Jeffrey S. Wefel, PhD, ABPP
Department of Neuro-Oncology, Division of Cancer Medicine
About Dr. Jeffrey S. Wefel
Dr. Wefel is a board certified neuropsychologist, Professor with Tenure, and Neuropsychology Section Chief in the Department of Neuro-Oncology. He maintains an active consultation-liaison service where he conducts comprehensive neuropsychological assessments, presurgical fMRI of higher order cognitive function for neurosurgical planning, and offers interventions to adult cancer patients suffering from the central nervous system effects of cancer, cancer treatment, or other illnesses. He provides clinical and research mentoring as a Program Supervisor within the Neuropsychology Postdoctoral Fellowship program and hold an appointment as an Adjunct Clinical Assistant Professor in the Clinical Psychology graduate program at the University of Houston where he is involved in the training of Neuropsychology graduate students. Dr. Wefel's research activities seek to characterize the prevalence, pattern, course, risks, and biologic and neural substrates for the development of neurocognitive dysfunction associated with cancer and cancer therapies. Ultimately, this will lead to identification and testing of interventions to prevent and/or minimize cognitive dysfunction. He is the neurocognitive study chair on numerous cooperative group, industry sponsored and investigator initiated trials involving patients with breast cancer, brain tumor and brain metastasis, many of which integrate cognitive and neuroimaging outcomes as well as exploration of genetic moderators of cognitive and brain outcomes.
Present Title & Affiliation
Primary Appointment
Professor with Tenure, Department of Neuro-Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor with Tenure, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Section Chief, Section of Neuropsychology, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Adjunct Associate Professor, Department of Psychology, University of Houston, Houston, TX
Dual/Joint/Adjunct Appointment
Professor with Tenure, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Professor with Tenure, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Adjunct Associate Professor, Department of Psychology, University of Houston, Houston, TX
Education & Training
Degree-Granting Education
| 2002 | University of Houston, Houston, Texas, US, Clinical Psychology, Ph.D |
| 2000 | University of Houston, Houston, Texas, US, Psychology, MA |
| 1994 | Valparaiso University, Valparaiso, Indiana, US, Psychology, BS |
Postgraduate Training
| 2002-2004 | Fellow, Clinical Neuropsychology, UT MD Anderson Cancer Center, Houston, Texas |
| 2001-2002 | Intern, Clinical Neuropsychology, University of Chicago Medical Center, Chicago, Illinois |
Licenses & Certifications
| 2011 | American Board of Professional Psychology, Board Certified in Clinical Neuropsychology |
| 2004 | Texas State Board of Examiners of Psychologists |
Experience & Service
Faculty Academic Appointments
Associate Professor with Tenure, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - 2021
Associate Professor with Tenure, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2021
Assistant Professor, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2006 - 2012
Instructor, Department of Neuro-Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 2005 - 2006
Administrative Appointments/Responsibilities
Neurotoxicity Theme Director, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2025 - Present
Neurobehavioral Health Theme Director, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2025 - Present
Section Chief, Section of Neuropsychology, Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - Present
Other Professional Positions
Co-Chair, Response Assessment in Neuro-Oncology - Cognitive Outcomes Group, 2025 - Present
Consultant, Global Coalition for Adaptive Research, 2024 - Present
Consultant, Astellas/IQVIA, 2024 - Present
Content Committee Member, NBTS Research Roundtable for Clinical Outcome Assessments, 2023 - 2024
Consultant, Boston Scientific, 2023 - Present
Consultant, Astra Zeneca, 2023 - Present
Consultant, Intra-Cellular Therapies, Inc, 2023 - Present
Chair, NRG Brain Tumor Committee Neurocognitive Function Expert Working Group, 2022 - Present
Consultant, Stemline Therapeutics Inc, 2022 - 2023
Consultant, National Cancer Institute, Division of Cancer Prevention, 2021 - 2022
Scientific Advisory Board Member, The Brain Tumour Charity, The Cannabinoid Clinical Trial Scientific Advisory Board, 2021 - 2021
Internal Advisory Board Member, Center for Advanced Biomedical Imaging, The University of Texas MD Anderson Cancer Center, 2021 - Present
Clinical Advisory Committee Member, American Brain Tumor Association, 2020 - Present
Dirk Bakker Visiting Professorship Chair of Neuropsychology in The Netherlands, Neuropsychology Netherlands Foundation, Amsterdam University Medical Centers, Amsterdam, 2019 - 2024
Chief Scientific Advisor, Korysso Therapeutics, Inc, 2018 - 2021
International Scientific Advisory Board Member, Danish Cancer Society National Center for Breast Cancer Survivorship, 2018 - Present
Content Committee Member and Panelist, FDA and NBTS Workshop on Product Development for CNS Metastases, 2018
Member, RTOG/NRG Oncology Brain Tumor Executive Committee, 2018 - Present
Member, RTOG-Patient Centered Outcome Research Executive Committee, 2018 - Present
Consultant, Blueprint Medicines, Inc, 2018 - 2019
Member, National Brain Tumor Society, Research Roundtable - Streamlining Clinical Trials to Accelerate Brain Tumor Drug Development, 2017
Co-Chair, International Neuropsychological Society Oncology Special Interest Group, 2017 - 2020
Independent Scientific Reviewer, Vanquish Oncology, 2016 - 2021
Consultant, Novocure, 2016 - Present
Consultant, Juno Therapeutics, 2015 - Present
Consultant, Acerta Pharma, 2015 - 2016
Scientific Advisory Board, AbbVie, 2015 - Present
Member, Texas Medical Center Regenerative Medicine Consortium, 2015 - 2020
Scientific Advisory Board, Threshold Pharmaceuticals, Inc, 2015 - Present
Scientific Advisory Board, Bayer Pharma AG, 2015 - Present
Member, European Organization for Research and Treatment of Cancer, Survivorship Initiative, 2014 - Present
Member, Alliance for Clinical Trials in Oncology, 2013 - Present
Consultant, Angiochem Corporation, 2013 - 2025
Consultant, Angiochem Corporation, 2013 - Present
Steering Committee on Clinical Trials Endpoints Member, National Brain Tumor Society, 2012 - Present
Medical Advisory Board Member, National Brain Tumor Society, 2012 - Present
Consultant, Actelion, 2012 - 2014
Subject Matter Expert Reviewer, Lance Armstrong Foundation, 2011
Scientific Advisory Board, NeuroCog Trials, 2011 - 2012
Consultant, Geron Corporation, 2011 - 2013
Scientific Advisor, Eli Lilly, 2010 - 2015
Chair, RTOG 0834/EORTC 26053 22054 and NCCTG N0577: CATNON/CODEL Neurocognitive Function and Quality of Life Oversight Committee, 2009 - Present
ODAC Neuropsychology Expert and Advisor, Genentech, Inc, 2009
Member, NCI/CTEP Brain Metastasis in Breast Cancer Working Group, 2009 - Present
Scientific Advisory Board, Genentech, Inc, 2009 - 2016
Consultant, F. Hoffman-La Roche Ltd, 2009 - Present
Consultant, Exelixis, Inc, 2009 - 2010
Member, Response Assessment in Neuro-Oncology Group, 2008 - Present
Member, Assessing The Symptoms of Cancer using Patient-Reported Outcomes (ASCPRO) Cognitive Function Task Force, 2007 - 2010
Member, RTOG/NRG Oncology Quality of Life/Neurocognitive Committee, 2007 - Present
Founder and Steering Committee Member, International Cognition and Cancer Task Force, 2006 - Present
Consultant, Genentech, Inc, 2006 - 2009
Consultant, Pharmacyclics, Inc, 2005 - 2007
Consultant, Linse-Bock Foundation (Grant 2A1291), 2004 - 2006
Extramural Institutional Committee Activities
Member, Patient Centered Outcomes Research Committee, NRG Oncology, 2026 - 2029
Member, Brain Tumor Core Committee, The University of Texas MD Anderson Cancer Center, 2026 - 2029
Core Committee Member, NRG Oncology Brain Tumor Committee, The University of Texas MD Anderson Cancer Center, 2026 - 2028
Advisory Board Member, NeuroAct Advisory Board, The University of Alabama at Birmingham, 2025 - Present
Board Member, Neuroscience in Cancer Advisory Board, NEUROACT (Neuroscience and Cancer Treatment: Advancing Collaborative Translational Research), the University of Alabama at Birmingham (UAB) School of Nursing, 2025 - Present
Neurotoxicity Theme Leadership Team Member, Cancer Neuroscience Program, The University of Texas MD Anderson Cancer Center, 2022 - 2025
Core Leadership Team Member, Neural Health Initiative, The University of Texas MD Anderson Cancer Center, 2019 - Present
Co-Chair, Psychology Credential Committee, The University of Texas MD Anderson Cancer Center, 2018 - Present
Member, Credentials Committee of The Medical Staff, The University of Texas MD Anderson Cancer Center, 2018 - Present
Member, Department of Neuro-Oncology Executive Group, The University of Texas MD Anderson Cancer Center, 2017 - Present
Office of Cancer Survivorship Faculty Reviewer, "NCCN Cognitive Function Guidelines", The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, Brain and Spine Center Patient Care Team, The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, Brain Tumor Center Executive Committee, The University of Texas MD Anderson Cancer Center, 2015 - Present
Member, Patient and Provider Outcomes Development Project (MPPOD), The University of Texas MD Anderson Cancer Center, 2015 - Present
Office of Cancer Survivorship Faculty Reviewer, "NCCN Survivorship Guidelines - Cognitive Function", The University of Texas MD Anderson Cancer Center, 2015 - Present
Member, Psychologist Working Group, The University of Texas MD Anderson Cancer Center, 2015 - Present
Work Group Faculty, “Brain Metastasis greater than 3 Lesions”, The University of Texas MD Anderson Cancer Center, 2014 - Present
Work Group Faculty, “Leptomeningeal Metastases”, The University of Texas MD Anderson Cancer Center, 2014 - Present
Work Group Faculty, “Brain Metastasis (1-3) Lesions”, The University of Texas MD Anderson Cancer Center, 2014 - Present
Work Group Faculty, “Primary Brain Lesion-Diffuse Glioma-Adult”, The University of Texas MD Anderson Cancer Center, 2014 - Present
Member, Psychosocial Council, The University of Texas MD Anderson Cancer Center, 2013 - 2019
Member, Survivorship Research Advisory Workgroup, The University of Texas MD Anderson Cancer Center, 2012 - Present
Member, Gliogene Biospecimen Utilization Committee, The University of Texas MD Anderson Cancer Center, 2012 - Present
Member, Search Committee for Department of Neuro-Oncology Neurophysiology Faculty Member, The University of Texas MD Anderson Cancer Center, 2011
Member, Brain and Spine Center Operations Committee, The University of Texas MD Anderson Cancer Center, 2011 - Present
Alternate Member, Credentials Committee of The Medical Staff, The University of Texas MD Anderson Cancer Center, 2010 - 2012
Member, Faculty Senate, The University of Texas MD Anderson Cancer Center, 2010 - 2016
Member, Cancer Survivorship Psychosocial Research Work Team, The University of Texas MD Anderson Cancer Center, 2007 - 2019
Member, Psychosocial Behavioral and Health Services Research Committee, The University of Texas MD Anderson Cancer Center, 2006 - 2009
Editorial Activities
Executive Editor, Neuro-Oncology Practice, 2013 - 2020
Editorial Board, Neuro-Oncology, 2013 - 2015
Co-Editor, Neuro-Oncology, Vol 14, Suppl 4, 2012
Honors & Awards
| 2016 | Finalist, Faculty Achievement Award - Clinical Research, The University of Texas M. D. Anderson Cancer Center |
| 2015 | Finalist, Robert M. Chamberlain Distinguished Mentor Award, The University of Texas M. D. Anderson Cancer Center |
| 2004 - 2006 | Clinical Research Loan Repayment Program, National Institutes of Health |
| 2002 - 2003 | Muriel D. Lezak Research Award, The Houston Neuropsychological Society |
| 2001 | Shell Foundation Graduate Scholarship, University of Houston |
| 1998 | Clinical Neuropsychology Track Student Representative, University of Houston |
| 1996 | Stella E. Cullen Scholarship, University of Houston |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2025. Neuropsychology in Neuro-Oncology: From Clinic to Clinical Trials. Invited. Presented at MDACC Neuro-Oncology Core Curriculum Lecture Series. Houston, Texas, US.
- 2023. Cognitive Function in Patients with Cancer. Invited. Presentation at The University of Houston. Houston, Texas, US.
- 2023. Neuropsychology of Neuro-Oncology. Neuropsychology Grand Rounds. Houston, Texas, US.
- 2023. A Review of Neuropsychological Sequelae of Cancer and Cancer Therapy. MDACC Neuro-Oncology Core Curriculum Lecture Series. Houston, Texas, US.
- 2020. Neuropsychology of Oncology - Part II. Neuropsychology Grand Rounds. Houston, Texas, US.
- 2020. Neuropsychology of Oncology - Part I. Neuropsychology Grand Rounds. Houston, Texas, US.
- 2017. Maximizing Cognitive Function. Together in Hope: A Conference for Brain Tumor Patients and Their Families. Houston, TX, US.
- 2017. Understanding and Maximizing Cognitive Function as a Cancer Survivor. Conference. PICNIK Presentation. Houston, TX, US.
- 2016. Understanding and Maximizing Cognitive Function as a Cancer Survivor. Cancer Survivorship Conference. Houston, TX, US.
- 2016. A Brain-Plasticity Based Computerized Intervention to Treat Attention and Memory Problems in Adult Brain Tumor Survivors. 2016 Survivorship Research Symposium. Houston, TX, US.
- 2015. "Chemobrain". Conference. Presented at the Breast Friends Support Group and Education Program. Houston, TX, US.
- 2014. A brain-plasticity based computerized intervention to treat attention and memory problems in adult brain tumor survivors. Cancer Survivorship Research Symposium. Houston, Texas, US.
- 2013. Chemobrain. Houston, TX, US.
- 2013. Neuropsychological Changes and Interventions in Head & Neck Patients. Conference. Bay Area RCC Lecture Series. Houston, TX, US.
- 2013. Cognition Neurotoxicity in Breast Cancer. Conference. Translational Breast Cancer Research Consortium. Houston, TX, US.
- 2013. Maximizing Cognitive Function. Methodist Hospital NeuroCircle Brain Tumor Support Group. Houston, Texas, US.
- 2013. Neuropsychological Functioning in Patients with Cancer. Houston, TX, US.
- 2012. Neuropsychological Functioning in Patients with Brain Tumors. Houston, TX, US.
- 2012. Cognitive Function in RTOG 0525: Prognostic Factor and Efficacy Outcome. Houston, TX, US.
- 2011. Clinical and Research Aspects of Cognition and Cancer Cancer. Houston, Texas, US.
- 2011. Maximizing Cognitive Function. Houston, TX, US.
- 2010. Neurocognitive Issues in Brain Mets. Houston Neuropsychological Society. Houston, TX, US.
- 2010. Neurocognitive Decline among Cancer Patients. Houston, Texas, US.
- 2009. Maximizing Cognitive Function. Houston, TX, US.
- 2009. Cognitive Dysfunction Associated with Breast Cancer and Breast Cancer Therapy. Conference. Houston Neuropsychological Society. Houston, TX, US.
- 2009. Neuropsychology: Cognition and Cancer. Functional Brain Anatomy Seminar. Houston, Texas, US.
- 2008. Neuropsychological Outcomes Associated with Radiation Therapy in Brain Tumor Patients. Houston, Texas, US.
- 2007. Cancer and Cancer Treatment Related to Cognitive Dysfunction: From Diagnosis to Survivorship. Houston, TX, US.
- 2007. Functional (Behavioral) Neuroanatomy. Functional Brain Anatomy Seminar. Houston, Texas, US.
- 2006. Neuropsychological Assessment. Department of Neurosurgery. Houston, Texas, US.
- 2006. Cognitive Rehabilitation: A vision for MDACC. Houston, TX, US.
- 2005. Genetic modulation of cognitive function in cancer patients. Houston, TX, US.
- 2005. Toxicity. Houston, TX, US.
- 2004. Chemobrain: Is It Real?. Houston, TX, US.
- 2002. Tamoxifen associated neurotoxicity in women with early breast cancer: Preliminary results of an interim analysis (ID00-425). Houston, TX, US.
- 2001. Psychoneuroendocrinology in Breast Cancer: The Effect of Tamoxifen on Cognitive & Emotional Functioning. Houston, TX, US.
- 2001. Tamoxifen: Potential Mechanisms for Cognitive Dysfunction. Houston, TX, US.
National Presentations
- 2026. Neuro-Psychology in Oncology Session of the Neuro-oncology Track. Invited. 23rd Annual NeuroTech Convention of the Society for Brain Mapping and Therapeutics. Los Angeles, California, US.
- 2025. Evaluating congruence between technology-enabled and traditional learning and memory measures in patients with GBM. Invited. WFNOS/30th Annual Meeting & Education Day. Honolulu, Hawaii, US.
- 2024. Measuring Cognitive Function: How is this done?. Panelist. Developing a Roadmap for Use of Performance-Based Cognitive Function Clinical Outcome Assessments in Neuro-Oncology Clinical Trials for Newly Diagnosed GBM, US.
- 2024. Neuropsychological Outcomes in Patients with Brain Metastasis. Invited. 5th Annual Multidisciplinary CNS Metastases Update, US.
- 2023. Coordinated Care of Brain Metastasis. 2023 San Antonio Breast Cancer Symposium. San Antonio, TX, US.
- 2023. Neurocognitive Testing in Cooperative Group Clinical Trials. SWOG Fall Group Meeting. Chicago, IL, US.
- 2023. Neuropsychological Sequelae of Brain Mets and Their Treatment. 2023 SNO/ASCO Cancer Conference. San Francisco, CA, US.
- 2023. Neurocognitive function and neurocognitive concerns in an ongoing phase III trial of pre-operative SRS versus post-operative SRS for brain metastases. Poster. 2023 SNO/ASCO CNS Cancer Conference. San Francisco, California, US.
- 2023. Panelist, Leptomeningeal Think Tank. Leptomeningeal Think Tank. San Francisco, CA, US.
- 2022. Neuropsychological Sequelae of CNS Cancer and Cancer Therapy. Department of Neurology Grand Rounds Virtual, US.
- 2022. Panelist, NCI Workshop on Shaping the Landscape of Brain Metastases Research. NCI Workshop Virtual, US.
- 2022. Neurocognitive function and neurocognitive concerns in an ongoing phase III trial of pre-operative SRS versus post-operative SRS for brain metastases. Poster. 2023 SNO/ASCO CNS Cancer Conference. san fran, US.
- 2022. Neuropsychiatric Symptoms and How to Manage Them. Invited. Presented at the American Brain Tumor Association Webinar, Virtual, US.
- 2022. An Overview of Cognitive Function in Adult Patients with CNS Cancer. Cancer Control and Survivorship Program and Neurobiology and Brain Tumor Program Seminar. Memphis, TN, US.
- 2022. Cognitive Function. Melanoma Research Foundation/MD Anderson Cancer Center Mastering Melanoma: A Symposium for Patients and Caregivers, Virtual, US.
- 2021. Neuropsychological Sequelae of Brain Mets and Their Treatment. 2nd Annual UW-Madison/MCW Multidisciplinary CNS Metastases Symposium, Virtual, US.
- 2021. Assessing Clinical Benefit in CNS Clinical Trials - Neurocognitive Function (Who, What, Where, When, Why, How?). Annual Conference on CNS Clinical Trials Co-Sponsored by SNO and ASCO, Virtual, US.
- 2021. Glioma Controversies: Patient-Focused Case-Based Discussion. Presented at the 63rd Annual ASTRO Meeting. Chicago, IL, US.
- 2021. Neuropsychological Sequelae of Brain Mets and Their Treatment. Society for Neuro-Oncology Third Annual Conference on Brain Metastases, Virtual, US.
- 2021. Conducting Neurocognitive Clinical Trials in NCORP. NCI Symptom Management Quality of Life Steering Committee - Cancer-Related Cognitive Impairment (CRCI) Clinical Trials Planning Meeting, Virtual, US.
- 2020. CoDEL: Phase III trial of RT alone RT plus TMZ or TMZ alone for newly-diagnosed 1p/19q codeleted anaplastic oligodendroglioma. Analysis from the initial study design (NCCTG N0577, Alliance). 25th Annual Meeting and Education Day of the Society for Neuro-Oncology, Virtual, US.
- 2020. CODEL: Phase II Study of RT Alone, RT Plus Temozolomide, or Temozolomide Alone for Newly-Diagnosed 1P/19Q Codeleted Anaplastic Oligodendroglioma Patients. Updated Analysis from the Initial Study Design. 25th Annual Meeting and Education Day of the Society of Neuro-Oncology, Virtual, US.
- 2020. Neurocognitive function (NCF) of the Photon Cohort in NRG-BN001. 25th Annual Meeting and Education Day of the Society for Neuro-Oncology, Virtual, US.
- 2020. Neurcognitive function (NCF) outcomes of RTOG Foundation 3508: A Phase 3 trial of ABT-414 with concurrent chemoradiation and adjuvant temozolomide in patients with EGFR-amplified newly diagnosed GBM. 25th Annual Meeting and Education Day of the Society for Neuro-Oncology, Virtual, US.
- 2020. Pretreatment volume of MR-determined white matter injury (WMI) predicts neurocognitive decline after hippocampal avoidant (HA) WBRT-Memantine for brain metastases: Secondary analysis of NRG Oncology CC001. 25th Annual Meeting and Educaion Day of the Society for Neuro-Oncology, Virtual, US.
- 2020. Stereotactic radiosurgery versus whole-brain radiation therapy for patients with 4-15 brain metastases: A phase II randomized controlled trial. Invited. American Society for Radiation Oncology (ASTRO) Annual Meeting, US.
- 2020. An Overview of Cognition and Health Related Quality of Life in Adult Brain Cancer Patients. 2020 UCSF Cognition in Brain Cancer Symposium, Virtual, US.
- 2020. How Neuropsychology is Impacting Cancer Care (Continuing Education Course). The 48th Annual Meeting of the International Neuropsychological Society. Denver, CO, US.
- 2019. Neurocognitive function (NCF) and quality of life (QOL) results from a phase II study of temozolomide-based chemoradiotherapy regimen for high risk low-grade gliomas. 2019 Annual Meeting of the Society for Neuro-Oncology. Phoenix, AZ, US.
- 2019. Preservation of neurocognitive function & patient-reported symptoms with hippocampal avoidance (HA) during whole-brain radiotherapy (WBRT) for brain metastases: Long-term results of NRG Oncology CC001. 2019 Annual Meeting of the Society for Neuro-Oncology. Phoenix, AZ, US.
- 2019. Hippocampal avoidance during WBRT for brain metastases better preserves neurocognitive function and patient-reported symptoms, while achieving similar intracranial control and survival. Congress of Neurological Surgeons Annual Meeting. San Francisco, CA, US.
- 2019. Prospective Phase II Randomized Trial Comparing Proton Therapy vs. IMRT for Newly Diagnosed GBM: Secondary Analysis Comparison of Progression Free Survival between Clinical Radiological Assessment vs. Response Assessment in Neuro-Oncology (RANO). 2019 Annual Meeting of the American Society for Radiation Oncology (ASTRO). Chicago, IL, US.
- 2019. Cognitive Effects of Cancer and Cancer treatment Across the Lifespan Workshop. 2019 American Academy of Clinical Neuropsychology. Chicago, IL, US.
- 2019. The neuropsychological sequelae of brain metastases and their treatment. Weill Cornell Brain Metastases Symposium. New York, NY, US.
- 2019. Defining Clinical Benefit in Patients with Brain Mets (Panelist). NBTS-FDA Public Workshop: Product Development for Central Nervous System (CNS) Metastases. Silver Spring, MD, US.
- 2019. Neurocognitive Effects of Cancer and Cancer Therapy. Neurosurgery Grand Rounds. Aurora, CO, US.
- 2018. Cognitive Outcomes in Cancer. Mass General Hospital Grand Rounds and Keynote Lecture of the Frye-Hallloran Symposium. Boston, MA, US.
- 2018. Assessment and Clinical Implications of Cognitive Change in Aging Cancer Survivors. 54th Annual Meeting of the American Society of Clinical Oncology, Education Session: Managing Cognitive Changes in Cancer Survivors. Chicago, IL, US.
- 2017. Cognitive Function in Patients with Brain Tumor. American Brain Tumor Association 2017 Patient & Family Conference. Chicago, IL, US.
- 2017. Cancer-Related Cognitive Impairment: How It's Measured and How Research is Being Translated Into Clinical Fronts. American College of Sports Medicine, Exercise is Medicine. Denver, CO, US.
- 2017. Coping with Behavioral and Cognitive Changes. Conference. Sontag Foundation Brain Tumor Survivorship Conference. Jacksonville, FL, US.
- 2017. Cognitive Function in Patients With Cancer. Oncology Grand Rounds. Jacksonville, FL, US.
- 2017. The Neurocognitive Credentialing Process. NRG Oncology Semiannual Meeting. Philadelphia, PA, US.
- 2016. Cognitive Effects of Radiation. Diagnosis, Mechanisms, and Management of Cancer Treatment-Induced Neurotoxicities: Neuropathy, Fatigue and Cognitive Impairment. Houston, TX, US.
- 2016. Cognitive Functioning. Bayer Advisory Board Meeting. San Francisco, CA, US.
- 2015. ChemobrainThird Biennial “Advances in Survivorship Practice: A Conference for Healthcare Professionals”. Third Biennial “Advances in Survivorship Practice: A Conference for Healthcare Professionals”. Houston, TX, US.
- 2015. Tumor volumetric and textural feature predictors of neurocognitive impairment in patients with temporal lobe glioma. 20th Annual Meeting of the Society for Neuro-Oncology Scientific Meeting. San Antonio, TX, US.
- 2015. Relationships between tumor compartment volumes and neurocognitive functioning in patients with temporal lobe glioma. 20th Annual Meeting of the Society for Neuro-Oncology Scientific Meeting. San Antonio, TX, US.
- 2015. CODEL (Alliance-N0577; EORTC-26081/2208; NRG-1071; NCIC-CEC-2): Phase III randomized study of RT vs. RT+TMZ vs. TMZ for newly diagnosed 1p/19q-codeleted anaplastic glioma. Analysis of patients treated on the original protocol design. 20th Annual Meeting of the Society for Neuro-Oncology Scientific Meeting. San Antonio, TX, US.
- 2015. Cognitive and Personality Changes. The American Brain Tumor Association's 2015 Patient and Family Conference "Providing and Pursuing Answers: Advances in Brain Tumor Research, Treatment & Care". Chicago, IL, US.
- 2014. AVAglio Neurocognitive Substudy Data. American Academy of Neurology 66th Annual Meeting. Philadelphia, PA, US.
- 2013. Longitudinal analysis of neurocognitive outcomes in patients with glioblastoma (GBM) enrolled in RTOG 0825. 4th Quadrennial Meeting of the World Federation of Neuro-Oncology held in conjunction with the Scientific Meeting and Education Day of the Society for Neuro-Oncology. San Francisco, CA, US.
- 2013. Cognitive Neurotoxicity in Oncology. Neurosurgery Grand Rounds. Boston, MA, US.
- 2013. Neurocognitive Testing in RTOG Cooperative Group Trials: Lessons Learned. Invited. Presented at the RTOG Research Associate Education Session. Philadelphia, PA, US.
- 2013. Neurocognitive Function (NCF) Outcomes in Patients with Glioblastoma (GBM) Enrolled in RTOG 0825. 2013 American Society of Clinical Oncology Meeting. Chicago, IL, US.
- 2013. Comparative Impact of Treatment on Patient Reported Outcomes (PROs) in Patients with Glioblastoma (GBM) enrolled in RTOG 0825. 2013 American Society of Clinical Oncology Meeting. Chicago, IL, US.
- 2013. Cognitive Neurotoxicity in Oncology. Massachusetts General Hospital/Harvard Cancer Center Stephen E. and Catherine Pappas Center for Neuro-Oncology. Boston, MA, US.
- 2013. Cognitive Dysfunction Associated with Cancer and Cancer Therapy. International Society for Clinical Trials and Methodology Meeting. Washington, DC, US.
- 2012. Memantine for the Prevention of Cognitive Dysfunction in Patients Receiving Whole-Brain Radiotherapy (WBRT): First Report of RTOG 0614, a Placebo-Controlled, Double-Blind, Randomized Trial. 17th Annual Scientific Meeting of the Society for Neuro-Oncology. Washington, DC, US.
- 2012. Neurocognitive Testing in RTOG Clinical Trials. 2012 RTOG Semiannual Meeting, RTOG Research Associate Education Session. Philadelphia, PA, US.
- 2012. NCI Integrative Data Analysis Meeting. National Cancer Institute. Bethesda, MD, US.
- 2012. Introduction to Neurocognitive Testing. Quality of Life and Neurocognitive Studies in RTOG: Achievements and Challenges. RTOG Semi-annual Meeting. Philadephia, PA, US.
- 2011. Prediction of memory outcomes after resection of high grade glioma. 16th Annual Scientific Meeting of the Society for Neuro-Oncology. Garden Grove, CA, US.
- 2011. Clinical Utility of Quality of Life (QOL) and Symptom Assessment as Prognostic Factors for Survival and Measures of Treatment Effects on RTOG 0525. Invited. 2011 Society for Neuro-Oncology Meeting in Collaboration with the AANS/CNS Section on Turmors. Garden Grove, CA, US.
- 2011. Clinical utility of neurocognitive function as a prognostic factor for survival and measure of differential between-arm treatment effects on RTOG-0525. 16th Annual Scientific Meeting of the Society for Neuro-Oncology. Garden Grove, CA, US.
- 2011. Clinical Utility of Neurocognitive Function (NCF), Quality of Life (QOL) and Symptom Assessment as Prognostic Factors for Survival and Measures of Treatment Effects on RTOG 0525. 2011 Annual Meeting of the American Society of Clinical Oncology. Chicago, IL, US.
- 2011. A Randomized Phase III Trial Comparing Standard Adjuvant Temozolomide (TMZ) with a Dose-Dense (dd) Schedule in Newly Diagnosed Glioblastoma (GBM) on RTOG 0525. 2011 Annual Meeting of the American Society of Clinical Oncology. Chicago, IL, US.
- 2011. Progress in Understanding and Addressing the Impact of Cancer Treatment on Cognitive Functioning. 32nd Annual Meeting and Scientific Sessions of the Society of Behavioral Medicine. Washington, DC, US.
- 2011. Neurocognitive Outcomes in Patients with Brain Metastases. Breast Oncology Seminar Series. Boston, MA, US.
- 2011. Neurocognitive Testing in RTOG Clinical Trials. 2011 RTOG Semiannual Meeting, RTOG, QOL and Neurocognitive Function Workshop: Quality of Life and Neurocognitive Studies in RTOG: Achievements and Challenges. Atlanta, GA, US.
- 2010. Assessment of Neuropsychological Function: From Clinical Practice to Clinical Trials. Invited. Presented at the 6th Annual Chicago Supportive Oncology Conference. Chicago, IL, US.
- 2010. Quality of Life Workshop. National Brain Tumor Society. San Francisco, CA, US.
- 2010. An overview of the clinical and research aspects of cognition and cancer. International Cognition and Cancer Task Force Meeting. New York, NY, US.
- 2009. Chemobrain? Impact of Tumor and Treatment on Neurocognitive Function: What We Know, Where to Go. 2009 Joint Meeting of the Society for Neuro-Oncology and AANS/CNS Section on Tumors. New Orleans, LA, US.
- 2009. Patient and Caregiver Congruence in Symptom Report and Association with Patient Neurocognitive Status. 2009 Joint Meeting of the Society for Neuro-Oncology and AANS/CNS Section on Tumors. New Orleans, LA, US.
- 2009. Neurocognitive Function in Patients with Glioblastoma at First or Second Relapse Treated with Bevacizumab Alone or in Combination with Irinotecan in the BRAIN Study. 2009 Joint Meeting of the Society for Neuro-Oncology and AANS/CNS Section on Tumors. New Orleans, LA, US.
- 2009. A Randomized Phase III, Double Blind, Placebo-Controlled Trial of Memantine for Prevention of Cognitive Dysfunction in Patients Receiving Whole Brain Radiotherapy. RTOG Semi-annual Meeting. Philadelphia, PA, US.
- 2009. Neurocognitive function in patients with glioblastoma multiforme in first or second relapse treated with bevacizumab in the BRAIN study. 2009 Annual Meeting of the American Society of Clinical Oncology. Chicago, IL, US.
- 2009. Neurocognitive Testing in Multicenter Clinical Trials. Brain Metastases in Breast Cancer Workshop. Pentagon City, VA, US.
- 2009. Cognitive Impairment in Cancer Patients. 2009 Scripps Cancer Center's 29th Annual Conference: Clinical Hematology & Oncology. San Diego, CA, US.
- 2008. Neurocognitive Function and Quality of Life. 2008 Annual Meeting of the Society for Neuro-Oncology. Lake Las Vegas, NV, US.
- 2008. The Effect of 'Lesion Momentum' on Neurocognitive Function in Primary Brain Tumor Patients. Invited. Presented at the 2008 Annual Meeting of the Society for Neuro-Oncology. Lake Las Vegas, NV, US.
- 2008. Cancer and cancer-therapy related cognitive dysfunction. Population Sciences Grand Rounds. Tampa, FL, US.
- 2008. Cognitive Impairment. Invited. Mechanisms and Treatment of Cancer-Related Symptoms Conference. Houston, TX, US.
- 2007. Cancer and cancer-therapy related cognitive dysfunction. Psychiatry Grand Rounds. New York, NY, US.
- 2007. Role and relevance of neurocognitive testing in clinical trials. CRA Plenary Sessions Southwest Oncology Group Annual Meeting. Huntington Beach, CA, US.
- 2007. Cognitive effects of Chemotherapy. International Neuropsychological Society 35th Annual Meeting. Portland, OR, US.
- 2007. Neurocognitive Impairment Following Chemotherapy. International Neuropsychological Society 35th Annual Meeting. Portland, OR, US.
- 2007. Evaluation of Functional Magnetic Resonance Imaging, Relative Cerebral Blood Volume and Neuropsychological Testing in patients with 1-3 Brain Metastases Treated with Stereotactic Radiosurgery +/- Whole Brain Radiation. International Neuropsychological Society 35th Annual Meeting. Portland, OR, US.
- 2006. Chemobrain: Is it real?. Northwestern University Center for Outcomes Research and Education. Chicago, IL, US.
- 2006. Neurocognitive Outcomes in Patients Treated with Focal or Whole Brain. Radiation Therapy2006 Annual Meeting of the American Society of Clinical Oncology. Chicago, IL, US.
- 2006. Assessment of Cognitive Function. Committee on Special Populations, Southwest Oncology Group Annual Meeting. Salt Lake City, UT, US.
- 2006. Neurocognitive sequelae of adult cancer and intervention strategies at MD Anderson. National Coalition for Cancer Survivorship Conference. Houston, TX, US.
- 2006. Cancer, Chemotherapy and MCI. 4th Annual Mild Cognitive Impairment (MCI) Symposium. Miami, FL, US.
- 2005. Genetic modulation of cognitive function in cancer patients. Mechanism and Treatment of Cancer Related Symptoms. Houston, TX, US.
- 2004. APOE genotype and cognitive function in brain tumor patients diagnosed with malignant glioma. 32nd annual meeting of the International Neuropsychological Society. Baltimore, MD, US.
- 2003. Cognitive dysfunction in breast cancer patients: a prologue Cognitive Problems Associated with Chemotherapy for Cancer. Houston, TX, US.
International Presentations
- 2026. Princess Margaret Seminar. Invited. Princess Margaret Cancer Centre. Toronto, CA.
- 2025. Workshop 3: Neurospychology. Invited. IX Neuro-Oncology Conference 2025. Santiago, CL.
- 2025. Cognitive impairment in brain metastases patients. Invited. IX Neuro-Oncology Conference 2025:. Santiago, CL.
- 2025. Survivorship Abstracts Session. Invited. 2025 WFNOS and SNO Annual Meeting. Honolulu, US.
- 2025. Preventing Late Cognitive Effects of Anti-Tumor Treatments. Invited. European Association of Neuro-Oncology Educational Day 2025. Prague, CZ.
- 2025. Session 6: Neurobehavioral Health. Invited. 2026 International Cancer Neuroscience Symposium. Houston, US.
- 2025. Session 2: Neurotoxicity. Invited. 2026 International Cancer Neuroscience Symposium. Houston, US.
- 2025. The Effects Of Cancer And Treatment On The CNS. Invited. North American Skull Base Society 2025 Annual Meeting. New Orleans, US.
- 2025. Neuropsychological Outcomes Following Resection Of Anterior Skull Base Meningiomas. Invited. North American Skull Base Society 2025 Annual Meeting. New Orleans, US.
- 2024. Neuropsychology in Neuro-Oncology: From Clinic to Clinical Trials. Visiting. Groningen, NL.
- 2024. Cancer and Cognition. Visiting. Dirk J. Bakkerleerstoel Masterclass. Amsterdam, NL.
- 2023. Neurological complications of cancer therapy. Invited. 2023 Society for Neuro-Oncology Annual Scientific Meeting. Vancouver, CA.
- 2023. Baseline patient-reported outcomes in an ongoing phase III trial of pre-operative SRS versus post-operative SRS for brain metastases. 28th Annual Meeting of the Society for Neuro-Oncology. Vancouver, British Columbia, CA.
- 2023. Changes in functional connectivity after surgery are associated with decline in functional independence in patients with eloquent glioma. 28th Annual Meeting of the Society for Neuro-Oncology Scientific Meeting. Vancouver, British Columbia, CA.
- 2023. Variability in anxiety and depression symptoms after eloquent glioma resection is associated with changes in functional connectomic properties. 28th Annual Meeting of the Society for Neuro-Oncology Scientific Meeting. Vancouver, British Columbia, CA.
- 2023. Neuropsychological Sequelae of Non-CNS Cancer and Cancer Therapy. 36th European College of Neuropsychopharmacology Congress. Barcelona, ES.
- 2023. Neurocognition and Rehabilitation in Brain Metastases. 11th Edition of Brain Metastases Research and Emerging Therapy Conference. Paris, FR.
- 2021. Neuroimaging Advances in Cancer Related Cognitive Impairment Lessons Learned from Supportive Care. Multinational Association of Supportive Care in Cancer/International Society for Oral Oncology Annual Meeting. Seville, ES.
- 2021. Neurocognitive Aspects of Neuro-Oncology: An Update Presented at A Multidisciplinary Approach towards Brain and Spine Tumors. Clinica Alemana. Vitacura, CL.
- 2020. Cognition Function in Patients with Cancer. Master Program in Advanced Neuropsychology. Utrecht, NL.
- 2020. Neuroimaging Advances in Cancer Related Cognitive Impairment: Lessons Learned for Supportive Care. Multinational Association of Supportive Care in Cancer (delayed due to COVID-19), Virtual, ES.
- 2019. Metastases and Neurocognitive Function: An Update. 14th International Stereotactic Radiosurgery Society Congress. Rio de Janeiro, BR.
- 2018. Chemobrain and Beamobrain, Neuro-Oncology Course. Institute of Education and Research of the Sirio-Libanes Hospital. San Paulo, BR.
- 2018. Cancer-Related Cognitive Impairment: From Assessment to Treatment. Cancer and Cognition Seminar, HK.
- 2018. "Chemobrain" and Beamobrain" in Patients with Glioma: How Real Is It?. The Society for Neuro-Oncology Latin American (SNOLA) 2018 Annual Meeting. San Paulo, BR.
- 2018. Cognitive Evaluation in Neuro-Oncology: How Useful?. The Society for Neuro-Oncology Latin America (SNOLA) 2018 Annual Meeting. San Paulo, BR.
- 2018. Cognitive Outcomes in Patients with Brain Tumor. 19th International Leksell Gamma Knife Society Meeting. Dubai, AE.
- 2017. Maximizing Cognitive Function. Michael Rossman Brain Tumour Lectureship. Toronto, CA.
- 2017. Maintaining Cognitive Function in Patients with CNS Metastases Receiving Multimodality Treatment. 7th Annual Brain Metastases Research and Emerging Therapy Conference. Marseilles, FR.
- 2017. Maintaining Cognitive Function in Patients with Brain Metastases. Brain Sciences Rounds, Sunnybrook Health Sciences Center. Toronto, CA.
- 2017. Cognitive Deterioration in Patients with Brain Metastases: Tumor or Treatment?. 5th Quadrennial Meeting of the World Federation of Neuro-Oncology Societies. Zurich, CH.
- 2016. Cognitive Function: Impact of Medical Therapies. 12th Meeting of the European Association of Neuro-Oncology (EANO). Mannheim, DE.
- 2016. Cognitive Function in Adult Cancer Patients. 2016 Chinese Psycho-Oncology Society Meeting. Hunan, CN.
- 2015. Cancer and Cognition: The Neuropsychology of CNS and non-CNS Cancer and Cancer Treatments - Current State of the Science. Aarhus University. Aarhus, DK.
- 2015. QOL Controversies With Anti-Angiogenic Therapy. 2015 Current Trends in the Management of Malignant Gliomas: New Horizons in the Treatment of Brain Tumors. Xi'an, CN.
- 2015. Neurocognitive Outcomes in Brain Tumor Patients. 2015 Current Trends in the Management of Malignant Gliomas: New Horizons in the Treatment of Brain Tumors. Xi'an, CN.
- 2013. Longtiudinal analysis of neurocognitive outcomes in patients with glioblastoma (GBM) enrolled in RTOG 0825. Invited. Oral Presentation at the 4th Quadrennial Meeting of the World Federation of Neuro-Oncology held in conjunction with the Scientific Meeting and Education Day of the Society for Neuro-Oncology. San Francisco, US.
- 2013. Neuropsychological Functioning in Patients with Brain Tumor. International Neuropsychological Society 2013 Mid-Year Meeting. Amsterdam, NL.
- 2010. Concurrent and Criterion Validity Related Evidence for the Neurocognitive Function Clinical Trial Battery in Brain Tumor Patients. 2010 Annual Meeting of the Society for Neuro-Oncology. Montreal, CA.
- 2010. Maximizing Cognitive Function. Brain Tumour Awareness, A Mini Symposium. Toronto, CA.
- 2006. Mechanisms of Cognitive Dysfunction after Chemotherapy. 8th World Congress of Psycho-Oncology Meeting. Venice, IT.
- 2002. Central Effects of Non-CNS Therapeutic Radiation for Cancer. The Effects of Radiotherapy on Brain and Behavior Through the Lifespan. San Juan, PR.
- 2002. Differential Effects of Radiation Schedule on Long Term Outcome in Adults. The Effects of Radiotherapy on Brain and Behavior Through the Lifespan. Puerto Rico, PR.
Formal Peers
- 2025. Cognitive Function in Patients with Cancer Cognitive Disorder and Lifespan Neuropsychology: Assessment/Applications III. Houston, Texas, US.
- 2024. Cognitive Function in Patients with Cancer Cognitive Disorder and Lifespan Neuropsychology: Assessment/Applications III, US.
- 2023. Cognitive Function in Patients with Cancer Cognitive Disorder and Lifespan Neuropsychology: Assessment/Applications III. Invited, US.
- 2023. A Review of Neuropsychological Sequelae of Cancer and Cancer Therapy. Invited, US.
- 2022. Cognitive Function in Patients with Cancer Cognitive Disorder and Lifespan Neuropsychology: Assessment/Applications III. Invited, TX, US.
- 2022. An Overview of Cognitive Function in Adult Patients with CNS Cancer. Invited, US.
- 2022. Neuropsychological Sequelae of CNS Cancer and Cancer Therapy. Invited, TX, US.
- 2021. Cognitive Function in Patients with Cancer Cognitive Disorder and Lifespan Neuropsychology: Assessment/Applications III. Invited, TX, US.
- 2016. Neuropsychological Functioning in Adult Cancer Patients Cognitive Disorder and Lifespan Neuropsychology: Assessment/Applications III. Invited, TX, US.
- 2014. Neuropsychological Functioning in Adult Cancer Patients Cognitive Disorder and Lifespan Neuropsychology: Assessment/Applications III. Invited, TX, US.
- 2001. Cerebellar Clinical Neuroanatomy. Invited. Chicago, IL, US.
- 1998. Donepezil: Implications for the assessment of the Alzheimer's patient. Invited. Houston, TX, US.
Grant & Contract Support
| Date: | 2026 - 2028 |
| Title: | Multimodal Biomarker Signatures of Cognitive Dysfunction in ICITreated Patients with Melanoma |
| Funding Source: | DOD - Melanoma Research Program Survivorship Research Award |
| Role: | Co-PI |
| ID: | HT942525PCRPIDA |
| Date: | 2026 - 2028 |
| Title: | Novel PPARβ Agonist Offers Therapeutic Targeting of the Qki-PPAR-RXR Complex for the Treatment of Chemotherapy-Induced Cognitive Impairment |
| Funding Source: | American Cancer Society |
| Role: | Mentor |
| ID: | FP00024283_Res1 |
| Date: | 2026 - Present |
| Title: | Mapping the Structural and Functional Neuroarchitecture of Glioblastoma to Predict Survival and Cognitive-Emotional Outcomes |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2025 - 2030 |
| Title: | Brain Biomarkers for Chemotherapy-Induced Neurotoxicity in Breast Cancer |
| Funding Source: | Stephen I. Katz Early Investigator Research Project Grant R01, NIH |
| Role: | Co-I |
| Date: | 2024 - 2025 |
| Title: | Brain and Biofluid Biomarkers underlying Cognitive Following Immune Checkpoint Inhibitor Therapy in Patients with Metastatic Melanoma |
| Funding Source: | Cancer Neuroscience Program Grant The University of Texas MD Anderson Cancer |
| Role: | PI |
| Date: | 2024 - 2025 |
| Title: | Characterization and prediction of 2nd-generation anti androgen associated neurotoxicity in patients with prostate cancer |
| Funding Source: | Cancer Neuroscience Program Grant, The University of Texas MD Anderson Cancer Center |
| Role: | Co-PI |
| Date: | 2024 - 2029 |
| Title: | RESCuE: Resetting microenvironmental interaction in the nervous System after Chemotherapy Exposure |
| Funding Source: | CRUK/NCI Cancer Grand Challenges |
| Role: | Co-I |
| Date: | 2023 - 2024 |
| Title: | Development of a rodent neurobehavioral core to assess treatment-related toxicities, mechanism-based drug targets, and therapeutics |
| Funding Source: | Cancer Neuroscience Program Grant, The University of Texas MD Anderson Cancer |
| Role: | Co-PI |
| Date: | 2022 - 2027 |
| Title: | A Comprehensive Clinical fMRI Software Solution to Enable Mapping of Critical Functional Networks and Cerebrovascular Reactivity in the Brain |
| Funding Source: | NIH/NCI |
| Role: | Consult |
| ID: | 5R01CA258788-04 |
| Date: | 2021 - 2024 |
| Title: | A virtually delivered exercise intervention to mitigate cognitive deficits from radiotherapy in AYAs with brain tumors |
| Funding Source: | Institutional Research Grant Program The University of Texas MD Anderson Cancer Center |
| Role: | Co-I |
| Date: | 2021 - 2024 |
| Title: | Mechanistic impact of demyelination on cognitive dysfunction following chemotherapy and surgery for breast cancer |
| Funding Source: | MD Anderson Cancer Center Multidisciplinary Research Program |
| Role: | Co-PI |
| Date: | 2021 - 2026 |
| Title: | A Phase 3 Randomized Controlled Trial of Post-Surgical Stereotactic Radiotherapy (SRT) versus Surgically Targeted Radiation Therapy (STaRT) with Gamma Tile for Treatment of Newly Diagnosed Metastatic Brain Tumors |
| Funding Source: | GT Medical Technology, Clinical Trial Contract |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2020 - 2025 |
| Title: | Real Time Integrated Neurocognitive Function Study Comparing Neurocognitive Function with the Clinical Trial Battery in Patients with High Brain Met Velocity Treated with SRS or SRS + HA-WBRT on NRG BN009 |
| Funding Source: | Biomarker, Imaging, & Quality of Life Studies Funding Program NIH/NCI |
| Role: | PI |
| Date: | 2020 - 2022 |
| Title: | A randomized, open-label, multicenter, Phase 2b study to evaluate physical function, including balance and daily activity, in participants with castration-resistant prostate cancer treated with darolutamide or enzalutamide (DaroAct) |
| Funding Source: | Bayer HealthCare Pharmaceuticals Inc |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2020 - 2021 |
| Title: | Mitigating Neurotoxicity and Eradicating Gliomas via UC-MSC-Exos-miR-124 |
| Funding Source: | The Glioblastoma Moon Shot |
| Role: | Project Leader |
| Date: | 2020 - 2023 |
| Title: | Transforming the Standard of Care: A Personalized Approach for Patients with Cancer Metastatic to the Brain |
| Funding Source: | Brockman Foundation Grant |
| Role: | Co-I |
| Date: | 2020 - 2024 |
| Title: | A pilot study to determine the brain and cognitive effects of immune checkpoint inhibitor therapy in patients with melanoma as well as the association of this neurotoxicity with changes in cytokines and the fecal microbiome |
| Funding Source: | Institutional Research Grant Program The University of Texas MD Anderson Cancer Center |
| Role: | PI |
| Date: | 2019 - 2024 |
| Title: | Leveraging Computational Modeling and Graph Theory to Improve Assessment of Cancer-related Cognitive Impairment |
| Funding Source: | NIH/NCI |
| Role: | Multi-Principal Investigator |
| Date: | 2019 - 2025 |
| Title: | SWOG S1827: Real Time Integrated Neurocognitive Function Study Evaluating Neurocognitive Function with the Clinical Trial Battery Biomarker |
| Funding Source: | Imaging & Quality of Life Studies Funding Program NIH/NCI |
| Role: | PI |
| Date: | 2019 - 2022 |
| Title: | Simulation of Surgery-Induced Changes In Brain Connectomics and Prediction of Cognitive Outcomes in Patients with IDH1-Mutant Glioma |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-I |
| Date: | 2019 - 2022 |
| Title: | Protecting the Brain from Chemotherapy |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-I |
| Date: | 2019 - 2022 |
| Title: | Quantitative Imaging and Biofluid Biomarkers Predictive of Neurocognitive Toxicity from Brain Irradiation MTL 1269 |
| Funding Source: | National Aeronautics and Space Administration |
| Role: | Co-PI |
| Date: | 2018 - 2019 |
| Title: | Functional Sequelae of Variable-Radiation Dose Exposure to Network Hubs in Brain Connectomes |
| Funding Source: | CCSG Radiation Oncology and Cancer Imaging Research Program Award The University of Texas MD Anderson Cancer |
| Role: | Co-I |
| Date: | 2018 - 2021 |
| Title: | Development of KOR-8287 for the Prevention of Chemotherapy-induced Peripheral Neuropathy and Chemo Brain |
| Funding Source: | Cancer Prevention Research Institute of Texas-Texas Company Product Development Research Awards, Applicant-Libby Handel |
| Role: | Chief Scientific Advisor |
| Date: | 2018 - 2023 |
| Title: | To wait or not to wait: the timing of radiation therapy for low grade glioma |
| Funding Source: | Patient-Centered Outcomes Research Institute |
| Role: | Co-PI |
| Date: | 2018 - 2023 |
| Title: | A randomized trial of exercise in low grade glioma |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| Date: | 2018 - Present |
| Title: | A randomized trial evaluating stereotactic radiosurgery alone (SRS) to whole brain radiotherapy (WBRT) plus SRS for patients with 5 to 20 brain metastases |
| Funding Source: | Applied Health Research Centre - Canada |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2017 - 2021 |
| Title: | Phase I study of procaspase activating compound-1 (PAC-1) in the treatment of advanced malignancies |
| Funding Source: | Vanquish Therapeutics |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2017 - Present |
| Title: | Phase II Study of BEvacizumab in Combination with ATezolizumab in Patients with Untreated Melanoma Brain Metastases (BEAT-MBM) |
| Funding Source: | Genetech SIV Alliance |
| Role: | Co-I |
| Date: | 2017 - 2021 |
| Title: | A randomized trial of exercise in low grade glioma |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| Date: | 2016 - 2016 |
| Title: | Small-molecule neuroprotectors for treating doxorubicin-induced brain damage |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-PI |
| Date: | 2016 - Present |
| Title: | Phase I/II Trial of Nivolumab with Radiation or Nivolumab and Ipilimumab with Radiation for the Treatment of Intracranial Metastases from Non-Small Cell Lung Cancer |
| Funding Source: | Bristol Meyers Squibb |
| Role: | Co-I |
| Date: | 2016 - 2018 |
| Title: | Cancer therapy-related Arc-development synaptic plasticity impairment |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| Date: | 2016 - 2017 |
| Title: | Will the Omega-3 Fatty Acid DHA Prevent Development of Cognitive-Dysfunction Due to Chemotherapy |
| Funding Source: | Breast Cancer Research Foundation |
| Role: | Consult |
| Date: | 2016 - 2020 |
| Title: | Meditation for the Treatment of Cognitive Dysfunction after Chemotherapy for Women with Breast Cancer: A Randomized Controlled Trial |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2016 - 2021 |
| Title: | Neuroplasticity based behavioral interventions for cancer-related cognitive impairment |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| Date: | 2016 - 2018 |
| Title: | A comprehensive naming approach to language mapping for surgical resection of Glioma |
| Funding Source: | Cancer Survivorship Research Seed Grant The University of Texas MD Anderson Cancer |
| Role: | Mentor |
| Date: | 2016 - Present |
| Title: | METIS: Pivotal, open-label, randomized study of radiosurgery with or without Tumor Treating Fields (TTFields) for 1-10 brain metastases from non-small cell lung cancer (NSCLC) |
| Funding Source: | Novocure |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2016 - 2017 |
| Title: | Proton minibeams: Overcoming proton beams' inability to spare superficial tissues |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2015 - 2016 |
| Title: | Restoration of Brain Function by Mesenchymal Stem Cell Transplantation |
| Funding Source: | Dr. Marnie Rose Foundation |
| Role: | PI |
| Date: | 2015 - 2017 |
| Title: | The ROCKET Study: A Phase 2, Single-arm, Multicenter Trial to Determine the Efficacy and Safety of JCAR015 in Adult Subjects with Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia |
| Funding Source: | Juno Therapeutics |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2015 - Present |
| Title: | A Phase 1b study of JCAR014, autologous T cells engineered to express a CD19-specific chimeric antigen receptor, in combination with durvalumab (MEDI4736) for relapsed/refractory B-cell non-Hodgkin lymphoma |
| Funding Source: | Juno Therapeutics, Clinical Trial Contract |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2015 - Present |
| Title: | A Phase 1, multicenter, open-label study of JCAR017, CD19-targeted chimeric antigen receptor (CAR) T cells, for relapsed and refractory (R/R) B-cell non-Hodgkin Lymphoma (NHL) |
| Funding Source: | Juno Therapeutics |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2015 - 2019 |
| Title: | Preclinical rodent models to determine the safety and efficacy of mesenchymal stem cells for the treatment and prevention of radiation neurotoxicity in glioblastoma |
| Funding Source: | Texas Medical Center Regenerative Medicine Consortium |
| Role: | Co-Program Leader |
| Date: | 2015 - 2016 |
| Title: | Restoration of Brain Function by Mesenchymal Stem Cell Transplantation |
| Funding Source: | MDACC GAP |
| Role: | PI |
| Date: | 2015 - 2020 |
| Title: | Research Training in Academic Medical Oncology |
| Funding Source: | NIH/NCI |
| Role: | Program Faculty Member |
| ID: | T32CA009666 |
| Date: | 2015 - Present |
| Title: | A Randomized, Placebo Controlled Phase 2b/3 Study of ABT-414 with Concurrent Chemoradiation and Adjuvant Temozolomide in Subjects with Newly Diagnosed Glioblastoma (GBM) with Epidermal Growth Factor Receptor (EGFR) Amplification (Intellance 1) |
| Funding Source: | RTOG Foundation |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2014 - 2016 |
| Title: | Inflammation-Induced CNS Glutamate During Breast Cancer Treatment |
| Funding Source: | NIH/NCI |
| Role: | Consult |
| ID: | MH105897 |
| Date: | 2014 - 2015 |
| Title: | Genetic Risk Factors Associated with Radiation Neurotoxicity |
| Funding Source: | Dr. Marnie Rose Foundation |
| Role: | Co-PI |
| Date: | 2014 - 2019 |
| Title: | NCI Community Oncology Research Program (NCORP) Research Bases (UM1) |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| Date: | 2014 - 2020 |
| Title: | A Phase II, Open-Label, Multi-Center Study of ANG1005 in HER+2 Breast Cancer Patients with Progressive/Recurrent Brain Metastases |
| Funding Source: | Angiochem Corporation |
| Role: | Neurocognitive Principal Investigator |
| ID: | Clinical Trial Contract |
| Date: | 2013 - 2017 |
| Title: | Mediation for the Treatment of Cognitive Dysfunction after Chemotherapy |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2012 - 2020 |
| Title: | A Phase II, Open-Label, Multi-center Study of ANG1005 in Patients with Recurrent High-Grade Glioma |
| Funding Source: | Angiochem Corporation |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2012 - 2018 |
| Title: | Multimodal MRI Biomarker of Mild Cognitive Impairment in Breast Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1R01NR014195-01 |
| Date: | 2012 - 2018 |
| Title: | A Double-Blind, Placebo-Controlled, Randomized, Phase IIIb Trial Evaluating the Efficacy and Safety of Standard of Care+/-Continuous Bevacizumab Treatment Following Progression of Disease in Patients with Glioblastoma After First Line Treatment with Radiotherapy, Temozolomide and Bevacizumab |
| Funding Source: | F. Hoffman-La Roche Ltd |
| Role: | Neurocognitive Principal Investigator |
| Date: | 2012 - 2014 |
| Title: | Evaluation of cortical beta-amyloid deposition using florbetapir-positron emission tomography as a biomarker of cognitive impairment and cognitive decline in older women with breast cancer that receive chemotherapy |
| Funding Source: | MD Anderson Cancer Survivorship Research Seed Money |
| Role: | PI |
| Date: | 2012 - 2014 |
| Title: | A Brain Plasticity Based Computerized Intervention to Treat Attention and Memory Problems in Adult Brain Tumor Survivors |
| Funding Source: | UTMDACC Cancer Survivorship Research Seed Money |
| Role: | PI |
| Date: | 2012 - 2015 |
| Title: | A Phase II Trial of HKI-272 (Neratinib) for Patients with Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer and Brain Metastases |
| Funding Source: | Translational Breast Cancer Research Consortium |
| Role: | Neurocognitive PI |
| Date: | 2011 - 2016 |
| Title: | Effects of Meditation on Cognitive Function and Quality of Life in Cancer |
| Funding Source: | UTMDACC Sister Institution Network Fund |
| Role: | Co-PI |
| Date: | 2011 - 2013 |
| Title: | A Phase II, Multi-Center, Open-Label Study Evaluating the Efficacy and Safety of GRN1005 In Non-Small Cell Lung Cancer Patients with Brain Metastases and, A Phase II, Multicenter, Open-Label Study Evaluating GRN1005 Alone or in Combination with Trastuzumab in Breast Cancer Patients with Brain Metastases |
| Funding Source: | Geron |
| Role: | Neurocognitive PI |
| Date: | 2010 - 2014 |
| Title: | A Neurocognitive substudy of BO21990, a randomized, double blind, placebo controlled, multicenter Phase III trial of bevacizumab, temozolomide and radiotherapy, followed by bevacizumab and temozolomide versus placebo, temozolomide and radiotherapy followed by placebo and temozolomide in patients with newly diagnosed glioblastoma |
| Funding Source: | F. Hoffmann-La Roche Ltd |
| Role: | Neurocognitive PI |
| Date: | 2010 - 2015 |
| Title: | Phase 1b/2a Study Combining LY2157299 with Standard Temozolomide-based Radiochemotherapy in Patients with Newly Diagnosed Malignant Glioma |
| Funding Source: | Eli Lilly |
| Role: | Neurocognitive PI |
| Date: | 2009 - 2011 |
| Title: | Phase III double blind placebo controlled trial of conventional concurrent chemoradiation and adjuvant temozolomide plus bevacizumab versus conventional concurrent chemoradiation and adjuvant temozolomide in patients with newly diagnosed glioblastoma |
| Funding Source: | RTOG/Genentech |
| Role: | Neurocognitive PI |
| Date: | 2009 - 2010 |
| Title: | An International, Multi-Center, Randomized, Controlled, Double-Blinded, Phase III Efficacy Study of XL184 versus Lomustine in Subjects with Previously Treated Glioblastoma (Grade 4 Astrocytic Tumors) in First or Second Relapse |
| Funding Source: | Exelixis, Inc |
| Role: | Neurocognitive PI |
| Date: | 2008 - 2013 |
| Title: | SPORE in Brain Cancer Project 4: Genetic modulation of cognitive function and outcomes in glioblastoma patients |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1P50CA127001-02A1 |
| Date: | 2007 - 2010 |
| Title: | Neuropathic Pain Alliance |
| Funding Source: | AstraZeneca |
| Role: | Co-I |
| ID: | CS2007-00021610JW |
| Date: | 2006 - 2010 |
| Title: | Meningioma: Risk Factors and Quality of Life |
| Funding Source: | NCI/NIH |
| Role: | Co-I |
| ID: | R01 CA109473-01 |
| Date: | 2006 - 2011 |
| Title: | Gauging impact of treatment on symptoms, health related quality of life and neurocognitive function in patients with primary brain tumors |
| Funding Source: | ABCC/The Tug McGraw Foundation/Schering-Plough |
| Role: | Co-I |
| Date: | 2006 - 2009 |
| Title: | A Phase II, Multicenter, Randomized, Non-Comparative Clinical Trial to Evaluate the Efficacy and Safety of Bevacizumab Alone or in Combination with Irinotecan for Treatment of Glioblastoma Multiforme in First or Second Relapse |
| Funding Source: | Genentech |
| Role: | Neurocognitive PI |
| ID: | AVF3708g |
| Date: | 2005 - 2007 |
| Title: | The effect of parathyroidectomy on cognition and function in the elderly |
| Funding Source: | Jahnigen Career Development Scholars Award |
| Role: | Co-I |
| Date: | 2005 - 2006 |
| Title: | The effect of parathyroidectomy on functional MRI, cognition, quality of life and sleep in the elderly |
| Funding Source: | Institutional Research Grant The University of Texas MD Anderson Cancer Center |
| Role: | Co-PI |
| Date: | 2005 - 2006 |
| Title: | The effect of parathyroidectomy on functional MRI, cognition, quality of life and sleep in the elderly |
| Funding Source: | Non-Standard-of-Care Clinical Charges Funding, The University of Texas M. D. Anderson Cancer Center |
| Role: | Co-PI |
| Date: | 2001 - 2003 |
| Title: | Psychoneuroendocrinology in Breast Cancer: The effect of tamoxifen on cognitive and emotional functioning in women with breast cancer |
| Funding Source: | The Susan G. Komen Breast Cancer Foundation |
| Role: | PI |
| Title: | A Randomized Controlled Trial of Surgical Resection with GammaTile Therapy and Adjuvant Systemic Therapy compared to Surgical Resection and Adjuvant Systemic Therapy at first recurrence in Glioblastoma |
| Funding Source: | GT Medical Technologies |
| Role: | PI |
Selected Publications
Peer-Reviewed Articles
- Freedland SJ, Aronson W, Asher A, Golant M, Lemke E, Morgans AK, Morris D, Sullivan C, Sutton J, Thomson CA, Twardowski P, Wefel JS, Winters-Stone K, Chakoian M, Wells T, ElSouda D, Turnbull J, Buzaglo J, Mobley C, Ivanova J, Cohen J, Hogue S, El-Chaar N, Touya M. Consensus recommendations for disease- and treatment-related fatigue in patients with advanced prostate cancer: A modified Delphi panel. e-Pub 2025.
- Yeboa DN, Whitfield BT, Lin R, Ejezie CL, Swanson TA, Beckham TH, Wang C, De B, Perni S, Tom MC, Li J, McGovern SL, Harrison R, Majd NK, Puduvalli VK, Aaroe AE, Loghin M, O'Brien BJ, Patel AD, Patel CB, Wefel JS, Taslicay CA, Gule-Monroe M, Paulino AC, McAleer MF, Grosshans DR, Ghia AJ, Jiang W, Chung C, Maor M, Yang CH, Gubbiotti MA, Kamiya-Matsuoka C, Ballester LY, Weathers SP, Huse JT. Prospective phase II clinical trial of molecular glioblastoma (historical grade 2 and 3 IDH wildtype gliomas) preliminary novel exploratory analyses : Treatment intensification, margin reduction and epigenetic stratified outcomes with radiation therapy and chemotherapy. J Neurooncol 176(1):72, 2025. e-Pub 2025. PMID: 41191157.
- Omuro A, DeAngelis LM, Polley MC, Correa D, Wefel JS, Bovi JA, Rosenblum M, Corn BW, Aneja S, Grommes C, Peereboom DM, Lallana EC, Werner-Wasik M, Rogers CL, Iwamoto FM, Yu HM, Donnelly ED, Struve TD, Won M, Mehta MP. Multicenter Randomized Phase II Study of R-MPV-A Chemoimmunotherapy With or Without Low-Dose Whole-Brain Radiotherapy for Newly-Diagnosed Primary CNS Lymphoma. Neuro Oncol, 2025. e-Pub 2025. PMID: 41189315.
- Wefel JS, Schagen SB. Neuropsychological sequelae of cancer and cancer therapy. J Clin Exp Neuropsychol 47(8):701-706, 2025. e-Pub 2025. PMID: 41378822.
- Bander ED, Noll KR, Andrade de Almeida RA, Seaman SC, Banu M, Clark VE, Suki D, Wefel JS, Bradshaw M, Ferguson S, Weinberg JS, Lang FF, Prabhu SS. Relationships Between Surgical Approach, Tumor Classification Scheme, and Early Neurocognitive Outcome After Awake Craniotomy for Resection of Insular Glioma. Oper Neurosurg, 2025. e-Pub 2025. PMID: 40985652.
- Noll KR, Wefel JS. Characterization, etiology, and management of neurocognitive impairment in patients with glioma: an evidentiary update. Curr Opin Neurol, 2025. PMID: 40948080.
- McLeod A, Gabel K, Chakos K, Wefel JS, Tussing-Humphreys L, Oddo VM. The effect of Mediterranean Diet adherence on the relationship between cognitive performance and cancer survivorship. J Cancer Surviv, 2025. e-Pub 2025. PMID: 40789996.
- Lassman AB, Polley MC, Iwamoto FM, Sloan AE, Wang TJC, Aldape KD, Wefel JS, Gondi V, Gutierrez AN, Manasawala MH, Gilbert MR, Sulman EP, Wolchok JD, Green RM, Neil EC, Lukas RV, Goldlust SA, Snuderl M, Galbraith K, Dignam JJ, Won M, Mehta MP. Dual Immune Check Point Blockade in MGMT-Unmethylated Newly Diagnosed Glioblastoma: NRG Oncology BN007, a Randomized Phase II/III Clinical Trial. J Clin Oncol:JCO2500618, 2025. e-Pub 2025. PMID: 40779733.
- Corn BW, Paulus R, Gondi V, Mehta MP, Fogh S, Wefel JS, Videtic GM, Sun A, Yoon H, Heinzerling JH, McGarry RC, Kundapur V, Devisetty K, Wu A, McCarron EC, Pollock J, Kanner AA, Feldman DB, Pugh SL, Kachnic LA, Movsas B. "Hope" Drives Quality of Life in Patients With Brain Metastases, But, the "Hope Center" Remains Elusive: An Analysis of NRG-CC003. Int J Radiat Oncol Biol Phys, 2025. e-Pub 2025. PMID: 40614783.
- Yeboa DN, Li J, Lin R, Prabhu SS, Beckham TH, Woodhouse K, Swanson TA, Weinberg JS, Wang X, Chi X, Ejezie CL, Suki D, Wang C, Ene C, McCutcheon IE, McGovern S, McAleer MF, Tom M, Ghia A, Perni S, Jiang W, De B, Chung C, Kim BYS, O'Brien BJ, Huse JT, Wefel JS, Court L, Tawbi H, Janku F, Guha-Thakurta N, Debnam JM, Johnson J, Taslicay CA, Alvarez-Breckenridge C, Raza SM, Heimberger AB, DeMonte F, North R, Briere TM, de Groot JF, Sawaya R, Grosshans D, Lang FF, Rao G, Ferguson SD. Therapy, Safety, and Logistics of Preoperative vs Postoperative Stereotactic Radiation Therapy: A Preliminary Analysis of a Randomized Clinical Trial. JAMA Oncol, 2025. e-Pub 2025. PMID: 40531511.
- Danielsen, JT, Zachariae, R, Schmidt, H, Kallehauge, JF, Thomadsen, JK, Wefel, JS, Wu, LM, Amidi, A. Cognitive impairment in patients with melanoma before adjuvant immune checkpoint inhibitor therapy and associations with brain gray matter, catechol-O-methyltransferase genotype, and psychological factors. Cancer 131(2), 2025. e-Pub 2025. PMID: 39663713.
- Noll KR, Bander ED, Chen HS, Bradshaw M, Wefel JS, Kumar VA, Prabhu SS, Liu HL. Changes in functional connectivity are associated with functional independence in the early postoperative period following awake surgical resection of language-eloquent glioma. Neurooncol Adv 7(1):vdaf192, 2025. e-Pub 2025. PMID: 41019665.
- Wefel JS, Schagen, S. B.. Neuropsychological sequelae of cancer and cancer therapy. Journal of Clinical and Experimental Neuropsychology 47(8):701-706, 2025. e-Pub 2025.
- Noll KR, Bander ED, Chen HS, Bradshaw M, Wefel JS, Kumar VA, Prabhu SS, Liu H. Changes in functional connectivity are associated with functional independence in the early postoperative period following awake surgical resection of language-eloquent glioma. Neuro-Oncology Advances, 2025. e-Pub 2025.
- Beer TM, George DJ, Shore ND, Winters-Stone K, Wefel JS, Verholen F, Srinivasan S, Ortiz J, Morgans AK. Functional assessment in patients with castration-resistant prostate cancer treated with darolutamide: results from the DaroAcT study. Oncologist 25:oyae287, 2024. PMID: 39450762.
- Janelsins MC, Van Dyk K, Hartman SJ, Koll TT, Cramer CK, Lesser GJ, Barton DL, Mustian KM, Wagner LI, Ganz PA, Cole PD, Bakos A, Root JC, Hardy K, Magnuson A, Ferguson RJ, McDonald BC, Saykin AJ, Gonzalez BD, Wefel JS, Morilak DA, Dahiya S, Heijnen CJ, Conley YP, Morgans AK, Mabbott D, Monje M, Rapp SR, Gondi V, Bender C, Embry L, McCaskill Stevens W, Hopkins JO, St Germain D, Dorsey SG. The National Cancer Institute Clinical Trials Planning Meeting to Address Gaps in Observational and Intervention Trials for Cancer-Related Cognitive Impairment. J Natl Cancer Inst 9:djae209. e-Pub 2024. PMID: 39250738.
- Katlowitz, KA, Beckham, TH, Kudchadker, RJ, Wefel, JS, Elamin, YY, Weinberg, J. A Novel Multimodal Approach to Refractory Brain Metastases. Advances in Radiation Oncology 9(2), 2024. e-Pub 2024. PMID: 38405307.
- Noll KR, Asman P, Tasnim I, Hall M, Connelly K, Swamy C, Ene C, Tummala S, Grasu RM, Liu HL, Kumar VA, Muir M, Prinsloo S, Michener H, Wefel JS, Ince NF, Prabhu SS. Intraoperative language mapping guided by real-time visualization of gamma band modulation electrocorticograms: Case report and proof of concept. Neurooncol Pract 11(1):npad059, 2024. e-Pub 2024. PMID: 38222047.
- Cowan BA, Olivier K, Tombal B, Wefel JS. Treatment-Related Cognitive Impairment in Patients with Prostate Cancer: Patients' Real-World Insights for Optimizing Outcomes. Adv Ther 41(2):476-491, 2024. e-Pub 2024. PMID: 37979089.
- Catalino MP, Noll KR, Wefel JS, Michener H, Prinsloo S, Tummala S, Prabhu S. Decoding the clinical effects of low-grade glioma-induced cortical excitability. J Neurosurg 140(1):18-26, 2024. e-Pub 2024. PMID: 37439490.
- Wefel JS, Deshmukh S, Brown PD, Grosshans DR, Sulman EP, Cerhan JH, Mehta MP, Khuntia D, Shi W, Mishra MV, Suh JH, Laack NN, Chen Y, Curtis AA, Laba JM, Elsayed A, Thakrar A, Pugh SL, Bruner DW. Impact of Apolipoprotein E Genotype on Neurocognitive Function in Patients With Brain Metastases: An Analysis of NRG Oncology's RTOG 0614. Int J Radiat Oncol Biol Phys 13:S0360-3016(23):08238-X, 2023. e-Pub 2023. PMID: 38101486.
- Yaniv, D, Niccolai, LM, Wefel, JS, Sullaway, C, Phan, J, Fuller, C, Haroun, KB, Hanna, EY, Su, SY. Neurocognitive Functioning of Patients with Sinonasal and Nasopharyngeal Cancers Treated with Multimodality Therapy. Journal of Neurological Surgery, Part B: Skull Base 85(6):614-621, 2023. e-Pub 2023. PMID: 39483162.
- Noll KR, Asman P, Tasnim I, Hall M, Connelly K, Swamy C, Ene C, Tummala S, Grasu RM, Liu HL, Kumar VA, Muir M, Prinsloo S, Michener H, Wefel JS, Ince NF, Prabhu SS. Intraoperative language mapping guided by real-time visualization of gamma band modulation electrocorticograms: Case report and proof of concept. Neurooncol Pract 11(1):92-100, 2023. e-Pub 2023. PMID: 38222047.
- Altan M, Wang Y, Song J, Welsh J, Tang C, Guha-Thakurta N, Blumenschein GR, Carter BW, Wefel JS, Ghia AJ, Yeboa DN, McAleer MF, Chung C, Woodhouse KD, McGovern SL, Wang C, Kim BYS, Weinberg JS, Briere TM, Elamin YY, Le X, Cascone T, Negrao MV, Skoulidis F, Ferrarotto R, Heymach JV, Li J. Nivolumab and ipilimumab with concurrent stereotactic radiosurgery for intracranial metastases from non-small cell lung cancer: analysis of the safety cohort for non-randomized, open-label, phase I/II trial. J Immunother Cancer 11(7), 2023. e-Pub 2023. PMID: 37402581.
- Gondi V, Deshmukh S, Brown PD, Wefel JS, Armstrong TS, Tome WA, Gilbert MR, Konski A, Robinson CG, Bovi JA, Benzinger TLS, Roberge D, Kundapur V, Kaufman I, Shah S, Usuki KY, Baschnagel AM, Mehta MP, Kachnic LA. Sustained Preservation of Cognition and Prevention of Patient-Reported Symptoms with Hippocampal Avoidance during Whole-Brain Radiotherapy for Brain Metastases: Final Results of NRG Oncology CC001. Int J Radiat Oncol Biol Phys S0360-3016(23):00438-8, 2023. e-Pub 2023. PMID: 37150264.
- Lassman AB, Pugh SL, Wang TJC, Aldape K, Gan HK, Preusser M, Vogelbaum MA, Sulman EP, Won M, Zhang P, Moazami G, Macsai MS, Gilbert MR, Bain EE, Blot V, Ansell PJ, Samanta S, Kundu MG, Armstrong TS, Wefel JS, Seidel C, de Vos FY, Hsu S, Cardona AF, Lombardi G, Bentsion D, Peterson RA, Gedye C, Bourg V, Wick A, Curran WJ, Mehta MP. Depatuxizumab-mafodotin in EGFR-amplified newly diagnosed glioblastoma: a phase III randomized clinical trial. Neuro Oncol 25(2):339-350, 2023. e-Pub 2023. PMID: 35849035.
- Holdhoff M, Nicholas MK, Peterson RA, Maraka S, Liu LC, Fischer JH, Wefel JS, Fan TM, Vannorsdall T, Russell M, Iacoboni M, Tarasow TM, Hergenrother PJ, Dudek AZ, Danciu OC. Phase I dose-escalation study of procaspase-activating compound-1 in combination with temozolomide in patients with recurrent high-grade astrocytomas. Neurooncol Adv 5(1):vdad087, 2023. e-Pub 2023. PMID: 37554223.
- Gregory TA, Mastall M, Lin H, Hess KR, Yuan Y, Martin-Bejarano Garcia M, Fuller GN, Alfaro KD, Gule-Monroe MK, Huse JT, Khatua S, Rao G, Sandberg DI, Wefel JS, Yeboa DN, Paulino AC, McGovern SL, Zaky W, Mahajan A, Suki D, Weathers SP, Harrison RA, de Groot JF, Puduvalli VK, Penas-Prado M, Majd NK. Characterization of recurrence patterns and outcomes of medulloblastoma in adults: The University of Texas MD Anderson Cancer Center experience. Neurooncol Adv 5(1):vdad032, 2023. e-Pub 2023. PMID: 37114244.
- Katlowitz, K A, Beckham, T H, Kudchadker, R J, Wefel, J, Elamin, Y Y, Weinberg, J S. A Novel Multimodal Approach to Refractory Brain Metastases: A Case Report. Advances in Radiation Oncology:101349, 2023. e-Pub 2023.
- Noll, KR, Wefel, JS. On the classification of impairment in neuropsychological research and practice in the neuro-oncological setting. Neuro-Oncology Practice 9(4):255-256, 2022. e-Pub 2022. PMID: 35859538.
- Pollack A, Karrison TG, Balogh AG, Gomella LG, Low DA, Bruner DW, Wefel JS, Martin AG, Michalski JM, Angyalfi SJ, Lukka H, Faria SL, Rodrigues GB, Beauchemin MC, Lee RJ, Seaward SA, Allen AM, Monitto DC, Seiferheld W, Sartor O, Feng F, Sandler HM. The addition of androgen deprivation therapy and pelvic lymph node treatment to prostate bed salvage radiotherapy (NRG Oncology/RTOG 0534 SPPORT): an international, multicentre, randomised phase 3 trial. Lancet 399(10338):1886-1901, 2022. e-Pub 2022. PMID: 35569466.
- Chung C, Brown PD, Wefel JS. Lessons learned from proton vs photon radiation therapy for glioblastoma signal-finding trial. Neuro Oncol 24(5):851, 2022. e-Pub 2022. PMID: 35460425.
- Muir M, Patel R, Traylor J, de Almeida Bastos DC, Prinsloo S, Liu HL, Noll K, Wefel J, Tummala S, Kumar V, Prabhu S. Validation of Non-invasive Language Mapping Modalities for Eloquent Tumor Resection: A Pilot Study. Front Neurosci 16:833073, 2022. e-Pub 2022. PMID: 35299624.
- Chung C, Brown PD, Wefel JS. Short reply to "Proton therapy for newly diagnosed glioblastoma: More room for investigation" by R. Press et al. Neuro Oncol 23(11):1982, 2021. e-Pub 2021. PMID: 34453547.
- Parsons MW, Peters KB, Floyd SR, Brown P, Wefel JS. Preservation of neurocognitive function in the treatment of brain metastases. Neurooncol Adv 3(5):v96-v107, 2021. e-Pub 2021. PMID: 34859237.
- Wefel JS, Zhou R, Sulman EP, Boehling NS, Armstrong GN, Tsavachidis S, Liang FW, Etzel CJ, Kahalley LS, Small BJ, Scheurer ME, Bondy ML, Liu Y. Genetic modulation of longitudinal change in neurocognitive function among adult glioma patients. J Neurooncol 156(1):185-193, 2021. e-Pub 2021. PMID: 34817796.
- De Witt Hamer PC, Klein M, Hervey-Jumper SL, Wefel JS, Berger MS. In Reply: Functional Outcomes and Health-Related Quality of Life Following Glioma Surgery. Neurosurgery 89(3):E189, 2021. e-Pub 2021. PMID: 34131734.
- Brown PD, Chung C, Liu DD, McAvoy S, Grosshans D, Al Feghali K, Mahajan A, Li J, McGovern SL, McAleer MF, Ghia AJ, Sulman EP, Penas-Prado M, de Groot JF, Heimberger AB, Wang J, Armstrong TS, Gilbert MR, Guha-Thakurta N, Wefel JS. A Prospective Phase II Randomized Trial of Proton Radiotherapy vs. Intensity Modulated Radiotherapy for Patients with Newly Diagnosed Glioblastoma. Neuro Oncol 23(8):1337-1347, 2021. e-Pub 2021. PMID: 33647972.
- Wefel JS, Armstrong TS, Pugh SL, Gilbert MR, Wendland MM, Brachman DG, Roof KS, Brown PD, Crocker IR, Robins HI, Hunter G, Won M, Mehta MP. Neurocognitive, Symptom, and Health- Related Quality of Life Outcomes of a Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma (NRG/RTOG 0825). Neuro Oncol 23(7):1125-1138, 2021. e-Pub 2021. PMID: 33515019.
- Quirarte JA, Kumar VA, Liu HL, Noll KR, Wefel JS, Lang FF. Language supplementary motor area syndrome correlated with dynamic changes in perioperative task-based functional MRI activations: case report. J Neurosurg 134(6):1-5, 2021. e-Pub 2020. PMID: 32502992.
- Jaeckle KA, Ballman KV, van den Bent M, Giannini C, Galanis E, Brown PD, Jenkins RB, Cairncross JG, Wick W, Weller M, Aldape KD, Dixon JG, Anderson SK, Cerhan JH, Wefel JS, Klein M, Grossman SA, Schiff D, Raizer JJ, Dhermain F, Nordstrom DG, Flynn PJ, Vogelbaum MA. CODEL: Phase III study of RT, RT + Temozolomide (TMZ), or TMZ for newly-diagnosed 1p/19q Codeleted Oligodendroglioma. Analysis from the initial study design. Neuro Oncol 23(3):457-467, 2021. e-Pub 2021. PMID: 32678879.
- De Witt Hamer PC, De Witt Hamer PC, Klein M, Hervey-Jumper SL, Wefel JS, Berger MS. Functional Outcomes and Health-Related Quality of Life Following Glioma Surgery. Neurosurgery 88(4):720-732, 2021. e-Pub 2021. PMID: 33517431.
- Noll KR, Chen HS, Wefel JS, Kumar VA, Hou P, Ferguson SD, Rao G, Johnson JM, Schomer DF, Suki D, Prabhu SS, Liu HL. Alterations in functional connectomics associated with neurocognitive changes following glioma resection. Neurosurgery 88(3):544-551, 2021. e-Pub 2021. PMID: 33080024.
- Mrugala MM, Ostrom QT, Pressley SM, Taylor JW, Thomas AA, Wefel JS, Coven SL, Acquaye AA, Haynes C, Agnihotri S, Lim M, Peters KB, Sulman EP, Salcido JT, Butowski NA, Hervey-Jumper S, Mansouri A, Oliver KR, Porter AB, Nassiri F, Schiff D, Dunbar EM, Hegi ME, Armstrong TS, van den Bent MJ, Chang SM, Zadeh G, Chheda MG. The state of neuro-oncology during the COVID-19 pandemic: a worldwide assessment. Neurooncol Adv 3(1):vdab035, 2021. e-Pub 2021. PMID: 34007966.
- Al Feghali KA, Randall JW, Liu DD, Wefel JS, Brown PD, Grosshans DR, McAvoy SA, Farhat MA, Li J, McGovern SL, McAleer MF, Ghia AJ, Paulino AC, Sulman EP, Penas-Prado M, Wang J, de Groot J, Heimberger AB, Armstrong TS, Gilbert MR, Mahajan A, Guha-Thakurta N, Chung C. Phase II trial of proton therapy versus photon IMRT for GBM: secondary analysis comparison of progression-free survival between RANO versus clinical assessment. Neurooncol Adv 3(1):vdab073, 2021. e-Pub 2021. PMID: 34337411.
- Majd NK, Mastall M, Lin H, Dibaj SS, Hess KR, Yuan Y, Garcia MM, Fuller GN, Alfaro KD, Gule-Monroe MK, Huse JT, Khatua S, Rao G, Sandberg DI, Wefel JS, Yeboa DN, Paulino AC, McGovern SL, Zaky W, Mahajan A, Suki D, Weathers SP, Harriso RA, De Groo JF, Puduvalli VK, Penas-Prado M. Clinical characterization of adult medulloblastoma and the effect of first-line therapies on outcome; The MD Anderson Cancer Center experience. Neurooncol Adv 3(1):vdab079, 2021. e-Pub 2021. PMID: 34377987.
- Kumthekar P, Tang SC, Brenner AJ, Kesari S, Piccioni DE, Anders C, Carrillo J, Chalasani P, Kabos P, Puhalla S, Tkaczuk K, Garcia AA, Ahluwalia MS, Wefel JS, Lakhani N, Ibrahim N. ANG1005, a Brain-Penetrating Peptide-Drug Conjugate, Shows Activity in Patients with Breast Cancer with Leptomeningeal Carcinomatosis and Recurrent Brain Metastases. Clin Cancer Res 26(12):2789-2799, 2020. e-Pub 2020. PMID: 31969331.
- Wefel JS. Improving access and standard of care for all. Neurooncol Pract 7(3):261-262, 2020. e-Pub 2020. PMID: 32537174.
- Brown PD, Gondi V, Pugh S, Tome WA, Wefel JS, Armstrong TS, Bovi JA, Robinson C, Konski A, Khuntia D, Grosshans D, Benzinger TLS, Bruner D, Gilbert MR, Roberge D, Kundapur V, Devisetty K, Shah S, Usuki K, Anderson BM, Stea B, Yoon H, Li J, Laack NN, Kruser TJ, Chmura SJ, Shi W, Deshmukh S, Mehta MP, Kachnic LA, Oncology FN. Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001. J Clin Oncol 38(10):1019-1029, 2020. e-Pub 2020. PMID: 32058845.
- Zeng Y, Dong J, Huang M, Zhang JE, Zhang X, Xie M, Wefel JS. Nonpharmacological interventions for cancer-related cognitive impairment in adult cancer patients: A network meta-analysis. Int J Nurs Stud 104:103514, 2020. e-Pub 2020. PMID: 32004776.
- Estevis E, Noll KR, Bradshaw ME, Wefel JS. Driver safety in patients with primary brain tumors. Neurooncol Pract 6(6):490-498, 2019. e-Pub 2019. PMID: 31832220.
- Laack NN, Pugh SL, Brown PD, Fox S, Wefel JS, Meyers C, Choucair A, Khuntia D, Suh JH, Roberge D, Wendland MM, Bruner D. The association of health-related quality of life and cognitive function in patients receiving memantine for the prevention of cognitive dysfunction during whole-brain radiotherapy. Neurooncol Pract 6(4):274-282, 2019. e-Pub 2019. PMID: 31386073.
- Wefel JS. Opportunities to enhance our management, outcomes, and interventions for patients with CNS malignancy. Neurooncol Pract 6(4):247-248, 2019. e-Pub 2019. PMID: 31386055.
- Noll KR, Sullaway CM, Wefel JS. Depressive symptoms and executive function in relation to survival in patients with glioblastoma. J Neurooncol 142(1):183-191, 2019. e-Pub 2019. PMID: 30680509.
- Hall WA, Pugh SL, Wefel JS, Armstrong TS, Gilbert MR, Brachman DG, Werner-Wasik M, Wendland MM, Brown PD, Chao ST, Roof KS, Robins HI, Mehta MP, Curran WJ, Movsas B. Influence of Residual Disease Following Surgical Resection in Newly Diagnosed Glioblastoma on Clinical, Neurocognitive, and Patient Reported Outcomes. Neurosurgery 84(1):66-76, 2019. e-Pub 2019. PMID: 29618054.
- Harrison RA, Kesler SR, Johnson JM, Penas-Prado M, Sullaway CM, Wefel JS. Neurocognitive Dysfunction in Adult Cerebellar Medulloblastoma. Psychooncology 28(1):131-138, 2019. e-Pub 2019. PMID: 30315720.
- Wefel JS. Food for thought: patient outcomes, diagnostic challenges, and therapeutic possibilities. Neurooncol Pract 5(4):203, 2018. e-Pub 2018. PMID: 31385963.
- Noll KR, Bradshaw ME, Weinberg JS, Wefel JS. Neurocognitive functioning is associated with functional independence in newly diagnosed patients with temporal lobe glioma. Neurooncol Pract 5(3):184-193, 2018. e-Pub 2018. PMID: 30094046.
- Hardy SJ, Krull KR, Wefel JS, Janelsins M. Cognitive Changes in Cancer Survivors. Am Soc Clin Oncol Educ Book 38(38):795-806, 2018. e-Pub 2018. PMID: 30231372.
- Noll KR, Bradshaw ME, Rexer J, Wefel JS. Neuropsychological practice in the oncology setting. Arch Clin Neuropsychol 33(3):344-353, 2018. e-Pub 2018. PMID: 29718081.
- Armstrong TS, Vera E, Zhou R, Acquaye AA, Sullaway CM, Berger AM, Breton G, Mahajan A, Wefel JS, Gilbert MR, Bondy M, Scheurer ME. Association of genetic variants with fatigue in patients with malignant glioma. Neurooncol Pract 5(2):122-28, 2018. e-Pub 2018. PMID: 31386001.
- Noll, KR, Bradshaw ME, Weinberg, Wefel JS. Neurocognitive functioning is associated with functional independence in patients with temporal lobe glioma. Neuro-Oncology Practice 5(3):184-193, 2018. e-Pub 2018.
- Wefel JS. Patient-centered care in Neuro-Oncology. Neurooncol Pract 5(1):1, 2018. e-Pub 2018. PMID: 31385979.
- Brown PD, Ahluwalia MS, Khan OH, Asher AL, Wefel JS, Gondi V. Whole-Brain Radiotherapy for Brain Metastases: Evolution or Revolution?. J Clin Oncol 36(5):483-491, 2018. e-Pub 2018. PMID: 29272161.
- Alexander BM, Brown PD, Ahluwalia MS, Aoyama H, Baumert BG, Chang SM, Gaspar LE, Kalkanis SN, Macdonald DR, Mehta MP, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wefel JS, Lee EQ, Wen PY. Response Assessment in Neuro-Oncology (RANO): Clinical trial design for local therapies for brain metastases. Lancet Oncology, Lancet Oncol 19(1):e33-e42, 2018. e-Pub 2018.
- Moruno-Manchon JF, Uzor NE, Kesler SR, Wefel JS, Townley DM, Nagaraja AS, Pradeep S, Mangala LS, Sood AK, Tsvetkov AS. Peroxisomes contribute to oxidative stress in neurons during doxorubicin-based chemotherapy. Mol Cell Neurosci 86:65-71, 2018. e-Pub 2018. PMID: 29180229.
- Wefel JS, Parsons MW, Gondi V, Brown PD. Neurocognitive aspects of brain metastasis. Handb Clin Neurol 149:155-165, 2018. e-Pub 2018. PMID: 29307352.
- Schagen SB, Wefel JS. Post-traumatic Stress as the Primary Cause for Cognitive Decline-Not the Whole Story, and Perhaps No Story at All. J Natl Cancer Inst 109(10), 2017. e-Pub 2017. PMID: 28521366.
- Hansen CC, Smith JB, Mohamed ASR, Mulcahy CF, Wefel JS, Hutcheson KA, Chrane K, Phan J, Frank SJ, Garden AS, Smith BD, Eichelberger H, Anderson C, McCoy C, Horiates M, Patrick C, Floris S, French C, Beadle BM, Morrison WH, Su SY, Lewis CM, Kupferman ME, Johnson JM, Skinner HD, Lai SY, Hanna EY, Rosenthal DI, Fuller CD, Gunn GB, Head MD, Working Group NCS. Cognitive function and patient-reported memory problems after radiotherapy for cancers at the skull base: A cross-sectional survivorship study using the Telephone Interview for Cognitive Status and the MD Anderson Symptom Inventory-Head and Neck Module. Head Neck 39(10):2048-2056, 2017. e-Pub 2017. PMID: 28763137.
- El Salek KE, Hassan IS, Kotrotsou A, Abrol S, Faro SH, Mohamed FB, Zinn PO, Wei W, Li N, Kumar AJ, Weinberg JS, Wefel JS, Kesler SR, Liu HA, Hou P, Stafford RJ, Prabhu S, Sawaya R, Colen RR. Silent Sentence Completion Shows Superiority Localizing Wernicke's Area and Activation Patterns of Distinct Language Paradigms Correlate with Genomics: Prospective Study. Sci Rep 7(1):12054, 2017. e-Pub 2017. PMID: 28935966.
- Noll KR, Bradshaw ME, Weinberg JS, Wefel JS. Relationships between neurocognitive functioning, mood, and quality of life in patients with temporal lobe glioma. Psychooncology 26(5):617-624, 2017. e-Pub 2017. PMID: 26677053.
- Wefel JS, Noll KR, Rao G, Cahill DP. Reply to Freyschlag et al. Neuro Oncol 19(4):598-599, 2017. e-Pub 2017. PMID: 28339696.
- Nayak L, de Groot J, Wefel JS, Cloughesy TF, Lieberman F, Chang SM, Omuro A, Drappatz J, Batchelor TT, DeAngelis LM, Gilbert MR, Aldape KD, Yung AW, Fisher J, Ye X, Chen A, Grossman S, Prados M, Wen PY. Phase I trial of aflibercept (VEGF trap) with radiation therapy and concomitant and adjuvant temozolomide in patients with high-grade gliomas. J Neurooncol 132(1):181-188, 2017. e-Pub 2017. PMID: 28116649.
- Kesler SR, Noll K, Cahill DP, Rao G, Wefel JS. The effect of IDH1 mutation on the structural connectome in malignant astrocytoma. J Neurooncol 131(3):565-574, 2017. e-Pub 2017. PMID: 27848136.
- Wefel. Choosing clinical trial endpoints, aggregating data, and making clinical decisions. Neuro-Oncology Practice 4(4):199-200, 2017. e-Pub 2017.
- Wefel JS, Noll KR, Rao G, Cahill DP. Neurocognitive function varies by IDH1 genetic mutation status in patients with malignant glioma prior to surgical resection. Neuro Oncol 18(12):1656-1663, 2016. e-Pub 2016. PMID: 27576872.
- Moruno-Manchon JF, Uzor NE, Kesler SR, Wefel JS, Townley DM, Nagaraja AS, Pradeep S, Mangala LS, Sood AK, Tsvetkov AS. TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin. Aging (Albany NY) 8(12):3507-19, 2016. e-Pub 2016. PMID: 27992857.
- Noll KR, Ziu M, Weinberg JS, Wefel JS. Neurocognitive functioning in patients with glioma of the left and right temporal lobes. J Neurooncol 128(2):323-31, 2016. e-Pub 2016. PMID: 27022915.
- Manchon JF, Dabaghian Y, Uzor NE, Kesler SR, Wefel JS, Tsvetkov AS. Levetiracetam mitigates doxorubicin-induced DNA and synaptic damage in neurons. Sci Rep 6:25705, 2016. e-Pub 2016. PMID: 27168474.
- Freedman RA, Gelman RS, Wefel JS, Melisko ME, Hess KR, Connolly RM, Van Poznak CH, Niravath PA, Puhalla SL, Ibrahim N, Blackwell KL, Moy B, Herold C, Liu MC, Lowe A, Agar NY, Ryabin N, Farooq S, Lawler E, Rimawi MF, Krop IE, Wolff AC, Winer EP, Lin NU. Translational Breast Cancer Research Consortium (TBCRC) 022: A Phase II Trial of Neratinib for Patients With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases. J Clin Oncol 34(9):945-52, 2016. e-Pub 2016. PMID: 26834058.
- Wefel JS, Noll KR, Scheurer ME. Neurocognitive functioning and genetic variation in patients with primary brain tumours. Lancet Oncol 17(3):e97-108, 2016. e-Pub 2016. PMID: 26972863.
- Blakeley JO, Coons SJ, Corboy JR, Kline Leidy N, Mendoza TR, Wefel JS. Clinical outcome assessment in malignant glioma trials: measuring signs, symptoms, and functional limitations. Neuro Oncol 18 Suppl 2:ii13-ii20, 2016. e-Pub 2016. PMID: 26989128.
- Noll KR, Weinberg JS, Ziu M, Wefel JS. Verbal Learning Processes in Patients with Glioma of the Left and Right Temporal Lobes. Arch Clin Neuropsychol 31(1):37-46, 2016. e-Pub 2016. PMID: 26537777.
- Noll KR, Weinberg JS, Ziu M, Benveniste RJ, Suki D, Wefel JS. Neurocognitive Changes Associated With Surgical Resection of Left and Right Temporal Lobe Glioma. Neurosurgery 77(5):777-85, 2015. e-Pub 2015. PMID: 26317672.
- Noll KR, Wefel JS. Response to "From histology to neurocognition: the influence of tumor grade in glioma of the left temporal lobe on neurocognitive function". Neuro Oncol 17(10):1421-2, 2015. e-Pub 2015. PMID: 26395063.
- Liu Y, Zhou R, Sulman EP, Scheurer ME, Boehling N, Armstrong GN, Tsavachidis S, Liang FW, Etzel CJ, Conrad CA, Gilbert MR, Armstrong TS, Bondy ML, Wefel JS. Genetic Modulation of Neurocognitive Function in Glioma Patients. Clin Cancer Res 21(14):3340-6, 2015. e-Pub 2015. PMID: 25904748.
- Noll KR, Sullaway C, Ziu M, Weinberg JS, Wefel JS. Relationships between tumor grade and neurocognitive functioning in patients with glioma of the left temporal lobe prior to surgical resection. Neuro Oncol 17(4):580-7, 2015. e-Pub 2015. PMID: 25227126.
- Wefel JS, Kesler SR, Noll KR, Schagen SB. Clinical characteristics, pathophysiology, and management of noncentral nervous system cancer-related cognitive impairment in adults. CA Cancer J Clin 65(2):123-38, 2015. e-Pub 2015. PMID: 25483452.
- Wefel JS. Neuro-Oncology Practice: Time Flies When You Are Having Fun!. Neurooncol Pract 1(4):143-144, 2014. e-Pub 2014. PMID: 26034625.
- Wefel JS, Vidrine DJ, Marani SK, Swartz RJ, Veramonti TL, Meyers CA, Hoekstra HJ, Hoekstra-Weebers JE, Gritz ER. A prospective study of cognitive function in men with non-seminomatous germ cell tumors. Psychooncology 23(6):626-33, 2014. e-Pub 2014. PMID: 24339329.
- Schagen SB, Klein M, Reijneveld JC, Brain E, Deprez S, Joly F, Scherwath A, Schrauwen W, Wefel JS. Monitoring and optimising cognitive function in cancer patients: Present knowledge and future directions. EJC Suppl 12(1):29-40, 2014. e-Pub 2014. PMID: 26217164.
- Wefel JS, Kornet RL, Schagen SB. Systemically Treated Breast Cancer Patients and Controls: an Evaluation of the Presence of Noncredible Performance. J Int Neuropsychol Soc 20(4):1-13, 2014. e-Pub 2014. PMID: 24607070.
- Gilbert MR, Dignam JJ, Armstrong TS, Wefel JS, Blumenthal DT, Vogelbaum MA, Colman H, Chakravarti A, Pugh S, Won M, Jeraj R, Brown PD, Jaeckle KA, Schiff D, Stieber VW, Brachman DG, Werner-Wasik M, Tremont-Lukats IW, Sulman EP, Aldape KD, Curran WJ, Mehta MP. A randomized trial of bevacizumab for newly diagnosed glioblastoma. N Engl J Med 370(8):699-708, 2014. e-Pub 2014. PMID: 24552317.
- Jones D, Vichaya EG, Wang XS, Sailors MH, Cleeland CS, Wefel JS. Acute Cognitive Impairment in Patients with Multiple Myeloma Undergoing Autologous Hematopoietic Stem Cell Transplant. Cancer 119(23):4188-95, 2013. e-Pub 2013. PMID: 24105672.
- Kesler SR, Watson C, Koovakkattu D, Lee C, O'Hara R, Mahaffey ML, Wefel JS. Elevated prefrontal myo-inositol and choline following breast cancer chemotherapy. Brain Imaging Behav 7(4):501-10, 2013. e-Pub 2013. PMID: 23536015.
- Gilbert MR, Wang M, Aldape KD, Stupp R, Hegi ME, Jaeckle KA, Armstrong TS, Wefel JS, Won M, Blumenthal DT, Mahajan A, Schultz CJ, Erridge S, Baumert B, Hopkins KI, Tzuk-Shina T, Brown PD, Chakravarti A, Curran WJ, Mehta MP. Dose Dense Temozolomide for Newly Diagnosed Glioblastoma: A Randomized Phase III Clinical Trial. J Clin Oncol 31(32):4085-91, 2013. e-Pub 2013. PMID: 24101040.
- Armstrong TS, Wefel JS, Wang M, Gilbert MR, Won M, Bottomley A, Mendoza TR, Coens C, Werner-Wasik M, Brachman DG, Choucair AK, Mehta M. Net Clinical Benefit Analysis of Radiation Therapy Oncology Group 0525: A Phase III Trial Comparing Conventional Adjuvant Temozolomide With Dose-Intensive Temozolomide in Patients With Newly Diagnosed Glioblastoma. J Clin Oncol 31(32):4076-84, 2013. e-Pub 2013. PMID: 24101048.
- Brown PD, Pugh S, Laack NN, Wefel JS, Khuntia D, Meyers C, Choucair A, Fox S, Suh JH, Roberge D, Kavadi V, Bentzen SM, Mehta MP, Watkins-Bruner D, Oncology Group RT. Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial. Neuro Oncol 15(10):1429-37, 2013. e-Pub 2013. PMID: 23956241.
- Lin NU, Lee EQ, Aoyama H, Barani IJ, Baumert BG, Brown PD, Camidge DR, Chang SM, Dancey J, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Lamborn KR, Linskey ME, Macdonald DR, Margolin K, Mehta MP, Schiff D, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wefel JS, Wen PY, Neuro-Oncology group RAI. Challenges relating to solid tumour brain metastases in clinical trials, part 1: patient population, response, and progression. A report from the RANO group. Lancet Oncol 14(10):e396-406, 2013. e-Pub 2013. PMID: 23993384.
- Kesler SR, Wefel JS, Hosseini SM, Cheung M, Watson CL, Hoeft F. Default mode network connectivity distinguishes chemotherapy-treated breast cancer survivors from controls. Proc Natl Acad Sci U S A 110(28):11600-5, 2013. e-Pub 2013. PMID: 23798392.
- Taychakhoonavudh S, Franzini L, Lal L, Chang E, Meyers CA, Wefel JS, Swint JM. Comparison of patient reported outcomes (pros) and clinician reported outcomes (cros) in patients with metastatic brain disease. Value Health 16(3):A145-6, 2013. e-Pub 2013. PMID: 23693422.
- Johnson DR, Wefel JS. Relationship between cognitive function and prognosis in glioblastoma. CNS Oncol 2(2):195-201, 2013. e-Pub 2013. PMID: 25057978.
- Welsh JW, Komaki R, Amini A, Munsell MF, Unger W, Allen PK, Chang JY, Wefel JS, McGovern SL, Garland LL, Chen SS, Holt J, Liao Z, Brown P, Sulman E, Heymach JV, Kim ES, Stea B. Phase II Trial of Erlotinib Plus Concurrent Whole-Brain Radiation Therapy for Patients With Brain Metastases From Non-Small-Cell Lung Cancer. J Clin Oncol 31(7):895-902, 2013. e-Pub 2013. PMID: 23341526.
- Armstrong TS, Wefel JS, Gning I, Acquaye A, Vera-Bolanos E, Gilbert MR, Cleeland CS, Mendoza T. Congruence of Primary BrainTumor Patient and Caregiver Symptom Report. Cancer 118(20):5026-37, 2012. e-Pub 2012. PMID: 22415423.
- Wefel JS, Schagen SB. Chemotherapy-Related Cognitive Dysfunction. Curr Neurol Neurosci Rep 12(3):267-75, 2012. e-Pub 2012. PMID: 22453825.
- Johnson DR, Sawyer AM, Meyers CA, O'Neill BP, Wefel JS. Early Measures of Cognitive Function Predict Survival in Patients with Newly Diagnosed Glioblastoma. Neuro Oncol 14(6):808-16, 2012. e-Pub 2012. PMID: 22508762.
- Schapiro R, Ferson D, Prabhu SS, Tummula S, Wefel J, Rao G. A Technique for Mapping Cortical Areas Associated with Speech Arrest. Stereotact Funct Neurosurg 90(2):118-123. e-Pub 2012. PMID: 22398728.
- Gehring K, Patwardhan SY, Collins R, Groves MD, Etzel CJ, Meyers CA, Wefel JS. A randomized trial on the efficacy of methylphenidate and modafinil for improving cognitive functioning and symptoms in patients with a primary brain tumor. J Neurooncol 107(1):165-74, 2012. e-Pub 2012. PMID: 21964738.
- Wu AS, Witgert ME, Lang FF, Xiao L, Bekele BN, Meyers CA, Ferson D, Wefel JS. Neurocognitive Function Before and After Surgery for Insular Gliomas. J Neurosurg 115(6):1115-25, 2011. e-Pub 2011. PMID: 21905800.
- Wefel JS, Vardy J, Ahles T, Schagen SB. International Cognition and Cancer Task Force recommendations to harmonise studies of cognitive function in patients with cancer. Lancet Oncol 12(7):703-8, 2011. e-Pub 2011. PMID: 21354373.
- van den Bent MJ, Wefel JS, Schiff D, Taphoorn MJ, Jaeckle K, Junck L, Armstrong T, Choucair A, Waldman AD, Gorlia T, Chamberlain M, Baumert BG, Vogelbaum MA, Macdonald DR, Reardon DA, Wen PY, Chang SM, Jacobs AH. Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas. Lancet Oncol 12(6):583-93, 2011. e-Pub 2011. PMID: 21474379.
- Wefel JS, Cloughesy T, Zazzali JL, Zheng M, Prados M, Wen PY, Mikkelsen T, Schiff D, Abrey LE, Yung WK, Paleologos N, Nicholas MK, Jensen R, Vredenburgh J, Das A, Friedman HS. Neurocognitive function in patients with recurrent glioblastoma treated with bevacizumab. Neuro Oncol 13(6):660-8, 2011. e-Pub 2011. PMID: 21558074.
- Levin VA, Bidaut L, Hou P, Kumar AJ, Wefel JS, Bekele BN, Prabhu S, Loghin M, Gilbert MR, Jackson EF. Randomized Double-Blind Placebo-Controlled Trial of Bevacizumab Therapy for Radiation Necrosis of the Central Nervous System. Int J Radiat Oncol Biol Phys 79(5):1487-95, 2011. e-Pub 2011. PMID: 20399573.
- Reardon DA, Galanis E, DeGroot JF, Cloughesy TF, Wefel JS, Lamborn KR, Lassman AB, Gilbert MR, Sampson JH, Wick W, Chamberlain MC, Macdonald DR, Mehta MP, Vogelbaum MA, Chang SM, Van den Bent MJ, Wen PY. Clinical trial end points for high-grade glioma: the evolving landscape. Neuro Oncol 13(3):353-61, 2011. e-Pub 2011. PMID: 21310734.
- Wefel JS, Vidrine DJ, Veramonti TL, Meyers CA, Marani SK, Hoekstra HJ, Hoekstra-Weebers JE, Shahani L, Gritz ER. Cognitive Impairment in Men with Testicular Cancer Prior to Adjuvant Therapy. Cancer 117(1):190-6, 2011. e-Pub 2011. PMID: 20737560.
- Wefel JS, Saleeba AK, Buzdar AU, Meyers CA. Acute and late onset cognitive dysfunction associated with chemotherapy in women with breast cancer. Cancer 116(14):3348-56, 2010. e-Pub 2010. PMID: 20564075.
- Perrier ND, Balachandran D, Wefel JS, Jimenez C, Busaidy N, Morris GS, Dong W, Jackson E, Weaver S, Gantela S, Evans DB, Grubbs EG, Lee JE. Prospective, randomized, controlled trial of parathyroidectomy versus observation in patients with "asymptomatic" primary hyperparathyroidism. Surgery 146(6):1116-22, 2009. e-Pub 2009. PMID: 19879613.
- Chang EL, Wefel JS, Hess KR, Allen PK, Lang FF, Kornguth DG, Arbuckle RB, Swint JM, Shiu AS, Maor MH, Meyers CA. Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial. Lancet Oncol 10(11):1037-44, 2009. e-Pub 2009. PMID: 19801201.
- Benge JF, Perrier ND, Massman PJ, Meyers CA, Kayl AE, Wefel JS. Cognitive and Affective Sequelae of Primary Hyperparathyroidism and Early Response to Parathyroidectomy. J Int Neuropsychol Soc 15(6):1002-11, 2009. e-Pub 2009. PMID: 19807940.
- Friedman MA, Fernandez M, Wefel JS, Myszka KA, Champlin RE, Meyers CA. Course of Cognitive Decline in Hematopoietic Stem Cell Transplantation: A Within-subjects Design. Arch Clin Neuropsychol 24(7):689-98, 2009. e-Pub 2009. PMID: 19767298.
- Groves MD, Glantz MJ, Chamberlain MC, Baumgartner KE, Conrad CA, Hsu S, Wefel JS, Gilbert MR, Ictech S, Hunter KU, Forman AD, Puduvalli VK, Colman H, Hess KR, Yung WK. A multicenter Phase II trial of intrathecal topotecan in patients with meningeal malignancies. Neuro Oncol 10(2):208-15, 2008. e-Pub 2008. PMID: 18316473.
- Vardy J, Wefel JS, Ahles T, Tannock IF, Schagen SB. Cancer and cancer-therapy related cognitive dysfunction: an international perspective from the Venice cognitive workshop. Ann Oncol 19(4):623-629, 2008. e-Pub 2008. PMID: 17974553.
- Mittendorf EA, Wefel JS, Meyers CA, Shapiro SE, Doherty DB, Lee JE, Evans DB, Perrier ND. Improvement of sleep disturbance and neurocognitive function after parathyroidectomy in patients with primary hyperparathyroidism. Endocr Pract 13(4):338-44, 2007. e-Pub 2007. PMID: 17669708.
- Chang EL, Wefel JS, Maor MH, Hassenbusch SJ, rd, Mahajan A, Lang FF, Woo SY, Mathews LA, Allen PK, Shiu AS, Meyers CA. A pilot study of neurocognitive function in patients with one to three new brain metastases initially treated with stereotactic radiosurgery alone. Neurosurgery 60(2):277-83; discussion 283-4, 2007. e-Pub 2007. PMID: 17290178.
- Wefel JS, Lenzi R, Theriault R, Buzdar AU, Cruickshank S, Meyers CA. 'Chemobrain' in breast carcinoma?: a prologue. Cancer 101(3):466-75, 2004. e-Pub 2004. PMID: 15274059.
- Wefel JS, Lenzi R, Theriault RL, Davis RN, Meyers CA. The cognitive sequelae of standard-dose adjuvant chemotherapy in women with breast carcinoma: results of a prospective, randomized, longitudinal trial. Cancer 100(11):2292-9, 2004. e-Pub 2004. PMID: 15160331.
- Atchison TA, Sanders A, Struchen M, Roebuck T, Wefel JS, High W, Contant C. Relationship between neuropsychological test performance and productivity at 1-year following traumatic brain injury. Clin Neuropsychol 18(2):249-265, 2004. e-Pub 2004. PMID: 15587672.
- Wefel JS, Hoyt BD, Massman PJ. Cognitive Function in Depressed versus Non-Depressed AD Patients. The Clinical Neuropsychologist(13):249-257, 1999. e-Pub 1999.
- Suhr J, Tranel D, Wefel J, Barrash J. Memory Performance after Head Injury: Contributions of Malingering, Litigation Status, Psychological Factors, and Medication Use. Journal of Clinical and Experimental Neuropsychology(19):500-514, 1997. e-Pub 1997.
Invited Articles
- Lassman, A. B., Polley, M. C., Iwamoto, F. M., Sloan, A. E., Wang, T. J. C., Aldape, K. D., Wefel JS, Gondi, V., Gutierrez, A. N., Manasawala, M. H., Gilbert, M. R., Sulman, E. P., Wolchok, J. D., Green, R. M., Neil, E. C., Lukas, R. V., Goldlust, S. A., Snuderl, M., Galbraith, K., Dignam, J. J., Mehta, M. P.. Dual Immune Check Point Blockade in MGMT-Unmethylated Newly Diagnosed Glioblastoma: NRG Oncology BN007, a Randomized Phase II/III Clinical Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, JCO2500618, 2025. e-Pub 2025.
- Gondi, V., Pugh, S. L., Mehta, M. P., Wefel JS, Tomé, W. A., Sun, A. Y., Grecula, J., Redmond, K. J., Fogh, S., Gaspar, L., Konski, A., Bovi, J., Robinson, C. G., Corn, B., Videtic, G. M., Lok, B. H., Yoon, H. A., Heinzerling, J. H., DeNittis, A. S., McGarry, R. C.. Hippocampal Avoidance During Prophylactic Cranial Irradiation for Patients With Small Cell Lung Cancer: Randomized Phase II/III Trial NRG-CC003. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, JCO2500221, 2025. e-Pub 2025. PMID: 40789106.
- Sheppard DP, Noll KR, Wefel JS, Bradshaw ME. Neuropsychological Evaluation for Oncology. Neurol Clin 42(4):875-887, 2024. e-Pub 2024. PMID: 39343481.
- Wefel JS, Woods SP. Measuring everyday functioning in patients with brain tumor: The long rows yet to hoe. Neurooncol Pract 9(4):253-254, 2022. e-Pub 2022. PMID: 35859540.
- Parsons MW, Peters KB, Floyd SR, Brown P, Wefel JS. Preservation of neurocognitive function in the treatment of brain metastases. Neurooncol Adv 3(5):v96-v107, 2021. e-Pub 2021. PMID: 34859237.
- Noll KR, Walbert T, Wefel JS. Impaired neurocognitive function in glioma patients: from pathophysiology to novel intervention strategies. Curr Opin Neurol 33(6):716-722, 2020. e-Pub 2020. PMID: 33009006.
- Noll KR, Bradshaw ME, Parsons MW, Dawson EL, Rexer J, Wefel JS. Monitoring of Neurocognitive Function in the Care of Patients with Brain Tumors. Curr Treat Options Neurol 21(7):33, 2019. e-Pub 2019. PMID: 31250277.
- Wefel JS, Bradshaw ME. A Closer Look at the Effects of Cancer and Cancer Treatment on Cognitive Function. Coping with Cancer Magazine, 2019. e-Pub 2019.
- Harrison RA, Wefel JS. Neurocognitive Function in Adult Cancer Patients. Neurol Clin 36(3):653-674, 2018. e-Pub 2018. PMID: 30072075.
- Wefel JS, Bradshaw ME. Coping with the Cognitive Side Effects of Cancer. Coping Magazine, 2015. e-Pub 2015.
- Day J, Yust-Katz S, Cachia D, Rooney A, Katz LH, Wefel J, Tremont I, Armstrong T. To assess the effective management of pharmacological and non-pharmacological interventions for reducing fatigue in patients with a primary brain tumour (PBT). Cochrane Gynaecological Cancer Group DOI:10.1002/14651858.CD011376, 2014. e-Pub 2014.
- Dietrich J, Monje M, Wefel J, Meyers C. Clinical patterns and biological correlates of cognitive dysfunction associated with cancer therapy. Oncologist 13(12):1285-1295, 2008. e-Pub 2008. PMID: 19019972.
- Wefel JS, Witgert ME, Meyers CA. Neuropsychological sequelae of non-central nervous system cancer and cancer therapy. Neuropsychol Rev 18(2):121-31, 2008. e-Pub 2008. PMID: 18415683.
- Kayl AE, Wefel JS, Meyers CA. Chemotherapy and cognition: effects, potential mechanisms, and management. Am J Ther 13(4):362-9, 2006. e-Pub 2006. PMID: 16858172.
- Wefel JS, Kayl AE, Meyers CA. Neuropsychological dysfunction associated with cancer and cancer therapies: a conceptual review of an emerging target. Br J Cancer 90(9):1691-6, 2004. e-Pub 2004. PMID: 15150608.
Review Articles
- Mondia MWL, Avila EK, Wefel JS, Hehn RF, Bowers AR, Cox BS, Cox DJ, Schiff D. Brain tumors and fitness to drive: A review and multi-disciplinary approach. Neurooncol Pract 12(2):183-196, 2025. e-Pub 2025. PMID: 40110067.
- Rock V, Ahluwalia MS, Anthony M, Arons D, Arzbaecher J, Dunbar E, Fraher C, Freund M, Gondi V, Khanuja S, Leach D, Loughan AR, Musella A, Oliver K, Paabo K, Puduvalli VK, Shaffer GD, Thomas AA, Wallgren K, Wefel JS, Yu JS, Zada G, Willmarth N, DeVitto R. Guiding principles for adult CNS tumor treatment programs. Neurooncol Adv 7(1):vdaf169, 2025. e-Pub 2025. PMID: 40980442.
- Sheppard, D, Noll, KR, Wefel, JS, Bradshaw, ME. Neuropsychological Evaluation for Oncology. Neurologic Clinics 42(4):875-887, 2024. e-Pub 2024. PMID: 39343481.
- Wilcox, JA, Chukwueke, U, Ahn, MJ, Aizer, A, Bale, T, Brandsma, D, Brastianos, PK, Chang, SM, Daras, M, Forsyth, P, Garzia, L, Glantz, MJ, Oliva, IC, Kumthekar, P, Le Rhun, E, Nagpal, S, O'Brien, BJ, Pentsova, E, Lee, EQ, Remsik, J, Ruda, R, Smalley, I, Taylor, MD, Weller, M, Wefel, JS, Yang, JT, Young, RJ, Wen, PY, Boire, A. Leptomeningeal metastases from solid tumors. Neuro-oncology 26(10):1781-1804, 2024. e-Pub 2024. PMID: 38902944.
- Noll KR, Bradshaw M, Sheppard D, Wefel JS. Perioperative Neurocognitive Function in Glioma Surgery. Curr Oncol Rep 26(5):466-476, 2024. e-Pub 2024. PMID: 38573439.
- Cowan BA, Olivier K, Tombal B, Wefel JS. Correction to: Treatment-Related Cognitive Impairment in Patients with Prostate Cancer: Patients' Real-World Insights for Optimizing Outcomes. Adv Ther 41(4):1770-1773, 2024. e-Pub 2024. PMID: 38378976.
- Guran E, Hu J, Wefel JS, Chung C, Cata JP. Perioperative considerations in patients with chemotherapy-induced cognitive impairment: a narrative review. Br J Anaesth 129(6):909-922, 2022. e-Pub 2022. PMID: 36270848.
- Beer TM, Shore N, Morgans A, Winters-Stone K, Wefel JS, George DJ. Functional impact of androgen-targeted therapy on patients with castration-resistant prostate cancer. BJUI Compass 3(6):424-433, 2022. e-Pub 2022. PMID: 36267196.
- Day J, Yust-Katz S, Cachia D, Wefel J, Tremont Lukats IW, Bulbeck H, Rooney AG. Interventions for the management of fatigue in adults with a primary brain tumour. Cochrane Database Syst Rev 9(9):CD011376, 2022. e-Pub 2022. PMID: 36094728.
- Wefel JS, Ryan CJ, Van J, Jackson JC, Morgans AK. Assessment and Management of Cognitive Function in Patients with Prostate Cancer Treated with Second-Generation Androgen Receptor Pathway Inhibitors. CNS Drugs 36(5):419-449, 2022. e-Pub 2022. PMID: 35522374.
- Schagen SB, Tsvetkov AS, Compter A, Wefel JS. Cognitive adverse effects of chemotherapy and immunotherapy: are interventions within reach?. Nat Rev Neurol 18(3):173-185, 2022. e-Pub 2022. PMID: 35140379.
- Noll K, King AL, Dirven L, Armstrong TS, Taphoorn MJB, Wefel JS. Neurocognition and Health-Related Quality of Life Among Patients with Brain Tumors. Hematol Oncol Clin North Am 36(1):269-282, 2022. e-Pub 2022. PMID: 34711455.
- Lehrer EJ, Jones BM, Dickstein DR, Green S, Germano IM, Palmer JD, Laack N, Brown PD, Gondi V, Wefel JS, Sheehan JP, Trifiletti DM. The Cognitive Effects of Radiotherapy for Brain Metastases. Front Oncol 12:893264, 2022. e-Pub 2022. PMID: 35847842.
- Ryan C, Wefel JS, Morgans AK. A review of prostate cancer treatment impact on the CNS and cognitive function. Prostate Cancer Prostatic Dis 23(2):207-219, 2020. e-Pub 2020. PMID: 31844181.
- van Lonkhuizen PJC, Klaver KM, Wefel JS, Sitskoorn MM, Schagen SB, Gehring K. Interventions for cognitive problems in adults with brain cancer: A narrative review. Eur J Cancer Care (Engl) 28(3):e13088, 2019. e-Pub 2019. PMID: 31090162.
- Zeng Y, Zhang JE, Cheng ASK, Cheng H, Wefel JS. Meta-Analysis of the Efficacy of Virtual Reality-Based Interventions in Cancer-Related Symptom Management. Integr Cancer Ther 18:1534735419871108, 2019. e-Pub 2019. PMID: 31441352.
- Alexander BM, Brown PD, Ahluwalia MS, Aoyama H, Baumert BG, Chang SM, Gaspar LE, Kalkanis SN, Macdonald DR, Mehta MP, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wefel JS, Lee EQ, Wen PY, Neuro-Oncology group RAI. Clinical trial design for local therapies for brain metastases: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group. Lancet Oncol 19(1):e33-e42, 2018. e-Pub 2018. PMID: 29304360.
- Camidge DR, Lee EQ, Lin NU, Margolin K, Ahluwalia MS, Bendszus M, Chang SM, Dancey J, de Vries EGE, Harris GJ, Hodi FS, Lassman AB, Macdonald DR, Peereboom DM, Schiff D, Soffietti R, van den Bent MJ, Wefel JS, Wen PY. Addressing brain metastases from solid tumors within clinic trial designs for systemic agents: A guideline by the Response Assessment in Neuro-Oncology Brain Metastases (RANO-BM) working group. Lancet Oncol 19(1):e20-e32, 2018. e-Pub 2018. PMID: 29304358.
- Day J, Yust-Katz S, Cachia D, Wefel J, Katz LH, Tremont I, Bulbeck H, Armstrong T, Rooney AG. Interventions for the management of fatigue in adults with a primary brain tumour. Cochrane Database Syst Rev 4:CD011376. e-Pub 2016. PMID: 27074263.
- Joly F, Giffard B, Rigal O, De Ruiter MB, Small BJ, Dubois M, LeFel J, Schagen SB, Ahles TA, Wefel JS, Vardy JL, Pancré V, Lange M, Castel H. Impact of Cancer and Its Treatment on Cognitive Function: Advances in Research from the Paris International Cognition and Cancer Task Force Symposium and Update Since 2012. J Pain Symptom Manage 50(6):830-41, 2015. e-Pub 2015. PMID: 26344551.
- Lin NU, Wefel JS, Lee EQ, Schiff D, van den Bent MJ, Soffietti R, Suh JH, Vogelbaum MA, Mehta MP, Dancey J, Linskey ME, Camidge DR, Aoyama H, Brown PD, Chang SM, Kalkanis SN, Barani IJ, Baumert BG, Gaspar LE, Hodi FS, Macdonald DR, Wen PY, Neuro-Oncology group RAI. Challenges relating to solid tumour brain metastases in clinical trials, part 2: neurocognitive, neurological, and quality-of-life outcomes. A report from the RANO group. Lancet Oncol 14(10):e407-16, 2013. e-Pub 2013. PMID: 23993385.
Professional Educational Materials
- Wefel JS. Training Video and Website entitled, "Neurocognitive Test Battery". I authored and produced a training video that is used to teach standardized administration procedures for the core 'neurocognitive clinical trial battery' that is used in numerous cooperative group trials and sponsored trials for which I am the Neurocognitive Chair or consulting study neuropsychologist, 2007.
- Wefel JS. Neurocognitive Test Administration and Training Manual. I authored a manual that is used in conjunction with the Training Video to teach standardized administration procedures for the core 'neurocognitive clinical trial battery' that is used in numerous cooperative group trials and sponsored trials for which I am the Neurocognitive Chair or consulting study neuropsychologist, 2007.
Other Articles
- Gondi, V, Deshmukh, S, Brown, P, Wefel, JS, Armstrong, TS, Tomé, WA, Gilbert, MR, Konski, AA, Robinson, C, Bovi, J, Benzinger, TL, Roberge, D, Kundapur, V, Kaufman, I, Shah, SA, Usuki, K, Baschnagel, A, Mehta, MP, Kachnic, LA Erratum to. International Journal of Radiation Oncology Biology Physics 121(2):571-572, 2025. PMID: 39824575.
- Gondi V, Deshmukh S, Brown PD, Wefel JS, Armstrong TS, Tome WA, Gilbert MR, Konski A, Robinson CG, Bovi JA, Benzinger TLS, Roberge D, Kundapur V, Kaufman I, Shah S, Usuki KY, Baschnagel AM, Mehta MP, Kachnic LA Erratum to: Gondi V, Deshmukh S, Brown PD, et al. Sustained Preservation of Cognition and Prevention of Patient-Reported Symptoms With Hippocampal Avoidance During Whole-Brain Radiation Therapy for Brain Metastases: Final Results of NRG Oncology CC001. Int J Radiat Oncol Biol Phys. 2023;117:571-580. Int J Radiat Oncol Biol Phys 121(2):571-572, 2025. PMID: 39824575.
- Wefel J, Pugh S, Choucair A, Fisher B, Fox S, Meyers C, Ashby L, Mikkelsen T, Glass J, Yu M, Howard S, Movsas B, Mehta M NCOG-01. NEUROCOGNITIVE FUNCTION (NCF) AND QUALITY OF LIFE (QOL) RESULTS FROM A PHASE II STUDY OF TEMOZOLOMIDE-BASED CHEMORADIOTHERAPY REGIMEN FOR HIGH RISK LOW-GRADE GLIOMAS. Neuro Oncol 21(6):vi158-9, 2019.
- Wefel JS, Pugh S, Choucair A, Fisher B, Fox S, Meyers C, Ashby L, Mikkelsen T, Glass J, Yu M, Howard S, Movsas B, Mehta M NCOG-01. NEUROCOGNITIVE FUNCTION (NCF) AND QUALITY OF LIFE (QOL) RESULTS FROM A PHASE II STUDY OF TEMOZOLOMIDE-BASED CHEMORADIOTHERAPY REGIMEN FOR HIGH RISK LOW-GRADE GLIOMAS 21(6):vi158–9, 2019.
Editorials
- Neth, BJ, Wefel, JS, Nead, KT. Cognitive outcomes in prostate cancer treatment: insights from the ODENZA trial and future considerations. Translational Andrology and Urology 14(4):864-867, 2025. PMID: 40376525.
- Wefel JS, Meyers CA. Cancer as a risk factor for dementia: a house built on shifting sand. J Natl Cancer Inst 97(11):788-9, 2005. PMID: 15928294.
- Meyers CA, Wefel JS. The use of the mini-mental state examination to assess cognitive functioning in cancer trials: no ifs, ands, buts, or sensitivity. J Clin Oncol 21:3557-8, 2003. PMID: 12913103.
Abstracts
- Omuro, A, Wefel JS. Multicenter randomized phase II study of R-MPV-A chemoimmunotherapy with or without low-dose whole-brain radiotherapy for newly diagnosed primary CNS lymphoma: NRG/ RTOG 1114. EANO European Association of Neuro-Oncology. e-Pub 2025.
- Wefel JS, Sullaway C, Danielsen JT, Cobb C, Noll K, Bajaj S, Quarles CC, Mohamed RM, Giordano S, Kumar V, Hou P, Kundu S, Sulman E, Tsvetkov A, Hu J, Chung C, Cata J, Patil KR, Neth BJ. Predictors of Cognitive Changes in Older Women with Breast Cancer: Results from a Prospective Longitudinal Observational Trial. Presented at The 9th International Cognition and Cancer Task Force Conference, 2025. e-Pub 2025.
- Wefel JS, Noll K, Weiss H. An Exploratory Factor Analysis of the Beck Depression Inventory – Second Edition and Associations of Symptom Clusters with Biopsychosocial Factors and Quality of Life in Newly Diagnosed Primary Brain Tumor Patients. Presented at The International Neuropsychological Society, 2025. e-Pub 2025.
- Corn BW, Paulus R, Gondi V, Mehta MP, Fogh S, Wefel JS, Videtic GM, Sun A, Yoon H, Heinzerling JH, McGarry RC, Kundapur V, Devisetty K, Wu A, Kanner AA, Pugh SL, Movsas B, Kachnic LA. “Hope"Drives Quality of Life in Patients with Brain Metastases, But, the "Hope Center" Remains Elusive: An Analysis of NRG-CC003. Journal of Clinical Oncology 42(Suppl 16):12011-12011, 2024. e-Pub 2024.
- Cramer C, Wefel JS. A Single Arm, Pilot Study of Ramipril for Preventing Radiation-Induced Cognitive Decline in Glioblastoma Patients Receiving Brain Radiotherapy. 2024 ASCO Annual Meeting, 2024. e-Pub 2024.
- Abraham C, Pugh SL, Brown PD, Gondi V, Bovi JA, Robinson CG, Wefel JS, Roberge D, Kundapur V, Devisetty K, Shah SA, Usuki KY, Baschnagel AM, Stea B, Yoon HA, Li J, Laack NN, Jindal S, Borges M, Kachnic LA. RADT-01. Baseline Hippocampal Volume As A Predictor Of Neurocognitive Changes After WBRT Or HA-WBRT: Secondary Analysis Of NRG Oncology CC001. Neuro-Oncology 25(Supplement_5):v48, 2023. e-Pub 2023.
- Bradshaw ME, Wefel JS, Noll KR, Rao G, Ferguson SD, Tawbi H, Huse J, Johnson J, Court L, O’Brien B, Lang F, Ejezie L, Sullaway C, Thomas A, Suki D, Yeboa DN. NCOG-01. Baseline patient-reported outcomes in an ongoing phase-III trial of pre-operative SRS vs. post-operative SRS for brain metastases. Neuro-Oncology 25(Supplement_5):v213, 2023. e-Pub 2023.
- Noll KR, Chen HS, Bradshaw M, Wefel JS, Sullaway C, Thomas A, Kumar VA, Prabhu S, Liu HL. QOL-01. Variability in anxiety and depression symptoms after eloquent glioma resection is associated with changes in functional connectomic properties. Neuro-Oncology 25(Supplement_5):v248, 2023. e-Pub 2023.
- Noll KR, Chen H, Bradshaw ME, Wefel JS, Sullaway C, Thomas A, Kumar V, Prabhu SS, Liu HL. Variability In Anxiety And Depression Symptoms After Eloquent Glioma Resection Is Associated With Changes In Functional Connectomic Properties. Neuro-Oncology 25(Suppl 5):v248, 2023. e-Pub 2023.
- Sheppard DP, Goldberg M, McGranahan T, Graber JJ, Venur V, Figuracion KCF, Song YB, Wefel JS, Noll KR, Ferreira M, Halasz LM, Taylor LP. INNV-30.Development And Implementation Of A Novel, Brief Neurocognitive Screening And Rehabilitation Service In A Clinical Neuro-Oncology Setting. Neuro-Oncology 25(Supplement_5):v163, 2023. e-Pub 2023.
- Noll KR, Bradshaw M, Chen HS, Wefel JS, Sullaway C, Thomas A, Kumar VA, Prabhu S, Liu HL. QOL-04. Changes in functional connectivity after surgery are associated with decline in functional independence in patients with eloquent glioma. Neuro-Oncology 25(Supplement_5):v249, 2023. e-Pub 2023.
- Bovi JA, Pugh SL, Brown PD, Gondi V, Robinson CG, Wefel JS, Sabsevitz D, Sprenger MT, Kundapur V, Roberge D, Devisetty K, Shah SA, Usuki KY, Stea B, Yoon HA, Donnelly ED, Laack NN, Baschnagel AM, Paulus R, Kachnic LA. BIOM-03. Lack Of Correlation Of MR-Determined White Matter Injury(WMI)With Neurocognitive Function (NCF)6 Months Following WBRT+/-Hippocampal Avoidance(HA)+Memantine:Secondary Analysis Of NRG Oncology NRGCC001. Neuro-Oncology 25(Supplement_5):v4, 2023. e-Pub 2023.
- Lassman AB, Polley MC, Iwamoto FM, Sloan AE, Wang TJC, Aldape KD, Wefel JS, Gondi V, Gutierrez AN, Manasawala M, Gilbert MR, Sulman EP, Wolchok JD, Greene RM, Neil EC, Lukas RV, Goldlust SA, Snuderl M, Dignam JJ, Won M, Movsas B, Mehta MP. A NRG Oncology Study BN007: Randomized Phase II/III Trial Of Ipilimiumab (Ipi) Plus Nivolumab (Nivo) Vs. Temozolomide (TMZ) In MGMT-Unmethylated (uMGMT) Newly Diagnosed Glioblastoma (nGBM). Neuro-Oncology 25(Supplement_2):ii2, 2023. e-Pub 2023.
- Lassman AB, Polley MC, Iwamoto FM, Sloan AE, Wang TJC, Aldape KD, Wefel J, Gondi V, Gutierrez AN, Manasawala M, Gilbert MR, Sulman EP, Wolchok JD, Green RM, Neil E, Lukas RV, Goldlust SA, Snuderl M, Dignam JJ, Won M, Movsas B, Mehta M. PL02.3.A NRG Oncology Study BN007: Randomized phase II/III trial of ipilimiumab (Ipi) plus nivolumab (Nivo) vs. temozolomide (TMZ) in MGMT-unmethylated (uMGMT) newly diagnosed glioblastoma (nGBM). Neuro-Oncology 25(Supplement_2):ii2, 2023. e-Pub 2023.
- Phillips S, Burton EM, Kreidieh FY, Glitza IC, McQuade JL, Amaria RN, Diab A, Patel SP, Wong MK, Li J, Chung C, Milton DR, Malke J, Simon J, Wefel JS, Davies MA, Tawbi HA. Phase II study of nivolumab (nivo) in combination with relatlimab (rela) in patients (pts) with active melanoma brain metastases (MBM) 41(16), 2023. e-Pub 2023.
- Burton EM, Kreidieh FY, Glitza IC, McQuade JL, Amaria RN, Diab A, Patel SP, Wong MKK, Li J, Chung C, Milton DR, Malke J, Simon J, Wefel JS, Davies MA, Tawbi HA. Phase II study of nivolumab (nivo) in combination with relatlimab (rela) in patients (pts) with active melanoma brain metastases (MBM). 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
- Wefel JS, Noll KR, Rao G, Ferguson S, Tawbi H, Huse J, Johnson J, Court L, O/Brien B, Lang F, Ejezie L, Sullaway C, Thomas A, Suki D, Yeboa DN. Neurocognitive function and neurocognitive concerns in a phase III trial of pre-operative SRS versus post-operative SRS for brain metastases, 2023. e-Pub 2023.
- Lassman AB, Polley MC, Iwamoto FM, Sloan AE, Wang TJC, Aldape KD, Wefel J, Gondi V, Gutierrez AN, Manasawala M, Gilbert MR, Sulman EP, Wolchok JD, Green RM, Neil E, Lukas RV, Goldlust SA, Snuderl M, Dignam JJ, Won M, Movsas B, Mehta M. CTIM-18. NRG Oncology Study BN007: Randomized phase II/III trial of dual immune checkpoint blockade (ipilimiumab + nivolumab) vs. temozolomide in MGMT-unmethylated newly diagnosed glioblastoma. Neuro-Oncology 25(Supplement_5):v65-v65, 2023. e-Pub 2023.
- Gondi V, Pugh S, Mehta MP, Wefel JS, Tome WA, Sun AY, Videtic GNM, Lok B, Yoon HA, Heinzerling JH, DeNittis AS, McGarry RC, Devisetty K, Kundapur V, Wu A, Paulus R, Kachnic LA. Primary endpoint results of NRG CC003: Phase IIR/III trial of prophylactic cranial irradiation with or without hippocampal avoidance for small cell lung cancer. International Journal of Radiation Oncology, Biology, Physics 117(4):e3, 2023. e-Pub 2023.
- Eschler B, Bradshaw M, Wefel JS, Rexer J, Sullaway C, Noll K. Understanding Object Dysnomia in Patients With Left Hemisphere Primary Brain Tumors. Presented at the Biennial Meeting of the International Cognition and Cancer Task Force, San Diego, CA, January 30-31. 2023, 2023. e-Pub 2023.
- Catalino M, Noll K, Prabhu S, Wefel JS. Resting Motor Threshold is Associated with Neurocognitive Function and Supports Global Oscillatory State Alterations in Low Grade Glioma Patients. Presented at the Biennial Meeting of the International Cognition and Cancer Task Force, San Diego, CA, January 30-31. 2023, 2023. e-Pub 2023.
- Wefel JS, Sulman E, Tortarolo C, Sullaway C, Giordano S, Kumar V, Hou P, Hu J, Chung C, Cata J, Tsvetkov A, Kundu S. Cognitive Outcomes in Women Treated for HER2-negative Breast Cancer. Presented at the Biennial Meeting of the International Cognition and Cancer Task Force, San Diego, CA, January 30-31. 2023, 2023. e-Pub 2023.
- Sullaway CM, Li J, Sulman EP, Pezzi TA, Noll KR, Tortarolo C, Wefel JS. Neurocognitive decline in patients with 4-20 brain metastases treated with stereotactic radiosurgery. Presented at the Annual Mid-Year Meeting of the International Neuropsychological Society, Barcelona, Spain, July 6-8, 2022. e-Pub 2022.
- Weinberg JS, McAleer MF, Johnson JM, Kudchadker R, Wefel JS, Yuan Y, Lin HY. A phase III multi-center randomized controlled trial of postsurgical stereotactic radiotherapy versus surgically targeted radiation therapy (STaRT) for the treatment of large (>2.5cm) newly diagnosed brain metastases: Trial in progress. JCO 39:TPS2067-TPS2067, 2021. e-Pub 2021.
- Cramer CK, Page BR, Wefel JS, Dressler EV, Ip E, Rapp SR, Shaw EG, Weaver K, Lesser GJ, Chan MD. NCOG-24. Wake Forest NCORP Research Base feasibility study of ramipril for preventing cogntiive decline in glioblastoma patients receiving brain radiotherapy (WF-1801). Neuro Oncol 22(Suppl 2):ii134, 2020. e-Pub 2020.
- Omuro AMP, DeAngelis LM, Karrison T, Bovi JA, Rosenblum M, Corn BW, Correa D, Wefel JS, Aneja S, Grommes C, Schaff L, Waggoner SE, Lallana EC, Werner-Wasik M, Iwamoto F, Robinson TJ, Donnelly E, Struve T, Won M, Mehta MP. Randomized phase II study of rituximab, methotrexate (MTX), procarbazine, vincristine, and cytarabine (R-MPV-A) with and without low-dose whole-brain radiotherapy (LD-WBRT) for newly diagnosed primary CNS lymphoma (PCNSL). 2020 ASCO Virtual Scientific Program, Oral Abstract Session, J Clin Oncol 38:2020 (suppl; abstr 2501), 2020. e-Pub 2020.
- Beer TM, Shore ND, Morgans AK, Winters-Stone KM, Wefel JS, Ortiz JA, Reeves JA, George DJ. DaroACT: Darolutamide and enzalutamide effects on physical and neurocognitive function and daily activity in patients with castration-resistant prostate cancer (CRPC), 2020 ASCO Virtual Scientific Program, J Clin Oncol 38: 2020 (suppl; abstr TPS5587), 2020. e-Pub 2020.
- Li J, Wang Y, Tang C, Welsh JW, Guha-Thakurta N, Carter BW, Wefel JS, Ghia AJ, Yeboa D, McAleer MF, Chung C, Woodhouse KD, Elamin Y, Le Y, Cascone T, Negrao MV, Skoulidis F, Ferrarotto R, Heymach J, Altan M. Concurrent nivolumab and ipilimumab with brain stereotactic radiosurgery from brain metastases from non-small cell lung cancer: A phase I trial. 2020 ASCO Virtual Scientific Program, J Clin Oncol 38: 2020 (suppl; abstr 2531), 2020. e-Pub 2020.
- Wefel JS, Won M, Lassman AB, Stern Y, Wang TJC, Aldape K, Armstrong TS, Vogelbaum MA, Sulman EP, Moazami G, Macsai MS, Gilbert MR, Bain E, Blot V, Gan HK, Preusser M, Ansell PJ, Samanta S, Kundu MG, Seidel C, de Vos F, Hsu S, Cardona A, Lombardi G, Bentsion D, Peterson R, Gedye C, Lebrun-Frenay C, Wick A, Pugh S, Curran WJ, Mehta MP. Neurocognitive function (NCF) outcomes of RTOG Foundation 3508: A Phase 3 trial of ABT-414 with concurrent chemoradiation and adjuvant temozolomide in patients with EGFR-amplified newly diagnosed glioblastoma. 25th Annual Scientific Meeting of the Society for Neuro-Oncology, Austin, TX, November 18-22, 2020. e-Pub 2020.
- Wefel JS, DeMora L, Gond V, Tsien CI, Chenevert T, Gilbert MR, Omuro A, Cao Y, Srinivasan A, Rogers CL, Shi W Nedzi L, Chan MD, Suh JH, Battiste JD, Mishra M, Shivnani A, Movsas B, Mehta M. Neurocognitive function (NCF) of the Photon Cohort in NRG-BN001. 25th Annual Scientific Meeting of the Society for Neuro-Oncology, Austin, TX, November 18-22, 2020. e-Pub 2020.
- Jaeckle KA, Ballman KV, van den Bent M, Giannini C, Galanis E, Brown PD, Jenkins RB, Cairncross JG, Wick W, Weller M, Aldape KD, Dixon JG, Anderson JK, Cerhan JH, Wefel JS, Klein M, Grossman SA, Schiff D, Raizer JJ, Dhermain F, Nordstrom DG, Flynn PJ, Vogelbum MA. CODEL: Phase III study of RT alone, RT plus Temozolomide, or Temozolomide alone for newly-diagnosed 1P/19O codeleted anaplastic oligodendroglioma patients. Updated analysis from the initial study design. 25th Annual Scientific Meeting of the Society for Neuro-Oncology, Austin, TX, November 18-22, 2020. e-Pub 2020.
- Estevis E, Bradshaw ME, Wefel JS, Kesler Rexer J, Harmon CE, Rhines S, Noll K. Driver safety in patients with primary brain tumor 6(6):490-498, 2019. e-Pub 2019. PMID: 31832220.
- Al Feghali KS, Randall JW, Wefel JS, Guha-Thakurta N, Grosshans D, Dibaj S, McAvoy S, Li J, McGovern S, McAleer M, Ghia A, Paulino A, Sulman E, Penas-Prado M, Wang J, deGroot J, Heimberger A, Armstrong T, Gilbert M, Mahajan A, Brown PD, Chung C. Prospective Phase II Randomized Trial Comparing Proton Therapy vs. Photon IMRT for GBM: Secondary Analysis Comparison of Progression Free Survival Between RANO vs. Clinical and Radiological Assessment. Neuro-Oncology 21(6):vi161-vi162, 2019. e-Pub 2019.
- Majd N, Mastall M, Hess K, Fuller G, Alfaro-Munoz K, Gule-Monroe M, Huse J, Khatua S, Rao G, Sandberg DI, Wefel J, Yeboa D, Zaky W, Mahajan A, Puduvalli V, Suki D, Weathers S, Harrison R, deGroot J, Penas-Prado M. Characterization of Adult Medulloblastoma: A Retrospective Review of 200 Patients at MD Anderson Cancer Center. Neuro-Oncology 21(6):vi231-vi232, 2019. e-Pub 2019.
- Randall J, Al Feghali K, Wefel J, Grosshans D, Dibaji S, Milton D, McAvoy S, Li J, McGovern S, McAleer M, Ghia A, Paulino A, Sulman E, Penas-Prado M, Wang J, deGroot J, Heimberger A, Armstrong T, Gilbert M, Mahajan A, Brown P, Chung C. Prospective phase II Randomized Trial Comparing Proton Therapy vs. Photon IMRT for GBM: Secondary Analysis Comparison of Gender and Neutrophil-Lymphocyte Ratio (NLR) in GBM Outcomes. Neuro-Oncology 21(6):vi213, 2019. e-Pub 2019.
- Pollack A, Karrison TG, Balogh AG, Low D, Bruner DW, Wefel JS, Gomella LG, Martin AG, Michalski JM, Angyalfi S, Lukka H, Faria SL, Rodrigues G, Beauchemin MC, Lee RJ, Seaward SA, Allen AM, Monitto DC, Seiferheld W, Sandler HM. MP72-01. Improvements in freedom from progression with short term androgen deprivation therapy and pelvic lymph node treatment added to prostate bed salvage radiotherapy: The NRG Oncology/RTOG 0534 SPPORT Trial. The Journal of Urology 201:e1054-1055, 2019. e-Pub 2019.
- Gondi V, Deshmukh S, Brown PD, Wefel JS, Tome WA, Armstrong T, Bruner D, Bovi JA, Robinson CG, Khuntia D, Grosshans DR, Konski AA, Roberge D, Kundapur V, Devisetty K, Shah SA, Usuki K, Anderson BM, Mehta MP, Kachnic LA. NRG Oncology CC001: A phase III trial of hippocampal avoidance (HA) in addition to whole-brain radiotherapy (WBRT) plus memantine to preserve neurocognitive function (NCF) in patients with brain metastases (BM). JCO 37:2009-2009, 2019. e-Pub 2019.
- Gondi V, Deshmukh S, Brown PD, Wefel JS, Tome WA, Armstrong T, Bruner D, Bovi JA, Robinson CG, Khuntia D, Grosshans DR, Konski AA, Roberge D, Kundapur V, Devisetty K, Shah SA, Usuki K, Anderson BM, Mehta MP, Kachnic LA. NRG Oncology CC003: A randomized phase II/III trial of prophylactic cranial irradiation with or without hippocampal avoidance for small cell lung cancer. JCO 37:TPS8578-TPS8578, 2019. e-Pub 2019.
- Gondi V, Deshmukh S, Brown PD, Wefel JS, Tome WA, Bruner DW, Bovi JA, Robinson CG, Khuntia D, Grosshans DR, Konski AA, Roberge D, Kundapur V, Devisetty K, Shah SA, Usuki KY, Anderson BM, Mehta MP, Kachnic LA. NCOG-01. Preservation of neurocognitive function with conformal avoidance of the hippocampus during whole-brain radiotherapy (HA-WBRT) for brian metastases: Preliminary results of phase III trial NRG Oncology CC001. Neuro Oncol 20(Suppl 6):vi172, 2018. e-Pub 2018.
- Sheppard DP, Noll K, Wefel JS. NCOG-05. Intra-individual neurocognitive variability in patients with cancer: a predictor and marker of neurotoxicity associated with chemotherapy. Neuro-Oncology 20(suppl_6):vi173, 2018. e-Pub 2018.
- Mastall M, Majid N, Fuller G, Gule-Monroe M, Huse J, Khatua S, Rao G, Sandberg D, Wefel J, Yeboa D, Zaky W, Mahajan A, Puduvalli V, Suki D, Alfaro K, Weather S, Harrison R, de Groot J, Penas-Prado M. Adult medulloblastoma: analysis of use of chemotherapy in clinical practice. Neuro Oncol 20(Suppl 3):iii325, 2018. e-Pub 2018.
- Wefel JS, Deshmukh S, Brown PD, Grosshans DR, Sulman EP, Cerhan JH, Mehta MP, Khuntia D, Shi W, Mishra MV, Suh JH, Laack NN, Chen Y, Curtis A, Laba JM, Mowat RB, Thakrar A, Pugh SL, Brunner DW. Impact of Appolipoprotein E (APOE) genotype on neurocognitive function (NCF) in patients with brain metastasis (BM): An analysis of NRG Oncology's RTOG 0614. Int J Radiat Oncol Biol Phys 119(3):846-857, 2018. e-Pub 2018. PMID: 38101486.
- Mastall M, Majid N, Fuller G, Gule-Monroe M, Huse J, Khatua S, Rao G, Sandberg D, Wefel J, Yeboa D, Zaky W, Mahajan A, Puduvalli V, Suki D, Alfaro K, Weather S, Harrison R, de Groot J, Penas-Prado M. Characterization of adult medulloblastoma patients at recurrence: retrospective review of the MD Anderson experience. Neurooncol Adv 5(1):vdad032, 2018. e-Pub 2018. PMID: 37114244.
- Pollack A, Karrison TG, Balogh AG, Low D, Bruner DW, Wefel JS, Gomella LG, Vigneault E, Michalski JM, Angyalfi S, Lukka H, Faria SL, Rodrigues G, Beauchemin MC, Seaward SA, Allen AM, Monitto DC, Seiferheld W, Sandler HM. Short Term Androgen Deprivation Therapy Without or With Pelvic Lymph Node Treatment Added to Prostate Bed Only Salvage Radiotherapy: The NRG Oncology/RTOG 0534 SPPORT Trial. International Journal of Radiation Oncology, Biology, Physics 102(5):1605, 2018. e-Pub 2018.
- Schvartsman G, Glitza IC, Milton D, Amaria RN, Hwu P, Hwu W, Diab A, Wong MK, Patel SP, Wefel JS, Burton EM, Brown C, Woodman SE, Beosch IM Chung C, Davies MA, Tawbi HA. A phase II study of bevacizumab (BEV) in combination with atezolizumab (ATEZO) in patients with untreated melanoma brain metastases (BEAT-MBM):TPS9598-TPS9598, 2018. e-Pub 2018. PMID: 36.
- Wefel JS, Tortarolo C, Giordano S, Rao V, Sulman E, Hou P, Kumar A, Kumar V, Kesler S. Subcomponent processes underlying learning and memory decline associated with cancer and cancer therapy in women with breast cancer, 2018. e-Pub 2018.
- Salek KE, Hassan IS, Faro SH, Mohamed FB, Zinn PO, Wei A, Li N, Kumar AJ, Weinberg JS, Wefel JS, Abrol S, Kesler SR, Liu HA, Hou P, Stafford RJ, Prabhu S, Sawaya R, Colen RR. Silence Sentence Completion Paradigm Shows Superiority in Localization of Wernicke's Area and Changes in Functional Activation in the Distinct Language Paradigms Correlate with Key Genomic Markers: A Prospective Study 7(1):12054, 2017. e-Pub 2017. PMID: 28935966.
- Harrison RA, Sullaway CM, Kesler SR, Johnson JM, Wefel JS. Neurocognitive Profiles of Adults with Cerebellar Medulloblastoma. Neurology 88(Suppl 16), 2017. e-Pub 2017.
- Wefel JS, Patwardhan SY, Bradshaw ME, Massman PJ. Validity and diagnostic accuracy of the clinical trial battery in patients with primary brain tumor, 2017. e-Pub 2017.
- Verhaak AS, Arbona CA, Day SX, Wefel JS. Prediction of subjective memory ability and patient self-report accuracy before resection of high grade glioma, 2017. e-Pub 2017.
- Moruno Manchon JF, Dabaghian Y, Uzor NE, Kesler SR, Wefel JS, Tsvetkov AS. Levetiracetam mitigates doxorubicin-induced DNA and synaptic damage in neurons. Sci Rep 6:25705, 2016. e-Pub 2016. PMID: 27168474.
- Jaeckle K, Vogelbaum M, Ballman KV, Anderson SK, Giannini C, Aldape K, Cerhan J, Wefel JS, Nordstrom D, Jenkins R, Klein M, Raizer J, Van Den Bent M, Wick W, Flynn P, Dhermain F, Cairncross, Galanis E, Brown P. CODEL (Alliance –N0577; EORTC-26081/22086; NRG-1071; NCIC-CEC-2); Phase III Randomized Study of RT vs RT+TMZ vs TMZ for Newly Diagnosed 1p/19q-Codeleted Anaplastic Oligodentroglial Tumors, Analysis of Patients Treated on the Original Protocol Design. Neurology 86(Suppl 16):PL02.005, 2016. e-Pub 2016.
- Kesler SR, Tortarolo C, Giordano SH, Hou P, Kumar AJ, Jones JR, Jackson E, Wefel JS. Longitudinal Changes in Brain Network Local Efficiency and Verbal Memory Performance Following Breast Cancer Chemotherapy, 2016. e-Pub 2016.
- Hansen CC, Chrane K, Gunn GB, Mohamed ASR, Rosenthal DI, Wefel JS, Phan J, Frank SJ, Garden AS, Smith B, Eichelberger H, Anderson C, McCoy C, Horiates M, Patrick C, Floris S, French C, Beadle BM, Morrison WH, Su SY, Hanna EY, Lewis CM, Skinner HD, Lai S, Fuller CD. Cognitive function and patient-reported memory problem following radiation therapy for cancers at the skull base: A survivorship study using the Telephone Interview for Cognitive Status and the MDASI-HN. IJROBP 94(4):967, 2016. e-Pub 2016.
- Vera E, Scheurer ME, Zhou R, Acquaye A, Berger A, Breton G, Mahajan A, Wefel J, Gilbert MR, Amstrong TS. Investigation of risk factors associated with fatigue in glioma patients. JCO 34:2018-2018, 2016. e-Pub 2016.
- Demeriva P, Noll KR, Sellin J, Prabhu S, Wefel J. Neurocognitive changes associated with frontal lobectomy for right and left frontal lobe glioma. Neuro Oncol 17(Suppl 5):v148-9, 2015. e-Pub 2015.
- Wefel JS, Bradshaw ME, Sullaway CM, Gilbert MR, Armstrong TS. NCO-17: A brain-plasticity based computerized intervention to treat attention and memory problems in adult brain tumor (BT) survivors. Neuro Oncol 17(Suppl 5):v149-50, 2015. e-Pub 2015.
- Verhaak AS, Arbona CA, Day SX, Wefel JS. Prediction of subjective memory ability before resection of high grade glioma. Neuro Oncol 17(Suppl 5):v149, 2015. e-Pub 2015.
- Kesler S, Noll K, Cahill D, Rao G, Wefel J. NIMG-42: Lower brain network efficiency in IDH1 wild type (IDH1-WT) malignant astrocytoma compared to IDH1 mutant (IDH1-M). Neuro Oncol 17(Suppl 5):v163, 2015. e-Pub 2015.
- Wefel JS, Sulman EP, Zhou R, Liu Y, Scheurer ME, Bondy ML. Genetic modulation of neurocognitive decline in glioma patients. Clin Cancer Res 21(14):3340-6, 2015. e-Pub 2015. PMID: 25904748.
- Noll, KR, Narang S, Martinez J, Rao G, Wefel J, Rao A. Relationships between tumor compartment volumes and neurocognitive functioning in patients with temporal lobe glioma. Neuro Oncol 17(Suppl 5):580-7, 2015. e-Pub 2015. PMID: 25227126.
- Mehta MP, Gondi V, Pugh SL, Tome WA, Wefel JS, Fogh SE, Movsas B, Konski AA, Lassman AB, Robinson CF, Bovi JA, Benzinger TLS, Redmond KJ, Sun A, Bruner DW. NRG-CC003: Randomized Phase II/III Trial of Prophylactic Cranial Irradiation with or without Hippocampal Avoidance for Small Cell Lung Cancer, 2015. e-Pub 2015.
- Noll KR, Narang S, Martinez J, Rao G, Wefel J, Rao A. Tumor volumetric and textural feature predictors of neurocognitive impairment in patients with temporal lobe glioma. Neuro Oncol 17(Suppl 5):v148, 2015. e-Pub 2015.
- Noll KR, Wang X, Shi Q, Wefel J. Neurocognitive functioning, gender, and inflammatory markers in patients with colorectal cancer prior to chemotherapy. Journal of the International Neuropsychological Society 21(Suppl 1):292, 2015. e-Pub 2015.
- Noll K, Garbarino A, Turner C, Verhaak AMS, Wefel J. Depression and executive function in relation to survival in patients with glioblastoma. Neuro Oncol 16(Suppl 5):v136, 2014. e-Pub 2014.
- Wefel J, Noll K, Rao G, Cahill D. Relationships between neurocognitive functioning and IDH1 genetic mutation status in malignant astrocytoma. Neuro Oncol 16(Suppl 4):580-7, 2014. e-Pub 2014. PMID: 25227126.
- Kesler, SR, Wefel. Default mode network connectivity as a potential biomarker of chemotherapy-related cognitive deficit 35(Suppl 2):S11-9, 2014. e-Pub 2014. PMID: 24913897.
- Turner C, Noll K, Strange C, Bradshaw M, Wefel JS. Quality of life, mood, and neurocognitive functioning in patients with temporal lobe glioma. Neuro-Oncology 15(Suppl 3):iii96, 2014. e-Pub 2014.
- Wefel JS, Noll K, Rao G, Cahill D. NC-15: Relationships between neurocognitive functioning and IDH1 genetic mutation status in malignant astrocytoma. Neuro Oncol 16(Suppl 5):v137, 2014. e-Pub 2014.
- Noll K, Turner C, Garbarino A, Wefel JS. Relationships between tumor grade and neurocognitive functioning in patients with glioma of the left temporal lobe. Poster session presented at the Cancer Survivorship Research Symposium, The University of Texas M. D. Anderson Cancer Center, Houston, 2014. e-Pub 2014.
- Noll K, Weinberg J, Ziu M, Turner C, Strange C, Wefel JS. Verbal learning and encoding strategies in patients with glioma of the right and left temporal lobes. Neuro-Oncology 15(Suppl 3):iii92-iii97, 2013. e-Pub 2013.
- Taychakhoonavudh S, Franzini L, Lal L, Chang E, Meyers CA, Wefel JS, Swint JM. Comparision of Patients Reported Outcomes (PROS) and Clinician Reported Outcomes (CROS) in Patients with Metastastic Brain Disease. Value in Health 16(3):A145-A146, 2013. e-Pub 2013.
- Bradshaw ME, Noll K, Ziu M, Weinberg J, Strange C, Turner C, Wefel JS. Neurocognitive functioning and functional status in patients with glioma of the temporal lobes. Neuro-Oncology 15(Suppl 2):iii92, 2013. e-Pub 2013.
- Ziu M, Noll K, Weinberg, J, Benveniste R, Turner C, Strange C, Suki D, Wefel JS. Neurocognitive functioning in patients with glioma of the right and left temporal lobes. Neuro-Oncology 15(Suppl 3):iii97, 2013. e-Pub 2013.
- Resendiz CV, Armstrong TS, Acquaye A, Vera-Bolanos E, Gilbert M, Wefel JS. When do patients/caregive report of cognitive symptoms predict neurocognitive dysfunction?, 2013. e-Pub 2013.
- Turner C, Strange C, Bradshaw M, Noll K, Wefel JS. Quality of life, mood, and neurocognitive functioning in patients with temporal lobe glioma. Neuro-Oncology 15(Suppl 3):iii96, 2013. e-Pub 2013.
- Gning I, Armstrong TS, Wefel JS, Acquaye AA, Vera-Bolanos E, Tito R, Mendoza TR, Gilbert MR, Cleeland CS. Assessing The Validity of the MD Anderson Symptom Inventory-Brain Tumor (MDASI-BT) Using Caregiver Proxy Report, 2012. e-Pub 2012.
- Gehring K, Sawyer AM, Etzel CJ, Lang FF, Wefel JS. NC-11. Prediction of Memory Outcomes after Resection of High Grade Glioma. Neuro-Oncology 13(Suppl 3):75-75, 2011. e-Pub 2011.
- Wefel JS, Patwardhan SY, Strange C. Concurrent and criterion validity related evidence for the neurocognitive function clinical trial battery in brain tumor patients. Neuro-Oncoloy 12(4):iv58-iv61, 2010. e-Pub 2010.
- Patwardhan S, Fitzgerald K, Meyers C, Wefel J. Comparison of Trail Making Tests A and B Standard Scores Based on Heaton and Tombaugh Systems, 2010. e-Pub 2010.
- Patwardhan SY, Teo I, Wefel JS, Levin VA. Quality of life associated with tumor laterality among hypothyroid patients with primary brain tumors receiving thyroid hormone supplements, 2010. e-Pub 2010.
- Patwardhan SY, Myszka KA, Collins R, Etzel CJ, Meyers CA, Wefel JS. Assessment of the Efficacy of Immediate Release Methylphenidate, Sustained Release Methylphenidate, and Modafinil for Patients with Primary Brain Tumor, 2010. e-Pub 2010.
- Wefel JS, Patwardhan S, Levin VA. Neurocognitive outcomes associated with combined levothyroxine/liothyronine supplementation in hypothyroid patients with primary brain tumors 11(5):642, 2009. e-Pub 2009.
- Armstrong TS, Wefel JS, Gning I, Vera-Bolanos E, Acquaye A, Mendoza T, Gilbert MR, Kayl AE, Cleeland C. Congruence of Caregiver and Patient Symptom Report and Association with Patient Neurocognitive Status. Presented as an Oral Presentation at the 2009 Joint Meeting of the Society for Neuro-Oncology and AANS/CNS Section on Tumors. Neuro-Oncology 11(5):562, 2009. e-Pub 2009.
- Vredenburgh JJ, Wefel J, Cloughesy T, Zazzali J, Samant M, Zheng M, Fang L, Das A, BRAIN Investigators FHFT. 8707 Clinical Assessment of Corticosteroid Use and Neurocognitive Function in Patients with Glioblastoma at First or Second Relapse Treated with Bevacizumab in the BRAIN Study. European Journal of Cancer Supplements 7(2):495-496, 2009. e-Pub 2009.
- Wefel J, Cloughesy T, Zazzali J, BRAIN Investigators FHFT. Neurocognitive function in patients with glioblastoma multiforme in first or second relapse treated with bevacizumab in the BRAIN study. JCO 27 27(Suppl 15):2056-2056, 2009. e-Pub 2009.
- Witgert M, Chang E, Wefel J. Acute effects of stereotactic radiosurgery +/- whole brain radiation therapy on fatigue in patients with brain metastases, 2008. e-Pub 2008.
- Veramonti T, Wefel J. Neurocognitive Interventions for Brain Tumor Patients Case Report, 2008. e-Pub 2008.
- Witgert M, Lang F, Suki D, Chang E, Meyers C, Wefel J. Baseline cognitive impairment in patients with single brain metastasis, 2007. e-Pub 2007.
- Benveniste RJ, Wefel JS, Meyers CA, Hlatky R, Weinberg JS. Neurocognitive Deficits Following Resection of Right Temporal Lobe Gliomas, 2007. e-Pub 2007.
- Kim SS, McCutheon IE, Sawaya R, Weinberg JS, Lang FF, Heimberger AB, DeMonte F, Hassenbusch SJ, Rhines L, Ferson DZ, Wefel JS, Suki D, Prabhu SS. Awake Craniotomy for Brain Tumors Near Eloquent Cortex: Correlation of Intraoperative Cortical Mapping with Neurological Outcomes in 300 Consecutive Patients, 2007. e-Pub 2007. PMID: 19404147.
- Veratmonti TL, Pappas C, Meyers CA, Wefel JS. Factor Analysis of the Functional Assessment of Cancer Therapy - Brain module in a Primary Brain Tumor Population at Time of Diagnosis, 2007. e-Pub 2007.
- Wefel JS, Veramonti TL, Bruera E, Davenport SD, Meyers CA. Cognitive Outcomes of a Pilot Trial Examining Donepezil for the Treatment of Opioid-induced Sedation in Cancer Patients, 2007. e-Pub 2007.
- Ferson D, Chi L, Jackson E, Meyers C, Mahankali S, Wefel J, Sawaya R. Correlation of Preoperative fMRI with Intraoperative Speech Mapping in a Trilingual Patient. Journal of Neurosurgical Anesthesiology 18(4):275-276, 2006. e-Pub 2006.
- Wefel JS, Meyers CA. “Chemobrain?” Pre-chemotherapy cognitive impairment in women with breast cancer 101(3):466-475, 2004. e-Pub 2004.
- Wefel JS, Meyers CA. Tamoxifen associated neurotoxicity in women with breast cancer, 2004. e-Pub 2004.
- Chang E, Wefel JS, Meyers CA, Mahajan A, Mathews LA, Smythe L, Allen PK, Hassenbusch SJ, Maor MH. Prospective Neurocognitive Evaluation of Patients with 1 to 3 Newly Diagnosed Brain Metastases Treated with Stereotactic Radiosurgery Alone. International Journal of Radiation Oncology, Biology, Physics 60(1):S164-165, 2004. e-Pub 2004.
- Wefel JS, Lang F, Nader R, Meyers CA. Neurocognitive sequelae of surgical resection for previously untreated intrinsic insular region tumor. Neuro-Oncology 5:335, 2003. e-Pub 2003.
- Sander AM, Wefel JS, High WM, Contant C. Impact of family functioning on community integration after TBI. Journal of the International Neuropsychological Society 7(2):178, 2001. e-Pub 2001.
- High WM, Wefel JS, Sander AM, Boake C, Robinson K, Contant C, Hannay HJ. Comparison of the Glasgow Outcome Scale and Disability Rating Scale as a measure of outcome after TBI. Journal of the International Neuropsychological Society 7:175, 2001. e-Pub 2001.
- Wefel J, Meyers CA. Qualitative performance on the Benton Visual Retention Test in patients with primary brain tumors. J International Neuropsychological Society 7:253, 2001. e-Pub 2001.
- Cole L, Glosser G, Hiscock M, Wefel JS. Implications for mesial temporal lobe involvement in memory retrieval: evidence from temporal lobectomy, 2000. e-Pub 2000.
- Sander AM, High WM, Wefel JS, Contant C. Dimensions of family response to TBI: Relationship to patient outcome. Archives of Physical Medicine and Rehabilitation 81:1621, 2000. e-Pub 2000.
- Wefel JS, Friedman MA, Meyers CA. Benton Visual Retention Test performance in patients with primary brain tumors. Journal of the International Neuropsychological Society 5:141, 1999. e-Pub 1999.
- Mochache M, Bradshaw ME, Prabhu SS, Wefel JS, Noll KR. Prediction of Baseline and Postoperative Change in Verbal Episodic Memory from Learning Characteristics in Patients with Glioma Undergoing Awake Craniotomy. Accepted for presentation at the 54th Annual North American Meeting of the International Neuropsychological Society.
- Wefel JS, Noll KR, Rao G, Ferguson S, Tawbi H, Huse J, Johnson J, Court L, O/Brien B, Lang F, Ejezie L, Sullaway C, Thomas A, Suki D, Yeboa DN. Neurocognitive function and neurocognitive concerns in a phase III trial of pre-operative SRS versus post-operative SRS for brain metastases. Presented at the 2023 SNO/ASCO Cancer Conference.
- Gondi V, Pugh S, Mehta MP, Wefel JS, Tome WA, Sun A, Videtic GM, Lok BH, Yoon HA, Heinzerling JH, DeNittis AS, McGarry RC, Devisetty K, Kundapur V, Wu AJ, Paulus R, Kachnic LA. Primary endpoint results of NRG CC003: Phase IIR/III trial of prophylactic cranial irradiation (PCI) with or without hippocampal avoidance (HA) for small cell lung cancer (SCLC). 2023 ASTRO Annual Meeting.
- Bajaj S, Quarles CC, Giordano S, Kumar V, Hou P, Kundu S, Sulman E, Tsvetkov A, Hu J, Chung C, Cata J, Noll K, Sullaway C, Patil K, Wefel JS. The Neurobiological Footprint of Breast Cancer Chemotherapy: Gray Matter Changes and Signs of Accelerated Brain Aging. Oral presentation, Meeting of the International Neuropsychological Society.
- Danielsen JTT, Zachariae R, Schmidt H, Kallehauge JF, Thomasdsen JK, Wefel JS, Wu LM, Amidi A. Cognition and cerebral gray matter in patients with melanoma undergoing adjuvant immunotherapy. Poster presentation, Meeting of the International Cognition and Cancer Task Force.
- Neth B, Nguyen A, Raghunathan A, Ghaffar U, Alden E, Botha H, Ramanan V, Petersen R, Jack C, Knopman D, Ruddy K, Childs D, Karnes J, Wefel JS, Vemuri P, Graff-Radford J. Assessment of Alzheimer's disease neuropathologic change in cognitively impaired prostate cancer survivors. Oral presentation, Meeting of the International Cognition and Cancer Task Force.
- Tasnim I, Asman P, Swamy C, Connelly K, Muir M, Hall M, Wefel JS, Bajaj S, Pellizzer G, Ince N, Prabhu S, Noll K. Relationships between intraoperative gamma band electrocorticograms, direct electrical stimulation, and cognitive-linguistic outcomes in patients with language-eloquent brain tumors. Poster presentation, Meeting of the International Cognition and Cancer Task Force.
- Diaz Escarcega R, Wefel JS, Morales R, Tsvetkov A. Methotrexate upregulates indoleamine 2, 3-dioxygenase 1 in neurons and exacerbates disease phenotypes in a model of Alzheimer's disease. Poster presentation, Meeting of the International Cognition and Cancer Task Force.
- Noll K, Muir M, Prinsloo S, Michener H, Asman P, Kumar V, Bradshaw M, Wefel JS, Liu HL, Taylor B, Prabhu S. Influence of tractography seeding and thresholding upon relationships between surgical trauma to white matter tracts and postoperative neurocognitive outcome following resection of language-eloquent glioma. Oral presentation, Meeting of the International Cognition and Cancer Task Force.
- Bajaj S, Quarles CC, Sullaway C, Danielsen JT, Mohamed RM, Giordano S, Kumar V, Hou Ping, Kundu S, Sulman E, Tsvetkov A, Hu J, Chung C, Cata J, Noll K, Cobb C, Patil KR, Neth BJ, Wefel JS. Accelerated Brain Aging in Breast Cancer Survivors: Grey Matter Alterations Post- Chemotherapy and Their Association with Cognitive Function. Poster presentation, Meeting of the International Cognition and Cancer Task Force.
- Mochache M, Bradshaw ME, Prabhu SS, Wefel JS, Noll KR. Relationships between single trial learning and baseline and preoperative change in verbal episodic memory in eloquent glioma patients. Presented at the Houston Neuropsychological Society Annual Symposium.
- Bradshaw ME, Noll KR, Goethe E, Srinivasan S, Prabhu SS, Weinberg JS, McCutcheon IE, Lang FF, Wefel JS, Ferguson SD. Neurocognitive outcomes after resection of left inferior parietal lobule gliomas. Accepted for presentation at the 30th Annual Meeting of the Society for Neuro-oncology.
- Wefel JS, Noll KR, Sullaway CM, Bradshaw ME. Breast cancer survivors exhibit elevated rates of inattention and poor vigilance on the Conners’ Continuous Performance Test-3. Accepted for presentation at the 54th Annual North American Meeting of the International Neuropsychological Society.
Book Chapters
- Al Feghali KA, Bradshaw ME, Chung C, Wefel JS. Neurocognitive Effects on Brain Metastases and Their Treatment. In: Central Nervous System Metastases: Diagnosis and Treatment. Springer Nature, 2020.
- Gehring K, Kiaver K, Edwards ML, Kesler S, Wefel JS. Cognitive Rehabilitation in Patients with Non-Central Nervous System Cancer and Brain Tumors. In: Cognitive Rehabilitation and Neuroimaging: Examining the Evidence from Brain to Behavior. Springer, 2020.
- Sabsevitz DS, Elverman KH, Wefel J, Noll K. Neuropsychologist's Role in the Management of Brain Tumor Patients. In: Brain Mapping: Indications and Techniques. Thieme, 2020.
- Noll K, Sabsevitz D, Prabhu S, Wefel J. Neuropsychology in the Neurosurgical Management of Primary Brain Tumors. In: Neurosurgical Neuropsychology: The application of neuropsychology to the practice of neurosurgery. Elsevier, 2019.
- Bradshaw ME, Wefel JS. Neuropsychological Assessment of Older Adults with a History of Cancer. In: Handbook on the Neuropsychology of Aging and Dementia. 2nd. Springer, 2018.
- Kesler SR, Wefel JS. Targeted Treatment for Cognitive Impairment Associated with Cancer and Cancer Treatment. In: Working to Better the Brain: Clinical Scientific Research on Cognitive Enhancement. Oxford University Press, 2018.
- Brown PD, Schagen SB, Wefel JS. Cognitive Function in Cancer Patients. In: DeVita, Hellman, and Rosenberg's Cancer Principles and Practices of Oncology. 10th. Lippincott, Williams & Wilkins, 2015.
- Witgert ME, Wefel JS. The Neuropsychology of Oncology. In: Clinical Neuropsychology: A Pocket Handbook for Assessment. 3rd. APA, 2014.
- Cohen MZ, Shonka NA, Armstrong TS, Wefel JS. Cognitive Dysfunction. In: Cancer Symptom Management. 4th. Jones and Bartlett Learning, 2014.
- Noll KR, Wefel JS. Quality of Life and Neurocognitive Function. In: Neuro-Oncology: The Essentials. 3rd. Thieme Medical Publishers, Inc, 2014.
- Witgert ME, Wefel JS. Neuropsychological Assessment of Older Adults with a History of Cancer. In: Handbook on the Neuropsychology of Aging and Dementia. Springer, 443-454, 2013.
- Witgert ME, Wefel JS. Neurobehavioral Side Effects of Cancer and Cancer Therapy. In: MD Anderson Manual of Psychosocial Oncology. McGraw-Hill, 179-188, 2011.
- Meyers CA, Wefel JS. Cognitive Dysfunction. In: Cancer Symptom Science. Cambridge University Press, 51-59, 2011.
- Brown PD, Laack NN, Wefel JS. Neurocognitive Effects. In: DeVita, Hellman, and Rosenberg's Cancer: Principles and Practices of Oncology. 9th. Lippincott, Williams & Wilkins, 2011.
- Wefel JS, Armstrong TA, Kohli S. Neuropsychological Function, Symptom Measurement and Quality of Life in Brain Tumor Patients. In: Primary CNS Tumors: Pathogenesis and Therapy. Humana Press/Springer, 2010.
- Kayl AE, Collins RL, Wefel JS. Neuropsychological Assessment of Adults with Cancer. In: Cognition and Cancer. Cambridge University Press, 2009.
- Smith JA, Wefel JS. Neurocognitive Testing in Clinical Trials. In: Cognition and Cancer. Cambridge University Press, 2009.
- Wefel JS, Collins RL, Kayl AE. Chemotherapy and Biological Response Modifier-Related Cognitive Dysfunction. In: Cognition and Cancer. Cambridge University Press, 2009.
- Meyers CA, Wefel JS. Quality of Life. In: Neuro-Oncology: The Essentials, 2nd Edition. M Bernstein, MS Berger, 2008.
- Burton AW, Veramonti TL, Phan PC, Wefel JS. Symptom Management for Patients with Brain Tumors: Improving Quality of Life. In: MD Anderson Cancer Center Series: Tumors of the Brain and Spine. Springer, 2007.
- Wefel JS Janus T. Neurology and Neuropsychology in Oncology. In: Principles and Practice of Behavioral Neurology and Neuropsychology. P.M. Gordon Associates, Inc, 2003.
- Bradshaw ME, Wefel JS. Cancer and Cognition. In: Neuropsychology of Alzheimer's Disease and Other Dementias. 2nd. Oxford University Press.
- Al Feghali KA, Chung C, Wefel JS, Bradshaw. Neurocognitive Toxicity from Radation Therapy for Brain Metastases. In: Central Nervous System Metastases. Springer Nature.
Books (edited and written)
- . Cancer, Cancer Therapy and Nervous System Toxicity. Springer Publishing Company.
Letters to the Editor
- Wefel JS, Noll KR, Rao G, Cahill DP. Reply to Freyschiag et al. Neuro Oncol, 2017.
- Gilbert MR, Dignam J, Pugh S, Armstrong TS, Wefel JS, Aldape K, Stupp R, Hegi M, Won M, Curran WJ, Mehta MP. Reply to M. C. Chamberlain. J Clin Oncol 32: 1634-5, 2014.
- Welsh JW, McGovern SL, Wefel JS, Komaki R, Brown PD, Soh HE. Reply to V. R. Bhatt et al and M. C. Chamberlain. Journal of Clinical Oncology 31: 3165-6, 2013.
- Wefel JS, Meyers CA. Reply to Acute and late onset cognitive dysfunction associated with chemotherapy in women with breast cancer. Cancer 117: 1103-4, 2011.
- Wefel JS, Meyers CA. Response to Heflin et al. Journal of the National Cancer Institute 97: 1551-1552, 2005.
- Wefel JS, Meyers CA, Davis RN. Reply to Maruff et al. Cancer 101: 2144-2145, 2004.
Patient Reviews
CV information above last modified March 23, 2026