Skip to Content

'
Farhad Danesh

Present Title & Affiliation

Primary Appointment

Professor, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Adjunct Professor of Pharmacology, Baylor College of Medicine, Houston, TX
Adjunct Professor of Medicine, Baylor College of Medicine, Houston, TX

Education & Training

Degree-Granting Education

1989 University of Alcala, Madrid, Spain, MD, Medicine

Postgraduate Training

7/1998-6/1999 Research Fellowship, Northwestern University, Chicago, IL
7/1996-6/1998 Nephrology Fellowship, Northwestern University, Chicago, IL
7/1993-6/1996 Internship/Residency, University of Chicago / Weiss Memorial Hospital, Chicago, IL
4/1991-3/1992 Research Fellowship, University of Toronto, Toronto, Canada

Experience/Service

Academic Appointments

Professor, Baylor College of Medicine, Houston, TX, 11/2012-present
Professor of Pharmacology, Baylor College of Medicine, Houston, TX, 11/2012-present
Associate Professor, Baylor College of Medicine, Houston, TX, 1/2008-11/2012

Professional Memberships

American Diabetes Association
Grant Review Committee, 2009-present
American Society of Nephrology
Grant Review Committee, 2008-present
Journal of American Society of Nephrology - JASN
Editorial Board, 8/2014-present
Kidney International
Editorial Board, 3/2012-present
National Institutes of Health - Pathobiology of Kidney Disease Study Section, Bethesda, MD
Standing Member, 2010-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Badal SS, Danesh FR. MicroRNAs and their applications in kidney diseases. Pediatr Nephrol. e-Pub 6/14/2014. PMID: 24928414.
2. Badal SS, Danesh FR. New insights into molecular mechanisms of diabetic kidney disease. Am J Kidney Dis 63(2 Suppl 2):S63-83, 2/2014. PMCID: PMC3932114.
3. Long J, Badal SS, Wang Y, Chang BH, Rodriguez A, Danesh FR. MicroRNA-22 is a Master Regulator of Bone Morphogenetic Protein-7/6 Homeostasis in the Kidney. J Biol Chem 288(51):36202-14, 12/20/2013. e-Pub 10/25/2013. PMCID: PMC3868735.
4. Badal SS, Danesh FR. Strategies to reverse endothelial dysfunction in diabetic nephropathy. Kidney Int 82(11):1151-4, 12/2012. PMCID: PMC3914716.
5. Wang W, Wang Y, Long J, Wang J, Haudek SB, Overbeek P, Chang BH, Schumacker PT, Danesh FR. Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. Cell Metab 15(2):186-200, 2/8/2012. PMCID: PMC3278719.
6. Badal SS, Danesh FR. Managing microvascular complications of diabetes with microRNAs. J Am Soc Nephrol 23(2):185-7, 2/2012. e-Pub 1/12/2012. PMCID: PMC3269171.
7. Long J, Wang Y, Wang W, Chang BH, Danesh FR. MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy. J Biol Chem 286(13):11837-48, 4/1/2011. e-Pub 2/10/2011. PMCID: PMC3064234.
8. Wang J, Wang Y, Long J, Chang BH, Wilson MH, Overbeek P, Danesh FR. Tamoxifen-inducible podocyte-specific iCre recombinase transgenic mouse provides a simple approach for modulation of podocytes in vivo. Genesis 48(7):446-51, 7/2010. PMCID: PMC3014324.
9. Kolavennu V, Zeng L, Peng H, Wang Y, Danesh FR. Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control. Diabetes 57(3):714-23, 3/2008. e-Pub 12/14/2007. PMID: 18083785.

Abstracts

1. Long J, Wang Y, Danesh FR. Identification of microRNA-93 as a novel regulator of vascular endothelial growth factr (VEGF) in hyperglycemic conditions. American Society of Nephrology Annual Meeting, Oral Presentation, 11/2010.
2. Long J, Wang Y, Wang W, Danesh FR. MicroRNA-29c targets sprouty1, promotes apoptosis and fibrosis, and its inhibition prevents progression of diabetic nephropathy. Anerican Society of Hephrology Annual Meeting, Oral Presentation, 11/2010.

Book Chapters

1. Danesh FR. Moleculary aspects of diabetic nephropathy. In: Molecular Pathology of Renal Diseases: Pathogenic, Diagonostic, and Therapeutic Implications, 2012.

Grant & Contract Support

Title: MicroRNAs in diabetic nephrolpathy
Funding Source: NIH/NIDDK
Role: Principal Investigator
Duration: 9/1/2011 - 8/31/2016
 
Title: Rho Kinases in diabetic nephropathy
Funding Source: NIH/NIDDK
Role: Principal Investigator
Duration: 2/1/2009 - 1/31/2019

Last updated: 9/24/2014