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Huifang Lu, MD

Present Title & Affiliation

Primary Appointment

Section of Rheumatology, Department of General Internal Medicine, Ambulatory Treatment and Emergency Care, Division of Internal Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Assistant Professor, Department of Internal Medicine, Section of Rheumatology, The University of Texas Medical School at Houston, Houston, TX

Education & Training

Degree-Granting Education

1995 Baylor College of Medicine, Houston, TX, PhD, Microbiology and Immunology
1988 Beijing Medical University, Beijing, China, China, MD, Medicine

Postgraduate Training

7/2002-6/2005 Clinical Fellowship, Immunology, Allergy and Rheumatology, Baylor College of Medicine, Houston, TX, Program Director, Dr. David P. Huston
7/1999-6/2002 Clinical Residency, Internal Medicine Internship and Residency, Austin Medical Educational Programs, Austin, TX, Program Director, Dr. Beth Miller
7/1996-6/1999 Research Fellowship, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, TX, Mentor, Arthur Beaudet, MD
5/1995-6/1996 Research Fellowship, Leukocyte Biology, Department of Pediatrics, Baylor College of Medicine, Houston, TX, Mentor, C. Wayne Smith, MD

Board Certifications

2006 American Board of Allergy & Immunology
2005 American Board of Rheumatology
2002 American Board of Internal Medicine

Experience/Service

Consultantships

Rheumatology Consultant, Harris County LBJ Hospital, Houston, TX, 12/2005-present
Rheumatology consultant, Memorial-Hermann Hospital, Houston, TX, 12/2005-2008

Institutional Committee Activities

Member at Large, Medical Records Committee, 11/2006-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Cabanillas M, Lu H, Fang S, DU XL. Elderly patients with non-Hodgkin lymphoma who receive chemotherapy are at higher risk for osteoporosis and fractures. Leuk Lymphoma 48 (8):1514-21, 8/2007.
2. Berrios-Rivera JP, Lu H, Fang S, Cabanillas ME, Cabanillas F, Hu H, Du XL. Variations in Chemotherapy and Radiation Therapy in a Large Nationwide and Community-Based Cohart of Elderly Patients with Non-Hodgins Lymphoma. Am J Clin Oncol 30(2):163-71, 4/2007.
3. Yang Y, Xiong Z, Zhang S, Yan Y, Nguyen J, Ng B, Lu, H., Yang X. Bcl-nl inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors, 2005.
4. Lu H, Huston DP. Clinical Trials Reports on Immunodeficiency, 2003.
5. Lee S-H, Prince JE, Rais M, Kheradmand F, Shardonofsky F, Lu H, Smith W, Soong L. Differential requirements for CD18 in T helper effector homing. Nat Med 9(10):1281-1286, 2003.
6. Lu H, Youker K, Entman ML, Ballantyne C, Smith CW. Hydrogen peroxide induces LFA-1-dependent neutrophil adhesion to cardiac myocytes. Am J Physiology 278(3):H835-42, 2000.
7. Lu H, Ballantyne C, Smith CW. LFA-1 (CD11/CD18) triggers hydrogen peroxide production by canine neutrophils. J Leuk Biol 68:73-80, 2000.
8. Forlow SB, White EJ, Barlow SC, Feldman SH, Lu H, Bagby GJ, Beaudet AL. Severe inflammatory defect and reduced viability in CD18 and E-selectin double mutant mice. J Clin Invest 106(12):1457-1466, 2000.
9. Scharffeter K, Lu H, Norman K, van Nood N, Munoz F, Grabbe S, McArthur M, Kaplan S, Ley K, Smith CW, Montgomery CA, Rich S, Beaudet AL. Spontaneous skin ulceration and defective T cell function in CD18 null mice. J Exp Med 188:119-131, 1998.
10. Lu H, Smith CW, Perrard JL, Bullard D, Tan L, Shappell SB, Entman ML, Beaudet AL, Ballantyne CM. LFA-1 is sufficient in mediating neutrophil emigration in Mac-1 deficient mice. J Clin Invest 99:1340-1350, 1997.
11. Gopalan PK, Smith CW, Lu H, Berg EL, McIntire LB, Simon SI. Neutrophil CD18-dependent arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow can be activated through L-selectin. J Immunol 158:367-375, 1997.
12. Burns AR, SI Simon, GL Kukielka, JL Rowen, H Lu, LH Mendoza, ES Brown, ML Entman, CW Smith. Chemotactic factors stimulate CD18-dependent canine neutrophil adherence and motility on lung fibroblasts. J Immunol 156:3389-3401, 1996.
13. Manning AM, Lu H, Kukielka GL, Oliver MG, Toman CA, Krater S, Drong RF, Slightom JL, Ballantyne CM, Entman ML, Smith CW, Anderson DC. Molecular cloning and comparative sequence analysis of canine ICAM-1. Gene 24:102-120, 1996.
14. Stevens AM, Y-y Wang, KA Sieger, H Lu and L-y Yu-Lee. Bispasic transcriptional regulation of the interferon regulatory factor-1 gene by prolaction: involvement of gamma-interferon-activated sequence and Stat-related proteins. Mol. Endocrinol 9:513-525, 1995.
15. Yang T, Medoza R, Lu H, Li K, Keller B, Jiang M, Chen Y, Dobavic B, Rifkin DB, Hicks J, Beaudet AL, Lee B,. E-selectin Ligard 1 Negatively Regulates TGFb in Goldi During Skeletogenesis. ASBMR Annual Meeting. Submitted.

Invited Articles

1. Lu H, DP Huston. Clinical Trial Reports on Immunodeficiency. Current Allergy Asthma Reports 3(5):375-377, 2003.

Abstracts

1. Lu H, W Murphy. De Quarvein Tendinits Associated with the Use of Aromatase Inhibitor. Medical Issues in Cancer Survivors, Houston, TX, 2/2009.
2. Lu H. Chemotherapy Is Associated with Increased Risk of Osteoporosis and Fracture in Elderly Patients. The Bone Disease Program of Texas, 5th Annual Scientific Retreat, Houston, TX, 2007.
3. Lu H, Y Yang, DP Huston, X-F Yang. Activated T Cells Are Novel Source for Secreted Histamine Releasing Factor. Department of Medicine Research Symposium, Houston, TX, 2005.
4. Lu H. Activated T Cells Secrete Histamine Releasing Factor. Asthma and Immunology 61st Annual Meeting, San Antonio, Texas, J. Allergy Clin. Immunol. 2005 115(2): S220 115(2):S220, 2005.
5. Lu H. Rheumatoid vasculitis. CIS Spring School of Autoimmune Diseases, Santa Fe, New Mexico, 2005.
6. Lu H, DP Huston, Y Liu. Schistosoma mansoni soluble egg antigen induces TSLP production by fibroblasts. GSK Fellow Symposium, San diego, CA, 2005.
7. Huston DP, Liu Y, Lu H. TGFB1-induced TSLP production. Focis Centers of Excellence Trainee Satellite Symposium, 4th Annual Meeting of the Federation of clinical Immunology Societies/12th Intl Congress of Immunology, Montreal, Canada., 2004.

Last updated: 8/11/2009