Skip to Content

'
Kim-Anh Do

Present Title & Affiliation

Primary Appointment

Professor, Department of Biostatistics, Division of Quantitative Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Adjunct Professor, Statistics, Rice University, Houston, TX
Adjunct Professor, Statistics, Texas A&M University, College Station, TX

Bio Statement

Kim-Anh Do, Ph.D., is a Professor in the Department of Biostatistics at M. D. Anderson, and a recipient of the Faculty Scholar Award at M. D. Anderson in 2003. She is a Fellow of the American Statistical Association and the Royal Statistical Society. She has served as a primary statistician or co-investigator on several National Institutes of Health (NIH) funded grants and clinical trials in prostate cancer, epidemiology, leukemia, upper aerodigestive cancer, breast cancer and brain cancer, including the Early Detection Research Network (EDRN) grant, the Prostate SPORE (as Director of the Biostatistics Core), the Breast SPORE, and the Brain SPORE at M. D. Anderson. She has significant publications in statistical methodology, computing, biomedical, and in other applied specialist journals. Her most recent interest is in the development of clustering and analytic methods for genomic and proteomic expressions. She has developed bioinformatics software and authored books: (i) Analyzing microarray gene expression data; (ii) Bayesian Inference for Gene Expression and Proteomics. Her extensive contribution to statistical and cancer research at M.D. Anderson has resulted in more than 130 published articles in the past years. Additional information regarding Dr. Do's educational and professional activities can be found here.

Research Interests

  • Computational Statistics and Biostatistics
  • Bioinformatics
  • Statistical Genetics
  • Non-parametric Statistical Methods

Office Address

The University of Texas MD Anderson Cancer Center
Department of Biostatistics
1400 Pressler Street
Unit Number: 1411
Houston, TX 77030
Room Number: FCT4.6040
Phone: (713) 794-4155
Fax: (713) 563-4243
Email: kim@mdanderson.org

Education & Training

Degree-Granting Education

1990 Stanford University, Stanford, CA, PHD, Statistics
1985 Stanford University, Stanford, CA, MS, Statistics
1983 Queensland University, Brisbane, Australia, B.Sc., First Class Honors, Mathematics and Computer Science

Honors and Awards

2006 Fellow, American Statistical Association
2005 Fellow, Royal Statistical Society
2003 Faculty Scholar Award, University of Texas M.D. Anderson Cancer Center
1994 Australian Academy of Science Travel Award
1983 Amy R. Hughes Award, Australian Federation of University Women, Australia
1982 Caltex Woman Graduate of the Year, Postgraduate Scholarship, University of Queensland

Professional Memberships

American Statistical Association, Houston Chapter (HACASA), Houston, TX
President, 2003-2004
President-Elect, 2002-2003

Selected Publications

Peer-Reviewed Original Research Articles
1. Tsavachidou D, McDonnell TJ, Wen S, Wang X, Vakar-Lopez F, Pisters LL, Pettaway CA, Wood CG, Do KA, Thall PF, Stephens C, Efstathiou E, Taylor R, Menter DG, Troncoso P, Lippman SM, Logothetis CJ, Kim J. Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer. J Natl Cancer Inst 101(5). e-Pub 2/2009. PMID: 19244175.
2. McDonnell TJ, Chari NS, Cho-Vega JH, Troncoso P, Wang X, Bueso-Ramos CE, Coombes K, Brisbay S, Lopez R, Prendergast G, Logothetis C, Do KA. Biomarker expression patterns that correlate with high grade features in treatment naive, organ-confined prostate cancer. BMC Med Genomics 1:1, 2008. PMCID: PMC2227949.
3. Brewster AM, Do KA, Thompson PA, Hahn KM, Sahin AA, Cao Y, Stewart MM, Murray JL, Hortobagyi GN, Bondy ML. Relationship between epidemiologic risk factors and breast cancer recurrence. J Clin Oncol 25(28). e-Pub 9/2007. PMID: 17785707.
4. Ji Y, Yin G, Tsui K-W, Kolonin MG, Sun J, Arap W, Pasqualini R, Do K-A. Bayesian mixture models for complex high dimensional count data in phage display experiments. Journal of the Royal Statistical Society: Series C (Applied Statistics) 56(2):139-52, 3/2007.
5. Do K-A, McLachlan GJ, Bean R, Wen S. Gene shaving versus mixture models for the clustering of microarray gene expression data. Cancer Informatics 2:25-43, 2007. PMID: No PubMed.
6. Do K-A Müller P, Tang F. A Bayesian mixture model for differential gene expression. Journal of the Royal Statistical Society, Series C-Applied Statistics 54(3):1-18, 2005. PMID: No PubMed.
7. Do KA, Johnson MM, Lee JJ, Wu XF, Dong Q, Hong WK, Khuri FR, Spitz MR. Longitudinal study of smoking patterns in relation to the development of smoking-related secondary primary tumors in patients with upper aerodigestive tract malignancies. Cancer 101(12):2837-42, 12/2004. PMID: 15536619.
8. Do K-A, Green A, Guthrie JR, Dudley EC, Burger HG, Dennerstein L. Longitudinal study of risk factors for coronary heart disease across the menopausal transition. Am J Epidemiol 151:584-93, 3/2000. PMID: 10733040.
9. Do K-A, Kirk K. Discriminant analysis of event-related potential curves using smoothed principal components. Biometrics 55:174-81, 3/1999. PMID: 11318152.
10. Wood ATA, Do K-A, Broom BM. Sequential linearization of empirical likelihood constraints with application to U-statistics. Journal of Computational and Graphical Statistics 5:365-85, 1996.
11. Booth JG, Do K-A. Simple and efficient methods for constructing bootstrap confidence intervals. Computational Statistics 8:333-46, 1994.
12. Do K-A, Hall P. Distribution estimation using concomitants of order statistics, with application to Monte Carlo stimulation for the bootstrap. Journal of the Royal Statistical Society, Series B 54:1-14, 1992.
13. Do K-A, Hall P. On importance sampling for the bootstrap. Biometrika 78:161-167, 1991.
14. Do K-A, McLachlan GJ. Estimation of mixing proportions: a case study. Applied Statistics 33:134-40, 1984.
15. Wang X, Baladandayuthapani V, Mallick BK, Do K-A. Bayesian flexible joint modeling for survival and c urve predictors with application to prostate cancer. Biostatistics (2009). Submitted.

Book Chapters
1. Broom BM, Do K-A. Building networks with microarray data. In: Statistical Methods in Molecular Biology (2009. Ed(s) Bang H, Zhou XK, Van Epps HL, Mazumdar M. Humana Press. Submitted.

Books (edited and written)
1. Do K-A, Müller P, Vannucci M. Bayesian Inference for Gene Expression and Proteomics. Cambridge University Press, 2006. PMID: 052186092X.
2. McLachlan GJ, Do K-A, Ambroise C. Analyzing Microarray Gene Expression Data. In: Wiley Series in Probability and Statistics. Wiley-Interscience: New Jersey, 2004. PMID: 0471226165.

Grant & Contract Support

Title: University of Texas SPORE in Prostate Cancer (PC-B)
Funding Source: NIH/NCI
Role: Core Director
Principal Investigator: Cristopher J. Logothetis
Duration: 9/2/2009 - 8/31/2014
 
Title: Integration of Vascular Genomics and Proteomics for Diagnosis and Therapy of Cancer
Funding Source: NIH/NCI
Role: Senior Investigator
Principal Investigator: Renata Pasqualini
Duration: 9/8/2008 - 8/31/2011
 
Title: SPORE in Brain Cancer (PP-3A)
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: W. K. Alfred Yung
Duration: 9/1/2008 - 8/31/2013
 
Title: Cancer Center Support Grant - Biostatistics Shared Resource (PPSR-21)
Funding Source: NIH/NCI
Role: Investigator
Principal Investigator: John Mendelsohn
Duration: 7/1/2008 - 6/30/2013
 
Title: Host risk factors and activation of the AKT and mammalian target of rapamycin (mTor) signaling pathway in breast cancer
Funding Source: UTMDACC- Breast SPORE IRG
Role: Statistician
Principal Investigator: Abenaa Brewster
Duration: 4/30/2008 - 3/31/2010
 
Title: Comparative Study of Breast Cancers and their risk factors among Mexican women in Mexico and United States
Funding Source: AVON Foundation
Role: Co-Investigator
Principal Investigator: Melissa Bondy
Duration: 9/1/2007 - 3/31/2010
 
Title: A multigene predictor for individualization of patient treatment in newly diagnosed glioblastoma
Funding Source: V Foundation for Cancer Research
Role: Biostatistician
Principal Investigator: Kenneth Aldape
Duration: 9/1/2007 - 8/31/2008
 
Title: Insulin Resistance and Breast Cancer Outcome
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Abenna Brewster
Duration: 7/1/2007 - 6/30/2009
 
Title: UT Health Science Center - Center for Clinical and Translational Sciences - (PP-4)
Funding Source: NIH/NCRR
Role: Biostatistician
Principal Investigator: David McPherson
Duration: 9/1/2006 - 6/30/2011
 
Title: University of Texas M. D. Anderson Cancer Center SPORE in Prostate Cancer Biostatistics and Bioinformatics Core (PC-B)
Funding Source: NIH/NCI
Role: Core Director
Principal Investigator: Christopher J. Logothetis
Duration: 1/1/2006 - 12/31/2007
 
Title: UTMDACC SPORE in Breast Cancer (PC-B)
Funding Source: NIH/NCI
Role: Investigator
Principal Investigator: Gabriel Hortobagyi
Duration: 9/23/2005 - 11/1/2010
 
Title: Chronic Lymphocytic Leukemia Research Consortium (PC-B)
Funding Source: NIH/NCI (Subcontract from University of California San Diego)
Role: Core Director
Principal Investigator: Thomas J. Kipps
Duration: 5/1/2000 - 4/30/2011

Last updated: 11/5/2010