
John M. Slopis, M. D.
Department of Neuro-Oncology, Division of Cancer Medicine
Present Title & Affiliation
Primary Appointment
Professor, Department of Neuro-Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Medical Director, Neurofibromatosis Program, Department of Neuro-Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Associate Professor, Department of Neurology, The University of Texas Medical School at Houston, Houston, TX
Education & Training
Degree-Granting Education
1983 | The University of Texas Medical School, Houston, TX, USA, MD, Medicine |
1979 | University of St. Thomas, Houston, TX, USA, BA, Chemistry |
Board Certifications
1994 | American Board of Psychiatry and Neurology with Special Qualifications in Child Neurology |
Experience & Service
Institutional Committee Activities
Member, The Neurologic Death Task Force of the ICU Best Practice Committee, 2011 - Present
Honors & Awards
2016 | Honorary Chairman at Dining Out in Dallas, Texas Neurofibromatosis Foundation |
2010 - Present | America's Top Pediatrician, Consumers' Research Council of America |
Selected Publications
Peer-Reviewed Articles
- Cabrera TB, Wang W, Yedururi S, Slopis JM, Steiner RE, Rytting ME, Cuglievan B.. Coincidental Expression of Classic Hodgkin Lymphoma and Neurofibromatosis Type I and Literature Review. J Pediatr Hematol Oncol 43(4):e535-e538, 2021. PMID: 32366782.
- Koczkowska M, Callens T, Chen Y, Gomes A, Hicks AD, Sharp A, Johns E, Uhas KA, Armstrong L, Bosanko KA, Babovic-Vuksanovic D, Baker L, Basel DG, Bengala M, Bennett JT, Chambers C, Clarkson LK, Clementi M, Cortés FM, Cunningham M, D'Agostino MD, Delatycki MB, Digilio MC, Dosa L, Esposito S, Fox S, Freckmann ML, Fauth C, Giugliano T, Giustini S, Goetsch A, Goldberg Y, Greenwood RS, Griffis C, Gripp KW, Gupta P, Haan E, Hachen RK, Haygarth TL, Hernández-Chico C, Hodge K, Hopkin RJ, Hudgins L, Janssens S, Keller K, Kelly-Mancuso G, Kochhar A, Korf BR, Lewis AM, Liebelt J, Lichty A, Listernick RH, Lyons MJ, Maystadt I, Martinez Ojeda M, McDougall C, McGregor LK, Melis D, Mendelsohn N, Nowaczyk MJM, Ortenberg J, Panzer K, Pappas JG, Pierpont ME, Piluso G, Pinna V, Pivnick EK, Pond DA, Powell CM, Rogers C, Ruhrman Shahar N, Rutledge SL, Saletti V, Sandaradura SA, Santoro C, Schatz UA, Schreiber A, Scott DA, Sellars EA, Sheffer R, Siqveland E, Slopis JM, Smith R, Spalice A, Stockton DW, Streff H, Theos A, Tomlinson GE, Tran G, Trapane PL, Trevisson E, Ullrich NJ, Van den Ende J, Schrier Vergano SA, Wallace SE, Wangler MF, Weaver DD, Yohay KH, Zackai E, Zonana J, Zurcher V, Claes KBM, Eoli M, Martin Y, Wimmer K, De Luca A, Legius E, Messiaen LM.. Clinical spectrum of individuals with pathogenic NF1 missense variants affecting p.Met1149, p.Arg1276, and p.Lys1423: genotype-phenotype study in neurofibromatosis type 1. Hum Mutat 41(1):299-315, 2020. e-Pub 2019. PMID: 31595648.
- Mahadeo KM, Khazal SJ, Abdel-Azim H, Fitzgerald JC, Taraseviciute A, Bollard CM, Tewari P, Duncan C, Traube C, McCall D, Steiner ME, Cheifetz IM, Lehmann LE, Mejia R, Slopis JM, Bajwa R, Kebriaei P, Martin PL, Moffet J, McArthur J, Petropoulos D, O'Hanlon Curry J, Featherston S, Foglesong J, Shoberu B, Gulbis A, Mireles ME, Hafemeister L, Nguyen C, Kapoor N, Rezvani K, Neelapu SS, Shpall EJ.. Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. Management guidelines for paediatric patients receiving chimeric antigen receptor T cell therapy. Nature Reviews, Clinical Oncology 16(1):45-63, 2019. PMID: 30082906.
- D'Angelo F, Ceccarelli M, Tala, Garofano L, Zhang J, Frattini V, Caruso FP, Lewis G, Alfaro KD, Bauchet L, Berzero G, Cachia D, Cangiano M, Capelle L, de Groot J, DiMeco F, Ducray F, Farah W, Finocchiaro G, Goutagny S, Kamiya-Matsuoka C, Lavarino C, Loiseau H, Lorgis V, Marras CE, McCutcheon I, Nam DH, Ronchi S, Saletti V, Seizeur R, Slopis J, Suñol M, Vandenbos F, Varlet P, Vidaud D, Watts C, Tabar V, Reuss DE, Kim SK, Meyronet D, Mokhtari K, Salvador H, Bhat KP, Eoli M, Sanson M, Lasorella A, Iavarone A.. The molecular landscape of glioma in patients with Neurofibromatosis 1. Nature Medicine 25(1):176-187, 2019. e-Pub 2018. PMID: 30531922.
- Young ED, Ingram D, Metcalf-Doetsch W, Khan D, Al Sannaa G, Le Loarer F, Lazar AJF, Slopis J, Torres KE, Lev D, Pollock RE, McCutcheon IE.. Clinicopathological variables of sporadic schwannomas of peripheral nerve in 291 patients and expression of biologically relevant markers. Journal of Neurosurgery 129(3):805-814, 2018. e-Pub 2017. PMID: 28885122.
- Koenig MK1, Bell CS1, Hebert AA1,2, Roberson J, Samuels JA, Slopis JM, Tate P, Northrup H;. Efficacy and Safety of Topical Rapamycin in Patients With Facial Angiofibromas Secondary to Tuberous Sclerosis Complex: The TREATMENT Randomized Clinical Trial. JAMA Dermatology 154(7):773-780, 2018. PMID: 29800048.
- Jittapiromsak N, Hou P, Liu HL, Sun J, Slopis JM, Chi TL.. Prognostic Role of Conventional and Dynamic Contrast-Enhanced MRI in Optic Pathway Glioma in Journal of Neuroimaging. Journal of Neuroimaging 27(6):594-601, 2017. e-Pub 2017. PMID: 28524459.
- Rosnau K, Hashmi SS, Northrup H, Slopis J, Noblin S, Ashfaq M. Knowledge and Self-Esteem of Individuals with Neurofibromatosis Type 1 (NF1). J Genet Couns. e-Pub 2016. PMID: 27815662.
- Ostrow KL, Bergner AL, Blakeley J, Evans DG, Ferner R, Friedman JM, Harris GJ, Jordan JT, Korf B, Langmead S, Leschziner G, Mautner V, Merker VL, Papi L, Plotkin SR, Slopis JM, Smith MJ, Stemmer-Rachamimov A, Yohay K, Belzberg AJ. Creation of an international registry to support discovery in schwannomatosis. Am J Med Genet A. e-Pub 2016. PMID: 27759912.
- Watson KL, Al Sannaa GA, Kivlin CM, Ingram DR, Landers SM, Roland CL, Cormier JN, Hunt KK, Feig BW, Ashleigh Guadagnolo B, Bishop AJ, Wang WL, Slopis JM, McCutcheon IE, Lazar AJ, Torres KE. Patterns of recurrence and survival in sporadic, neurofibromatosis Type 1-associated, and radiation-associated malignant peripheral nerve sheath tumors. J Neurosurg:1-11. e-Pub 2016. PMID: 27035165.
- Ghali MGZ, Srinivasan VM, Jea A, Slopis JM, McCutcheon IE.. Neurofibromas of the Phrenic Nerve: A Case Report and Review of the Literature. World Neurosurg 88:237-242, 2016. e-Pub 2015. PMID: 26746336.
- Kivlin CM, Watson KL, Al Sannaa GA, Belousov R, Ingram DR, Huang KL, May CD, Bolshakov S, Landers SM, Kalam AA, Slopis JM, McCutcheon IE, Pollock RE, Lev D, Lazar AJ, Torres KE. Poly (ADP) Ribose Polymerase Inhibition: A Potential Treatment of Malignant Peripheral Nerve Sheath Tumor. Cancer Biol Ther 17(2):0, 2016. e-Pub 2015. PMID: 26650448.
- Subbiah V, Bupathi M, Kato S, Livingston A, Slopis J, Anderson PM, Hong DS. Clinical next-generation sequencing reveals aggressive cancer biology in adolescent and young adult patients. Oncoscience 2(7):646-58, 2015. e-Pub 2015. PMID: 26328274.
- Debnam JM, Mahfouz YM, Ketonen L, Slopis JM, McCutcheon IE, Guha-Thakurta N. Multidetector CT with 3-dimensional Volume Rendering in the Evaluation of the Spine in Patients with Neurofibromatosis Type 1: A Retrospective Review of 73 Patients. Scoliosis 9:15:1-10. e-Pub 2014.
- Khiewvan B, Macapinlac HA, Lev D, McCutcheon IE, Slopis JM, Al Sannaa G, Wei W, Chuang HH. The value of ¹ F-FDG PET/CT in the management of malignant peripheral nerve sheath tumors. Eur J Nucl Med Mol Imaging 41(9):1756-66, 2014. e-Pub 2014. PMID: 24699907.
- Theeler BJ, Ellezam B, Yust-Katz S, Slopis JM, Loghin ME, de Groot JF. Prolonged survival in adult neurofibromatosis type I patients with recurrent high-grade gliomas treated with bevacizumab. J Neurol. e-Pub 2014. PMID: 24859329.
- Piotrowski A, Xie J, Liu YF, Poplawski AB, Gomes AR, Madanecki P, Fu C, Crowley MR, Crossman DK, Armstrong L, Babovic-Vuksanovic D, Bergner A, Blakeley JO, Blumenthal AL, Daniels MS, Feit H, Gardner K, Hurst S, Kobelka C, Lee C, Nagy R, Rauen KA, Slopis JM, Suwannarat P, Westman JA, Zanko A, Korf BR, Messiaen LM. Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas. Nat Genet 46(2):182-7, 2014. e-Pub 2013. PMID: 24362817.
- Debnam JM, Mahfouz YM, Ketonen L, Slopis JM, McCutcheon IE, Guha-Thakurta N. Multidetector CT with 3-dimensional volume rendering in the evaluation of the spine in patients with Neurofibromatosis type 1: a retrospective review in 73 patients. Scoliosis 9:15, 2014. e-Pub 2014. PMID: 25852768.
- Piotrowski A, Xie J, Liu YF, Poplawski AB, Gomes AR, Madanecki P, Fu C, Crowley MR, Crossman DK, Armstrong L, Babovic-Vuksanovic D, Bergner A, Blakeley JO, Blumenthal AL, Daniels MS, Feit H, Gardner K, Hurst S, Kobelka C, Lee C, Nagy R, Rauen KA, Slopis JM, Suwannarat P, Westman JA, Zanko A, Korf BR, Messiaen LM. Germiline loss-of-function mutations in LZTR1 predispose to an inherited idsorder of multiple schwannomas. Nature Genetics 46:182-187, 2013.
- Angelo LS, Maxwell DS, Wu JY, Sun D, Hawke DH, McCutcheon IE, Slopis JM, Peng Z, Bornmann WG, Kurzrock R. Binding partners for curcumin in human schwannoma cells: biologic implications. Bioorg Med Chem 21(4):932-9, 2013. e-Pub 2012. PMID: 23294827.
- Sadighi Z, Slopis JM. Pilocytic Astrocytoma: a disease with evolving molecular heterogeneity. JCN, 2012.
- Zipp L, Schwartz KM, Hewer E, Yu Y, Stippich C, Slopis JM. Magnetic resonance imaging and computed tomography findings in pediatric giant cell glioblastoma. Clin Neuroradiol 22(4):359-63, 2012. PMID: 22286149.
- Koenig MK, Hebert AA, Roberson J, Samuels J, Slopis J, Woerner A, Northrup H. Topical rapamycin therapy to alleviate the cutaneous manifestations of tuberouos sclerosis complex: a double-blind, randomized, controlled trial to evaluate the safety and efficacy of topically applied rapamycin. Drugs RD 12(3):121-126, 2012.
- Subbiah V, Slopis J, Ketonen L, Hamilton J. Treatment of patients with advanced neurofibromatosis type 2 (NF2) with novel molecularly targeted therapies: from bench to bedside. J Clin Oncol 30(5):e64-e68, 2012. e-Pub 2011.
- Subbiah V, Slopis J, Hong DS, Ketonen LM, Hamilton J, McCutcheon IE, Kurzrock R. Treatment of patients with advanced neurofibromatosis type 2 with novel molecularly targeted therapies: from bench to bedside. J Clin Oncol 30(5):e64-8, 2012. e-Pub 2011. PMID: 22203760.
- Angelo LS, Wu JY, Meng F, Sun M, Kopetz S, McCutcheon IE, Slopis JM, Kurzrock R. Combining Curcumin (Diferuloylmethane) and Heat Shock Protein Inhibition for Neurofibromatosis 2 Treatment: Analysis of Response and Resistance Pathways. Mol Cancer Ther 10(11):2094-2103, 2011. e-Pub 2011. PMID: 21903608.
- Pearlman M, Frye R, Butler I, Papanicolaou AC, Castillo E, Slopis J. Patterns of electromagnetic activity recorded from neoplastic tissue. J Neurooncol 105(2):445-449, 2011. e-Pub 2011. PMID: 21573889.
- Lopez G, Torres K, Liu J, Hernandez B, Young E, Belousov R, Bolshakov S, Lazar AJ, Slopis JM, McCutcheon IE, McConkey D, Lev D. Autophagic survival in resistance to histone deacetylase inhibitors: novel strategies to treat malignant peripheral nerve sheath tumors. Cancer Res 71(1):185-96, 2011. e-Pub 2010. PMID: 21084276.
- Rokes C, Ketonen LM, Fuller GN, Weinberg J, Slopis JM, Wolff JE. Imaging and spectroscopic findings in meningioangiomatosis. Pediatr Blood Cancer 53(4):672-4, 2009. e-Pub 2009. PMID: 19544396.
- Zou C, Smith KD, Liu J, Lahat G, Myers S, Wang WL, Zhang W, McCutcheon IE, Slopis JM, Lazar AJ, Pollock RE, Lev D. Clinical, pathological, and molecular variables predictive of malignant peripheral nerve sheath tumor outcome. Ann Surg 249(6):1014-22, 2009. PMID: 19474676.
- Zou CY, Smith KD, Zhu QS, Liu J, McCutcheon IE, Slopis JM, Meric-Bernstam F, Peng Z, Bornmann WG, Mills GB, Lazar AJ, Pollock RE, Lev D. Dual targeting of AKT and mammalian target of rapamycin: A potential therapeutic approach for malignant peripheral nerve sheath tumor. Mol Cancer Ther 8(5):1157-68, 2009. e-Pub 2009. PMID: 19417153.
- Koenig MK, Sitton CW, Wang M, Slopis JM. Central nervous system complications of blastic hyperleukocytosis in childhood acute lymphoblastic leukemia: diagnostic and prognostic implications. J Child Neurol 23(11):1347-52, 2008. PMID: 18984849.
- Billingsley RL, Jackson EF, Slopis JM, Swank PR, Mahankali S, Moore BD. Functional MRI of visual-spatial processing in neurofibromatosis, type I. Neuropsychologia 42(3):395-404, 2004. PMID: 14670578.
- Billingsley RL, Jackson EF, Slopis JM, Swank PR, Mahankali S, Moore BD. Functional magnetic resonance imaging of phonologic processing in neurofibromatosis 1. J Child Neurol 18(11):731-40, 2003. PMID: 14696899.
- Schrimsher GW, Billingsley RL, Slopis JM, Moore BD. Visual-spatial performance deficits in children with neurofibromatosis type-1. Am J Med Genet A 120A(3):326-30, 2003. PMID: 12838550.
- Billingsley RL, Slopis JM, Swank PR, Jackson EF, Moore BD. Cortical morphology associated with language function in neurofibromatosis, type I. Brain Lang 85(1):125-39, 2003. PMID: 12681352.
- Chan KW, Mullen CA, Worth LL, Choroszy M, Koontz S, Tran H, Slopis J. Lorazepam for seizure prophylaxis during high-dose busulfan administration. Bone Marrow Transplant 29(12):963-5, 2002. PMID: 12098063.
- Billingsley RL, Schrimsher GW, Jackson EF, Slopis JM, Moore BD. Significance of planum temporale and planum parietale morphologic features in neurofibromatosis type 1. Arch Neurol 59(4):616-22, 2002. PMID: 11939897.
- Billingsley RL, Lang FF, Slopis JM, Schrimsher GW, Ater JL, Moore BD. Visual-spatial neglect in a child following sub-cortical tumor resection. Dev Med Child Neurol 44(3):191-9, 2002. PMID: 12008674.
- Neville HL, Seymour-Dempsey K, Slopis J, Gill BS, Moore BD, Lally KP, Andrassy RJ. The role of surgery in children with neurofibromatosis. J Pediatr Surg 36(1):25-29, 2001. PMID: 11150433.
- Vassilopoulou-Sellin R, Klein MJ, Slopis JK. Growth hormone deficiency in children with neurofibromatosis type 1 without suprasellar lesions. Pediatr Neurol 22(5):355-8, 2000. PMID: 10913726.
- Kayl AE, Moore BD, Slopis JM, Jackson EF, Leeds NE. Quantitative morphology of the callosum in children with neurofibromatosis and attention-deficit hyperactivity disorder. J Child Neurol 15(2):90-96, 2000. PMID: 10695893.
- Moore BD, Slopis JM, Jackson EF, De Winter AE, Leeds NE. Brain volume in children with neurofibromatosis: relation to neuropsychological status. Neurology 54(4):25-9, 2000. PMID: 10690986.
- Worth LL, Slopis JM, Herzog CE. Congenital hepatoblastoma and schizencephaly in an infant with Beckwith-Wiedemann syndrome. Med Pediatr Oncol 33(6):591-3, 1999. PMID: 10573588.
- De Winter AE, Moore BD, Slopis JM, Ater JL, Copeland DR. Brain tumors in children with neurofibromatosis: additional neuropsychological morbidity?. Neuro Oncol 1(4):275-81, 1999. PMID: 11550319.
- Kramer LA, Villar-Cordova C, Wheless JW, Slopis J, Yeakley J. Magnetic resonance angiography of primary varicella vasculitis: report of two cases. J Magn Reson Imaging 9(3):491-6, 1999. PMID: 10194723.
- Kramer LA, Crino JP, Slopis J, Hankins L, Yeakley J. Capillary Hemangioma of the Neck: Prenatal MR Findings. AJNR Am J Neuroradiol 18(8):1432-1434, 1997. PMID: 9296183.
- Ater JL, Moore BD, Francis DJ, Castillo R, Slopis J, Copeland DR. Correlation of medical and neurosurgical events with neuropsychological status in children at diagnosis of astrocytoma: utilization of a neurological severity score. J Child Neurol 11(6):462-9, 1996. PMID: 9120225.
- Moore BD, Slopis JM, Schomer D, Jackson EF, Levy BM. Neuropsychological significance of areas of high signal intensity on brain MRIs of children with neurofibromatosis. Neurology 46(6):1660-8, 1996. PMID: 8649566.
- Lin SN, Slopis JM, Butler IJ, Caprioli RM. In Vivo Microdialysis and Gas Chromatography/Mass Spectrometry for Studies in Release of N-Acetylaspartylglumate and N-Acetylaspartate in Rat Brain Hypothalamus. J Neurosci Methods 62(1-2):199-205, 1995. PMID: 8750104.
- Dimachkie MM, Austin SG, Slopis JM, Vriesendorp FJ. Critical Illness polyneuropathy in adolescence. J Child Neurol 9(5):193, 1995. PMID: 7499764.
- Moore BD, Ater JL, Needle MN, Slopis J, Copeland DR. Neurophysichological profiles of children with neurofibromatosis, brain tumor, or both. J Child Neurol 9(4):368-377, 1994. PMID: 7822726.
- Mancias P, Slopis JM, Yeakley JW, Vriesendorp FJ. Combined brachial plexopathy and root avulsion in a neonate. Muscle Nerve 17(10):1237-1238, 1994. PMID: 7935545.
- Ramirez M, Wilkins I, Kramer L, Slopis J, Taylor SR. Prenatal diagnosis of unilateral megalencephaly by real-time ultrasonography. Am J Obstet Gynecol 170(5):1384-1385, 1994. PMID: 8178875.
- Slopis JM, Jackson EF, Narayana PA, Papasozomenos SC, Butler IJ. Proton Magnetic resonance imaging and spectroscopic studies of the pathogenesis and treatment of juvenile. J Child Neurol 8(3):242-249, 1993. PMID: 8409266.
- Dominguez R, Aguirre Vila-Coro A, Slopis JM, Bohan TP. Brain and ocular abnormalities in infants with in utero exposure to cocaine and other street drugs. Am J Dis Child 145(6):688-95, 1991. PMID: 1709777.
- Narayana PA, Slopis JM, Jackson EF, Jankovic J, Butler IJ. Proton magnetic resonance spectroscopic studies of hypertrophied muscle: Effect of botulinum toxin treatment. Invest Radiol 26(1):58-64, 1991. PMID: 2022454.
- Fotedar LK, Slopis JM, Narayana PA, Fenstermacher MJ, Pivarnik J, Butler IJ. Proton magnetic resonance of exercise induced water changes in gastrocnemius muscle. J Appl Physiol 69(5):1695-1701, 1990. PMID: 2177054.
- Narayana PA, Slopis JM, Jackson EF, Hazle JD, Kulkarni MV, Butler IJ. In vivo muscle proton magnetic resonance spectroscopy studies in mitochondrial cytopathy. Magn Reson Imaging 7(2):133-139, 1989. PMID: 2716480.
- Takaue Y, Slopis JM, Anzai T, Robertson R, Jaffe N. Successful treatment of pulmonary and abdominal metastatic osteosarcoma. Med Pediatr Oncol 13(3):126-128, 1985. PMID: 3857430.
- Kendall DA, Duman R, Slopis J, Enna SJ. The influence of ACTH and Yohimbine on antidepressant-induced decline in rat brain neurotransmitter receptor binding and function. J Pharmacol Exp Ther 222(3):566-571, 1982. PMID: 6286924.
- Kitagawa RH, Slopis JM, Tummala S, Lin V, Smitherman S, McCutcheon IE. Surgical treatment of intrinsic tumors of the sciatic nerve. Neurosurgery.
- Wilson A, Slopis JM, Andrassy R, Dhingra S, Austin M. Surgical management of an appendiceal neurofibroma in a neurofibromatosis-1 patient: A case report. Journal of Pediatric Surgery Case Reports.
Abstracts
- Slopis JM, Arevalo O, Bell CS, Hebert AA, Northrup H, Riascos RF, Samuels JA, Smith KC, Tate P, Koenig MK.. Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis-1 with Everolimus: A Phase II, Open-Label, Single-Arm Trial. Drugs in R&D 18(4):295-302, 2018. PMID: 30284154.
- Kochat V1,2 , Raman A2, Landers SM1, Terranova C2, Wu CC2, Mao X2, Ingram D3, Mulder ZA1, Yeagley MA1, Bierd H2, Bhalla A1, McCutcheon I4, Slopis J5, Zhang J2,6, Futreal A2, Wang WL3, Lazar A3, Rai K2, and Torres KE1,2. CHROMATIN STATE TRANSITIONS ASSOCIATED WITH PRC2 FUNCTIONAL LOSS DRIVE A DE-DIFFERENTIATED PHENOTYPE IN MALIGNANT PERIPHERAL NERVE SHEATH TUMORS. Connective Tissue Oncology Society, 2018.
- Joy S, Miller M, Slopis JM. Case Study: A patient with Neurofibromatosis Type 1, Accessory renal artery and Pheochromotocytoma, 2014.
- Kivlin CM, Ma XY, Ingram D, Al Sannaa GA, May C, Garnett J, Bolshakov S, McCutcheon I, Slopis JM, Lev D, Lazar AJ, Torres KE. An Innovative Combination Therapy for the Treatment of Malignant Peripheral Nerve Sheath Tumor (MPNST), 2013.
- Kivlin, CM, Ma XY, Zhu QS, Belousov R, Ingram D, Al Sannaa GA, May C, Garnett J, Bolshakov S, McCutcheon I, Slopis JM, Pollock RE, Lev D, Lazar AJ, Torres KE. Downregulation of ERCC6 is a Potential Mechanism for the Effect of Parp Inhibition in Malignant Peripheral Nerve Sheath Tumor (MPNST). Presented at the CTOS 2013 Annual Meeting, October 30-November 2, 2013 New York, 2013.
- Kivlin CM, Ma XY, Ingram D, Al Sannaa GA, Feng Y, May C, Bolshakov S, McCutcheon I, Slopis JM, Lev D, Lazar AJ, Torres KE. BMN 673, A Novel Potent Parp Inhibitor for the Treatment of Malignant Peripheral Nerve Sheath Tumore (MPNST). Presented at the CTOS 2013 Annual Meeting, October 30-November 2, 2013, New York, 2013.
- Ma X, May C, Kivlin CM, Uzunparmak B, Han L, Zhou F, Ingram D, Al Sannaa GA, Garnett J, Bolshakov S, McCutcheon I, Slopis JM, Lev D, Lazar AJ, Torres KE. Inhibition of Axl Enhance the Sensitivity of Malignant Peripheral Nerve Sheath Tumores to Mek Inhibition, 2013.
- Young ED, Ingram D, Metcalf-Doetsch W, Khan D, LeLoarer F, Lazar A JF, McCutcheon IE, Slopis JM, Torres KE, Pollock RE, Lev D. A Clinicopathologic Portrait of Sporadic Peripheral Schwannomas, 2013.
- Al Sannaa G, Ingram D, Unlu O, Slopis J, McCutcheon I, Torres K, Lazar A. The Impact of Neurofibromatosis Type 1 Status on Malignant Peripheral Nerve Sheath Tumors Patient Outcom. Presented at the CTOS 2013 Annual Meeting, October 30-November 2, 2013, New York, 2013.
- Sadighi ZS, Pearlman ML, Slopis JM, Vats TS, Khatua S. Diffuse leptomeningeal relapse following gross total resection in a spinal cord pilocytic astrocytoma with oligodendroglial features and 1p19q deletion. Neuro-Oncology 13(Suppl 3):iii42, 2011.
- Sadighi Z, Vats T, Khatua S, Ater J, Slopis J, Dhamne C, Schiffman J. Looking through the patient's eyes. Proceedings of 43rd Congress of the International Society for Paediatric Oncology 2011 Auckland, New Zealand, 2011.
- Subbiah V, Slopis JM, Hong DS, Angelo LS, McCutcheon IE, Kurzrock R. Treatment of patients with advanced neurofibromatosis type 2 (NF2) with novel molecularly targeted therapies. J Clin Oncol 29(Suppl), 2011.
- Slopis JM. Spinal Malformations in Neurofibromatosis Type I. Presented at the Tumor Foundation Neurofibromatosis Research Meeting in Aspen, CO, 2006. e-Pub 2006.
- Slopis JM. Early Childhood Development in Neurofibromatosis Type I. Presented in Platform Session at Children's Tumor Foundation Neurofibromatosis Research Meeting in Aspen, CO, 2006.
- De Winter, A, Moore BD, Slopis JM, Jackson EF. Relationship of corpus callosum morphology to symptoms of attention deficit hyperactivity disorder in children diagnosed with neurofibromatosis, type 1. Journal of the International Neuropsychological Society 5:2, 1999.
- Slopis JM. Neuroanatomical predictors of neurospsychological functioning in children with neurofibromatosis. J. Clin Exp Neuropsychol 4:223, 1998.
- Narayana PA, Slopis JM, Jackson EF, Fotedar LK, Butler IJ. In vivo muscle magnetic resonance spectroscopy in a family with mitochondrial cytopathy: A defect in fat metabolism. 7th Annual Meeting of the Society of Magnetic Resonance in Medicine Book of Abstracts:300, 1988.
- Duman R, Slopis JM, Kendall DA, Enna SJ. Facilitation of the neurochemical response to antidepressants by ACTH and Yohimbine. Proceedings of the Society of Neuroscience 7:104, 1981.
- Debnam JM, Ketonen L, Slopis JM, McCutcheon IE, Hamberg LM, Hunter GJ. Multidetector CT Evaluation of the Spine in Patients with Neurofibromatosis Type I. Presented at the American Society of Neuroradiology 45th Annual Meeting.
Grant & Contract Support
Date: | 2011 - 2014 |
Title: | Topical Rapamycin Therapy to Relieve Cutaneous Manifestations of Tuberous Sclerosis Complex |
Funding Source: | DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP) |
Role: | Co-Investigator |
ID: | TS100017 |
Title: | Oral Afinitor to Treat Cutaneous Neurofibromata in NF 1-Investigator Initiated Trial; Approved through IRB, enrolling subjects-January 2015 |
Funding Source: | Novartis |
Role: | Principal Investigator |
Patient Reviews
Comments (37)
Great job.
Dr. Slopis is bery intelligent. He explains evertto me and answers all my questions. His bedside manner is the best I have experienced. I am so blessed and happy he is one of my doctors.
I have been looking for answers to the physical medical challenges that I was facing for three years and the first oncologist that I spoke with in a different department dismissed the symptoms that I was experiencing, but I knew something wasn't right. I am so appreciative...
Dr. Slopis is wonderful. We've been seeing, my son's been seeing him for 12 years now. Every year that we come, he remembers about [Name]. He's thorough. He's so knowledgeable. He makes us feel so much better. He's got a great bedside manner. He's a wonderful doctor. All of...
Dr Slopis listens well
Dr. Slopis is an amazing doctor; he is knowledgeable and kind.
Our provider was excellent, patient, knowledgable, addressed our concerns and eased our worries.
Dr. Slopis and his Team are truly professional, caring and on time.
Good
Dr. Slopis explains the diagnosis very well and gives great options for his patient
Thank you very much to Dr. Slopis and Kim. We appreciate all you do for [Name], and we look forward to working with you in the near future. Have a happy holidays guys. Blessings.
Excellent experience with Dr. Slopis. He answered every question I asked, provided information in a very complete and clear manner and made me feel very comfortable.
I too am a physician so I know good, bad and indifferent physicians. Dr. Slopis is a great physician and I feel fortunate to have him as my neurologist. MD Anderson is fortunate to have him on its staff
My daughter has been under the care of the NF clinic at Texas Children's for over 10 years, period. If I took every visit I had with that care, it would be half the care that Dr. Slopis provided to us in just our last two visits. He listened, he talked to my daughter like...
Dr. SLOPIS IS BY FAR THE BEST DOCTOR I HAVE EVER HAD AND STILL DO. HE IS VERY PASSIONATE ABOUT CARING FOR PATIENTS WITH NF EXTREMELY. RESECTFUL. DOES NOT DOWNGRADE YOUKNOWLEDGEABLE AND TAKES HIS TIME TO TALK WITH YOU.
I loved meeting Dr. Slopis. I have heard about him before--he's like a celebrity in the NF world. I felt so seen especially since he knew so much about my condition.
The provider was very knowledgeable about my child's case. She allowed us time to ask questions and answered all of our questions and was very encouraging.
Yes, he is one of the best providers that I've had ever since I was a child, and I highly recommend him. Thank you so much. Bye.
Dr. John Slopis is the very best. Patient, kind, thorough. There is no one else like him. I have been a patient at MDA for almost 35 years and have known him almost this long. MDA needs more providers like him.
Dr. Slopis has always been so amazing with [Name]. He is smart and knowledgeable and compassionate and kind. We wouldn't be where we are without him.
Dr.Slopis is a understanding doctor he listen he take his time never in a rush love Dr.Slopis. He cares about his patience.
This provider took plenty of time and thoroughly visited and explained everything to us. They did above and beyond an excellent job.
Love Dr. Slopis. He takes his time. He listens to what you have to say.
Slopis is incredible. We've had outstanding care the past several years with him and his team.
And I am very satisfied with all the doctors and the help they are giving my son, thank God and thank you to all the doctors.
Dr slopis is great. I like how he takes his time with me.I wish my most recent mri images would have been loaded in the system for me to see at my visit. I also would like to see notes about my most recent visit in my chart about things we discussed. And accessing my...
I left this appointment and told my peers that this was, by far, the best experience I have ever had at a doctor's appointment. This statement was made with the understanding that I manage the complex care of several adults and children.
From the initial request for an appointment to the scheduler calling and setting up the appointment was above my expectations. Once the appointment was setup, had several calls with the appointment team on what to expect, instructions to upload medical records etc. On the...
Dr. Slopis is true credit to his profession. I feel totally confident in his treatments to keep me to the best I can be.
Dr. Slopis is the best
Dr. Slopis and his nurse, Rachel Bingham, have been amazing with my daughter and with us, her family. They are so, so willing to answer any questions, always available to discuss and explain. And we are so grateful to have him as part of my daughter's medical team.
My son has been under the care of Dr Slopis since he was 2 yrs old. He will be 21 in November. We see him several times a year for MRI's and follow up to keep an eye on his brain tumor. We love Dr. Slopis. He is the best thing that ever happened to my son.
Professional and caring
Dr Slopis is the best. I can't imagine battling NF without him.
I believe they are the best doctors.
Dr. Slopis always provides a safety zone for my son and provide him the comfortability of speaking openly about any issue. Dr. Swinford provides a comfort and safety area for my son to feel free about speaking to her about any issue as well.
Dr. Slopis is always courteous; patient with me, and always answers my concern and questions.
CV information above last modified July 13, 2022