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Gabriel O. Sawakuchi, Ph.D

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Regular Faculty Member, Graduate School of Biomedical Sciences, The University of Texas, Houston, TX
Adjunct Professor, Physics, Carleton University, Ottawa, Ontario, Canada

Research Interests

The Sawakuchi Lab currently focuses on the study of of DNA repair response induced by radiation and to develop innovative radiation detection technologies for applications in radiation therapy and radiation biology research. Here you can find more information about my research.

Office Address

The University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd
Unit Number: 94
Houston, TX 77030
Room Number: B1.4580
Phone: 713-794-4034

Education & Training

Degree-Granting Education

2007 Oklahoma State University, Stillwater, OK, PHD, Physics
2003 University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil, MS, Physics
2001 University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil, BS, Physics


Academic Appointments

Assistant Professor, Physics, Carleton University, Ottawa, Ontario, Canada, 4/2010-1/2013

Other Appointments/Responsibilities

Visiting Scholar, Oklahoma State University, Stillwater, OK, 2/2003-6/2003

Honors and Awards

2012 Early Career Researcher Supplement Award, Natural Science and Engineering Research Council of Canada
2012 One of the 20 best referees for the Physics in Medicine and Biology Journal
2011 One of the 20 best referees for the Physics in Medicine and Biology Journal
2005 NASA Space Radiation Summer School Award, NASA
2004 International School on Radiation Effects in Solids Travel Award
2002-2003 Sao Paulo Research Foundation (FAPESP) Master of Science Scholarship
1999-2001 Sao Paulo Research Foundation (FAPESP) Undergraduate Scholarship

Selected Publications

Peer-Reviewed Original Research Articles

1. Granville DA, Sahoo N and Sawakuchi GO. Linear energy transfer dependence of Al2O3:C optically stimulated luminescence detectors exposed to therapeutic proton beams. Radiat. Meas. In Press.
2. Granville DA, Sahoo N, Sawakuchi GO. Calibration of the Al2O3:C optically stimulated luminescence (OSL) signal for linear energy transfer (LET) measurements in therapeutic proton beams. Phys Med Biol 59(15). e-Pub 7/2014. PMID: 25029434.
3. Zhu XR, Poenisch F, Lii M, Sawakuchi GO, Titt U, Bues M, Song X, Zhang X, Li Y, Ciangaru G, Li H, Taylor MB, Suzuki K, Mohan R, Gillin MT, Sahoo N. Commissioning dose computation models for spot scanning proton beams in water for a commercially available treatment planning system. Med Phys 40(4):041723, 4/2013. PMCID: PMC3631269.
4. Derveni M, Allen M, Sawakuchi GO, Yukihara EG, Richter L, Sims MR, Cullen DC. Survivability of immunoassay reagents exposed to the space radiation environment onboard the ESA BIOPAN-6 platform as a prelude to performing immunoassays on Mars. Astrobiology 13(1):92-102, 1/2013. e-Pub 1/3/2013. PMID: 23286207.
5. Omotayo AA, Cygler JE, Sawakuchi GO. The effect of different bleaching wavelengths on the sensitivity of Al2O3:C optically stimulated luminescence detectors (OSLDs) exposed to 6 MV photon beams. Med Phys 39(9):5457-68, 9/2012. PMID: 22957613.
6. Anand A, Sahoo N, Zhu XR, Sawakuchi GO, Poenisch F, Amos RA, Ciangaru G, Titt U, Suzuki K, Mohan R, Gillin MT. A procedure to determine the planar integral spot dose values of proton pencil beam spots. Med Phys 39(2):891-900, 2/2012. PMCID: PMC3277608.
7. Sawakuchi GO, Yukihara EG. Analytical modeling of relative luminescence efficiency of Al2O3:C optically stimulated luminescence detectors exposed to high-energy heavy charged particles. Phys Med Biol 57(2):437-54, 1/21/2012. e-Pub 12/15/2011. PMID: 22173080.
8. Bartz JA, Sykora GJ, Underwood TH, Nichiporov DN, Sawakuchi GO, Akselrod MS. Evaluation of aluminum oxide fluorescent and OSL detectors in proton radiotherapy beams. Radiat Meas 46:1974-1978, 2011.
9. Perles LA, Mirkovic D, Sawakuchi GO, Titt U. Monte Carlo investigation of rebinning material density distributions of lung parenchyma phantoms in proton therapy. Nucl Tech 175:22-26, 2011.
10. Titt U, Mirkovic D, Sawakuchi GO, Perles LA, Newhauser WD, Taddei PJ, Mohan R. Adjustment of the lateral and longitudinal size of scanned proton beam spots using a pre-absorber to optimize penumbrae and delivery efficiency. Phys Med Biol 55(23):7097-106, 12/7/2010. e-Pub 11/12/2010. PMCID: PMC3001334.
11. Sawakuchi GO, Sahoo N, Gasparian PB, Rodriguez MG, Archambault L, Titt U, Yukihara EG. Determination of average LET of therapeutic proton beams using Al2O3:C optically stimulated luminescence (OSL) detectors. Phys Med Biol 55(17):4963-76, 9/7/2010. e-Pub 8/6/2010. PMID: 20693613.
12. Sawakuchi GO, Mirkovic D, Perles LA, Sahoo N, Zhu XR, Ciangaru G, Suzuki K, Gillin MT, Mohan R, Titt U. An MCNPX Monte Carlo model of a discrete spot scanning proton beam therapy nozzle. Med Phys 37(9):4960-70, 9/2010. PMCID: PMC2941520.
13. Sawakuchi GO, Zhu XR, Poenisch F, Suzuki K, Ciangaru G, Titt U, Anand A, Mohan R, Gillin MT, Sahoo N. Experimental characterization of the low-dose envelope of spot scanning proton beams. Phys Med Biol 55(12):3467-78, 6/21/2010. e-Pub 5/28/2010. PMID: 20508318.
14. Sawakuchi GO, Titt U, Mirkovic D, Ciangaru G, Zhu XR, Sahoo N, Gillin MT, Mohan R. Monte Carlo investigation of the low-dose envelope from scanned proton pencil beams. Phys Med Biol 55(3):711-721, 2/7/2010. e-Pub 1/13/2010. PMID: 20071752.
15. Gillin MT, Sahoo N, Bues M, Ciangaru G, Sawakuchi G, Poenisch F, Arjomandy B, Martin C, Titt U, Suzuki K, Smith AR, Zhu XR. Commissioning of the discrete spot scanning proton beam delivery system at the University of Texas M.D. Anderson Cancer Center, Proton Therapy Center, Houston. Med Phys 37(1):154-63, 1/2010. PMID: 20175477.
16. Yukihara EG, Gasparian PBR, Sawakuchi GO, Ruan C, Ahmad S, Kalavagunta C, Clouse WJ, Sahoo N, Titt U. Medical applications of optically stimulated luminescence dosimeters (OSLDs). Radiat Meas 45:658-662, 2010.
17. Ciangaru G, Sahoo N, Zhu XR, Sawakuchi GO, Gillin MT. Computation of doses for large-angle Coulomb scattering of proton pencil beams. Phys Med Biol 54(24):7285-7300, 12/21/2009. e-Pub 11/20/2009. PMID: 19926912.
18. Reitz G, Berger T, Bilski P, Facius R, Hajek M, Petrov V, Puchalska M, Zhou D, Bossler J, Akatov Y, Shurshakov V, Olko P, Ptaszkiewicz M, Bergmann R, Fugger M, Vana N, Beaujean R, Burmeister S, Bartlett D, Hager L, Pálfalvi J, Szabó J, O'Sullivan D, Kitamura H, Uchihori Y, Yasuda N, Nagamatsu A, Tawara H, Benton E, Gaza R, McKeever S, Sawakuchi G, Yukihara E, Cucinotta F, Semones E, Zapp N, Miller J, Dettmann J. Astronaut's organ doses inferred from measurements in a human phantom outside the international space station. Radiat Res 171(2):225-35, 2/2009. PMID: 19267549.
19. Sawakuchi GO, Titt U, Mirkovic D, Mohan R. Density heterogeneities and the influence of multiple Coulomb and nuclear scatterings on the Bragg peak distal edge of proton therapy beams. Phys Med Biol 53(17):4605-19, 9/7/2008. e-Pub 8/4/2008. PMID: 18678928.
20. Vanhavere F, Genicot JL, O'Sullivan D, Sawakuchi GO, Spurny F, Yukihara EG, Zhou D. Dosimetry of biological experiments in space (DOBIES) with luminescence (OSL and TL) and track detectors. Radiat Meas 43:694-697, 2008.
21. Sawakuchi GO, Yukihara EG, McKeever SWS, Benton ER. Optically stimulated luminescence fluence response of Al2O3:C. Radiat Meas 43:450-454, 2008.
22. Sawakuchi GO, Yukihara EG, McKeever SWS, Benton. Overlap of heavy charged particle tracks and the change in shape of optically stimulated luminescence curves of Al2O3:C. Radiat Meas 43:194-198, 2008.
23. Sawakuchi GO, Yukihara EG, McKeever SWS, Gaza R, Benton ER, Uchihori Y, Yasuda N, Kitamura H. Relative optically stimulated luminescence and thermoluminescence efficiencies of Al2O3:C dosimeters to heavy charged particles with energies relevant to space and radiotherapy dosimetry. J Appl Phys 104:124903, 2008.
24. Edmund JM, Anderson CE, Greilich S, Sawakuchi GO, Yukihara EG, Jain M, Hajdas W, Mattson S. Optically stimulated luminescence from Al2O3:C irradiated with 10-60 MeV protons. Nucl Instr Meth Phys Res A 580:210-213, 2007.
25. Yukihara EG, Sawakuchi GO, Guduru S, McKeever SWS, Gaza R, Benton ER. Application of the optically stimulated luminescence technique in space dosimetry. Radiat Meas 41:1126-1135, 2006.
26. Sawakuchi GO, Okuno E. The role of aluminum and titanium in the point defects of gamma irradiated natural quartz. Phys Stat Sol (c) 2:588-591, 2005.
27. Sawakuchi GO, Okuno E. Effects of high gamma ray doses in quartz. Nucl Instrum Meth Phys Res B 218:217-221, 2004.

Grant & Contract Support

Title: Validation of Monte Carlo calculated correction factors for ionization chambers used in magnetic fields
Funding Source: Elekta
Role: Principal Investigator
Duration: 10/21/2014 - 10/20/2015
Title: The role of reactive oxygen species in gold nanoparticle radiosensitization in clinical MV beams
Funding Source: Center for Radiation Oncology Research Seed Fund, The University of Texas MD Anderson Cancer Center
Role: Principal Investigator
Duration: 10/8/2014 - 10/7/2015
Title: Synaptic mechanisms of cognitive decline after cranial radiation
Funding Source: Cancer Prevention & Research Institute of Texas (CPRIT)
Role: Collaborator
Principal Investigator: Grosshans
Duration: 9/1/2014 - 8/31/2017
Title: Real-time volumetric scintillation dosimetry for radiation therapy
Funding Source: NIH/NCI
Role: Collaborator
Principal Investigator: Beddar
Duration: 8/1/2014 - 7/31/2017

Last updated: 10/2/2014