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John D. Hazle, Ph.D., FAAPM, FACR, FAIMBE

Department of Imaging Physics, Division of Diagnostic Imaging

About Dr. John D. Hazle

Dr. John D. Hazle is a medical physicist with over 30 years of academic experience. He is board-certified and licensed in Texas for both therapeutic and diagnostic medical physics. His primary research interests are image-guided therapy, pre-clinical imaging, novel early detection technologies and computational modeling. Dr. Hazle shares leadership of the Image Guided Therapy Lab with Dr. Jason Stafford where their work primarily focuses on developing novel approaches to image temperature using MRI. Dr. Hazle has been the Director of the NCI funded Small Animal Cancer Imaging Research Facility for 20 years and was the Director of the NCI funded Experimental Cancer Imaging Research Program from 2008-2012. He has won numerous awards, most recently MD Anderson's President's Recognition for Faculty Excellence Award in 2014.

Dr. Hazle serves on multiple institutional committees, engages as a medical imaging expert with industry partners, and is currently a journal reviewer for six peer reviewed scientific journals. He is a past President of the American Association of Physicists in Medicine and the Commission for Accreditation of Medical Physics Education Programs. Dr. Hazle is considered a renowned expert in biomedical imaging and MRI physics. He is frequently an invited presenter at national and international conferences. Dr. Hazle also holds the Bernard W. Biedenharn Chair in Cancer Research and has a faculty appointment with The University of Texas Graduate School of Biomedical Sciences.

Primary Appointment

Deputy Division Head for Research, Division of Diagnostic Imaging, Department of Diagnostic Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX

Professor (Joint appointment), Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX

Professor, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX

Professor (Joint appointment), Department of Radiology, University of Texas Medical School, Houston, TX

Faculty, Department of Keck Center for Computational and Structural Biology, Rice University, Houston, TX

Chairman, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX

Faculty, The University of Texas Graduate School of Biomedical Sciences, Houston, TX

Education & Training

Degree-Granting Education

1989	The University of Texas Graduate School of Biomedical Sciences, Houston, Texas, US, Ph.D. in Biophysics
1983	University of Kentucky, Lexington, Kentucky, US, M.S. in Medical Physics
1981	University of Kentucky, Lexington, Kentucky, US, BS in Physics

Board Certifications

1998	American Board of Medical Physics (MRI Physics)
1996	American Board of Radiology (Diagnostic Radiologic Physics)
1992	American Board of Radiology (Therapeutic Radiological Physics)

Experience & Service

Institutional Committee Activities

Chair, Educational Functional Committee Meeting, 2013 - 2019

Co-Chair, Research Functional Committee, 2013 - Present

Member, Institutional Research Executive Committee, 2012 - 2016

Chair, Executive Committee of the Science Faculty, 2011 - 2012

Member, Graduate Education Committee, 2011 - 2014

Member, Management Committee, 2010 - 2011

Member, Technology Task Force, 2010 - 2015

Member, Research Strategies Committee, 2010 - 2011

Member, Women Faculty Programs Advisory Committee, 2009 - 2014

Member, Research Council, 2009 - 2017

Member, Membership Committee of the Graduate School of Biomedical Sciences, 2008 - 2010

Member, Executive Committee of the Science Faculty, 2007 - 2012

Chair, Research Operations Committee, Center for Advanced Biomedical Imaging Research, 2007 - 2011

Member, Radiation Oncology Chair Search Committee, 2006

Member, Biomedical Engineering Chair Search Committee, 2006 - 2007

Chair, Alfred G. Knudson Award Committee, 2005

Member, Center for Advanced Biomedical Imaging Research, Steering Committee, 2004 - Present

Member, Faculty Compensation Committee, 2004 - 2006

Member, Research Grants Committee, 2003 - 2011

Member, Multidisciplinary Research Advisory Committee, 2002 - 2011

Member, Technology Review Committee, 2002 - 2012

Member, Executive Committee of the Science Faculty, 2002 - 2011

Member, Animal Care and Use Committee, 2000 - 2003

Chair, Radiation Physics Chair Search Committee, 2000 - 2001

Member, Executive Committee, Faculty Senate, 1999 - 2001

Faculty Senate, Member, Tenure Issues Committee, 1998 - 2001

Member, Graduate School of Biomedical Sciences, Academic Affairs Committee, 1996 - 1999

Diagnostic Radiology Representative, Faculty Senate, 1995 - 2001

Honors & Awards

2020	Fellow, American Institute for Medical and Biological Engineering (AIMBE)
2015	2015 Provost's Distinguished Clinical Faculty Mentor Award, The University of Texas MD Anderson Cancer Center
2014	President's Recognition for Faculty Excellence, UT MD Anderson Cancer Center
2012 - 2018	Representative, The National Academies of Sciences-Engineering-Medicine
2011	Fellow, American College of Radiology
2007	Outstanding Alumni Award, The University of Kentucky College of Health Sciences
2004 - 2005	Certificate of Excellence in Research Mentorship, University of Texas Center for Biomedical Engineering
2003	Fellow, American Association of Physicists in Medicine
1999	Tenure, The University of Texas MD Anderson Cancer Center
1998	Re-appointment with Commendation, Graduate School of Biomedical Sciences
1996	Cum Laude Award, Radiological Society of North America
1995	Certificate of Merit, Radiological Society of North America
1995	Student Marshal, Graduation Ceremony, Graduate School of Biomedical Sciences
1995 - 2001	Dean’s Excellence Award, Graduate School of Biomedical Sciences, The University of Texas Health Science Center
1994	Dean’s Excellence Award, Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center and Health Science Center, Houston, TX

Professional Memberships

Academy for Radiology & Biomedical Imaging Research

2018 - Present

NIH Center for Scientific Review

2014

The National Academies of Sciences-Engineering-Medicine

2012 - 2019

Commission on Accreditation of Medical Physics Education Programs

2005 - 2011

American Association of Cancer Researchers

2003 - Present

American Board of Radiology

1998

Southwest Chapter of the American Association of Physicists in Medicine

1994 - 1995

American College of Radiology

1991 - Present

Texas Radiological Society

1991 - Present

Radiological Society of North America

1990 - Present

International Society of Magnetic Resonance in Medicine

1986 - Present

American Association of Physicists in Medicine

1983 - Present

Selected Publications

Peer-Reviewed Articles

Drazinos P, Gatos I, Katsakiori PF, Tsantis S, Syrmas E, Spiliopoulos S, Karnabatidis D, Theotokas I, Zoumpoulis P, Hazle JD, Kagadis GC. Comparison of deep learning schemes in grading non-alcoholic fatty liver disease using B-mode ultrasound hepatorenal window images with liver biopsy as the gold standard. Phys Med 129:104862, 2024. e-Pub 2024. PMID: 39626614.
Salehjahromi, M, Karpinets, T, Sujit, S, Qayati, M, Chen, P, Aminu, M, Saad, MB, Bandyopadhyay, R, Hong, L, Sheshadri, A, Lin, J, Antonoff, MB, Sepesi, B, Ostrin, EJ, Toumazis, I, Huang, P, Cheng, C, Cascone, T, Vokes, N, Behrens, C, Siewerdsen, JH, Hazle, JD, Chang, JY, Zhang, J, Lu, Y, Godoy, M, Chung, C, Jaffray, D, Wistuba, II, Lee, JJ, Vaporciyan, AA, Gibbons, DL, Gladish, G, Heymach, JV, Wu, CC, Zhang, J, Wu, J. Synthetic PET from CT improves diagnosis and prognosis for lung cancer. Cell Reports Medicine 5(3), 2024. e-Pub 2024. PMID: 38471502.
Plachouris, D, Eleftheriadis, V, Nanos, T, Papathanasiou, N, Sarrut, D, Papadimitroulas, P, Savvidis, G, Vergnaud, L, Salvadori, J, Imperiale, A, Visvikis, D, Hazle, JD, Kagadis, GC. A radiomic- and dosiomic-based machine learning regression model for pretreatment planning in 177Lu-DOTATATE therapy. Medical physics 50(11):7222-7235, 2023. e-Pub 2023. PMID: 37722718.
Saad, MB, Hong, L, Aminu, M, Vokes, N, Chen, P, Salehjahromi, M, Qin, K, Sujit, S, Lu, X, Young, E, Al-Tashi, Q, Qureshi, R, Wu, CC, Carter, B, Lin, SH, Lee, PP, Gandhi, S, Chang, JY, Li, R, Gensheimer, MF, Wakelee, HA, Neal, JW, Lee, HS, Cheng, C, Velcheti, V, Lou, Y, Petranovic, M, Rinsurongkawong, W, Le, X, Rinsurongkawong, V, Spelman, AR, Elamin, YY, Vailati Negrao, M, Skoulidis, F, Gay, CM, Cascone, T, Antonoff, MB, Sepesi, B, Lewis, J, Wistuba, II, Hazle, JD, Chung, C, Jaffray, D, Gibbons, DL, Vaporciyan, AA, Lee, JJ, Heymach, JV, Zhang, J, Wu, J. Predicting benefit from immune checkpoint inhibitors in patients with non-small-cell lung cancer by CT-based ensemble deep learning. The Lancet Digital Health 5(7):e404-e420, 2023. e-Pub 2023. PMID: 37268451.
Ho ML, Arnold CW, Decker SJ, Hazle JD, Krupinski EA, Mankoff DA. Institutional strategies to maintain and grow imaging research during the COVID-19 pandemic. Acad Radiol 30(22):00701-2, 2023. e-Pub 2023. PMID: 36764883.
Moawad AW, Morshid A, Khalaf AM, Elmohr MM, Hazle JD, Fuentes D, Badawy M, Kaseb AO, Hassan M, Mahvash A, Szklaruk J, Qayyum A, Abusaif A, Bennett WC, Nolan TS, Camp B, Elsayes KM. Multimodality annotated hepatocellular carcinoma data set including pre-and post-TACE with imaging segmentation. Sci Data 10(1):33, 2023. e-Pub 2023. PMID: 36653372.
Burmeister JW, Coffey CW, Hazle JD, Kirby N, Kuang Y, Lamba MA, Loughery B, Papanikolaou N. AAPM Report 373: The content, structure, and value of the Professional Doctorate in Medical Physics (DMP). J Appl Clin Med Phys 23(10):e13771, 2022. e-Pub 2022. PMID: 36107002.
El Hussein S, Chen P, Medeiros LJ, Hazle JD, Wu J, Khoury JD. Artificial intelligence-assisted mapping of proliferation centers allows the distinction of accelerated phase from large cell transformation in chronic lymphocytic leukemia. Mod Pathol 35(8):1121-1125, 2022. e-Pub 2022. PMID: 35132162.
Chen P, El Hussein S, Xing F, Aminu M, Kannapiran A, Hazle JD, Medeiros LJ, Wistuba II, Jaffray D, Khoury JD, Wu J. Chronic Lymphocytic Leukemia Progression Diagnosis with Intrinsic Cellular Patterns via Unsupervised Clustering. Cancers (Basel) 14(10), 2022. e-Pub 2022. PMID: 35626003.
Kim CS, Nevozhay D, Aburto RR, Pehere A, Pang L, Dillard R, Wang Z, Smith C, Mathieu KB, Zhang M, Hazle JD, Bast RC, Sokolov K. One-Pot, One-Step Synthesis of Drug-Loaded Magnetic Multimicelle Aggregates. Bioconjug Chem 33(5):969-981, 2022. e-Pub 2022. PMID: 35522527.
Jimenez JE, Abdelhafez A, Mittendorf EA, Elshafeey N, Yung JP, Litton JK, Adrada BE, Candelaria RP, White J, Thompson AM, Huo L, Wei P, Tripathy D, Valero V, Yam C, Hazle JD, Moulder SL, Yang WT, Rauch GM. A model combining pretreatment MRI radiomic features and tumor-infiltrating lymphocytes to predict response to neoadjuvant systemic therapy in triple-negative breast cancer. Eur J Radiol 149:110220, 2022. e-Pub 2022. PMID: 35193025.
Jimenez JE, Dai D, Xu G, Zhao R, Li T, Pan T, Wang L, Lin Y, Wang Z, Jaffray D, Hazle JD, Macapinlac HA, Wu J, Lu Y. Lesion-Based Radiomics Signature in Pretherapy 18F-FDG PET Predicts Treatment Response to Ibrutinib in Lymphoma. Clin Nucl Med 47(3):209-218, 2022. e-Pub 2022. PMID: 35020640.
Plachouris D, Mountris KA, Papadimitroulas P, Spyridonidis T, Katsanos K, Apostolopoulos D, Papathanasiou N, Hazle JD, Visvikis D, Kagadis GC. Clinical Evaluation of a Three-Dimensional Internal Dosimetry Technique for Liver Radioembolization with 90Y Microspheres Using Dose Voxel Kernels. Cancer Biother Radiopharm 36(10):809-819, 2021. e-Pub 2021. PMID: 33656372.
Plachouris, D, Tzolas, I, Gatos, I, Papadimitroulas, P, Spyridonidis, T, Apostolopoulos, D, Papathanasiou, N, Visvikis, D, Plachouri, KM, Hazle, JD, Kagadis, GC. A deep-learning-based prediction model for the biodistribution of 90Y microspheres in liver radioembolization. Medical physics 48(11):7427-7438, 2021. e-Pub 2021. PMID: 34628667.
Moawad, AW, Ahmed, AA, Fuentes, DA, Hazle, JD, Habra, MA, Elsayes, KM. Machine learning-based texture analysis for differentiation of radiologically indeterminate small adrenal tumors on adrenal protocol CT scans. Abdominal Radiology 46(10):4853-4863, 2021. e-Pub 2021. PMID: 34085089.
McGee, KP, Tyagi, N, Bayouth, JE, Cao, M, Fallone, BG, Glide-Hurst, CK, Goerner, FL, Green, OL, Kim, T, Paulson, ES, Yanasak, NE, Jackson, EF, Goodwin, JH, Dieterich, S, Jordan, DW, Hugo, G, Bernstein, M, Balter, JM, Kanal, KM, Hazle, JD, Pelc, NJ. Findings of the AAPM Ad Hoc committee on magnetic resonance imaging in radiation therapy. Medical physics 48(8):4523-4531, 2021. e-Pub 2021. PMID: 34231224.
Schellingerhout, D, Jacobsen, MC, Le Roux, LG, Johnson, JM, Baladandayuthapani, V, Hwang, K, Hazle, JD, Schomer, DF, Cody, D. The Calcium Versus Hemorrhage Trial. Investigative radiology 56(6):385-393, 2021. e-Pub 2021. PMID: 33534507.
Gates EDH, Weinberg JS, Prabhu SS, Lin JS, Hamilton J, Hazle JD, Fuller GN, Baladandayuthapani V, Fuentes DT, Schellingerhout D. Estimating Local Cellular Density in Glioma Using MR Imaging Data. AJNR Am J Neuroradiol 42(1):102-108, 2021. e-Pub 2021. PMID: 33243897.
Kagadis GC, Drazinos P, Gatos I, Tsantis S, Papadimitroulas P, Spiliopoulos S, Karnabatidis D, Theotokas I, Zoumpoulis P, Hazle JD. Deep learning networks on chronic liver disease assessment with fine-tuning of shear wave elastography image sequences. Phys Med Biol 65(21):215027, 2020. e-Pub 2020. PMID: 32998480.
Gates EDH, Lin JS, Weinberg JS, Prabhu SS, Hamilton J, Hazle JD, Fuller GN, Baladandayuthapani V, Fuentes DT, Schellingerhout D. Imaging-Based Algorithm for the Local Grading of Glioma. AJNR Am J Neuroradiol 41(3):400-407, 2020. e-Pub 2020. PMID: 32029466.
Elhalawani H, Awan MJ, Ding Y, Mohamed ASR, Elsayes AK, Abu-Gheida I, Wang J, Hazle J, Gunn GB, Lai SY, Frank SJ, Ginsberg LE, Rosenthal DI, Fuller CD. Data from a terminated study on iron oxide nanoparticle magnetic resonance imaging for head and neck tumors. Sci Data 7(1):63, 2020. e-Pub 2020. PMID: 32081849.
Moawad AW, Fuentes D, Khalaf AM, Blair KJ, Szklaruk J, Qayyum A, Hazle JD, Elsayes KM. Feasibility of Automated Volumetric Assessment of Large Hepatocellular Carcinomas' Responses to Transarterial Chemoembolization. Front Oncol 10:572, 2020. e-Pub 2020. PMID: 32457831.
Khalaf AM, Fuentes D, Morshid A, Kaseb AO, Hassan M, Hazle JD, Elsayes KM. Hepatocellular carcinoma response to transcatheter arterial chemoembolisation using automatically generated pre-therapeutic tumour volumes by a random forest-based segmentation protocol. Clin Radiol 74(12):974.e13-974.e20, 2019. e-Pub 2019. PMID: 31521326.
Elmohr MM, Fuentes D, Habra MA, Bhosale PR, Qayyum AA, Gates E, Morshid AI, Hazle JD, Elsayes KM. Machine learning-based texture analysis for differentiation of large adrenal cortical tumours on CT. Clin Radiol 74(10):818.e1-818.e7, 2019. e-Pub 2019. PMID: 31362884.
Thrower SL, Kandala SK, Fuentes D, Stefan W, Sowko N, Huang M, Mathieu K, Hazle JD. A compressed sensing approach to immobilized nanoparticle localization for superparamagnetic relaxometry. Phys Med Biol 64(19):194001, 2019. e-Pub 2019. PMID: 31422952.
Morshid A, Elsayes KM, Khalaf AM, Elmohr MM, Yu J, Kaseb AO, Hassan M, Mahvash A, Wang Z, Hazle JD, Fuentes D. A machine learning model to predict hepatocellular carcinoma response to transcatheter arterial chemoembolization. Radiol Artif Intell 1(5), 2019. e-Pub 2019. PMID: 31858078.
Hormuth DA, Sorace AG, Virostko J, Abramson, RG, Bhujwalla ZM, Enriquez-Navas P, Gillies R, Hazle JD, Mason RP, Quarles CC, Weis JA, Whisenant JG, Xu J, Yankeelov TE. Translating Preclinical MRI Methods to Clinical Oncology. International Society for Magnetic Resonance in Medicine 50(5):1377-1392, 2019. e-Pub 2019.
Fuentes D, Ahmed K, Lin JS, Abdel-Wahab R, Kaseb AO, Hassan M, Szklaruk J, Morshid A, Hazle JD, Qayyum A, Elsayes KM. Automated Volumetric Assessment of Hepatocellular Carcinoma Response to Sorafenib: A Pilot Study. J Comput Assist Tomogr 43(3):499-506, 2019. e-Pub 2019. PMID: 31082956.
Fuentes D, Ahmed K, Lin JS, Abdel-Wahab R, Kaseb AO, Hassan M, Szklaruk J, Morshid A, Hazle JD, Qayyum A, Elsayes KM. Automated Volumetric Assessment of Hepatocellular Carcinoma Response to Sorafenib: A Pilot Study. J Comput Assist Tomogr. e-Pub 2019. PMID: 31082984.
Gatos I, Tsantis S, Spiliopoulos S, Karnabatidis D, Theotokas I, Zoumpoulis P, Loupas T, Hazle JD, Kagadis GC. Temporal stability assessment in shear wave elasticity images validated by deep learning neural network for chronic liver disease fibrosis stage assessment. Med Phys 46(5):2298-2309, 2019. e-Pub 2019. PMID: 30929260.
Gates EDH, Lin JS, Weinberg JS, Hamilton J, Prabhu SS, Hazle JD, Fuller GN, Baladandayuthapani V, Fuentes D, Schellingerhout D. Guiding the First Biopsy in Glioma Patients using Estimated Ki67 Maps Derived from Magnetic Resonance Imaging: Conventional versus Advanced Imaging. Neuro Oncol 21(4):527-536, 2019. e-Pub 2019. PMID: 30657997.
Mitchell D, Fahrenholtz S, MacLellan C, Bastos D, Rao G, Prabhu S, Weinberg J, Hazle J, Stafford J, Fuentes D. A heterogeneous tissue model for treatment planning for magnetic resonance guided laser interstitial thermal therapy. Int J Hyperthermia 34(7):943-952, 2018. e-Pub 2018. PMID: 29343140.
MacLellan CJ, Fuentes D, Prabhu S, Rao G, Weinberg JS, Hazle JD, Stafford RJ. A methodology for thermal dose model parameter development using perioperative MRI. Int J Hyperthermia 34(6):1-10, 2018. e-Pub 2018. PMID: 28830311.
Xiao Y, Xu D, Ju H, Yang C, Wang L, Wang J, Hazle JD, Wang D. Application value of biplane transrectal ultrasonography plus ultrasonic elastosonography and contrast-enhanced ultrasonography in preoperative T staging after neoadjuvant chemoradiotherapy for rectal cancer. Eur J Radiol 104:20-25, 2018. e-Pub 2018. PMID: 29857861.
Development Cooperative JHANR. Publisher Correction: A Multi-Institutional Comparison of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Parameter Calculations. Sci Rep 8(1):4422, 2018. e-Pub 2018. PMID: 29520065.
Fahrenholtz SJ, Madankan R, Danish S, Hazle JD, Stafford RJ, Fuentes D. Theoretical model for laser ablation outcome predictions in brain: calibration and validation on clinical MR thermometry images. Int J Hyperthermia 34(1):1-11, 2018. e-Pub 2018. PMID: 28540820.
Weng HH, Noll KR, Johnson JM, Prabhu SS, Tsai YH, Chang SW, Huang YC, Lee JD, Yang JT, Yang CT, Tsai YH, Yang CY, Hazle JD, Schomer DF, Liu HL. Accuracy of Presurgical Functional MR Imaging for Language Mapping of Brain Tumors: A Systematic Review and Meta-Analysis. Radiology 286(2):162971, 2018. e-Pub 2018. PMID: 28980887.
Hsu AL, Hou P, Johnson JM, Wu CW, Noll KR, Prabhu SS, Ferguson SD, Kumar VA, Schomer DF, Hazle JD, Chen JH, Liu HL. IClinfMRI Software for Integrating Functional MRI Techniques in Presurgical Mapping and Clinical Studies. Front Neuroinform 12:11, 2018. e-Pub 2018. PMID: 29593520.
Sovizi J, Mathieu KB, Thrower SL, Stefan W, Hazle JD, Fuentes D. Gaussian process classification of superparamagnetic relaxometry data: Phantom study. Artif Intell Med 82:47-59, 2017. e-Pub 2017. PMID: 28911905.
Ger RB, Mohamed ASR, Awan MJ, Ding Y, Li K, Fave XJ, Beers AL, Driscoll B, Elhalawani H, Hormuth DA, Houdt PJV, He R, Zhou S, Mathieu KB, Li H, Coolens C, Chung C, Bankson JA, Huang W, Wang J, Sandulache VC, Lai SY, Howell RM, Stafford RJ, Yankeelov TE, Heide UAV, Frank SJ, Barboriak DP, Hazle JD, Court LE, Kalpathy-Cramer J, Fuller CD. A Multi-Institutional Comparison of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Parameter Calculations. Sci Rep 7(1):11185, 2017. e-Pub 2017. PMID: 28894197.
Gatos I, Tsantis S, Spiliopoulos S, Karnabatidis D, Theotokas I, Zoumpoulis P, Loupas T, Hazle JD, Kagadis GC. A Machine-Learning Algorithm Toward Color Analysis for Chronic Liver Disease Classification, Employing Ultrasound Shear Wave Elastography. Ultrasound Med Biol 43(9):1797-1810, 2017. e-Pub 2017. PMID: 28634041.
Yung JP, Fuentes D, MacLellan CJ, Maier F, Liapis Y, Hazle JD, Stafford RJ. Referenceless Magnetic Resonance Temperature Imaging using Gaussian Process Modeling. Med Phys 44(7):3545-3555, 2017. e-Pub 2017. PMID: 28317125.
Gatos I, Tsantis S, Karamesini M, Spiliopoulos S, Karnabatidis D, Hazle JD, Kagadis GC. Focal liver lesions segmentation and classification in nonenhanced T2-weighted MRI. Med Phys 44(7):3695-3705, 2017. e-Pub 2017. PMID: 28432822.
Zheng B, Yu E, Orendorff R, Lu K, Konkle JJ, Tay ZW, Hensley D, Zhou XY, Chandrasekharan P, Saritas EU, Goodwill PW, Hazle JD, Conolly SM. Seeing SPIOs Directly In Vivo with Magnetic Particle Imaging. Mol Imaging Biol 19(3):385-390, 2017. e-Pub 2017. PMID: 28396973.
Lin JS, Fuentes DT, Chandler A, Prabhu SS, Weinberg JS, Baladandayuthapani V, Hazle JD, Schellingerhout D. Performance Assessment for Brain MR Imaging Registration Methods. AJNR Am J Neuroradiol 38(5):973-980, 2017. e-Pub 2017. PMID: 28279984.
Song H, Ruan D, Liu W, Stenger VA, Pohmann R, Fernández-Seara MA, Nair T, Jung S, Luo J, Motai Y, Ma J, Hazle JD, Gach HM. Respiratory motion prediction and prospective correction for free-breathing arterial spin labeled perfusion MRI of the kidneys. Med Phys 44(3):962-973, 2017. e-Pub 2017. PMID: 28074528.
Son JB, Hwang KP, Madewell JE, Bayram E, Hazle JD, Low RN, Ma J. A flexible fast spin echo triple-echo Dixon technique. Magn Reson Med 77(3):1049-1057, 2017. e-Pub 2017. PMID: 26982770.
Madankan R, Stefan W, Fahrenholtz SJ, MacLellan CJ, Hazle JD, Stafford RJ, Weinberg JS, Rao G, Fuentes D. Accelerated magnetic resonance thermometry in the presence of uncertainties. Phys Med Biol 62(1):214-245, 2017. e-Pub 2017. PMID: 27991449.
Ma J, Son JB, Hazle JD. An improved region growing algorithm for phase correction in MRI. Magn Reson Med 76(2):519-29, 2016. e-Pub 2016. PMID: 26362527.
Hazle J. WE-G-204-00: Post-Graduate Training of the Next Generation of Academic Medical Physicists. Med Phys 43(6):3837, 2016. e-Pub 2016. PMID: 28046388.
Hazle J, Bhujwalla Z. MO-DE-206-00: Joint AAPM-WMIS Symposium: Metabolic Imaging of Cancer. Med Phys 43(6):3703, 2016. e-Pub 2016. PMID: 28046736.
Fahrenholtz SJ, Stafford RJ, Madankan R, Hazle JD, Fuentes D. SU-F-J-02: Flexible Training of MR-Guided Laser Ablation Models Via Global Optimization. Med Phys 43(6):3405-3406, 2016. e-Pub 2016. PMID: 28047334.
Hazle JD, Jordan DW. Future qualification as a qualified clinical medical physicist should be restricted to doctoral degree holders. Med Phys 43(4):1585, 2016. e-Pub 2016. PMID: 27036557.
Gatos I, Tsantis S, Spiliopoulos S, Karnabatidis D, Theotokas I, Zoumpoulis P, Loupas T, Hazle JD, Kagadis GC. A new computer aided diagnosis system for evaluation of chronic liver disease with ultrasound shear wave elastography imaging. Med Phys 43(3):1428, 2016. e-Pub 2016. PMID: 26936727.
Messer JA, Mohamed AS, Hutcheson KA, Ding Y, Lewin JS, Wang J, Lai SY, Frank SJ, Garden AS, Sandulache V, Eichelberger H, French CC, Colen RR, Phan J, Kalpathy-Cramer J, Hazle JD, Rosenthal DI, Gunn GB, Fuller CD. Magnetic resonance imaging of swallowing-related structures in nasopharyngeal carcinoma patients receiving IMRT: Longitudinal dose-response characterization of quantitative signal kinetics. Radiother Oncol 118(2):315-22, 2016. e-Pub 2016. PMID: 26830697.
Ding Y, Hazle JD, Mohamed AS, Frank SJ, Hobbs BP, Colen RR, Gunn GB, Wang J, Kalpathy-Cramer J, Garden AS, Lai SY, Rosenthal DI, Fuller CD. Intravoxel incoherent motion imaging kinetics during chemoradiotherapy for human papillomavirus-associated squamous cell carcinoma of the oropharynx: preliminary results from a prospective pilot study. NMR Biomed 28(12):1645-54, 2015. e-Pub 2015. PMID: 26451969.
Bankson JA, Walker CM, Ramirez MS, Stefan W, Fuentes D, Merritt ME, Lee J, Sandulache VC, Chen Y, Phan L, Chou PC, Rao A, Yeung SC, Lee MH, Schellingerhout D, Conrad CA, Malloy C, Sherry AD, Lai SY, Hazle JD. Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors. Cancer Res 75(22):4708-17, 2015. e-Pub 2015. PMID: 26420214.
Rubinstein AE, Liao Z, Melancon AD, Guindani M, Followill DS, Tailor RC, Hazle JD, Court LE. Technical Note: A Monte Carlo study of magnetic-field-induced radiation dose effects in mice. Med Phys 42(9):5510, 2015. e-Pub 2015. PMID: 26328998.
Gatos I, Tsantis S, Spiliopoulos S, Skouroliakou A, Theotokas I, Zoumpoulis P, Hazle JD, Kagadis GC. A new automated quantification algorithm for the detection and evaluation of focal liver lesions with contrast-enhanced ultrasound. Med Phys 42(7):3948-3959, 2015. e-Pub 2015. PMID: 26133595.
Ding Y, Mohamed AS, Yang J, Colen RR, Frank SJ, Wang J, Wassal EY, Wang W, Kantor ME, Balter PA, Rosenthal DI, Lai SY, Hazle JD, Fuller CD. Prospective observer and software-based assessment of magnetic resonance imaging quality in head and neck cancer: Should standard positioning and immobilization be required for radiation therapy applications?. Pract Radiat Oncol 5(4):e299-308, 2015. e-Pub 2015. PMID: 25544553.
Yang L, Son JB, Ma J, Cheng S, Hazle J, Carter BW, Lin S. MO-F-CAMPUS-I-05: Quantitative ADC Measurement of Esophageal Cancer Before and After Chemoradiation. Med Phys 42(6):3579, 2015. e-Pub 2015. PMID: 26128770.
Hazle J. WE-EF-204-01: Pre-Clinical Imaging for Co-Clinical Trials. Med Phys 42(6):3680, 2015. e-Pub 2015. PMID: 26129307.
Wang J, Hwang K, Fuller C, Mohamed A, Ding Y, Frank S, Hazle J, Zhou J. SU-E-J-225: CEST Imaging in Head and Neck Cancer Patients. Med Phys 42(6):3317, 2015. e-Pub 2015. PMID: 26127617.
Ding Y, Fuller C, Mohamed A, Wang J, Hazle J. TU-F-CAMPUS-I-01: Head and Neck Squamous Cell Carcinoma: Short-Term Repeatability of Apparent Diffusion Coefficient and Intravoxel Incoherent Motion Parameters at 3.0T. Med Phys 42(6):3646, 2015. e-Pub 2015. PMID: 26129125.
Fahrenholtz SJ, Madankan R, Hazle JD, Stafford RJ, Fuentes D. SU-C-BRA-03: Prediction of Laser Induced Thermal Therapy: Results of Model Training and Cross Validation. Med Phys 42(6):3196, 2015. e-Pub 2015. PMID: 26127120.
Jacobsen MC, Dogan BE, Adrada BE, Plaxco JS, Wei W, Son JB, Hazle JD, Ma J. 3-T breast diffusion-weighted MRI by echo-planar imaging with spectral-spatial excitation or with additional spectral inversion recovery: An in vivo comparison of image quality. J Comput Assist Tomogr 39(3):343-8, 2015. e-Pub 2015. PMID: 25695868.
Maier F, Fuentes D, Weinberg JS, Hazle JD, Stafford RJ. Robust phase unwrapping for MR temperature imaging using a magnitude-sorted list, multi-clustering algorithm. Magn Reson Med 73(4):1662-8, 2015. e-Pub 2015. PMID: 24809984.
Phan L, Chou PC, Velazquez-Torres G, Samudio I, Parreno K, Huang Y, Tseng C, Vu T, Gully C, Su CH, Wang E, Chen J, Choi HH, Fuentes-Mattei E, Shin JH, Shiang C, Grabiner B, Blonska M, Skerl S, Shao Y, Cody D, Delacerda J, Kingsley C, Webb D, Carlock C, Zhou Z, Hsieh YC, Lee J, Elliott A, Ramirez M, Bankson J, Hazle J, Wang Y, Li L, Weng S, Rizk N, Wen YY, Lin X, Wang H, Wang H, Zhang A, Xia X, Wu Y, Habra M, Yang W, Pusztai L, Yeung SC, Lee MH. The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming. Nat Commun 6:7530, 2015. e-Pub 2015. PMID: 26179207.
Fahrenholtz SJ, Moon TY, Franco M, Medina D, Danish S, Gowda A, Shetty A, Maier F, Hazle JD, Stafford RJ, Warburton T, Fuentes D. A model evaluation study for treatment planning of laser-induced thermal therapy. Int J Hyperthermia 31(7):1-10, 2015. e-Pub 2015. PMID: 26368014.
Tsiapa I, Efthimiadou EK, Fragogeorgi E, Loudos G, Varvarigou AD, Bouziotis P, Kordas GC, Mihailidis D, Nikiforidis GC, Xanthopoulos S, Psimadas D, Paravatou-Petsotas M, Palamaris L, Hazle JD, Kagadis GC. (99m)Tc-labeled aminosilane-coated iron oxide nanoparticles for molecular imaging of ανβ3-mediated tumor expression and feasibility for hyperthermia treatment. J Colloid Interface Sci 433C:163-175, 2014. e-Pub 2014. PMID: 25128864.
Yeniaras E, Fuentes DT, Fahrenholtz SJ, Weinberg JS, Maier F, Hazle JD, Stafford RJ. Design and initial evaluation of a treatment planning software system for MRI-guided laser ablation in the brain. Int J Comput Assist Radiol Surg 9(4):659-67, 2014. e-Pub 2014. PMID: 24091853.
Tsantis S, Spiliopoulos S, Skouroliakou A, Karnabatidis D, Hazle JD, Kagadis GC. Multiresolution edge detection using enhanced fuzzy c-means clustering for ultrasound image speckle reduction. Med Phys 41(7):072903, 2014. e-Pub 2014. PMID: 24989413.
MacLellan CJ, Fuentes D, Elliott AM, Schwartz J, Hazle JD, Stafford RJ. Estimating nanoparticle optical absorption with magnetic resonance temperature imaging and bioheat transfer simulation. Int J Hyperthermia 30(1):47-55, 2014. e-Pub 2014. PMID: 24350668.
Rambow O, Hazle JD, Clark J, Ma J. Direct water and fat determination in two-point Dixon imaging with flexible echo times. Med Phys 40(11):112302, 2013. e-Pub 2013. PMID: 24320458.
Lin JS, Hwang KP, Jackson EF, Hazle JD, Jason Stafford R, Taylor BA. Multiparametric fat-water separation method for fast chemical-shift imaging guidance of thermal therapies. Med Phys 40(10):103302, 2013. e-Pub 2013. PMID: 24089932.
Fahrenholtz SJ, Stafford RJ, Maier F, Hazle JD, Fuentes D. Generalised polynomial chaos-based uncertainty quantification for planning MRgLITT procedures. Int J Hyperthermia 29(4):324-335, 2013. e-Pub 2013. PMID: 23692295.
Mitcham T, Homan K, Frey W, Chen YS, Emelianov S, Hazle JD, Bouchard R. Modulation of photoacoustic signal generation from metallic surfaces. J Biomed Opt 18(5):56008, 2013. e-Pub 2013. PMID: 23652344.
Fuentes D, Elliott A, Weinberg JS, Shetty A, Hazle JD, Stafford RJ. An Inverse Problem Approach to Recovery of In Vivo Nanoparticle Concentrations from Thermal Image Monitoring of MR-Guided Laser Induced Thermal Therapy. Ann Biomed Eng 41(1):100-11, 2013. e-Pub 2013. PMID: 22918665.
Ku G, Zhou M, Song S, Huang Q, Hazle JD, Li C. Copper Sulfide Nanoparticles as a New Class of Photoacoustic Contrast Agent for Deep Tissue Imaging at 1064-nm. ACS Nano 6(8):7489-7496, 2012. e-Pub 2012. PMID: 22812694.
Fahrenholtz S, Fuentes D, Stafford R, Hazle JD. SU-F-BRCD-08: Uncertainty Quantification by Generalized Polynomial Chaos for MR-Guided Laser Induced Thermal Therapy. Med Phys 39(6):3857, 2012. e-Pub 2012. PMID: 23692295.
Yung J, Fuentes D, Hazle JD, Stafford R. SU-E-J-53: A Phantom Validation Study of a 3D Background Phase Model for MR Thermometry. Med Phys 39(6):3664, 2012. e-Pub 2012. PMID: 22756022.
Chan CH, Li CF, Yang WL, Gao Y, Lee SW, Feng Z, Huang HY, Tsai KK, Flores LG, Shao Y, Hazle JD, Yu D, Wei W, Sarbassov D, Hung MC, Nakayama KI, Lin HK. The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis. Cell 149(5):1098-111, 2012. e-Pub 2012. PMID: 22632973.
Fuentes D, Yung J, Hazle JD, Weinberg JS, Stafford RJ. Kalman Filtered MR Temperature Imaging for Laser Induced Thermal Therapies. IEEE Trans Med Imaging 31(4):984-94, 2012. e-Pub 2012. PMID: 22203706.
Rylander MN, Stafford RJ, Hazle JD, Whitney J, Diller KR. Heat shock protein expression and temperature distribution in prostate tumours treated with laser irradiation and nanoshells. Int J Hyperthermia 27(8):791-801, 2011. e-Pub 2011. PMID: 22098363.
Stafford RJ, Shetty A, Elliott AM, Schwartz JA, Goodrich GP, Hazle JD. MR temperature imaging of nanoshell mediated laser ablation. Int J Hyperthermia 27(8):782-90, 2011. e-Pub 2011. PMID: 22098362.
Melancon MP, Lu W, Zhong M, Zhou M, Liang G, Elliott AM, Hazle JD, Myers JN, Li C, Stafford RJ. Targeted multifunctional gold-based nanoshells for magnetic resonance-guided laser ablation of head and neck cancer. Biomaterials 32(30):7600-7608, 2011. e-Pub 2011. PMID: 21745689.
Su JL, Bouchard RR, Karpiouk AB, Hazle JD, Emelianov SY. Photoacoustic imaging of prostate brachytherapy seeds. Biomed Opt Express 2(8):2243-2254, 2011. e-Pub 2011. PMID: 21833361.
Taylor BA, Elliott AM, Hwang KP, Shetty A, Hazle JD, Stafford RJ. Measurement of temperature dependent changes in bone marrow using a rapid chemical shift imaging technique. J Magn Reson Imaging 33(5):1128-35, 2011. e-Pub 2011. PMID: 21509871.
Schwartz DL, Bankson J, Bidaut L, He Y, Williams R, Lemos R, Thitai AK, Oh J, Volgin A, Soghomonyan S, Yeh HH, Nishii R, Mukhopadhay U, Alauddin M, Mushkudiani I, Kuno N, Krishnan S, Bornman W, Lai SY, Powis G, Hazle JD, Gelovani J. HIF-1-dependent stromal adaptation to ischemia mediates in vivo tumor radiation resistance. Mol Cancer Res 9(3):259-70, 2011. e-Pub 2011. PMID: 21364021.
Taylor BA, Elliott AM, Hwang KP, Hazle JD, Stafford RJ. Correlation between the temperature dependence of intrinsic MR parameters and thermal dose measured by a rapid chemical shift imaging technique. NMR in Biomed 24:1414-1421, 2011. e-Pub 2011. PMID: 21721063.
Fuentes D, Walker C, Elliott A, Shetty A, Hazle JD, Stafford RJ. Magnetic resonance temperature imaging validation of a bioheat transfer model for laser-induced thermal therapy. Int J Hyperthermia 27(5):453-64, 2011. e-Pub 2011. PMID: 21756043.
Black PC, Shetty A, Brown GA, Esparza-Cross E, Metwalli AR, Agarwal PK, McConkey DJ, Hazle JD, Dinney CP. Validating bladder cancer xenograft bioluminescence with magnetic resonance imaging: the significance of hypoxia and necrosis. British J Urol 106(11):1799-804, 2010. e-Pub 2010. PMID: 20500508.
Yung JP, Shetty A, Eliott A, Weinberg JS, McNichols RJ, Gowda A, Hazle JD, Stafford RJ. Quantitative comparison of thermal dose models in normal canine brain. Med Phys 37(10):5313-5321, 2010. e-Pub 2010. PMID: 21089766.
Stafford RJ, Shetty A, Elliott AM, Klumpp SA, McNichols RJ, Gowda A, Hazle JD, Ward JF. Magnetic Resonance Guided, Focal Laser Induced Interstitial Thermal Therapy in a Canine Prostate Model. J Urol 184(4):1514-1520, 2010. e-Pub 2010. PMID: 20727549.
Wang S, Ren W, Liu J, Lahat G, Torres K, Lopez G, Lazar AJ, Hayes-Jordan A, Liu K, Bankson J, Hazle JD, Lev D. TRAIL and doxorubicin combination induces proapoptotic and antiangiogenic effects in soft tissue sarcoma in vivo. Clin Cancer Res 16(9):2591-604, 2010. e-Pub 2010. PMID: 20406839.
Elliott AM, Shetty AM, Wang J, Hazle JD, Stafford RJ. Use of gold nanoshells to constrain and enhance laser thermal therapy of metastatic liver tumors. Int Hyperthermia 26(5):434-40, 2010. e-Pub 2010. PMID: 20597626.
Elliott AM, Schwartz J, Wang J, Shetty AM, Bourgoyne C, O'Neal DP, Hazle JD, Stafford RJ. Quantitative comparison of delta P1 versus optical diffusion approximations for modeling near-infrared gold nanoshell heating. Med Phys 36(4):1351-8, 2009. e-Pub 2009. PMID: 19472642.
Fuentes D, Oden JT, Diller KR, Hazle JD, Elliott A, Shetty A, Stafford RJ. Computational modeling and real-time control of patient-specific laser treatment of cancer. Ann Biomed Eng 37(4):763-82, 2009. e-Pub 2009. PMID: 19148754.
Taylor BA, Hwang KP, Hazle JD, Stafford RJ. Autoregressive moving average modeling for special parameter estimation from a multigradient echo chemical shift acquisition. Med Phys 36(3):753-764, 2009. e-Pub 2009. PMID: 19378736.
Elliott A, Schwartz J, Wang J, Shetty A, Hazle JD, Stafford JR. Analytical solution to heat equation with magnetic resonance experimental verification for nanoshell enhanced thermal therapy. Lasers Surg Med 40(9):660-5, 2008. e-Pub 2008. PMID: 18951423.
Taylor BA, Hwang KP, Elliott AM, Shetty A, Hazle JD, Stafford RJ. Dynamic chemical shift imaging for image-guided thermal therapy: analysis of feasibility and potential. Med Phys 35(2):793-803, 2008. e-Pub 2008. PMID: 18383702.
Diagaradjane P, Shetty A, Wang JC, Elliott AM, Schwartz J, Shentu S, Park HC, Deorukhkar A, Stafford RJ, Cho SH, Tunnell JW, Hazle JD, Krishnan S. Modulation of in vivo tumor radiation response via gold nanoshell-mediated vascular-focused hyperthermia: characterizing an integrated antihypoxic and localized vascular disrupting targeting strategy. Nano Letters 8(5):1492-500, 2008. e-Pub 2008. PMID: 18412402.
Oden JT, Diller KR, Bajaj C, Browne JC, Hazle JD, Babuska I, Bass J, Bidaut L, Demkowicz L, Elliott A, Feng Y, Fuentes D, Prudhomme S, Rylander MN, Stafford RJ, Zhang Y. Dynamic data-driven finite element models for laser treatment of cancer. Numerical Methods for Partial Differential Equations DOI 23/4:904-922, 2007. e-Pub 2007. PMID: 20376194.
Elliott AM, Stafford RJ, Schwarz J, Wang J, Shetty AM, Bourgoyne C, O'Neal P, Hazle JD. Laser-induced thermal response and characterization of nanoparticles for cancer treatment using magnetic resonance thermal imaging. Med Phys 34/7:3102-8, 2007. e-Pub 2007. PMID: 17822017.
Kassouf W, Brown GA, Shetty A, Hazle JD, Stafford RJ, Rosser CJ, Stephens LC, Tinkey PT, Pisters LL. An in vivo orthotopic canine model to evaluate distribution of intraprostatic injectate: implications for gene therapy and drug delivery for prostate cancer. Urology 70(4):822-5, 2007. e-Pub 2007. PMID: 17991580.
Shetty A, Stafford RJ, Elliott A, Kassouf W, Brown GA, Stephens LC, Tinkey PT, Bidaut L, Pisters LL, Hazle JD. Magnetic resonance imaging assessment of a convective therapy delivery paradigm in a canine prostate model. Magnetic Resonance in Imaging 26(6):1672-7, 2007. e-Pub 2007. PMID: 17968888.
Rylander MN, Stafford RJ, Feng Y, Hazle JD, Diller K. Optimizing heat shock protein expression induced by prostate cancer laser therapy through predictive computational models. J Biomed Opt 11/4:041113, 2006. e-Pub 2006. PMID: 16965141.
Ma J, Vu AT, Son JB, Choi H, Hazle JD. Fat-suppressed three-dimensional dual echo Dixon technique for contrast agent enhanced MRI. J Magn Reson Imaging 23/1:36-41, 2006. e-Pub 2006. PMID: 16315212.
Oden JT, Diller KR, Bajaj C, Browne JC, Hazle JD, Babuska I, Bass J, Demkowicz L, Feng Y, Fuentes D, Prudhomme S, Rylander MN, Stafford RJ, Zhang Y. Development of a computational paradigm for laser treatment of cancer. Lecture Notes in Computer Science 3993:530-537, 2006. e-Pub 2006. PMID: 19421426.
Erguvan-Dogan B, Whitman GJ, Nguyen VA, Dryden MJ, Stafford RJ, Hazle JD, McAlee KR, Phelps MJ, Ice MF, Kuerer HM, Middleton LP. Specimen radiography in confirmation of MRI-guided needle localization and surgical excision of breast lesions. AJR Am J Roentgenol 187/2:339-44, 2006. e-Pub 2006. PMID: 16861535.
Ross W, Cody DD, Hazle JD. Design and performance characteristics of a digital flat-panel computed tomography system. Med Phys 33:1888-901, 2006. e-Pub 2006. PMID: 16872096.
Stafford RJ, JD H. Magnetic resonance temperature imaging for focused ultrasound surgery: a review. Top Magn Reson Imaging 17/3:153-63, 2006. e-Pub 2006. PMID: 17414072.
Morin RL, Hazle JD. Magnetic resonance imaging guidance of ablative thermal therapies. J Am Coll Radiol 2(12):1037-9, 2005. e-Pub 2005. PMID: 17411990.
Rivera B, Ahrar K, Kangasniemi MM, Hazle JD, Price RE. Canine transmissible venereal tumor: a large-animal transplantable tumor model. Comp Med 55/4:335-343, 2005. e-Pub 2005. PMID: 16158909.
Bankson JA, Stafford RJ, Hazle JD. Partially parallel imaging with phase-sensitive data: Increased temporal resolution for magnetic resonance temperature imaging. Magn Reson Med 53/3:658-65, 2005. e-Pub 2005. PMID: 15723414.
Hazle JD. The development of technologies for molecular imaging should be driven principally by biological questions to be addressed rather than by simply modifying existing imaging technologies. Med Phys 32/5:1232-3, 2005. e-Pub 2005. PMID: 15984673.
Stafford RJ, Price RE, Diederich CJ, Kangasniemi M, Olsson LE, Hazle JD. Interleaved echo-planar imaging for fast multiplanar magnetic resonance temperature imaging of ultrasound thermal ablation therapy. J Magn Reson Imaging 20/4:706-14, 2004. e-Pub 2004. PMID: 15390144.
McNichols RJ, Kangasniemi M, Gowda A, Bankson JA, Price RE, Hazle JD. Technical developments for cerebral thermal treatment: water-cooled diffusing laser fibre tips and temperature-sensitive MRI using intersecting image planes. Int J Hyperthermia 20/1:45-56, 2004. e-Pub 2004. PMID: 14612313.
Rosser CJ, Tanaka N, Stafford RJ, Price RE, Hazle JD, Tanaka M, Kamat AM, Pister LL. Feasibility to delineate distribution of solution injected intraprostatic using an ex-vivo canine model. Gene Therapy and Molecular Biology 8:509-514, 2004. e-Pub 2004.
Kangasniemi M, McNichols RJ, Bankson JA, Gowda A, Price RE, Hazle JD. Thermal therapy of canine cerebral tumors using a 980 nm diode laser with MR temperature-sensitive imaging feedback. Lasers Surg Med 35/1:41-50, 2004. e-Pub 2004. PMID: 15278927.
Diederich CJ, Stafford RJ, Nau WH, Burdette EC, Price RE, Hazle JD. Transurethral ultrasound applicators with directional heating patterns for prostate thermal therapy: in vivo evaluation using magnetic resonance thermometry. Med Phys 31/2:405-13, 2004. e-Pub 2004. PMID: 15000627.
McNichols RJ, Gowda A, Kangasniemi M, Bankson JA, Price RE, Hazle JD. MR thermometry-based feedback control of laser interstitial thermal therapy at 980 nm. Lasers Surg Med 34/1:48-55, 2004. e-Pub 2004. PMID: 14755424.
Wosik J, L-M X, Nesteruk K, Xue L, Bankson JA, Hazle JD. Superconducting Single and Phased Array Probes for Clinical and Research MRI. IEEE Trans. Applied Supercon 13/2:1050-1055, 2003. e-Pub 2003.
Hirsch LR, Stafford RJ, Bankson JA, Sershen SR, Rivera B, Price RE, Hazle JD, Halas NJ, West JL. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc Natl Acad Sci U S A 100/23:13549-54, 2003. e-Pub 2003. PMID: 14597719.
Kangasniemi M, Stafford RJ, Price RE, Jackson EF, Hazle JD. Dynamic gadolinium uptake in thermally treated canine brain tissue and experimental cerebral tumors. Invest Radiol 38/2:102-7, 2003. e-Pub 2003. PMID: 12544073.
Wyman BT, Stork CL, Smith JP, Price RE, Gavin PR, Tucker RL, Wisner ER, Mattoon JS, Hazle JD. Improved detection of metastases on magnetic resonance images by digital tissue recognition: validation using VX-2 tumor in the rabbit. J Magn Reson Imaging 18/2:232-41, 2003. e-Pub 2003. PMID: 12884337.
Hazle JD, Diederich CJ, Kangasniemi M, Price RE, Olsson LE, Stafford RJ. MRI-guided thermal therapy of transplanted tumors in the canine prostate using a directional transurethral ultrasound applicator. J Magn Reson Imaging 15/4:409-17, 2002. e-Pub 2002. PMID: 11948830.
Hazle JD, Stafford RJ, Price RE. Magnetic resonance imaging-guided focused ultrasound thermal therapy in experimental animal models: correlation of ablation volumes with pathology in rabbit muscle and VX2 tumors. J Magn Reson Imaging 15/2:185-94, 2002. e-Pub 2002. PMID: 11836775.
Kangasniemi M, Diederich CJ, Price RE, Stafford RJ, Schomer DF, Olsson LE, Tyreus PD, Nau WH, Hazle JD. Multiplanar MR temperature-sensitive imaging of cerebral thermal treatment using interstitial ultrasound applicators in a canine model. J Magn Reson Imaging 16/5:522-31, 2002. e-Pub 2002. PMID: 12412028.
Silverman PM, Kalender WA, Hazle JD. Common terminology for single and multislice helical CT. AJR Am J Roentgenol 176/5:1135-6, 2001. e-Pub 2001. PMID: 11312166.
Stafford RJ, JD H, Glover GH. Monitoring of high-intensity focused ultrasound-induced temperature changes in vitro using an interleaved spiral acquisition. Magn Reson Med 43/6:909-12, 2000. e-Pub 2000. PMID: 10861889.
Thompson SK, JD H, Schomer DF, Elekes AA, Johnston DA, Huffman J, Chui CK. Performance analysis of a new semiorthogonal spline wavelet compression algorithm for tonal medical images. Med Phys 27/2:276-88, 2000. e-Pub 2000. PMID: 10718131.
Kallel F, Stafford RJ, Price RE, Righetti R, Ophir J, Hazle JD. The feasibility of elastographic visualization of HIFU-induced thermal lesions in soft tissues. Image-guided high-intensity focused ultrasound. Ultrasound Med Biol 25/4:641-7, 1999. e-Pub 1999. PMID: 10386741.
Righetti R, Kallel F, Stafford RJ, Price RE, Krouskop TA, Hazle JD, Ophir J. Elastographic characterization of HIFU-induced lesions in canine livers. Ultrasound Med Biol 25/7:1099-113, 1999. e-Pub 1999. PMID: 10574342.
Schomer DF, Elekes AA, Hazle JD, Huffman JC, Thompson SK, Chui CK, Murphy WA, Jr. Introduction to wavelet-based compression of medical images. Radiographics 18/2:469-81, 1998. e-Pub 1998. PMID: 9536490.
Reynolds DM, JD H, Johnston DA, Charnsangavej C. Evaluation of helical computed tomography scan parameters for vascular imaging. Med Phys 25/2:176-82, 1998. e-Pub 1998. PMID: 9507477.
Stafford RJ, Kallel F, Price RE, Cromeens DM, Krouskop TA, Hazle JD, Ophir J. Elastographic imaging of thermal lesions in soft tissue: a preliminary study in vitro. Ultrasound Med Biol 24/9:1449-58, 1998. e-Pub 1998. PMID: 10385966.
Wong ET, Jackson EF, Hess KR, Schomer DF, Hazle JD, Kyritsis AP, Jaeckle KA, Yung WK, Levin VA, Leeds NE. Correlation between dynamic MRI and outcome in patients with malignant gliomas. Neurology 50:777-81, 1998. e-Pub 1998. PMID: 9521274.
Price RE, Leeds NE, Hazle JD, Jackson EF, Stephens LC, Ang KK. Magnetic resonance imaging of the central nervous system of the rhesus monkey. Lab Anim Sci 47:304-12, 1997. e-Pub 1997. PMID: 9241635.
Palta JR, Biggs PJ, Hazle JD, Huq MS, Dahl RA, Ochran TG, Soen J, Jr DR, McCullough EC. Intraoperative electron beam radiation therapy: technique, dosimetry, and dose specification: report of task force 48 of the Radiation Therapy Committee, American Association of Physicists in Medicine. Int J Radiat Oncol Biol Phys 33/3:725-46, 1995. e-Pub 1995. PMID: 7558965.
McClain KJ, Zhu Y, Hazle JD. Selection of MR images for automated segmentation. J Magn Reson Imaging 5/5:485-92, 1995. e-Pub 1995. PMID: 8574030.
Hazle JD, Hanson WF. Dosimetry characteristics of four fast neutron generators involved in RTOG interinstitutional clinical trials. Int J Radiat Oncol Biol Phys 30/2:455-7, 1994. e-Pub 1994. PMID: 7928473.
Pettigrew LC, JD H, Gutierrez G, Smith CD, Ogletree ML. Correction of ischaemic brain acidosis with SQ29,548/1-benzylimidazole. Neurol Res 14:335-9, 1992. e-Pub 1992. PMID: 1360630.
Hazle JD, Chu JC, Kennedy P. Quality assurance for intraoperative electron radiotherapy clinical trials: ionization chamber and mailable thermoluminescent dosimeter results. Int J Radiat Oncol Biol Phys 24/3:559-63, 1992. e-Pub 1992. PMID: 1399744.
Hazle JD, Narayana PA, Dunsford HA. In vivo NMR, biochemical, and histologic evaluation of alcohol-induced fatty liver in rat and a comparison with CCl4 hepatotoxicity. Magn Reson Med 19(1):124-35, 1991. e-Pub 1991. PMID: 2046527.
Hazle JD, Hefner L, Nyerick CE, Wilson L, Boyer AL. Detailed dose-response characteristics of a ferrous-sulphate-doped gelatin system for determining radiation absorbed dose distributions by magnetic resonance imaging (Fe MRI). Phys Med Biol 36:1117-25, 1991. e-Pub 1991. PMID: 1924545.
Hazle JD, Kirby TH, Gastorf RJ, Hanson WF. Results of photon absorbed-dose measurements using the AAPM TG-21 protocol for accelerating potentials up to 26 MV. Med Phys 18/6:1234-6, 1991. e-Pub 1991. PMID: 1753909.
Hazle JD, Narayana PA, Dunsford HA. Chronic carbon tetrachloride and phospholipase D hepatotoxicity in rat: in vivo 1H magnetic resonance, total lipid analysis, and histology. Magn Reson Med 15/2:211-228, 1990. e-Pub 1990. PMID: 2392047.
Weirich SD, Cotler HB, Narayana PA, Hazle JD, Jackson EF, Coupe KJ, McDonald CL, Langford LA, Harris JH, Jr. Histopathologic correlation of magnetic resonance imaging signal patterns in a spinal cord injury model. Spine 15/7:630-8, 1990. e-Pub 1990. PMID: 2218708.
Hazle JD, Narayana PA, Kudrle WA. In Vivo Proton NMR Studies of Normal Rat Liver. J Magn Reson 83:595-601, 1989. e-Pub 1989.
Narayana PA, Jackson EF, Hazle JD, Fotedar LK, Kulkarni MV, Flamig DP. In vivo localized proton spectroscopic studies of human gastrocnemius muscle. Magn Reson Med 12:259-60, 1989. e-Pub 1989. PMID: 2559290.
Narayana PA, JD H, Jackson EF, Fotedar LK, Kulkarni MV. In vivo spectroscopic studies of human gastrocnemius muscle at 1.5 T. Magn Reson Med 6:481-5, 1988. e-Pub 1988. PMID: 3226233.
Narayana PA, Jackson EF, Hazle JD, Fotedar LK, Kulkarni MV, Flamig DP. In vivo localized proton spectroscopic studies of human gastrocnemius muscle. Magn Reson Imag 8:151-9, 1988. e-Pub 1988. PMID: 2850438.
Calkins J, Wheeler JS, Keller CI, Colley E, Hazle JD. Comparative Ultraviolet Action Spectra (254-320 nm) of Five "Wild-Type" Eukaryotic Microorganisms and Escherichia coli. Radiat Res 114:307-18, 1988. e-Pub 1988. PMID: 3287425.
Maruyama Y, Beach JL, Hazle JD, Ashtari M, Schroy C, Olson M. Therapeutic Dosimetry for Cf-252 Neutron Brachytherapy of Pelvic Cancer. Int J Radiat Onc Biol Phys 11:927-935, 1985. e-Pub 1985. PMID: 3921501.
Kirby TH, Gastorf RJ, Hanson WF, Berkley LW, Gagnon WF, Hazle JD, Shalek RJ. Electron Central Axis Depth Dose Measurements. Med Phys 12:357-61, 1985. e-Pub 1985. PMID: 3925311.
Hazle JD, Calkins J, Stapp IP. An Integrating System for Measuring the Energy Delivered by a Flashlamp Driven Dye Laser. Phys Med Biol 29:449-454, 1983. e-Pub 1983.
Hannan MA, Zimmer S, Hazle JD. Mechanisms of cisplatin induced cytotoxicity and genotoxicity in yeast. Mutat Res 127:23-30, 1983. e-Pub 1983. PMID: 6374440.
Calkins J, Colley E, Hazle JD. The Use of Caffeine as a Liquid Filter in a Coaxial Flashlamp Pumped Dye Laser. Optics Commun 42:275-277, 1982. e-Pub 1982.
Calkins J, Colley E, Hazle JD, Hannan MA. A Dye Laser Source of Monochromatic UV-B and UV-C Radiation for Biological Action Spectroscopy. Photochem Photobiol 37(6):669-674, 1982. e-Pub 1982. PMID: 6611672.
Chan CH, Li CF, Yang WL, Gao Y, Lee SW, Feng Z, Huang HY, Tsai KKC, Flores LG, Shao Y, Hazle JD, Yu D, Wei W, Sarbassov D, Hung MC, Nakayama KI, Lin HK. The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin, Sensitivity, and Tumorigenesis. Cell 4(151):913-914.
Plachouris D, Eleftheriadis V, Nanos T, Papathansiou N, Sarrut D, Papadimitroulas P, Salvador J, Imperiale A, Visvikis D, Hazle JD, Kagadis GC. A radiomic and dosiomic study concerning predictive absorbed dose value in 177 lutetium-DOTATE therapy based on machine learning regression models. Medical Physics.

Invited Articles

Hazle JD, Mah D, Orton CG. Point/Counterpoint: A professional doctoral degree that does not require dissertation research is an appropriate alternative to a Ph.D. as preparation for a career in medical physics. Med Phys 35(6):2201-2203, 2008. e-Pub 2008.
Stafford RJ, JD H. Magnetic resonance temperature imaging for focused ultrasound surgery: a review. Top Magn Reson Imaging 17/3:153-63, 2006. e-Pub 2006.
Hazle JD, Wilson CR, Hendee WR. Engineering is preferred over physics as an undergraduate preparation for diagnostic and nuclear medical physicists. Med Phys 28:409-11, 2001. e-Pub 2001. PMID: 11339736.
Hazle JD, Thompson SK, Schomer DF, Elekes AA, Liu SJ, Huffman JC, Chui CK. A new spline wavelet based medical image compression algorithm. Proceedings of the Symposium for Computer Assisted Radiology, eds. R.F. Kilcoyner, J.L. Lear, and A.H. Rowberg, Denver, CO:119-124, 1996. e-Pub 1996.
Hazle, JD, Tucker, DM, Schomer, DF. Asynchronous transfer mode communication: Applications in radiology. Proceedings of the ATM Year 96 Conference, San Jose, CA. Telemedicine Section:B1-13, 1996. e-Pub 1996.
Schomer, DF, Thompson, SK, Hazle JD, Elekes, AA, Huffman, JC, Zhong, L, Chui, CK. Application of B-spline wavelets for high-level, high-quality compression of medical image data. Proceedings of the Symposium for Computer Assisted Radiology, eds. R.F. Kilcoyner, J.L. Lear, and A.H. Rowberg, Denver, CO:417-421, 1996. e-Pub 1996.
Schomer DF, Hazle JD, Elekes A, Schmidt WR, Ginsberg LA, Kumar AJ, Leeds NE, Murphy WA. Ultra-High-Ratio Wavelet Compression of Brain MRI: A Pilot Study. Proceedings of Computers and Radiology, Springer-Verlag (Berlin):383-388, 1995. e-Pub 1995.
Hazle JD and Leeds NA. Advances in magnetic resonance neuroimaging. Cancer Bulletin 45/4:304-313, 1993. e-Pub 1993.
Hazle JD, Hefner LF, Baker W, Otte VA, Boyer AL. Measurement of electron beam dose distributions using ferrous sulfate gels and magnetic resonance imaging. Proceedings of the Advanced Radiation Therapy Conference, Tumor Response Monitoring and Treatment planning. A. Breit ed., Munich, Springer-Verlag (Berlin):539-542, 1992. e-Pub 1992.

Manuals, Teaching Aids, Other Teaching Publications

Stelling CB and Hazle JD. MR imaging of the breast (Categorical Course). Radiological Society of North America, 1995.

Editorials

Perkel JM, McConville P, Yuan H, Bourdon M, Hazle J, Contag C, Wang L, Gore J, Phelps P, Goodwill P. Small Animal Imaging: Data that's more than skin deep. SCIENCE - Life Science Technologies 348(6240):1271-1273, 2015.

Abstracts

Jimenez 1 JE, Dai D, Xu G, Zhao R, Li T, Pan T, Wang L, Lin Y, Wang Z, Jaffray D, Hazle JD, Macapinlac HA, Wu J, Lu Y. Lesion-Based Radiomics Signature in Pretherapy 18F-FDG PET Predicts Treatment Response to Ibrutinib in Lymphoma 00(00):10, 2022. e-Pub 2022.
Gatos I, Tsantis S, Zoumpoulis P, Theotokas I, Mihailidis D, Hazle J, Kagadis G. A Fuzzy C-Means Multi-Parametric Segmentation Method for Temporal Stability Area Definition On Shear Wave Elastography Image Sequences. Medical Physics 45(6):2744, 2018. e-Pub 2018.
Gates E, Lin J, Weinberg J, Hamilton J, Prabhu S, Hazle J, Fuller G, Baladandayuthapani V, Fuentes D, Schellingerhout D. Quantitative Prediction of Cellular Proliferation Marker Ki67 Using MR Imaging in Glioma. Medical Physics 45(6):2748, 2018. e-Pub 2018.
Thrower S, Kandala S, Fuentes D, Mathieu K, Stefan W, Kulp A, Hazle J. Comparison of Two Reconstruction Methods for Bound-Nanoparticle Detection Using Superparamagnetic Relaxometry. Medical Physics 45(6):2746, 2018. e-Pub 2018.
Bankson JA, Sandulache VC, Yunyun C, Merritt M, Lai SY, Hazle JD. Tumor Perfusion Correlats with Hyperpolarized Lactate in a Murine Model of Thyroid Cancer. World Molecular Imaging Congress 2012, 2012. e-Pub 2012.
Shetty AM, Schwartz JA, Yung J, McNichols RJ, Price R, Hazle JD, Stafford RJ. Gold nanoshell mediated heating of brain tumors. Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology, 2010. e-Pub 2010.
Shetty AM, Melancon MP, Elliott AM, Huang Q, Wen X, Li C, Hazle JD, Stafford RJ. Perfusion Changes Following EGFR targeted Hollow Gold-Nanoshell Mediated heating of Tumors. ISMRM, 2009. e-Pub 2009.
Elliott AM, Shetty AM, McNichols R, Fuentes D, Hazle JD, Stafford RJ. Magnetic Resonance Guided Laser Thermal Therapy with Finite Element Simulation for Treatment Planning. ISMRM, 2009. e-Pub 2009.
Yung J, Shetty AM, Springer AC, Weinberg J, Hazle JD, Stafford RJ. Comparison of Thermal Dose Models in Canine Brain Using the Dice Similarity Coefficient. ISMRM, 2009. e-Pub 2009.
Stafford RJ, Krafft AJ, McNichols RJ, Gowda A, Bock M, Hazle JD. Localized FFT Phase-Correction Algorithm for Improved Real-Time PRF Shift Thermometry. ISMRM, 2009. e-Pub 2009.
Ai H, Taylor BA, Elliott AM, LePetross H, Hazle JD, Stafford RJ. Initial Evaluation of a Fast Chemical Shift Thermometry Technique in the Breast. ISMRM, 2009. e-Pub 2009.
Taylor BA, Hwang K, Hazle JD, Stafford RJ. Performance of the Steighlitz-McBride Algorithm for Spectral Parameter Estimation from a Rapid Multi-Gradient Echo Acquisition. ISMRM, 2009. e-Pub 2009.
Taylor BA, Elliott AM, Hazle JD, Stafford RJ. Multiparametric Monitoring of Chemical Ablations Using a Rapid Chemical Shift Imaging Technique. ISMRM, 2009. e-Pub 2009.
Taylor BA, Elliott AM, Hazle JD, Stafford RJ. MR-Guided Thermal Ablation in Bone Using a Rapid Chemical Shift Imaging Technique. ISMRM, 2009. e-Pub 2009.
Parmeswaran D, Shetty AM, Wang J, Elliott AM, Schwartz J, Shujun S, Park HC, Deorukhkar A, Stafford RJ, Cho SH, Tunnell JW, Hazle JD, Krishnan S. Enhanced radiation treatment efficacy induced by optically activated gold nanoshell mediated mild hyperthermia: An anti-hypoxic and vascular disruptingeffect. World Molecular Imaging Congress, Nice, France, 2008. e-Pub 2008.
Oden JT, Fuentes D, Diller KR, Hazle JD, Elliott AM, Shetty AM, Stafford RJ. Computational modeling and real-time control of patient-specific laser treatment of cancer. Seventh Interventional MRI Symposium, Baltimore, MD, 2008. e-Pub 2008.
Shetty AM, Elliott AM, Schwartz JA, Wang J, Coss EE, Klumpp S, Gelovani J, Hazle JD, Stafford RJ. Use of DCE-MRI to Evaluate Perfusion Changes in Prostate Tumors Induced by Gold Nanoshells Mediated Heating. World Molecular Imaging Congress, Nice, France, 2008. e-Pub 2008.
Taylor BA, Shetty AM, Elliott AM, Springer AC, Hwang KP, Hazle JD, Stafford RJ. Image-guided thermal ablation in bone using dynamic chemical shift imaging. American Association of Physicists in Medicine 50th Annual Scientific Meeting, Houston, TX, 2008. e-Pub 2008.
Springer A, Shetty A, Am E, Paquet M, Wang J, Schwartz J, Hazle JD, Stafford RJ. Nanoshell-mediated laser induced thermal therapy in an in vivo model. American Association of Physicists in Medicine 50th Annual Scientific Meeting, Houston, TX, 2008. e-Pub 2008.
Stafford RJ, Shetty AM, Elliott AM, Schwartz J, Melancon MP, Li C, Hazle JD. Characterization of gold nanoshells for thermal therapy using MRI. American Association of Physicists in Medicine 50th Annual Scientific Meeting, Houston, TX, 2008. e-Pub 2008.
Stafford RJ, McNichols RJ, Gowda A, Elliott AM, Shetty AM, Hazle JD. A closed-looped guidance of laser induced thermal therapy using MRI. American Association of Physicists in Medicine 50th Annual Meeting, Houston, TX, 2008. e-Pub 2008.
Taylor BA, Hwang KP, Hazle JD, Stafford RJ. A novel approach to multi-parametric dynamic chemical shift imaging. The American Association of Physicists in Medicine 50th Annual Scientific Meeting, Houston, TX, 2008. e-Pub 2008.
Shetty AM, Weinberg J, McNichols R, Gowda A, Yung J, Klumpp S, Uthamanthil R, Borne A, Elliott A, Hazle J, Stafford RJ. Predictive Capabilities of Thermal Damage Model for Real Time MR Monitored Interstitial Laser Treatment in a Canine Brain Model. American Association of Physicists in Medicine 50th Annual Scientific Meeting, Houston, TX, 2008. e-Pub 2008.
Elliott AM, Schwartz J, Wang J, Shetty A, O'Neal DO, Bourgoyne C, Hazle JD, Stafford RJ. Comparison of optical diffusion approximation and delta P1 approximation models for laser fluence in cancer treatment. The American Association of Physicists in Medicine 50th Annual Meeting, Houston, TX, 2008. e-Pub 2008.
Stafford RJ, Bidaut L, Taylor B, Hazle JD. Fast chemical shift imaging technique for image-guided interventions. Computer Assisted Radiology and Surgery 22nd Congress & Exhibition, Barcelona, Spain, 2008. e-Pub 2008.
Marsh R, Terry N, Bankson J, Hazle J. Quantitative in vivo measurement of treatment response n murine tumors using diffusion-weighted magnetic resonance imaging. Proceedings 50th Annual Meeting of the American Association of Physicists in Medicine, Houston, TX, 2008. e-Pub 2008.
Taylor BA, Hwang K, Elliott AM, Shetty AM, Hazle JD, Stafford RJ. A high spatiotemporal chemical shift imaging technique for MR-guided thermal therapy with multi-parametric monitoring capabilities. Proceedings 16th Scientific Meeting, International Society for Magnetic Resonance in Medicine, Toronto, Canada, 2008. e-Pub 2008.
Elliott AM, Shetty AM, Melancon M, Ji X, Taylor BA, Hazle JD, Li C, Stafford RJ. MRTI evaluation of SPIO core gold coated nanoshells for thermal therapy and as T2* contrast agent. Proceedings 16th Scientific Meeting, International Society for Magnetic Resonance in Medicine, Toronto, Canada, 2008. e-Pub 2008.
Stafford RJ, McNichols RJ, Gowda A, Hazle JD. A fast phase-correction algorithm for improved real-time PRF shift thermometry. Proceedings 16th Scientific Meeting, International Society for Magnetic Resonance in Medicine, Toronto, Canada, 2008. e-Pub 2008.
Shetty AM, Price RF, Schwartz J, Uthamanthil R, Wang J, Elliott A, Hazle JD, Stafford RJ. Evaluation of nanoshell mediated tumor ablation with real-time multiplaner MR temperature imaging in a canine brain tumor model. Proceedings 16th Scientific Meeting, International Society for Magnetic Resonance in Medicine, Toronto, Canada, 2008. e-Pub 2008.
Shetty AM, McNichols R, Gowda A, Klumpp S, Elliott A, Borne A, Brammer D, Hazle JD, Stafford RJ. Validation of Percutaneous MRI-Guided Laser Ablation with Real-Time MR Temperature Monitoring in a Canine Prostate Model. Proceedings 16th Scientific Meeting, International Society for Magnetic Resonance in Medicine, Toronto, Canada, 2008. e-Pub 2008.
Elliott AM, Hazle JD, Li C, Stafford RJ. Modeling laser thermal therapy output for nanoshell heating using a natural coordinate system. Proceedings of SPIE 6865, 2008. e-Pub 2008.
Shetty AM, Elliott AM, Schwartz JA, Wang J, Esparza-Coss E, Klumpp S, Taylor B, Hazle JD, Stafford RJ. Use of Gold Nanoshells to Mediate Heating Induced Perfusion Changes in Prostate Tumors. Proceedings of SPIE 6865, 2008. e-Pub 2008.
Elliott AM, Wang J, Shetty AM, Schwartz J, Hazle JD, Stafford RJ. Gold nanoshell thermal confinement of conformal laser thermal therapy in liver metastasis. Proceedings of SPIE 6865, 2008. e-Pub 2008.
Elliott AM, Wang J, Shetty AM, Schwartz J, Hazle JD, Stafford RJ. Nanoscale imaging, sensing, and actuation for biomedical applications V. Proceedings of SPIE 6865, 2008. e-Pub 2008.
Bajaj C, Oden JT, Diller KR, Browne JC, Hazle JD, Babuska I, Bass J, Bidaut L, Demkowicz L, Elliott AM, Feng Y, Fuenties D, Kwon B, Prudhomme S, Stafford RJ, Zhang Y. Using cybr-infrastructure for dynamic data driven laser treatment of cancer. ICCS, Beijing, China, 2007. e-Pub 2007.
Shetty AM, Black PC, Esparza-Coss E, Stafford RJ, Elliott AM, Dinney CP, Hazle JD. Evaluation of variability in bioluminescence measurements in orthotopic bladder tumors with dynamic contrast enhanced MRI (DCE-MRI). ISMRM-ESMRB, Berlin, Germany, 2007. e-Pub 2007.
Marsh R, Bankson JA, Paten N, Stafford RJ, Terry N, Hazle JD. Analysis of high B-value diffusion data may highlight in-vivo cellular changes. ISMRM-ESMRB, Berlin, Germany, 2007. e-Pub 2007.
Elliott AM, Stafford RJ, Shetty AM, Hazle JD, Schwartz J, Wang J, Bourgoyne C, O'Neal DP. MR temperature imaging for development and validation of 3D light propagation models in the presence of gold-silica nanoshells for thermal therapy treatment planning. ISMRM-ESMRB, Berlin, Germany, 2007. e-Pub 2007.
Stafford RJ, Elliott AM, Shetty AM, Wang J, Hazle JD. Nanoparticle enhanced laser induced thermal therapy in liver: Simulation, phantom and ex vivo investigation of feasibility. Joint Annual Meeting of the Society for Thermal Medicine and the World Conference on Interventional Oncology, Washington, DC, 2007. e-Pub 2007.
Marsh RM, Bankson JA, Patel N, Stafford RJ, Terry NHA, Hazle JD. Analysis of high b-value Diffusion Data may Highlight in vivo Cellular Changes. ISMRM Fifteenth Scientific Meeting, Berlin, Germany, 2007. e-Pub 2007.
Elliott AM, Stafford RJ, Shetty AM, Schwartz JA, Wang J, Bourgoyne C, O'Neal PD, Hazle JD. Characterization of laser-induced thermal response of microshells for cancer treatment using magnetic-resonance temperature imaging. SPIE Photonics West, 2007. e-Pub 2007.
Diagaradjane P, Shetty A, Wang J, Schwartz J, Shentu S, Park C, Deorukhar A, Elliott A, Stafford J, Cho S, Tunnell J, Hazle J, Krishnan S. Gold nanoshells mediated hyperthermia enhances the efficacy of radiation therapy. SPIE, 2007. e-Pub 2007.
Shetty AM, Stafford RJ, Esparza-Coss E, Elliott AM, Hazle JD. Growth and initial area under curve correlation data from DCE-MRI for treatment planning and monitoring in Orthotopic tumor models. American Association of Physicists in Medicine, Orlando, Florida, 2006. e-Pub 2006.
Shetty AM, Stafford RJ, Esparza-Coss E, Andtbacka R, Brown G, Black P, Metwalli A, McConkey D, Dinney C, Hazle J. Poster of special merit: High frequency ultrasound to monitor murine orthotopic bladder cancer model: An alternative to magnetic resonance imaging. American Association of Physicists in Medicine, Orlando, FL, 2006. e-Pub 2006.
Shetty A, Stafford RJ, Elliott AM, Kassouf W, Brown GA, Pisters LA, Stephens LC, Tinkey PL, Bidaut L, Hazle JD. Three-dimensional MR tracking of convective therapy distribution in prostate. Society for Magnetic Resonance in Medicine 14th Scientific Meeting, Settle Washington, 2006. e-Pub 2006.
Elliott AM, Stafford RJ, Shetty A, O'Neal P, Bourgoyne C, Hazle JD. Characterization of thermal response of light activated nanoshells in phantom using MR temperature imaging. Society of Magnetic Resonance in Medicine 14th Scientific Meeting, Seattle, Washington, 2006. e-Pub 2006.
Stafford RJ, Shetty A, Elliott AM, Paquet M, Schwartz J, Hazle JD. Magnetic resonance temperature imaging of light activated nanoshell thermal therapy. Proceedings of the Society of Thermal Medicine, Bethesda, MD, 2006. e-Pub 2006.
O'Neal DP, Stafford RJ, Hazle JD. Magnetic resonance temperature imaging of nanoshell photo-thermal therapy, nanobiophotonics and biomedical applications III. Proceedings of SPIE 6095, 2006. e-Pub 2006.
Marsh RM, Bankson JA, Patel N, Hazle JDD, Terry NHA. Magnetic Resonance Imaging, Confocal Microscopy and H&E Staining. Proc ISAC XXIII International Congress, Montreal, CA, 2006. e-Pub 2006.
Tinsley JO, Diller KR, Bajaj C, Browne JC, Hazle JD, Babuska IJ, Demkowicz LF, Feng Y, Fuentes D, Prudehomme S, Rylander MN, Stafford RJ, Zhang Y. Development of a computational paradigm for laser treatment of cancer. International Conference on Computational Science 3:530-537, 2006. e-Pub 2006.
Rylander MN, Feng Y, Diller KR, Stafford RJ, Hazle JD, Bass J. Optimal hyperthermia protocol design through inverse modeling for prostate cancer treatment by controlling HSP expression. Proceedings of the American Society of Mechanical Engineers Summer Bioengineering Conference, Vail, CO:III-76, 2005. e-Pub 2005.
Stafford RJ, O'Neal DP, Hazle JD. Magnetic Resonance temperature imaging of light activated nanoshell thermal therapy. Proceedings of the International Society for Magnetic Resonance in Medicine 13th Scientific Meeting, Miami Beach , FL(31), 2005. e-Pub 2005.
Wendt RE, Bossar B, Bushman MJ, Price RE, Kundra V, Erwin WD, Mack W, Hazle JD. Multiple Mouse Single Photon Emission Computed Tomography. Academy of Molecular Imaging (AMI), 2005. e-Pub 2005.
Lowery A, Neal PO, Loo C, Hirsch LR, Stafford J, Hazle J, Halas NJ, Drezek R, West JL. Photothermal Tumor Therapy with Metallic Nanoshells. World Biomaterials Congress, Sydney, Australia, 2004. e-Pub 2004.
Stafford RJ, McNichols RJ, Gowda A, Price RE, Hazle JD. Evaluation of a prototype MR-guided laser induced thermal therapy device for prostate ablation. Proceedings of the 46th Annual Meeting of the American Association of Physicists in Medicine, Medical Physics 31(6):1817, 2004. e-Pub 2004.
McNichols RJ, Gowda A, Stafford RJ, Price RE, Hazle JD. MRI-guided laser thermal therapy in the prostate: preliminary results. Proceedings of SPIE(5312):94-104, 2004. e-Pub 2004.
Stafford RJ, McNichols RJ, Gowda A, Price RE, Hazle JD. Evaluation of a prototype MR-guided laser induced thermal therapy device for Prostate ablation. Medical Physics 31:1817, 2004. e-Pub 2004.
McNichols JR, Gowda A, Ahrar K, Stafford RJ, Price ER, Hazle JD. Feasibility of percutaneous vertebroplasty iwth MR-guided laser ablation. Proceedings of SPIE(5312):433-444, 2004. e-Pub 2004.
Ice MF, Whitman GJ, Stephens T, Dryden MJ, Zhou J, Hazle JD. MRI Guided Needle Localization of Breast Lesions: Techniques and Initial Experience. Radiological Society of North America, 2003. e-Pub 2003.
Bagrecha N, Stafford RJ, Hazle JD, Jiang T, Zouridakis G. Graphical User Interface for MRI-Guided Ablative Thermal Therapy. Houston Society for Engineering in Medicine and Biology, 2003. e-Pub 2003.
Bagrecha N, Pavlidis I, Tsiamyrtzis P, Stafford RJ, Hazle JD, Zouridakis G. Segmentation & Tracking Algorithm for Visualization During MRI-Guided Ablative Thermal Therapy. Houston Society for Engineering in Medicine and Biology, 2003. e-Pub 2003.
Kangasniemi M, Stafford RJ, Jackson EF, Hazle JD. Dynamic Gd uptake in experimental cerebral tumors and in thermally exposed canine brain tissue. International Society of Magnetic Resonance in Medicine, 2002. e-Pub 2002.
Stafford RJ, and Hazle JD. Fast multi-planar magnetic resonance temperature imaging using multi-shot EPI and spiral acquisitions; sequence comparison and optimization. International Society of Magnetic Resonance in Medicine, 2002. e-Pub 2002.
Bagrecha N, Stafford RJ, Hazle JD and Zouridakis G. Visualization interface for magnetic resonance imaging-guided thermal therapy. Society for Biomedical Imaging, 2002. e-Pub 2002.
Hazle JD, Stafford RJ, Rosser CJ, Price RE, Tonaka M, Tonaka N, Pisters L. MR imaging of gene therapy vector delivery in ex vivo canine prostate. Society of Molecular Imaging, 2002. e-Pub 2002.
McNichols RJ, Gowda A, Kangasniemi M, Bankson JA, Price RE, Hazle JD. Use of the VisualaseTM system for MR-guided intercranial laser therapy. International Society of Magnetic Resonance in Medicine, 2002. e-Pub 2002.
Schomer D, Stafford RJ, Diederich CJ, Price RE, Kangasniemi M, Hazle JD. MR guided ablation of experimental brain tumors using a novel interstitial ultrasound applicator: a pilot study. European Society of Neuroradiology, 2001. e-Pub 2001.
Wright SM, McDougall M, Brown DG and Hazle JD. Arrays of birdcage coils for imaging multiple samples. International Society of Magnetic Resonance in Medicine, Denver, 2001. e-Pub 2001.
Stafford RJ and Hazle JD. Non-linear temperature response in interleaved spiral gradient-echo temperature imaging. International Society of Magnetic Resonance in Medicine, Denver, 2000. e-Pub 2000.
Wyman BT, Stork CL, Price RE, Hazle JD, Gavin PR, Tucker RL, Smith JP. Evaluation of automatic guided specific tissue segmentation using VX-2 tumor in the rabbit. International Society of Magnetic Resonance in Medicine, 2000. e-Pub 2000.
Stafford RJ and Hazle JD. Interleaved gradient-echo planar imaging with fat suppression for MR temperature imaging. International Society of Magnetic Resonance in Medicine, Denver, 2000. e-Pub 2000.
Hazle JD, Stafford RJ, Fenstermacher MJ, Price RE. MR guided focused ultrasound thermal therapy in a canine tumor model. International Society of Magnetic Resonance in Medicine, Denver, 2000. e-Pub 2000.
Schomer DF, Stafford RJ, Diederich CJ, Price RE and Hazle JD. Minimally invasive, image guided, tumor ablation in the brain with a novel intracavitary ultrasound applicator. American Society of Neuroradiology, 2000. e-Pub 2000.
Hill LR, Bernacky BB, Hazle JD, Price RE, Keeling ME. Mass on the head of a juvenile rhesus macaque. Texas-Louisiana Branch American Association for Laboratory Animal Science, 2000. e-Pub 2000.
Moxley DM, Zhou XJ, Silverman PM and Hazle JD. Dosimetry of a new multislice helical CT scanner: Calculated and measured patient doses. Radiological Society of North America, Chicago, 1999. e-Pub 1999.
Hazle JD, Stafford RJ, Price RE. MRI guided focused ultrasound ablation of VX2 tumors in rabbits. International Society of Magnetic Resonance in Medicine, Philadelphia, 1999. e-Pub 1999.
Stafford RJ and Hazle JD. Tissue temperature monitoring using spiral acquisitions. Houston Society for Engineering in Medicine and Biology, Houston, 1999. e-Pub 1999.
Schomer D, Diederich C, Hazle JD, Watts C. A novel thermal ablation technology with potential for the stereotatic treatment of brain tumors. 4th International Stereotatic Radiation and Surgery Congress, Sydney, 1999. e-Pub 1999.
Kallel F, Chiou F, Garra B, Hazle JD, Konofagou E, Krouskop T, Ophir J, Price RE, Righetti R, Stafford RJ. Applications of Elastography. Houston Society for Engineering in Medicine and Biology, Houston, 1999. e-Pub 1999.
Hazle JD, Hsieh E, Stafford RJ, Rosen II. Optimized treatment planning for MR guided focused ultrasound thermal therapy. Houston Society for Engineering in Medicine and Biology, Houston, 1999. e-Pub 1999.
Poonawalla AH, Glover GH, Hazle JD. Spiral imaging for dynamic contrast-enhanced MRI. . Radiological Society of North America, Chicago, 1999. e-Pub 1999.
Stafford RJ, JD H, Glover GH. Monitoring of tissue temperature changes using an interleaved spiral acquisition. . International Society of Magnetic Resonance in Medicine, Philadelphia, 1999. e-Pub 1999.
Hill LR, Bernacky BB, Hazle JD, Price RE. Cephalhematoma in a juvenile rhesus macaque. . Presented at the 27th Annual Association of Primate Veterinarians Workshop. Indianapolis, Indiana, 1999. e-Pub 1999.

Book Chapters

Diller KR, Oden JT, Bajaj C, Browne JC, Hazle JD, Babuska I, Bass J, Bidaut L, Demkowicz L, Elliott A, Feng Y, Fuentes D, Goswami S, Hawkins A, Khoshnevis S, Kwon B, Prudhomme S, Stafford RJ. Computational Infrastructure for the Real-Time Patient-Specific Treatment of Cancer. In: In: Advances in Numerical Heat Transfer. Illustrated. CRC Press, 2009.
Stafford RJ and Hazle JD. Fundamentals Principles of Magnetic Resonance Temperature Imaging. In: MRI-guided focused ultrasound surgery. Informa Healthcare, 25-42, 2007.
Oden JT, Diller KR, Bajaj C, Browne JC, Hazle JD, Babuska I, Bass J, Demkowicz L, Feng Y, Fuentes D, Prudhomme S, Rylander MN, Stafford RJ, Zhang Y. Development of a computational paradigm for laser treatment of cancer. In: Lecture Notes in Computer Science. Springer-Verlag, 530-7, 2006.
and Jackson HJ, EF. Magnetic Resonance Imaging and PACS. In: Practical Digital Imaging and PACS. Medical Physics Publishing, 67-89, 1999.
Hazle JD. State-Of-The-Art in Medical Imaging. In: Imaging in Radiation Therapy. Medical Physics Publishing, 1-11, 1998.
Hazle JD. MRI primary magnets. In: Magnetic resonance imaging, physical and biological principles. 2nd. C.V. Mosby Company, 128-143, 1998.
Hazle JD. MRI secondary magnets. In: Magnetic resonance imaging physical and biological principles. 2nd. C.V. Mosby Company, 144-158, 1998.
Fuentes D, Oden JT, Diller KR, Yung JP, Feng Y, Hazle JD, Shetty A, Stafford RJ. Computational and MR-guided patient-specific laser induced thermal therapy of cancer. In: Data Driven Application Systems. Springer.

Books (edited and written)

Hazle JD and Boyer AL. Imaging in Radiation Therapy. Medical Physics Publishing, 1998.

Letters to the Editor

Hazle JD. Editorial comment, A comparison of conventional mammographic magnification, ultra-high magnification, and industrial magnification radiography in the radiographic detection of microcalcifications with core biopsies of the breast. British Journal of Radiology 70/839: 1099-1103, 1997.

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Selected Presentations & Talks

Local Presentations

2016. Radiomics - Garbage In, Garbage Out. Conference. Radiomics - Garbage In, Garbage Out. Houston, TX, US.
2013. CABIR and Other Imaging Resources for Collaboration. Conference. CABIR and Other Imaging Resources for Collaboration. Houston, TX, US.
2012. Small Animal Imaging Facility an update on resources and science. Conference. Small Animal Imaging Facility an update on resources and science. Houston, TX, US.
2010. MRI Guided Interventions & Surgery. Conference. MRI Guided Interventions & Surgery. Houston, TX, US.
2009. Research in the Small Animal Imaging Facility. Conference. Research in the Small Animal Imaging Facility. Houston, TX, US.
2005. Organizing Committee. Conference. Organizing Committee. Houston, TX, US.
2004. Small Animal Imaging. Conference. Small Animal Imaging. Houston, TX, US.
2001. MR Guided Focused Ultrasound: How it works. Conference. MR Guided Focused Ultrasound: How it works. Houston, TX, US.
1999. Animal Models for Technology Development. Conference. Animal Models for Technology Development. Houston, TX, US.

Regional Presentations

2007. Imaging Technologies for Thermal Therapy. Conference. Imaging Technologies for Thermal Therapy. The Woodlands, TX, US.

National Presentations

2018. Magnetic Relaxometry for Early Cancer Detection. Conference. Imaging in 2020 Conference. Jackson Hole, WY, US.
2017. Hepatocellular Carcinoma (HCC) Response to Transcatheter Arterial Chemoembolization (TACE) and Its Correlation with HCC Tumor Volumes. Conference. Radiological Society of North America. Chicago, IL, US.
2017. Molecularly targeted micellar magnetic probes for in-vivo early cancer detection using superparamagnetic relaxometry. Conference. World Molecular Imaging Congress 2017. Philadelphia, PA, US.
2017. Image reconstruction in superparamagnetic relaxometry: a deep learning approach. Conference. World Molecular Imaging Congress 2017. Philadelphia, PA, US.
2007. An Overview of Technologies in Oncologic Imaging. Conference. Radiological Society of North America. Chicago, IL, US.
2005. Radio interview on medical applications of nanoshell technologies, nationally syndicated show Science and Society hosted by Dr. David Lemberg, Transcripts available at http://www.worldtalkradio.com/archive.asp?aid=4795. Conference. Science and Society hosted by Dr. David Lemberg, US.
2004. Magnetic resonance thermal imaging applications in bioheat research, workshop on Transport Processes in Biological Systems. Conference. NSF and NIBIB. Bethesda, MD, US.
2004. Light activated nanoshell thermal therapy for cancer. This talk was included in the opening session with Drs. Richard Smalley (1996 Nobel Prize) and Ferid Murad (1998 Nobel Prize). Conference. Alliance for NanoHealth Workshop. Houston, TX, US.
2002. Partially parallel imaging of phase sensitive data: Increased temporal resolution for MR thermography. Conference. International Society of Magnetic Resonance in Medicine. Honolulu, HI, US.
2002. The Role of Biological Imaging in Radiation Oncology. Conference. NCI workshop. Rockville, MD, US.
2002. A Novel Intravascular Quarter-Wave Length Resonator for Imaging Atherosclerosis. Conference. International Society of Magnetic Resonance in Medicine. Honolulu, HI, US.
2002. Dynamic updating of spiral interleaves for magnetic resonance temperature imaging. Conference. International Society of Magnetic Resonance in Medicine. Honolulu, HI, US.
2002. Approaches to thermal imaging with magnetic resonance. Conference. Radiation Research/North American Hyperthermia Society Annual Meeting. Reno, NV, US.
2002. MR guided focused ultrasound thermal therapy in experimental large animal models. Conference. International Society of Magnetic Resonance in Medicine workshop on MRI Guided Focused Ultrasound. Boston, MA, US.
2001. State-of-the-art in fast MR temperature imaging. Conference. joint NIHDOE workshop on In vivo Thermography. Bethesda, MD, US.
2001. Approaches to fast MR temperature imaging. Conference. American Association of Physicists in Medicine. Salt Lake City, UT, US.
2001. State-of-the-art in Medical Imaging: a post-Y2K update. Conference. Radiological Society of North America. Chicago, IL, US.
1999. MR Guided Focused Ultrasound Ablation in an Animal Model. Conference. International Meeting of the Engineering in Medicine and Biology Society. Atlanta, GA, US.
1999. A history of imaging physics at MD Anderson Cancer Center, Southwest Chapter. Conference. American Association of Physicists in Medicine. Houston, TX, US.
1999. State-of-the-art in Medical Imaging. Conference. Radiological Society of North America. Chicago, IL, US.
1997. Demonstration of a world-wide-web-based viewer for DICOM formatted medical images. (Honorable Mention). Conference. Society of Nuclear Medicine. San Antonio, TX, US.
1996. Long Distance Demonstration of a Context Sensitive Image Viewer with ATM Telecommunications. (Cum Laude award). Conference. Radiological Society of North America. Chicago, IL, US.
1995. Use of the Discrete Wavelet Transform to Perform High-Level Data Compression for Applications in Teleradiology. Conference. Radiological Society of North America 81st Annual Meeting. Chicago, IL, US.
1995. Acquisition and processing techniques for dynamic MRI. (Certificate of Merit). Conference. Radiological Society of North America. Chicago, IL, US.

International Presentations

2012. Small Animal Models for Imaging Brain Cancer. Conference. International Society for Magnetic Resonance in Medicine. Melbourne, AU.
2010. Magnetic Resonance Guided Thermal Therapy. Conference. Magnetic Resonance Guided Thermal Therapy. Taipei, TW.
2010. The Evolving Process of Educating and Certifying Medical Physicists in the US. Conference. The Evolving Process of Educating and Certifying Medical Physicists in the US. Taipei, TW.
2003. Volumetric CT in small animals, Molecular Imaging Symposium: converging biology and imaging. Conference. Robarts Research Institute. London, CA.

Formal Peers

2004. Magnetic resonance and the Nobel Prize, Keck Center for Computational Biology. Invited. Houston, TX, US.
2003. Recent advances in fast MR temperature imaging. Invited. Boston, MA, US.
2002. Magnetic resonance imaging guided thermal therapy. Invited. Toronto, CA.
2001. MR guided thermal therapies. Invited. Cleveland, OH, US.
2001. Ultra-fast MR imaging for thermal therapy guidance. Invited. Houston, TX, US.

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Grant & Contract Support

Date:	2024 - 2026
Title:	Cancer Center Support (CORE) Grant: Small Animal Imaging Facility
Funding Source:	NIH/NCI
Role:	Director
ID:	4P30CA016672-48

Date:	2022 - 2027
Title:	Interdisciplinary Translational Pre/Postdoctoral Program in Cancer Nanotechnology
Funding Source:	NIH/NCI
Role:	Mentor
ID:	5T32CA196561-08

Date:	2022 - 2027
Title:	Interdisciplinary Translational Pre/Postdoctoral Program in Cancer Nanotechnology
Funding Source:	NIH/NCI
Role:	Mentor
ID:	2T32CA196561-06

Date:	2022 - 2027
Title:	Radioimmunogenomic analysis of indeterminant pulmonary nodules for precision immunoprevention of lung cancer
Funding Source:	NIH/NCI
Role:	Other Significant Contributor
ID:	1R01CA269475-01

Date:	2022 - 2026
Title:	Radioimmunogenomic analysis of indeterminant pulmonary nodules for precision immunoprevention of lung cancer
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Other Significant Contributor
ID:	RP220374

Date:	2021 - 2026
Title:	Radioimmunogenomic Habitat Phenotypes to Predict Efficacy of Neoadjuvant Immunotherapies in Non-Small Cell Lung Cancer
Funding Source:	NIH/NCI
Role:	Other Significant Contributor
ID:	5R01CA262425-03

Date:	2021 - 2023
Title:	Photon Counting Detector Micro CT
Funding Source:	NIH/OD
Role:	Advisory Committee Member
ID:	1S10OD028621-01A1

Date:	2021 - 2026
Title:	Sequential targeted therapy and real time monitoring of treatment response by PET imaging in adult and pediatric soft tissue sarcomas
Funding Source:	NIH/NCI
Role:	Consultant
ID:	1R01CA258535-01

Date:	2020 - 2025
Title:	UPWARDS Training Program (Underrepresented Minorities Working Towards Research Diversity in Science)
Funding Source:	NIH/NCI
Role:	Program Faculty
ID:	5R25CA240137-05

Date:	2020 - 2023
Title:	Superparamagnetic relaxometry detection of lymph node involvement in HER2+ breast cancer
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Collaborator
ID:	RP200353

Date:	2019 - 2024
Title:	Image Guided Cancer Therapy Training Program
Funding Source:	NIH/NHLBI
Role:	Mentor
ID:	1T32CA244131-01

Date:	2019 - 2026
Title:	Cancer Center Support Grant - Small Animal Imaging Facility
Funding Source:	NIH/NCI
Role:	Core Director
ID:	5P30CA016672-48

Date:	2019 - 2020
Title:	Superparamagnetic relaxometry detection of metastatic breast cancer
Funding Source:	NIH/NCI
Role:	CO-I
ID:	1R21CA240572-01

Date:	2019 - 2024
Title:	UPWARDS Training Program (Underrepresented Minorities Working Towards Research Diversity in Science)
Funding Source:	NIH/NCI
Role:	Program Faculty
ID:	1R25CA240137-01

Date:	2018 - 2023
Title:	Superparamagnetic Relaxometry Detection of Ovarian Cancer
Funding Source:	NIH/NIBIB
Role:	CO-I
ID:	1R01EB027477-01

Date:	2018 - 2022
Title:	A data driven superparamagnetic relaxometry signal model for ovarian cancer detection
Funding Source:	National Science Foundation (NSF)
Role:	CO-I

Date:	2018 - 2021
Title:	Imaging based predictions of glioma pathology and its impact on successful surgery
Funding Source:	NIH/NCI
Role:	Mentor
ID:	1F31CA236338-01

Date:	2018 - 2023
Title:	Fellow and Resident Radiation Oncology Intensive Training in Imaging and Informatics to Empower Research Careers (FRONTI2ER)
Funding Source:	NIH/NIBIB
Role:	Executive Committee Member
ID:	5R25EB025787-05

Date:	2018 - 2023
Title:	Standardized Quantitative Imaging Biomarkers for Co-Clinical Trials
Funding Source:	NIH/NCI
Role:	PI
ID:	1U24CA220280-01A1

Date:	2018 - 2023
Title:	Imaging Pathology Correlations in Glioma
Funding Source:	NIH/NIBIB
Role:	Sponsor
ID:	1F31EB026307-01

Date:	2018 - 2021
Title:	Quantitative Science at MD Anderson Cancer Center
Funding Source:	National Science Foundation (NSF)
Role:	Mentor

Date:	2018 - 2022
Title:	A Phase II Integrative Study of Image Guided Esophageal Cancer Therapy (INSIGHT)
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	Collaborator
ID:	RP180183

Date:	2017 - 2019
Title:	NO TITLE PROVIDED
Funding Source:	NIH/NCI
Role:	CO-I
ID:	1R21CA222999-01

Date:	2017 - 2019
Title:	Mathematical modeling of treatment response of hepatocellular carcinoma
Funding Source:	NIH/NCI
Role:	Other Significant Contributer
ID:	1R21CA215577-01A1

Date:	2017 - 2020
Title:	Signal Processing and Source Imaging Methods for Superparamagnetic Relaxometry
Funding Source:	University of California
Role:	PI

Date:	2017 - 2022
Title:	Modeling and constrained reconstruction strategies for imaging tumor metabolism with hyperpolarized pyruvate
Funding Source:	NIH/NCI
Role:	CO-I
ID:	1R01CA208041-01A1

Date:	2017 - 2022
Title:	Standardized Quantitative Imaging Biomarkers for Co-Clinical Trials
Funding Source:	NIH/NCI
Role:	Co-PI
ID:	1U24CA220280-01

Date:	2017 - 2019
Title:	Superparamagnetic Relaxometry for Early Detection of Ovarian Cancer
Funding Source:	Sister Institution Network Fund
Role:	CO-I

Date:	2017 - 2019
Title:	Mathematical modeling of drug response of hepatocellular carcinoma to targeted therapy
Funding Source:	NIH/NCI
Role:	Other Significant Contributer
ID:	1R21CA215577-01

Date:	2017 - 2025
Title:	Multi-Site Development & Evaluation of a Quantitative 3D Hyperpolarized C-13 MRI Clinical Prostate Cancer Exam
Funding Source:	NIH/NCI
Role:	Co-I
ID:	5R01CA211150-05

Date:	2016 - 2020
Title:	Developing Predictive Models of Treatment Response in HCC
Funding Source:	UTMDACC Institutional Research Grant
Role:	Collaborator

Date:	2016 - 2018
Title:	A sparse reconstruction algorithm for superparamagnetic relaxometry
Funding Source:	NIH/NCI
Role:	Mentor
ID:	5F31CA210434-02

Date:	2016 - 2021
Title:	Modeling and Constrained Reconstruction Strategies for Imaging Tumor Metabolism with Hyperpolarized Pyruvate
Funding Source:	NIH/NCI
Role:	CO-I
ID:	1R01CA208041-01

Date:	2016 - 2021
Title:	Quantitative Breast MRI Radiomics for Precision Medicine
Funding Source:	NIH/NCI
Role:	CO-I

Date:	2015 - 2020
Title:	Imaging and Molecular Correlates of Progression in Cystic Neoplasms of the Pancreas
Funding Source:	NIH/NCI
Role:	Other Significant Contributor
ID:	5U01CA196403-05

Date:	2015 - 2021
Title:	Advancing Magnetic Relaxometry
Funding Source:	Imagion
Role:	PI
ID:	No Assigned #

Date:	2015 - 2020
Title:	Robust MR Imaging Informatics for a Randomized Proton vs. Photon Trial
Funding Source:	American Cancer Society (ACS)
Role:	Mentor
ID:	Mentor Research Scholar Grant

Date:	2015 - 2020
Title:	Magnetic Detection Technology
Funding Source:	Apache Corporation
Role:	PI
ID:	No Assigned #

Date:	2015 - 2020
Title:	Physical Dynamics of the Tumor-Host Interaction-Project 3
Funding Source:	Rice/NIH
Role:	CO-I

Date:	2015 - 2018
Title:	TMC REACH Hub
Funding Source:	Rice/NIH
Role:	Principal Investigator-MDACC

Date:	2014 - 2015
Title:	Early Detection of Ovarian Cancer through Nanomagnetic Relaxometry
Funding Source:	MDACC/Blanton-Davis Ovarian Cancer Research Program Sprint for Life Research Award
Role:	CO-I

Date:	2014 - 2016
Title:	P5: Novel MRI and MRS Methods for Imaging Cancer Metabolism
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	CO-I
ID:	RP140021-P05

Date:	2013 - 2015
Title:	Cancer Center Support Grant Development Funds: New Technology Implementation in Shared Resources, NIH/NCI,
Funding Source:	NIH/NCI
Role:	PI
ID:	P30 CA016672-38

Date:	2012 - 2013
Title:	Visual Sonics, Vevo LAZR high resolution in vivo micro-imaging system
Funding Source:	NIH/NCI
Role:	PI
ID:	1 S10 OD 010 403 01

Date:	2010 - 2013
Title:	Prospective 3D Treatment Planning for MR-guided Laser Induced Thermal Therapy Procedures
Funding Source:	NIH/NIBIB
Role:	CO-I
ID:	5R21EB010196-02

Date:	2010 - 2014
Title:	Fast Imaging Methods for Hyperpolarized Nuclei
Funding Source:	Cancer Prevention & Research Institute of Texas (CPRIT)
Role:	CO-I
ID:	RP101243-P05

Date:	2008 - 2019
Title:	Cancer Center Support Grant-Small Animal Imaging Facility
Funding Source:	NIH/NCI
Role:	Core Director
ID:	5P30CA016672-42

Date:	2007 - 2013
Title:	Experimental Cancer Imaging Research Program (ECIRP)
Funding Source:	NIH/NCI
Role:	PI
ID:	5U24CA126577-05

Date:	2006 - 2013
Title:	Medical Physics Training Grant for Image-Guided Therapy Research
Funding Source:	NIH/NCI
Role:	Mentor
ID:	5 T32 CA119930

Date:	2006 - 2007
Title:	Interactive Image Guided Thermal Therapy for Localized Prostate Cancer
Funding Source:	NIH
Role:	CO-I
ID:	R44 AG19276

Date:	2006 - 2007
Title:	Interactive Image-Guided Closed Loop Thermal Therapy System
Funding Source:	NIH/NCI
Role:	CO-I
ID:	R44 CA079282

Date:	2005 - 2008
Title:	Collaborative Research: TMRP-Dynamic Data-Driven System for Laser Treatment of Cancer
Funding Source:	National Science Foundation (NSF)
Role:	Subcontract PI
ID:	CNS-0540063

Date:	2005 - 2007
Title:	Percutaneous Vertebroplasty with MR-Guided Laser Ablation
Funding Source:	NIH/NCI
Role:	CO-I
ID:	R44 CA101573-02

Date:	2004 - 2007
Title:	Chemoprevention of murine urinary bladder carcinogenesis
Funding Source:	NIH/NCI
Role:	Collaborator
ID:	R03CA109917

Date:	2004 - 2006
Title:	Interactive Image Guided Thermal Therapy for Localized Prostate Cancer
Funding Source:	NIH SBIR through BioTex, Inc.,
Role:	CO-I

Date:	2003 - 2008
Title:	Two-Year Grant Support of Clinical Residencies in Imaging
Funding Source:	AAPM
Role:	PI

Date:	2003 - 2004
Title:	Small Animal Imaging Research Resource
Funding Source:	NIH/NCI
Role:	Resource Director
ID:	P30 CA016672-28

Date:	2003 - 2004
Title:	Nanoshells for biologically targeted thermally ablative therapy
Funding Source:	NIBIB through Nanospectra, Inc
Role:	Co-PI

Date:	2002 - 2007
Title:	Small Animal Imaging Facility
Funding Source:	NIH/NCI
Role:	Resource Director
ID:	5P30CA

Date:	2002 - 2003
Title:	Small Animal Imaging Research Resource
Funding Source:	NIH/NCI
Role:	Resource Director
ID:	P30 CA016672-27

Date:	2001 - 2003
Title:	MR Imaging of Experimental Bladder Cancer
Funding Source:	American Cancer Society (ACS)
Role:	Project Leader
ID:	P50 CA91846 DRP5

Date:	2001 - 2003
Title:	Interactive Image Guided Closed Loop Thermal Therapy
Funding Source:	NIH SBIR grant through BioTex, Inc
Role:	CO-I

Date:	2001 - 2002
Title:	Small Animal MR Imaging System
Funding Source:	NCRR
Role:	PI
ID:	S10 RR15724

CV information above last modified May 23, 2025

John D. Hazle, Ph.D., FAAPM, FACR, FAIMBE

About Dr. John D. Hazle

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Degree-Granting Education

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Help #EndCancer

John D. Hazle, Ph.D., FAAPM, FACR, FAIMBE

About Dr. John D. Hazle

Present Title & Affiliation

Primary Appointment

Education & Training

Degree-Granting Education

Board Certifications

Experience & Service

Institutional Committee Activities

Honors & Awards

Professional Memberships

Selected Publications

Peer-Reviewed Articles

Invited Articles

Manuals, Teaching Aids, Other Teaching Publications

Other Articles

Editorials

Abstracts

Book Chapters

Books (edited and written)

Letters to the Editor

Selected Presentations & Talks

Local Presentations

Regional Presentations

National Presentations

International Presentations

Formal Peers

Grant & Contract Support

Patient Reviews

Request an Appointment

Related Links

Care Centers and Clinics

Departments and Divisions

Labs

Clinical Trials

Help #EndCancer

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