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Frederick F. Lang, Jr, MD, FACS

Present Title & Affiliation

Primary Appointment

Professor (tenure), Department of Neurosurgery, Division of Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX
Director of Clinical Research, Department of Neurosurgery, Division of Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Faculty Member, The University of Texas M. D. Anderson Cancer Center, Graduate School of Biomedical Sciences, Houston, TX
Adjunct Professor, Department of Neurosurgery, Baylor College of Medicine, Houston, TX

Office Address

The University of Texas M. D. Anderson Cancer Center
1515 Holcombe Blvd.
Department of Neurosurgery
Unit Number: 442
Houston, TX 77030
Room Number: FC7.2000
Phone: (713) 792-2400
Fax: (713) 794-4950

Education & Training

Degree-Granting Education

1988 Yale University School of Medicine, New Haven, CT, MD, Medicine
1984 Yale College, Yale University, New Haven, CT, BS, Biology

Postgraduate Training

7/1995-6/1996 Clinical Fellowship, Neurosurgical Oncology, Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center, Houston, TX
7/1993-7/1995 Clinical Residency, Chief Resident, Department of Neurosurgery, New York University Medical Center, New York, NY
7/1989-6/1993 Clinical Residency, Department of Neurosurgery, New York University Medical Center, New York, NY
6/1988-6/1989 Clinical Internship, General Surgery, New York University Medical Center, New York, NY

Board Certifications

2000 The American Board of Neurological Surgery

Honors and Awards

2009-present International Who's Who of Professionals
2009-present Who's Who Among Executives and Professionals Throughout the World
2007-present Global Directory of Who's Who
2004-present America's Top Doctors for Cancer
2003-present Best Doctors in America

Professional Memberships

American College of Surgeons
Fellow, 2001-present
Congress of Neurological Surgeons
Member, 1997-present
Harris County Medical Society
Member, 1997-present
Houston Neurological Society
Member, 1997-present
Society for Neuro-Oncology
Vice President, 2007-present
Society for Neuro-Oncology
Chairman, Education Day Annual Meeting, 2004-present

Selected Publications

Peer-Reviewed Original Research Articles
1. Williams BJ, Suki D, Fox BD, Maldaun MVC, Sawaya RE, Lang FF, Rao G. Stereotactic radiosurgery for metastatic brain tumors: a comprehensive review of complications. J Neurosurg. In Press. PMID: 19301968.
2. Tatsui CE, Lang FF, Gumin J, Suki D, Rhines LD. An orthotopic murine model of human spinal metastasis: histological and functional correlations. J Neurosurg Spine 10(6):501-512, June, 2009. PMID: 19558282.
3. Kim SS, McCutcheon IE, Suki D, Weinberg JS, Sawaya R, Lang FF, Ferson D, Heimberger AB, DeMonte F, Prabhu SS. Awake craniotomy for brain tumors near eloquent cortex: correlation of intraoperative cortical mapping with neurological outcomes in 309 consecutive patients. Neurosurgery 64(5):836-46, May, 2009. PMID: 19404147.
4. McCord A, Jamal M, Shankavaram U, Lang FF, Camphausen K, Tofilon P. Physiological oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro. Mol Cancer Res 7(4):489-97, Apr, 2009. PMID: 19372578.
5. Amano T, Nakamizo A, Mishra SK, Gumin J, Shinojima N, Sawaya R, Lang FF. Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes. J Neurooncol 92(3):357-71, May, 2009. PMID: 19357962.
6. Toms SA, Weil RJ, Gupta A, Boulis NM, Prayson R, Lang FF. Clinical problem solving: island intruder. Neurosurgery 62(4):920-8; discussion 928-9, 4/2008. PMID: 18496198.
7. Alonso MM, Jiang H, Yokoyama T, Xu J, Bekele NB, Lang FF, Kondo S, Gomez-Manzano C, Fueyo J. Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death. Mol Ther 16(3):487-93, Mar, 3/2008. PMID: 18253154.
8. Nakamizo A, Amano T, Zhang W, Zhang XQ, Ramdas L, Liu TJ, Bekele BN, Shono T, Sasaki T, Benedict WF, Sawaya R, Lang FF. Phosphorylation of Thr18 and Ser20 of p53 in Ad-p53-induced apoptosis. Neuro Oncol 10(3):275-291, Jun, 2008. PMID: 18443131.
9. Gilbert MR, Lang FF. Management of patients with low-grade gliomas. Neurol Clin 25(4):1073-88, Nov, 2007. PMID: 17964026.

Invited Articles
1. Gilbert MR, Lang FF. Should patients with anaplastic oligodendroglial tumors receive adjuvant chemotherapy. Nat Clin Pract Neurol 3(1):14-5, 1/2007.
2. Gilbert MR, Lang FF. Anaplastic oligodendroglial tumors: a tale of two trials. J Clin Oncol 24(18):2689-90, 6/2006.

Book Chapters
1. Chern JJ, Rao G, Lang FF. Medulloblastoma. In: Winn HR (ed). In: Youmans Neurological Surgery. 6th ed. W.B. Saunders Co: Philadelphia, PA. In Press.
2. Sawaya R, Bindal RK, Lang FF, Suki D. Metastatic Brain Tumors. In: Kaye AH, Laws ER, (eds). In: Brain Tumors: An Encyclopedic Approach. 3rd Edition. Elsevier: Philadelphia, PA. In Press.
3. Lang FF, Chang EL, Suki D, Wildrick DM, Sawaya R. Metastatic Brain Tumors. In: Winn HR, (ed). In: Youmans Neurological Surgery, 6th Edition. W. B. Saunders Co. Philadelphia, PA. In Press.
4. Lang FF, Sawaya R. Supratentorial cerebral metastases. In: Kaye AH, Black PM, (eds). In: Operative Neurosurgery. Churchill Livingstone: Edinburgh, Scotland. In Press.
5. Wu A, Lang FF. Surgery for insular gliomas. In: Mehta MP, Chang SM, Vogelbaum MA, Guha A (eds). In: Principles and practices of neuro-oncology: a multidisciplinary approach. Demos Medical Publishers: New York, NY. In Press.

Last updated: 8/18/2009