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Huifang Lu, MD

Present Title & Affiliation

N/A

Education & Training

Degree-Granting Education

1995 Baylor College of Medicine, Houston, TX, PhD, Immunology and Microbiology
1988 Beijing Medical University, Beijing, China, China, MD, Medicine

Postgraduate Training

7/2002-6/2005 Clinical Fellowship, Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX
7/1999-6/2002 Clinical Residency, Internal Medicine Internship and Residency, Austin Medical Educational Programs, Austin, TX
7/1996-6/1999 Research Fellowship, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, TX
5/1995-6/1996 Research Fellowship, Leukocyte Biology, Department of Pediatrics, Baylor College of Medicine, Houston, TX

Board Certifications

2006 American Board of Allergy & Immunology
2005 American Board of Rheumatology
2002 American Board of Internal Medicine

Experience/Service

Academic Appointments

Assistant Professor, Department of General Internal Medicine, Division of Internal Medicine, Section of Rheumatology, The University of Texas MD Anderson Cancer Center, Houston, TX, 10/2005-8/2012

Administrative Appointments/Responsibilities

Director, Division of Internal Medicine, Multidisciplinary Bone Health Program Clinic, Houston, TX, 3/2013-present
Course Chair, Division of Internal Medicine, Joint Baylor/MD Anderson Rheumatology Fellowship, Multidisciplinary "Radiology/Rheumatology" 2-year curriculum, Houston, TX, 7/2010-present

Professional Memberships

American College of Rheumatology
Field Speaker's Bureau, 2011-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Lu, H, Marengo, MF, and Suarez-Almazor, ME. Rare case of septic arthritis caused by Candida Krusei: a case report and review of the literature. J Rheumatol 39(6):1308-9, 6/2012.
2. Yang T, Mendoza-Londono R, Lu H, Tao J, Li K, Keller B, Jiang MM, Shah R, Chen Y, Bertin TK, Engin F, Dabovic B, Rifkin DB, Hicks J, Jamrich M, Beaudet AL, Lee B. E-selectin lignad-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta. J Clin Invest 7(120):2474-85, 7/2010.
3. Santos FP, Konoplev SN, Lu H, Vertovsek S. Primary autoimmune myelofibrosis in a 36-year-old patient presenting with isolated extreme anemia. Leuk Res 1(34), 1/2010.
4. Cabanillas M, Lu H, Fang S, Du XL. Elderly patients with non-Hodgkin lymphoma who receive chemotherapy are at higher risk for osteoporosis and fractures. Leuk Lymphoma 48 (8):1514-21, 8/2007.
5. Berrios-Rivera JP, Lu H, Fang S, Cabanillas ME, Cabanillas F, Hu H, Du XL. Variations in chemotherapy and radiation therapy in a large nationwide and community-based cohort of elderly patients with non-Hodgkin's lymphoma. Am J Clin Oncol 30(2):163-71, 4/2007.
6. Yang Y, Xiong Z, Zhang S, Yan Y, Nguyen J, Ng B, Lu, H., Yang X. Bcl-nl inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors, 2005.
7. Lee S-H, Prince JE, Rais M, Kheradmand F, Shardonofsky F, Lu H, Smith W, Soong L. Differential requirements for CD18 in T helper effector homing. Nat Med 9(10):1281-1286, 2003.
8. Lu H, Youker K, Entman ML, Ballantyne C, Smith CW. Hydrogen peroxide induces LFA-1-dependent neutrophil adhesion to cardiac myocytes. Am J Physiology 278(3):H835-42, 2000.
9. Lu H, Ballantyne C, Smith CW. LFA-1 (CD11/CD18) triggers hydrogen peroxide production by canine neutrophils. J Leuk Biol 68:73-80, 2000.
10. Forlow SB, White EJ, Barlow SC, Feldman SH, Lu H, Bagby GJ, Beaudet AL. Severe inflammatory defect and reduced viability in CD18 and E-selectin double mutant mice. J Clin Invest 106(12):1457-1466, 2000.
11. Scharffeter K, Lu H, Norman K, van Nood N, Munoz F, Grabbe S, McArthur M, Kaplan S, Ley K, Smith CW, Montgomery CA, Rich S, Beaudet AL. Spontaneous skin ulceration and defective T cell function in CD18 null mice. J Exp Med 188:119-131, 1998.
12. Lu H, Smith CW, Perrard JL, Bullard D, Tan L, Shappell SB, Entman ML, Beaudet AL, Ballantyne CM. LFA-1 is sufficient in mediating neutrophil emigration in Mac-1 deficient mice. J Clin Invest 99:1340-1350, 1997.
13. Gopalan PK, Smith CW, Lu H, Berg EL, McIntire LB, Simon SI. Neutrophil CD18-dependent arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow can be activated through L-selectin. J Immunol 158:367-375, 1997.
14. Burns AR, SI Simon, GL Kukielka, JL Rowen, H Lu, LH Mendoza, ES Brown, ML Entman, CW Smith. Chemotactic factors stimulate CD18-dependent canine neutrophil adherence and motility on lung fibroblasts. J Immunol 156:3389-3401, 1996.
15. Manning AM, Lu H, Kukielka GL, Oliver MG, Toman CA, Krater S, Drong RF, Slightom JL, Ballantyne CM, Entman ML, Smith CW, Anderson DC. Molecular cloning and comparative sequence analysis of canine ICAM-1. Gene 24:102-120, 1996.
16. Stevens AM, Y-y Wang, KA Sieger, H Lu and L-y Yu-Lee. Biphasic transcriptional regulation of the interferon regulatory factor-1 gene by prolactin: involvement of gamma-interferon-activated sequence and Stat-related proteins. Mol. Endocrinol 9:513-525, 1995.
17. Yang T, Medoza R, Lu H, Li K, Keller B, Jiang M, Chen Y, Dobavic B, Rifkin DB, Hicks J, Beaudet AL, Lee B,. E-selectin ligard 1 negatively regulates TGFb in goldi during skeletogenesis. ASBMR Annual Meeting. Submitted.

Invited Articles

1. Lu H, Hu MI, Gagel RF. Cancer therapies and bone health. Curr Rheumatology Rep 12(3):177-85, 6/2010.
2. Lu H, DP Huston. Clinical Trial Reports on Immunodeficiency. Current Allergy Asthma Reports 3(5):375-377, 2003.

Abstracts

1. Qiuling, S. Sharon, G. Huifang, L. Charles, C. Development of anastrozole-associated joint pain and other symptoms in patients with breast cancer, 3/2012.
2. Lu H, Varma A, Popat U, Champlin RE, and Gagel RF. Risk factor for low bone mass in patients with hematological disorders/malignancies during early allogeneic stem cell transplant period. Rolantte and Berdon Lawrence Bone Disease Program Annual Scientific Retreat, 2011.
3. Shi Q, Giordano S, Lu H, Cleeland C. Longitudinal change of pain and other symptoms in breast cancer patients with anastrozole treatment. The 33rd Annual San Antonio Breast Cancer Symposium, TX, 2010.
4. Lu H, W Murphy. De Quarvein tendinits associated with the use of aromatase inhibitor. Medical Issues in Cancer Survivors, Houston, TX, 2/2009.
5. Lu H, Cabanillas M, Fang S, DU XL. Elderly patients with non-Hodgkin lymphoma who receive chemotherapy are at higher risk for osteoporosis and fractures. The 5th International Conference in Bone and Mineral Research & The 7th International Osteoporosis Symposium, Urumqi-Xinjiang, China, 5/2007.
6. Lu H. Chemotherapy is associated with increased risk of osteoporosis and fracture in elderly patients. The Bone Disease Program of Texas, 5th Annual Scientific Retreat, Houston, TX, 2007.
7. Lu H, Y Yang, DP Huston, X-F Yang. Activated T cells are novel source for secreted histamine releasing factor. Department of Medicine Research Symposium, Houston, TX, 2005.
8. Lu H. Activated T cells secrete histamine releasing factor. Asthma and Immunology 61st Annual Meeting, San Antonio, Texas, J. Allergy Clin. Immunol. 2005 115(2): S220 115(2):S220, 2005.
9. Lu H. Rheumatoid vasculitis. CIS Spring School of Autoimmune Diseases, Santa Fe, New Mexico, 2005.
10. Lu H, DP Huston, Y Liu. Schistosoma mansoni soluble egg antigen induces TSLP production by fibroblasts. GSK Fellow Symposium, San diego, CA, 2005.
11. Huston DP, Liu Y, Lu H. TGFB1-induced TSLP production. Focis centers of excellence trainee satellite symposium, 4th Annual Meeting of the Federation of clinical Immunology Societies/12th Intl Congress of Immunology, Montreal, Canada. 2004.

Book Chapters

1. Marengo MF, Suarez-Almazor M, Lu H. Neoplastic and Paraneoplastic Synovitis. In: Rheumatic Disease Clinics of North America. 37, 4. Elsevier Publisher, 551-72, 2011.
2. Waimann C, Lu H, Suarez-Almazor M. Rheumatic Manifestations of Primary and Metastatic Bone Tumors and Paraneoplastic Bone Disease. In: Rheumatic Disease Clinics of North America. 37, 4. Elsevier Publisher, 527-49, 2011.

Manuals, Teaching Aids, Other Teaching Publications

1. Lu H. Teaching Manual: How to Order Laboratory Tests for Autoimmune Disease, 2011.
2. Lu H. Teaching Manuel: Bone Health Evaluation and Treatment Algorithm, 2011.
3. Lu H and Hu M et al:. Patient education handouts on Osteoporosis, Bone Health, Calcium Supplementation, Reclast, and Prolia, 5/2010.
4. Lu H, Hu M, Gagel RF. Bone Health Video and Brochure, 2010. Awarded with Silver Medal by the National Health Information Awards, 2010.
5. Lu H. Rheumatology Consult at MD Anderson - Orientation: A How To Manuel, 2007.
6. Lu, H and Hu, M et al:. Patient education handouts on Osteoporosis, Bone Health, Calcium Supplementation, Reclast, and Prolia. Submitted.

Grant & Contract Support

Title: Long term assessment of arthralgias in breast cancer patients using Aromatase Inhibitors
Funding Source: Astrazeneca
Role: Co-Chair
Principal Investigator: Charles Cleeland
Duration: 2008 - 2011

Last updated: 7/15/2014