Ellen Manzullo, M.D., F.A.C.P.
Department of General Internal Medicine, Division of Internal Medicine
About Dr. Manzullo
Ellen F. Manzullo, MD, FACP is a Professor in the Department of General Internal Medicine. She serves as the Deputy Division Head (Clinical) of Internal Medicine and the Deputy Department Chair (Clinical) of General Internal Medicine. Dr. Manzullo is also the Executive Director for Internal Medicine in the MD Anderson Cancer Network. Dr. Manzullo joined the faculty of MD Anderson Cancer Center upon completion of her internal medicine residency in 1989. As a general internist she has focused on the delivery of high quality internal medicine care to cancer patients and survivors.
Throughout her career, Dr. Manzullo has been committed to educational activities. Most recently she was instrumental in the development of the Baylor/MD Anderson Cancer Center Internal Medicine Residency Program which launched in 2015 and has been supported by an expansion grant from the Texas Higher Education Coordinating Board. The goal of this program is to train the next generation of leaders in the internal medicine care of the cancer patient and survivor. Dr. Manzullo has lectured extensively to a variety of audiences including patients and she has also chaired or served on the planning committee of many conferences. Her publications throughout her career have been focused on oncologic emergencies, perioperative medicine, and cancer related fatigue. Dr. Manzullo's excellence has been recognized by her being named a US News Top Doctor, Castle Connolly Top Doctor, and America's Top Physician. In 2017, she was named a Castle Connolly Exceptional Woman in Medicine.
Present Title & Affiliation
Primary Appointment
Professor of Medicine (NTCA), Department of General Internal Medicine, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 1986 | The University of Texas Medical School at Houston, Houston, TX, USA, MD, Doctor of Medicine |
| 1982 | St. Mary's University, San Antonio, TX, USA, Bachelor of Science, Summa Cum Laude |
Postgraduate Training
| 2014-2015 | Course, Graduate Certificate in Health Care Management, Rice University, Jones Graduate School of Business, Houston, TX |
| 2005-2006 | Course, Faculty Leadership Academy, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 2005-2005 | Course, Mini-Advanced Training Program in Health Care Delivery, Intermountain Health Care Institute, Salt Lake City, UT |
| 1999-2000 | Course, Executive Excellence Program, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 1987-1989 | Clinical Residency, The University of Texas Medical School, Houston, TX |
| 1986-1987 | Clinical Internship, The University of Texas Medical School, Houston, TX |
Board Certifications
| 1990 | American Board of Internal Medicine |
Experience & Service
Academic Appointments
Assistant Internist & Instructor in Medicine (NTCA), The University of Texas M. D. Anderson Cancer Center, Houston, TX, 1989 - 1991
Administrative Appointments/Responsibilities
Executive Director, Internal Medicine, Department of Cancer Network, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - Present
Deputy Division Head (Clinical), The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - Present
Deputy Department Chair, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2005 - Present
Associate Medical Director, Ambulatory Treatment Center, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 1997 - 2016
Institutional Committee Activities
Reviewer, 2020 Distinguished Faculty Mentor Awards Committee, 2019 - Present
Member, Cancer Network Adjunct Appointment Committee, 2019 - 2022
Member, Division of Internal Medicine Education Task Force, 2019 - 2020
Member, Survivorship Operational Priority Committee, 2019 - 2020
Member, Educational Operational Task Force, Clinical Subgroup, 2017 - 2018
Member, Geographic Expansion Strategy Task Force, National Subgroup, 2017 - 2017
Member, Faculty Mentoring Advisory Committee, 2016 - 2019
Distinguished Clinical Faculty Mentor Award, Selection Committee 2016 Provost's, 2016 - Present
Member, Regional Care Faculty Contracts Committee, 2014 - 2016
Member, Medical Quality Planning Committee, 2014 - 2019
Member, Clinical Faculty Review Committee, 2014 - 2017
Alternate Member (nominated by Dr. DePinho), Negotiated Rulemaking Committee on Resident Physician Expansion Program, Texas Higher Education Coordinating Board, 2014 - 2014
Chair, PRS Physician Compensation & Benefit Committee, 2013 - Present
Ex-Officio Member, PRS Executive Council, 2013 - Present
Immediate Past Chair, Executive Committee of Medical Staff, 2012 - 2015
Selection Committee Member, Ethel Fleming Arceneaux Outstanding Nurse Oncologist Award, 2011 - 2012
Member, Survivorship Research Advisory Workgroup, 2010 - Present
Selection Committee Member, Ethel Fleming Arceneaux Outstanding Nurse Oncologist Award, 2010 - 2011
Chair, Executive Committee Medical Staff, 2009 - 2012
Member, President's Advisory Board, 2009 - 2011
Member, Cancer Survivorship Education Committee, 2009 - Present
Member, Search Committee for Chair of Psychiatry, The University of Texas M. D. Anderson Cancer Center and Baylor College of Medicine, 2008 - 2009
Member, Division of Internal Medicine Quality Council, 2007 - 2009
Chair-Elect, Executive Committee Medical Staff, 2006 - 2009
Member, American College of Surgeons (ACOS) - Commission on Cancer Site Visit Committee, 2006 - 2006
Member, Search Committee for Chief of Clinical Ethics Section, 2006 - 2006
Chairman, Clinical Faculty Review Committee, 2005 - 2007
At-Large Member, Executive Committee Medical Staff, 2004 - 2006
Member, Clinical Faculty Review Committee, 2004 - 2005
Chairman, Medical Record Committee, 2003 - 2007
Member, Patient Safety Committee, 2003 - 2014
Member, Ethics Committee, 2002 - 2005
Member, Executive Committee of Medical Staff (at Large Member), 2000 - 2003
Chairman, M. D. Anderson Physician Network Quality Council, 1999 - 2010
Member, Quality Council, 1999 - 2009
Member, Subcommittee for Selection of Faculty Achievement Awards in Patient Care, 1999 - 2000
Member, Executive Committee Faculty Senate, 1999 - 2001
Member, Institutional Risk Management Committee, 1998 - 2000
Vice-Chairman, Medical Records Committee, 1997 - 2003
Member, Faculty Senate, 1997 - 2001
Member, M. D. Anderson Physician Network Quality Improvement Committee, 1997 - 1999
Member, Quality Improvement Committee, 1996 - 1999
Member, Institutional Risk Management Committee, 1994 - 1996
Member, Medical Records Committee, 1992 - 1997
Honors & Awards
| 2018 | Castle Connolly Top Doctor |
| 2017 | Castle Connolly Exceptional Women in Medicine |
| 2017 | President's Award for Faculty Excellence in Network Development, The University of Texas M.D. Anderson Cancer Center |
| 2017 | MD Anderson Distinguished Clinical Faculty Mentoring Nominee, The University of Texas M.D. Anderson Cancer Center |
| 2017 | America's Most Honored Professionals - Top 5% |
| 2017 | Castle Connolly Top Doctor |
| 2016 | Castle Connolly Top Doctor |
| 2016 | Multi-year Appointment Award, The University of Texas M. D. Anderson Center |
| 2016 | Samuel J. Hassenbusch III MD, PhD PRS Leadership and Institutional Service Award, The University of Texas M.D. Anderson Cancer Center |
| 2015 | Castle Connolly Top Doctor |
| 2015 | Top Reviewer, Annals of Internal Medicine |
| 2014 | Doctor of Excellence, Board of the Leaders in Healthcare Network |
| 2014 | Castle Connolly Top Doctor |
| 2014 | America's Top Physician |
| 2014 | Finalist, Julie & Ben Rogers Award for Excellence in Patient Care |
| 2013 | US News Top Doctor |
| 2013 | Castle Connolly Top Doctor |
| 2013 | Multi-year Appointment Award, The University of Texas M. D. Anderson Center |
| 2012 | US News Top Doctor |
| 2012 | Castle Connolly Top Doctor |
| 2010 | Multi-year Appointment Award, The University of Texas M. D. Anderson Center |
| 2008 | Fellow, Clinical Safety and Effectiveness, The University of Texas M. D. Anderson Cancer Center |
| 2007 | Multi-year Appointment Award, The University of Texas M. D. Anderson Center |
| 2004 | Multi-year Appointment Award, The University of Texas M. D. Anderson Center |
| 2003 | General Internal Medicine Preceptorship Award 2012, American College of Physicians, Texas Chapter |
| 2000 | Physician's Recognition Award, American Medical Association |
| 1995 | Fellow, American College of Physicians |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Lacourt TE, Vichaya EG, Escalante C, Manzullo EF, Gunn B, Hess KR, Heijnen CJ, Dantzer R. An effort expenditure perspective on cancer-related fatigue. Psychoneuroendocrinology 96:109-117, 2018. e-Pub 2018. PMID: 29929087.
- Balachandran DD, Faiz SA, Bashoura L, Manzullo EF. Cancer-related fatigue presenting with excessive daytime sleepiness. SAGE Open Med Case Rep 5:2050313X17748865, 2017. e-Pub 2017. PMID: 29318018.
- Yennurajalingam S, Reddy A, Tannir NM, Chisholm GB, Lee RT, Lopez G, Escalante CP, Manzullo EF, Frisbee Hume S, Williams JL, Cohen L, Bruera E. High-Dose Asian Ginseng (Panax Ginseng) for Cancer-Related Fatigue: A Preliminary Report. Integr Cancer Ther 14(5):419-27, 2015. e-Pub 2015. PMID: 25873296.
- Carmen P. Escalante, MD; Christina Meyers, PhD; James M. Reuben, PhD; Xuemei Wang, MS; Wei Qiao, MS; Ellen F. Manzullo, MD; Ricardo H. Alvarez, MD; Phuong Khanh Morrow, MD; Ana M. Gonzalez-Angulo, MD; Xin Shelley Wang, MD; Tito mendoza, PhD; Wenli Liu, MD; Holly Holmes, MD; Jessica Hwang, MD; Katerine Pisters, MD; Michael Overman, MD; Charles Cleeland, PhD. A Randomized, Double-Blind, Two-Period, Placebo-Controlled Crossover Trial of Sustained Release Methylphenidate in the Treatment of Fatigue in Cancer Patients. Cancer Journal 20(1):8-14, 2014. PMID: 24445757.
- Escalante CP, Kallen MA, Valdres RU, Morrow PK, Manzullo EF. Outcomes of a Cancer-Related Fatigue Clinic in a Comprehensive Cancer Center. J Pain Symptom Manage 39(4):691-701, 2010. e-Pub 2010. PMID: 20226622.
- Rolston KV, Frisbee-Hume SE, Patel S, Manzullo EF, Benjamin RS. Oral moxifloxacin for outpatient treatment of low-risk, febrile neutropenic patients. Support Care Cancer 18(18):89-94, 2010. e-Pub 2009. PMID: 19387695.
- Escalante CP, Manzullo EF. Cancer-Related Fatigue: The Approach and Treatment. J Gen Intern Med 24(2):412-416, 1525-1497, 2009. e-Pub 2009. PMID: 19838841.
- Escalante CP, Manzullo EF, Lam TP, Ensor JE, Valdres RU, Wang XS. Fatigue and its Risk Factors in Cancer Patients Who Seek Emergency Care. J Pain Symptom Manage 36(4):358-66, 2008. e-Pub 2008. PMID: 18411011.
- Rolston KV, Manzullo EF, Elting LS, Frisbee-Hume SE, McMahon L, Theriault RL, Patel S, Benjamin RS. Once Daily, Oral, Outpatient Quinolone Monotherapy for Low-risk Cancer Patients with Fever and Neutropenia: A Pilot Study of 40 Patients Based on Validated Risk-prediction Rules. Cancer Vol. 1, No. 106(11)(11):2489-94, 2006. PMID: 16628654.
- Escalante CP, Weiser MA, Manzullo E, Benjamin R, Rivera E, Lam T, Ho V, Valdres R, Lee EL, Badrina N, Fernandez S, DeJesus Y, Rolston K. Outcomes of Treatment Pathways in Outpatient Treatment of Low Risk Febrile Neutropenic Cancer Patients. Support Care Cancer Vol. 12(9):657-62, 2004. PMID: 15185134.
- Elting LS, Cooksley C, Chambers M, Cantor SB, Manzullo E, Rubenstein EB. The Burdens of Cancer Therapy: Clinical and Economic Outcomes of Chemotherapy-Induced Mucositis. Cancer Vol. 98, No. 7(7):1531-9, 2003. PMID: 14508842.
- Escalante CP, Manzullo E, Valdres R. A Cancer-Related Fatigue Clinic: Opportunities and Challenges. J Natl Compr Canc Netw Vol. 1, No. 3(3):333-343, 2003. PMID: 19761068.
- Manzullo E, Liu W, Escalante C. Treatment of Cancer-Related Fatigue: An Update. Expert Review of Anticancer Therapy Vol. 3, No. 1:99-106, 2003.
- Manzullo E, Escalante C, Weiser MA, Freedman R, Forman A. Case Report: An Elderly Woman with an Ovarian Mass and Myasthenia Gravis. Resident and Staff Physician:55-61, 2001.
- Escalante CP, Martin CG, Elting LS, Price KJ, Manzullo EF, Weiser MA, Harle TS, Cantor SB, Rubenstein EB. Identifying Risk Factors for Imminent Death in Cancer Patients with Acute Dyspnea. Journal of Pain and Symptom Management Vol. 20, No. 5:318-25, 2000. PMID: 11068153.
Invited Articles
- Manzullo EF, Weed HG. Perioperative Issues in Patients with Cancer. Med Clin North Am Vol. 87(1):243-56, 2003. PMID: 12575893.
- Manzullo EF, Escalante CP. Research Into Fatigue. Hematol Oncol Clin North Am Vol. 16,(3):619-28, 2002. PMID: 12170571.
Manuals, Teaching Aids, Other Teaching Publications
- Manzullo EF, Balachandran. Lecture: Professional Oncology Education Taping on Survivorship: Cancer Related Fatigue and Sleep (Part i), 2010.
- Burman K, Manzullo E, Yeung SC. Perioperative Management of Hyperthyroid Patients. American College of Physician's PIER (Physicians' Information and Education Resource). Peer-Reviewed, 2006.
- Manzullo E, Yeung SC. Perioperative Management of Hypothyroid Patients. American College of Physician's PIER (Physicians' Information and Education Resource). Peer-Reviewed, 2005.
- Mundy S, Manzullo E, Escalante C. Medical Backgrounder on Cancer-Related Fatigue. Timely Topics in Medicine, 2003.
- . Chemotherapy and You: The University of Texas M. D. Anderson Cancer Center, 2000.
Other Articles
- Manzullo, EF Cancer Fatigue: Strategies to Help You Cope. Coping with Cancer, 2016.
- Manzullo, EF Fighting Fatigue. Coping with Cancer: 4, 2012.
- Manzullo, EF Fighting Fatigue. Coping with Cancer: 7:7, 2008.
Abstracts
- Sahai S, Porter A, Manzullo E, Andrabi T, Holmes L. Survey of Perioperative Beta-Blockade at a Comprehensive Cancer Center. IN Program/Proceedings of 2nd Annual Perioperative Medicine Summit Volume 73 E-Supplement 1, 2006.
- Sahai S, Wobb J, Manzullo E. The Internal Medicine Perioperative Assessment Center: An Innovation in the Perioperative Management of Medical Comorbidities at a Comprehensive Cancer Center. Cleveland Clinic Journal of Medicine 73 E-Supplement 1, 2006.
- Porter A, Sahai SK, Manzullo E, Andrabi T, Holmes L.. A Needs Assessment of Perioperative and Long-Term Beta-Blockade in Cancer Patients Undergoing Surgery. IN Program/Proceedings of The University of Texas M. D. Anderson Cancer Center, Division of Internal Medicine Research Retreat, Houston, TX, 2006.
Book Chapters
- Yeung SJ, Manzullo EF. In: Oncologic Emergencies, MD Anderson Manual of Medical Oncology. 3rd. McGraw-Hill Education: New York, 1073-1098, 2016.
- Escalante E, Manzullo EF. Fatigue. In: Advances in Cancer Survivorship Management (MD Anderson Cancer Care Series). 2015 Edition. Springer, 361-373, 2015.
- Balachandran DD, Fais S, Bashoura L, Manzullo EF. Cancer-Related Fatigue and Sleep Disorders. In: Sleep Medicine Clinics. 2, 229-35, 2013.
- Sahai SK, Manzullo EF. Cancer. In: Perioperative Medicine. 1st. Springer, 281-295, 2011.
- Escalante CP, Manzullo EF. Cancer-Related Fatigue. In: MD Anderson Manual of Psychosocial Oncology. Valentine/Duffy: India, 139-148, 2010.
- Escalante CP, Manzullo EF, Weiss M. Oncologic Emergencies and Paraneoplastic Syndromes. In: Cancer Management: A Multidisciplinary Approach. The Oncology Group New York: New York, 2008.
- Chambers MS, Garden AS, Manzullo EF, Lemon JC, Martin JW. Xerostomia and Mucositis. In: Oral Cancer: Diagnosis, Management, and Rehabilitation. Thieme Medical Publishing: New York, 288-295, 2007.
- Escalante CP, Manzullo EF, Weiss M. Oncologic Emergencies and Paraneoplastic Sndromes. In: Cancer Management: A Multidisciplinary Approach. 10th. CPM Medica: Darien, CT, 979-1002, 2007.
- Lance C, Manzullo EF, Weed HG. Cancer. In: Perioperative Medicine: Just The Facts. McGraw Hill: New York, New York, 181-185, 2006.
- Mundy S, Manzullo E. Oncologic Emergencies. In: The M. D. Anderson Manual of Medical Oncology. McGraw Hill: New York, New York, 1011-1041, 2006.
- Escalante CP, Manzullo EF, Weiss M, Bonin SR. Oncologic Emergencies and Paraneoplastic Syndromes. In: Cancer Management: A Multidisciplinary Approach. 10th. The Oncology Group: New York, New York, 2006.
- Manzullo EF, Hwang J, Weed H. Preoperative Management of Patients with Cancer. In: Up to Date, 2003.
- Pentz RD, Flamm AL, Manzullo EF. Ethical Emergency Care. In: Oncologic Emergencies. B.C. Decker Inc, 13-24, 2002.
- Escalante CP, Hwang JP, Grover T, Rajagopal A, Den GE, Lazo-Diaz G, Forman AD, Manzullo EF, Gao S, Apisarnthanarax N, Duvic M. Major Presenting Symptoms. In: Oncologic Emergencies. B.C. Decker Inc, 25-60, 2002.
- Manzullo EF, Rhines L, Forman A. Neurologic Emergencies. In: Oncologic Emergencies. B.C. Decker Inc, 270-280, 2002.
- Manzullo EF, Welsh GA, Ross DS. Nonthyroid surgery in the patient with thyroid disease. In: Up to Date, 2001.
- Escalante CP, Manzullo EF, Gollamudi SV, Bonin SR. Oncologic emergencies and paraneoplastic syndromes. In: Cancer Management: A multidisciplinary Approach. PRR, Inc, 835-858, 2001.
- Welsh GA, Manzullo EF, Orth DN. The surgical patient taking corticosteroids. In: Up to Date, 2001.
Books (edited and written)
- Unknown. Oncologic Emergencies. In: MD Anderson Cancer Care Series. Ed(s) Manzullo EF, Gonzalez CE, Escalante CP, Yeung SJ. Springer: New York, 2016.
Patient Reviews
CV information above last modified August 27, 2024