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Gabriela Rondon, M.D.

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Stem Cell Transplantation, Division of Cancer Medicine, University of Texas, MD Anderson Cancer Center, Houston, TX

Bio Statement

Dr. Gabriela Rondón is an Assistant Professor in the Department of Stem Cell Transplantation and Cellular Therapy at the M. D. Anderson Cancer Center in Houston, Texas. She completed her Post Doctoral fellowship training here at the University of Texas M. D. Anderson, and began her tenure in 1995. She has made important clinical observations resulting in the description of a “graft versus leukemia effect in CLL” as well as defining the role of different strategies for treatment of graft failure that has led to our current “standards of practice” within the department. She also developed our current guidelines for adverse event reporting in the context of high dose therapy and stem cell transplantation. These guidelines led to a more homogeneous and relevant reporting of adverse outcomes in these settings of high dose therapy and stem cell transplantation. Dr. Rondón has been a close collaborator of Dr. Naoto Ueno in the area of high dose chemotherapy for solid tumors and with Dr Martin Korbling in his research related to the potential role of stem cell plasticity. In recent years research administration has been her primary responsibility within the department as,
The Director of Protocol Research and Data Management. She has been actively involved in implementing strategies to assure successful protocol development and execution. She has also lead one of our most important obligations related to our data management activities with the Center for International Blood and Marrow Transplant Research (CIBMTR) and is an active member of hematology and oncology professional societies including American Association for Cancer Research, American Society of Hematology, and American Society for Blood and Marrow Transplantation.


 

Office Address

The University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd
Unit Number: 423
Houston, TX 77030
Room Number: Faculty Center, FC5.3010

Education & Training

Degree-Granting Education

1985 Universidad Central de Venezuela, Caracas, Venezuela, MedicoCirujano, Medicine

Postgraduate Training

9/1992-9/1994 Post-Doctoral Fellow, Hematology, The University of Texas MD Anderson Cancer Center, Houston, TX, M. Andreeff
10/1991-9/1992 Post-Doctoral Fellow, Pheresis and Bone Marrow Transplantation, The University of Texas MD Anderson Cancer Center, Houston, TX, J Hester
8/1986-1/1987 Post -Doctoral Fellow, Pharmacology & Cell Biophysics, University of Cincinnati, Cincinnati, OH, J Hartman

Honors and Awards

1999 Excellence in Data Management, M.D. Anderson Cancer Center Office of Protocol Research Quality Assurance

Selected Publications

Peer-Reviewed Original Research Articles
1. Ramos CA, Saliba RM, de Pádua Silva L, Khorshid O, Shpall EJ, Giralt S, Patah PA, Hosing CM, Popat UR, Rondon G, Nieto Y, Champlin RE, de Lima M. Resolved Hepatitis B Virus Infection Is Not Associated with Worse Outcome after Allogeneic Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant 16(5):686-694, 5/2010. e-Pub 1/2010. PMID: 20056165.
2. Ciurea SO, Saliba R, Rondon G, Pesoa S, Cano P, Fernandez-Vina M, Qureshi S, Worth LL, McMannis J, Kebriaei P, Jones RB, Korbling M, Qazilbash M, Shpall EJ, Giralt S, de Lima M, Champlin RE, Gajewski J. Reduced-intensity conditioning using fludarabine, melphalan and thiotepa for adult patients undergoing haploidentical SCT. Bone Marrow Transplant 45(3):429-36, 3/2010. e-Pub 8/10/2009. PMID: 19668237.
3. Cheng YC, Rondón G, Sanchez LF, McMannis JD, Couriel DR, de Lima MJ, Hosing C, Khouri IF, Giralt SA, Champlin RE, Ueno NT. Interleukin-2 and granulocyte-macrophage-colony-stimulating factor immunomodulation with high-dose chemotherapy and autologous hematopoietic stem cell transplantation for patients with metastatic breast cancer. Int J Hematol 90(5):627-34, 12/2009. e-Pub 12/2009. PMID: 19998065.
4. Parmar S, Del Lima M, Zou Y, Patah PA, Liu P, Cano P, Rondon G, Pesoa S, de Padua Silva L, Qazilbash MH, Hosing C, Popat U, Kebriaei P, Shpall EJ, Giralt S, Champlin RE, Stastny P, Fernandez-Vina M. Donor-recipient mismatches in MHC class I chain-related gene A in unrelated donor transplantation lead to increased incidence of acute graft-versus-host disease. Blood 114(14):2884-7, 10/2009. e-Pub 8/2009. PMID: 19654407.
5. de Souza JA, Saliba RM, Patah P, Rondon G, Ribeiro R, de Padua Silva L, Qazilbash MH, Hosing C, Popat U, Efebera Y, Champlin RE, de Lima M. Moderate renal function impairment does not affect outcomes of reduced-intensity conditioning with fludarabine and melphalan for allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 15(9):1094-9, 9/2009. PMID: 19660722.
6. de Souza JA, Davis ML, Rondon G, Cheng YC, Jones RB, Champlin RE, Ueno NT. Prolonged disease control by nonmyeloablative allogeneic transplantation for metastatic breast cancer. Bone Marrow Transplant 44(2):81-7, 7/2009. e-Pub 5/2009. PMID: 19448681.
7. Tam CS, Bassett R, Ledesma C, Korbling M, Alousi A, Hosing C, Kebraei P, Harrell R, Rondon G, Giralt SA, Anderlini P, Popat U, Pro B, Samuels B, Hagemeister F, Medeiros LJ, Champlin RE, Khouri IF. Mature results of the M. D. Anderson Cancer Center risk-adapted transplantation strategy in mantle cell lymphoma. Blood 113(18):4144-52, 4/2009. e-Pub 1/2009. PMID: 19168784.
8. Ramos CA, Saliba RM, de Pádua L, Khorshid O, Shpall EJ, Giralt S, Patah PA, Hosing CM, Popat UR, Rondon G, Khouri IF, Nieto YL, Champlin RE, de Lima M. Impact of hepatitis C virus seropositivity on survival after allogeneic hematopoietic stem cell transplantation for hematologic malignancies. Haematologica 94(2):249-57, 2/2009. e-Pub 1/2009. PMCID: PMC2635398.
9. Rondón G, Saliba RM, Khouri I, Giralt S, Chan K, Jabbour E, McMannis J, Champlin R, Shpall E. Long-term follow-up of patients who experienced graft failure postallogeneic progenitor cell transplantation. Results of a single institution analysis. Biol Blood Marrow Transplant 14(8):859-66, 8/2008. PMID: 18640568.
10. Jabbour E, Rondon G, Anderlini P, Giralt SA, Couriel DR, Champlin RE, Khouri IF. Treatment of donor graft failure with nonmyeloablative conditioning of fludarabine, antithymocyte globulin and a second allogeneic hematopoietic transplantation. Bone Marrow Transplant 40(5):431-5, 9/2007. PMID: 17603511.
11. Wong R, Rondon G, Saliba RM, Shannon VR, Giralt SA, Champlin RE, Ueno NT. Idiopathic pneumonia syndrome after high-dose chemotherapy and autologous hematopoietic stem cell transplantation for high-risk breast cancer. Bone Marrow Transplant 31(12):1157-63, 6/2003. PMID: 12796796.
12. Montemurro F, Rondon G, Ueno NT, Munsell M, Gajewski JL, Champlin RE. Factors affecting progression-free survival in hormone-dependent metastatic breast cancer patients receiving high-dose chemotherapy and hematopoietic progenitor cell transplantation: role of maintenance endocrine therapy. Bone Marrow Transplant 29(10):861-6, 5/2002. PMID: 12058236.
13. Korbling M, Katz RL, Khanna A, Ruifrok AC, Rondon G, Albitar M, Champlin RE, Estrov Z. Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cells. N Engl J Med 346(10):738-46, 3/2002. PMID: 11882729.
14. Montemurro F, Ueno NT, Rondon G, Aglietta M, Champlin RE. High-dose chemotherapy with hematopoietic stem-cell transplantation for breast cancer: current status, future trends. Clin Breast Cancer 1(3):197-209; discussion 210, 10/2000. PMID: 11899644.
15. Hortobagyi GN, Buzdar AU, Theriault RL, Valero V, Frye D, Booser DJ, Holmes FA, Giralt S, Khouri I, Andersson B, Gajewski JL, Rondon G, Smith TL, Singletary SE, Ames FC, Sneige N, Strom EA, McNeese MD, Deisseroth AB, Champlin RE. Randomized trial of high-dose chemotherapy and blood cell autografts for high-risk primary breast carcinoma. J Natl Cancer Inst 92(3):225-33, 2/2000. PMID: 10655439.
16. Ueno NT, Rondon G, Mirza NQ, Geisler DK, Anderlini P, Giralt SA, Andersson BS, Claxton DF, Gajewski JL, Khouri IF, Korbling M, Mehra RC, Przepiorka D, Rahman Z, Samuels BI, van Besien K, Hortobagyi GN, Champlin RE. Allogeneic peripheral-blood progenitor-cell transplantation for poor-risk patients with metastatic breast cancer. J Clin Oncol 16(3):986-93, 3/1998. PMID: 9508181.
17. Rahman Z, Champlin R, Rondon G, Frye D, Valero V, Mehra R, Hortobagyi G. Phase I/II study of dose-intense doxorubicin/paclitaxel/cyclophosphamide with peripheral blood progenitor cells and cytokine support in patients with metastatic breast cancer. Semin Oncol 24:S17-77-S17-80, 10/1997. PMID: 9374100.
18. Giralt S, Estey E, Albitar M, van Besien K, Rondon G, Anderlini P, O'Brien S, Khouri I, Gajewski J, Mehra R, Claxton D, Andersson B, Beran M, Przepiorka D, Koller C, Kornblau S, Korbling M, Keating M, Kantarjian H, Champlin R. Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: harnessing graft-versus-leukemia without myeloablative therapy. Blood 89(12):4531-6, 6/1997. PMID: 9192777.
19. Rondon G, Giralt S, Pereira M, Van Besien K, Mehra R, Champlin R, Andreeff M. Analysis of chimerism following allogeneic bone marrow transplantation by fluorescent-in-situ hybridization. Leuk Lymphoma 25(5-6):463-7, 5/1997. PMID: 9250816.
20. Rondon G, Giralt S, Huh Y, Khouri I, Andersson B, Andreeff M, Champlin R. Graft-versus-leukemia effect after allogeneic bone marrow transplantation for chronic lymphocytic leukemia. Bone Marrow Transplant 18(3):669-72, 9/1996. PMID: 8879640.
21. Giralt S, Hester J, Huh Y, Hirsch-Ginsberg C, Rondon G, Seong D, Lee M, Gajewski J, Van Besien K, Khouri I, Mehra R, Przepiorka D, Korbling M, Talpaz M, Kantarjian H, Fischer H, Deisseroth A, Champlin R. CD8-depleted donor lymphocyte infusion as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation. Blood 86(11):4337-43, 12/1995. PMID: 7492795.
22. Giralt S, O’Brien S, Talpaz M, van Besien K, Chan K, Rondón G, Andersson B, Mehra R, Khouri I, Estey E, and Champlin R. Alpha Interferon and Interleukin-2 as Treatment for Leukemia Relapse After Allogeneic Bone Marrow Transplantation. Cytokines and Molecular Therapy 1/2:115-122, 1995.
23. Hester JP, Rondón G, Huh YO, Lauppe J, Champlin RE, and Deisseroth AB. Principles of Bone Marrow Processing and Progenitor Cell/Mononuclear Cell Concentrate Collection in a Continuous Flow Blood Cell Separation System. Journal of Hematotherapy 4:299-306, 1995.

Last updated: 2/18/2013