Dr. Kim-Anh Do
Department of Biostatistics, Division of Division of Discovery Science
About Dr. Do
Kim-Anh Do, Ph.D., is Professor and former Chair in the Department of Biostatistics at MD Anderson, a recipient of the Faculty Scholar Award at MD Anderson in 2003, the Texas 4000 Distinguished Professorship in 2013, and the Electa C. Taylor Chair for Cancer Research in 2017. She is a Fellow of the American Statistical Association, the American Association for the Advancement of Science (AAAS) and the Royal Statistical Society and is an Elected Member of the International Statistical Institute. She has served as a primary statistician or co-investigator on several National Institutes of Health (NIH) funded grants and clinical trials in prostate cancer, epidemiology, leukemia, upper aerodigestive cancer, breast cancer and brain cancer, including the Early Detection Research Network (EDRN) grant, the Prostate SPORE (as Director of the Biostatistics Core), the Breast SPORE, and the Brain SPORE at M. D. Anderson. She has significant publications in statistical methodology, computing, biomedical, and in other applied specialist journals. Her most recent interest is in the development of clustering and analytic methods for genomic and proteomic expressions, as well as microbiome data and recently spatial transcriptomic data. She has developed bioinformatics software and authored books: (i) Analyzing microarray gene expression data; (ii) Bayesian Inference for Gene Expression and Proteomics; and (iii) Advances in Statistical Bioinformatics--Models and Integrative Inference for High-Throughput Data. Her extensive contribution to statistical, medical and cancer research has resulted in more than 260 published articles to date. Additional information regarding Dr. Do's educational and professional activities can be found here https://kimanhdomda.github.io/COSMIC/
Present Title & Affiliation
Primary Appointment
Professor and Former Department Chair (7/2012-8/2020)), Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Adjunct Professor, Department of Statistics, Rice University, Houston, TX
Adjunct Professor, Department of Statistics, Texas A&M University, College Station, TX
Research Interests
Computational Statistics and Biostatistics Bioinformatics Statistical Genetics Non-parametric Statistical Methods
Education & Training
Degree-Granting Education
| 1990 | Stanford University, Stanford, CA, USA, PHD, Statistics |
| 1985 | Stanford University, Stanford, CA, USA, MS, Statistics |
| 1983 | University of Queensland, Brisbane, AUS, B.Sc, Mathematics and Computer Science |
Honors & Awards
| 2017 | Electa C. Taylor Chair for Cancer Research, The University of Texas MD Anderson Cancer Center |
| 2015 | Elected to the Electorate Nominating Committee for Statistics, AAAS |
| 2013 | Texas 4000 Distinguished Professorship, The University Texas M D Anderson Cancer Center |
| 2013 | Elected Fellow, American Association for the Advancement of Science |
| 2012 | Elected Member, International Statistical Institute |
| 2006 | Fellow, American Statistical Association |
| 2005 | Fellow, Royal Statistical Society |
| 2003 | Faculty Scholar Award, University of Texas M.D. Anderson Cancer Center |
| 1994 | Australian Academy of Science Travel Award |
| 1983 | Amy R. Hughes Award, Australian Federation of University Women, Australia |
| 1982 | Caltex Woman Graduate of the Year, Postgraduate Scholarship, University of Queensland |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Irajizad E, Han CY, Celestino J, Wu R, Murage E, Spencer R, Dennison JB, Vykoukal J, Long JP, Do KA, Drescher C, Lu K, Lu Z, Bast RC, Hanash S, Fahrmann JF. A Blood-Based Metabolite Panel for Distinguishing Ovarian Cancer from Benign Pelvic Masses. Clin Cancer Res 28(21):4669-4676, 2022. PMID: 36037307.
- Su X, Li Y, Müller P, Hsu CW, Pan H, Do KA. A semi-mechanistic dose-finding design in oncology using pharmacokinetic/pharmacodynamic modeling. Pharm Stat 21(6):1149-1166, 2022. e-Pub 2022. PMID: 35748220.
- Darbaniyan F, Zheng H, Kanagal-Shamanna R, Lockyer P, Montalban-Bravo G, Estecio M, Lu Y, Soltysiak KA, Chien KS, Yang H, Sasaki K, Class C, Ganan-Gomez I, Do KA, Garcia-Manero G, Wei Y. Transcriptomic Signatures of Hypomethylating Agent Failure in Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia. Exp Hematol 115:44-53, 2022. e-Pub 2022. PMID: 36150563.
- Schwabkey ZI, Wiesnoski DH, Chang CC, Tsai WB, Pham D, Ahmed SS, Hayase T, Ortega Turrubiates MR, El-Himri RK, Sanchez CA, Hayase E, Frenk Oquendo AC, Miyama T, Halsey TM, Heckel BE, Brown AN, Jin Y, Raybaud M, Prasad R, Flores I, McDaniel L, Chapa V, Lorenzi PL, Warmoes MO, Tan L, Swennes AG, Fowler S, Conner M, McHugh K, Graf T, Jensen VB, Peterson CB, Do KA, Zhang L, Shi Y, Wang Y, Galloway-Pena JR, Okhuysen PC, Daniel-MacDougall CR, Shono Y, Burgos da Silva M, Peled JU, van den Brink MRM, Ajami N, Wargo JA, Reddy P, Valdivia RH, Davey L, Rondon G, Srour SA, Mehta RS, Alousi AM, Shpall EJ, Champlin RE, Shelburne SA, Molldrem JJ, Jamal MA, Karmouch JL, Jenq RR. Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment. Sci Transl Med 14(671):eabo3445, 2022. e-Pub 2022. PMID: 36383683.
- Das P, Peterson CB, Ni Y, Reuben A, Zhang J, Zhang J, Do KA, Baladandayuthapani V. Bayesian hierarchical quantile regression with application to characterizing the immune architecture of lung cancer. Biometrics. e-Pub 2022. PMID: 36239535.
- Li Z, Wang Y, Ganan-Gomez I, Colla S, Do KA. A machine learning-based method for automatically identifying novel cells in annotating single-cell RNA-seq data. Bioinformatics 38(21):4885-4892, 2022. PMID: 36083008.
- Wei Y, Zheng H, Lockyer PP, Darbaniyan F, Li Z, Kanagal-Shamanna R, Soltysiak KA, Yang H, Ganan-Gomez I, Montalban-Bravo G, Chien KS, Do KA, Daver N, Garcia-Manero G. MDM2 antagonist improves therapeutic activity of azacitidine in myelodysplastic syndromes and chronic myelomonocytic leukemia. Leuk Lymphoma:1-11. e-Pub 2022. PMID: 36059252.
- Wei Y, Kanagal-Shamanna R, Zheng H, Bao N, Lockyer PP, Class CA, Darbaniyan F, Lu Y, Lin K, Yang H, Montalban-Bravo G, Ganan-Gomez I, Soltysiak KA, Do KA, Colla S, Garcia-Manero G. Cooperation between KDM6B overexpression and TET2 deficiency in the pathogenesis of chronic myelomonocytic leukemia. Leukemia 36(8):2097-2107, 2022. e-Pub 2022. PMID: 35697791.
- Irajizad E, Fahrmann JF, Long JP, Vykoukal J, Kobayashi M, Capello M, Yu CY, Cai Y, Hsiao FC, Patel N, Park S, Peng Q, Dennison JB, Kato T, Tai MC, Taguchi A, Kadara H, Wistuba II, Katayama H, Do KA, Hanash SM, Ostrin EJ. A Comprehensive Search of Non-Canonical Proteins in Non-Small Cell Lung Cancer and Their Impact on the Immune Response. Int J Mol Sci 23(16), 2022. e-Pub 2022. PMID: 36012199.
- Fahrmann JF, Marsh T, Irajizad E, Patel N, Murage E, Vykoukal J, Dennison JB, Do KA, Ostrin E, Spitz MR, Lam S, Shete S, Meza R, Tammemägi MC, Feng Z, Hanash SM. Blood-Based Biomarker Panel for Personalized Lung Cancer Risk Assessment. J Clin Oncol 40(8):876-883, 2022. e-Pub 2022. PMID: 34995129.
- Shi Y, Zhang L, Peterson CB, Do KA, Jenq RR. Performance determinants of unsupervised clustering methods for microbiome data. Microbiome 10(1):25, 2022. e-Pub 2022. PMID: 35120564.
- Shih DJH, Ruoxing L, Müller P, Zheng WJ, Do KA, Lin SY, Carter SL. CNGPLD: Case-control copy-number analysis using Gaussian process latent difference. Bioinformatics. e-Pub 2022. PMID: 35176131.
- Shih DJH, Chen MK, Yin J, McGrail DJ, Dai H, Wei R, Zhang J, Zheng WJ, Do KA, Yang L, Hung MC, Lin SY. Exploiting induced vulnerability to overcome PARPi resistance and clonal heterogeneity in BRCA mutant triple-negative inflammatory breast cancer. Am J Cancer Res 12(1):337-354, 2022. e-Pub 2022. PMID: 35141022.
- Irajizad E, Wu R, Vykoukal J, Murage E, Spencer R, Dennison JB, Moulder S, Ravenberg E, Lim B, Litton J, Tripathym D, Valero V, Damodaran S, Rauch GM, Adrada B, Candelaria R, White JB, Brewster A, Arun B, Long JP, Do KA, Hanash S, Fahrmann JF. Application of Artificial Intelligence to Plasma Metabolomics Profiles to Predict Response to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer. Front Artif Intell 5:876100, 2022. e-Pub 2022. PMID: 36034598.
- Kanagal-Shamanna R, Orazi A, Hasserjian RP, Arber DA, Reichard K, Hsi ED, Bagg A, Rogers HJ, Geyer J, Darbaniyan F, Do KA, Devins KM, Pozdnyakova O, George TI, Cin PD, Greipp PT, Routbort MJ, Patel K, Garcia-Manero G, Verstovsek S, Medeiros LJ, Wang SA, Bueso-Ramos C. Correction to: Myelodysplastic/myeloproliferative neoplasms-unclassifiable with isolated isochromosome 17q represents a distinct clinico-biologic subset: a multi-institutional collaborative study from the Bone Marrow Pathology Group. Mod Pathol. e-Pub 2021. PMID: 34903824.
- Chen Y, Capello M, Rios Perez MV, Vykoukal JV, Roife D, Kang Y, Prakash LR, Katayama H, Irajizad E, Fleury A, Ferri-Borgogno S, Baluya DL, Dennison JB, Do KA, Fiehn O, Maitra A, Wang H, Chiao PJ, Katz MHG, Fleming JB, Hanash SM, Fahrmann JF. CES2 sustains HNF4α expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop. Mol Metab:101426. e-Pub 2021. PMID: 34971802.
- Fahrmann JF, Wasylishen AR, Pieterman CRC, Irajizad E, Vykoukal J, Murage E, Wu R, Dennison JB, Krishna H, Peterson CB, Lozano G, Zhao H, Do KA, Halperin DM, Agarwal SK, Blau JE, Del Rivero J, Nilubol N, Walter MF, Welch JM, Weinstein LS, Vriens MR, van Leeuwaarde RS, van Treijen MJC, Valk GD, Perrier ND, Hanash SM. A blood-based polyamine signature associated with MEN1 duodenopancreatic neuroendocrine tumor progression. J Clin Endocrinol Metab 106(12):e4969-e4980, 2021. e-Pub 2021. PMID: 34318891.
- Kanagal-Shamanna R, Orazi A, Hasserjian RP, Arber DA, Reichard K, Hsi ED, Bagg A, Rogers HJ, Geyer J, Darbaniyan F, Do KA, Devins KM, Pozdnyakova O, George TI, Cin PD, Greipp PT, Routbort MJ, Patel K, Garcia-Manero G, Verstovsek S, Medeiros LJ, Wang SA, Bueso-Ramos C. Myelodysplastic/myeloproliferative neoplasms-unclassifiable with isolated isochromosome 17q represents a distinct clinico-biologic subset: a multi-institutional collaborative study from the Bone Marrow Pathology Group. Mod Pathol. e-Pub 2021. PMID: 34775472.
- Zhang L, Shi Y, Jenq RR, Do KA, Peterson CB. Bayesian compositional regression with structured priors for microbiome feature selection. Biometrics 77(3):824-838, 2021. e-Pub 2020. PMID: 32686846.
- Tanaka I, Dayde D, Tai MC, Mori H, Solis LM, Tripathi SC, Fahrmann JF, Unver N, Parhy G, Jain R, Parra ER, Murakami Y, Aguilar-Bonavides C, Mino B, Celiktas M, Dhillon D, Casabar JP, Nakatochi M, Stingo F, Baladandayuthapani V, Wang H, Katayama H, Dennison JB, Lorenzi PL, Do KA, Fujimoto J, Behrens C, Ostrin EJ, Rodriguez-Canales J, Hase T, Fukui T, Kajino T, Kato S, Yatabe Y, Hosoda W, Kawaguchi K, Yokoi K, Chen-Yoshikawa TF, Hasegawa Y, Gazdar AF, Wistuba II, Hanash S, Taguchi A. SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1-Negative Lung Adenocarcinomas. J Natl Cancer Inst. e-Pub 2021. PMID: 34524427.
- Karakas C, Francis AM, Ha MJ, Wingate HF, Meena RA, Yi M, Rasaputra KS, Barrera AMG, Arun B, Do KA, Sahin A, Keyomarsi K, Hunt KK. Cytoplasmic Cyclin E Expression Predicts for Response to Neoadjuvant Chemotherapy in Breast Cancer. Ann Surg 274(2):e150-e159, 2021. PMID: 31436549.
- Montalban-Bravo G, Kanagal-Shamanna R, Darbaniyan F, Siddiqui MT, Sasaki K, Wei Y, Yang H, Chien KS, Naqvi K, Jabbour E, Kadia TM, Daver N, DiNardo C, Ravandi F, Pemmaraju N, Bose P, Verstovsek S, Pierce S, Bueso-Ramos C, Patel K, Do KA, Kantarjian H, Garcia-Manero G. Clinical, genomic, and transcriptomic differences between myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) and myelodysplastic syndrome with ring sideroblasts (MDS-RS). Am J Hematol 96(7):E246-E249, 2021. e-Pub 2021. PMID: 33811786.
- Dayde D, Gunther J, Hirayama Y, Weksberg DC, Boutin A, Parhy G, Aguilar-Bonavides C, Wang H, Katayama H, Abe Y, Do KA, Hara K, Kinoshita T, Komori K, Shimizu Y, Tajika M, Niwa Y, Wang YA, DePinho R, Hanash S, Krishnan S, Taguchi A. Identification of Blood-Based Biomarkers for the Prediction of the Response to Neoadjuvant Chemoradiation in Rectal Cancer. Cancers (Basel) 13(14), 2021. e-Pub 2021. PMID: 34298853.
- Giuliani V, Miller MA, Liu CY, Hartono SR, Class CA, Bristow CA, Suzuki E, Sanz LA, Gao G, Gay JP, Feng N, Rose JL, Tomihara H, Daniele JR, Peoples MD, Bardenhagen JP, Geck Do MK, Chang QE, Vangamudi B, Vellano C, Ying H, Deem AK, Do KA, Genovese G, Marszalek JR, Kovacs JJ, Kim M, Fleming JB, Guccione E, Viale A, Maitra A, Emilia Di Francesco M, Yap TA, Jones P, Draetta G, Carugo A, Chedin F, Heffernan TP. PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma. Nat Commun 12(1):4626, 2021. e-Pub 2021. PMID: 34330913.
- Shu H, Chiang T, Wei P, Do KA, Lesslie MD, Cohen EO, Srinivasan A, Moseley TW, Chang Sen LQ, Leung JWT, Dennison JB, Hanash SM, Weaver OO. A Deep Learning Approach to Re-create Raw Full-Field Digital Mammograms for Breast Density and Texture Analysis. Radiol Artif Intell 3(4):e200097, 2021. e-Pub 2021. PMID: 34350403.
- Santos DA, Zhang L, Do KA, Bednarski BK, Robinson Ledet C, Limmer A, Gibson H, You YN. Chemotherapy and Abdominal Wall Closure Technique Increase the Probability of Postoperative Ventral Incisional Hernia in Patients With Colon Cancer. Am Surg:31348211011149. e-Pub 2021. PMID: 33877925.
- Fahrmann JF, Schmidt CM, Mao X, Irajizad E, Loftus M, Zhang J, Patel N, Vykoukal J, Dennison JB, Long JP, Do KA, Zhang J, Chabot JA, Kluger MD, Kastrinos F, Brais L, Babic A, Jajoo K, Lee LS, Clancy TE, Ng K, Bullock A, Genkinger J, Yip-Schneider MT, Maitra A, Wolpin BM, Hanash S. Lead-time trajectory of CA19-9 as an anchor marker for pancreatic cancer early detection. Gastroenterology 160(4):1373-1383.e6, 2021. e-Pub 2020. PMID: 33333055.
- Kanagal-Shamanna R, Montalban-Bravo G, Katsonis P, Sasaki K, Class CA, Jabbour E, Sallman D, Hunter AM, Benton C, Chien KS, Luthra R, Bueso-Ramos CE, Kadia T, Andreeff M, Komrokji RS, Al Ali NH, Short N, Daver N, Routbort MJ, Khoury JD, Patel K, Ganan-Gomez I, Wei Y, Borthakur G, Ravandi F, Do KA, Soltysiak KA, Lichtarge O, Medeiros LJ, Kantarjian H, Garcia-Manero G. Evolutionary action score identifies a subset of TP53 mutated myelodysplastic syndrome with favorable prognosis. Blood Cancer J 11(3):52, 2021. e-Pub 2021. PMID: 33677472.
- Zhang L, Shi Y, Do KA, Peterson CB, Jenq RR. ProgPerm: Progressive permutation for a dynamic representation of the robustness of microbiome discoveries. BMC Bioinformatics 22(1):126, 2021. e-Pub 2021. PMID: 33731016.
- Montalban-Bravo G, Darbaniyan F, Kanagal-Shamanna R, Ganan-Gomez I, Class CA, Sasaki K, Naqvi K, Wei Y, Yang H, Soltysiak KA, Chien KS, Bueso-Ramos C, Do KA, Kantarjian H, Garcia-Manero G. Type I Interferon Upregulation and Deregulation of Genes Involved in Monopoiesis in Chronic Myelomonocytic Leukemia. Leuk Res 101:106511, 2021. e-Pub 2021. PMID: 33517186.
- Fahrmann JF, Irajizad E, Kobayashi M, Vykoukal J, Dennison JB, Murage E, Wu R, Long JP, Do KA, Celestino J, Lu KH, Lu Z, Bast RC, Hanash S. A MYC-Driven Plasma Polyamine Signature for Early Detection of Ovarian Cancer. Cancers (Basel) 13(4), 2021. e-Pub 2021. PMID: 33671595.
- Abi Jaoude J, Kouzy R, Minsky BD, Fuller CD, Yuan Y, Do KA, Taniguchi CM, Ludmir EB. Sponsor-involved statistical analyses in Phase III cancer clinical trials. Int J Cancer 147(12):3579-3581, 2020. PMID: 32621758.
- Reyes-Gibby CC, Wang J, Zhang L, Peterson CB, Do KA, Jenq RR, Shelburne S, Shah DP, Chambers MS, Hanna EY, Yeung SJ, Shete S. Oral microbiome and onset of oral mucositis in patients with squamous cell carcinoma of the head and neck. Cancer 126(23):5124-5136, 2020. PMID: 32888342.
- Ha MJ, Kim J, Galloway-Peña J, Do KA, Peterson CB. Compositional zero-inflated network estimation for microbiome data. BMC Bioinformatics 21(Suppl 21):581, 2020. PMID: 33371887.
- Shi Y, Zhang L, Do KA, Peterson CB, Jenq RR. aPCoA: covariate adjusted principal coordinates analysis. Bioinformatics 36(13):4099-4101, 2020. PMID: 32339223.
- Galloway-Peña JR, Shi Y, Peterson CB, Sahasrabhojane P, Gopalakrishnan V, Brumlow CE, Daver NG, Alfayez M, Boddu PC, Khan MAW, Wargo JA, Do KA, Jenq RR, Kontoyiannis DP, Shelburne SA. Gut Microbiome Signatures are Predictive of Infectious Risk Following Induction Therapy for Acute Myeloid Leukemia. Clin Infect Dis 71(1):63-71, 2020. PMID: 31436833.
- Chien KS, Class CA, Montalban-Bravo G, Wei Y, Sasaki K, Naqvi K, Ganan-Gomez I, Yang H, Soltysiak KA, Kanagal-Shamanna R, Do KA, Kantarjian HM, Garcia-Manero G. LILRB4 Expression in Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome Based on Response to Hypomethylating Agents. Leuk Lymphoma 61(6):1493-1499, 2020. PMID: 32036728.
- Fahrmann JF, Vykoukal J, Fleury A, Tripathi S, Dennison JB, Murage E, Wang P, Yu CY, Capello M, Creighton CJ, Do KA, Long JP, Irajizad E, Peterson C, Katayama H, Disis ML, Arun B, Hanash S. Association between plasma diacetylspermine and tumor spermine synthase with outcome in triple negative breast cancer. J Natl Cancer Inst 112(6):607-616, 2020. PMID: 31503278.
- Montalban-Bravo G, Kanagal-Shamanna R, Class CA, Sasaki K, Ravandi F, Cortes JE, Daver N, Takahashi K, Short NJ, DiNardo CD, Jabbour E, Borthakur G, Naqvi K, Issa GC, Konopleva M, Khoury JD, Routbort M, Pierce S, Do KA, Bueso-Ramos C, Patel K, Kantarjian H, Garcia-Manero G, Kadia TM. Outcomes of acute myeloid leukemia with myelodysplasia related changes depend on diagnostic criteria and therapy. Am J Hematol 95(6):612-622, 2020. PMID: 32112433.
- Chekouo T, Stingo FC, Class CA, Yan Y, Bohannan Z, Wei Y, Garcia-Manero G, Hanash S, Do KA. Investigating protein patterns in human leukemia cell line experiments: A Bayesian approach for extremely small sample sizes. Stat Methods Med Res 29(4):1181-1196, 2020. PMID: 31172886.
- Montalban-Bravo G, Class CA, Ganan-Gomez I, Kanagal-Shamanna R, Sasaki K, Richard-Carpentier G, Naqvi K, Wei Y, Yang H, Soltysiak KA, Chien K, Bueso-Ramos C, Do KA, Kantarjian H, Garcia-Manero G. Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes. Leukemia 34(3):872-881, 2020. PMID: 31719677.
- Das P, Peterson CB, Do KA, Akbani R, Baladandayuthapani V. NExUS: Bayesian simultaneous network estimation across unequal sample sizes. Bioinformatics 36(3):798-804, 2020. PMID: 31504175.
- Kobayashi M, Katayama H, Irajizad E, Vykoukal JV, Fahrmann JF, Kundnani DL, Yu CY, Cai Y, Hsiao FC, Yang WL, Lu Z, Celestino J, Long JP, Do KA, Lu KH, Ladd JJ, Urban N, Bast RC, Hanash SM. Proteome Profiling Uncovers an Autoimmune Response Signature That Reflects Ovarian Cancer Pathogenesis. Cancers (Basel) 12(2), 2020. PMID: 32092936.
- Fahrmann JF, Rios Perez MV, Vykoukal JV, Irajizad E, Tripathi SC, Roife D, Bantis LE, Kang Y, Kundnani DL, Xu H, Prakash LR, Long JP, Katayama H, Fleury A, Ferri-Borgogno S, Baluya DL, Dennison JB, Aguilar-Bonavides C, Casabar JP, Celiktas M, Do K-A, Fiehn O, Maitra A, Wang H, Feng Z, Chiao PJ, Matthew, Fleming JB, Hanash SM. CES2 Expression in Pancreatic Adenocarcinoma Is Predictive of Response to Irinotecan and Is Associated With Type 2 Diabetes. JCO Precision Oncology 2020 4:426-436, 2020.
- Riquelme E, Zhang Y, Zhang L, Montiel M, Zoltan M, Dong W, Quesada P, Sahin I, Chandra V, San Lucas A, Scheet P, Xu H, Hanash SM, Feng L, Burks JK, Do KA, Peterson CB, Nejman D, Tzeng CD, Kim MP, Sears CL, Ajami N, Petrosino J, Wood LD, Maitra A, Straussman R, Katz M, White JR, Jenq R, Wargo J, McAllister F. Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes. Cell 178(4):795-806, 2019.
- Xing Y, Lin NU, Maurer MA, Chen H, Mahvash A, Sahin A, Akcakanat A, Li Y, Abramson V, Litton J, Chavez-MacGregor M, Valero V, Piha-Paul SA, Hong D, Do KA, Tarco E, Riall D, Eterovic AK, Wulf GM, Cantley LC, Mills GB, Doyle LA, Winer E, Hortobagyi GN, Gonzalez-Angulo AM, Meric-Bernstam F. Phase II trial of AKT inhibitor MK-2206 in patients with advanced breast cancer who have tumors with PIK3CA or AKT mutations, and/or PTEN loss/PTEN mutation. Breast Cancer Res 21(1):78, 2019. PMID: 31277699.
- Yan Y, Sun N, Wang H, Kobayashi M, Ladd JJ, Long JP, Lo KC, Patel J, Sullivan E, Albert T, Goodman GE, Do KA, Hanash SM. Whole genome-derived tiled peptide arrays detect pre-diagnostic autoantibody signatures in non-small cell lung cancer. Cancer Res 79(7):1549-1557, 2019. PMID: 30723114.
- Thomas PS, Class CA, Gandhi TR, Bambhroliya A, Do KA, Brewster AM. Demographic, clinical, and geographical factors associated with lack of receipt of physician recommended chemotherapy in women with breast cancer in Texas. Cancer Causes Control 30(4):409-415, 2019.
- Wang Y, Hu J, Do KA, Hobbs BP. An Efficient Nonparametric Estimate for Spatially Correlated Functional Data. Statistics in Biosciences 11(1):162-183, 2019.
- Kim J, Do KA, Ha MJ, Peterson CB. Bayesian inference of hub nodes across multiple networks. Biometrics 75(1):172-182, 2019. e-Pub 2018. PMID: 30051914.
- Gaudreau PO, Clairefond S, Class CA, Boulay PL, Chrobak P, Allard B, Azzi F, Pommey S, Do KA, Saad F, Trudel D, Young M, Stagg J. WISP1 is associated to advanced disease, EMT and an inflamed tumor microenvironment in multiple solid tumors. Oncoimmunology 8(5):e1581545, 2019. PMID: 31069142.
- Liu S, Li S, Wang B, Liu W, Gagea M, Chen H, Sohn J, Parinyanitikul N, Primeau T, Do KA, Vande Woude GF, Mendelsohn J, Ueno NT, Mills GB, Tripathy D, Gonzalez-Angulo AM. Cooperative effect of oncogenic MET and PIK3CA in an HGF-dominant environment in breast cancer. Mol Cancer Ther 18(2):399-412, 2019.
- Ha MJ, Banerjee S, Akbani R, Liang L, Mills GB, Do KA, Baladandayuthapani V. Personalized Integrated Network Modeling of the Cancer Proteome Atlas. Sci Rep 8(1):14924, 2018. PMID: 30297783.
- Class CA, Ha MJ, Baladandayuthapani V, Do KA. iDINGO - Integrative Differential Network Analysis in Genomics with Shiny Application. Bioinformatics 34(7):1243-1245, 2018. e-Pub 2017. PMID: 29194470.
- Tayob N, Stingo F, Do KA, Lok ASF, Feng Z. A Bayesian Screening Approach for Hepatocellular Carcinoma using Multiple Longitudinal Biomarkers. Biometrics 74(1):249-259, 2018. e-Pub 2017. PMID: 28482112.
- Chekouo T, Stingo FC, Doecke JD, Do KA. A Bayesian integrative approach for multi-platform genomic data: A kidney cancer case study. Biometrics 73(2):615-624, 2017. e-Pub 2016. PMID: 27669160.
- Hunt KK, Karakas C, Ha MJ, Biernacka A, Yi M, Sahin AA, Adjapong O, Hortobagyi GN, Bondy M, Thompson P, Cheung KL, Ellis IO, Bacus S, Symmans WF, Do KA, Keyomarsi K. Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer. Clin Cancer Res 23(12):2991-3002, 2017. e-Pub 2016. PMID: 27881578.
- Jonasch E, Hasanov E, Corn PG, Moss T, Shaw KR, Stovall S, Marcott V, Gan B, Bird S, Wang X, Do KA, Altamirano PF, Zurita AJ, Doyle LA, Lara PN, Tannir NM. A randomized phase 2 study of MK-2206 versus everolimus in refractory renal cell carcinoma. Ann Oncol 28(4):804-808, 2017. PMID: 28049139.
- Çeliktas M, Tanaka I, Tripathi SC, Fahrmann JF, Aguilar-Bonavides C, Villalobos P, Delgado O, Dhillon D, Dennison JB, Ostrin EJ, Wang H, Behrens C, Do KA, Gazdar AF, Hanash SM, Taguchi A. Role of CPS1 in Cell Growth, Metabolism, and Prognosis in LKB1-Inactivated Lung Adenocarcinoma. J Natl Cancer Inst 109(3):1-9, 2017. PMID: 28376202.
- Yang Q, Chen LS, Ha MJ, Do KA, Neelapu SS, Gandhi V. Idelalisib Impacts Cell Growth through Inhibiting Translation-Regulatory Mechanisms in Mantle Cell Lymphoma. Clin Cancer Res 23(1):181-192, 2017. e-Pub 2016. PMID: 27342398.
- An X, Hu J, Do KA. SIFORM: shared informative factor models for integration of multi-platform bioinformatic data. Bioinformatics 32(21):3279-3290, 2016. e-Pub 2016. PMID: 27381342.
- Tayob N, Do KA, Feng Z. Unbiased estimation of biomarker panel performance when combining training and testing data in a group sequential design. Biometrics 72(3):888-96, 2016. e-Pub 2016. PMID: 26845527.
- Jiang Y, Chen HC, Su X, Thompson PA, Liu X, Do KA, Wierda W, Keating MJ, Plunkett W. ATM function and its relationship with ATM gene mutations in chronic lymphocytic leukemia with the recurrent deletion (11q22.3-23.2). Blood Cancer J 6(6, e465):e465, 2016. e-Pub 2016. PMID: 27588518.
- Kebriaei P, Singh H, Huls MH, Figliola MJ, Bassett R, Olivares S, Jena B, Dawson MJ, Kumaresan PR, Su S, Maiti S, Dai J, Moriarity B, Forget MA, Senyukov V, Orozco A, Liu T, McCarty J, Jackson RN, Moyes JS, Rondon G, Qazilbash M, Ciurea S, Alousi A, Nieto Y, Rezvani K, Marin D, Popat U, Hosing C, Shpall EJ, Kantarjian H, Keating M, Wierda W, Do KA, Largaespada DA, Lee DA, Hackett PB, Champlin RE, Cooper LJ. Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells. J Clin Invest 126(9):3363-76, 2016. e-Pub 2016. PMID: 27482888.
- Caruso HG, Torikai H, Zhang L, Maiti S, Dai J, Do KA, Singh H, Huls H, Lee DA, Champlin RE, Heimberger AB, Cooper LJ. Redirecting T-Cell Specificity to EGFR Using mRNA to Self-limit Expression of Chimeric Antigen Receptor. J Immunother 39(5):205-17, 2016. PMID: 27163741.
- Kim J, Davis JW, Klein EA, Magi-Galluzzi C, Lotan Y, Ward JF, Pisters LL, Basler JW, Pettaway CA, Stephenson A, Li Ning Tapia EM, Efstathiou E, Wang X, Do KA, Lee JJ, Gorlov IP, Vornik LA, Hoque AM, Prokhorova IN, Parnes HL, Lippman SM, Thompson IM, Brown PH, Logothetis CJ, Troncoso P. Tissue Effects in a Randomized Controlled Trial of Short-term Finasteride in Early Prostate Cancer. EBioMedicine 7:85-93, 2016. e-Pub 2016. PMID: 27322462.
- Tayob N, Lok AS, Do KA, Feng Z. Improved Detection of Hepatocellular Carcinoma by Using a Longitudinal Alpha-Fetoprotein Screening Algorithm. Clin Gastroenterol Hepatol 14(3):469-475, 2016. e-Pub 2015. PMID: 26260109.
- Powell E, Shao J, Yuan Y, Chen HC, Cai S, Echeverria GV, Mistry N, Decker KF, Schlosberg C, Do KA, Edwards JR, Liang H, Piwnica-Worms D, Piwnica-Worms H. p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer. Breast Cancer Res 18(1):13, 2016. e-Pub 2016. PMID: 26818199.
- Chekouo T, Stingo FC, Guindani M, Do KA. A Bayesian predictive model for imaging genetics with application to schizophrenia. Annals of Applied Statistics 10(3):1547-1571, 2016.
- McAuliffe PF, Evans KW, Akcakanat A, Chen K, Zheng X, Zhao H, Eterovic AK, Sangai T, Holder AM, Sharma C, Chen H, Do KA, Tarco E, Gagea M, Naff KA, Sahin A, Multani AS, Black DM, Mittendorf EA, Bedrosian I, Mills GB, Gonzalez-Angulo AM, Meric-Bernstam F. Correction: Ability to Generate Patient-Derived Breast Cancer Xenografts Is Enhanced in Chemoresistant Disease and Predicts Poor Patient Outcomes. PLoS One 11(3):e0151121, 2016. e-Pub 2016. PMID: 26953790.
- Ha MJ, Baladandayuthapani V, Do KA. DINGO: Differential Network Analysis in Genomics. Bioinformatics 31(21):3413-3420, 2015. e-Pub 2015. PMID: 26148744.
- Wang Y, Hobbs BP, Hu J, Ng CS, Do KA. Predictive classification of correlated targets with application to detection of metastatic cancer using functional CT imaging. Biometrics 71(3):792-802, 2015. e-Pub 2015. PMID: 25851056.
- Chekouo T, Stingo FC, Doecke JD, Do KA. Incorporating microRNA regulatory network and pathways: a Bayesian graphical approach to the selection of miRNAs and genes with censored outcomes. Biometrics 71(2):428-38, 2015. e-Pub 2015. PMID: 25639276.
- Rembach A, Stingo FC, Peterson C, Vannucci M, Do KA, Wilson WJ, Macaulay SL, Ryan TM, Martins RN, Ames D, Masters CL, Doecke JD, AIBL Research Group. Bayesian graphical network analyses reveal complex biological interactions specific to Alzheimer's disease. J Alzheimers Dis 44(3):917-25, 2015. PMID: 25613103.
- Ha MJ, Baladandayuthapani V, Do KA. Prognostic gene signature identification using causal structure learning: applications in kidney cancer. Cancer Inform 14(Suppl 1):23-35, 2015. e-Pub 2015. PMID: 25861215.
- Tam CS, O'Brien S, Plunkett W, Wierda W, Ferrajoli A, Wang X, Do KA, Cortes J, Khouri I, Kantarjian H, Lerner S, Keating MJ. Life After FCR: Outcomes of patients with chronic lymphocytic leukemia who progress after frontline treatment with Fludarabine, Cyclophosphamide and Rituximab. Blood 124(20):3059-64, 2014. e-Pub 2014. PMID: 25281606.
- Hassan B, Akcakanat A, Sangai T, Evans KW, Adkins F, Eterovic AK, Zhao H, Chen K, Chen H, Do KA, Xie SM, Holder AM, Naing A, Mills GB, Meric-Bernstam F. Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors. Oncotarget 5(18):8544-57, 2014. e-Pub 2014. PMID: 25261369.
- Pande M, Bondy ML, Do KA, Sahin AA, Ying J, Mills GB, Thompson PA, Brewster AM. Association between germline single nucleotide polymorphisms in the PI3K-AKT-mTOR pathway, obesity, and breast cancer disease-free survival. Breast Cancer Res Treat 147(2):381-7, 2014. e-Pub 2014. PMID: 25108739.
- Zhang L, Baladandayuthapani V, Mallick BK, Manyam GC, Thompson PA, Bondy ML, Do KA. Bayesian hierarchical structured variable selection methods with application to MIP studies in breast cancer. J R Stat Soc Ser C Appl Stat 63(4):595-620, 2014. PMID: 25705056.
- Meric-Bernstam F, Akcakanat A, Chen H, Sahin A, Tarco E, Carkaci S, Adrada BE, Singh G, Do KA, Garces ZM, Mittendorf E, Babiera G, Bedrosian I, Hwang R, Krishnamurthy S, Symmans WF, Gonzalez-Angulo AM, Mills GB. Influence of Biospecimen Variables on Proteomic Biomarkers in Breast Cancer. Clin Cancer Res 20(14):3870-83, 2014. e-Pub 2014. PMID: 24895461.
- Blanco E, Sangai T, Wu S, Hsiao A, Ruiz-Esparza GU, Gonzalez-Delgado CA, Cara FE, Granados-Principal S, Evans KW, Akcakanat A, Wang Y, Do KA, Meric-Bernstam F, Ferrari M. Colocalized delivery of rapamycin and paclitaxel to tumors enhances synergistic targeting of the PI3K/Akt/mTOR pathway. Mol Ther 22(7):1310-9, 2014. e-Pub 2014. PMID: 24569835.
- Gonzalez-Angulo AM, Akcakanat A, Liu S, Green MC, Murray JL, Chen H, Palla SL, Koenig KB, Brewster AM, Valero V, Ibrahim NK, Moulder-Thompson S, Litton JK, Tarco E, Moore J, Flores P, Crawford D, Dryden MJ, Symmans WF, Sahin A, Giordano SH, Pusztai L, Do KA, Mills GB, Hortobagyi GN, Meric-Bernstam F. Open-label randomized clinical trial of standard neoadjuvant chemotherapy with paclitaxel followed by FEC versus the combination of paclitaxel and everolimus followed by FEC in women with triple receptor-negative breast cancer . Ann Oncol 25(6):1122-7, 2014. e-Pub 2014. PMID: 24669015.
- Doecke JD, Chekouo T, Stingo FC, and Do K-A. miRNA target gene identification: sourcing miRNA-target gene relationships for the analyses of TCGA Illumina miSeq and RNA-Seq Hiseq platform data. International Journal of Human Genetics 14(1):17-22, 2014.
- Chavez-Macgregor M, Liu S, De Melo-Gagliato D, Chen H, Do KA, Pusztai L, Fraser Symmans W, Nair L, Hortobagyi GN, Mills GB, Meric-Bernstam F, Gonzalez-Angulo AM. Differences in gene and protein expression and the effects of race/ethnicity on breast cancer subtypes. Cancer Epidemiol Biomarkers Prev 23(2):316-23, 2014. e-Pub 2013. PMID: 24296856.
- Gorlov IP, Yang JY, Byun J, Logothetis C, Gorlova OY, Do KA, Amos C. How to get the most from microarray data: advice from reverse genomics. BMC Genomics 15:223, 2014. e-Pub 2014. PMID: 24656147.
- Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML. Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer. Breast Cancer Res Treat 143(1):189-201, 2014. e-Pub 2013. PMID: 24305980.
- Shirazi F, Farmakiotis D, Yan Y, Albert N, Do KA, Kim-Anh D, Kontoyiannis DP. Diet modification and Metformin have a beneficial cial effect in a model of obesity and mucormycosis. PLoS One 9(9):e108635, 2014. e-Pub 2014. PMID: 25268492.
- León-Novelo LG, Müller P, Arap W, Sun J, Pasqualini R, Do KA. Bayesian decision theoretic multiple comparison procedures: an application to phage display data. Biom J 55(3):478-89, 2013. e-Pub 2012. PMID: 23281047.
- León-Novelo LG, Müller P, Arap W, Kolonin M, Sun J, Pasqualini R, Do KA. Semiparametric Bayesian Inference for Phage Display Data. Biometrics 69(1):174-83, 2013. e-Pub 2013. PMID: 23339534.
- Wang W, Baladandayuthapani V, Morris JS, Broom BM, Manyam G, Do KA. iBAG: integrative Bayesian analysis of high-dimensional multi-platform genomics data. Bioinformatics 29(2):149-59, 2013. e-Pub 2012. PMID: 23142963.
- Wang W, Baladandayuthapani V, Holmes CC, Do KA. Integrative network-based Bayesian analysis of diverse genomics data. BMC Bioinformatics 14 Suppl 13:S8, 2013. e-Pub 2013. PMID: 24267288.
- Bonato V, Baladandayuthapani V, Broom BM, Sulman EP, Aldape KD, Do KA. Bayesian ensemble methods for survival prediction in gene expression data. Bioinformatics 27(3):359-67, 2011. e-Pub 2010. PMID: 21148161.
- Zhang S, Mueller P, Do KA. A Bayesian Semiparametric Survival Model with Longitudinal Markers. Biometrics 66(2):435-43, 2010. e-Pub 2009. PMID: 19508243.
- Brewster AM, Do KA, Thompson PA, Hahn KM, Sahin AA, Cao Y, Stewart MM, Murray JL, Hortobagyi GN, Bondy ML. Relationship between epidemiologic risk factors and breast cancer recurrence. J Clin Oncol 25(28):4438-44. e-Pub 2007. PMID: 17785707.
- Ji Y, Yin G, Tsui K-W, Kolonin MG, Sun J, Arap W, Pasqualini R, Do K-A. Bayesian mixture models for complex high dimensional count data in phage display experiments. Journal of the Royal Statistical Society: Series C (Applied Statistics) 56(2):139-52, 2007.
- Do K-A, McLachlan GJ, Bean R, Wen S. Gene shaving versus mixture models for the clustering of microarray gene expression data. Cancer Informatics 2:25-43, 2007. PMID: No PubMed.
- Kim SJ, Uehara H, Yazici S, Busby JE, Nakamura T, He J, Maya M, Logothetis C, Mathew P, Wang X, Do KA, Fan D, Fidler IJ. Targeting platelet-derived growth factor receptor on endothelial cells of multidrug-resistant prostate cancer. J Natl Cancer Inst 98(11):783-93, 2006. PMID: 16757703.
- Do K-A Mueller P, Tang F. A Bayesian mixture model for differential gene expression. Journal of the Royal Statistical Society, Series C-Applied Statistics 54(3):1-18, 2005. PMID: No PubMed.
- Do KA, Johnson MM, Lee JJ, Wu XF, Dong Q, Hong WK, Khuri FR, Spitz MR. Longitudinal study of smoking patterns in relation to the development of smoking-related secondary primary tumors in patients with upper aerodigestive tract malignancies. Cancer 101(12):2837-42, 2004. PMID: 15536619.
- Do K-A, Green A, Guthrie JR, Dudley EC, Burger HG, Dennerstein L. Longitudinal study of risk factors for coronary heart disease across the menopausal transition. Am J Epidemiol 151:584-93, 2000. PMID: 10733040.
- Do K-A, Kirk K. Discriminant analysis of event-related potential curves using smoothed principal components. Biometrics 55:174-81, 1999. PMID: 11318152.
- Wood ATA, Do K-A, Broom BM. Sequential linearization of empirical likelihood constraints with application to U-statistics. Journal of Computational and Graphical Statistics 5:365-85, 1996.
- Booth JG, Do K-A. Simple and efficient methods for constructing bootstrap confidence intervals. Computational Statistics 8:333-46, 1994.
- Do K-A, Hall P. Distribution estimation using concomitants of order statistics, with application to Monte Carlo stimulation for the bootstrap. Journal of the Royal Statistical Society, Series B 54:1-14, 1992.
- Do K-A, Hall P. On importance sampling for the bootstrap. Biometrika 78:161-167, 1991.
- Do K-A, McLachlan GJ. Estimation of mixing proportions: a case study. Applied Statistics 33:134-40, 1984.
Book Chapters
- Huang X, Do K-A. Commentary on: A novel case-control design to estimate the extent of overdiagnosis of breast cancer due to organised population-based mammography screening. In: Breast Diseases: A Year Book Quarterly, 211-214, 2015.
- Broom BM, Do K-A, Bondy M, Thompson P, Coombes K. Methods for the analysis of copy number data in cancer research. In: Advances in Statistical Bioinformatics: Models and Integrative Inferences for High-Throughput Data. Cambridge University Press, 2013.
- Wang W, Baladandayuthapani V, Broom BM, Do K-A. Bayesian graphical models for integrating multi-platform genomics data. Methods for the analysis of copy number data in cancer research. In: Advances in Statistical Bioinformatics: Models and Integrative Inferences for High-Throughput Data. Cambridge University Press, 2013.
- Wang W, Baladandayuthapani V, Broom BM,Do K-A. Bayesian graphical models for multi-platform high-dimensional data. In: Advances in Statistical Bioinformatics: Models and Integrative Inference for High-Throughput Data. Cambridge University Press, 2013.
Books (edited and written)
- Do K-A, Qin Z, Vannucci M.. Advances in Statistical Bioinformatics: Models and Integrative Inferences for High-Throughput Data. Cambridge University Press, 2013.
- Do K-A, Müller P, Vannucci M. Bayesian Inference for Gene Expression and Proteomics. Cambridge University Press, 456, 2006.
- McLachlan GJ, Do K-A, Ambroise C. Analyzing Microarray Gene Expression Data. In: Wiley Series in Probability and Statistics. Wiley-Interscience: New Jersey, 352, 2004.
Grant & Contract Support
| Title: | Center for Clinical and Translational Sciences (PP-2) |
| Funding Source: | NIH/NCI (Subcontract from the UT Health Science Center - Houston) |
| Role: | Collaborator - Statistical Leader |
| Title: | Risk Prediction for ER Negative Breast Cancer Recurrence |
| Funding Source: | NIH/NCI (Subcontract from Baylor College of Medicine) |
| Role: | Co-Investigator |
| Title: | Chronic Lymphocytic Leukemia Research Consortium (Core B) |
| Funding Source: | NIH/NCI (via Subaward agreement University of California San Diego) |
| Role: | Core Leader |
| Title: | Cancer Center Support Grant (CCSG) - Biostatistics Resource Group (BRG) |
| Funding Source: | NIH/NCI |
| Role: | Biostatistician |
| Title: | AML / MDS Flagship 1 Moonshot Program |
| Funding Source: | MD Anderson Cancer Center Moonshot |
| Role: | Biostatistics Director |
| Title: | Prostate Cancer Flagship 2 Moonshot Program |
| Funding Source: | MD Anderson Cancer Center Moonshot Flagships |
| Role: | Biostatistics Director |
| Title: | Defining and treating targetable lesions in AYA acute lymphoblastic leukemia |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-Investigator |
| Title: | MD Anderson Cancer Center Prostate Cancer SPORE. Core 1: Biostatistics & Bioinformatics Core |
| Funding Source: | NIH/NCI |
| Role: | Co-Director |
| Title: | The Early Detection Research Network: Data Management and Coordination Center |
| Funding Source: | Subaward from Fred Hutchinson Cancer Research Center/NIH/NCI |
| Role: | Co-Investigator |
| Title: | Acute Myeloid Leukemia in the Immunosuppressed Microenvironment - CPRIT MIRA Core 3 - Biostatistics/Bioinformatics |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Core Director |
| Title: | AML / MDS Flagship 3 Moonshot Project |
| Funding Source: | MD Anderson Cancer Center Moonshot |
| Role: | Biostatistician |
| Title: | Integration of Clinical Epidemiology and Metagenomics to Develop Models Which Predict Colonization and Infectious Outcomes by Antibiotic Resistant Organisms |
| Funding Source: | NIH |
| Role: | Co-Primary Mentor |
| Title: | Longitudinal Proteomic and Metabolomic Predictors of Pancreatic Cyst Malignant Progression and Early State Pancreatic Cancer |
| Funding Source: | NIH/NCI via Subaward Indiana University |
| Role: | Co-Investigator |
| Title: | Moon Shot Project 2: Biology and Targeting of 17pdel and mutant TP53 in CLL |
| Funding Source: | The University of Texas MD Anderson Cancer Center |
| Role: | Co-Investigator |
| Title: | Moon Shot Project 3: Targeting Pathophysiology of CLL |
| Funding Source: | The University of Texas MD Anderson Cancer Center |
| Role: | Co-Investigator |
| Title: | REFLECT: Recurrent Features Leveraged for Combination Therapy |
| Funding Source: | NIH/NCI |
| Role: | Co-Investigator |
| Title: | RP230051 - Role of Ataxia Telangiectasia Mutated in mitochondrial autophagy in Cancer |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-Investigator |
Patient Reviews
CV information above last modified August 28, 2024