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George H. Perkins, M.D.

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

1993 University of North Carolina School of Medicine, Chapel Hill, NC, MD, Highest Honors, Medicine
1988 University of North Carolina School of Medicine, Chapel Hill, NC, Public Health Degree, with Distinction, Public Health
1987 Wake Forest University, Winston - Salem, NC, BS, Medical Sciences

Postgraduate Training

1/1999-1/2000 Fellowship in Outcomes Research, Fellowship in Breast Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Luka Milas, MD Howard Thames, PhD, Program Directo
1/1995-1/1999 Residency, Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Patricia J. Eifel, MD, Program Director
1/1994-1/1995 Internship, Mayo Clinic and Graduate School of Medicine, Jacksonville, FL, Rochester, MN., Transitional Surgery and Medicine, Mayo Clinic and Graduate School of Medicine, Rochester, MN, Gary M Lee, MD, Program Director
6/1993-6/1994 Post-Doctoral Research Fellowship Award, Lineberger Comprehensive Cancer Center Fellowship in Cancer Cell Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, Stephen Haskill, PhD and Joel Tepper, MD - Directors

Board Certifications

2022 The American Board of Radiology

Experience/Service

Academic Appointments

Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/2014-present

Honors and Awards

2008-2012 Top Doctor, Castly Connolly Medical Ltd.
2007-2012 America's Top Radiologists (Radiation Oncology), Consumer Research Council of America
2007-2012 Outstanding Health Professionals Worldwide, International Centre, Cambridge, England
2005-2013 Best Doctors In America, Best Doctors, Incorporated
2005 Luis Delclos Excellence in Teaching Award, The University of Texas M. D. Anderson Cancer Center
1999 Chairman, Quality of Education Committee (Chief Resident), The University of Texas M. D. Anderson Cancer Center
1999 National Research Service Award, The University of Texas M. D. Anderson Cancer Center
1996 Berlex Oncology Foundation Award
1995 American Medical Association/Glaxo Wellcome Residency Achievement Award, American Medical Association/Glaxo Wellcome
1993 Christopher C. Fordham III Leadership Award, Univ. of North Carolina, School of Medicine
1993 Lineberger Comprehensive Cancer Center Award, Univ. of North Carolina, School of Medicine
1992 Medical Foundation Board of Directors Merit Award, Univ. of North Carolina, School of Medicine
1991 Distinguished Medical Scholars Award, Univ. of North Carolina, School of Medicine
1990 Warwick Fellowship Award, Univ. of North Carolina School of Medicine, Great Britain National Public Health Service
1989 William B.D. MacNider Award, Univ. of North Carolina, School of Medicine
1988 Chancellor’s Scholar Award, Univ. of North Carolina, School of Medicine
1988 Delta Omega Honor Society Award, Univ. of North Carolina, School of Public Health

Selected Publications

Peer-Reviewed Original Research Articles

1. Hoffman KE, Niu J, Shen Y, Jiang J, Davis JW, Kim J, Kuban DA, Perkins GH, Shah JB, Smith GL, Volk RJ, Buchholz TA, Giordano SH, Smith BD. Physician variation in management of low-risk prostate cancer: a population-based cohort study. JAMA Intern Med. e-Pub 7/2014. PMID: 25023650.
2. Yang J, Woodward WA, Reed VK, Strom EA, Perkins GH, Tereffe W, Buchholz TA, Zhang L, Balter P, Court LE, Li XA, Dong L. Statistical modeling approach to quantitative analysis of interobserver variability in breast contouring. Int J Radiat Oncol Biol Phys 89(1):214-221, 5/1/2014. e-Pub 3/7/2014. PMCID: PMC3997068.
3. Chandwani K, Perkins GH, Nagendra HR, Raghurham NV, Spelman Am, Nagarathna R, Johnson K, Fortier A, Banu A, Wie Q, Kirschbaum C, Haddad R, Morris S, Scheetz J, Chaoul A, Cohen L. A randomized, controlled trial of yoga in women with breast cancer undergoing radiotherapy. J Clin Oncol. e-Pub 3/2014.
4. MacDermed DM, Houtman KM, Thang SH, Allen PK, Caudle AS, Gainer SM, Hunt KK, Perkins GH, Shaitelman SF, Smith BD, Strom EA, Tereffe W, Woodward WA, Buchholz TA, Hoffman KE. Therapeutic radiation dose delivered to the low axilla during whole breast radiotherapy in the prone posistion: implications for targeting the undissected axilla. Pract Radiat Oncol 4(2):116-122, Mar-Apr, 3/2014. e-Pub 7/12/2013. PMID: 24890352.
5. Takiar V, Akay CL, Stauder MC, Tereffe W, Alvarez RH, Hoffman KE, Perkins GH, Strom EA, Buchholz TA, Ueno NT, Babiera G, Woodward WA. Predictors of durable no evidence of disease status in de novo metastatic inflammatory breast cancer patients treated with neoadjuvant chemotherapy and post-mastectomy radiation. Springerplus 3:166, 2014. e-Pub 3/2014. PMCID: PMC3977020.
6. Wang X, Zhang X, Li X, Amos RA, Shaitelman SF, Hoffman K, Howell R, Salehpour M, Zhang SX, Sun TL, Smith B, Tereffe W, Perkins GH, Buchholz TA, Strom EA, Woodward WA. Accelerated partial-breast irradiation using intensity-modulated proton radiotherapy: do uncertainties outweigh potential benefits? Br J Radiol 86(1029):20130176, 9/2013. e-Pub 5/31/2013. PMCID: PMC3755395.
7. Litton JK, Warneke CL, Hahn KM, Palla SL, Kuerer HM, Perkins GH, Mittendorf EA, Barnett C, Gonzalez-Angulo AM, Hortobágyi GN, Theriault RL. Case control study of women treated with chemotherapy for breast cancer during pregnancy as compared with nonpregnant patients with breast cancer. Oncologist 18(4):369-76, 2013. e-Pub 4/2013. PMCID: PMC3639522.
8. Pinnix C, Perkins GH, Strom EA, Tereffe W, Woodward W, Oh JL, Arriaga L, Munsell MF, Kelly P, Hoffman KE, Smith BD, Buchholz TA, Yu TK. Topical hyaluronic acid vs. standard of care for the prevention of radiation dermatitis after adjuvant radiotherapy for breast cancer: single-blind randomized phase III clinical trial. Int J Radiat Oncol Biol Phys 83(4):1089-94, 7/15/2012. e-Pub 12/14/2011. PMID: 22172912.
9. Kim MM, Kudchadker RJ, Kanke JE, Zhang S, Perkins GH. Bolus electron conformal therapy for the treatment of recurrent inflammatory breast cancer: a case report. Med Dosim 37(2):208-13, 2012. e-Pub 10/5/2011. PMID: 21978532.
10. Nagar H, Mittendorf EA, Strom EA, Perkins GH, Oh JL, Tereffe W, Woodward WA, Gonzalez-Angulo AM, Hunt KK, Buchholz TA, Yu TK. Local-Regional Recurrence With and Without Radiation Therapy after Neoadjuvant Chemotherapy and Mastectomy for Clinically Staged T3n0 Breast Cancer. Int J Radiat Oncol Biol Phys 81(3):782-7, 11/1/2011. e-Pub 8/30/2011. PMID: 21885207.
11. Wang X, Amos RA, Zhang X, Taddei PJ, Woodward WA, Hoffman KE, Yu TK, Tereffe W, Oh J, Perkins GH, Salehpour M, Zhang SX, Sun TL, Gillin M, Buchholz TA, Strom EA. External-Beam Accelerated Partial Breast Irradiation Using Multiple Proton Beam Configurations. Int J Radiat Oncol Biol Phys 80(5):1464-1472, 8/1/2011. e-Pub 8/12/2010. PMCID: PMC3249354.
12. Reddy JP, Levy L, Oh JL, Strom EA, Perkins GH, Buchholz TA, Woodward WA. Long-Term Outcomes in Patients with Isolated Supraclavicular Nodal Recurrence After Mastectomy and Doxorubicin-Based Chemotherapy for Breast Cancer. Int J Radiat Oncol Biol Phys 80(5):1453-1457, 8/1/2011. e-Pub 12/16/2010. PMID: 21168284.
13. Albert JM, Buzdar AU, Guzman R, Allen PK, Strom EA, Perkins GH, Woodward WA, Hoffman KE, Tereffe W, Hunt KK, Buchholz TA, Oh JL. Prospective randomized trial of 5-fluorouracil, doxorubicin, and cyclophosphamide (FAC) versus paclitaxel and FAC (TFAC) in patients with operable breast cancer: impact of taxane chemotherapy on locoregional control. Breast Cancer Res Treat 128(2):421-7, 7/2011. e-Pub 5/8/2011. PMID: 21553292.
14. Downs-Kelly E, Bell D, Perkins GH, Sneige N, Middleton LP. Clinical Implications of Margin INvolvement by Pleomorphic Lobular Carcinoma In Situ. Arch Pathol Lab Med 135(6):737-743, 6/2011. PMID: 21631266.
15. Walker GV, Smith GL, Perkins GH, Oh JL, Woodward W, Yu TK, Hunt KK, Hoffman K, Strom EA, Buchholz TA. Population-based analysis of occult primary breast cancer with axillary lymph node metastasis. Cancer 116(17):4000-6, 9/1/2010. e-Pub 6/2010. PMID: 20564117.
16. Greenbaum MP, Strom EA, Allen PK, Perkins GH, Oh JL, Tereffe W, Yu TK, Buchholz TA, Woodward WA. Low locoregional recurrence rates in patients treated after 2000 with doxorubicin based chemotherapy modified radical mastectomy, and post-mastectomy radiation. Radiother Oncol 95(3):312-6, 6/2010. e-Pub 3/2010. PMID: 20227126.
17. Dominici LS, Kuerer HM, Babiera G, Hahn KM, Perkins G, Middleton L, Ramirez MM, Yang W, Hortobagyi GN, Theriault RL, Litton JK. Wound complications from surgery in pregnancy-associated breast cancer (PABC). Breast Dis. e-Pub 6/2010. PMID: 20519803.
18. Woodward WA, Truong PT, Yu TK, Tereffe W, Oh JL, Perkins GH, Strom EA, Meric-Bernstam F, Gonzalez-Angulo AM, Speers C, Ragaz J, Buchholz TA. Among women who experience a recurrence after postmastectomy radiation therapy irradiation is not associated with more aggressive local recurrence or reduced survival. Breast Cancer Res Treat 123(2):597-605, 3/2010.
19. Smith GL, Shih YC, Xu Y, Giordano SH, Smith BD, Perkins GH, Tereffe W, Woodward WA, Buchholz TA. Radial disparities in the use of radiotherapy after breast-conserving surgery: A national Medicare study. Cancer 116(3):734-41, 2/1/2010. e-Pub 1/2010. PMID: 20014181.
20. Zhang YJ, Oh JL, Whitman GJ, Iyengar P, Yu TK, Tereffe W, Woodward WA, Perkins G, Buchholz TA, Strom EA. Clinically apparent internal mammary nodal metastasis in patients with advance breast cancer: Incidence and local control. Int J Radiat Oncol Biol Phys. e-Pub 1/2010. PMID: 20004535.
21. Smith GL, Xu Y, Shih YC, Giordano SH, Smith BD, Hunt KK, Strom EA, Perkins GH, Hortobagyi GN, Buchholz TA. Breast conserving surgery in older patients with invasive breast cancer: current patterns of treatment across the United States. J Am Coll Surg 209(4):425-433.e2, 10/2009. e-Pub 8/20/2009. PMID: 19801315.
22. Reed VK, Woodward WA, Zhang L, Strom EA, Perkins GH, Tereffe W, Oh JL, Yu TK, Bedrosian I, Whitman GJ, Buchholz TA, Dong L. Automatic Segmentation of Whole Breast Using Atlas Approach and Deformable Image Registration. Int J Radiat Oncol Biol Phys 73(5):1493-500, 4/1/2009. e-Pub 9/17/2008. PMCID: PMC2729433.
23. Shih YC, Xu Y, Cormier JN, Giordano S, Ridner SH, Buchholz TA, Perkins GH, Elting LS. Incidence, treatment costs, and complications of lymphedema after breast cancer among women of working age: a two-year follow-up study. J Clin Oncol 27(12):2007-2014, 4/20/2009. e-Pub 3/16/2009. PMID: 19289624.
24. Ludwig MS, McNeese MD, Buchholz TA, Perkins GH, Strom EA. The lateral decubitus breast boost: description, rationale and efficacy. Int J Radiat Oncol Biol Phys 76(1). e-Pub 4/2009. PMID: 19394161.
25. Beadle BM, Woodward WA, Tucker SL, Outlaw ED, Allen PK, Oh JL, Strom EA, Perkins GH, Tereffe W, Yu TK, Meric-Bernstam F, Litton JK, Buchholz TA. Ten-Year Recurrence Rates in Young Women With Breast Cancer by Locoregional Treatment Approach. Int J Radiat Oncol Biol Phys 73(3):734-44, 3/1/2009. e-Pub 8/15/2008. PMID: 18707822.
26. Beadle BM, Woodward WA, Middleton LP, Tereffe W, Strom EA, Litton JK, Meric-Bernstam F, Theriault RL, Buchholz TA, Perkins GH. The impact of pregnancy on breast cancer outcomes in women </=35 years. Cancer 115(6):1174-1184, 3/2009. PMID: 19204903.
27. Garg AK, Frija EK, Sun TL, Strom EA, Perkins GH, Oh JL, Yu TK, Woodward WA, Tereffe WA, Salehpour M, Buchholz TA. Effects of Variable Placement of Superior Tangential/Supraclavicular Match Line on Dosimetric Coverage of Level III Axilla/Axillary Apex in Patients Treated with Breast and Supraclavicular Radiotherapy. Int J Radiat Oncol Biol Phys 73(2):370-4, 2/1/2009. PMID: 18676090.
28. Kuerer HM, Albarracin CT, Yang WT, Cardiff RD, Brewster AM, Symmans WF, Hylton NM, Middleton LP, Krishnamurthy S, Perkins GH, Babiera G, Edgerton ME, Czerniecki BJ, Arun BK, Hortobagyi GN. Ductal carcinoma in situ: State of the Science and Roadmap to Advance the Field. J Clin Oncol 27(2):279-88, 1/10/2009. e-Pub 12/8/2008. PMID: 19064970.
29. Mathew J, Perkins GH, Stephens T, Middleton LP, Yang WT. Primary breast cancer in men: clinical, imaging, and pathologic findings in 57 patients. AJR Am J Roentgenol 191(6):1631-9, 12/2008. PMID: 19020230.
30. Gadre SA, Perkins GH, Sahin AA, Sneige N, Deavers MT, Middleton LP. Neovascularization in mucinous ductal carcinoma in situ suggests an alternative pathway for invasion. Histopathology 53(5):545-53, 11/2008. PMID: 18983463.
31. Bristol IJ, Woodward WA, Strom EA, Cristofanilli M, Domain D, Singletary SE, Perkins GH, Oh JL, Yu TK, Terrefe W, Sahin AA, Hunt KK, Hortobagyi GN, Buchholz TA. Locoregional Treatment Outcomes After Multimodality Management Of Inflammatory Breast Cancer. Int J Radiat Oncol Biol Phys 72(2):474-84, 10/1/2008. e-Pub 4/24/2008. PMID: 18439768.
32. De Giorgi U, Perkins GH, Cristofanilli M. Risk of ipsilateral lung cancer after postmastectomy radiotherapy and smoking: does the possible triumph over the actual? J Clin Oncol 26(24):4044-7, 8/20/2008. PMID: 18711199.
33. Buchholz TA, Woodward WA, Duan Z, Fang S, Oh JL, Tereffe W, Strom EA, Perkins GH, Yu TK, Hunt KK, Meric-Bernstam F, Hortobagyi GN, Giordano SH. Radiation Use and Long-Term Survival in Breast Cancer Patients with T1, T2 Primary Tumors and One to Three Positive Axillary Lymph Nodes. Int J Radiat Oncol Biol Phys 71(4):1022-7, 7/15/2008. e-Pub 1/30/2008. PMID: 18234447.
34. Reed VK, Cavalcanti JL, Strom EA, Perkins GH, Oh JL, Tereffe W, Yu TK, Yeung H, Whitman GJ, Bedrosian I, Macapinlac HA, Buchholz TA, Woodward WA. Risk of subclinical micrometastatic disease in the supraclavicular nodal bed according to the anatomic distribution in patients with advanced breast cancer. Int J Radiat Oncol Biol Phys 71(2):435-40, 6/1/2008. e-Pub 12/31/2007. PMID: 18164831.
35. Smith GL, Smith BD, Giordano SH, Shih YC, Woodward WA, Strom EA, Perkins GH, Tereffe W, Yu TK, Buchholz TA. Risk of hypothyroidism in older breast cancer patients treated with radiation. Cancer 112(6):1371-9, 3/15/2008. PMID: 18213620.
36. Woodward WA, Durand JB, Tucker SL, Strom EA, Perkins GH, Oh J, Arriaga L, Domain D, Buchholz TA. Prospective analysis of carotid artery flow in breast cancer patients treated with supraclavicular irradiation 8 or more years previously: no increase in ipsilateral carotid stenosis after radiation noted. Cancer 112(2):268-73, 1/15/2008. PMID: 18000801.
37. Garg AK, Oh JL, Oswald MJ, Huang E, Strom EA, Perkins GH, Woodward WA, Yu TK, Tereffe W, Meric-Bernstam F, Hahn K, Buchholz TA. Effect of postmastectomy radiotherapy in patients <35 years old with stage II-III breast cancer treated with doxorubicin-based neoadjuvant chemotherapy and mastectomy. Int J Radiat Oncol Biol Phys 69(5):1478-83, 12/1/2007. e-Pub 9/12/2007. PMID: 17855016.
38. Oh JL, Nguyen G, Whitman GJ, Hunt KK, Yu TK, Woodward WA, Tereffe W, Strom EA, Perkins GH, Buchholz TA. Placement of radiopaque clips for tumor localization in patients undergoing neoadjuvant chemotherapy and breast conservation therapy. Cancer 110(11):2420-7, 12/1/2007. PMID: 17941034.
39. Liengsawangwong R, Yu TK, Sun TL, Erasmus JJ, Perkins GH, Tereffe W, Oh JL, Woodward WA, Strom EA, Salephour M, Buchholz TA. Treatment optimization using computed tomography-delineated targets should be used for supraclavicular irradiation for breast cancer. Int J Radiat Oncol Biol Phys 69(3):711-5, 11/1/2007. PMID: 17889264.
40. Vo T, Xing Y, Meric-Bernstam F, Mirza N, Vlastos G, Symmans WF, Perkins GH, Buchholz TA, Babiera GV, Kuerer HM, Bedrosian I, Akins JS, Hunt KK. Long-term outcomes in patients with mucinous, medullary, tubular, and invasive ductal carcinomas after lumpectomy. Am J Surg 194(4):527-31, 10/2007. PMID: 17826073.
41. Middleton LP, Perkins GH, Tucker SL, Sahin AA, Singletary SE. Expression of ERalpha and ERbeta in lobular carcinoma in situ. Histopathology 50(7):875-80, 6/2007. PMID: 17543077.
42. Borghero YO, Salehpour M, McNeese MD, Stovall M, Smith SA, Johnson J, Perkins GH, Strom EA, Oh JL, Kirsner SM, Woodward WA, Yu TK, Buchholz TA. Multileaf field-in-field forward-planned intensity-modulated dose compensation for whole-breast irradiation is associated with reduced contralateral breast dose: a phantom model comparison. Radiother Oncol 82(3):324-8, 3/2007. e-Pub 12/8/2006. PMID: 17157944.
43. Huang EH, Strom EA, Valero V, Fornage B, Perkins GH, Oh JL, Yu TK, Tereffe W, Woodward WA, Hunt KK, Meric-Bernstam F, Sahin AA, Bedrosian I, Hortobagyi GN, Buchholz TA. Locoregional treatment outcomes for breast cancer patients with ipsilateral supraclavicular metastases at diagnosis. Int J Radiat Oncol Biol Phys 67(2):490-6, 2/1/2007. PMID: 17236970.
44. Garden AS, Morrison WH, Wong PF, Tung SS, Rosenthal DI, Dong L, Mason B, Perkins GH, Ang KK. Disease-control rates following intensity-modulated radiation therapy for small primary oropharyngeal carcinoma. Int J Radiat Oncol Biol Phys 67(2):438-44, 2/2007. PMID: 17141972.
45. Woodward WA, Buchholz TA, Strom EA, Perkins GH, Middleton L, Hortobagyi GN, McNeese MD, Huang EH, Tucker SL, Hahn KM. African-American race is associated with a poorer overall survival rate for breast cancer patients treated with mastectomy and doxorubicin-based chemotherapy. Cancer 107(11):2662-68, 12/2006.
46. Oh JL, Dryden MJ, Woodward WA, Yu TK, Tereffe W, Strom EA, Perkins GH, Middleton L, Hunt KK, Giordano SH, Oswald MJ, domain D, Buchholz TA. Local-regional control of clinically diagnosed multifocal or multicentric breast cancer after neoadjuvant chemotherapy and local-regional therapy. J Clin Oncol 24(31):4971-75, 11/2006.
47. Yom SS, Morrison WH, Ang KK, Rosenthal DI, Perkins GH, Wong PF, Garden AS. Two-field versus three-field irradiation technique in the postoperative treatment of head-and-neck cancer. Int J Radiat Oncol Biol Phys 66:469-76, 10/2006. PMID: 16887292.
48. Hahn KM, Johnson PH, Gordon N, Kuerer H, Middleton L, Ramirez M, Yang W, Perkins G, Hortobagyi GN, Theriault RL. Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero. Cancer 107:1219-26, 9/2006. PMID: 16894524.
49. Huang EH, Strom EA, Perkins GH, Oh JL, chen AM, Meric-Bernstam F, Hunt KK, Sahin AA, Hortobagyi GN, Buchholz TA. Comparison of risk of local-regional recurrence after mastectomy or breast conservation therapy for patients treated with neoadjuvant chemotherapy and radiation stratified according to a prognostic index score. Int J Radiat Oncol Biol Phys 66(2):352-57, 2006.
50. Buchholz TA, Strom EA, Oswald MJ, Perkins GH, Oh JL, Domain D, Yu TK, Woodward WA, Tereffe W, Singletary SE, Thomas E, buzdar AU, Hortobagyi GN, McNeese MD. Fifteen-year results of a randomized prospective trial comparing hyperfractionated chest wall radiation versus once-daily chest wall radiation after chemotherapy and mastectomy for patients with locally advanced non-inflammatory breast cancer. Int J Radiat Oncol Biol Phys 65(4):1155-60, 2006.
51. Oh JL, Bonnen M, Outlaw ED, Schechter NR, Perkins GH, Strom EA, Babiera G, Oswald MJ, Allen PK, Thames HD, Buchholz TA. The impact of young age on locoregional recurrence after Doxorubicin-based breast conservation therapy in patients 40 years old or younger. How young is "young?". Int J Radiat Oncol biol Phys 65(5):1345-52, 2006.
52. Yom SS, Morrison WH, Ang KK, Rosenthal DI, Perkins GH, Wong PF, Garden AS. Two-field versus three-field irradiation technique in the postoperative treatment of head-and-neck cancer. Int J Radiat Oncol Biol Phys 66(2):469-76, 2006.

Last updated: 7/27/2014