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Jeffrey S. Wefel

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Neuro-Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

2002 University of Houston, Houston, TX, PhD, Clinical Psychology
2000 University of Houston, Houston, TX, Master of Arts, Psychology
1994 Valparaiso University, Valparaiso, IN, BS, Psychology

Postgraduate Training

8/2002-12/2004 Neuropsychology Fellowship, UT M.D. Anderson Cancer Center, Houston, TX
7/2001-7/2002 Clinical Neuropsychology, University of Chicago Medical Center, Chicago, IL

Honors and Awards

2004-2006 National Institutes of Health Clinical Research, National Institutes of Health Clinical Research Loan Repayment Program
2003 Muriel D. Lezak Research Award, The Houston Neuropsychological Society
2002 Muriel D. Lezak Research Award, The Houston Neuropsychological Society
2001 Shell Foundation Graduate Scholarship, University of Houston
1996 Stella E. Cullen Scholarship, University of Houston

Selected Publications

Peer-Reviewed Original Research Articles

1. Wefel JS, Witgert ME, Meyers CA. Neuropsychological sequelae of non-central nervous system cancer and cancer therapy. Neuropsychol Rev 18(2):121-31, 6/2008. e-Pub 4/16/2008. PMID: 18415683.
2. Groves MD,Glantz MJ,Chamberlain MC,Baumgartner KE,Conrad CA,Hsu S,Wefel JS,Gilbert MR,Ictech S,Hunter KU,Forman AD,Puduvalli VK,Colman H,Hess KR,Yung WKA. A multicenter Phase II trial of intrathecal topotecan in patients with meningeal malignancies. Neuro Oncol 10(2):208-15, 4/2008. e-Pub 3/2008. PMCID: PMC2613823.
3. Vardy J, Wefel JS, Ahles T, Tannock IF, Schagen SB. Cancer and cancer-therapy related cognitive dysfunction: an international perspective from the Venice cognitive workshop. Ann Oncol 19(4):623-629, 4/2008. e-Pub 10/2007. PMID: 17974553.
4. Mittendorf EA, Wefel JS, Meyers CA, Shapiro SE, Doherty DB, Lee JE, Evans DB, Perrier ND. Improvement of sleep disturbance and neurocognitive function after parathyroidectomy in patients with primary hyperparathyroidism. Endocr Pract 13(4):338-44, Jul-Aug, 7/2007. PMID: 17669708.
5. Chang EL, Wefel JS, Maor MH, Hassenbusch SJ, 3rd, Mahajan A, Lang FF, Woo SY, Mathews LA, Allen PK, Shiu AS, Meyers CA. A pilot study of neurocognitive function in patients with one to three new brain metastases initially treated with stereotactic radiosurgery alone. Neurosurgery 60(2):277-83; discussion 283-4, 2/2007. PMID: 17290178.
6. Wefel JS, Lenzi R, Theriault R, Buzdar AU, Cruickshank S, Meyers CA. 'Chemobrain' in breast carcinoma?: a prologue. Cancer 101(3):466-75, 8/2004. PMID: 15274059.
7. Wefel JS, Lenzi R, Theriault RL, Davis RN, Meyers CA. The cognitive sequelae of standard-dose adjuvant chemotherapy in women with breast carcinoma: results of a prospective, randomized, longitudinal trial. Cancer 100(11):2292-9, 6/2004. PMID: 15160331.
8. Atchison TA, Sanders A, Struchen M, Roebuck T, Wefel JS, High W, Contant C. Relationship between neuropsychological test performance and productivity at 1-year following traumatic brain injury. Clin Neuropsychol 18(2):249-265, 2004. PMID: 15587672.

Invited Articles

1. Dietrich J, Monje M, Wefel J, Meyers C. Clinical patterns and biological correlates of cognitive dysfunction associated with cancer therapy. Oncologist 13(12):1285-1295, 2008. e-Pub 11/19/2008. PMID: 19019972.
2. Wefel JS, Witgert ME, Meyers CA. Neuropsychological sequelae of cancer and cancer therapy. Neuropsychology Review 18(2):121-31, 2008. PMID: 18415683.
3. Kayl AE, Wefel JS, Meyers CA. Chemotherapy and cognition: effects, potential mechanisms, and management. Am J Ther 13(4):362-9, Jul-Aug, 7/2006. PMID: 16858172.
4. Wefel JS, Kayl AE, Meyers CA. Neuropsychological dysfunction associated with cancer and cancer therapies: a conceptual review of an emerging target. Br J Cancer 90(9):1691-6, 5/2004. PMID: 15150608.

Editorials

1. Wefel JS Meyers CA. Cancer as a risk factor for dementia: a house built on shifting sand. J Natl Cancer Inst 97(11):788-9, 6/2005. PMID: 15928294.
2. Meyers CA, Wefel JS. The use of the mini-mental state examination to assess cognitive functioning in cancer trials: no ifs, ands, buts, or sensitivity. J Clin Oncol 21:3557-8, 10/2003. PMID: 12913103.

Grant & Contract Support

Title: SPORE in Brain Cancer Project 4: Genetic modulation of cognitive function and outcomes in glioblastoma patients
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: WKA Yung
Duration: 3/1/2008 - 2/28/2013

Last updated: 9/2/2009