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Marc Delclos, MD

Present Title & Affiliation

Primary Appointment

Professor, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, The Woodlands, TX

Office Address

The University of Texas MD Anderson Cancer Center
17198 St. Luke's Way, Ste. 130
Unit Number: Unit 2030
The Woodlands, TX 77384

Education & Training

Degree-Granting Education

1992 Baylor College of Medicine, Houston, TX, MD, Medicine
1987 University of Houston, Houston, TX, BS, Science

Postgraduate Training

7/1993-6/1997 Clinical Residency, Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Dr. Patricia Eifel
7/1992-6/1993 Clinical Internship, Radiation Oncology, Baylor College of Medicine, Houston, TX, Dr. Tom Vargo

Board Certifications

4/2007 American Board of Radiology

Selected Publications

Peer-Reviewed Original Research Articles

1. Kelly P, Das P, Pinnix CC, Beddar S, Briere T, Pham M, Krishnan S, Delclos ME, Crane CH. Duodenal Toxicity After Fractionated Chemoradiation for Unresectable Pancreatic Cancer. Int J Radiat Oncol Biol Phys 85(3):e143-149, 3/2013. e-Pub 11/2012. PMID: 23200173.
2. Briere TM, Crane CH, Beddar S, Bhosale P, Mok H, Delclos ME, Krishnan S, Das P. Reproducibility and genital sparing with a vaginal dilator used for female anal cancer patients. Radiother Oncol 104(2):161-166, 8/2012. e-Pub 7/2012. PMID: 22841019.
3. Chakravarty T, Crane CH, Ajani JA, Mansfield PF, Briere TM, Beddar AS, Mok H, Reed VK, Krishnan S, Delclos ME, Das P. Intensity-Modulated Radiation Therapy with Concurrent Chemotherapy as Preoperative Treatment for Localized Gastric Adenocarcinoma. Int J Radiat Oncol Biol Phys 83(2):581-586, 6/2012. e-Pub 12/2011. PMID: 22137021.
4. Suzuki A, Xiao L, Taketa T, Blum MA, Matamoros A, Chien PL, Mansfield PF, Fournier KF, Weston B, Lee JH, Bhutani MS, Estrella JS, Delclos ME, Krishnan S, Das P, Ajani JA. Localized Gastric Cancer Treated with Chemoradation without Surgery: UTMD Anderson Cancer Center Experience. Oncology 82(6). e-Pub 6/2012. PMID: 22677933.
5. Kelly P, Das P, Varadhachary GR, Fontanilla HP, Krishnan S, Delclos ME, Jhingran A, Eifel PJ, Crane CH. Role of Definitive Radiation Therapy in Carcinoma of Unknown Primary in the Abdomen and Pelvis. Int J Radiat Oncol Biol Phys 82(5):2012-2017, 4/1/2012. e-Pub 6/2/2011. PMID: 21640510.
6. Skinner HD, Sharp HJ, Kaseb AO, Javle MM, Vauthey JN, Abdalla EK, Delclos ME, Das P, Crane CH, Krishnan S. Radiation treatment outcomes for unresectable hepatocellular carcinoma. Acta Oncol 50(8):1191-1198, 11/2011. e-Pub 7/2011. PMID: 21793641.
7. Dabaja BS, Rebueno NC, Mazloom A, Thorne S, Perrin KJ, Tolani N, Das P, Delclos ME, Iyengar P, Reed VK, Horace P, Salehpour MR. Radiation for Hodgkin's Lymphoma in Young Female Patients: A New Technique to Avoid the Breasts and Decrease the Dose to the Heart. Int J Radiat Oncol Biol Phys 79(2):503-507, 2/2011. e-Pub 4/2010. PMID: 20418023.
8. Mok H, Crane CH, Palmer MB, Briere TM, Beddar S, Delclos ME, Krishnan S, Das P. Intensity modulated radiation therapy (IMRT): differences in target volumes and improvement in clinically relevant doses to small bowel in rectal carcinoma. Radiat Oncol 6:63, 2011. e-Pub 6/2011. PMCID: PMC3121606.
9. Das P, Delclos ME, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Eng C, Bedi M, Krishnan S, Crane CH. Hyperfractionated accelerated radiotherapy for rectal cancer in patients with prior pelvic irradiation. Int J Radiat Oncol Biol Phys 77(1):60-65, 5/2010. e-Pub 8/2009. PMID: 19695792.
10. Das P, Cantor SB, Parker CL, Zampieri JB, Baschnagel A, Eng C, Delclos ME, Krishnan S, Janjan NA, Crane CH. Long-term quality of life after radiotherapy for the treatment of anal cancer. Cancer 116(4):822-829, 2/2010. PMID: 20041481.
11. Hodges JC, Das P, Eng C, Reish AG, Beddar AS, Delclos ME, Krishnan S, Crane CH. Intensity-Modulated Radiation Therapy for the Treatment of Squamous Cell Anal Cancer with Para-aortic Nodal Involvement. Int J Radiat Oncol Biol Phys 75(3):791-794, 11/2009. e-Pub 2/2009. PMID: 19231109.
12. Park HC, Janjan NA, Mendoza TR, Lin EH, Vadhan-Raj S, Hundal M, Zhang Y, Delclos ME, Crane CH, Das P, Wang XS, Cleeland CS, Krishnan S. Temporal Patterns of Fatigue Predict Pathologic Response in Patients Treated with Preoperative Chemoradiation Therapy for Rectal Cancer. Int J Radiat Oncol Biol Phys 75(3):775-781, 11/2009. e-Pub 2/2009. PMID: 19231100.
13. Callender GG, Das P, Rodriguez-Bigas MA, Skibber JM, Crane CH, Krishnan S, Delclos ME, Feig BW. Local Excision After Preoperative Chemoradiation Results in an Equivalent Outcome to Total Mesorectal Excision in Selected Patients with T3 Rectal Cancer. Ann Surg Oncol 17(2):441-447, 10/2009. e-Pub 10/2009. PMID: 19847569.
14. Herman MP, Kopetz S, Bhosale PR, Eng C, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Janjan NA, Delclos ME, Krishnan S, Crane CH. Sacral insufficiency fractures after preoperative chemoradiation for rectal cancer: Incidence, risk factors and clinical course. Int J Radiat Oncol Biol Phys 74(3). e-Pub 1/2009. PMID: 19147305.
15. Haque W, Crane CH, Krishnan S, Delclos ME, Javle M, Garrett CR, Wolff RA, Das P. Reirradiation to the abdomen for gastrointestinal malignancies. Radiat Oncol 4:55, 2009. PMCID: PMC2787526.
16. Reed VK, Krishnan S, Mansfield PF, Bhosale PR, Kim M, Das P, Janjan NA, Delclos ME, Lowy AM, Feig BW, Pisters PW, Ajani JA, Crane CH. Incidence, natural history, and patterns of locoregional recurrence in gastric cancer patients treated with preoperative chemoradiotherapy. Int J Radiat Oncol Biol Phys 71(3):741-747, 7/2008. e-Pub 12/2007. PMID: 18164837.
17. Yu TK, Bhosale PR, Crane CH, Iyer RB, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Eng C, Wolff RA, Janjan NA, Delclos ME, Krishnan S, Das P. Patterns of locoregional recurrence after surgery and radiotherapy or chemoradiation for rectal cancer. Int J Radiat Oncol Biol Phys 71(4):1175-1180, 7/2008. e-Pub 1/2008. PMID: 18207667.
18. Kim MM, Mansfield PF, Das P, Janjan NA, Badgwell BD, Phan AT, Delclos ME, Maru D, Ajani JA, Crane CH, Krishnan S. Chemoradiation therapy of potentially resectable gastric cancer: clinical outcomes among patients who do not undergo planned surgery. Int J Radiat Oncol Biol Phys 71(1):167-172, 5/2008.
19. Kim MM, Rana V, Janjan NA, Das P, Phan AT, Delclos ME, Mansfield PF, Ajani JA, Crane CH, Krishnan S. Clinical benefit of palliative radiation therapy in advanced gastric cancer. Acta Oncol 47(3):421-427, 2008. e-Pub 9/2007. PMID: 17899453.
20. Krishnan S, Rana V, Evans DB, Varadhachary G, Das P, Bhatia S, Delclos ME, Janjan NA, Wolff RA, Crane CH, Pisters PW. Role of Adjuvant Chemoradiation Therapy in Adenocarcinomas of the Ampulla of Vater. Int J Radiat Oncol Biol Phys 70(3):735-743, 2008.
21. Gao S, Delclos ME, Tomas LC, Crane CH, Beddar S. High dose rate remote afterloaders for intraoperative radiation therapy. AORN 86(5)(5):827-840, 11/2007. PMID: 18050890.
22. Krishnan S, Rana V, Janjan NA, Varadhachary GR, Abbruzzese JL, Das P, Delclos ME, Gould MS, Evans DB, Wolff RA, Crane CH. Induction chemotherapy selects patients with locally advanced, unresectable pancreatic cancer for optimal benefit from consolidative chemoradiation therapy. Cancer 110(1):47-55, 7/2007. e-Pub 1/2008. PMID: 17538975.
23. Das P, Bhatia S, Eng C, Ajani JA, Skibber JM, Rodriguez-Bigas MA, Chang GJ, Bhosale P, Delclos ME, Krishnan S, Janjan NA, Crane CH. Predictors and patterns of recurrence after definitive chemoradiation for anal cancer. Int J Radiat Oncol Biol Phys 68:794-800, 7/2007. PMID: 17379452.
24. Das P, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Hoff PM, Eng C, Wolff RA, Janjan NA, Delclos ME, Krishnan S, Levy LB, Ellis LM, Crane CH. Clinical and pathologic predictors of locoregional recurrence, distant metastasis, and overall survival in patients treated with chemoradiation and mesorectal excision for rectal cancer. Am J Clin Oncol 29(3):219-224, 2006. PMID: 16755173.
25. Das P, Wolff RA, Abbruzzese JL, Varadhachary GR, Evans DB, Vauthey JN, Baschnagel A, Delclos ME, Krishnan S, Janjan NA, Crane CH. Concurrent capecitabine and upper abdominal radiation therapy is well tolerated. Radiat Oncol 1:41, 2006. PMID: 17062148.
26. Krishnan S, Lin EH, Gunn GB, Chandra A, Beddar AS, Briere TM, Das P, Delclos ME, Janjan NA, Crane CH. Conformal radiotherapy of the dominant liver metastasis: a viable strategy for treatment of unresectable chemotherapy refractory colorectal cancer liver metastases. Am J Clin Oncol 29(6):562-567, 2006. PMID: 17148992.
27. Bedrosian I, Giacco G, Pederson L, Rodriguez-Bigas MA, Feig B, Hunt KK, Ellis L, Curley SA, Vauthey JN, Delclos M, Crane CH, Janjan N, Skibber JM. Outcome after curative resection for locally recurrent rectal cancer. Dis Colon Rectum 49(2):175-182, 2006.
28. Crane CH, Ellis LM, Abbruzzese JL, Amos C, Xiong HQ, Ho L, Evans DB, Tamm EP, Ng C, Pisters PW, Charnsangavej C, Delclos ME, O'Reilly M, Lee JE, Wolff RA. Phase I trial evaluating the safety of bevacizumab with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer. J Clin Oncol 24:1145-1151, 2006. PMID: 16505434.
29. Krishnan S, Janjan NA, Skibber JM, Rodriguez-Bigas MA, Wolff RA, Das P, Delclos ME, Chang GJ, Hoff PM, Eng C, Brown TD, Crane CH, Feig BW, Morris J, Vadhan-Raj S, Hamilton SR, Lin EH. Phase II study of capecitabine (Xeloda) and concomitant boost radiotherapy in patients with locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 66(3):762-771, 2006. PMID: 17011451.
30. Das P, Lin EH, Bhatia S, Skibber JM, Rodriguez-Bigas MA, Feig BW, Chang GJ, Hoff PM, Eng C, Wolff RA, Delclos ME, Krishnan S, Janjan NA, Crane CH. Preoperative chemoradiotherapy with capecitabine versus protracted infusion 5-fluorouracil for rectal cancer: a matched-pair analysis. Int J Radiat Oncol Biol Phys 66:1378-1383, 2006. PMID: 17056196.
31. Krishnan S, Rana V, Janjan NA, Abbruzzese JL, Gould MS, Das P, Delclos ME, Palla S, Guha S, Varadhachary G, Evans DB, Wolff RA, Crane CH. Prognostic factors in patients with unresectable locally advanced pancreatic adenocarcinoma treated with chemoradiation. Cancer 107(11):2589-2596, 2006. PMID: 17083124.
32. Lin EH, Curley SA, Crane CC [sic], Feig B, Skibber J, Delclos M, Vadhan SR, Morris J, Ayers GD, Ross A, Brown T, Rodriguez-Bigas MA, Janjan N. Retrospective study of capecitabine and celecoxib in metastic colorectal cancer: potential benefits and COX-2 as the common mediator in pain, toxicities and survival? Am J Clin Oncol 29(3):232-239, 2006.
33. Beddar AS, Krishnan S, Briere TM, Wang X, Delclos ME, Ballo MT, Das P, Gould S, Horton JL, Crane CH. The optimization of dose delivery for intraoperative high-dose-rate radiation therapy using curved HAM applicators. Radiother Oncol 78(2):207-212, 2006. PMID: 16376445.
34. Wong AA, Delclos ME, Wolff RA, Evans DB, Abbruzzese JL, Tamm EP, Xiong HQ, Ho L, Crane CH. Radiation dose considerations in the palliative treatment of locally advanced adenocarcinoma of the pancreas. Am J Clin Oncol 28(3):227-233, 2005. PMID: 15923793.
35. Bonnen M, Crane C, Vauthey JN, Skibber J, Delclos ME, Rodriguez-Bigas M, Hoff PM, Lin E, Eng C, Wong A, Janjan NA, Feig BW. Long-term results using local excision after preoperative chemoradiation among selected T3 rectal cancer patients. Int J Radiat Oncol Biol Phys 60(4):1098-1105, 2004. PMID: 15519780.
36. Bedrosian I, Rodriguez-Bigas MA, Feig B, Hunt KK, Ellis L, Curley SA, Vauthey JN, Delclos M, Crane C, Janjan N, Skibber JM. Predicting the node-negative mesorectum after preoperative chemoradiation for locally advanced rectal carcinoma. J Gastrointest Surg 8(1):56-62; discussion 62-63, 2004. PMID: 14746836.
37. Crane CH, Ellis LM, O'Reilly M, Ho L, Abbruzzese JL, Evans DB, Ng C, Charnsangavej C, Tamm EP, Xiong HQ, Delclos ME, Wolff RA. RhuMab VEGF (Bevacizumab) with concurrent radiotherapy and capecitabine in locally advanced pancreatic cancer: an active, well tolerated regimen. Int J Radiat Oncol Biol Phys 60:S149, 2004.
38. Papagikos M, Crane CH, Skibber J, Janjan NA, Feig B, Rodriguez-Bigas MA, Hung A, Wolff RA, Delclos M, Lin E, Cleary K. Chemoradiation for adenocarcinoma of the anus. Int J Radiat Oncol Biol Phys 55(3):669-778, 2003. PMID: 12573754.
39. Hung A, Crane C, Delclos M, Ballo M, Ajani J, Lin E, Feig B, Skibber J, Janjan N. Cisplatin-based combined modality therapy for anal carcinoma: a wider therapeutic index. Cancer 97(5):1195-1202, 2003. PMID: 12599225.
40. Crane CH, Skibber JM, Feig BW, Vauthey JN, Thames HD, Curley SA, Rodriguez-Bigas MA, Wolff RA, Ellis LM, Delclos ME, Lin EH, Janjan NA. Response to preoperative chemoradiation increases the use of sphincter-preserving surgery in patients with locally advanced low rectal carcinoma. Cancer 97(2):517-524, 2003. PMID: 12518377.
41. Crane CH, Skibber JM, Birnbaum EH, Feig BW, Singh AK, Delclos ME, Lin EH, Fleshman JW, Thames HD, Kodner IJ, Lockett MA, Picus J, Phan T, Chandra A, Janjan NA, Read TE, Myerson RJ. The addition of continuous infusion 5-FU to preoperative radiation therapy increases tumor response, leading to increased sphincter preservation in locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 57(1):84-89, 2003. PMID: 12909219.
42. Janjan N, Crane C, Delclos M, Ballo M. Brachytherapy for locally recurrent soft-tissue sarcoma. Am J Clin Oncol 25(1):9-15, 2002. PMID: 11823688.
43. Crane CH, Abbruzzese JL, Evans DB, Wolff RA, Ballo MT, Delclos M, Milas L, Mason K, Charnsangavej C, Pisters PW, Lee JE, Lenzi R, Vauthey JN, Wong AB, Phan T, Nguyen Q, Janjan NA. Is the therapeutic index better with gemcitabine-based chemoradiation than with 5-fluorouracil-based chemoradiation in locally advanced pancreatic cancer? Int J Radiat Oncol Biol Phys 52(5):1293-1302, 2002. PMID: 11955742.
44. Crane CH, Macdonald KO, Vauthey JN, Yehuda P, Brown T, Curley S, Wong A, Delclos M, Charnsangavej C, Janjan NA. Limitations of conventional doses of chemoradiation for unresectable biliary cancer. Int J Radiat Oncol Biol Phys 53(4):969-974, 2002. PMID: 12095564.
45. Kelly JF, Delclos ME, Morice RC, Huaringa A, Allen PK, Komaki R. High-dose-rate endobronchial brachytherapy effectively palliates symptoms due to airway tumors: the 10-year M. D. Anderson cancer center experience. Int J Radiat Oncol Biol Phys 48(3):697-702, 2000. PMID: 11020566.
46. Komaki R, Roth JA, Walsh GL, Putnam JB, Vaporciyan A, Lee JS, Fossella FV, Chasen M, Delclos ME, Cox JD. Outcome predictors for 143 patients with superior sulcus tumors treated by multidisciplinary approach at the University of Texas M. D. Anderson Cancer Center. Int J Radiat Oncol Biol Phys 48(2):347-354, 2000. PMID: 10974447.
47. Delclos ME, Komaki R, Morice RC, Allen PK, Davis M, Garden A. Endobronchial brachytherapy with high-dose-rate remote afterloading for recurrent endobronchial lesions. Radiology 201(1):279-282, 1996. PMID: 8816560.

Last updated: 4/4/2014