Jian Gu, Ph.D.

Peer-Reviewed Articles

1. Yueh TC, Wang YC, Chin YT, Hung YC, Mong MC, Yang YC, Pei JS, Gu J, Tsai CW, Bau DT, Chang WS. Impact of Mir196a-2 Genotypes on Colorectal Cancer Risk in Taiwan. Int J Mol Sci 24(14), 2023. e-Pub 2023. PMID: 37511371.
2. Tsai CW, Shih LC, Chang WS, Hsu CL, He JL, Hsia TC, Wang YC, Gu J, Bau DT. Non-Homologous End-Joining Pathway Genotypes Significantly Associated with Nasopharyngeal Carcinoma Susceptibility. Biomedicines 11(6), 2023. e-Pub 2023. PMID: 37371742.
3. Wang BR, Chang WS, Liao CH, Wang YC, Gu J, Bau DT, Tsai CW. Impacts of Mir146a Genotypes on Bladder Cancer Risk in Taiwan. Biomedicines 11(5), 2023. e-Pub 2023. PMID: 37239070.
4. Bau DT, Liu TY, Tsai CW, Chang WS, Gu J, Yang JS, Shih LC, Tsai FJ. A Genome-Wide Association Study Identified Novel Genetic Susceptibility Loci for Oral Cancer in Taiwan. Int J Mol Sci 24(3), 2023. e-Pub 2023. PMID: 36769103.
5. Xu Y, Wang Z, Wei P, Gairola R, Kelsey KT, Sikora AG, Li G, Gu J. Hypermethylation of nc886 in HPV-positive oropharyngeal cancer and its clinical implications: An epigenome-wide association study. Mol Ther Nucleic Acids 30:596-605, 2022. e-Pub 2022. PMID: 36514351.
6. Berndt SI, Vijai J, Benavente Y, Camp NJ, Nieters A, Wang Z, Smedby KE, Kleinstern G, Hjalgrim H, Besson C, Skibola CF, Morton LM, Brooks-Wilson AR, Teras LR, Breeze C, Arias J, Adami HO, Albanes D, Anderson KC, Ansell SM, Bassig B, Becker N, Bhatti P, Birmann BM, Boffetta P, Bracci PM, Brennan P, Brown EE, Burdett L, Cannon-Albright LA, Chang ET, Chiu BCH, Chung CC, Clavel J, Cocco P, Colditz G, Conde L, Conti DV, Cox DG, Curtin K, Casabonne D, De Vivo I, Diver WR, Dogan A, Edlund CK, Foretova L, Fraumeni JF, Gabbas A, Ghesquières H, Giles GG, Glaser S, Glenn M, Glimelius B, Gu J, Habermann TM, Haiman CA, Haioun C, Hofmann JN, Holford TR, Holly EA, Hutchinson A, Izhar A, Jackson RD, Jarrett RF, Kaaks R, Kane E, Kolonel LN, Kong Y, Kraft P, Kricker A, Lake A, Lan Q, Lawrence C, Li D, Liebow M, Link BK, Magnani C, Maynadie M, McKay J, Melbye M, Miligi L, Milne RL, Molina TJ, Monnereau A, Montalvan R, North KE, Novak AJ, Onel K, Purdue MP, Rand KA, Riboli E, Riby J, Roman E, Salles G, Sborov DW, Severson RK, Shanafelt TD, Smith MT, Smith A, Song KW, Song L, Southey MC, Spinelli JJ, Staines A, Stephens D, Sutherland HJ, Tkachuk K, Thompson CA, Tilly H, Tinker LF, Travis RC, Turner J, Vachon CM, Vajdic CM, Van Den Berg A, Van Den Berg DJ, Vermeulen RCH, Vineis P, Wang SS, Weiderpass E, Weiner GJ, Weinstein S, Doo NW, Ye Y, Yeager M, Yu K, Zeleniuch-Jacquotte A, Zhang Y, Zheng T, Ziv E, Sampson J, Chatterjee N, Offit K, Cozen W, Wu X, Cerhan JR, Chanock SJ, Slager SL, Rothman N. Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes. Leukemia. e-Pub 2022. PMID: 36273105.
7. Wang SC, Tsai CW, Chang WS, Hsia NY, Mong MC, Wang YC, Hsia TC, Gu J, Bau DT. Genetic variants in miR-145 gene are associated with the risk of asthma in Taiwan. Sci Rep 12(1):15155, 2022. e-Pub 2022. PMID: 36071121.
8. Viereckl MJ, Krutsinger K, Apawu A, Gu J, Cardona B, Barratt D, Han Y. Cannabidiol and Cannabigerol Inhibit Cholangiocarcinoma Growth In Vitro via Divergent Cell Death Pathways. Biomolecules 12(6), 2022. e-Pub 2022. PMID: 35740979.
9. Yu Y, Chang K, Chen JS, Bohlender RJ, Fowler J, Zhang D, Huang M, Chang P, Li Y, Wong J, Wang H, Gu J, Wu X, Schildkraut J, Cannon-Albright L, Ye Y, Zhao H, Hildebrandt MAT, Permuth JB, Li D, Scheet P, Huff CD. A whole-exome case-control association study to characterize the contribution of rare coding variation to pancreatic cancer risk. HGG Adv 3(1):100078, 2022. e-Pub 2021. PMID: 35047863.
10. Tsai CW, Chang WS, Xu Y, Huang M, Tamboli P, Wood CG, Bau DT, Gu J. Prognostic significance of circulating insulin growth-like factor 1 and insulin growth-like factor binding protein 3 in renal cell carcinoma patients. Am J Cancer Res 12(2):852-860, 2022. e-Pub 2022. PMID: 35261807.
11. Xu Y, Tsai CW, Chang WS, Han Y, Huang M, Pettaway CA, Bau DT, Gu J. Epigenome-Wide Association Study of Prostate Cancer in African Americans Identifies DNA Methylation Biomarkers for Aggressive Disease. Biomolecules 11(12), 2021. e-Pub 2021. PMID: 34944472.
12. Tsai CW, Chang WS, Xu Y, Huang M, Bau DT, Gu J. Associations of genetically predicted circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 with bladder cancer risk. Mol Carcinog 60(11):726-733, 2021. e-Pub 2021. PMID: 34293213.
13. Chen M, Tsai CW, Chang WS, Xiong GY, Xu Y, Bau DT, Gu J. High circulating insulin-like growth factor-1 reduces the risk of renal cell carcinoma: a Mendelian randomization study. Carcinogenesis 42(6):826-830, 2021. e-Pub 2021. PMID: 33852723.
14. Chong W, Zhang Z, Luo R, Gu J, Lin J, Wei Q, Li B, Myers R, Lu-Yao G, Kelly WK, Wang C, Yang H. Integration of circulating tumor cell and neutrophil-lymphocyte ratio to identify high-risk metastatic castration-resistant prostate cancer patients. BMC Cancer 21(1):655, 2021. e-Pub 2021. PMID: 34078304.
15. Chen M, Xu Y, Xu J, Chancoco H, Gu J. Leukocyte telomere length and bladder cancer risk: a large case control study and Mendelian randomization analysis. Cancer Epidemiol Biomarkers Prev 30(1):203-209, 2021. e-Pub 2020. PMID: 32998948.
16. Wang C, Zhang Z, Chong W, Luo R, Myers RE, Gu J, Lin J, Wei Q, Li B, Rebbeck TR, Lu-Yao G, Kelly WK, Yang H. Improved Prognostic Stratification Using Circulating Tumor Cell Clusters in Patients with Metastatic Castration-Resistant Prostate Cancer. Cancers (Basel) 13(2), 2021. e-Pub 2021. PMID: 33450815.
17. Han Y, Zhang M, Xu J, Li J, Xu Y, Thompson TC, Logothetis CJ, Sun D, Gu J. Genome-wide DNA methylation profiling of leukocytes identifies CpG methylation signatures of aggressive prostate cancer. Am J Cancer Res 11(3):968-978, 2021. e-Pub 2021. PMID: 33791167.
18. Xu Y, Tsai CW, Chang WS, Xiong GY, Huang M, Torres KE, Bau DT, Gu J. Genetically predicted high circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 increase the risks of soft tissue sarcoma. Am J Cancer Res 11(8):3980-3989, 2021. e-Pub 2021. PMID: 34522462.
19. Tsai CW, Chang WS, Xu J, Xu Y, Huang M, Pettaway C, Bau DT, Gu J. Leukocyte telomere length is associated with aggressive prostate cancer in localized African American prostate cancer patients. Carcinogenesis 41(9):1213-1218, 2020. PMID: 32614411.
20. Deng Y, Xie K, Logothetis CJ, Thompson TC, Kim J, Huang M, Chang DW, Gu J, Wu X, Ye Y. Genetic Variants in Epithelial Mesenchymal Transition Genes as Predictors of Clinical Outcomes in Localized Prostate Cancer. Carcinogenesis 41(8):1057-1064, 2020. e-Pub 2020. PMID: 32215555.
21. Xu J, Chang WS, Tsai CW, Bau DT, Davis JW, Thompson TC, Logothetis CJ, Gu J. Mitochondrial DNA copy number in peripheral blood leukocytes is associated with biochemical recurrence in prostate cancer patients in African Americans. Carcinogenesis 41(3):267-273, 2020. e-Pub 2019. PMID: 31408512.
22. Xu Y, Xu J, Chancoco H, Huang M, Torres KE, Gu J. Long Leukocyte Telomere Length Is Associated with Increased Risks of Soft Tissue Sarcoma: A Mendelian Randomization Study. Cancers (Basel) 12(3), 2020. e-Pub 2020. PMID: 32150919.
23. Deng Y, Zhu J, Liu Z, Huang M, Chang DW, Gu J. Elevated systemic inflammatory responses, factors associated with physical and mental quality of life, and prognosis of hepatocellular carcinoma. Aging (Albany NY) 12(5):4357-4370, 2020. e-Pub 2020. PMID: 32145060.
24. Xu J, Chang WS, Tsai CW, Bau DT, Xu Y, Davis JW, Thompson TC, Logothetis CJ, Gu J. Leukocyte telomere length is associated with aggressive prostate cancer in localized prostate cancer patients. EBioMedicine 52:102616, 2020. e-Pub 2020. PMID: 31981976.
25. Wang R, Song S, Harada K, Ghazanfari Amlashi F, Badgwell B, Pizzi MP, Xu Y, Zhao W, Dong X, Jin J, Wang Y, Scott A, Ma L, Huo L, Vicente D, Blum Murphy M, Shanbhag N, Tatlonghari G, Thomas I, Rogers J, Kobayashi M, Vykoukal J, Estrella JS, Roy-Chowdhuri S, Han G, Zhang S, Mao X, Song X, Zhang J, Gu J, Johnson RL, Calin GA, Peng G, Lee JS, Hanash SM, Futreal A, Wang Z, Wang L, Ajani JA.. Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response. Gut 69(1):18-31, 2020. e-Pub 2019. PMID: 31171626.
26. Chen M, Tsai CW, Chang WS, Xu J, Xu Y, Bau DT, Gu J. Prognostic value of leukocyte telomere length in renal cell carcinoma patients. Am J Cancer Res 10(10):3428-3439, 2020. e-Pub 2020. PMID: 33163281.
27. Shen TC, Tsai CW, Chang WS, Wang YC, Hsu HM, Li HT, Gu J, Bau DT. Genetic Variants in the Nucleotide Excision Repair Genes are Associated with the Risk of Developing Endometriosis. Biol Reprod 101(5):928-937, 2019. e-Pub 2019. PMID: 31373346.
28. Xu J, Tsai CW, Chang WS, Han Y, Bau DT, Pettaway CA, Gu J. Methylation of global DNA repeat LINE-1 and subtelomeric DNA repeats D4Z4 in leukocytes is associated with biochemical recurrence in African American prostate cancer patients. Carcinogenesis. e-Pub 2019. PMID: 30874286.
29. Zhou W, Machiela MJ, Freedman ND, Rothman N, Malats N, Dagnall C, Caporaso N, Teras LT, Gaudet MM, Gapstur SM, Stevens VL, Jacobs KB, Sampson J, Albanes D, Weinstein S, Virtamo J, Berndt S, Hoover RN, Black A, Silverman D, Figueroa J, Garcia-Closas M, Real FX, Earl J, Marenne G, Rodriguez-Santiago B, Karagas M, Johnson A, Schwenn M, Wu X, Gu J, Ye Y, Hutchinson A, Tucker M, Perez-Jurado LA, Dean M, Yeager M, Chanock SJ. Reply to 'Mosaic loss of chromosome Y in leukocytes matters'. Nat Genet 51(1):7-9, 2019. PMID: 30514911.
30. Wang Q, Gregg JR, Gu J, Ye Y, Chang DW, Davis JW, Thompson TC, Kim J, Logothetis CJ, Wu X. Genetic associations of T cell cancer immune response with tumor aggressiveness in localized prostate cancer patients and disease reclassification in an active surveillance cohort. Oncoimmunology 8(1):e1483303, 2019. e-Pub 2018. PMID: 30546938.
31. Lin SH, Raju GS, Huff C, Ye Y, Gu J, Chen JS, Hildebrandt MAT, Liang H, Menter DG, Morris J, Hawk E, Stroehlein JR, Futreal A, Kopetz S, Mishra L, Wu X. The somatic mutation landscape of premalignant colorectal adenoma. Gut 67(7):1299-1305, 2018. e-Pub 2017. PMID: 28607096.
32. Zhang L, Lin J, Ye Y, Oba T, Gentile E, Lian J, Wang J, Zhao Y, Gu J, Wistuba II, Roth JA, Ji L, Wu X. Serum MicroRNA-150 Predicts Prognosis for Early-Stage Non-Small Cell Lung Cancer and Promotes Tumor Cell Proliferation by Targeting Tumor Suppressor Gene SRCIN1. Clin Pharmacol Ther 103(6):1061-1073, 2018. e-Pub 2017. PMID: 28891208.
33. Shu X, Gu J, Huang M, Tannir NM, Matin SF, Karam JA, Wood CG, Wu X, Ye Y. Germline genetic variants in somatically significantly mutated genes in tumors are associated with renal cell carcinoma risk and outcome. Carcinogenesis 39(6):752-757, 2018. PMID: 29635281.
34. Han Y, Xu J, Kim J, Wu X, Gu J. LINE-1 methylation in peripheral blood leukocytes and clinical characteristics and prognosis of prostate cancer patients. Oncotarget 8(55):94020-94027, 2017. e-Pub 2017. PMID: 29212206.
35. Zhao H, Han L, Chang D, Ye Y, Shen J, Daniel CR, Gu J, Chow WH, Wu X. Social-demographics, health behaviors, and telomere length in the Mexican American Mano a Mano Cohort. Oncotarget 8(57):96553-96567, 2017. e-Pub 2017. PMID: 29228552.
36. Xie K, Ye Y, Zeng Y, Gu J, Yang H, Wu X. Polymorphisms in genes related to epithelial-mesenchymal transition and risk of non-small cell lung cancer. Carcinogenesis 38(10):1029-1035, 2017. PMID: 28968839.
37. Xiao ZD, Han L, Lee H, Zhuang L, Zhang Y, Baddour J, Nagrath D, Wood CG, Gu J, Wu X, Liang H, Gan B. Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development. Nat Commun 8(1):783, 2017. e-Pub 2017. PMID: 28978906.
38. Mendoza-Pérez J, Gu J, Herrera LA, Tannir NM, Zhang S, Matin S, Karam JA, Wood CG, Wu X. Prognostic significance of promoter CpG island methylation of obesity-related genes in patients with nonmetastatic renal cell carcinoma. Cancer 123(18):3617-3627, 2017. e-Pub 2017. PMID: 28543182.
39. Han Y, Xu J, Kim J, Wu X, Gu J. Methylation of subtelomeric repeat D4Z4 in peripheral blood leukocytes is associated with biochemical recurrence in localized prostate cancer patients. Carcinogenesis 38(8):821-826, 2017. PMID: 28854562.
40. Lin J, Zandi R, Shao R, Gu J, Ye Y, Wang J, Zhao Y, Pertsemlidis A, Wistuba II, Wu X, Roth JA, Ji L. A miR-SNP biomarker linked to an increased lung cancer survival by miRNA-mediated down-regulation of FZD4 expression and Wnt signaling. Sci Rep 7(1):9029, 2017. e-Pub 2017. PMID: 28831115.
41. Li R, Gu J, Heymach JV, Shu X, Zhao L, Han B, Ye Y, Roth J, Wu X.. Hypoxia pathway genetic variants predict survival of non-small-cell lung cancer patients receifving platinum-based chemotherapy. Carcinogenesis 38(4):419-424, 2017.
42. Sun Y, Tao W, Huang M, Wu X, Gu J. Genetic variants in telomere-maintenance genes are associated with ovarian cancer risk and outcome. J Cell Mol Med 21(3):510-518, 2017. e-Pub 2016. PMID: 28233473.
43. Tu H, Gu J, Meng QH, Kim J, Strom S, Davis JW, He Y, Wagar EA, Thompson TC, Logothetis CJ, Wu X. Low serum testosterone is associated with tumor aggressiveness and poor prognosis in prostate cancer. Oncol Lett 13(3):1949-1957, 2017. e-Pub 2017. PMID: 28454349.
44. Qu K, Gu J, Ye Y, Williams SB, Dinney CP, Wu X, Kamat A. High baseline levels of interleukin-8 in leukocytes and urine predict tumor recurrence in non-muscle invasive bladder cancer patients receiving bacillus Calmette-Guerin therapy: A long-term survival analysis. Oncoimmunology 6(2):e1265719, 2017. e-Pub 2017. PMID: 28344874.
45. Shu X, Hildebrandt MA, Gu J, Tannir NM, Matin SF, Karam JA, Wood CG, Wu X. MicroRNA profiling in clear cell renal cell carcinoma tissues potentially links tumorigenesis and recurrence with obesity. Br J Cancer 116(1):77-84, 2017. e-Pub 2016. PMID: 27907930.
46. Wu X, Wen CP, Ye Y, Tsai M, Wen C, Roth JA, Pu X, Chow WH, Huff C, Cunningham S, Huang M, Wu S, Tsao CK, Gu J, Lippman SM. Personalized Risk Assessment in Never, Light, and Heavy Smokers in a prospective cohort in Taiwan. Sci Rep 6:36482, 2016. e-Pub 2016. PMID: 27805040.
47. Shu X, Ye Y, Gu J, He Y, Davis JW, Thompson TC, Logothetis CJ, Kim J, Wu X. Genetic variants of the Wnt signaling pathway as predictors of aggressive disease and reclassification in men with early stage prostate cancer on active surveillance. Carcinogenesis 37(10):965-71, 2016. e-Pub 2016. PMID: 27515962.
48. Xie H, Tao W, Wu X, Gu J. Genetic variations in apoptosis pathway and the risk of ovarian cancer. Oncotarget 7(35):10772, 2016. e-Pub 2016. PMID: 27462919.
49. Chen M, Rothman N, Ye Y, Gu J, Scheet PA, Huang M, Chang DW, Dinney CP, Silverman DT, Figueroa JD, Chanock SJ, Wu X. Pathway analysis of bladder cancer genome-wide association study identifies novel pathways involved in bladder cancer development. Genes Cancer 7(7-8):229-239, 2016. PMID: 27738493.
50. Sun Y, Zhang L, Ho SS, Wu X, Gu J. Lower mitochondrial DNA copy number in peripheral blood leukocytes increases the risk of endometrial cancer. Mol Carcinog 55(6):1111-7, 2016. e-Pub 2015. PMID: 26258624.
51. Wu X, Hildebrandt MA, Ye Y, Chow WH, Gu J, Cunningham S, Zhao H, Hawk ET, Wagar E, Rodriguez A, Hamilton SR. Cohort Profile: The MD Anderson Cancer Patients and Survivors Cohort (MDA-CPSC). Int J Epidemiol 45(3):713-713f, 2016. e-Pub 2015. PMID: 26686840.
52. Zhou W, Machiela MJ, Freedman ND, Rothman N, Malats N, Dagnall C, Caporaso N, Teras LT, Gaudet MM, Gapstur SM, Stevens VL, Jacobs KB, Sampson J, Albanes D, Weinstein S, Virtamo J, Berndt S, Hoover RN, Black A, Silverman D, Figueroa J, Garcia-Closas M, Real FX, Earl J, Marenne G, Rodriguez-Santiago B, Karagas M, Johnson A, Schwenn M, Wu X, Gu J, Ye Y, Hutchinson A, Tucker M, Perez-Jurado LA, Dean M, Yeager M, Chanock SJ. Mosaic loss of chromosome Y is associated with common variation near TCL1A. Nat Genet 48(5):563-8, 2016. e-Pub 2016. PMID: 27064253.
53. Mendoza-Pérez J, Gu J, Herrera LA, Tannir NM, Matin SF, Karam JA, Huang M, Chang DW, Wood CG, Wu X. Genomic DNA hypomethylation and risk of renal cell carcinoma: A case-control study. Clin Cancer Res 22(8):2074-82, 2016. e-Pub 2015. PMID: 26655847.
54. Machiela MJ, Lan Q, Slager SL, Vermeulen RC, Teras LR, Camp NJ, Cerhan JR, Spinelli JJ, Wang SS, Nieters A, Vijai J, Yeager M, Wang Z, Ghesquières H, McKay J, Conde L, de Bakker PI, Cox DG, Burdett L, Monnereau A, Flowers CR, De Roos AJ, Brooks-Wilson AR, Giles GG, Melbye M, Gu J, Jackson RD, Kane E, Purdue MP, Vajdic CM, Albanes D, Kelly RS, Zucca M, Bertrand KA, Zeleniuch-Jacquotte A, Lawrence C, Hutchinson A, Zhi D, Habermann TM, Link BK, Novak AJ, Dogan A, Asmann YW, Liebow M, Thompson CA, Ansell SM, Witzig TE, Tilly H, Haioun C, Molina TJ, Hjalgrim H, Glimelius B, Adami HO, Roos G, Bracci PM, Riby J, Smith MT, Holly EA, Cozen W, Hartge P, Morton LM, Severson RK, Tinker LF, North KE, Becker N, Benavente Y, Boffetta P, Brennan P, Foretova L, Maynadie M, Staines A, Lightfoot T, Crouch S, Smith A, Roman E, Diver WR, Offit K, Zelenetz A, Klein RJ, Villano DJ, Zheng T, Zhang Y, Holford TR, Turner J, Southey MC, Clavel J, Virtamo J, Weinstein S, Riboli E, Vineis P, Kaaks R, Boeing H, Tjønneland A, Angelucci E, Di Lollo S, Rais M, De Vivo I, Giovannucci E, Kraft P, Huang J, Ma B, Ye Y, Chiu BC, Liang L, Park JH, Chung CC, Weisenburger DD, Fraumeni JF, Salles G, Glenn M, Cannon-Albright L, Curtin K, Wu X, Smedby KE, de Sanjose S, Skibola CF, Berndt SI, Birmann BM, Chanock SJ, Rothman N. Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes. Hum Mol Genet 25(8):1663-76, 2016. e-Pub 2016. PMID: 27008888.
55. Berndt SI, Camp NJ, Skibola CF, Vijai J, Wang Z, Gu J, Nieters A, Kelly RS, Smedby KE, Monnereau A, Cozen W, Cox A, Wang SS, Lan Q, Teras LR, Machado M, Yeager M, Brooks-Wilson AR, Hartge P, Purdue MP, Birmann BM, Vajdic CM, Cocco P, Zhang Y, Giles GG, Zeleniuch-Jacquotte A, Lawrence C, Montalvan R, Burdett L, Hutchinson A, Ye Y, Call TG, Shanafelt TD, Novak AJ, Kay NE, Liebow M, Cunningham JM, Allmer C, Hjalgrim H, Adami HO, Melbye M, Glimelius B, Chang ET, Glenn M, Curtin K, Cannon-Albright LA, Diver WR, Link BK, Weiner GJ, Conde L, Bracci PM, Riby J, Arnett DK, Zhi D, Leach JM, Holly EA, Jackson RD, Tinker LF, Benavente Y, Sala N, Casabonne D, Becker N, Boffetta P, Brennan P, Foretova L, Maynadie M, McKay J, Staines A, Chaffee KG, Achenbach SJ, Vachon CM, Goldin LR, Strom SS, Leis JF, Weinberg JB, Caporaso NE, Norman AD, De Roos AJ, Morton LM, Severson RK, Riboli E, Vineis P, Kaaks R, Masala G, Weiderpass E, Chirlaque MD, Vermeulen RC, Travis RC, Southey MC, Milne RL, Albanes D, Virtamo J, Weinstein S, Clavel J, Zheng T, Holford TR, Villano DJ, Maria A, Spinelli JJ, Gascoyne RD, Connors JM, Bertrand KA, Giovannucci E, Kraft P, Kricker A, Turner J, Ennas MG, Ferri GM, Miligi L, Liang L, Ma B, Huang J, Crouch S, Park JH, Chatterjee N, North KE, Snowden JA, Wright J, Fraumeni JF, Offit K, Wu X, de Sanjose S, Cerhan JR, Chanock SJ, Rothman N, Slager SL. Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. Nat Commun 7:10933, 2016. e-Pub 2016. PMID: 26956414.
56. Daniel CR, Shu X, Ye Y, Gu J, Raju GS, Kopetz S, Wu X. Severe obesity prior to diagnosis limits survival in colorectal cancer patients evaluated at a large cancer centre. Br J Cancer 114(1):103-9, 2016. e-Pub 2015. PMID: 26679375.
57. Tu H, Gu J, Meng QH, Kim J, Davis JW, He Y, Wagar EA, Thompson TC, Logothetis CJ, Wu X. Mitochondrial DNA copy number in peripheral blood leukocytes and the aggressiveness of localized prostate cancer. Oncotarget 6(39):41988-96, 2015. PMID: 26515605.
58. Sampson JN, Wheeler WA, Yeager M, Panagiotou O, Wang Z, Berndt SI, Lan Q, Abnet CC, Amundadottir LT, Figueroa JD, Landi MT, Mirabello L, Savage SA, Taylor PR, De Vivo I, McGlynn KA, Purdue MP, Rajaraman P, Adami HO, Ahlbom A, Albanes D, Amary MF, An SJ, Andersson U, Andriole G, Andrulis IL, Angelucci E, Ansell SM, Arici C, Armstrong BK, Arslan AA, Austin MA, Baris D, Barkauskas DA, Bassig BA, Becker N, Benavente Y, Benhamou S, Berg C, Van Den Berg D, Bernstein L, Bertrand KA, Birmann BM, Black A, Boeing H, Boffetta P, Boutron-Ruault MC, Bracci PM, Brinton L, Brooks-Wilson AR, Bueno-de-Mesquita HB, Burdett L, Buring J, Butler MA, Cai Q, Cancel-Tassin G, Canzian F, Carrato A, Carreon T, Carta A, Chan JK, Chang ET, Chang GC, Chang IS, Chang J, Chang-Claude J, Chen CJ, Chen CY, Chen C, Chen CH, Chen C, Chen H, Chen K, Chen KY, Chen KC, Chen Y, Chen YH, Chen YS, Chen YM, Chien LH, Chirlaque MD, Choi JE, Choi YY, Chow WH, Chung CC, Clavel J, Clavel-Chapelon F, Cocco P, Colt JS, Comperat E, Conde L, Connors JM, Conti D, Cortessis VK, Cotterchio M, Cozen W, Crouch S, Crous-Bou M, Cussenot O, Davis FG, Ding T, Diver WR, Dorronsoro M, Dossus L, Duell EJ, Ennas MG, Erickson RL, Feychting M, Flanagan AM, Foretova L, Fraumeni JF, Freedman ND, Beane Freeman LE, Fuchs C, Gago-Dominguez M, Gallinger S, Gao YT, Gapstur SM, Garcia-Closas M, García-Closas R, Gascoyne RD, Gastier-Foster J, Gaudet MM, Gaziano JM, Giffen C, Giles GG, Giovannucci E, Glimelius B, Goggins M, Gokgoz N, Goldstein AM, Gorlick R, Gross M, Grubb R, Gu J, Guan P, Gunter M, Guo H, Habermann TM, Haiman CA, Halai D, Hallmans G, Hassan M, Hattinger C, He Q, He X, Helzlsouer K, Henderson B, Henriksson R, Hjalgrim H, Hoffman-Bolton J, Hohensee C, Holford TR, Holly EA, Hong YC, Hoover RN, Horn-Ross PL, Hosain GM, Hosgood HD, Hsiao CF, Hu N, Hu W, Hu Z, Huang MS, Huerta JM, Hung JY, Hutchinson A, Inskip PD, Jackson RD, Jacobs EJ, Jenab M, Jeon HS, Ji BT, Jin G, Jin L, Johansen C, Johnson A, et al. Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types. J Natl Cancer Inst 107(12):djv279, 2015. e-Pub 2015. PMID: 26464424.
59. Sun Y, Zhang L, Zhao L, Wu X, Gu J. Association of leukocyte telomere length in peripheral blood leukocytes with endometrial cancer risk in Caucasian Americans. Carcinogenesis 36(11):1327-32, 2015. e-Pub 2015. PMID: 26385889.
60. Sanchez-Espiridion B, Liang D, Ajani JA, Liang S, Ye Y, Hildebrandt MA, Gu J, Wu X. Identification of Serum Markers of Esophageal Adenocarcinoma by Global and Targeted Metabolic Profiling. Clin Gastroenterol Hepatol 13(10):1730-1737.e9, 2015. e-Pub 2015. PMID: 25998788.
61. Tan W, Gu J, Huang M, Wu X, Hildebrandt MA. Epigenetic analysis of microRNA genes in tumors from surgically resected lung cancer patients and association with survival. Mol Carcinog 54 Suppl 1:E45-51, 2015. e-Pub 2014. PMID: 24665010.
62. Kim ES, Ye Y, Vaporciyan AA, Xing J, Huang M, Gu J, Roth JA, Lippman SM, Wu X. Telomere length and recurrence risk after curative resection in patients with early-stage non-small cell lung cancer: a prospective cohort study. J Thorac Oncol 10(2):302-8, 2015. e-Pub 2014. PMID: 25299235.
63. Lin J, Blalock JA, Chen M, Ye Y, Gu J, Cohen L, Cinciripini PM, Wu X. Depressive Symptoms and Short Telomere Length Are Associated with Increased Mortality in Bladder Cancer Patients. Cancer Epidemiol Biomarkers Prev 24(2):336-43, 2015. e-Pub 2014. PMID: 25416716.
64. Liu X, Meng QH, Ye Y, Hildebrandt MA, Gu J, Wu X. Prognostic significance of pretreatment serum levels of albumin, LDH and total bilirubin in patients with non-metastatic breast cancer. Carcinogenesis 36(2):243-8, 2015. e-Pub 2014. PMID: 25524924.
65. Melkonian SC, Wang X, Gu J, Matin SF, Tannir NM, Wood CG, Wu X. Mitochondrial DNA copy number in peripheral blood leukocytes and the risk of clear cell renal cell carcinoma. Carcinogenesis 36(2):249-55, 2015. e-Pub 2014. PMID: 25524925.
66. Xie H, Gong Y, Dai J, Wu X, Gu J. Genetic variations in base excision repair pathway and risk of bladder cancer: a case-control study in the United States. Mol Carcinog 50(1):50-7, 2015. e-Pub 2013. PMID: 24038406.
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121. Chen M, Cassidy A, Gu J, Delclos GL, Zhen F, Yang H, Hildebrandt MA, Lin J, Ye Y, Chamberlain RM, Dinney CP, Wu X. Genetic variations in PI3K-AKT-mTOR pathway and bladder cancer risk. Carcinogenesis 30(12):2047-52, 2009. PMID: 19875696.
122. Ye Y, Wang KK, Gu J, Yang H, Lin J, Ajani JA, Wu X. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. Cancer Prev Res (Phila) 1(6):460-9, 2008. PMID: 19138993.
123. Xing J, Chen M, Wood CG, Lin J, Spitz MR, Ma J, Amos CI, Shields PG, Benowitz NL, Gu J, de Andrade M, Swan GE, Wu X. Mitochondrial DNA content: its genetic heritability and association with renal cell carcinoma. J Natl Cancer Inst 100(15):1104-12, 2008. e-Pub 2008. PMID: 18664653.
124. Xing J, Stewart DJ, Gu J, Lu C, Spitz MR, Wu X. Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer. Br J Cancer 98(10):1716-22, 2008. e-Pub 2008. PMID: 18414412.
125. Zhu Y, Yang H, Chen Q, Lin J, Grossman HB, Dinney CP, Wu X, Gu J. Modulation of DNA damage/DNA repair capacity by XPC polymorphisms. DNA Repair (Amst) 7(2):141-8, 2008. e-Pub 2007. PMID: 17923445.
126. Yang H, Gu J, Lin X, Grossman HB, Ye Y, Dinney CP, Wu X. Profiling of genetic variations in inflammation pathway genes in relation to bladder cancer predisposition. Clin Cancer Res 14(7):2236-44, 2008. PMID: 18381966.
127. Amos CI, Wu X, Broderick P, Gorlov IP, Gu J, Eisen T, Dong Q, Zhang Q, Gu X, Vijayakrishnan J, Sullivan K, Matakidou A, Wang Y, Mills G, Doheny K, Tsai YY, Chen WV, Shete S, Spitz MR, Houlston RS. Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet 40(5):616-22, 2008. PMID: 18385676.
128. Ye Y, Yang H, Grossman HB, Dinney C, Wu X, Gu J. Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer. Cancer 112(11):2467-74, 2008. PMID: 18361427.
129. Gu J, Horikawa Y, Chen M, Dinney CP, Wu X. Benzo(a)pyrene diol epoxide-induced chromosome 9p21 aberrations are associated with increased risk of bladder cancer. Cancer Epidemiol Biomarkers Prev 17(9):2445-50, 2008. PMID: 18768515.
130. Xing J, Wu X, Vaporciyan AA, Spitz MR, Gu J. Prognostic significance of ataxia-telangiectasia mutated, DNA-dependent protein kinase catalytic subunit, and Ku heterodimeric regulatory complex 86-kD subunit expression in patients with nonsmall cell lung cancer. Cancer 112(12):2756-64, 2008. PMID: 18457328.
131. Wu X, Lu C, Ye Y, Chang J, Yang H, Lin J, Gu J, Hong WK, Stewart D, Spitz MR. Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy. Pharmacogenet Genomics 18(11):955-65, 2008. PMID: 18854777.
132. Horikawa Y, Wood CG, Yang H, Zhao H, Ye Y, Gu J, Lin J, Habuchi T, Wu X. Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma. Clin Cancer Res 14(23):7956-62, 2008. PMID: 19047128.
133. Gu J, Gong Y, Huang M, Lu C, Spitz MR, Wu X. Polymorphisms of STK15 (Aurora-A) gene and lung cancer risk in Caucasians. Carcinogenesis 28(2):350-5, 2007. PMID: 16926177.
134. Chen M, Gu J, Xing J, Spitz MR, Wu X. Irradiation-induced telomerase activity and the risk of lung cancer: a pilot case-control study. Cancer 109(6):1157-63, 2007. PMID: 17265522.
135. Kader AK, Liu J, Shao L, Dinney CP, Lin J, Wang Y, Gu J, Grossman HB, Wu X. Matrix metalloproteinase polymorphisms are associated with bladder cancer invasiveness. Clin Cancer Res 13(9):2614-20, 2007. PMID: 17473191.
136. Engels EA, Wu X, Gu J, Dong Q, Liu J, Spitz M. Systematic evaluation of genetic variants in the inflammation pathway and risk of lung cancer. Cancer Res 67:6520-7, 2007. e-Pub 2007. PMID: 17596594.
137. Milam MR, Gu J, Yang H, Celestino J, Wu W, Horwitz IB, Lacour RA, Westin SN, Gershenson DM, Wu X, Lu KH. STK15 F31I Polymorphism is associated with Increased Uterine Cancer Risk: A Pilot Study. Gynecol Oncol 107(1):71-4, 2007. e-Pub 2007. PMID: 17599395.
138. Wu X, Lin J, Grossman HB, Huang M, Gu J, Etzel CJ, Amos CI, Dinney CP, Spitz MR. Projecting Individualized Probabilities of Developing Bladder Cancer in Caucasians. J Clin Oncol 25(31):4974-81, 2007. e-Pub 2007. PMID: 17971596.
139. Lin J, Swan GE, Shields PG, Benowitz NL, Gu J, Amos CI, de Andrade M, Spitz MR, Wu X. Mutagen sensitivity and genetic variants in nucleotide excision repair pathway: genotype-phenotype correlation. Cancer Epidemiol Biomarkers Prev 16(10):2065-71, 2007. e-Pub 2007. PMID: 17932354.
140. Chen M, Kamat AM, Huang M, Grossman HB, Dinney CP, Lerner SP, Wu X, Gu J. High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder cancer risk. Carcinogenesis 28(10):2160-5, 2007. e-Pub 2007. PMID: 17728339.
141. Saldivar JS, Lu KH, Liang D, Gu J, Huang M, Vlastos AT, Follen M, Wu X. Moving toward individualized therapy based on NER polymorphisms that predict platinum sensitivity in ovarian cancer patients. Gynecol Oncol 107(1 Suppl 1):S223-9, 2007. e-Pub 2007. PMID: 17825393.
142. Schabath MB, Wu X, Wei Q, Li G, Gu J, Spitz MR. Combined effects of the p53 and p73 polymorphisms on lung cancer risk. Cancer Epidemiol Biomarkers Prev 15(1):158-61, 2006. PMID: 16434604.
143. Gu J, Berman D, Lu C, Wistuba II, Roth JA, Frazier M, Spitz MR, Wu X. Aberrant promoter methylation profile and association with survival in patients with non-small cell lung cancer. Clin Cancer Res 12(24):7329-38, 2006. PMID: 17189404.
144. Gu J, Wu X, Dong Q, Romeo MJ, Lin X, Gutkind JS, Berman DM. A nonsynonymous single-nucleotide polymorphism in the PDZ-Rho guanine nucleotide exchange factor (Ser1416Gly) modulates the risk of lung cancer in Mexican Americans. Cancer 106(12):2716-24, 2006. PMID: 16691626.
145. Huang M, Spitz MR, Gu J, Lee JJ, Lin J, Lippman SM, Wu X. Cyclin D1 gene polymorphism as a risk factor for oral premalignant lesions. Carcinogenesis 27(10):2034-7, 2006. e-Pub 2006. PMID: 16638786.
146. Kader AK, Shao L, Dinney CP, Schabath MB, Wang Y, Liu J, Gu J, Grossman HB, Wu X. Matrix metalloproteinase polymorphisms and bladder cancer risk. Cancer Res 66(24):11644-8, 2006. PMID: 17178858.
147. Lin X, Gu J, Lu C, Spitz MR, Wu X. Expression of telomere-associated genes as prognostic markers for overall survival in patients with non-small cell lung cancer. Clin Cancer Res 12(19):5720-5, 2006. PMID: 17020976.
148. Wu X, Gu J, Dong Q, Huang M, Do KA, Hong WK, Spitz MR. Joint effect of mutagen sensitivity and insulin-like growth factors in predicting the risk of developing secondary primary tumors and tumor recurrence in patients with head and neck cancer. Clin Cancer Res 12(23):7194-201, 2006. PMID: 17145846.
149. Wu X, Gu J, Grossman HB, Amos CI, Etzel C, Huang M, Zhang Q, Millikan RE, Lerner S, Dinney CP, Spitz MR. Bladder cancer predisposition: a multigenic approach to DNA-repair and cell-cycle-control genes. Am J Hum Genet 78(3):464-79, 2006. PMID: 16465622.
150. Wu X, Gu J, Wu TT, Swisher SG, Liao Z, Correa AM, Liu J, Etzel CJ, Amos CI, Huang M, Chiang SS, Milas L, Hittelman WN, Ajani JA. Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer. J Clin Oncol 24(23):3789-98, 2006. PMID: 16785472.
151. Wu X, Spitz MR, Amos CI, Lin J, Shao L, Gu J, de Andrade M, Benowitz NL, Shields PG, Swan GE. Mutagen sensitivity has high heritability: evidence from a twin study. Cancer Res 66(12):5993-6, 2006. PMID: 16778168.
152. Gu J, Spitz MR, Zhao H, Lin J, Grossman HB, Dinney CP, Wu X. Roles of tumor suppressor and telomere maintenance genes in cancer and aging--an epidemiological study. Carcinogenesis 26(10):1741-7, 2005. e-Pub 2005. PMID: 15905204.
153. Gu J, Liang D, Wang Y, Lu C, Wu X. Effects of N-acetyl transferase 1 and 2 polymorphisms on bladder cancer risk in Caucasians. Mutat Res 581(1-2):97-104, 2005. PMID: 15725609.
154. Gu J, Zhao H, Dinney CP, Zhu Y, Leibovici D, Bermejo CE, Grossman HB, Wu X. Nucleotide excision repair gene polymorphisms and recurrence after treatment for superficial bladder cancer. Clin Cancer Res 11(4):1408-15, 2005. PMID: 15746040.
155. Leibovici D, Grossman HB, Dinney CP, Millikan RE, Lerner S, Wang Y, Gu J, Dong Q, Wu X. Polymorphisms in inflammation genes and bladder cancer: from initiation to recurrence, progression, and survival. J Clin Oncol 23(24):5746-56, 2005. PMID: 16110031.
156. Gu J, Zhang L, Swisher SG, Liu J, Roth JA, Fang B. Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis. Oncogene 23(6):1300-7, 2004. PMID: 14676844.
157. Wu S, Zhu H, Gu J, Zhang L, Teraishi F, Davis JJ, Jacob DA, Fang B. Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy)propyl]amino]ethanol. Cancer Res 64(3):1110-3, 2004. PMID: 14871845.
158. Huang X, Lin T, Gu J, Zhang L, Roth JA, Liu J, Fang B. Cell to cell contact required for bystander effect of the TNF-related apoptosis-inducing ligand (TRAIL) gene. Int J Oncol 22(6):1241-5, 2003. PMID: 12738989.
159. Lin T, Gu J, Zhang L, Davis JJ, Huang X, Cabbini G, Ji L, Fang B. Enhancing adenovirus-mediated gene transfer in vitro and in vivo by addition of protamine and hydrocortisone. J Gene Med 5(10):868-75, 2003. PMID: 14533195.
160. Lin T, Zhang L, Davis J, Gu J, Nishizaki M, Ji L, Roth JA, Xiong M, Fang B. Combination of TRAIL gene therapy and chemotherapy enhances antitumor and antimetastasis effects in chemosensitive and chemoresistant breast cancers. Mol Ther 8(3):441-8, 2003. PMID: 12946317.
161. Swisher SG, Roth JA, Komaki R, Gu J, Lee JJ, Hicks M, Ro JY, Hong WK, Merritt JA, Ahrar K, Atkinson NE, Correa AM, Dolormente M, Dreiling L, El-Naggar AK, Fossella F, Francisco R, Glisson B, Grammer S, Herbst R, Huaringa A, Kemp B, Khuri FR, Kurie JM, Liao Z, McDonnell TJ, Morice R, Morello F, Munden R, Papadimitrakopoulou V, Pisters KM, Putnam JB, Sarabia AJ, Shelton T, Stevens C, Shin DM, Smythe WR, Vaporciyan AA, Walsh GL, Yin M. Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy. Clin Cancer Res 9(1):93-101, 2003. PMID: 12538456.
162. Gu J, Andreeff M, Roth JA, Fang B. hTERT promoter induces tumor-specific Bax gene expression and cell killing in syngenic mouse tumor model and prevents systemic toxicity. Gene Ther 9:30-7, 2002. PMID: 11850720.
163. Gu J, Zhang L, Huang X, Lin T, Yin M, Xu K, Ji L, Roth JA, Fang B. A novel single tetracycline-regulative adenoviral vector for tumor-specific Bax gene expression and cell killing in vitro and in vivo. Oncogene 21(31):4757-64, 2002. PMID: 12101414.
164. Huang X, Lin T, Gu J, Zhang L, Roth JA, Stephens LC, Yu Y, Liu J, Fang B. Combined TRAIL and Bax gene therapy prolonged survival in mice with ovarian cancer xenograft. Gene Ther 9:1379-86, 2002. PMID: 12365003.
165. Lin T, Gu J, Zhang L, Huang X, Stephens LC, Curley SA, Fang B. Targeted expression of green fluorescent protein/tumor necrosis factor-related apoptosis-inducing ligand fusion protein from human telomerase reverse transcriptase promoter elicits antitumor activity without toxic effects on primary human hepatocytes. Cancer Res 62(13):3620-5, 2002. PMID: 12097263.
166. Lin T, Huang X, Gu J, Zhang L, Roth JA, Xiong M, Curley SA, Yu Y, Hunt KK, Fang B. Long-term tumor-free survival from treatment with the GFP-TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells. Oncogene 21(52):8020-8, 2002. PMID: 12439752.
167. Pirocanac EC, Nassirpour R, Yang M, Wang J, Nardin SR, Gu J, Fang B, Moossa AR, Hoffman RM, Bouvet M. Bax-induction gene therapy of pancreatic cancer. J Surg Res 106(2):346-351, 2002. PMID: 12175991.
168. Zhang L, Gu J, Lin T, Huang X, Roth JA, Fang B. Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line. Gene Ther 9:1262-70, 2002. PMID: 12215894.
169. Tanyi JL, Lapushin R, Eder A, Auersperg N, Tabassam FH, Roth JA, Gu J, Fang B, Mills GB, Wolf J. Identification of tissue- and cancer-selective promoters for the introduction of genes into human ovarian cancer cells. Gynecol Oncol 85(3):451-8, 2002. PMID: 12051873.
170. Kagawa S, Gu J, Honda T, McDonnell TJ, Swisher SG, Roth JA, Fang B. Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death. Clin Cancer Res 7:1474-80, 2001. PMID: 11350920.
171. Kagawa S, He C, Gu J, Koch P, Rha SJ, Roth JA, Curley SA, Stephens LC, Fang B. Antitumor activity and bystander effects of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) gene. Cancer Res 61:3330-8, 2001. PMID: 11309289.
172. Koch PE, Guo ZS, Kagawa S, Gu J, Roth JA, Fang B. Augmenting transgene expression from carcinoembryonic antigen (CEA) promoter via a GAL4 gene regulatory system. Mol Ther 3:278-83, 2001. PMID: 11273768.
173. Gu J, Kagawa S, Takakura M, Kyo S, Inoue M, Roth JA, Fang B. Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers. Cancer Res 60:5359-64, 2000. PMID: 11034071.
174. Kagawa S, Gu J, Swisher SG, Ji L, Roth JA, Lai D, Stephens LC, Fang B. Antitumor effect of adenovirus-mediated Bax gene transfer on p53-sensitive and p53-resistant cancer lines. Cancer Res 60:1157-61, 2000. PMID: 10728665.
175. Perumal K, Gu J, Reddy R. Evolutionary conservation of post-transcriptional 3' end adenylation of small RNAs: S. cerevisiae signal recognition particle RNA and U2 small nuclear RNA are post-transcriptionally adenylated. Mol. Cell. Biochem 208:99-109, 2000.
176. Chen Y, Sinha K, Perumal K, Gu J, Reddy R. Accurate 3'-end processing and adenylation of human signal recognition particle RNA and Alu RNA in vitro. J. Biol. Chem 273:35023-35031, 1998.
177. Gu J, Shimba S, Nomura N, Reddy R. Characterization of a novel nuclear RNA-binding protein p110nrb. Biochim. Biophys. Acta 1399:1-9, 1998.
178. Sinha K, Gu J, Chen Y, Reddy R. Adenylation of small RNAs in human cells. J. Biol. Chem 273:6853-6859, 1998.
179. Gu J, Shumyatsky G, Makan N, Reddy R. Formation of 2', 3'-cyclic phosphates at the 3'-end of human U6 small nuclear RNA in vitro: identification of 2', 3'-cyclic phosphates at the 3'-end of human SRP and MRP RNAs. J. Biol. Chem 272:21989-21993, 1997.
180. Gu J, Patton JR, Shimba S, Reddy R. Localization of modified nucleotides in S. pombe spliceosomal small nuclear RNAs: modified nucleotides are clustered in functionally important regions. RNA 2:909-918, 1996.

Invited Articles

1. Baruah A, Buttar N, Chandra R, Chen X, Clemons NJ, Compare D, El-Rifai W, Gu J, Houchen CW, Koh SY, Li W, Nardone G, Phillips WA, Sharma A, Singh I, Upton MP, Vega KJ, Wu X. Translational research on Barrett's esophagus. Ann N Y Acad Sci 1325(1):170-86, 2014.
2. Gu J, Wang Y, Wu X. MicroRNA in the pathogenesis and prognosis of esophageal cancer. Curr Pharm Des 19(7):1292-300, 2013. e-Pub 2012. PMID: 23092349.
3. Chang DW, Gu J, Wu X. Germline prognostic markers for urinary bladder cancer: Obstacles and opportunities. Urol Oncol 30(4):524-32, 2012. PMID: 22742565.
4. Gu J, Wu X. Genetic Susceptibility to Bladder Cancer Risk and Outcome. Per Med 8(3):365-74, 2011. PMID: 21927616.
5. Saeki N, Gu J, Yoshida T, Wu X. Prostate stem cell antigen: a Jekyll and Hyde molecule?. Clin Cancer Res 16(14):3533-8, 2010. e-Pub 2010. PMID: 20501618.
6. Hildebrandt MA, Gu J, Wu X. Pharmacogenomics of platinum-based chemotherapy in NSCLC. Expert Opin Drug Metab Toxicol 5(7):745-55, 2009. PMID: 19442035.
7. Wu X, Ros MM, Gu J, Kiemeney L. Epidemiology and genetic susceptibility to bladder cancer. BJU Int 102(9 Pt B):1207-15, 2008. PMID: 19035883.
8. Horikawa Y, Gu J, Wu X. Genetic susceptibility to bladder cancer with an emphasis on gene-gene and gene-environmental interactions. Curr Opin Urol 18:493-8, 2008.
9. Wu X, Lin X, Dinney CP, Gu J, Grossman HB. Genetic polymorphism related to bladder cancer. Front Biosc 12:192-213, 2007.
10. Wu X, Gu J, Spitz MR. Mutagen sensitivity: a genetic predisposing factor for cancer. Cancer Res 67:3493-5, 2007.
11. Gu J, Grossman HB, Dinney CP, Wu X. The pharmacogenetic impact of inflammatory genes on bladder cancer recurrence. Pharmacogenomics 6(6):575-84, 2005. PMID: 16142998.
12. Gu J, Fang B. Telomerase promoter-driven cancer gene therapy. Cancer Biol Ther 2:S64-70, 2003.
13. Gu J, Chen Y, Reddy R. Small RNA database. Nucleic Acid Res 26:160-162, 1998.
14. Gu J, Reddy R. Small RNA database. Nucleic Acid Res 25:98-101, 1997.
15. Gu J, Reddy R. Small RNA database. Nucleic Acid Res 24:73-75, 1996.
16. Gu J, Reddy R. Compilation of small RNA sequences. Nucleic Acid Res 22:3181-3182, 1994.

Editorials

1. Wu X, Gu J. Heritability of prostate cancer: a tale of rare variants and common single nucleotide polymorphisms. Ann Transl Med 4(10):206, 2016. PMID: 27294245.
2. Gu J. Leukocyte Telomere Length and Cancer Risk: A Dynamic Problem. EBioMedicine 2(6):493-4, 2015. PMID: 26286096.

Book Chapters

1. Gu J, Wu X. Telomere Integrity and Length and Cancer Risk. In: Telomeres, Diet and Human Disease: Advances and Therapeutic Opportunities. CRC Press, 55-68, 2017.
2. Bernstein L, Pu X, Gu J. Hormones and the Etiology of Cancer. In: Holland-Frei Cancer Medicine Ninth Edition. John Wiley & Sons, Inc, 2017.
3. Wu X, Gu J. Biomarkers Assessing Risk of Cancer. In: The Molecular Basis of Cancer. 4th. Elsevier, 2014.
4. Wu X, Shu X, Chow WH, Gu J. Epidemiology of Renal Cell Carcinoma. In: Renal Cell Carcinoma, 2014.
5. Gu J, Wu X.. MicroRNAs in Esophageal Cancer. In: MicroRNAs in Cancer Translational Research. Springer Science, 201-222, 2011.
6. Wu X, Gu J. Pharmacogenetics of lung cancer. In: Lung Cancer: Prevention, Management and Emerging Therapies. Humana Press, 87-106, 2010.
7. Wu X, Gu J, Spitz MR. Strategies to identify pharmacogenomic biomarkers: candidate gene, pathway-based, and genome-wide approaches. In: Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response. Humana Press, 353-370, 2009.
8. Wu X, Gu J. Pharmacogenetics in cancer chemotherapy. In: Molecular Epidemiology: Applications in Cancer and Other Human Diseases. Informa Healthcare USA, Inc: New York, 29-38, 2008.
9. Hazra A, Gu J, Wu X. Genetic susceptibility to bladder cancer. In: Textbook of Bladder Cancer. Martin Dunitz & Parthenon Publishing, 27-36, 2006.
10. Gu J, Reddy R. Cellular RNAs: varied roles. In: Encyclopedia of Life Sciences. Nature Publishing Group, Macmillan Reference Ltd, 2001.