Lumarie Santiago, M.D.
Department of Breast Imaging, Division of Diagnostic Imaging
About Dr. Lumarie Santiago
Lumarie Santiago joined the Breast Imaging Section in 2007 following her residency at The University of Texas – Health Science Center at Houston and fellowship at The University of Texas MD Anderson Cancer Center. In addition to excellence in clinical and educational activities, Dr. Santiago has authored and co-authored peer-reviewed and invited articles, abstracts and book chapters.
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Present Title & Affiliation
Primary Appointment
Professor, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
Minimally invasive percutaneous breast interventions
Advanced breast imaging techniques
Clinical Interests
Molecular breast imaging
Digital Breast Tomosynthesis
Breast MRI
Minimally invasive percutaneous breast interventions
Education & Training
Degree-Granting Education
| 2001 | University of Puerto Rico, Rio Piedras, PR, US, MD |
| 1997 | University of Puerto Rico, Rio Piedras, PR, US, Biology, BS |
Postgraduate Training
| 2006-2007 | Clinical Fellowship, Breast Imaging, Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2002-2006 | Clinical Residency, Diagnostic Radiology Residency, University of Texas Houston Health Science Center, Houston, TX |
| 2001-2002 | Clinical Internship, Transitional Intern Year, San Juan Bautista Medical Center, Caguas, PR |
Licenses & Certifications
| 2007 | Texas Medical Board Physician's Permit |
| 2006 | American Board of Radiology (MOC) |
Experience & Service
Faculty Academic Appointments
Associate Professor, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2020
Associate Professor, Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2019
Assistant Professor, Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2006 - 2013
Administrative Appointments/Responsibilities
Chair, RSNA 3D Printing Special Interest Group, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - Present
Vice Chair, RSNA 3D Printing Special Interest Group, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - 2023
Proxy, CMD Proxy, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - Present
Course Coordinator, RSNA 3D Printing Symposium 2022, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - Present
BID Awards & Recognition Team, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2021 - Present
Committee Member, 3D Printing Registry By ACR, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - Present
Co-Medical Director, Anatomic 3D Printing and Visualization Program, Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, 2018 - Present
Nellie B. Connally Lead Interpreting Physician, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - 2017
Section Chief Ad Interim, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - 2015
Lead Physician, West Houston Imaging Facility Design Committee, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2012 - 2014
Chair, Breast Imaging Visiting Professor Lectureship, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2020
Co-Chair, Quality Assurance Interesting Conference, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - Present
Carestream Mammo Module Advisor, Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2009 - 2012
Screening Mammography Quality Assurance Project, The University of Texas MD Anderson Cancer Center, Houston, TX, 2008 - 2009
Breast Imaging Teaching File Coordinator, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2008 - 2014
Director, Breast Imaging Observership Program, Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 2008 - Present
Other Professional Positions
Memorial Hermann Breast Imaging Protocol Standardization, Memorial Hermann, Houston, TX, 2014 - 2015
Breast Imaging Reporting Standardization Committee, Memorial Hermann, Houston, TX, 2014 - 2015
Founder, Breast Imaging Club of Houston, Houston, TX, 2011 - 2012
Extramural Institutional Committee Activities
Senior Clinical Faculty, Search Advisory Committee Deputy Division Head - Operations Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Breast Imaging Department Awards Committee, The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Alternative Technologies for COVID-19 Task Force, The University of Texas MD Anderson Cancer Center, 2020 - Present
Member, PPE Prototype Task Force, IDEAS Lab, The University of Texas MD Anderson Cancer Center, 2020 - Present
Member, DIY PPE Task Force, Strategy & Innovation, The University of Texas MD Anderson Cancer Center, 2020 - 2020
Member, Screening Mammography Technical Recall Quality Assurance Committee, The University of Texas MD Anderson Cancer Center, 2017 - Present
Member, Faculty Achievement Award Committee Faculty Senate- Patient Care, The University of Texas MD Anderson Cancer Center, 2017 - Present
Faculty Representative, Cross-Functional Intervention and Transformation Team (XFITT) Committee, The University of Texas MD Anderson Cancer Center, 2016 - 2019
Member, Faculty Senate Elections Committee, The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, Main Campus Breast Imaging Clinical Rotation Management Committee, The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, Clinical Research Advisory Committee, The University of Texas MD Anderson Cancer Center, 2015 - Present
Member, Diagnostic Radiology Faculty Merit Committee, The University of Texas MD Anderson Cancer Center, 2015 - 2016
Breast Imaging Faculty Contact, Diagnostic Imaging Physician Website Committee, The University of Texas MD Anderson Cancer Center, 2015
Member, Breast Imaging Penrad Report Template and Database Committee, The University of Texas MD Anderson Cancer Center, 2015 - Present
PQI Lead, Ultrasound-guided Breast Fine Needle Aspiration (FNA) Non-diagnostic Rates, The University of Texas MD Anderson Cancer Center, 2015 - 2017
Chair, Diagnostic Imaging-Council on Gender Inclusiveness (DI-COGI) Work-life Balance Subcommittee, The University of Texas MD Anderson Cancer Center, 2014 - 2016
Member, Breast Imaging MagView Report Template and Database Committee, The University of Texas MD Anderson Cancer Center, 2014 - Present
Breast Imaging Representative, Clinical Functional Committee, The University of Texas MD Anderson Cancer Center, 2014 - 2017
Member, Executive Committee Faculty Senate, The University of Texas MD Anderson Cancer Center, 2014 - 2016
Member, Association of University Radiologist Scientific Program, The University of Texas MD Anderson Cancer Center, 2014 - 2020
Breast Imaging Section Representative, Ad Hoc Maintenance of Certification Committee, The University of Texas MD Anderson Cancer Center, 2013 - 2016
Member, Centralization and Expansion of Breast Imaging and Cancer Prevention Design Committee, The University of Texas MD Anderson Cancer Center, 2012 - 2012
Member, Faculty Senate Education, The University of Texas MD Anderson Cancer Center, 2011 - Present
Member, Faculty Senate Academic Affairs, The University of Texas MD Anderson Cancer Center, 2011 - Present
Member, Radiologist Transcriptionist Worklist, The University of Texas MD Anderson Cancer Center, 2011 - 2013
Breast Imaging Representative, Diagnostic Imaging Informatics Advisory Group, The University of Texas MD Anderson Cancer Center, 2011 - 2013
Breast Imaging Representative, Structured Reporting Group, The University of Texas MD Anderson Cancer Center, 2010 - 2013
Honors & Awards
| 2024 | SBI Fellowship, Society Breast Imaging |
| 2019 | Certificate of Merit, American Roentgen Ray Society Scientific Program |
| 2019 | Bronze Medal, American Roentgen Ray Society Scientific Program |
| 2018 | Cum Laude Award - Educational Exhibit, Radiological Society of North America Annual Meeting |
| 2015 | Certificate of Merit - Education Exhibit, Radiological Society of North America Annual Meeting |
| 2013 | Agfa Radiology Management Program, Association of University Radiologists |
| 2012 | Clinician Educator Development Program, American Roentgen Ray Society Scientific Program |
| 2012 | Phillips Faculty Development Program, Association of University Radiologists |
| 2006 | Outstanding Interesting Case File Fourth Year Resident: Intraductal papillary mucinous neoplasia, The University of Texas Houston Health Science Center |
| 2006 | First Place, 15th Annual Kay Vydareny Film Interpretation Competition, Association of University Radiologists |
| 2005 - 2006 | Chief Resident, Diagnostic Radiology, The University of Texas Houston Health Science Center |
Selected Presentations & Talks
Local Presentations
- 2026. Calcifications by mammography. Invited. 9th Annual Breast Imaging Seminar. Houston, TX, US.
- 2025. Breast microcalcifications - Descriptors & their predictive value. Invited. 8th Annual Breast Imaging Seminar. Houston, TX, US.
- 2025. Tips & Tricks for ultrasound guided biopsies. Invited. 8th Annual Breast Imaging Seminar. Houston, TX, US.
- 2024. MRI/CT Directed and Staging Ultrasound. Invited. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2020. Onco-Engineering virtual panel-3D printing in oncology. Conference. Texas A&M-MD Anderson Cancer Center. Houston, TX, US.
- 2020. MRI-guided biopsy troubleshooting. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2019. MRI-guided breast biopsy troubleshooting. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2019. Pre-procedure management: Patient preparation and device selection. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2018. Breast ultrasound: Pearls and pitfalls. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2014. Breast ultrasound: Pearls and pitfalls. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2014. Workshop: Percutaneous breast interventions. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2014. Pre-procedure management: Patient preparation and device selection. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2013. Workshop: Percutaneous breast interventions. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2012. Ultrasound innovations: Contrast enhanced ultrasound. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2012. Breast ultrasound cases. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2012. Breast ultrasound: Lesion characterization & management. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2010. Workshop: Digital mammography interpretation at the workstation. Conference. Houston Radiological Society. Houston, TX, US.
- 2009. Workshop: Ultrasound guided biopsy. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2009. Breast ultrasound and ACR BIRADS lexicon. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2009. Ultrasound in staging breast cancer. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
Regional Presentations
- 2026. Building a 3D space. Invited. RSNA Medical 3D Printing & Immersive Reality in Practice. Chicago, ILL, US.
- 2026. How to financially sustain 3D printing efforts. Invited. RSNA Medical 3D Printing & Immersive Reality in Practice. Chicago, ILL, US.
National Presentations
- 2025. Evolution of advanced 3D visualization: Choose your own adventure. Invited. Radiological Society of North America Annual Meeting RSNA 3D Printing Special Interest Group. Chicago, IL, US.
- 2025. RSNA hands-on lab: Next-gen netter: Harnessing 3D technology to bring anatomy to life for radiology residents and faculty. Invited. Radiology Society of North America Scientific Assembly. Chicago, IL, US.
- 2025. The radiologist's role in advancing 3D printing in healthcare. Invited. Radiological Society of North America Annual Meeting. Chicago, IL, US.
- 2023. Mistakes are meant for learning, not repeating: Analysis of technical repeat studies in screening mammography. Conference. 32nd Annual Interdisciplinary Breast Center Conference. Las Vegas, NV, US.
- 2022. Initial report of case characteristics from the RSNA-ACR 3D printing. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2022. To freeze or not to freeze? That is the question: Cryoablation for the treatment of breast cancer. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2022. 3D Printing and digital surgical rehearsal in complex spine surgery. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2021. 3D Printing: Clinical Applications. Invited. Radiological Society of North America Scientific Assembly 3D Printing Special Interest Group. Chicago, IL, US.
- 2021. 3D printing registry: An open discussion on getting started and submitting data. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2020. Assessment of early response to neoadjuvant systemic therapy (NAST) in triple-negative breast cancer (TNBC) using chemical exchange saturation transfer (CEST) MRI: Pilot study. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2020. Radiomic phenotypes from ultrafast dynamic contrast enhanced (DCE) MRI for prediction of the treatment response to neoadjuvant systemic therapy (NAST) of triple negative breast cancer (TNBC). Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2020. BI-RADS ultrasound lexicon descriptors and tumor-infiltrating lymphocytes in triple negative breast cancer. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2020. Reliability of pharmacokinetic (PK) parameters by DCE-MRI for prediction of neoadjuvant systemic treatment (NAST) response in triple negative breast cancer (TNBC) patients: A comparison of three analysis methods. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2020. Radiomic features of quantitative apparent diffusion coefficient (ADC) maps from peritumoral regions (PTRs) as predictors of early treatment response to neoadjuvant systemic therapy (NAST) in triple negative breast cancer (TNBC). Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2020. Comparison of chemical exchange saturation transfer (CEST) MRI acquisition and analysis for early neoadjuvant systemic therapy (NAST) treatment response assessment in triple negative breast cancer (TNBC). Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2020. Longitudinal MR imaging findings in triple negative breast cancer (TNBC) patients undergoing neoadjuvant systemic therapy (NAST) stratified by tumor infiltrating lymphocytes (TIL) levels. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2019. 3D printing in breast cancer: defining disease, enhancing surgical planning and patient satisfaction. Invited. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2019. Quantitative apparent diffusion coefficient (ADC) radiomics of tumor and peritumoral regions as potential predictors of treatment response to neoadjuvant chemotherapy (NACT) in triple negative breast cancer (TNBC) patients. Conference. San Antonio Breast Cancer Symposium. San Antonio, TX, US.
- 2019. Radiomics of quantitative apparent diffusion coefficient (ADC) from fibroglandular tissue (FGT) for prediction of tumor infiltrating lymphocytes (TIL) levels and neoadjuvant chemotherapy treatment (NACT) response in triple negative breast cancer (TNBC). Conference. San Antonio Breast Cancer Symposium. San Antonio, TX, US.
- 2019. Benign mimickers of breast malignancy. Conference. American Roentgen Ray Society Annual Meeting. Honolulu, HI, US.
- 2019. Beyond invasive ductal carcinoma: A review of unusual breast malignancies. Conference. American Roentgen Ray Society Annual Meeting. Honolulu, HI, US.
- 2019. Three-dimensional printed breast models as a novel teaching tool for learning BI-RADS in breast MRI. Conference. Association of University Radiologists. Baltimore, MD, US.
- 2018. Intraoperative use of three-dimensional printed breast models in the setting of breast cancer. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2017. Prediction of tumor response to neoadjuvant chemotherapy in breast cancer patients using quantitative Tc99m Sestamibi molecular breast imaging: Preliminary results. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2017. The benign shrinking breast. Conference. American Roentgen Ray Society Annual Meeting. New Orleans, LA, US.
- 2016. Neoplastic seeding in the setting of percutaneous image guided breast biopsies. Invited. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2014. Mastering the challenges of magnetic resonance imaging-guided breast interventions: Magnetic resonance imaging-guided biopsy and beyond. Invited. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
- 2010. Monitor zooming and detection of microcalcifications on digital screening mammograms. Conference. American Roentgen Ray Society Annual Meeting. San Diego, CA, US.
- 2005. Film Panel. Invited. Association of University Radiologists. Montreal, Quebec, Canada.
- 2003. Association of university radiologists 12th annual kay vydareny film interpretation competition moderator, case researcher and coordinator. Conference. Association of University Radiologists. Miami, FL, US.
- 2001. Epididymitis in children: Frequency and validation of color doppler ultrasonography as a diagnostic study. Conference. Radiological Society of North America Scientific Assembly. Chicago, IL, US.
Selected Publications
Peer-Reviewed Articles
- Rao, SH, Harris, J, Santiago, L, Brown, PD, Bird, JE, Tappa, KK. A Retrospective Time and Value Analysis of Surgical Oncology Cases Using 3D Printing. Bioengineering 12(8), 2025. e-Pub 2025. PMID: 40868334.
- Huang ML, Lane DL, Chang Sen LQ, Candelaria RP, Kuerer HM, Hunt KK, Akay C, Lim B, Shaitelman S, Hwang RF, Chen H, Katta R, Santiago L. Defining breast cryoablation treatment success: A guide for the curative and palliative treatment of breast cancer. Acad Radiol 31(12):4759-4771, 2024. e-Pub 2024. PMID: 39107186.
- Wang KC, Ryan JR, Chepelev L, Wake N, Quigley EP, Santiago L, Wentworth A, Alexander A, Morris JM, Fleischmann D, Ballard DH, Ravi P, Hirsch JD, Sturgeon GM, Huang YH, Decker SJ, Von Windheim N, Pugliese RS, Hidalgo RV, Patel P, Colon J, Thieringer FM, Rybicki FJ. Demographics, utilization, workflow and outcomes based on observational data from the RSNA-ACR 3D Printing Registry. J Am Coll Radiol 21(11):1781-1791, 2024. e-Pub 2024. PMID: 39117182.
- Huang ML, Lane DL, Santiago L. MRI-guided breast cryoablation with the patient in prone position. American Journal of Roentgenology (AJR) 4(4), 2024. e-Pub 2024. PMID: 38353451.
- Tappa K, Bird JE, Arribas EM, Santiago L. Multimodality Imaging for 3D Printing and surgical rehearsal in complex spine surgery. RadioGraphics 44(3), 2024. e-Pub 2024. PMID: 38386600.
- Garber HR, Basu S, Jindal S, He Z, Chu K, Raghavendra AS, Yam C, Santiago L, Adrada BE, Sharma P, Mittendorf EA, Litton JK. Durvalumab and tremelimumab before surgery in patients with hormone receptor positive, HER2-negative stageII-III breast cancer. Oncotarget 19(15):238-247, 2024. e-Pub 2024. PMID: 38502947.
- Basho RK, Zhao L, White JB, Huo L, Bassett RL, Mittendorf EA, Thompson A, Litton JK, Ueno N, Arun B, Lim B, Valero V, Tripathy D, Zhang J, Adrada BE, Santiago L, Ravenberg E, Seth S, Yam C, Moulder SL, Damodaran S. Comprehensive analysis identifies variability in PI3K pathway alterations in triple-negative breast cancer subtypes. JCOS Precis Oncol 8, 2024. e-Pub 2024. PMID: 38484209.
- Arribas, E, Kelil, T, Santiago, L, Ali, A, Chadalavada, SC, Chepelev, L, Ghodadra, A, Ionita, C, Lee, J, Ravi, P, Ryan, J, Sheikh, AM, Rybicki, FJ, Ballard, DH. Radiological Society of North America (RSNA) 3D Printing Special Interest Group (SIG) clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination. 3D Printing in Medicine 9(1), 2023. e-Pub 2023. PMID: 36952139.
- Lee, J, Chadalavada, SC, Ghodadra, A, Ali, A, Arribas, E, Chepelev, L, Ionita, C, Ravi, P, Ryan, J, Santiago, L, Wake, N, Sheikh, AM, Rybicki, FJ, Ballard, DH. Clinical situations for which 3D Printing is considered an appropriate representation or extension of data contained in a medical imaging examination. 3D Printing in Medicine 9(1), 2023. e-Pub 2023. PMID: 38032479.
- Lee J, Chadalavada SC, Ghodadra A, Ali A, Arribas M, Chepelev L, Ionita CN, Ravi P, Ryan JR, Santiago L, Wake N, Sheikh AM, Rybicki FJ, Ballard DH. Clinical situations for which 3D Printing is considered an appropriate representation or extension of data contained in a medical imaging examination: vascular conditions. 3D Printing in Medicine 9(1):34, 2023. e-Pub 2023. PMID: 38032479.
- Chen H, Ding Q, Khazai L, Damodaran S, Litton J, Rauch GM, Yam C, Chang JT, Seth S, Lim B, Adrada BE, Virani K, Song X, Candelaria RP, Arun BK, Santiago L, Saleem S, Abouharb S, Murthy RK, Ibrahim NK, Routbort MJ, Sahin AA, Valero V, Symmans WF, Tripathy D, Wang WL, Moulder S. PTEN in triple-negative breast carcinoma: protein expression and genomic alteration in pretreatment and posttreatment specimens. Ther Adv Med Oncol 15, 2023. e-Pub 2023. PMID: 37547448.
- Huang ML, Tomkovich K, Lane DL, Katta R, Candelaria RP, Santiago L. Breast cancer cryoablation fundamentals past and present: Technique optimization and imaging pearls. Acad Radio 30(10):2383-2395, 2023. e-Pub 2023. PMID: 37455177.
- Martaindale, S, Moseley, T, Santiago, L, Huang, ML, Sullivan, CR, Bassett Jr, R, Whitman, GJ. Analysis of Technical Repeat Studies in Screening Mammography. Journal of Breast Imaging 5(4):416-424, 2023. e-Pub 2023. PMID: 37520155.
- Martaindale S, Moseley TW, Santiago L, Huang M, Sullivan C, Bassett RL, Whitman GJ. Analysis of technical repeat studies in screening mammography. J Breast Imaging 5(4):416-424, 2023. e-Pub 2023.
- Abuhadra N, Sun R, Yam, Rauch GM, Ding Q, Lim B, Thompson A, Mittendorf EA, Adrada B, Damodaran S, Virani K, White J, Ravenberg E, Sun J, Choi J, Candelaria R, Arun B, Euno NT, Satiago L, Saleem S, Abouhsrb S, Murthy RK, Ibrahim N, Sahin A, Valero V, Symmans WF, Litton J, Triipathy D, Moulder S, Huo L. Predictive role of baseline stromal tumor-infiltrating lymphocytes and Ki-67 for pathologic complete response in an early-stage triple-negative breast cancer prospective trial. Cancers (Basel) 15(13):3275, 2023. e-Pub 2023. PMID: 37444385.
- Arribas EM, Kelil T, Santiago L, Ali A, Chadalavada SC, Chepelev L, Ghodadra A, Ionita CN, Lee J, Ravi P, Ryan JR, Sheikh AM, Rybicki FJ, Ballard DH, Voting Group RSIPBC. Radiological Society of North America (RSNA) 3D Printing Special Interest Group (SIG) clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: breast conditions. 3D Print Med 9(1):8, 2023. e-Pub 2023. PMID: 36952139.
- Echeverria GV, Cai S, Tu Y, Shao J, Powell E, Redwood AB, Jiang Y, McCoy A, Al R, Lau R, Trevarton AJ, FU C, Gould R, Ravenberg EE, Huo L, Candelaria R, Santiago L, Adrada BE, Lane DL, Rauch GM, Yang WT, White JB, Chang JT, Moulder S, Symmans WF, Hilsenbeck SG, Piwnica-Worms, H. Predictors of success in establishing orthotopic patient-derived xenograft models of triple negative breast cancer. NPJ Breast Cancer 9(1):2, 2023. e-Pub 2023. PMID: 36627285.
- Musall BC, Adrada BE, Candelaria RP, Mohamed RMM, Abdelhafez AH, Son JB, Sun J, Santiago L, Whitman GJ, Moseley TW, Scoggins ME, Mahmoud HS, White JB, Hwang KP, Elshafeey NA, Boge M, Zhang S, Litton JK, Valero V, Tripathy D, Thompson AM, Yam C, Wei P, Moulder SL, Pagel MD, Yang WT, Ma J, Rauch GM. Quantitative apparent diffusion coefficients from peritumoral regions as early predictors of response to neoadjuvant systemic therapy in triple-negative breast cancer. J Magn Reson Imaging 56(6):1901-1909, 2022. e-Pub 2022. PMID: 35499264.
- Huang ML, Hess K, Ma J, Santiago L, Scoggins ME, Arribas E, Adrada BE, Le-Petross HT, Leung JWT, Yang W, Geiser W, Candelaria RP. Prospective comparison of synthesized mammography with DBT and full-field digital mammography with DBT uncovers recall disagreements that may impact cancer detection. Acad Radiol 29(7):1039-1045, 2022. e-Pub 2022. PMID: 34538550.
- Abuhadra N, Sun R, Litton JK, Rauch GM, Yam C, Chang JT, Seth S, Bassett R, Lim B, Thompson AM, Mittendorf E, Adrada BE, Damodaran S, White J, Ravenberg E, Candelaria R, Arun B, Ueno NT, Santiago L, Saleem S, Abouharb S, Murthy RK, Ibrahim N, Sahin AA, Valero V, Symmans WF, Tripathy D, Moulder S, Huo L. Prognostic impact of high baseline stromal tumor-infiltrating lymphocytes in the absence of pathologic complete response in early-stage triple-negative breast cancer. Cancers (Basel) 14(5):1323, 2022. e-Pub 2022. PMID: 35267631.
- Candelaria RP, Spak DA, Rauch GM, Huo L, Bassett RL, Santiago L, Scoggins ME, Guirguis MS, Patel MM, Whitman GJ, Moulder SL, Thompson AM, Ravenberg EE, White JB, Abuhadra NK, Valero V, Litton J, Adrada BE, Yang WT. BI-RADS ultrasound lexicon descriptors and stromal tumor-infiltrating lymphocytes in triple-negative breast cancer. Acad Radiol 29:S35-S41, 2022. e-Pub 2022. PMID: 34272161.
- Adrada BE, Candelaria R, Moulder S, Thompson A, Wei P, Whitman GJ, Valero V, Litton JK, Santiago L, Scoggins ME, Moseley TW, White JB, Ravenberg EE, Yang WT, Rauch GM. Early ultrasound evaluation identifies excellent responders to neoadjuvant systemic therapy among patients with triple-negative breast cancer. Cancer 127(16):2880-2887, 2021. e-Pub 2021. PMID: 33878210.
- Bragg A, Candelaria R, Adrada B, Huang M, Rauch G, Santiago L, Scoggins M, Whitman G. Imaging of noncalcified ductal carcinoma in situ. J Clin Imaging Sci 16(11):34, 2021. e-Pub 2021. PMID: 34221643.
- Santiago L, Volk RJ, Checka CM, Black D, Lee J, Colen JS, Akay C, Caudle A, Kuerer H, Arribas EM. Acceptability of 3D-printed breast models and their impact on the decisional conflict of breast cancer patients: A feasibility study. J Surg Oncol 123(5):1206-1214, 2021. e-Pub 2021. PMID: 33577715.
- Abdelhafez AH, Musall BC, Adrada BE, Hess KR, Son JB, Hwang KP, Candelaria RP, Santiago L, Whitman GJ, Le-Petross HT, Moseley TW, Arribas E, Lane DL, Scoggins ME, Leung JWT, Mahmoud HS, White JB, Ravenberg EE, Litton JK, Valero V, Wei P, Thompson AM, Moulder SL, Pagel MD, Ma J, Yang WT, Rauch GM. Tumor necrosis by pretreatment breast MRI: Association with neoadjuvant systemic therapy (NAST) response in triple-negative breast cancer (TNBC). Breast Cancer Res and Treat 185(1):1-12, 2021. e-Pub 2021. PMID: 32920733.
- Yalniz C, Meis J, Wang W, Huo L, Candelaria RP, Adrada B, Lane D, Santiago L, Huang M. Proliferative fasciitis mimicking sarcoma in the breast. Breast J 26(10):2072-2074, 2020. e-Pub 2020. PMID: 32854140.
- Candelaria RP, Adrada B, Hess K, Santiago L, Lane D, Thompson A, Moulder S, Huang M, Arribas E, Rauch G, Leung JT, Symmans WF, Valero V, Ravenberg E, White JB, Yang WT. Axillary ultrasound during neoadjuvant systemic therapy in triple-negative breast cancer patients. European J of Radiol 130, 2020. e-Pub 2020. PMID: 32777736.
- DeFazio MV, Arribas EM, Ahmad FI, Le-Petross HT, Liu J, Chu CK, Santiago L, Clemens MW. Application of three-dimensional printed vascular modeling as a perioperative guide to perforator mapping and pedicle dissection during abdominal flap harvest for breast reconstruction. J Reconstr Microsurg 36(5):325-338, 2020. e-Pub 2020. PMID: 32000277.
- Ballard DH, Wake N, Witowski J, Rybicki Fj, Sheikh, RSNA Special Interest Group for 3D Printing, Hepatobiliary, Gastrointestinal Conditions Voting Group. Radiological Society of North America (RSNA) 3 D Printing Special Interest Group (SIG) clinical situations forwhich 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: abdominal, hepatobiliary, and gastrointestinal conditions. 3D Printing Med 6(1):13, 2020. e-Pub 2020. PMID: 32514795.
- Santiago L, Adrada B, Caudle AS, Clemens MW, Black DM, Arribas E. The role of three-dimensional printing in the surgical management of breast cancer. J Surg Oncol 120(6):897-902, 2019. e-Pub 2019. PMID: 31441070.
- Candelaria RP, Adrada BE, Wei W, Thompson AM, Santiago L, Lane DL, Huang ML, Arribas EM, Rauch GM, Symmans WF, Gilcrease MZ, Huo L, Lim B, Ueno NT, Moulder SL, Yang WT. Imaging features of triple-negative breast cancers according to androgen receptor status. Eur J Radiol 114:167-174, 2019. e-Pub 2019. PMID: 31005169.
- Tadros AB, Smith BD, Shen Y, Lin H, Krishnamurthy S, Lucci A, Barcenas CH, Hwang RF, Rauch G, Santiago L, Strom EA, DeSnyder SM, Yang WT, Black DM, Albarracin CT, Chavez-MacGregor M, Hunt KK, Kuerer HM. Ductal carcinoma in situ and margins <2mm: Contemporary outcomes with breast conservation. Ann Surg 269(1):150-157, 2019. e-Pub 2019. PMID: 28742682.
- Chepelev L, Wake N, Ryan J, Althobaity W, Gupta A, Arribas E, Santiago L, Ballard DH, Wang KC, Weadock W, Ionita CN, Mitsouras D, Morris J, Matsumoto J, Christensen A, Liacouras P, Rybicki FJ, Sheikh A, forD Printing RSIG. Radiological Society of North America (RSNA) 3D Printing Special Interest Group (SIG): Guidelines for medical 3D printing and appropriateness for clinical scenarios. 3D Print Med 4(1):11, 2018. e-Pub 2018. PMID: 30649688.
- Santiago L, Whitman G, Wang C, Dogan BE. Clinical and pathologic features of clinically occult synchronous bilateral breast cancers. Curr Probl Diagn Radiol 47(5):305-310, 2018. e-Pub 2018. PMID: 28935459.
- Rauch GM, Kuerer HM, Adrada B, Santiago L, Moseley T, Candelaria RP, Arribas E, Sun J, Leung JWT, Krishnamurthy S, Yang WT. Biopsy feasibility trial for breast cancer pathologic complete response detection after neoadjuvant chemotherapy: Imaging assessment and correlation endpoints. Ann Surg Oncol 25(7):1953-1960, 2018. e-Pub 2018. PMID: 29667115.
- Wang C, Wei W, Santiago L, Whitman G, Dogan B. Can imaging kinetic parameters of dynamic contrast-enhanced magnetic resonance imaging be valuable in predicting clinicopathological prognostic factors of invasive breast cancer?. Acta Radiol 59(7):813-821, 2018. e-Pub 2018. PMID: 29105486.
- Kuerer HM, Rauch GM, Krishnamurthy S, Adrada BE, Caudle AS, DeSnyder SM, Black DM, Santiago L, Hobbs BP, Lucci A, Gilcrease M, Hwang RF, Candelaria RP, Chavez-MacGregor M, Smith BD, Arribas E, Moseley T, Teshome M, Miggins MV, Valero V, Hunt KK, Yang WT. A clinical feasibility trial for identification of exceptional responders in whom breast cancer surgery can be eliminated following neoadjuvant systemic therapy. Ann Surg 267(5):946-951, 2018. e-Pub 2018. PMID: 28549010.
- Candelaria RP, Hansakul P, Thompson AM, Le-Petross H, Valero V, Bassett R, Huang ML, Santiago L, Adrada BE. Analysis of stereotactic biopsies performed on suspicious calcifications identified within 24 months after completion of breast conserving surgery and radiation therapy for early breast cancer: Can biopsy be obviated?. Am J Surg 215(4):693-698, 2018. e-Pub 2018. PMID: 28712671.
- Candelaria RP, Krishnamurthy S, Huang ML, Santiago L, Adrada BE. Imaging and pathological findings in a case of invasive squamous cell carcinoma of the breast. Breast J 24(2):203-204, 2018. e-Pub 2018. PMID: 28727282.
- Natesan R, Santiago L, Kalambo M, Martaindale S, Legha R, Weaver O, Batsell R, Wei W, Leung JWT, Yang WT. The impact of patient demographics on the selection of breast imaging centers. AJR Am J Roentgenol 209(3):W184-W193, 2017. e-Pub 2017. PMID: 28657849.
- Spak DA, Plaxco JS, Santiago L, Dryden MJ, Dogan BE. BI-RADS® fifth edition: A summary of changes. Diagn Interv Imaging 98(3):179-190, 2017. e-Pub 2017. PMID: 28131457.
- Shin K, Caudle AS, Kuerer HM, Santiago L, Candelaria RP, Dogan B, Leung J, Krishnamurthy S, Yang W. Radiologic mapping for targeted axillary dissection: Needle biopsy to excision. AJR Am J Roentgenol 207(6):1372-1379, 2016. e-Pub 2016. PMID: 27726422.
- Caudle AS, Yang WT, Krishnamurthy S, Mittendorf EA, Black DM, Gilcrease MZ, Bedrosian I, Hobbs BP, DeSnyder SM, Hwang RF, Adrada BE, Shaitelman SF, Chavez-MacGregor M, Smith BD, Candelaria RP, Babiera GV, Dogan BE, Santiago L, Hunt KK, Kuerer HM. Improved axillary evaluation following neoadjuvant therapy for patients with node-positive breast cancer using selective evaluation of clipped nodes: Implementation of targeted axillary dissection. J Clin Oncol 34(10):1072-8, 2016. e-Pub 2016. PMID: 26811528.
- Malowany JI, Kundu U, Santiago L, Krishnamurthy S. Fine-needle aspiration detects primary neuroendocrine carcinoma of the breast in a patient with breast implants. Cytojournal 12:1, 2015. e-Pub 2015. PMID: 25685170.
- Leong DL, Rainford L, Haygood TM, Whitman GJ, Geiser WR, Adrada BE, Santiago L, Brennan PC. Trend of contrast detection threshold with and without localization. J Digit Imaging 26(6):1099-106, 2013. e-Pub 2013. PMID: 23503988.
- Pan J, Dogan BE, Carkaci S, Santiago L, Arribas E, Cantor SB, Wei W, Stafford J, Whitman GJ. Comparing performance of the CADstream and the DynaCAD breast MRI CAD systems: CADstream vs. DynaCAD in breast magnetic resonance imaging. J Digit Imaging 26(5):971-6, 2013. e-Pub 2013. PMID: 23589186.
- Scoggins M, Krishnamurthy S, Santiago L, Yang W. Lobular carcinoma in situ of the breast: Clinical, radiological, and pathological correlation. Acad Radiol 20(4):463-70, 2013. e-Pub 2013. PMID: 23498988.
- Smith TB, Gilcrease MZ, Santiago L, Hunt KK, Yang WT. Imaging features of primary breast sarcoma. AJR Am J Roentgenol 198(4):386-93, 2012. e-Pub 2012. PMID: 22451578.
- Haygood TM, Arribas E, Liu QM, Atkinson EN, Brennan PC, Santiago L, Carkaci S, Lane D, Stephens TW, LePetross H, Adrada B, Davis P, Whitman GJ. Detection of microcalcifications on digital screening mammograms using varying degrees of monitor zooming. AJR Am J Roentgenol 197(4):W761-8, 2011. e-Pub 2011. PMID: 21940549.
- Carkaci S, Santiago L, Adrada BE, Whitman GJ. Screening for breast cancer with sonography. Semin Roentgenol 46(4):285-91, 2011. e-Pub 2011. PMID: 22035671.
- Shkumat NA, Springer A, Walker CM, Rohren EM, Yang WT, Adrada BE, Arribas E, Carkaci S, Chuang HH, Santiago L, Mawlawi OR. Investigating the limit of detectability of a positron emission mammography device: A phantom study. Med Phys 38(9):5176-85, 2011. e-Pub 2011. PMID: 21978062.
- Adejolu M, Wu Y, Santiago L, Yang WT. Adenomyoepithelial tumors of the breast: Imaging findings with histopathologic correlation. AJR Am J Roentgenol 197(1):184-190, 2011. e-Pub 2011. PMID: 21700984.
- Haygood TM, Arribas E, Brennan PC, Atkinson EN, Herndon M, Dieber J, Geiser W, Santiago L, Mills CM, Davis P, Adrada B, Carkaci S, Stephens TW, Whitman GJ. Conspicuity of microcalcifications on digital screening mammograms using varying degrees of monitor zooming. Acad Radiol 16(12):1509-17, 2009. e-Pub 2009. PMID: 19896068.
Review Articles
- Huang, ML, Lane, DL, Chang Sen, LQ, Candelaria, RP, Santiago, L. Postcryoablation Breast Imaging Algorithms, Findings, and Standardized Reporting. Journal of Breast Imaging 8(1):96-108, 2026. e-Pub 2026. PMID: 41558639.
- Guirguis MS, Adrada B, Santiago L, Candelaria R, Arribas E. Mimickers of breast malignancy: Imaging findings, pathologic concordance and clinical management. Insights Imaging 12(1):53, 2021. e-Pub 2021. PMID: 33877461.
- Santiago L, Candelaria RP, Huang ML. MRI imaging-guided breast interventions: Indications, key principles, and imaging-pathology correlation. Magn Reson Imaging Clin N Am 26(2):235-246, 2018. e-Pub 2018. PMID: 29622128.
- Santiago L, Adrada BE, Huang ML, Wei W, Candelaria RP. Breast cancer neoplastic seeding in the setting of image-guided needle biopsies of the breast. Breast Cancer Res Treat 166(1):29-39, 2017. e-Pub 2017. PMID: 28730339.
- Kuerer HM, Smith BD, Chavez-MacGregor M, Albarracin C, Barcenas CH, Santiago L, Edgerton ME, Rauch GM, Giordano SH, Sahin A, Krishnamurthy S, Woodward W, Tripathy D, Yang WT, Hunt KK. MD Anderson Cancer Center multidisciplinary practice guidelines and outcomes: Ductal carcinoma in situ margins and breast conservation. J Cancer 8(14):2653-2662, 2017. e-Pub 2017. PMID: 28928852.
- Adejolu M, Huo L, Rohren E, Santiago L, Yang WT. False-positive lesions mimicking breast cancer on FDG PET and PET/CT. AJR Am J Roentgenol 198(3):W304-14, 2012. e-Pub 2012. PMID: 22358030.
- Geiser WR, Haygood TM, Santiago L, Stephens T, Thames D, Whitman GJ. Challenges in mammography: Part 1, artifacts in digital mammography. AJR Am J Roentgenol 197(6):W1023-30, 2011. e-Pub 2011. PMID: 22109316.
Professional Educational Materials
- Arribas EM, Santiago L, Leung J. Three-dimensional printing in medicine, radiology and breast cancer, 2018.
- Santiago L. Nuclear medicine procedure booklet author for Spanish speaking patients at Lyndon B. Johnson Hospital, 2005.
Abstracts
- Rao SH, Tappa KK, Harris JM, Bird JE, Arribas E, Santiago L. A retrospective time and value analysis of orthopedic oncology cases using 3D Printing. Celebrate Solutions event re: 3D printing, 2025. e-Pub 2025.
- Patel MM, Dawson D, Adrada BE, Lane D, Santiago L. Troubleshooting on combined 2D/3D stereotactic/tomosynthesis breast biopsy units. Association of University Radiologist 66th Annual Meeting Program, 2018. e-Pub 2018.
Book Chapters
- Santiago L, Yang WT. Pectoralis muscle and chest wall. In: Diagnostic Imaging Breast. Second. Amirsys Publishing, Inc, 1(26-31), 2014.
- Santiago L. Stereotactic biopsy, upright. In: Diagnostic Imaging Breast. Second. Amirsys, Inc, 10 (20-27), 2014.
- Santiago L, Yang WT. Benign breast diseases in the elderly. In: Geriatric Imaging. Springer, 925-955, 2013.
- Carkaci S, Santiago L. Screening breast ultrasound. In: Advanced therapy of breast disease. Third. People's Medical Publishing House, 187-194, 2012.
Patient Reviews
CV information above last modified July 22, 2026