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Jennifer A. Minnix, Ph.D.

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Behavioral Science, Division of OVP, Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX

Bio Statement

I am particularly interested in furthering the understanding of the affective processes of nicotine addiction and I believe that the psychophysiological study of individual differences resulting from and/or leading to chronic nicotine use offers a promising line of inquiry. Moreover, this line of research can be integrated into future treatment strategies that may be able to target individual differences in smokers attempting to quit. I am also interested in developing a multidisciplinary approach to the study of cigarette smoking, including expanding my knowledge of neuro-imaging and co-morbid mood disorders in a smoking population. My expertise in psychophysiology in general and my interest in becoming an expert in neurobiological indices of high-level cognitive and affective processing in particular will provide a unique addition and potential for collaboration in our department’s Tobacco Research and Treatment Program. I worked closely with a variety of mentors to increase my breadth and depth of knowledge related to nicotine dependence, cognitive and affective neuroscience, EEG and fMRI technology, and project administration through my awarded R-25 and K99 training grants. As an independent researcher funded by an R00 grant, I also mentor graduate students and post-docs in clinical research areas related to behavioral therapy for nicotine dependence as well as psychophysiological research design, methodology, and implementation. It would be a pleasure to have the opportunity to mentor students from the R25E training program.

Research Interests

Dr. Minnix is a clinical psychologist who originally joined the Department of Behavioral Science at M. D. Anderson as a post-doctoral fellow in 2005. Her current research focuses primarily on understanding the neurobehavioral mechanisms of nicotine dependence through the psychophysiological study of affective and attentional processes in smokers. She is also interested in developing a multidisciplinary approach to the study of cigarette smoking, including neuroimaging, affect regulation, and co-morbid psychiatric disorders in a smoking population. She is currently the Principal Investigator on a mentored K99/R00 Career Development Award entitled (R00-DA025181-03) “Suppression of negative affect indexed by the late positive potential in smokers attempting to quit,” which investigates the relationship between smoking deprivation and cognitive reappraisal of emotional stimuli. As a postdoctoral fellow, Dr. Minnix received an UTMDACC Education Program in Cancer Prevention Postdoctoral Fellowship Grant (R25CA57730). This grant was entitled, “Affective modulation of negative affect in response to nicotine administration” and evaluated the hypotheses that stress would potentiate emotional reactivity (indexed by the startle probe) to negative affective cues and that nicotine would suppress responses to negative affective cues. Dr. Minnix was also awarded the National Institute of Health’s (NIH) Clinical Research Loan Repayment Award (2006-2008). Dr. Minnix received her Ph.D. in Clinical Psychology from Florida State University in 2005 and completed her clinical internship at Baylor College of Medicine in Houston, Texas.

Education & Training

Degree-Granting Education

2005 Florida State University, Tallahassee, FL, PHD, Clinical Psychology
2002 Florida State University, Tallahassee, FL, MS, Clinical Psychology
2000 The University of Texas, Austin, Austin, TX, BA, Psychology

Postgraduate Training

7/2005-8/2008 Postdoctoral Fellowship, Department of Behavioral Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, Dr. Paul M. Cinciripini
6/2004-6/2005 Clinical Internship, Psychology, Baylor College of Medicine, Houston, TN

Experience/Service

Academic Appointments

Instructor, Department of Behavioral Science, Division of OVP, Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/2008-5/2010

Honors and Awards

2002 Student Research Award, American Psychological Society
2002 Student Research Award, Society for Psychophysiological Research
2000 College Teaching Fellowship, Florida State University
1997-2000 Golden Key Honor Society, The University of Texas
1996-2000 National Dean's List, The University of Texas

Selected Publications

Peer-Reviewed Original Research Articles

1. Versace F, Lam CY, Engelmann JM, Robinson JD, Minnix JA, Brown VL, Cinciripini PM. Beyond cue reactivity: Blunted brain responses to pleasant stimuli predict long-term smoking abstinence. Addict Biol 17(6):991-1000, 11/2012. e-Pub 10/4/2011. PMCID: PMC3252422.
2. Lam CY, Robinson JD, Versace F, Minnix JA, Cui Y, Carter BL, Wetter DW, Cinciripini PM. Affective reactivity during smoking cessation of never-quitters as compared with that of abstainers, relapsers, and continuing smokers. Exp Clin Psychopharmacol 20(2):139-150, 4/2012. e-Pub 10/31/2011. PMCID: PMC3381955.
3. Engelmann JM, Versace F, Robinson JD, Minnix JA, Lam CY, Cui Y, Brown VL, Cinciripini PM. Neural substrates of smoking cue reactivity: A meta-analysis of fMRI studies. Neuroimage 60(1). e-Pub 12/21/2011. PMID: 22206965.
4. Versace F, Engelmann JM, Jackson EF, Costa VD, Robinson JD, Lam CY, Minnix JA, Brown VL, Wetter DW, Cinciripini PM. Do brain responses to emotional images and cigarette cues differ? An fMRI study in smokers. Eur J Neurosci 34(12):2054-63, 12/2011. e-Pub 11/20/2011. PMCID: PMC3237919.
5. Blalock JA, Nayak N, Wetter DW, Schreindorfer L, Minnix JA, Canul J, Cinciripini PM. The relationship of childhood trauma to nicotine dependence in pregnant smokers. Psychol Addict Behav 25(4):652-63, 12/2011. e-Pub 9/2011. PMID: 21928869.
6. Minnix JA, Blalock JA, Marani S, Prokhorov AV, Cinciripini PM. Self-efficacy mediates the effect of depression on smoking susceptibility in adolescents. Nicotine Tob Res 13(8):699-705, 8/2011. e-Pub 4/11/2011. PMCID: PMC3150689.
7. Versace F, Minnix JA, Robinson JD, Lam CY, Brown VL, Cinciripini PM. Brain reactivity to emotional, neutral, and cigarette-related stimuli in smokers. Addict Biol 16(2):296-307, 4/2011. e-Pub 12/23/2010. PMCID: PMC3058803.
8. Blalock JA, Cinciripini PM, Gritz ER, Karam-Hage MA, Lam CY, Minnix JA, Robinson JD. The effect of mood, anxiety and alcohol use disorders on smoking cessation in cancer patients. Journal Cognitive Psychotherapy 25(1):82-96, 3/2011.
9. Blalock JA, Nayak N, Wetter DW, Schreindorfer L, Minnix JA, Canul J, Cinciripini PM. The relationship of childhood trauma to nicotine dependence in pregnant smokers. Psychology of Addictive Behavior, 3/2011.
10. Robinson JD, Lam CY, Carter BL, Minnix JA, Cui Y, Versace F, Wetter DW, Cinciripini PM. A multimodal approach to assessing the impact of nicotine dependence, nicotine abstinence, and craving on negative affect in smokers. Exp Clin Psychopharmacol 19(1):40-52, 2/2011. PMID: 21341922.
11. Minnix JA, Robinson JD, Lam CY, Carter BL, Foreman JE, Vandenbergh DJ, Tomlinson GE, Wetter DW, Cinciripini PM. The Serotonin Transporter Gene and Startle Response During Nicotine Deprivation. Biol Psychol 86(1):1-8, 1/2011. e-Pub 10/1/2010. PMID: 20888887.
12. Versace F, Robinson JD, Lam CY, Minnix JA, Brown VL, Carter BL, Wetter DW, Cinciripini PM. Cigarette cues capture smokers' attention: evidence from event-related potentials. Psychophysiology 47(3):435-41, 5/1/2010. e-Pub 1/11/2010. PMID: 20070579.
13. Cinciripini PM, Blalock JA, Minnix JA, Robinson JD, Brown VL, Lam C, Wetter DW, Schreindorfer L, McCullough JP, Dolan-Mullen P, Stotts AL, Karam-Hage M. Effects of an intensive depression-focused intervention for smoking cessation in pregnancy. J Consult Clin Psychol 78(1):44-54, 2/2010. PMCID: PMC2881321.
14. Lam CY, Robinson JD, Carter BL, Wetter DW, Minnix JA, Cinciripini PM. Nicotine differentially inhibits the acoustic startle reflex in African American and Caucasian American smokers. Addict Behav 33(12):1521-8, 12/2008. e-Pub 7/23/2008. PMCID: PMC2612003.
15. Minnix JA, Romero C, Joiner TE, Weinberg EF. Change in "resolved plans" and "suicidal ideation" factors of suicidality after participation in an intensive outpatient treatment program. J Affect Disord 103(1-3):63-8, 11/2007. e-Pub 3/6/2007. PMID: 17341431.
16. Robinson JD, Lam CY, Minnix JA, Wetter DW, Tomlinson GE, Minna JD, Chen TT, Cinciripini PM. The DRD2 TaqI-B polymorphism and its relationship to smoking abstinence and withdrawal symptoms. Pharmacogenomics J 7(4):266-74, 8/2007. e-Pub 12/26/2006. PMID: 17189962.
17. Lam CY, Minnix JA, Robinson JD, Cinciripini PM. A brief review of pharmacotherapies for smoking cessation. J Natl Compr Canc Netw 4(6):583-9, 7/2006. PMID: 16813725.
18. Blackhart GC, Minnix JA, Kline JP. Can EEG asymmetry patterns predict future development of anxiety and depression? A preliminary study. Biol Psychol 72(1):46-50, 4/2006. e-Pub 10/11/2005. PMID: 16223557.
19. Wingate LR, Bobadilla L, Burns AB, Cukrowicz K, Hernandez A, Ketterman R, Minnix J, Petty S, Richey J, Sachs-Ericsson N, Stanley S, Williams FM, Joiner TE. Suicidality in African American men: The roles of southern residence, religiosity, and social support. Suicide and Life-Threatening Behaviors 35(6):615-629, 2005.
20. Minnix JA, Reitzel LR, Repper KA, Burns AB, Williams FM, Lima E, Cukrowicz KC, Kirsch L, Joiner TE. Total number of clinical scale elevations on the MMPI-II predicts premature termination after controlling for intake severity and personality disorder diagnosis. Personality and Individual Differences 38:1745-1755, 2005.

Grant & Contract Support

Title: Suppression of negative affect indexed by the late positive potential in smokers attempting to quit
Funding Source: NIH/NIDA
Role: Principal Investigator
Duration: 5/1/2011 - 4/30/2014
 
Title: Preliminary effectiveness and safety of bupropion to promote smoking cessation during pregnancy
Funding Source: Center for Clinical and Translational Sciences (CCTS)
Role: Co-Investigator
Principal Investigator: Stotts, AL & Cinciripini, PM
Duration: 9/1/2009 - 8/31/2011
 
Title: Effectiveness of varenicline plus bupropion for smoking cessation
Funding Source: NIH/NIDA
Role: Collaborator
Principal Investigator: Cinciripini, PM
Duration: 7/1/2009 - 6/30/2013
 
Title: Suppression of negative affect indexed by the late positive potential in smokers
Funding Source: NIH/NIDA
Role: Principal Investigator
Duration: 5/1/2009 - 4/30/2011
 
Title: Pharmacogenetics, emotional reactivity and smoking
Funding Source: NIH/NIDA
Role: Collaborator
Principal Investigator: Cinciripini, PM
Duration: 7/15/2004 - 4/30/2012

Last updated: 3/7/2013