA, Erdi YE, Balter PA, Luo D, Mohan R, Pan T. Design of respiration averaged CT for attenuation correction of the PET data from PET/CT. Med Phys 34(6):2039-2047, 2007. PMID: 17654907.
- Liu HH, Balter P, Tutt T, Choi B, Zhang J, Wang C, Chi M, Luo D, Pan T, Hunjan S, Starkschall G, Rosen I, Prado K, Liao Z, Chang J, Komaki R, Cox JD, Mohan R, Dong L. Assessing Respiration-Induced Tumor Motion and Internal Target Volume Using Four-Dimensional Computed Tomography for Radiotherapy of Lung Cancer. Int J Radiat Oncol Biol Phys 68(2):531-540, 2007. e-Pub 2007. PMID: 17398035.
- Starkschall G, Desai N, Balter P, Prado K, Luo D, Cody D, Pan T. Quantitative assessment of four-dimensional computed tomography image acquisition quality. J Appl Clin Med Phys 8(3):2362, 2007. PMID: 17712299.
- Pan T, Mawlawi O, Luo D, Liu HH, Chi PC, Mar MV, Gladish G, Truong M, Erasmus J, Jr, Liao Z, Macapinlac HA. Attenuation correction of PET cardiac data with low-dose average CT in PET/CT. Med Phys 33(10):3931-8, 2006. PMID: 17089855.
- Chi PC, Balter P, Luo D, Mohan R, Pan T. Relation of external surface to internal tumor motion studied with cine CT. Med Phys 33(9):3116-3123, 2006. PMID: 17022203.
- Pan T, Mawlawi O, Nehmeh SA, Erdi YE, Luo D, Liu HH, Castillo R, Mohan R, Liao Z, Macapinlac HA. Attenuation correction of PET images with respiration-averaged CT images in PET/CT. J Nucl Med 46(9):1481-1487, 2005. PMID: 16157531.
- Pan TS, Luo DS, Kohli V, King MA. Influence of OSEM, elliptical orbits and background activity on SPECT 3D resolution recovery. Phys Med Biol 42(12):2517-29, 1997. PMID: 9434304.
- King MA, Pan TS, Luo DS. An Investigation of Aliasing with Gaussian Diffusion Modeling of SPECT System Spatial Resolution. IEEE Trans. Nuclear Science 44(3):1375-80, 1997.
- Luo D-S, King MA, Morgan HT, Pan T-S, Xia W, Pretorius PH, Case JA. Investigations into Possible Causes of Hot Inferior Wall Artifacts in Attenuation Corrected Cardiac Perfusion Images. IEEE Trans. Nuclear Science 44(3):1146-53, 1997.
- Xia W, Glick SJ, Pan TS, Soares EJ, Luo D-S. Region of Interest Evaluation of SPECT Image Reconstruction Methods Using a Realistic Brain Phantom. IEEE Trans. Nuclear Science 44(3):1336-41, 1997.
- Pan TS, King MA, Luo DS, Dahlberg ST, Villegas BJ. Estimation of attenuation maps from scatter and photopeak window single photon-emission computed tomographic images of technetium 99m-labeled sestamibi. J Nucl Cardiol 4(1 Pt 1):42-51, 1997. PMID: 9138839.
- Luo DS, King MA, Pan T-S, Xia W. Evaluation of the Effects of Patient Arm Attenuation in SPECT Cardiac Perfusion Imaging. IEEE Trans. Nuclear Science 43(6):3291-99, 1996.
- Pretorius PH, King MA, Glick SJ, Pan TS, Luo DS. Reducing the Effect of Non-Stationary Resolution on Activity Quantitation with the Frequency Distance Relationship in SPECT. IEEE Trans Nuclear Science 43(6):3335-41, 1996.
- King MA, Luo D, Dahlberg ST, Villegas BJ, Penney BC, Morgan HT. Transmission imaging of large attenuators using a slant hole collimator on a three-headed SPECT system. Med Phys 23(2):263-72, 1996. PMID: 8668108.
- Luo DS, Yagle AE. A Kalman Filtering Approach to Stochastic Global and Region-of-Interest Tomography. IEEE Trans Image Process 5(3):471-9, 1996. PMID: 18285132.
- Case JA, Pan TS, King MA, Luo DS, Penney BC, Rabin MSZ. Reduction of Truncation Artifacts in Fan Beam Transmission Imaging Using a Spatially Varying Gamma Prior. IEEE Trans. Nuclear Science 42(6):2260-65, 1995.
- Pan TS, King MA, Penney BC, Rajeevan N, Luo DS, Case JA. Reduction of Truncation Artifacts in Fan Beam Transmission by Using Parallel Beam Emission Data. IEEE Trans. Nuclear Science 42(4):1310-20, 1995.
- Glick SJ, deVries DJ, Luo DS, King MA. Distance-Dependent Restoration Filtering of Dual Photopeak Window Scatter Compensated SPECT Images. IEEE Trans. Nuclear Science 41(6):2787-92, 1994.
- Luo DS, King MA, Glick SJ. Local Geometry Variable Conductance Diffusion for Post-reconstruction Filtering. IEEE Trans. Nuclear Science 41(6):2800-6, 1994.
Other Articles
- Granfors PR, Albagli D, Tkaczyk EJ, Aufrichtig R, Netel H, Brunst G, Boudry JM, Luo DS Performance of a Flat-Panel Cardiac Detector. Proc. of SPIE Medical Imaging, Physics of Medical Imaging 4320:77-86, 2001.
Abstracts
- Luo D, Han E, Wang X, Briere TM. Use of non-composite shots for robust planning in Gamma Knife Icon mask-based treatment. ISRS 2019 Oral Presentation:B32-5 # 17882, 2019.
- Han EY, Luo D, Kim JO, Tharp K, Wen Z, Briere TM. End-To-End Test of the Gamma Knife Icon Plan Adaptation and High Definition Motion Management System Using a Motorized Anthropomorphic Head Phantom. Medical Physics 46(6):e202, 2019.
- Luo D, Guha-Thakurta N, Wang X, Han E, Wang H, Li J, Pan T. Metal artifact reduction with Dual Energy CT for Gamma Knife Radiosurgery in pacemaker patients. Journal of Radiosurgery and SBRT 5(Supplement 1):44, 2017.
- Luo D, Mawlawi O, Vicic M, Balter PA, Martel MK, Pan T. A New Clinical Utility for Tumor Delineation using SUV of PET images in Treatment Planning. ITART June 21-22, 2010:PO-QI-5, 2010.
Grant & Contract Support
Title: | A Phase ll Study to Test Correlation of a Radiation Pneumonitis Imaging Biomarker with Clinical Endpoints |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Optimization of MRI Image Alignment for Spinal SBRT Treatment |
Funding Source: | Elekta |
Role: | Co-Investigator |
Patient Reviews
CV information above last modified June 26, 2024