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Ian E. McCutcheon, M.D.

Present Title & Affiliation

Primary Appointment

Professor (with Tenure), Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Professor, Department of Neurosurgery, Division of Surgery, Baylor College of Medicine, Houston, TX

Bio Statement

Dr. Ian E.McCutcheon is a Professor in the Department of Neurosurgery at MD Anderson Cancer Center and has been a member of the department for 20 years. He is also the President of the Texas Association of Neurological Surgeons. Dr. McCutcheon’s subspecialty interests include pituitary tumors, neurofibromatosis and meningiomabiology.  At MD Anderson, he has built a pituitary tumor program that now includes 5 endocrinologists and the pituitary caseload now exceeds 100 patients annually. Dr. McCutcheon also serves as primary surgeon for the institutional program in von Hippel-Lindau disease.  His laboratory research has focused on the biology of meningiomas, and he has maintained a parallel interest in surgical strategies for treating patients with neurofibromatosis.  He has lectured nationally and internationally on these and other topics relevant to Neurosurgery, and has published over 100 papers and over 18 book chapters.  Dr. McCutcheon has also edited 3 books. 


Education & Training

Degree-Granting Education

1984 McGill University, Montreal, Quebec, Canada, MD, Medicine
1978 Yale University, New Haven, CT, BA, Chemistry

Postgraduate Training

1990-1991 Chief Resident, Neurosurgery, McGill University Hospitals and Montreal Neurological Institute, Montreal, Quebec, Canada
1989-1990 Senior Assistant Resident, Neurosurgery, Montreal Neurological Institute, Montreal, Quebec, Canada
1987-1989 Medical Staff Fellow, Neurosurgery, Surgical Neurology Branch, National Institute of Neurological, Disorders and Stroke, National Institute of Health, Bethesda, MD
1986-1987 Senior Assistant Resident, Montreal General Hospital, Montreal Children’s Hospital, Montreal, Quebec, Canada
1985-1986 Junior Assistant Resident, Neurosurgery, Montreal Neurological Institute, Montreal General Hospital, Montreal Children’s Hospital, Montreal, Quebec, Canada
1984-1985 Intern, General Surgery, Cedars-Sinai Medical Center/UCLA, Los Angeles, CA
1978-1980 Research Fellow, Cardiology, Heart Research Laboratory, University of Oregon Health Sciences Center, Portland, OR

Experience/Service

Academic Appointments

Director, Neuroendocrine Program, Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2006-present

Administrative Appointments/Responsibilities

Committee Chair, Credential Committee of the Medical Staff, The University of Texas MD Anderson Cancer Center, Houston, TX, 2009-present
Committee Chair, M. D. Anderson Physician's Network Credentials Committee, The University of Texas MD Anderson Cancer Center, Houston, TX, 2009-present
Committee Member, PRS, Clinical Cycle Revenue Committee, The University of Texas MD Anderson Cancer Center, Houston, TX, 2009-present

Honors and Awards

2006 Honored guest, Dutch Society of Neurosurgery
2003-present Best Doctors in America
1999 Feindel Lecturer, Montreal Neurological Institute, McGill University
1996-present Who’s Who in the South and Southwest
1991 Penfield-McNaughten Prize in Neurosurgery, Montreal Neurological Institute
1990-1991 President, Fellows’ Society, Montreal Neurological Institute
1989 First Prize, Poster Session, American Association of Neurological Surgeons, Annual Meeting
1983-1984 Hill Scholarship, McGill University
1983 McNaughten Prize in Writing, McGill University
1981 Summer Research Fellowship, McGill University
1980-1983 Friends of McGill Scholarship, McGill University
1977 Honors Commendations, Yale University, History Department

Selected Publications

Peer-Reviewed Original Research Articles

1. Metcalfe J, McCutcheon IE, Francisco DL, Metzenberg AB, Welch JE. Oxygen availability and growth of the chick embryo. Respir Physiol 46(2):81-8, 1981. PMID: 7335987.
2. McCutcheon IE, Metcalfe J, Metzenberg AB, Ettinger T. Organ growth in hyperoxic and hypoxic chick embryos. Respir Physiol 50(2):153-63, 1982. PMID: 7156527.
3. McCutcheon IE, Metcalfe J. Capillaries and muscle fibers in the heart of the hyperoxic chick embryo. Respir Physiol 55(1):11-22, 1984. PMID: 6231707.
4. Wagle V, McCutcheon I, Melanson D, Ethier R, Roy LE. MR in diffuse angiomatosis. AJNR Am J Neuroradiol 8:382-3, 1987. PMID: 3105298.
5. McCutcheon IE, Baranco RA, Katz DA, Saris SC. Adoptive immunotherapy of intracerebral metastases in mice. J Neurosurg 72(1):102-9, 1990. PMID: 2294169.
6. McCutcheon IE, Weintraub BD, Oldfield EH. Surgical treatment of thyrotropin-secreting pituitary adenomas. J Neurosurg 73(5):674-83, 1990. PMID: 2213157.
7. McCutcheon IE, Oldfield EH. Lymphocytic adenohypophysitis presenting as infertility. Case report. J Neurosurg 74(5):821-6, 1991. PMID: 2013781.
8. Mohanam S, Sawaya R, McCutcheon I, Ali-Osman F, Boyd D, Rao JS. Modulation of in vitro invasion of human glioblastoma cells by urokinase-type plasminogen activator receptor antibody. Cancer Res 53:4143-7, 1993. PMID: 8395977.
9. Kling MA, DeBellis MD, O'Rourke DK, Listwak SJ, Geracioti TD, Jr, McCutcheon IE, Kalogeras KT, Oldfield EH, Gold PW. Diurnal variation of cerebrospinal fluid immunoreactive corticotropin-releasing hormone levels in healthy volunteers. J Clin Endocrinol Metab 79(1):233-9, 1994. PMID: 8027234.
10. Jackson RD, Forman AD, McCutcheon IE. A referential montage selector for localization of sensorimotor cortex. Technical note. Am J EEG Technol 34:185-9, 1994.
11. Marchetti D, McCutcheon IE, Ross MI, Nicolson G. Inverse expression of neurotrophins and neurotrophin receptors at the invasion front of human melanoma brain metastases. Int J Oncol 7:87-94, 1995.
12. Robertson DP, Langford LA, McCutcheon IE. Primary xanthoma of thoracic spine presenting with myelopathy. Spine 20(17):1933-7, 1995. PMID: 8560345.
13. Yu GH, Katz RL, Raymond AK, Gagel RF, Allison A, McCutcheon IE. Oncogenous osteomalacia: Fine needle aspiration of a neoplasm with a unique endocrinologic presentation. Acta Cytol 39:831-2, 1995. PMID: 7631565.
14. McCutcheon IE, Doppman JL, Oldfield EH. Microvascular anatomy of dural arteriovenous abnormalities of the spine: a microangiographic study. J Neurosurg 84(2):215-20, 1996. PMID: 8592223.
15. Sawaya RE, Yamamoto M, Gokaslan ZL, Wang SW, Mohanam S, Fuller GN, McCutcheon IE, Stetler-Stevenson WG, Nicolson GL, Rao JS. Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo. Clin Exp Metastasis 14(1):35-42, 1996. PMID: 8521615.
16. McCutcheon IE, Blacklock JB, Weber RS, DeMonte F, Moser RP, Byers M, Goepfert H. Anterior transcranial (craniofacial) resection of tumors of the paranasal sinuses: surgical technique and results. Neurosurgery 38(3):471-9; discussion 479-80, 1996. PMID: 8837798.
17. Akeyson EW, McCutcheon IE, Pershouse MA, Steck PA, Fuller GN. Primitive neuroectodermal tumor of the median nerve. Case report with cytogenetic analysis. J Neurosurg 85(1):163-9, 1996. PMID: 8683268.
18. Hammoud MA, McCutcheon IE, Elsouki R, Schoppa D, Patt YZ. Colorectal carcinoma and brain metastasis: Distribution, treatment, and survival. Ann Surg Oncol 3(5):453-63, 1996. PMID: 8876887.
19. Akeyson EW, McCutcheon IE. Single-stage posterior vertebrectomy and replacement combined with posterior instrumentation for spinal metastasis. J Neurosurg 85(2):211-20, 1996. PMID: 8755748.
20. Chow TS, McCutcheon IE. The surgical treatment of metastatic spinal tumors within the intradural extramedullary compartment. J Neurosurg 85(2):225-30, 1996. PMID: 8755750.
21. Sivaparvathi M, McCutcheon IE, Sawaya R, Nicolson GL, Rao JS. Expression of cysteine protease inhibitors in human gliomas and meningiomas. Clin Exp Metastasis 14:344-50, 1996. PMID: 8878408.
22. Fuller GN, Kaba SE, Ginsberg LE, McCutcheon IE, Langford LA. Late sequelae of treated pleomorphic xanthoastrocytoma: Malignant brain stem astrocytoma occurring 15 years after radiation therapy. J Neurooncol 32(1):57-61, 1997. PMID: 9049863.
23. Przepiorka D, Jaeckle KA, Birdwell RR, Fuller GN, Kumar AJ, Huh YO, McCutcheon IE. Successful treatment of progressive multifocal leukoencephalopathy with low-dose interleukin-2. Bone Marrow Transplant 20:983-7, 1997. PMID: 9422479.
24. Walsh GL, Gokaslan ZL, McCutcheon IE, Mineo MT, Yasko AW, Swisher SG, Schrump DS, Nesbitt JC, Putnam JB, Jr, Roth JA. Anterior approaches to the thoracic spine in patients with cancer: indications and results. Ann Thorac Surg 64(6):1611-8, 1997. PMID: 9436544.
25. Zhu Z, McCutcheon IE, Lopes MB, Laws ER, Jr, Wagner VL, Bruner JM, Fuller GN, Langford LA, Ang LW, Friend KE. Sulfonylurea receptor mRNA expression in pituitary macroadenomas. Endocrine 8(1):7-12, 1998. PMID: 9666339.
26. Gokaslan ZL, York JE, Walsh GL, McCutcheon IE, Lang FF, Putnam JB, Jr, Wildrick DM, Swisher SG, Abi-Said D, Sawaya R. Transthoracic vertebrectomy for metastatic spinal tumors. J Neurosurg 89(4):599-609, 1998. PMID: 9761054.
27. Gagel RF, McCutcheon IE. Images in clinical medicine. Pituitary gigantism. N Engl J Med 340(7):524, 2/1999. PMID: 10021473.
28. Groves MD, McCutcheon IE, Ginsberg LE, Kyritsis AP. Radicular pain can be a symptom of elevated intracranial pressure. Neurology 52(5):1093-5, 1999. PMID: 10102441.
29. Maldonado M, Orlander P, Roshan SY, McCutcheon IE, Cleary KR, Friend KE. Sarcoidosis after surgically induced remission of Cushing's disease. Endocr Pract 5(1):43-5, Jan-Feb, 1999. PMID: 15251702.
30. Friend KE, Radinsky R, McCutcheon IE. Growth hormone receptor expression and function in meningiomas: effect of a specific receptor antagonist. J Neurosurg 91(1):93-9, 1999. PMID: 10389886.
31. Jensen R, McCutcheon IE, DeMonte F. Postoperative swelling of pericranial pedicle graft producing intracranial mass effect. Report of two cases. J Neurosurg 91(1):124-7, 1999. PMID: 10389891.
32. York JE, Walsh GL, Lang FF, Putnam JB, McCutcheon IE, Swisher SG, Komaki R, Gokaslan ZL. Combined chest wall resection with vertebrectomy and spinal reconstruction for the treatment of Pancoast tumors. J Neurosurg 91/Suppl 1(1 Suppl):74-80, 1999. PMID: 10419372.
33. Miller DJ, Steinmetz M, McCutcheon IE. Vertex epidural hematoma: surgical versus conservative management: two case reports and review of the literature. Neurosurgery 45(3):621-4; discussion 624-5, 1999. PMID: 10493382.
34. McCutcheon IE, Eng DY, Logothetis CJ. Brain metastasis from prostate carcinoma: Antemortem recognition and outcome after treatment. Cancer 86(11):2301-11, 1999. PMID: 10590371.
35. Gandhi S, Walsh GL, Komaki R, Gokaslan ZL, Nesbitt JC, Putnam JB, Jr, Roth JA, Merriman KW, McCutcheon IE, Munden RF, Swisher SG. A multidisciplinary surgical approach to superior sulcus tumors with vertebral invasion. Ann Thorac Surg 68(5):1778-84; discussion 1784-5, 1999. PMID: 10585058.
36. McCutcheon IE, Friend KE, Gerdes TM, Zhang BM, Wildrick DM, Fuller GN. Intracranial injection of human meningioma cells in athymic mice: an orthotopic model for meningioma growth. J Neurosurg 92(2):306-14, 2000. PMID: 10659019.
37. Wong ML, Kling MA, Munson PJ, Listwak S, Licinio J, Prolo P, Karp B, McCutcheon IE, Geracioti TD, Jr, DeBellis MD, Rice KC, Goldstein DS, Veldhuis JD, Chrousos GP, Oldfield EH, McCann SM, Gold PW. Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: relation to hypercortisolism and corticotropin-releasing hormone. Proc Natl Acad Sci U S A 97(1):325-30, 2000. PMCID: PMC26662.
38. Yeung SJ, McCutcheon IE, Schultz P, Gagel RF. Use of long-term intravenous phosphate infusion in the palliative treatment of tumor-induced osteomalacia. J Clin Endocrinol Metab 85(2):549-55, 2000. PMID: 10690854.
39. Jin W, McCutcheon IE, Fuller GN, Huang ES, Cote GJ. Fibroblast growth factor receptor-1 alpha-exon exclusion and polypyrimidine tract-binding protein in glioblastoma multiforme tumors. Cancer Res 60(5):1221-4, 2000. PMID: 10728679.
40. McCutcheon IE, Pieper DR, Fuller GN, Benjamin RS, Friend KE, Gagel RF. Pituitary carcinoma containing gonadotropins: treatment by radical excision and cytotoxic chemotherapy: Case report. Neurosurgery 46(5):1233-9; discussion 1239-40, 2000. PMID: 10807257.
41. Schultz PN, Ginsberg L, McCutcheon IE, Samaan N, Leavens M, Gagel RF. Quinagolide in the management of prolactinoma. Pituitary 3(4):239-49, 2000. PMID: 11788012.
42. Fourney DR, Abi-Said D, Lang FF, McCutcheon IE, Gokaslan ZL. Use of pedicle screw fixation in the management of malignant spinal disease: experience in 100 consecutive procedures. J Neurosurg 94/Suppl 1(1 Suppl):25-37, 2001. PMID: 11147865.
43. Ellerhorst J, Strom E, Nardone E, McCutcheon IE. Whole brain irradiation for patients with metastatic melanoma: A review of 87 cases. Int J Radiat Oncol Biol Phys 49:93-7, 2001. PMID: 11163501.
44. McCutcheon IE, Flyvbjerg A, Hill H, Li J, Bennett WF, Scarlett JA, Friend KE. Antitumor activity of the growth hormone receptor antagonist pegvisomant against human meningiomas in nude mice. J Neurosurg 94(3):487-92, 2001. PMID: 11235955.
45. Michael CB, Gokaslan ZL, DeMonte F, McCutcheon IE, Sawaya R, Lang FF. Surgical resection of calvarial metastases overlying dural sinuses. Neurosurgery 48(4):745-54; discussion 754-5, 2001. PMID: 11322434.
46. Fourney DR, Abi-Said D, Rhines LD, Walsh GL, Lang FF, McCutcheon IE, Gokaslan ZL. Simultaneous anterior-posterior approach to the thoracic and lumbar spine for the radical resection of tumors followed by reconstruction and stabilization. J Neurosurg 94/Suppl 2(2 Suppl):232-44, 2001. PMID: 11302626.
47. McCutcheon IE, Kitagawa RH, Sherman SI, Bruner JM. Adenocarcinoma of the salivary gland metastatic to the pituitary gland: Case report. Neurosurgery 48(5):1161-5; discussion 1165-6, 2001. PMID: 11334286.
48. Friend KE, Khandwala HM, Flyvbjerg A, Hill H, Li J, McCutcheon IE. Growth hormone and insulin-like growth factor-I: effects on the growth of glioma cell lines. Growth Horm IGF Res 11(2):84-91, 2001. PMID: 11472074.
49. Lacroix M, Abi-Said D, Fourney DR, Gokaslan ZL, Shi W, DeMonte F, Lang FF, McCutcheon IE, Hassenbusch SJ, Holland E, Hess K, Michael C, Miller D, Sawaya R. A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival. J Neurosurg 95(2):190-8, 2001. PMID: 11780887.
50. Hanbali F, Fourney DR, Marmor E, Suki D, Rhines LD, Weinberg JS, McCutcheon IE, Suk I, Gokaslan ZL. Spinal cord ependymoma: Radical surgical resection and outcome. Neurosurgery 51(5):1162-72; discussion 1172-4, 2002. PMID: 12383361.
51. Brown HM, McCutcheon IE, Leeds NE, Schomer DS, Luna MA, Fuller GN. Melanoma metastatic to central neurocytoma: A novel case of tumor-to-tumor metastasis. J Neurooncol 61(3):209-14, 2003. PMID: 12675313.
52. Hentschel SJ, McCutcheon IE, Moore W, Durity FA. p53 and MIB-1 labeling index as predictors of the clinical behavior of nonfunctional pituitary adenomas. Can J Neurol Sci 30(3):215-9, 8/2003. PMID: 12945944.
53. Lee HK, Chang EL, Fuller GN, Aldape KD, Atkinson GJ, Levy LB, McCutcheon IE, Maor MH. The prognostic value of neurologic function in astrocytic spinal cord glioma. Neuro Oncol 5(3):208-13, 2003. PMCID: PMC1920688.
54. Prabhu SS, Aldape KD, Gagel RF, Benjamin RS, Trent JC, McCutcheon IE. Sarcomatous change after sellar irradiation in a growth hormone-secreting pituitary adenoma. Can J Neurol Sci 30(4):378-83, 2003. PMID: 14672272.
55. McCutcheon IE, Hentschel SJ, Fuller GN, Jin W, Cote GJ. Expression of the splicing regulator polypyrimidine tract-binding protein in normal and neoplastic brain. Neuro Oncol 6/1(1):9-14, 2004. PMCID: PMC1871971.
56. McCutcheon IE, Kitagawa RS, Demasi PF, Law BK, Friend KE. Frameless stereotactic navigation in transsphenoidal surgery: comparison with fluoroscopy. Stereotact Funct Neurosurg 82(1):43-8, 2004. PMID: 15007219.
57. Soyuer S, Chang EL, Selek U, McCutcheon IE, Maor MH. Intracranial meningeal hemangiopericytoma: the role of radiotherapy: report of 29 cases and review of the literature. Cancer 100(7):1491-7, 2004. PMID: 15042684.
58. Hentschel SJ, Rhines LD, Wong FC, Gokaslan ZL, McCutcheon IE. Subarachnoid-pleural fistula after resection of thoracic tumors. J Neurosurg 100(4 Suppl Spine):332-6, 2004. PMID: 15070140.
59. Ribalta T, McCutcheon IE, Neto AG, Gupta D, Kumar AJ, Biddle DA, Langford LA, Bruner JM, Leeds NE, Fuller GN. Textiloma (gossypiboma) mimicking recurrent intracranial tumor. Arch Pathol Lab Med 128(7):749-58, 2004. PMID: 15214828.
60. Vora YA, Raad,, II, McCutcheon IE. Intramedullary abscess from group F Streptococcus. Surg Infect (Larchmt) 5(2):200-4, 2004. PMID: 15353118.
61. Ezzat S, Asa SL, Couldwell WT, Barr CE, Dodge WE, Vance ML, McCutcheon IE. The prevalence of pituitary adenomas: A systematic review. Cancer 101(3):613-9, 2004. PMID: 15274075.
62. Hentschel SJ, McCutcheon IE, Ginsberg L, Weinberg JS. Exophytic ependymomas of the spinal cord. Acta Neurochir (Wien) 146(9):1047-50, 2004. e-Pub 5/10/2004. PMID: 15340819.
63. Ribalta T, McCutcheon IE, Aldape KD, Bruner JM, Fuller GN. The mitosis-specific antibody anti-phosphohistone-H3 (PHH3) facilitates rapid reliable grading of meningiomas according to WHO 2000 criteria. Am J Surg Pathol 28(11):1532-6, 2004. PMID: 15489659.
64. Neto AG, McCutcheon IE, Vang R, Spencer ML, Zhang W, Fuller GN. Elevated expression of p21 (WAF1/Cip1) in hormonally active pituitary adenomas. Ann Diagn Pathol 9(1):6-10, 2005. PMID: 15692944.
65. Puduvalli VK, Li JT, Chen L, McCutcheon IE. Induction of apoptosis in primary meningioma cultures by fenretinide. Cancer Res 65(4):1547-53, 2005. PMID: 15735044.
66. Holman PJ, Suki D, McCutcheon IE, Wolinsky JP, Rhines LD, Gokaslan ZL. Surgical management of metastatic disease of the lumbar spine: experience with 139 patients. J Neurosurg Spine 2:550-63, 2005. PMID: 15945429.
67. Mahajan A, McCutcheon IE, Suki D, Chang EL, Hassenbusch SJ, Weinberg JS, Shiu A, Maor MH, Woo SY. Case-control study of stereotactic radiosurgery for recurrent glioblastoma multiforme. J Neurosurg 103(2):210-7, 2005. PMID: 16175848.
68. Hlatky R, Jackson EF, Weinberg JS, McCutcheon IE. Intraoperative neuronavigation using diffusion tensor MR tractography for the resection of a deep tumor adjacent to the corticospinal tract. Stereotact Funct Neurosurg 83(5-6):228-32, 2005. e-Pub 3/8/2006. PMID: 16534255.
69. Kondraganti S, Gondi CS, McCutcheon I, Dinh DH, Gujrati M, Rao JS, Olivero WC. RNAi-mediated downregulation of urokinase plasminogen activator and its receptor in human meningioma cells inhibits tumor invasion and growth. Int J Oncol 28(6):1353-60, 6/2006. PMCID: PMC1459538.
70. Kondraganti S, Gondi CS, Gujrati M, McCutcheon I, Dinh DH, Rao JS, Olivero WC. Restoration of tissue factor pathway inhibitor inhibits invasion and tumor growth in vitro and in vivo in a malignant meningioma cell line. Int J Oncol 29(1):25-32, 7/2006. PMCID: PMC1479607.
71. Cheung HC, Corley LJ, Fuller GN, McCutcheon IE, Cote GJ. Polypyrimidine tract binding protein and Notch1 are independently re-expressed in glioma. Mod Pathol 19(8):1034-41, 2006. e-Pub 5/26/2006. PMID: 16729017.
72. McPherson CM, Suki D, McCutcheon IE, Gokaslan ZL, Rhines LD, Mendel E. Metastatic disease from spinal chordoma: a 10-year experience. J Neurosurg Spine 5(4):277-80, 10/2006. PMID: 17048762.
73. Akyurek S, Chang EL, Yu TK, Little D, Allen PK, McCutcheon I, Mahajan A, Maor MH, Woo SY. Spinal myxopapillary ependymoma outcomes in patients treated with surgery and radiotherapy at M.D. Anderson Cancer Center. J Neurooncol 80:177-83, 2006. PMID: 16648988.
74. Shaw SA, Camacho LH, McCutcheon IE, Waguespack SG. Transient hypophysitis after cytotoxic T lymphocyte-associated antigen 4 (CTLA4) blockade. J Clin Endocrinol Metab 92(4):1201-2, 4/2007. PMID: 17409339.
75. Shehadi JA, Sciubba DM, Suk I, Suki D, Maldaun MV, McCutcheon IE, Nader R, Theriault R, Rhines LD, Gokaslan ZL. Surgical treatment strategies and outcome in patients with breast cancer metastatic to the spine: a review of 87 patients. Eur Spine J 16(8):1179-92, 8/2007. e-Pub 4/4/2007. PMCID: PMC2200772.
76. McCutcheon IE, Waguespack SG, Fuller GN, Couldwell WT. Metastatic melanoma to the pituitary gland. Can J Neurol Sci 34(3):322-7, 8/2007. PMID: 17803030.
77. Sciubba DM, Gokaslan ZL, Suk I, Suki D, Maldaun MV, McCutcheon IE, Nader R, Theriault R, Rhines LD, Shehadi JA. Positive and negative prognostic variables for patients undergoing spine surgery for metastatic breast disease. Eur Spine J 16(10):1659-1667, 2007. e-Pub 5/8/2007. PMCID: PMC2078314.
78. Vecil GG, Papadopoulos NV, Vassilopoulou-Sellin R, McCutcheon IE. Interferon-induced hypothyroidism causing reversible pituitary enlargement. Endocr Pract 14(2):219-23, 3/2008. PMID: 18308662.
79. Feiz-Erfan I, Rao G, White WL, McCutcheon IE. Efficacy of Trans-septal Trans-sphenoidal Surgery in Correcting Visual Symptoms Caused by Hematogenous Metastases to the Sella and Pituitary Gland. Skull Base 18(2):77-84, 3/2008. PMCID: PMC2435478.
80. Rao G, Suki D, Chakrabarti I, Feiz-Erfan I, Mody MG, McCutcheon IE, Gokaslan Z, Patel S, Rhines LD. Surgical management of primary and metastatic sarcoma of the mobile spine. J Neurosurg Spine 9(2):120-8, 2008. PMID: 18764743.
81. Vecil GG, McCutcheon IE, Mendel E. Extended lateral parascapular approach for resection of a giant multi-compartment thoracic schwannoma. Acta Neurochir (Wien) 150(12). e-Pub 11/18/2008. PMID: 19015809.
82. Kim SS, McCutcheon IE, Sawaya R, Weinberg JS, Lang FF, Heimberger A, Rhines LD, Ferson DZ, Suki D, Prabhu SS. Awake craniotomy for brain tumors near eloquent cortex: correlation of intraoperative cortical mapping with neurological outcomes in 309 consecutive patients. Neurosurgery 64(5):836-45; discussion 345-6, 2009. PMID: 19404147.
83. Zou CY, Smith KD, Zhu QS, Liu J, McCutcheon IE, Slopis JM, Meric-Bernstam F, Peng Z, Bornmann WG, Mills GB, Lazar AJ, Pollock RE, Lev D. Dual targeting of AKT and mammalian target of rapamycin: A potential therapeutic approach for malignant peripheral nerve sheath tumor. Mol Cancer Ther 8(5):1157-1168, 2009. e-Pub 5/5/2009. PMID: 19417153.
84. Zou C, Smith KD, Liu J, Lahat G, Myers S, Wang WL, Zhang W, McCutcheon IE, Slopis JM, Lazar AJ, Pollock RE, Lev D. Clinical, pathological, and molecular variables predictive of malignant peripheral nerve sheath tumor outcome. Ann Surg 249(6):1014-22, 6/2009. PMID: 19474676.
85. Rao G, Giordano SH, Lui JJ, McCutcheon IE. The association of breast cancer and meningioma in men and women. Neurosurgery 65(3):483-9; discussion 489, 9/2009. PMID: 19687693.
86. Amhaz HH, Chamoun RB, Waguespack SG, Shah K, McCutcheon IE. Spontaneous involution of Rathke cleft cysts: is it rare or just underreported? J Neurosurg 112(6):1327-32, 6/2010. PMID: 19929199.
87. Hassaneen W, Suki D, Salaskar AL, Levine NB, DeMonte F, Lang FF, McCutcheon IE, Dorai Z, Feiz-Erfan I, Wildrick DM, Sawaya R. Immediate morbidity and mortality associated with transcallosal resection of tumors of the third ventricle. J Clin Neurosci 17(7):830-6, 7/2010. e-Pub 5/15/2010. PMID: 20478709.
88. Friedman TC, Ghods DE, Shahinian HK, Zachery L, Shayesteh N, Seasholtz S, Zuckerbraun E, Lee ML, McCutcheon IE. High prevalence of normal tests assessing hypercortisolism in subjects with mild and episodic Cushing's syndrome suggests that the paradigm for diagnosis and exclusion of Cushing's syndrome requires multiple testing. Horm Metab Res 42(12):874-81, 11/2010. e-Pub 8/27/2010. PMCID: PMC2978784.
89. Viswanathan A, Burton AW, Rekito A, McCutcheon IE. Commissural myelotomy in the treatment of intractable visceral pain: technique and outcomes. Stereotact Funct Neurosurg 88(6):374-82, 2010. e-Pub 10/2010. PMID: 20948242.
90. Gasco J, Barber SM, Rangel-Castilla L, McCutcheon IE, Black PM. Neurosurgery certification in member societies of the World Federation of Neurosurgical Societies (WFNS). The Americas. World Neurosurg 74(1):16-27, 7/2010. PMID: 21299979.
91. Gasco J, Barber SM, McCutcheon IE, Black PM. Neurosurgery certification in member societies of the WFNS: Europe. World Neurosurg 74(4-5):375-86, Oct-Nov, 10/2010. e-Pub 1/12/2011. PMID: 21492573.
92. Hassaneen W, Levine NB, Suki D, Salaskar AL, de Moura Lima A, McCutcheon IE, Prabhu SS, Lang FF, DeMonte F, Rao G, Weinberg JS, Wildrick DM, Aldape KD, Sawaya R. Multiple craniotomies in the management of multifocal and multicentric glioblastoma. J Neurosurg 114(3):576-84, 3/2011. e-Pub 8/6/2010. PMID: 20690813.
93. Lopez G, Torres K, Liu J, Hernandez B, Young E, Belousov R, Bolshakov S, Lazar AJ, Slopis JM, McCutcheon IE, McConkey D, Lev D. Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors. Cancer Res 71(1):185-96, 1/1/2011. e-Pub 11/16/2010. PMCID: PMC3064267.
94. Floyd JR, Keeler ER, Euscher ED, McCutcheon IE. Cyclic sciatica from extrapelvic endometriosis affecting the sciatic nerve. J Neurosurg Spine 14(2):281-9, 2/2011. e-Pub 12/24/2010. PMID: 21184633.
95. Khan MI, Habra MA, McCutcheon IE, Nogueras-González GM, Devin JK, Busaidy NL, Levine NB, Lindstrom W, Kagan D, Jimenez C, Waguespack SG. Random postoperative day 3 cortisol as a predictor of hypothalamic-pituitary-adrenal axis integrity after transsphenoidal surgery. Endocr Pract 17(5):1-25, 9/1/2011. e-Pub 3/31/2011. PMID: 21454228.
96. Gasco J, Braun JD, McCutcheon IE, Black PM. Neurosurgery certification in member societies of the WFNS: Asia. World Neurosurg 75(3-4):325-34, Mar-Apr, 3/2011. PMID: 21600456.
97. Kim KD, Wright NM, Cosgrove R, Van Loveren HR, Vale FL, Gerszten PC, Welch WC, Deutsch H, Munoz L, Karahalios DG, Tew JM Jr, Ondra SL, Shaffrey ME, Kaiser MG, Delashaw JB, Brown FD, Fessler RG, Mayberg MR, Chen TC, Wang MY, Long DM, Shah MV, Groff M, McCutcheon IE, Sharan AD, Hopkins LN, Chestnut R, Graham RS, Gross RE, Jallo J. Polyethylene Glycol (PEG) Hydrogel Spinal Sealant (DuraSeal Spinal Sealant) as an Adjunct to Sutured Dural Repair in the Spine: Results of a Prospective, Multicenter, Randomized Controlled Study. Spine (Phila Pa 1976) 36:1906-1912, 2011. e-Pub 2/2011. PMID: 21289564.
98. Gasco J, Barber SM, McCutcheon IE, Black PM. Neurosurgery certification in member societies of the WFNS: Africa and the Middle East. World Neurosurg 76(1-2):18-27; discussion 54-6, Jul-Aug, 7/2011. PMID: 21839933.
99. Gasco J, Barber SM, McCutcheon IE, Black PM. Neurosurgery certification in member societies of the WFNS: global overview. World Neurosurg 76(3-4):231-8, Sep-Oct, 9/2011. PMID: 21986411.
100. Li JT, Bian K, Zhang AL, Kim DH, Ashley WW, Nath R, McCutcheon I, Fang B, Murad F. Targeting different types of human meningioma and glioma cells using a novel adenoviral vector expressing GFP-TRAIL fusion protein from hTERT promoter. Cancer Cell Int 11(1). e-Pub 10/28/2011. PMID: 22035360.
101. Angelo LS, Wu JY, Meng F, Sun M, Kopetz S, McCutcheon IE, Slopis JM, Kurzrock R. Combining curcumin (diferuloylmethane) and heat shock protein inhibition for neurofibromatosis 2 treatment: analysis of response and resistance pathways. Mol Cancer Ther 10(11):2094-103, 11/2011. e-Pub 9/8/2011. PMID: 21903608.
102. Zhu H, Li JT, Zheng F, Martin E, Kots AY, Krumenacker JS, Choi BK, McCutcheon IE, Weisbrodt N, Bögler O, Murad F, Bian K. Restoring soluble guanylyl cyclase expression and function blocks the aggressive course of glioma. Mol Pharmacol 80(6):1076-84, 12/2011. e-Pub 9/9/2011. PMCID: PMC3228529.
103. Jonasch E, McCutcheon IE, Waguespack SG, Wen S, Davis DW, Smith LA, Tannir NM, Gombos DS, Fuller GN, Matin SF. Pilot trial of sunitinib therapy in patients with von Hippel-Lindau disease. Ann Oncol 22(12):2661-6, 12/2011. PMID: 22105611.
104. Subbiah V, Slopis J, Hong DS, Ketonen LM, Hamilton J, McCutcheon IE, Kurzrock R. Treatment of Patients With Advanced Neurofibromatosis Type 2 With Novel Molecularly Targeted Therapies: From Bench to Bedside. J Clin Oncol 30(5):e64-8, 2/10/2012. e-Pub 12/27/2011. PMCID: PMC3295556.
105. Aizenberg MR, Fox BD, Suki D, McCutcheon IE, Rao G, Rhines LD. Surgical management of unknown primary tumors metastatic to the spine. J Neurosurg Spine 16(1):86-92, 1/2012. e-Pub 10/7/2011. PMID: 21981272.
106. Kim BY, Jonasch E, McCutcheon IE. Pazopanib therapy for cerebellar hemangioblastomas in von Hippel-Lindau disease: case report. Target Oncol 7(2):145-9, 6/2012. e-Pub 2/29/2012. PMID: 22374327.
107. Hightower E, Cabanillas ME, Fuller GN, McCutcheon IE, Hess KR, Shah K, Waguespack SG, Corley LJ, Devin JK. Phospho-histone H3 (pHH3) immuno-reactivity as a prognostic marker in non-functioning pituitary adenomas. Pituitary 15(4):556-61, 12/2012. e-Pub 11/27/2011. PMID: 22120760.
108. Angelo LS, Maxwell DS, Wu JY, Sun D, Hawke DH, McCutcheon IE, Slopis JM, Peng Z, Bornmann WG, Kurzrock R. Binding partners for curcumin in human schwannoma cells: biologic implications. Bioorg Med Chem 21(4):932-939, 2/15/2013. e-Pub 12/13/2012. PMID: 23294827.
109. Trinh VT, Fahim DK, Shah K, Tummala S, McCutcheon IE, Sawaya R, Suki D, Prabhu SS. Subcortical Injury is an Independent Predictor of Worsening Neurological Deficits Following Awake Craniotomy Procedures. Neurosurgery 72(2):160-9, 2/2013. e-Pub 11/9/2012. PMID: 23147778.
110. Ghia AJ, Allen PK, Mahajan A, Penas-Prado M, McCutcheon IE, Brown PD. Intracranial Hemangiopericytoma and the Role of Radiation Therapy: A Population Based Analysis. Neurosurgery 72(2):203-9, 2/2013. e-Pub 11/12/2012. PMID: 23149953.
111. Wu AS, Trinh VT, Suki D, Graham S, Forman A, Weinberg JS, McCutcheon IE, Prabhu SS, Heimberger AB, Sawaya R, Wang X, Qiao W, Hess KR, Lang FF. A prospective randomized trial of peri-operative seizure prophylaxis in patients with intraparenchymal brain tumors. J Neurosurg 118(4):873-83, 4/2013. e-Pub 2/8/2013. PMID: 23394340.
112. Fakhreddine MH, Mahajan A, Penas-Prado M, Weinberg J, McCutcheon IE, Puduvalli V, Brown PD. Treatment, prognostic factors, and outcomes in spinal cord astrocytomas. Neuro Oncol 15(4):406-12, 4/2013. e-Pub 1/14/2013. PMCID: PMC3607259.
113. Ghia AJ, Chang EL, Allen PK, Mahajan A, Penas-Prado M, McCutcheon IE, Brown PD. Intracranial Hemangiopericytoma: Patterns of Failure and the Role of Radiation Therapy. Neurosurgery 73(4):624-30; discussion 630-1, 10/2013. e-Pub 7/8/2013. PMID: 23839520.
114. Prashant Prasad G, Lang FF, Bruner JM, Ater JL, McCutcheon IE. Transsphenoidal removal of intrasellar pilocytic astrocytoma. J Clin Neurosci. e-Pub 10/2013. PMID: 24308951.
115. Verma J, McCutcheon IE, Waguespack SG, Mahajan A. Feasibility and outcome of re-irradiation in the treatment of multiply recurrent pituitary adenomas. Pituitary. e-Pub 11/2013. PMID: 24272035.
116. Tatsui CE, Suki D, Rao G, Kim SS, Salaskar A, Hatiboglu MA, Gokaslan ZL, McCutcheon IE, Rhines LD. Factors affecting survival in 267 consecutive patients undergoing surgery for spinal metastasis from renal cell carcinoma. J Neurosurg Spine 20(1):108-16, 1/2014. e-Pub 11/8/2013. PMID: 24206037.
117. Beiko J, Suki D, Hess KR, Fox BD, Cheung V, Cabral M, Shonka N, Gilbert MR, Sawaya R, Prabhu SS, Weinberg J, Lang FF, Aldape KD, Sulman EP, Rao G, McCutcheon IE, Cahill DP. IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resection. Neuro Oncol 16(1):81-91, 1/2014. e-Pub 12/2013. PMCID: PMC3870823.

Invited Articles

1. Leavens ME, McCutcheon IE, Samaan NA. Management of pituitary adenomas. Oncology (Williston Park) 6:69-79; discussion 79-80, 1992. PMID: 1319190.
2. McCutcheon IE, Leavens ME. Diagnosis and treatment of pituitary adenomas. Cancer Bulletin 45:326-32, 1993.
3. McCutcheon IE. Multiple endocrine neoplasia. Management of individual tumor syndromes. Pituitary neoplasia. Endocrinol Metab Clin North Am 23(1):37-51, 1994. PMID: 7913028.
4. Akeyson EW, McCutcheon IE. Management of benign and aggressive intracranial meningiomas. Oncology (Williston Park) 10(5):747-56; discussion 756-9, 1996. PMID: 8738830.
5. McCutcheon IE. The biology of meningiomas. J Neurooncol 29(3):207-16, 1996. PMID: 8858526.
6. Khandwala HM, McCutcheon IE, Flyvbjerg A, Friend KE. The effects of insulin-like growth factors on tumorigenesis and neoplastic growth. Endocr Rev 21(3):215-44, 2000. PMID: 10857553.
7. Miller DJ, McCutcheon IE. Hemangioblastomas and other uncommon intramedullary tumors. J Neurooncol 47(3):253-70, 2000. PMID: 11016742.
8. Vecil GG, McCutcheon IE. Convexity meningiomas. Seminars in Neurosurgery 14:219-35, 2003.
9. Hentschel SJ, McCutcheon IE. Chemotherapy and biological therapy for meningiomas. Seminars in Neurosurgery 14:287-94, 2003.
10. Hentschel SJ, McCutcheon IE. Stereotactic radiosurgery for Cushing disease. Neurosurg Focus 16/4(4):E5, 2004. PMID: 15191334.
11. McCutcheon IE. The problem of the aggressive pituitary tumor. Touch Briefings: US Endocrine Disease 2:105-7, 2006.
12. McCutcheon IE. Pituitary adenomas: Surgery and radiotherapy in the age of molecular diagnostics and pathology. Curr Probl Cancer 37(1):6-37, Jan-Feb, 1/2013. PMID: 23391140.
13. McCutcheon IE. Stereotactic radiosurgery for malignant extracerebral intracranial tumors: patient selection, efficacy, and technical nuances. Acta Neurochir Suppl 116:71-83, 2013. PMID: 23417462.

Book Chapters

1. McCutcheon IE, Oldfield EH. Cortisol: regulation, disorders, and clinical evaluation. In: Neuroendocrinology, Concepts in Neurosurgery. 5. Ed(s) Selman W, Barrow DL. Williams & Wilkins: Baltimore, 117-73, 1992.
2. Hardy J, McCutcheon IE. Pituitary microadenomas. In: Brain Surgery, Complication Avoidance and Management. Ed(s) Apuzzo MLJ. Churchill Livingstone: New York, 276-95, 1992.
3. McCutcheon IE. Pituitary tumors. In: Cancer in the Nervous System. Churchill Livingstone: New York, 219-41, 1995.
4. McCutcheon IE, Oldfield EH. Laboratory investigation and perioperative endocrine management of sellar and parasellar tumors. In: The Practice of Neurosurgery. Ed(s) Tindall GT, Cooper PR, Barrow DL. Williams & Wilkins: Baltimore, 1091-119, 1996.
5. Friend KE, McCutcheon IE. Estrogen receptor expression in the pituitary gland. In: Sex-Steroid Interactions with Growth Hormone. Ed(s) Veldhuis JD, Giustina A. Springer-Verlag: New York, 301-7, 1999.
6. Lal S, McCutcheon IE. Infection after craniotomy. In: Infections in Neurosurgery. Ed(s) Hall WA, McCutcheon IE. American Association of Neurological Surgeons: Park Ridge, 125-40, 1999.
7. McCutcheon IE, Oldfield EH. Management of thyroid-stimulating hormone-secreting adenomas. In: Pituitary Disorders: Comprehensive Management. Ed(s) Krisht A, Tindall GT. Williams & Wilkins: Baltimore, 267-80, 1999.
8. McCutcheon IE. Primary central nervous system tumors: pituitary region. In: Cancer in the Nervous System, 2. Ed(s) Levin VA. Oxford University Press: Oxford, 208-36, 2002.
9. Conrad CA, Pro B, Prabhu SS, McCutcheon IE, DeMonte F. Primary brain tumors. In: Atlas of Cancer. Ed(s) Markman M. Lippincott Williams & Wilkins: Philadelphia, 561-93, 2003.
10. Balasingham V, McCutcheon IE. Metastatic colorectal carcinoma. In: Intracranial Metastases: Current Management Strategies. Ed(s) Sawaya R. Blackwell/Futura: New York, 279-91, 2004.
11. McCutcheon IE. Metastatic brain tumors. In: Principles of Neurosurgery, 2. Ed(s) Rengachary SR, Ellenbogen R. Mosby: Edinburgh, 479-86, 2005.
12. Hentschel SJ, McCutcheon IE. Extramedullary intradural spinal tumors. In: Spinal Cord and Spinal Column Tumors: Principles and Practice. Ed(s) Dickman CA, Fehlings MG, Gokaslan ZL. Thieme: New York, 335-48, 2006.
13. McCutcheon IE. Pituitary tumors in oncology. In: Tumors of the Brain and Spine. Ed(s) DeMonte F, Mahajan A, Gilbert M, McCutcheon IE. Springer: New Yrok, 191-223, 2007.
14. Janjan N, Mahagan A, Chang EL, McCutcheon IE, Lin E, Das P, Krishnan S, Chow E. Prognosis in spinal cord compression. In: Prognosis in Advanced Cancer. Oxford University Press: London, 2008.
15. McCutcheon IE. Transsphenoidal resection of pituitary tumor. In: The M. D. Anderson Guide to Anesthesia for Neurosurgical Cases. Ed(s) Srejic U, DeMonte F. AuthorHouse: Bloomington, 52-63, 2008.
16. Rao G, Klimo P Jr, McCutcheon IE, Mendel E. Development and maturation of the axial skeleton: developmental abnormalities of the cervical spine. In: Spine Trauma: Adult and Pediatric. Ed(s) Kim DH, Ludwig SC, Vaccaro AR, Chang J-C. Elsevier: Philadelphia, 475-488, 2008.
17. McCutcheon IE. Image guided craniotomy for brain tumor. In: Textbook of Stereotactic and Functional Neurosurgery, 2nd. Ed(s) Gildenberg PL, Lozano AM, Tasker R. Springer-Verlag: Berlin, 698-724, 2009.
18. McCutcheon IE. Meningitis and encephalitis. In: Youmans Neurological Surgery, 6th. Ed(s) Winn HR. Elsevier: Philadelphia, 600-611, 2011.
19. St. Clair E, McCutcheon IE. Tumors of the skull. In: Youmans Neurological Surgery, 6th. Ed(s) Winn HR. Elsevier: Philadelphia, 1666-1691, 2011.
20. McCutcheon IE. Neurosurgical malignancies: treating tumors of brain, spine, and peripheral nerve and their effects on the nervous system. In: The M.D. Anderson Surgical Oncology Handbook, 5th. Ed(s) Feig BW, Ching CW. Lippincott Williams & Wilkins: Philadelphia, 686-746, 2012.
21. Kahn L, Raghunathan A, Nader R, Gasco J, McCutcheon IE. Neuro-oncology: basic concepts. In: The Essential Neurosurgery Companion. Ed(s) Gasco J, Nader R. Thieme: New York, 387-392, 2012.
22. Kahn L, Raghunathan A, Nader R, Gasco J, McCutcheon IE. Brain tumors. In: The Essential Neurosurgery Companion. Ed(s) Gasco J, Nader R. Thieme: New York, 392-468, 2012.
23. Kahn L, Raghunathan A, Nader R, Gasco J, McCutcheon IE. Spinal tumors. In: The Essential Neurosurgery Companion. Ed(s) Gasco J, Nader R. Thieme: New York, 469-478, 2012.
24. Ahmed O, McCutcheon IE. Phakomatoses and neurocutaneous disorders. In: The Essential Neurosurgery Companion. Ed(s) Gasco J, Nader R. Thieme: New York, 479-495, 2012.
25. Khursheed F, Barber S, Nader R, Gasco J, McCutcheon IE. Neuroendocrine disorders. In: The Essential Neurosurgery Companion. Ed(s) Gasco J, Nader R. Thieme: New York, 521-543, 2012.
26. Muns JA, Barber S, Nader R, Gasco J, McCutcheon IE. Pituitary surgery. In: The Essential Neurosurgery Companion. Ed(s) Gasco J, Nader R. Thieme: New York, 544-575, 2012.
27. McCutcheon IE. Spinal canal infections. In: Neurosurgical Infectious Disease: Surgical and Nonsurgical Management. Thieme: New York, 163-181, 2013.
28. McCutcheon IE. Pituitary tumors. In: UICC Manual of Clinical Oncology. Wiley-Blackwell Health Sciences: London. In Press.

Manuals, Teaching Aids, Other Teaching Publications

1. McCutcheon IE. Management of pituitary tumors: The clinician’s practical guide. 6, 2. Ed(s) Powell MP, Lightman SL, Laws ER Jr, 75-6, 1/2004.

Last updated: 1/31/2014