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      Michael A. Davies Image

      Michael A. Davies, M.D., Ph.D.

      Department of Melanoma Medical Oncology, Division of Cancer Medicine

      About Dr. Michael A. Davies

      Michael Davies, M.D., Ph.D., is an Professor and the Chairman of the Department of Melanoma Medical Oncology.  He has joint appointments in the Department of Systems Biology and the Department of Translational Molecular Pathology.  He is an expert in the management of patients with advanced melanoma, including treatment with immunotherapy, targeted therapy, and chemotherapy, as well as the development of integrated multidisciplinary care plans.  In addition to providing standard of care therapies, he has designed and led multiple clinical trials for patients with advanced melanoma. 

      Dr. Davies also leads a translational laboratory research program.  His research has identified clinical associations of oncogenic mutations and signaling pathways; novel strategies to overcome resistance to targeted and immune therapies; and new predictors and therapeutic approaches for central nervous system (CNS) metastases from melanoma.  Dr. Davies is an elected member of the American Society for Clinical Investigation, and he is the co-leader of the MD Anderson Melanoma Moon Shot Program. 

      Read More

      Present Title & Affiliation

      Primary Appointment

      Anne and John Mendelsohn Endowed Chair in Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX

      Professor, Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

      Chair, Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

      Professor (Joint appointment), Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

      Member, Heme/Onc Fellowship Program Executive Committee, Hematology/Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

      Dual/Joint/Adjunct Appointment

      Anne and John Mendelsohn Endowed Chair in Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX

      Professor, Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

      Professor, Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

      Chair, Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

      Education & Training

      Degree-Granting Education

      2001The University of Texas Health Science Center, Houston, Texas, US, Molecular Biology, MD, PhD
      1993The University of Texas at Austin, Austin, Texas, US, Liberal Arts, BA

      Postgraduate Training

      2004-2007Clinical Fellowship, Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
      2001-2004Clinical Residency, Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts

      Licenses & Certifications

      2024Interstate Medical Licensure Compact, Washington Medical Commission
      2023Tennessee Board of Medical Examiners
      2023Mississippi State Board Medical License
      2023Georgia Composite Medical Board License
      2023Louisiana State Board of Medical Examiners
      2023Oklahoma State Board of Medical Licensure
      2023Alabama Board of Medical Examiners
      2023Georgia Composite Medical Board
      2023Licensure
      2023Oklahoma Board of Medical Licensure and Supervision
      2023Louisiana State Board of Medical Examiners Physician & Surgeon Compact License
      2023Alabama Board of Medical Examiners
      2023Arizona Board of Medical Examiners
      2023Tennessee Medical License-Medicine and Surgery
      2023Washington State Department of Health Physician and Surgeon License-Interstate Medical Licensure Compact
      2021Arizona Board of Medical Examiners
      2021Florida Board of Medicine
      2007Medical Oncology
      2004Texas Medical Board Physician License
      2004American Board of Internal Medicine
      2002Massachusetts Medical License

      Experience & Service

      Faculty Academic Appointments

      Professor, Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2019 - 2025

      Professor (Joint appointment), Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2025

      Professor, Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2022

      Associate Professor, Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2019

      Deputy Chair, Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2019

      Director of Research Activities, Hematology/Oncology Fellowship Program, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2025

      Associate Professor, Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2013 - 2019

      Associate Professor, Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2019

      Co-Leader, Melanoma Moon Shot Program, Moon Shots Program, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2025

      Assistant Professor, Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2008 - 2013

      Assistant Professor, Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2007 - 2013

      Fellow, Division of Cancer Medicine Hematology/Oncology Fellowship Program, The University of Texas MD Anderson Cancer Center, Houston, TX, 2004 - 2007

      Resident, Internal Medicine, Massachusetts General Hospital, Boston, MA, 2002 - 2004

      Intern, Internal Medicine, Massachusetts General Hospital, Boston, MA, 2001 - 2002

      Graduate Research Assistant, Neuro-oncology and Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 1998 - 2001

      Graduate Research Assistant, Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 1997 - 1997

      Teaching Assistant, Neuro-anatomy, The University of Texas Medical School, Houston, TX, 1996

      Undergraduate Research Assistant, Allergan Pharmaceuticals, Irvine, CA, 1993 - 1993

      Undergraduate Research Assistant, Pharmacy, The University of Texas at Austin, Austin, TX, 1991 - 1994

      Administrative Appointments/Responsibilities

      Director of Melanoma and Skin Cancer SPORE Seminar Series, Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - Present

      Co-Chair, Clinical Research Committee, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2019

      Faculty Mentor, Medical Oncology Fellowship Program associated with T32 CA009666 - Research Training in Academic Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - Present

      Co-Leader, Melanoma Moon Shot Program, Moon Shots Program, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - Present

      MD/PhD Program Admissions Committee Member, The University of Texas Health Science Center, Houston, TX, 2008 - Present

      Course Director, Division of Cancer Medicine, Core Curriculum Course, The University of Texas MD Anderson Cancer Center, Houston, TX, 2005 - 2006

      Other Professional Positions

      Scientific Advisory Committee Member, Melanoma Research Foundation, 2024 - Present

      Internal Advisory Board Member, Specialized Programs of Research Excellence (SPOREs) in Human Cancers, 2024 - 2026

      Scientific Advisory Board Member, Andrew McDougall Brian Metastasis Clinic and Research Program, Virtual, 2023 - Present

      Co-Director, Department of Defense Melanoma Academy, Boston, MA, 2022 - Present

      Scientific Advisory Board Member, Iovance Biotherapeutics, Virtual, 2022

      Scientific Advisory Board Member, ABM Therapeutics, Inc, Virtual, 2021 - 2024

      Melanoma Publication Committee Advisor, Novartis Pharmaceuticals Corporation, Houston, 2021 - Present

      External Advisory Board Member, Bristol-Myers Squibb Company (BMS), Virtual, 2020 - Present

      External Advisory Board Member, University of Pennsylvania SPORE, Pennsylvania, 2019 - Present

      Melanoma Senior Editor, Clinical Cancer Research, Chicago, IL, 2017 - 2019

      Member, The TCGA Melanoma Analysis Working Group, Houston, TX, 2012 - Present

      Member, MRF Breakthrough Consortium (MRFBC) Signal Transduction Subcommittee, Washington, DC, 2011 - 2024

      Member, MRF Breakthrough consortium (MRFBC) Translational Subcommittee, Houston, 2010 - Present

      Member, International Melanoma Working Group, Naples, 2010 - Present

      Graduate School of Biomedical Sciences Faculty Member, The University of Texas Health Science Center at Houston, Houston, TX, 2008 - Present

      Extramural Institutional Committee Activities

      Internal Advisor for program proceedings and operations, Division of Cancer Medicine Hematology T32 Fellowship Advisory Board, The University of Texas MD Anderson Cancer Center, 2024 - 2030

      Chair Representative, Strategic Position Management Committee (SPMC) Non-Faculty Research & Education Task Force, The University of Texas MD Anderson Cancer Center, 2023 - Present

      Planning Committee Member, DoCM Grand Rounds, The University of Texas MD Anderson Cancer Center, 2023 - Present

      Leader, Faculty Evaluations Subgroup, MDACC Community of Chairs, The University of Texas MD Anderson Cancer Center, 2022 - Present

      Member, The University of Texas MD Anderson Cancer Center Community of Chairs: Strategic Plan Breakthrough Committee, The University of Texas MD Anderson Cancer Center, 2021 - Present

      Research Mentor, NIH R25 UPWARDS Research Training Program, The University of Texas MD Anderson Cancer Center, 2021 - 2023

      Research Mentor, CPRIT CURE Summer Undergraduate Program, The University of Texas MD Anderson Cancer Center, 2021 - 2021

      Research Mentor, NIH Faculty Institutional Recruitment for Sustainable Transformation (FIRST) Program, The University of Texas MD Anderson Cancer Center, 2021 - Present

      Committee Member, Wall of Science, The University of Texas MD Anderson Cancer Center, 2019 - 2023

      Member, Community of Chairs, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, 2019 - Present

      Member, Advanced Scholar Program Executive Committee, The University of Texas MD Anderson Cancer Center, 2013 - Present

      Member, The University of Texas MD Anderson Cancer Center Molecular Tumor Board, The University of Texas MD Anderson Cancer Center, 2012 - 2013

      Member, The University of Texas MD Anderson Cancer Center Clinical Research Committee, The University of Texas MD Anderson Cancer Center, 2011 - 2015

      Member, Molecular Testing Task Force, The University of Texas MD Anderson Cancer Center, 2010 - 2013

      Member, The University of Texas MD Anderson Cancer Center Pharmacy & Therapeutics Committee, The University of Texas MD Anderson Cancer Center, 2009 - 2014

      Member, The University of Texas MD Anderson Cancer Center IRG Grant Review Study Section/Committee, The University of Texas MD Anderson Cancer Center, 2009 - 2012

      Member, The University of Texas MD Anderson Cancer Center South Campus Transportation Committee, The University of Texas MD Anderson Cancer Center, 2009 - 2015

      Editorial Activities

      Senior Editor for Melanoma, Clinical Cancer Research, 2017 - 2019

      Editorial Board Member, Clinical cancer research : an official journal of the American Association for Cancer Research, 2015 - Present

      Board Member, Precision Oncology, 2013

      Guest Editor, The Cancer Journal, 2012

      Board Member, Biochemical Pharmacology, 2010

      Honors & Awards

      2025 - PresentTop 10% in the nation for delivering compassionate, high-quality care throughout Fiscal Year 2025, Clinician and Group Consumer Assessment of Healthcare Providers and Systems (CGCAHPS)
      2022Ranked Top 10% nationally for exceptional communication with patients and families for the Fiscal Year, Clinician and Group Consumer Assessment of Healthcare Providers and Systems
      2019Ranked top 1% nationally for exceptional communication with patients and families for the Fiscal Year, Clinician and Group Consumer Assessment of Healthcare Providers and Systems
      2019Mentor of the Year Award, MD Anderson Division of Cancer Medicine Hematology/Oncology Fellowship Program
      2016Member, American Society for Clinical Investigation
      2015Gerald P. Bodey Award for Excellence in Education, MDACC Division of Cancer Medicine
      2015Leadership in Education, Division of Cancer Medicine, MD Anderson Cancer Center, MD Anderson Cancer Center
      2010 - 2011Goodfellow Scholar, MD Anderson Cancer Center
      2010ASCO Career Development Award, American Society of Clinical Oncology
      2010Wilson S. Stone Memorial Award, MD Anderson Cancer Center
      2009Team Science Award, MD Anderson Cancer Center
      2007Outstanding Achievement in Basic Science Research, Medical Oncology Fellowship Program, MD Anderson Cancer Center
      2006Carol Codgell Courtney Fellowship, MD Anderson Cancer Center
      2005Young Investigator Award, American Society of Clinical Oncology
      2000Amgen Award in Basic Science Research, MD Anderson Cancer Center
      2000Alpha Omega Alpha, Medical Honor Society
      1999President's Research Scholarship, Graduate School of Biomedical Sciences
      1999Cancer Answers/Sylvan Rodriguez Scholarship, Graduate School of Biomedical Sciences
      1993Phi Beta Kappa, Undergraduate Honor Society, Phi Beta Kappa

      Professional Memberships

      Consortium for Intracranial Metastasis Academic Research (CIMARa)

      2021 - Present

      SWOG

      2015 - Present

      American Society for Clinical Investigation (ASCI)

      2015 - Present

      Society for Melanoma Research

      2010 - Present

      American Association for Cancer Research

      2008 - Present

      Harris County Medical Association

      2007 - Present

      American Society of Clinical Oncology

      2004 - Present

      American Medical Association

      2000 - 2003

      Selected Presentations & Talks

      Local Presentations

      1. 2026. Development of New Targeted Therapy Strategies for Melanoma CNS Metastases. Invited. Brain Metastasis Lab Meeting. Houston, Texas, US.
      2. 2025. What is the Role of Targeted Therapy for Stage IV Melanoma. Invited. The Art and Science of Managing Melanoma & Non-Melanoma Skin Cancers. Houston, Texas, US.
      3. 2025. Adjuvant and Neo-Adjuvant Therapy: Adjuvant Therapy for Regional Disease-Options and Controversies. Invited. The Art and Science of Managing Melanoma & Non-Melanoma Skin Cancers. Houston, Texas, US.
      4. 2025. Adjuvant Therapy for Clinically Localized Melanoma-Options and Controversies. Invited. The Art and Science of Managing Melanoma & Non-Melanoma Skin Cancers. Houston, TX, US.
      5. 2024. Melanoma CNS Metastases-Progress Made and Lessons Learned. Invited. Inflammatory Breast Cancer (IBC) Research Seminar. Houston, Texas, US.
      6. 2024. Andrew M. McDougall Brain Metastasis Clinic. Invited. Midland Making Cancer History Cancer Seminar. Midland, Texas, US.
      7. 2023. BRAF, A Therapeutic Opportunity Across Cancers. Conference. MD Anderson Cancer Physician Network. Virtual, TX, US.
      8. 2023. Introduction & History. Conference. DoCM Grand Rounds: Melanoma Moon Shot Program, Moon Shots Operations. Virtual, TX, US.
      9. 2023. Melanoma Moon Shot: Qtr 2 - Project 2. Conference. Melanoma Moon Shot: Qtr 2 - Project 2. Virtual, US.
      10. 2023. Role of Aberrant Metabolic Pathways in Brain Metastasis. Conference. Role of Aberrant Metabolic Pathways in Brain Metastasis. Houston, TX, US.
      11. 2023. State of the Department: A Department of Melanoma Update. Conference. State of the Department: A Department of Melanoma Update. Virtual, US.
      12. 2022. Medical Oncology: Dual or Triplet?. Conference. Medical Oncology: Dual or Triplet?. Virtual, US.
      13. 2022. BRAFi + MEKi Targeted Therapy for Metastatic Melanoma, 2022. Conference. BRAFi + MEKi Targeted Therapy for Metastatic Melanoma, 2022. Virtual, US.
      14. 2022. Advancing the Understanding, Treatments and Outcomes of Melanoma Brain Metastases. Conference. Advancing the Understanding, Treatments and Outcomes of Melanoma Brain Metastases. Virtual, US.
      15. 2021. What's New: Medical Oncology. Conference. What's New: Medical Oncology. Virtual, US.
      16. 2021. Oxidative Phosphorylation in Metastasis and Therapeutic Resistance in Melanoma. Conference. Oxidative Phosphorylation in Metastasis and Therapeutic Resistance in Melanoma. Virtual, TX, US.
      17. 2021. T32 Research Training in Academic Medical Oncology Overview. Conference. T32 Research Training in Academic Medical Oncology Overview. Virtual, TX, US.
      18. 2021. T32 Research Training in Academic Medical Oncology Overview. Conference. T32 Research Training in Academic Medical Oncology Overview. Virtual, TX, US.
      19. 2021. MD/PhD Training Programs and the Physician-Scientist Career Pathway. Conference. MD/PhD Training Programs and the Physician-Scientist Career Pathway. Virtual, TX, US.
      20. 2021. Melanoma Moon Shot. Conference. Melanoma Moon Shot. Virtual, US.
      21. 2021. Big Survey. Conference. Big Survey. Virtual, US.
      22. 2021. Recent Advances & Novel Approaches for Metastatic Melanoma. Conference. Recent Advances & Novel Approaches for Metastatic Melanoma. Virtual, US.
      23. 2020. Breakthroughs in the Understanding and Treatment of CNS Metastases from Melanoma. Conference. Breakthroughs in the Understanding and Treatment of CNS Metastases from Melanoma. Virtual, US.
      24. 2020. Molecular Biology and Therapy of Cancer. Conference. Molecular Biology and Therapy of Cancer. Virtual, US.
      25. 2020. Immunotherapy for Stage IV Melanoma: Standards, Questions and Investigations. Conference. Immunotherapy for Stage IV Melanoma: Standards, Questions and Investigations. Virtual, US.
      26. 2020. Targeted Therapy for Metastatic Melanoma, 2020. Conference. Targeted Therapy for Metastatic Melanoma, 2020. Virtual, US.
      27. 2020. Melanoma MD Anderson Multidisciplinary Care Discussion Panel: Medical Oncology. Conference. Melanoma MD Anderson Multidisciplinary Care Discussion Panel: Medical Oncology. Virtual, US.
      28. 2020. T32 Research Training in Academic Medical Oncology Overview. Conference. T32 Research Training in Academic Medical Oncology Overview. Virtual, TX, US.
      29. 2020. Melanoma CNS Metastases - Clinical and Translational Research Advances and Opportunities. Conference. Melanoma CNS Metastases - Clinical and Translational Research Advances and Opportunities. Houston, TX, US.
      30. 2019. The Role of Metabolism in Metastasis and Therapeutic Resistance in Melanoma. Conference. The Role of Metabolism in Metastasis and Therapeutic Resistance in Melanoma. Houston, TX, US.
      31. 2019. Identifying and Overcoming Resistance to Melanoma Systemic Therapy. Conference. Identifying and Overcoming Resistance to Melanoma Systemic Therapy. Houston, TX, US.
      32. 2019. What's New in Targeted Therapy for Melanoma. Conference. What's New in Targeted Therapy for Melanoma. Houston, TX, US.
      33. 2019. Breakthroughs in the Understanding & Treatment of Brain Metastases. Conference. Breakthroughs in the Understanding & Treatment of Brain Metastases. Houston, TX, US.
      34. 2018. New Approaches to Immunotherapy. Conference. New Approaches to Immunotherapy. Houston, TX, US.
      35. 2018. CNS Metastases: The Role of Systemic Therapy. Conference. MD Anderson Cancer Center. Houston, TX, US.
      36. 2017. Targeted Therapy for BRAF-Mutant Melanoma, 2017. Conference. Targeted Therapy for BRAF-Mutant Melanoma, 2017. Houston, TX, US.
      37. 2017. The Melanoma Moon Shot: New Paradigms, Progress and Opportunities. Conference. The Melanoma Moon Shot: New Paradigms, Progress and Opportunities. Houston, TX, US.
      38. 2016. Melanoma-How Research is Transforming Patient Care and Outcomes. Conference. Melanoma-How Research is Transforming Patient Care and Outcomes. Houston, TX, US.
      39. 2016. Melanoma: New Insights into Oncogenes, Immunology, Metastasis, and Resistance. Conference. Melanoma: New Insights into Oncogenes, Immunology, Metastasis, and Resistance. Houston, TX, US.
      40. 2016. Immunotherapy Clinical Studies Across Tumor Types: Malignant Melanoma. Conference. Immunotherapy Clinical Studies Across Tumor Types: Malignant Melanoma. Houston, TX, US.
      41. 2015. Unraveling and Translating the Molecular Basis of Melanoma. Conference. Unraveling and Translating the Molecular Basis of Melanoma. Houston, TX, US.
      42. 2015. Optimizing Targeted Therapy for Melanoma. Conference. Optimizing Targeted Therapy for Melanoma. Houston, TX, US.
      43. 2015. Recent Advances in the treatment of Metastatic Melanoma. Conference. Recent Advances in the treatment of Option for Metastatic Melanoma. Houston, TX, US.
      44. 2014. Melanoma Brain Metastases: Molecular Characterization and Treatment. Conference. Melanoma Brain Metastases: Molecular Characterization and Treatment. Houston, TX, US.
      45. 2014. Integrated analysis and targeting of oncogenic drivers and the anti-tumor immune response to improve outcomes and personalize therapy across the melanoma continuum. Conference. Integrated analysis and targeting of oncogenic drivers and the anti-tumor immune response to improve outcomes and personalize therapy across the melanoma continuum. Houston, TX, US.
      46. 2014. Proteomic Analysis of the PI35-AKT Signaling Pathway in Melanoma. Invited. Proteomic Analysis of the PI35-AKT Signaling Pathway in Melanoma. Houston, TX, US.
      47. 2013. Clinical Next-Generation Sequencing in Advanced Melanoma: The MD Anderson Experience. Conference. Clinical Next-Generation Sequencing in Advanced Melanoma: The MD Anderson Experience. Houston, TX, US.
      48. 2012. Protocol 2012-0470 "Phase I/lb study of SAR260301 (P13K-beta inhibitor) as monotherapy in patients with advanced solid tumors, and in combination with vemurafenib in patients with metastatic BRAF-mutant melanoma" Details & Rationale. Conference. Protocol 2012-0470 "Phase I/lb study of SAR260301 (P13K-beta inhibitor) as monotherapy in patients with advanced solid tumors, and in combination with vemurafenib in patients with metastatic BRAF-mutant melanoma" Details & Rationale. Houston, TX, US.
      49. 2012. Targeted Therapy for Melanoma, 2012. Conference. MDACC Medical Oncology and Hematology Symposium. Houston, TX, US.
      50. 2012. The role of the PI3K-AKT pathway in Melanoma. Conference. The role of the PI3K-AKT pathway in Melanoma. Houston, TX, US.
      51. 2012. The role of the PI3K-AKT pathway in Melanoma. Conference. The role of the PI3K-AKT pathway in Melanoma. Houston, TX, US.
      52. 2012. The role of the PI3K-AKT pathway in Melanoma. Conference. The role of the PI3K-AKT pathway in Melanoma. Houston, TX, US.
      53. 2012. Molecular Biology of Melanoma: Prognostic and Predictive Factors. Conference. Molecular Biology of Melanoma: Prognostic and Predictive Factors. Houston, TX, US.
      54. 2012. A view to the future: Personalized Therapy for Melanoma. Conference. U.T. MD Anderson Cancer Center. Houston, TX, US.
      55. 2011. The Development of Rational Targeted Therapy for Melanoma. Conference. The Development of Rational Targeted Therapy for Melanoma. Houston, TX, US.
      56. 2011. Resistance to MAPK Pathway Inhibition in Melanoma. Conference. Resistance to MAPK Pathway Inhibition in Melanoma. Houston, TX, US.
      57. 2011. A view to the future: Personalized therapy for cancer. Conference. A view to the future: Personalized therapy for cancer. Houston, TX, US.
      58. 2011. Targeted Therapy for Melanoma. Conference. Targeted Therapy for Melanoma. Houston, TX, US.
      59. 2011. Integrated analysis of signaling pathways in Melanoma. Conference. Integrated analysis of signaling pathways in Melanoma. Houston, TX, US.
      60. 2011. A New Era for Melanoma: Targeted Therapy for BRAF. Conference. A New Era for Melanoma: Targeted Therapy for BRAF. Houston, TX, US.
      61. 2011. Molecular biology and therapy of melanoma brain metastases. Conference. Molecular biology and therapy of melanoma brain metastases. Houston, TX, US.
      62. 2011. The Molecular Biology and Therapy of Melanoma Brain Metastases: A Phase II Trial of GSK2118436 for BRAF-Mutant melanoma Patients with Brain Metastases (BRF113929). Conference. Melanoma Medical Oncology Grand Rounds. Houston, TX, US.
      63. 2011. Regulation and Function of the P13K/AKT Pathway in Melanoma. Conference. Regulation and Function of the P13K/AKT Pathway in Melanoma. Houston, TX, US.
      64. 2010. Systemic Therapy for Melanoma. Conference. Current Concepts in Head and Neck Surgery. Houston, TX, US.
      65. 2010. Emerging challenges for personalized cancer therapy: insights from studies of the PI3K-AKT pathway. Conference. Symposia on Cancer Research 2010. Houston, TX, US.
      66. 2010. Targeted therapy in melanoma-lessons learned and future directions. Conference. Targeted therapy in melanoma-lessons learned and future directions. New York, NY, US.
      67. 2010. Overcoming Resistance to MAPK Pathway Inhibitors in Melanoma. Conference. Overcoming Resistance to MAPK Pathway Inhibitors in Melanoma. Houston, TX, US.
      68. 2010. A new paradigm- personalized therapy for melanoma. Conference. A new paradigm- personalized therapy for melanoma. Houston, TX, US.
      69. 2009. A view to the future- the development of targeted therapy for melanoma. Conference. A view to the future- the development of targeted therapy for melanoma. Houston, TX, US.
      70. 2009. Evaluation of targeted therapies for BRAF-mutant melanoma. Conference. Evaluation of targeted therapies for BRAF-mutant melanoma. Houston, TX, US.
      71. 2009. Developing Rational Targeted Therapy Approaches for Melanoma. Conference. Developing Rational Targeted Therapy Approaches for Melanoma. Houston, TX, US.
      72. 2009. Integrated Analysis of Mutations and Activation of the PI3K-AKT Pathway in Cancer. Conference. Integrated Analysis of Mutations and Activation of the PI3K-AKT Pathway in Cancer. Houston, TX, US.
      73. 2008. Update on Melanoma: New Molecular Insights and Therapies. Conference. Update on Melanoma: New Molecular Insights and Therapies. Houston, TX, US.
      74. 2008. Development of Rational Targeted Therapy Approaches for Melanoma: Project Update. Conference. Development of Rational Targeted Therapy Approaches for Melanoma: Project Update. Houston, TX, US.
      75. 2008. The Development of Rational Targeted Therapy for Advanced Melanoma. Conference. The Development of Rational Targeted Therapy for Advanced Melanoma. Houston, TX, US.
      76. 2008. How to find a balance between lab work, personal life, and academics through the MD/PhD program, residency, fellowship, and beyond. Conference. How to find a balance between lab work, personal life, and academics through the MD/PhD program, residency, fellowship, and beyond. Houston, TX, US.
      77. 2007. Assessing Protein Networks by Reverse Phase Protein Arrays. Invited. UTHSC Scleroderma and Fibrosing Disorder Research Seminar. Houston, TX, US.
      78. 2007. How to Analyze a High- Throughput Screen. Conference. How to Analyze a High- Throughput Screen. Houston, TX, US.
      79. 2000. Studies of the tumor suppressor MMAC/PTEN in human glioblastoma multiforme and prostate cancer cells. Conference. Studies of the tumor suppressor MMAC/PTEN in human glioblastoma multiforme and prostate cancer cells. Houston, TX, US.
      80. 2000. The functional role of the tumor suppressor MMAC/PTEN in glioblastoma multiforme and prostate cancer cells. Conference. The functional role of the tumor suppressor MMAC/PTEN in glioblastoma multiforme and prostate cancer cells. Houston, TX, US.

      Regional Presentations

      1. 2021. The role of oxidative phosphorylation (OXPHOS) in metastasis and therapeutic resistance in melanoma. Conference. The role of oxidative phosphorylation (OXPHOS) in metastasis and therapeutic resistance in melanoma. Virtual, US.
      2. 2017. New Paradigms and New Questions: The Rapidly Evolving Landscape and Management of Melanoma. Invited. New Paradigms and New Questions: The Rapidly Evolving Landscape and Management of Melanoma. Dallas, TX, US.
      3. 2015. Molecular Biology and Therapy of Melanoma CNS Metastasis. Conference. UTMB Health. Galveston, TX, US.
      4. 2014. Debate: Should Patients with BRAFmut metastatic melanoma get a BRAF+/- MEK inhibitor first-line? Response "Yes". Conference. 1st Annual Summit on Practical and Emerging Trends. Dallas, TX, US.
      5. 2014. NRAS and CDK targeted therapy in melanoma. Conference. Oncology Meeting Innovations. Dallas, TX, US.

      National Presentations

      1. 2026. Evolving Treatment Paradigms in Melanoma: Targeted and Immune-Based Approaches. Invited. Indy Precision Oncology Symposium (IPOS). Carmel, IN, US.
      2. 2026. Rational Approaches to Melanoma Therapy. Invited. NCI- Annual PDX meeting. San Diego, California, US.
      3. 2026. Molecular Targets and Therapies. Invited. Melanoma US Focus Meeting. San Diego, California, US.
      4. 2025. Melanoma central nervous system (CNS) metastases- advances in understanding and outcomes. Invited. Seminar in Clinical Research. New York, NY, US.
      5. 2023. Integrating the Latest Evidence in Melanoma Care to Address Health Equity. Invited. Talem Health. Trumbull, CT, US.
      6. 2023. The Final Frontier: Advancing Understanding and Outcomes in Melanoma CNS Metastases. Invited. Melanoma Lecture Series. Boston, MA, US.
      7. 2023. Evolving Therapeutic Landscape, Outcomes and Prognostic Factors for Melanoma CNS Disease. Conference. 2023 Brain Metastasis Symposium. Virtual, US.
      8. 2022. Unique features and dependencies of brain metastases. Conference. AACR Special Conference on Cancer Metastasis: Microenvironment and Metastasis. Portland, OR, US.
      9. 2022. Overview of key barriers to understanding the pathophysiology of brain metastases and improving disease outcome. Conference. Workshop on Shaping the Landscape of Brain Metastases Research. Virtual, US.
      10. 2022. The Final Frontier - Advances in the Understanding and Treatment of Melanoma Brain Metastasis. Invited. The Final Frontier - Advances in the Understanding and Treatment of Melanoma Brain Metastasis. Virtual, US.
      11. 2022. Personalized strategies targeting BCL2 family proteins to overcome acquired resistance in BRAF-mutant melanoma. Conference. Personalized strategies targeting BCL2 family proteins to overcome acquired resistance in BRAF-mutant melanoma. Virtual, US.
      12. 2021. Clinical advances in CNS metastases: How novel therapies are revolutionizing the management of CNS metastases. Conference. Clinical advances in CNS metastases: How novel therapies are revolutionizing the management of CNS metastases. Virtual/Boston, MA, US.
      13. 2021. Molecular Targets & Strategies for Melanoma Brain Metastases. Conference. Molecular Targets & Strategies for Melanoma Brain Metastases. Virtual/Washington, DC, US.
      14. 2021. Welcome and Introduction. Conference. Welcome and Introduction. Virtual/Washington, DC, US.
      15. 2021. Plan for Collaboration/Meeting Wrap Up. Conference. Plan for Collaboration/Meeting Wrap Up. Virtual/Washington, DC, US.
      16. 2021. Role of Systemic Therapy in the Management of Brain Metastases: Melanoma Metastases. Conference. The Society for Neuro-Oncology. Virtual, US.
      17. 2021. Moving the Needle: Advances in Brain Metastases Management. Conference. Moving the Needle: Advances in Brain Metastases Management. Virtual, US.
      18. 2021. Metabolic and Immunologic Pathways of Metastasis. Conference. AACR Annual Meeting 2021. Virtual, US.
      19. 2021. Evolving Treatment Approaches for Patients with Locally Advanced or Regionally Metastatic Melanoma. Conference. Roche/GNE. Virtual, US.
      20. 2021. Breakthroughs in the Understanding and Treatment of Melanoma Brain Metastasis. Invited. Breakthroughs in the Understanding and Treatment of Melanoma Brain Metastasis. Virtual, US.
      21. 2021. Breakthroughs in the understanding and treatment of CNS metastases from melanoma. Conference. Cancer Institute Forum. Virtual, US.
      22. 2021. Breakthroughs in the understanding and treatment of CNS metastases from melanoma. Invited. Breakthroughs in the understanding and treatment of CNS metastases from melanoma. Virtual, US.
      23. 2021. Recent Advances & Novel Approaches for Metastatic Melanoma. Conference. 2021 Practical Applications of New Agents in Oncology (PANAO) Conference. Virtual, US.
      24. 2021. The Final Frontier: Advances in the Understanding and Treatment of Melanoma Brain Metastasis. Invited. The Final Frontier: Advances in the Understanding and Treatment of Melanoma Brain Metastasis. Virtual, US.
      25. 2020. Applying Precision Medicine for Solid Tumors in Federal and Public Health Settings. Conference. Melanoma and Patient-Centered Care. Virtual, US.
      26. 2020. Systemic Therapy for Stage IV Melanoma: Current Standards, Questions, and Investigations. Conference. Melanoma: Expert Guidance and Resources to Optimize Care Along the Treatment Continuum. Virtual, US.
      27. 2020. Addressing Precision Medicine Across Solid Tumors in Federal and Public Health Settings. Conference. Melanoma/Patient Survivorship. Virtual, US.
      28. 2020. Advances in the Understanding and Treatment of CNS Metastases. Invited. Advances in the Understanding and Treatment of CNS Metastases. Virtual, US.
      29. 2020. The Final Frontier-Advances in the Understanding and Treatment of Melanoma Brain Metastases. Invited. The Final Frontier-Advances in the Understanding and Treatment of Melanoma Brain Metastases. Durham, NC, US.
      30. 2020. Breakthroughs in the Understanding and Treatment of Brain Metastases. Conference. Clinical Hematology & Oncology Conference: 2020. San Diego, CA, US.
      31. 2020. New Paradigm in the Treatment of Melanoma Brain Metastases: Are We Finally Making Progress?. Conference. New Paradigm in the Treatment of Melanoma Brain Metastases: Are We Finally Making Progress?. Steamboat Springs, CO, US.
      32. 2020. Front-line Therapy for Disseminated Melanoma: Current Standards and Future Directions. Conference. Front-line Therapy for Disseminated Melanoma: Current Standards and Future Directions. Steamboat Springs, CO, US.
      33. 2019. Relapsed/Refractory Melanoma-Where Do We Stand?. Conference. Relapsed/Refractory Melanoma-Where Do We Stand?. Salt Lake City, UT, US.
      34. 2019. Melanoma Metastasis: Models and Mechanisms. Conference. Melanoma Metastasis: Models and Mechanisms. Salt Lake City, UT, US.
      35. 2019. Update on Melanoma Brain Metastasis Initiatives. Conference. Update on Melanoma Brain Metastasis Initiatives. Philadelphia, PA, US.
      36. 2019. Current Treatments and Investigations for CNS Metastases. Conference. FDA Brain Metastasis Workshop. Bethesda, MD, US.
      37. 2019. Unraveling the role of metabolism in melanoma. Invited. Unraveling the role of metabolism in melanoma. Pittsburgh, PA, US.
      38. 2019. Front-Line Therapy for Disseminated Melanoma: Current Standards and Future Directions. Conference. Front-Line Therapy for Disseminated Melanoma: Current Standards and Future Directions. Breckenridge, CO, US.
      39. 2019. New Paradigm in the Treatment of Melanoma Brain Metastases: Are we Finally Making Progress?. Conference. New Paradigm in the Treatment of Melanoma Brain Metastases: Are we Finally Making Progress?. Breckenridge, CO, US.
      40. 2019. Distinct immune and molecular features of melanoma brain metastases. Conference. Distinct immune and molecular features of melanoma brain metastases. Houston, TX, US.
      41. 2018. Integration of Immunotherapy and Oncogenic Signaling Pathways in Cancer. Conference. Integration of Immunotherapy and Oncogenic Signaling Pathways in Cancer. District of Columbia, WA, US.
      42. 2018. Targeting BRAF-mutant melanoma brain metastasis. Conference. Targeting BRAF-mutant melanoma brain metastasis. Washington, DC, US.
      43. 2018. Melanoma Brain Metastases: Targeted Therapy Clinical Trials. Conference. Melanoma Brain Metastases: Targeted Therapy Clinical Trials. Tampa, FL, US.
      44. 2018. Molecular Biology of Melanoma Brain Metastases. Conference. Molecular Biology of Melanoma Brain Metastases. Tampa, FL, US.
      45. 2018. Integrated Interrogation of Oncogenic Signaling Pathways, Immunology, and Heterogeneity in Cancer. Conference. Integrated Interrogation of Oncogenic Signaling Pathways, Immunology, and Heterogeneity in Cancer. Orlando, FL, US.
      46. 2018. Genetic and Clinical Variance in Response to Melanoma Treatment. Conference. Genetic and Clinical Variance in Response to Melanoma Treatment. New York City, NY, US.
      47. 2018. Front-Line Therapy for Disseminated Melanoma: Current Standards and Future Directions. Conference. Front-Line Therapy for Disseminated Melanoma: Current Standards and Future Directions. Breckenridge, CO, US.
      48. 2018. BIG News! The role of obesity in melanoma. Invited. BIG News! The role of obesity in melanoma. Philadelphia, PA, US.
      49. 2017. Integration of Immunotherapy and Oncogenic Signaling Pathways in Cancer. Conference. Integration of Immunotherapy and Oncogenic Signaling Pathways in Cancer. Oxen Hill, MD, US.
      50. 2017. The PI3K-AKT Pathway in Melanoma-Metastasis, Metabolism, and Resistance. Invited. Divisional Grand Rounds. New York, NY, US.
      51. 2016. New Paradigms-The Rapidly Evolving Understanding and Management of Melanoma. Invited. New Paradigms-The Rapidly Evolving Understanding and Management of Melanoma. Tifton, GA, US.
      52. 2016. The Role of the PI3K-AKT Pathway in Brain Metastasis and Therapeutic Resistance in Melanoma. Invited. Athens, GA, US.
      53. 2016. Immunotherapy Trials and Translational Research for LMD. Conference. Immunotherapy Trials and Translational Research for LMD. Pittsburgh, PA, US.
      54. 2016. New-Paradigms-The Rapidly Evolving Landscape of Melanoma. Conference. New-Paradigms-The Rapidly Evolving Landscape of Melanoma. Dublin, OH, US.
      55. 2016. Decoding the disease: unravelling the mutations and pathways driving melanoma. Conference. Decoding the disease: unravelling the mutations and pathways driving melanoma. Los Angeles, CA, US.
      56. 2015. The role and therapeutic potential of Oxidative Phosphorylation in melanoma. Conference. The role and therapeutic potential of Oxidative Phosphorylation in melanoma. Philadelphia, PA, US.
      57. 2015. Role of the PI3K-AKT pathway in melanoma brain metastasis. Conference. Role of the PI3K-AKT pathway in melanoma brain metastasis. Philadelphia, PA, US.
      58. 2015. Molecular Biology and Testing in the Oncology Clinic. Conference. College of American Pathologists. Nashville, TN, US.
      59. 2015. Translating the Molecular Biology of Melanoma in the Clinic. Conference. Translating the Molecular Biology of Melanoma in the Clinic. Chicago, IL, US.
      60. 2015. Molecular Profiling in Melanoma, 2015. Conference. Molecular Profiling in Melanoma, 2015. Cleveland, OH, US.
      61. 2015. The Rapidly Evolving Landscapes of Systemic Therapies for Advanced Melanoma: Achievements, Challenges, and Opportunities. Conference. The Rapidly Evolving Landscapes of Systemic Therapies for Advanced Melanoma: Achievements, Challenges, and Opportunities. Mount Laurel, NJ, US.
      62. 2015. Emerging Treatments for Metastatic Melanoma. Conference. Emerging Treatments for Metastatic Melanoma. New York, NY, US.
      63. 2015. Opportunities and needs for molecular imaging in melanoma. Conference. Opportunities and needs for molecular imaging in melanoma. San Diego, CA, US.
      64. 2015. The Multi-Faceted Roles of the PI3K-AKT Pathway in the Pathogenesis and Therapeutic Resistance of Melanoma. Invited. Philadelphia, PA, US.
      65. 2014. Melanoma signaling pathways: clinical outcomes, therapeutic resistance, and metabolism. Conference. Melanoma signaling pathways: clinical outcomes, therapeutic resistance, and metabolism. Tampa, FL, US.
      66. 2014. Molecular Biology and Testing in the Oncology Clinic. Conference. College of American Pathologists. Chicago, IL, US.
      67. 2014. Overview of Metastatic Melanoma, including Staging and Diagnosing Current Standing of Care. Conference. Overview of Metastatic Melanoma, including Staging and Diagnosing Current Standing of Care, US.
      68. 2014. Intersection of PI3K-AKT Pathway Signaling, Metabolism and Therapeutic Resistance. Conference. Intersection of PI3K-AKT Pathway Signaling, Metabolism and Therapeutic Resistance. San Diego, CA, US.
      69. 2014. The role of the PI3K-AKT pathway in melanoma. Invited. The role of the PI3K-AKT pathway in melanoma. San Diego, CA, US.
      70. 2013. Molecular Biology and Therapy of Melanoma Brain Metastases. Invited. Molecular Biology and Therapy of Melanoma Brain Metastases. New York, NY, US.
      71. 2013. Recurrent Mutations in Melanoma. Conference. Imedex. Baltimore, MD, US.
      72. 2013. The Role of the PI3K-AKT Pathway in Melanoma. Invited. Nashville, TN, US.
      73. 2013. Melanoma 2013: New Strategies and Treatments. Conference. The 24th Annual Mary Mulready Sullivan Oncology Symposium. Hartford, CT, US.
      74. 2013. Molecular Testing in Melanoma, 2013. Conference. MD Anderson Cancer Center. Houston, TX, US.
      75. 2013. The Role of the PI3K-AKT Pathway in Melanoma. Invited. Pittsburgh, PA, US.
      76. 2013. Identifying therapeutic targets for melanoma brain metastases. Conference. Melanoma Research Alliance. Washington, DC, US.
      77. 2012. The role of the PI3K-AKT Pathway in Melanoma. Invited. Philadelphia, PA, US.
      78. 2012. The role of the PI3K-AKT pathway in melanoma. Invited. Boston, MA, US.
      79. 2012. Molecular and Clinical Correlates of PTEN Expression in Melanoma. Conference. 103rd Annual AACR Meeting: Education Session. Chicago, IL, US.
      80. 2012. The Role of the PI3K-AKT Pathway in Melanoma. Invited. Salt Lake City, UT, US.
      81. 2011. Beyond BRAF: Additional molecular targets in Melanoma. Conference. Beyond BRAF: Additional molecular targets in Melanoma. Washington, DC, US.
      82. 2011. Evaluation of BRAF/NRAS Mutations an PTEN expression in advanced Melanoma. Conference. Evaluation of BRAF/NRAS Mutations an PTEN expression in advanced Melanoma. Boston, MA, US.
      83. 2011. Beyond BRAF: Additional molecular targets in Melanoma. Conference. Advanced Melanoma: Biology and Treatment. Boston, MA, US.
      84. 2011. A View to the Future-Personalized Therapy for Melanoma. Conference. Melanoma Research Foundation Northwest Melanoma Symposium. Seattle, WA, US.
      85. 2011. A View to the Future: The Treatment of Melanoma, 2011. Conference. Northern Trust Ft. Lauderdale. Ft. Lauderdale, FL, US.
      86. 2011. Integrated Analysis of Signaling Pathways in Melanoma. Conference. 102nd AACR Annual Meeting. Orlando, FL, US.
      87. 2011. Novel Targets in Melanoma. Conference. 102nd AACR Annual Meeting. Orlando, FL, US.
      88. 2010. Targeted therapy for Melanoma - Where do we go from here?. Conference. Southwest Oncology Group Fall 2010 Group Meeting. Chicago, IL, US.
      89. 2010. Reverse phase protein array (RPPA) analysis to characterize protein signaling networks in melanoma. Conference. National Melanoma SPORE Summer Workshop. Houston, TX, US.
      90. 2010. Integrated Clinical and Molecular Analysis of the PI3K-AKT Pathway in Melanoma. Invited. Interdisciplinary Melanoma Cooperative Program. New York, NY, US.
      91. 2009. Assessment of AKT activation in Melanoma: Relation to Mutations, Anatomic Sites, and Clinical Outcomes. Conference. SPORE in Skin Cancer Spring Talk Series. Philadelphia, PA, US.
      92. 2009. Assessment of AKT activation in Melanoma: Relation to Mutations, anatomic sites, and clinical outcomes. Invited. SPORE in Skin Cancer Spring Talk Series. Philadelphia, PA, US.
      93. 2007. Functional Proteomics for Development of Individualized Cancer Therapy. Conference. Functional Proteomics for Development of Individualized Cancer Therapy, US.
      94. 2007. The Biology of AKT in Melanoma. Conference. 15th SPORE Investigators' Workshop. Baltimore, MD, US.
      95. 1999. Biological responses to MMAC/PTEN reintroduction in various human cancers. Conference. 14th Annual M.D. /PhD. Conference. Aspen, CO, US.
      96. 1999. Different biological responses to MMAC/PTEN reintroduction in various human cancers. Conference. Keystone Symposium: Specificity in Signal Transduction. Keystone, CO, US.

      International Presentations

      1. 2025. Melanoma brain metastases, advances in systemic treatment. Invited. Santiago, CL.
      2. 2025. Targeted therapy for and molecular biology of melanoma brain metastases. Invited. World Melanoma Congress/EADO. Athens, GR.
      3. 2025. Advances in Melanoma Treatment. Invited. Virtual, US.
      4. 2024. Incidence and risk factors for central nervous system (CNS) metastasis (met) in stage IIImelanoma patients (pts) treated with adjuvant (ADJ) anti-PD1 immunotherapy (IMT). Poster.
      5. 2022. Q&A/ Panel Discussion. Conference. The 19th International Congress of the Society for Melanoma Research. Edinburgh, GB.
      6. 2022. Management of Melanoma CNS Metastases: Progress, Challenges & Opportunities. Conference. The 19th International Congress of the Society for Melanoma Research. Edinburgh, GB.
      7. 2022. Advances in Systemic Treatments for Melanoma Brain Metastases. Conference. International Melanoma Working Group (IMWG). Virtual, US.
      8. 2022. New Paradigms for Melanoma Central Nervous System (CNS) Metastases. Conference. IX Workshop on Melanoma Models and Translational Oncology. Rio de Janeiro, BR.
      9. 2021. CNS Metastasis from Melanoma: Progress, Insights and Opportunities. Conference. Hallmarks of Skin Cancer Meeting. Virtual, US.
      10. 2021. Challenging Cases in Melanoma. Conference. Challenging Cases in Melanoma. Virtual, US.
      11. 2021. ASCO updates in metastatic and adjuvant treatment of melanoma. Conference. 2021 Chinese Master Melanoma Summit for Education & Research. Virtual, CN.
      12. 2021. Management of brain metastasis. Conference. Melanoma World Society/EADO. Virtual, US.
      13. 2021. New insights into the unique features and pathogenesis of brain metastases. Conference. Melanoma World Society/EADO. Virtual, US.
      14. 2021. Advances in the Understanding and Treatment of Melanoma Brain Metastases. Conference. Hallmarks of Skin Cancer. Virtual, US.
      15. 2019. Novel immune, molecular and metabolic features of melanoma brain metastases: implications for therapeutic development. Conference. Novel immune, molecular and metabolic features of melanoma brain metastases: implications for therapeutic development. Kyoto, JP.
      16. 2019. Will Targeted Therapy Replace Whole Brain Radiation (WBXRT) in Melanoma Brain Metastases?. Conference. Will Targeted Therapy Replace Whole Brain Radiation (WBXRT) in Melanoma Brain Metastases?. Chicago, US.
      17. 2018. Emerging strategies for combination immunotherapy in melanoma. Conference. Emerging strategies for combination immunotherapy in melanoma. Naples, IT.
      18. 2018. Breakthroughs in systemic therapy for brain metastases. Conference. Breakthroughs in systemic therapy for brain metastases. Melbourne, AU.
      19. 2018. Brain Metastases: Intrathecal Therapy and Targeted Therapy. Conference. Brain Metastases: Intrathecal Therapy and Targeted Therapy. Edinburgh.
      20. 2017. BIG NEWS: The Obesity Paradox of Melanoma. Conference. BIG NEWS: The Obesity Paradox of Melanoma. Naples, IT.
      21. 2017. The Role of Metabolism in Therapy and Brain Metastasis in Melanoma. Conference. The Role of Metabolism in Therapy and Brain Metastasis in Melanoma. Florence, IT.
      22. 2017. Integrating immune and targeted therapy in melanoma. Conference. Karolinska Institutet Workshop. Stockholm, SE.
      23. 2017. COMBI-MB: a phase 2 study of combination dabrafenib (D) and trametinib (T) in patients (pts) with BRAF V600-mutant (mut) melanoma brain metastases (MBM). Conference. COMBI-MB: a phase 2 study of combination dabrafenib (D) and trametinib (T) in patients (pts) with BRAF V600-mutant (mut) melanoma brain metastases (MBM). Chicago, US.
      24. 2016. In vivo E2F reporting on efficacious dosing schedule of MEK plus CDK inhibition in melanoma. Conference. In vivo E2F reporting on efficacious dosing schedule of MEK plus CDK inhibition in melanoma. Boston, US.
      25. 2016. Can neoadjuvant targeted therapy beat standard of care therapy?. Conference. Can neoadjuvant targeted therapy beat standard of care therapy?. Boston, US.
      26. 2016. Treatment with neoadjuvant + adjuvant dabrafenib and trametinib (D+T) is associated with improved relapse-free survival (RFS) versus standard of care (SOC) therapy in patients with high-risk resectable BRAF-mutant melanoma. Conference. Treatment with neoadjuvant + adjuvant dabrafenib and trametinib (D+T) is associated with improved relapse-free survival (RFS) versus standard of care (SOC) therapy in patients with high-risk resectable BRAF-mutant melanoma. Boston, US.
      27. 2016. Patient characteristics associated with ≥36-months clinical benefit with combination dabrafenib and trametinib (D+T) in COMBI-d. Conference. Patient characteristics associated with ≥36-months clinical benefit with combination dabrafenib and trametinib (D+T) in COMBI-d. Boston, US.
      28. 2016. High body mass index (BMI) is associated with improved clinical outcomes in metastatic melanoma patients treated with anti-PD1: differences by gender. Conference. High body mass index (BMI) is associated with improved clinical outcomes in metastatic melanoma patients treated with anti-PD1: differences by gender. Boston, US.
      29. 2016. Co-targeting HGF-cMET signaling with MEK inhibitors in metastatic uveal melanoma. Conference. Co-targeting HGF-cMET signaling with MEK inhibitors in metastatic uveal melanoma. Boston, US.
      30. 2016. Leptomeningeal disease (LMD) from metastatic melanoma: a single institution experience and predictors of survival. Conference. Leptomeningeal disease (LMD) from metastatic melanoma: a single institution experience and predictors of survival. Boston, US.
      31. 2016. Stromal neuregulin-1 modulates the response to MEK inhibitors in WT BRAF/WT NRAS (WT/WT) melanomas. Conference. Stromal neuregulin-1 modulates the response to MEK inhibitors in WT BRAF/WT NRAS (WT/WT) melanomas. Boston, US.
      32. 2016. The PI3K-AKT Pathway in Melanoma Pathogenesis, Progression, and Resistance. Invited. Essen, DE.
      33. 2016. Melanoma brain metastases-Insights into the Molecular Biology and Therapeutic Perspectives. Conference. Melanoma brain metastases-Insights into the Molecular Biology and Therapeutic Perspectives. Dresden, DE.
      34. 2016. Molecular Targets and Therapy. Conference. Molecular Targets and Therapy. Chicago, US.
      35. 2016. Now It's Personal: Individualizing Treatments in Melanoma. Conference. Now It's Personal: Individualizing Treatments in Melanoma. Amsterdam, NL.
      36. 2016. Onward and Upward: Future Landscape in Melanoma. Conference. Onward and Upward: Future Landscape in Melanoma. Amsterdam, NL.
      37. 2015. Immunologic and metabolic consequences of the Pl3K-AKT pathway in melanoma. Conference. Melanoma Bridge 2015. Naples, IT.
      38. 2015. The Role of the PI3K-AKT Pathway in Melanoma Brain Metastasis. Conference. The Role of the PI3K-AKT Pathway in Melanoma Brain Metastasis. San Francisco, US.
      39. 2015. Integrated Risk Modeling of Primaries. Conference. International Melanoma Working Group (IMWG). Marseille, IT.
      40. 2015. Targeted Therapy for Melanoma: A Personalized Approach. Conference. International Melanoma Working Group (IMWG). Houston, US.
      41. 2015. Target BRAF V600: Response & Resistance to BRAF/MEK Inhibition. Conference. Target BRAF V600: Response & Resistance to BRAF/MEK Inhibition. Chicago, US.
      42. 2015. Targeting the PI3K-AKT Pathway in Melanoma. Conference. International Melanoma Working Group (IMWG), PL.
      43. 2015. Clinical and Therapeutic Significance of the PI3K-AKT Pathway in Melanoma. Conference. Clinical and Therapeutic Significance of the PI3K-AKT Pathway in Melanoma. Vancouver, US.
      44. 2014. The multi-faceted roles of the PI3K-AKT pathway in melanoma. Conference. The multi-faceted roles of the PI3K-AKT pathway in melanoma, IT.
      45. 2014. Melanoma- Onward and Upward. Conference. Melanoma- Onward and Upward. Milwaukee, US.
      46. 2014. Molecular Basis for Combinatorial Strategies in Melanoma. Conference. Molecular Basis for Combinatorial Strategies in Melanoma, US.
      47. 2013. Systemic Therapy for Melanoma, 2013. Conference. Systemic Therapy for Melanoma, 2013. Quito, EC.
      48. 2013. Targeting Melanoma Brain Metastases. Conference. International Melanoma Working Group (IMWG). Chantilly, US.
      49. 2013. Molecular Pathology of Cutaneous Melanoma: A Basic Science Perspective. Conference. Molecular Pathology of Cutaneous Melanoma: A Basic Science Perspective. San Diego, US.
      50. 2013. Scientific Discussant. Conference. Scientific Discussant. Chicago, US.
      51. 2012. The MAP Kinase Pathway in Melanoma: A Primer for Clinicians. Conference. University of Cincinnati, Medical Learning Institute, Inc., and Center of Excellence Media, LLC in collaboration with Core Principle Solutions, LLC. Montreal, CA.
      52. 2011. Regulation and Function of the PI3K Pathway in Melanoma. Conference. Regulation and Function of the PI3K Pathway in Melanoma. Bordeaux, FR.
      53. 2011. BRAF Inhibition in Melanoma Brain Metastases. Conference. International Melanoma Working Group Symposium. Barcelona, ES.
      54. 2010. B-RAFi GSK2118346 Presurgical Evaluation in Patients with Operable Brain Metastasis and Proven V600E Mutations (Protocol iMWG 02). Conference. International Melanoma Working Group (IMWG). Naples, IT.
      55. 2010. Personalized Targeted Therapy for Cancer. Conference. Joint Symposium on Cancer Research. Barretos, BR.
      56. 2010. The Molecular Biology of Melanoma. Conference. Joint Symposium on Cancer Research. Barretos, BR.
      57. 2010. Perspectives on Systemic Therapy for Melanoma. Conference. Joint Symposium on Cancer Research. Barretos, BR.
      58. 2010. Mechanisms of Resistance to AZD6244 in BRAF-Mutant Melanoma. Conference. Tumor metabolism and P13K signaling symposium. Manchester, GB.

      Formal Peers

      1. 2026. Melanoma in Minutes: Evidence-Driven Care for Improved Patient Outcomes. Houston, Texas, US.
      2. 2024. Laboratory and Project Management and Grant writing. Houston, Texas, US.
      3. 2023. Oh the Places You'll Go! My Experience as a Physician-Scientist (So Far). Conference, US.
      4. 2023. MD/PhD Training Programs and the Physician-Scientist Career Pathway. Invited. Virtual, US.
      5. 2021. Mastering Melanoma: A Symposium for Patients and Caregivers. Conference. Virtual, US.
      6. 2021. MD/PhD Training Programs and the Physician-Scientist Career Pathway. Conference. Virtual, US.
      7. 2021. Big Survey. Conference. Houston, TX, US.
      8. 2020. Metastatic Melanoma, 2020. Conference. Houston, TX, US.
      9. 2019. Immunotherapy for Stage IV Melanoma. Invited. Phoenix, AZ, US.
      10. 2017. Targeted Therapy of Melanoma. Conference. Houston, TX, US.
      11. 2016. Systemic Therapy for Melanoma. Conference. Houston, TX, US.
      12. 2016. Controversies in Melanoma-BRAF Mutant Disease. Conference. Houston, TX, US.
      13. 2016. Target Therapy for BRAF Mutant Melanoma. Conference. Houston, TX, US.
      14. 2014. Systemic Therapy for Melanoma, 2014: How did we get here and where are we going?. Invited. Milwaukee, WI, US.
      15. 2013. Best of ASCO 2013 Annual Meeting: Melanoma. Conference. Houston, TX, US.
      16. 2012. From the Bench to the Bedside- Targeting BRAF in Melanoma. Conference. Houston, TX, US.
      17. 2009. The development of rational targeted therapy for melanoma. Invited. Houston, TX, US.
      18. 2009. The Development of Rational Targeted Therapy for Melanoma. Invited. Waukesha, WI, US.
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      Grant & Contract Support

      Date: 2026 - 2031
      Title:T32 Research Training in Academic Medical Oncology
      Funding Source:National Cancer Institute
      Role:PI
      ID:2T32CA009666-31A1
      Date: 2025 - 2028
      Title:Overcoming metastasis and therapeutic resistance in melanoma
      Funding Source:Dr. Miriam and Sheldon Adelson Medical Research Foundation
      Role:PI
      ID:FP27220
      Date: 2025 - 2028
      Title:Functional Proteomics RPPA Platform at MD Anderson
      Funding Source:Adelson Medical Research Foundation
      Role:PI
      ID:FP27062
      Date: 2025 - 2027
      Title:The role of oral microbiota in metastatic brain tumors
      Funding Source:National Cancer Institute
      Role:Mentor
      ID:1 K99 CA296780-01
      Date: 2024 - 2029
      Title:The University of Texas MD Anderson Cancer Center SPORE in Melanoma
      Funding Source:NIH
      Role:PI
      ID:FP20546
      Date: 2024 - 2028
      Title:Rational Approaches to Melanoma Therapy
      Funding Source:NIH/NCI
      Role:Co-PI
      ID:RSG-23-1155993-01-MM
      Date: 2024 - 2027
      Title:Multifaceted roles of AXL in shaping tumor immune microenvironment
      Funding Source:American Cancer Society (ACS)
      Role:Co-PI
      ID:RSG-23-1155993-01-MM
      Date: 2023 - 2028
      Title:Personalized targeting of anti-apoptosis pathways to overcome therapeutic resistance in melanoma
      Funding Source:NIH/NCI-The Wistar Institute
      Role:Co-PI
      ID:FP00017981
      Date: 2023 - 2025
      Title:Elucidating the Role of Oral Microbiome in Metastatic Brain Tumors
      Funding Source:American Brain Tumor Association
      Role:Lead Mentor
      Date: 2022 - 2025
      Title:Overcoming Metastasis and Therapeutic Resistance in Melanoma
      Funding Source:Dr. Miriam and Sheldon G. Adelson Medical Research Foundation
      Role:PI
      ID:FP17016/AWD00006993
      Date: 2022 - 2025
      Title:Functional Proteomics RPPA Platform at MD Anderson
      Funding Source:Dr. Miriam and Sheldon G. Adelson Medical Research Foundation
      Role:PI
      ID:FP17015/AWD00006992
      Date: 2022 - 2025
      Title:Tumor and Microenvironment Inflammatory Pathways as Targets for Improvement of Melanoma Patient Outcomes
      Funding Source:Dr. Miriam and Sheldon G Adelson Research Foundation
      Role:PI
      ID:FP17003
      Date: 2022 - 2026
      Title:ME210230P1 - Melanoma Academy Leadership Award
      Funding Source:Department of Defense (DOD)
      Role:Co-PI
      ID:W81XWH2220054
      Date: 2022 - 2027
      Title:Unraveling dynamic co-evolutions of brain metastasis and the unique brain microenvironment
      Funding Source:NIH/NCI
      Role:Co-PI
      ID:FP00011852_Res1
      Date: 2022 - 2029
      Title:Evaluation of ERRa Inhibition in Melanomas of High Oxidative Phosphorylation
      Funding Source:Lead Pharma
      Role:PI
      ID:LS2020-00057746-JW
      Date: 2022 - 2024
      Title:Evaluation of ABM-1310 in Melanoma Brain Metastasis
      Funding Source:ABM Therapeutics, Inc
      Role:PI
      ID:AWD00006400
      Date: 2022 - 2025
      Title:Multifaceted roles of AXL in shaping the tumor immune microenvironment
      Funding Source:American Cancer Society (UH Prime)
      Role:Principal Investigator-MDACC
      Date: 2021 - 2026
      Title:Unraveling dynamic co-evolutions of brain metastasis and the unique brain microenvironment
      Funding Source:NIH/NCI
      Role:Co-PI
      ID:U54CA261702-01
      Date: 2020 - 2025
      Title:Optimizing Detection and Interventions Against Rare Pre-existing Drug Resistance Mutations
      Funding Source:NIH/NHGRI
      Role:Co-I
      ID:1R01HG011356-02
      Date: 2020 - 2024
      Title:Predictor of response to neoadjuvant therapy in melanoma
      Funding Source:Rising Tide Foundation Clinical Cancer Res
      Role:Co-I
      ID:CCR-20-100 AWD00005366 (Project 12269)
      Date: 2020 - 2023
      Title:Predictor of Response to Neoadjuvant Therapy in Melanoma
      Funding Source:Melanoma Research Alliance
      Role:Co-I
      ID:683873 AWD00005108 (Project 111870)
      Date: 2020 - 2025
      Title:A Convergent Node in Melanoma to Block Multiple Oncogenic Pathways Simultaneously
      Funding Source:NIH/NCI
      Role:Co-I
      ID:1R01CA251608-03
      Date: 2020 - 2025
      Title:UCHL5 as a regulator and therapeutic target in metastatic melanoma
      Funding Source:NIH/NCI
      Role:Co-I
      ID:1R01CA245395-03
      Date: 2020 - 2022
      Title:An ultraconservation-based mutation predictor for occurrence of skin cancers in CLL
      Funding Source:SINF – Sister Institution Network Fund
      Role:Co-PI
      Date: 2020 - 2026
      Title:Research Training in Academic Medical Oncology
      Funding Source:NIH/NCI
      Role:Co-PI
      ID:2T32CA009666-27
      Date: 2020 - 2025
      Title:Targeting oxidative phosphorylation to reduce the incidence and therapeutic resistance of melanoma brain metastasis
      Funding Source:NIH/NCI
      Role:PI
      Date: 2020 - 2023
      Title:Molecular Predictors and Vulnerabilities of Melanoma Brain Metastasis
      Funding Source:American Cancer Society (ACS)
      Role:PI
      ID:134148-MRAT-19-168-01
      Date: 2020 - 2023
      Title:Molecular Predictors and Vulnerabilities of Melanoma Brain Metastasis
      Funding Source:Melanoma Research Alliance
      Role:PI
      ID:687055
      Date: 2019 - 2022
      Title:Improving Outcomes in Refractory Advanced Melanoma
      Funding Source:Adelson Medical Research Foundation
      Role:PI
      ID:AWD00004515
      Date: 2019 - 2022
      Title:Functional Proteomics RPPA Platform
      Funding Source:Adelson Medical Research Foundation
      Role:PI
      ID:AWD00004512
      Date: 2019 - 2026
      Title:The University of Texas MD Anderson SPORE in Melanoma-Parent Grant
      Funding Source:NIH/NCI
      Role:PI
      ID:5P50CA221703-04
      Date: 2019 - 2021
      Title:The University of Texas MD Anderson Cancer Center SPORE in Melanoma-Career Enhancement Program (CEP) Award
      Funding Source:NIH/NCI
      Role:Mentor
      ID:P50CA221703
      Date: 2018 - 2023
      Title:Integration of Clinical, Molecular, and Immune Features to Improve Risk Stratification and Outcomes in Melanoma Patients with Sentinel Lymph Node Metastasis
      Funding Source:DOD/Congressionally Directed Medical Research Programs (DOD/CDMRP)
      Role:Co-PI
      ID:CA170374P2
      Date: 2018 - 2022
      Title:Biomarker-directed proof-of-concept phase I trial of the first-in-class OXPHOS inhibitor IACS-010759 in patients with advanced solid tumors
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:Collaborator
      Date: 2018 - 2021
      Title:Integrative molecular and immune analysis of a Phase I/II trial of GSK2636771 in combination with pembrolizumab in metastatic melanoma patients with PTEN loss
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:PI
      ID:RP180467
      Date: 2017 - 2022
      Title:Project 1, Targeting the PI3K Pathway to Overcome Resistance to Immunotherapy in Melanomas with Loss of Pten
      Funding Source:NIH/NCI
      Role:Co-Leader
      ID:P50CA221703-01
      Date: 2017 - 2022
      Title:Core 2: Melanoma Clinical Database, Tissue Resource and Translational Pathology Core (MelCore)
      Funding Source:NIH/NCI
      Role:Co-Director
      ID:P50CA221703-01
      Date: 2017 - 2019
      Title:Understanding and Improving Outcomes in Refractory Melanoma
      Funding Source:Adelson Medical Research Foundation
      Role:PI
      ID:01
      Date: 2017 - 2023
      Title:Rational Approaches to Melanoma Therapy
      Funding Source:NIH/NCI
      Role:Co-PI
      ID:5 U54CA224070-04
      Date: 2017 - 2022
      Title:Immune and metabolic parthenogenesis of melanoma brain metastasis
      Funding Source:NIH/NCI
      Role:PI
      ID:2R01CA154710-10
      Date: 2017 - 2020
      Title:PKC as Node to Overcome Intrinsic MEK Inhibitor Resistance in Melanoma
      Funding Source:Melanoma Research Alliance
      Role:Co-I
      ID:508743
      Date: 2017 - 2022
      Title:Combining targeted therapy and immunotherapy in advanced melanoma
      Funding Source:NIH/NCI
      Role:Co-PI
      ID:1R01CA215122-01
      Date: 2016 - 2019
      Title:Targeting the Glycolysis Pathway to Overcome Resistance to Cancer Immunotherapy
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:Collaborator
      ID:RP170401
      Date: 2016 - 2017
      Title:Administrative Supplement to Study Mechanisms of Cancer Sensitivity and Resistance to Therapy Utilizing Samples and Information from Human Clinical Trials
      Funding Source:NIH/NCI
      Role:Co-Project Leader
      ID:P30CA016672
      Date: 2016 - 2019
      Title:Understanding the Immune-biology of Checkpoint Inhibitors to Develop New Strategies for Therapy
      Funding Source:DOD Translational Team Science Award
      Role:Co-I
      ID:CA 150619P2
      Date: 2016 - 2021
      Title:Strategies to improve immunotherapy for melanoma brain metastases
      Funding Source:NIH/NCI
      Role:Co-I
      ID:R01
      Date: 2016 - 2018
      Title:Molecular basis of therapeutic resistance and brain metastasis in melanoma
      Funding Source:SINF
      Role:PI
      Date: 2016 - 2019
      Title:Understanding the Immune-Biology of Checkpoint Inhibitors to Develop New Strategies for Therapy
      Funding Source:Melanoma Research Alliance
      Role:Co-I
      ID:Team Science Grant
      Date: 2016 - 2019
      Title:Exploiting Molecular and Metabolic Dependencies to Optimize Personalized Therapeutic Approaches for Melanomas
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:PI
      ID:RP160183
      Date: 2016 - 2019
      Title:Targeting the PI3K/Akt pathway to improve immunotherapy for melanoma brain metastases
      Funding Source:DoD Translational Team Science Award
      Role:Collaborator
      ID:CA12345
      Date: 2016 - 2019
      Title:Characterizing unusual responders to optimize the use of targeted therapies for BRAF-mutant metastatic melanoma
      Funding Source:DoD Translational Team Science Award
      Role:PI
      ID:CA150628
      Date: 2015 - 2022
      Title:Promoting a Bim-driven Apoptosis through MAPK Inhibition" A Therapeutic Strategy in Advanced Melanoma
      Funding Source:NIH/NCI
      Role:Co-I
      ID:1R01CA193970-05
      Date: 2015 - 2020
      Title:Bayesian approaches for heterogeneous molecular networks in cancer
      Funding Source:NIH/NCI
      Role:Co-I
      Date: 2015 - 2019
      Title:Phase II Open Label Two Arm Study of the MEK Inhibitor Trametinib to investigate the Safety and Anti-Cancer Activity in subjects with Melanoma with BRAF non-V600 Mutations
      Funding Source:National Comprehensive Cancer Network
      Role:PI
      ID:13835
      Date: 2014 - 2019
      Title:Identifying rational therapeutic approaches for "Wild Type" Melanoma
      Funding Source:Melanoma Research Foundation
      Role:PI
      ID:01
      Date: 2014 - 2015
      Title:Rational New Therapeutic Approaches to Overcome Resistance in Melanoma
      Funding Source:Adelson Medical Research Foundation
      Role:PI
      Date: 2014 - 2017
      Title:In Vitro and In Vivo Effects of SAR260301 on the Anti-Tumor Immune Response
      Funding Source:Sanofi S.A
      Role:PI
      ID:38876
      Date: 2014 - 2018
      Title:BRF117277, A Phase II, Open-Label, Multicenter Study of Dabrafenib plus Trametinib
      Funding Source:GlaxoSmithKline
      Role:PI
      ID:BRF117277
      Date: 2014 - 2020
      Title:The Role of the PI3K Pathway in Immune Resistance
      Funding Source:NIH/NCI
      Role:PI
      ID:1R01CA187076-05
      Date: 2014 - 2019
      Title:Clinical significance and targeting of oxidative phosphorylation in melanoma
      Funding Source:NIH/NCI
      Role:PI
      ID:GRANT11497965
      Date: 2014 - 2018
      Title:A High-Throughput Model for Human Melanoma
      Funding Source:NIH/NCI
      Role:Collaborator
      ID:2R01CA121118-06A1
      Date: 2014 - 2016
      Title:A High-Throughput Model for Human Melanoma
      Funding Source:NIH/NCI
      Role:Collaborator
      ID:2R01CA121118-06A1
      Date: 2014 - 2015
      Title:A High-Throughput Model for Human Melanoma
      Funding Source:University of Utah
      Role:PI
      ID:3-R01-CA121118-06A1
      Date: 2014 - 2019
      Title:An Open-Label, Multicenter, Corollary Study of Pre-Operative Therapy with Dabrafenib
      Funding Source:GSK Biologicals
      Role:PI
      ID:BRV116521
      Date: 2013 - 2014
      Title:BRAF inhibitor Debrafenib +/- MEK inhibitor Trametinib in combination with ipilimumab for V600E/K Mutation Positive Metastatic or Unresectable Melanoma
      Funding Source:GSK Biologicals
      Role:PI
      Date: 2013 - 2021
      Title:Strategies to improve immunotherapy for melanoma brain metastases
      Funding Source:NIH/NCI
      Role:Collaborator
      Date: 2013 - 2014
      Title:BRAF-Mediated Senescence, in Lung Cancer
      Funding Source:American Lung Association
      Role:Co-I
      Date: 2013 - 2019
      Title:Targeting BRAF-mutant melanoma brain metastases
      Funding Source:Melanoma Research Alliance
      Role:PI
      ID:01
      Date: 2013 - 2016
      Title:Evaluation of the Immune Response in Tumor biopsies from Melanoma Patients Treated with Dabrafenib (GXK2118436) +/- Trametinib (GSK1120212) in Combination with Ipilimumab
      Funding Source:GlaxoSmithKline
      Role:PI
      Date: 2013 - 2015
      Title:Optimizing Patient Selection and Overcoming Resistance for Therapies for Advanced Melanoma
      Funding Source:Adelson Medical Research Foundation
      Role:PI
      ID:01
      Date: 2012 - 2015
      Title:Patterns and Outcomes of Treatment Sequencing in Metastatic Melanoma
      Funding Source:Genentech
      Role:PI
      ID:C4-159443
      Date: 2012 - 2015
      Title:Signaling Pathways and Therapeutic Targets in 'wild-type' Melanoma
      Funding Source:Melanoma Research Alliance
      Role:Co-I
      Date: 2012 - 2013
      Title:PTEN Immunohistochemistry in patients treated with PX-866
      Funding Source:Oncothyreon Inc
      Role:Co-I
      ID:LS2012-00036478LK
      Date: 2011 - 2015
      Title:Clinical and molecular characterization of combined BRAF and MEK inhibitor treatment in patients with metastatic melanoma resistant to BRAF inhibitor alone
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:PI
      ID:RP120505
      Date: 2011 - 2014
      Title:BRAF-meditated senescence, apoptosis, and synthetic lethality in lung cancer
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:Collaborator
      Date: 2011 - 2014
      Title:TOR kinase inhibitors for leukemia therapy: mechanisms of action and resistance
      Funding Source:University of California-Irvine
      Role:Collaborator
      ID:1 R01 CA158383 01 A1
      Date: 2011 - 2012
      Title:MD Anderson Melanoma Spore Career Development Award
      Funding Source:NIH/NCI
      Role:PI
      Date: 2011 - 2015
      Title:Team Science: Clinicopathologic and Molecular Staging & Prognosis in Early-Stage Melanoma
      Funding Source:Melanoma Research Alliance
      Role:Co-PI
      Date: 2011 - 2012
      Title:Reverse phase protein array analysis of RG7204-sensitive and resistant melanoma xenografts
      Funding Source:Hoffman La Roche Inc
      Role:PI
      Date: 2011 - 2012
      Title:Determinants of melanocyte viability
      Funding Source:NYU Medical Center
      Role:Collaborator
      Date: 2011 - 2012
      Title:Targeted inhibition of inducible nitric oxide synthase as therapy for oral cancer
      Funding Source:Mt. Sinai School of Medicine
      Role:Collaborator
      Date: 2011 - 2012
      Title:Differential melanocyte response in occupational vitiligo and contact leukoderma
      Funding Source:NYU Medical Center
      Role:Collaborator
      Date: 2011 - 2016
      Title:The Role of the PI3K-AKT Pathway in Melanoma Brain Metastases
      Funding Source:NIH/NCI
      Role:PI
      ID:5R01CA154710-04
      Date: 2010 - 2015
      Title:Using the MHC class 1 cytoplasmic tail to control tumor Ag presentation by DCs
      Funding Source:NIH/NCI
      Role:Collaborator
      Date: 2010 - 2013
      Title:Augmenting T-Cell Based Melanoma Immunotherapy by Targeting Oncogenic BRAF
      Funding Source:Cancer Prevention & Research Institute of Texas (CPRIT)
      Role:Co-I
      Date: 2010 - 2013
      Title:BRF113929: A Phase II Open-label, two-cohort, multicenter study of GSK2118436 as a single agent in treatment naive and previously treated subjects with BRAF mutation-positive metastatic melanoma to the brain
      Funding Source:GlaxoSmithKline
      Role:PI
      ID:CS2011-00034767MA
      Date: 2010 - 2011
      Title:Assessment of P13K pathway activation in routinely available tumor samples for clinical implementation
      Funding Source:Institute for Personalized Cancer Therapy
      Role:Co-PI
      ID:01
      Date: 2010 - 2015
      Title:UT MD Anderson Cancer Center SPORE in Melanoma (PC-B)
      Funding Source:NIH/NCI
      Role:Core Co-Leader
      ID:5 P50 CA093459-10
      Date: 2010 - 2012
      Title:Comparative Effects of MK-2206 and AKT1/2i in Human Melanoma Cell Lines
      Funding Source:Merck and Co., Inc
      Role:PI
      ID:LS2010-00032311LG
      Date: 2010 - 2011
      Title:Effects of AZD6244 and AZD8055 on the Growth, Survival, and Metabolism of Melanoma
      Funding Source:AstraZeneca
      Role:PI
      ID:LS2010-00026790DH
      Date: 2010 - 2015
      Title:The Development of Rational Approaches for Brain Metastases
      Funding Source:NIH/NCI
      Role:PI
      ID:1DP2OD007187-01
      Date: 2010 - 2011
      Title:Molecular targeting of the oncogene eIF4E in melanoma
      Funding Source:Harry J. Lloyd
      Role:Collaborator
      Date: 2010 - 2011
      Title:Determination of PTEN expression in melanoma clinical specimens
      Funding Source:Myriad Genetics Inc
      Role:PI
      ID:LS2010-00032645JW
      Date: 2010 - 2013
      Title:Enhancing the efficacy of targeted therapies in the treatment of melanoma
      Funding Source:NYU Medical Center
      Role:Collaborator
      Date: 2010 - 2012
      Title:Identification and Characterization of Optimal Combinatorial Targeted Therapy Approaches for Melanoma
      Funding Source:GlaxoSmithKline
      Role:PI
      ID:LS2010-00033057JW
      Date: 2010 - 2013
      Title:Role of the PI3K-AKT Pathway in Resistance to BRAF Inhibition in Melanoma
      Funding Source:American Society of Clinical Oncologists - Career Development Award
      Role:PI
      ID:01
      Date: 2010 - 2013
      Title:The Role of the PI3K-AKT Pathway in Melanoma Brain Metastasis
      Funding Source:Damon Runyon
      Role:PI
      Date: 2010 - 2013
      Title:Novel signaling pathways and therapeutic targets in 'wild-type' melanoma
      Funding Source:MRA
      Role:Collaborator
      Date: 2010 - 2012
      Title:Identifying Therapeutic Targets for Melanoma Brain Metastases
      Funding Source:Melanoma Research Alliance - Young Investigator
      Role:PI
      Date: 2010 - 2011
      Title:BRAF Mutations in Metastatic Colorectal Cancer
      Funding Source:G.S. Hogan Gastrointestinal Cancer Research Fund
      Role:Collaborator
      Date: 2010 - 2010
      Title:Prognostic Significance of BRAF Mutations in Immunologic Treatment of Melanoma
      Funding Source:CCTS
      Role:PI
      Date: 2009 - 2012
      Title:The Development of Rational Therapeutic Approaches for Melanoma Brain Metastases
      Funding Source:University of Texas MD Anderson Cancer Center - Physician Scientist Program
      Role:PI
      ID:01
      Date: 2009 - 2011
      Title:Identifying DNA repair/replication defects in cancer by classifiers of genomic progression
      Funding Source:NIH/NCI
      Role:Collaborator
      Date: 2009 - 2010
      Title:Evaluating the Effects of BRAF Mutations on the Suppression of the Immune Response to Melanoma
      Funding Source:MRF
      Role:Collaborator
      Date: 2008 - 2017
      Title:A Phase 1/1b study for the evaluation of SAR260301, administered orally in monotherapy in patients with advanced solid tumors or lymphomas, and in combination with vemurafenib in patients with unresectable/metastatic BRAF mutated melanoma
      Funding Source:Sanofi S.A
      Role:PI
      ID:SAR260301
      Date: 2008 - 2011
      Title:ASCO Career Development Award
      Funding Source:ASCO
      Role:PI
      Date: 2008 - 2011
      Title:Physician-Scientist
      Funding Source:University of Texas MD Anderson Cancer Center
      Role:PI
      Date: 2008 - 2010
      Title:Optimization of Patient Selection & Combinatorial Approaches with PLX4720
      Funding Source:University of Texas MD Anderson Cancer Center
      Role:PI
      ID:01
      Date: 2008 - 2010
      Title:The Role of Activating Mutations of the P13K Pathway in Melanoma
      Funding Source:University of Texas MD Anderson Cancer Center
      Role:PI
      ID:01
      Date: 2007 - 2009
      Title:Overcoming Taxol Resistance in Metastatic Melanoma
      Funding Source:John S. Dunn Gulf Coast Consortium
      Role:PI
      ID:01
      Date: 2007 - 2008
      Title:Identification of Targeted therapy Strategies to Overcome Paclitaxel Resistance in Metastatic Melanoma
      Funding Source:University of Texas MD Anderson SPORE in Melanoma
      Role:PI
      ID:01
      Date: 2007 - 2009
      Title:Overcome Paclitaxel Resistance in Metastatic Melanoma
      Funding Source:University of Texas MD Anderson Cancer Center
      Role:Developmental Project Leader
      ID:5 P50 CA093459 04 PP-DRP3
      Date: 2007 - 2008
      Title:Kit Mutation in Acral Lentiginous & Mucosal Melanoma
      Funding Source:University of Texas MD Anderson Cancer Center
      Role:Collaborator
      ID:5 P50 CA093459 04 PP-DRP18
      Date: 2007 - 2010
      Title:Optimization of patient selection and combinatorial targets with AZD6244 for Metastatic Melanoma
      Funding Source:AstraZeneca
      Role:PI
      ID:LS2006-00016301 (PP-08)
      Date: 2005 - 2007
      Title:Characterization of Protein Signaling Pathways and Gene Expression in Human Melanoma Brain Metastases
      Funding Source:University of Texas MD Anderson Cancer Center
      Role:Co-PI
      ID:5 P50 CA093459 03 PP-DRP3
      Date: 2005 - 2008
      Title:Effects of Combined Therapy with BAY43-9006 and CCI-779 on Protein Signaling Networks and Correlation with Clinical Outcomes in Malignant Melanoma
      Funding Source:American Society of Clinical Oncology
      Role:PI
      ID:01
      Date: 2001 - 2020
      Title:The University of Texas MD Anderson Cancer Center SPORE in Melanoma
      Funding Source:NIH/NCI
      Role:Core Co-Leader
      ID:2P50CA093459-11
      Title:The Contribution of the Microenvironment to the Chemoresistance of Melanoma Brain Metastasis
      Funding Source:MRF
      Role:Collaborator
      Title:Developing Dasatinib and Associated Predictive Biomarkers for Treating Melanoma
      Funding Source:NIH
      Role:Collaborator
      Title:Therapeutic Potential of Targeting GPER in Cancer
      Funding Source:NIH/NCI
      Role:Co-I
      Title:Metabolic pathogenesis of melanoma brain metastases
      Funding Source:NIH/NCI
      Role:PI
      Title:Clinical and Therapeutic Significance of G Protein-Coupled Estrogen Receptor Signaling in Melanoma
      Funding Source:Melanoma Research Alliance
      Role:Co-PI

      Selected Publications

      Peer-Reviewed Articles

      1. Vashisht Gopal, YN, de Groot, EL, Loftin, K, Knighton, B, Ledesma, D, Hudgens, CW, Shamsutdinova, D, Ali, M, Ju, Z, Xiao, M, Kannan, T, Fontenot, G, Nakazawa, MS, Thomas, M, Wani, K, Stephan, C, Aung, PP, Kwong, L, Roszik, J, Akbani, R, Kossenkov, AV, Rebecca, VW, Sullivan, RJ, Herlyn, M, Davies, MA. Personalized targeting of BCL2 family proteins overcomes acquired resistance to BRAF-MEK inhibitors in preclinical melanoma. Nature communications 17(1), 2026. e-Pub 2026. PMID: 42362544.
      2. Tlali MR, Kassanjee R, van den Heuvel LL, Rabie S, Joska J, Orrell C, Seedat S, Prozesky H, Adorjan K, Davies MA, Johnson LF, Haas AD. Suicidal thoughts and behaviours in Cape Town: A cross-sectional study of prevalence and social, contextual, and clinical correlates. SSM Ment Health 10, 2026. e-Pub 2026. PMID: 42559485.
      3. Nader NE, Glathar AR, Byrnes EV, Joy M, Ge T, Elliott A, Jaehne R, Layding CJ, Tatsuoka CM, Sica G, Acharya R, Bao R, Cillo AR, Joon AY, Kumar S, Yanes RB, Wu X, Solis Soto LM, Arrechedera CA, Tamegnon A, Sanchez-Espiridion B, Tawbi HA, Burton EM, Davies MA, Pearce TM, Burns TF, Stabile LP, Zhang X, Bruno TC. Functionally active lymphoid aggregates correlate with improved prognosis in brain metastases. Cancer Discov, 2026. e-Pub 2026. PMID: 42684018.
      4. Nyakato P, Euvrard J, Chinogurei C, Boulle A, Heyden EV, Davies MA. HIV care interruptions during the first year of antiretroviral therapy among adolescents and young adults living with HIV aged 15-24 years in Khayelitsha, South Africa. J Acquir Immune Defic Syndr, 2026. e-Pub 2026. PMID: 42562379.
      5. Herb J, Bassett RL, Torres-Cabala CA, Prieto VG, Patel SP, Holder AM, Fisher SB, Lucci A, Wargo J, Amaria RN, Davies MA, Glitza Oliva IC, Tawbi HA, McQuade J, Ikeguchi AP, Wong MK, Diab AK, Gershenwald JE, Ross MI, Weiser R. Real-World Outcomes for Patients with Clinically Node-Positive Melanoma Undergoing Neoadjuvant Immunotherapy and Nodal Dissection. Ann Surg Oncol 33(7):6700-6708, 2026. e-Pub 2026. PMID: 41838361.
      6. Whitesell Skrivankova V, Pelteret R, Rabie S, Tlali M, Folb N, Rohner E, Chinogurei C, Ruffieux Y, Seedat S, Davies MA, Maartens G, Joska J, Haas AD. Risk of unnatural death following self-harm in South Africa: development and validation of multivariable prognostic models. BMJ Ment Health 29(1), 2026. e-Pub 2026. PMID: 42350059.
      7. Tsingas K, Thomas M, Reale M, Xiao M, Wickramasinghe J, Chen Y, Duong B, Lucas A, Thacker G, Li H, Mou H, Ramirez-Salazar E, Elbasir A, Villanueva J, Xu X, Flowers A, Karakousis GC, Miura JT, Mitchell TC, Amaravadi RK, Schuchter LM, Liu S, Long Q, Hoon DSB, Ramos RI, Catbagan JJ, Bustos MA, Gershenwald JE, Simon JM, Wargo JA, Davies MA, Lu Y, Mills GB, Cohen S, Lawless A, Sharova T, Frederick DT, Flaherty KT, Hacohen N, Boland GM, Auslander N, Herlyn M. Melanoma-patient-derived xenograft multi-omics resource melPDomiX maps gain- and loss-of-function alterations. Cell Rep 45(6):117455, 2026. e-Pub 2026. PMID: 42234561.
      8. Hunter M, Hannan L, Boulle A, Matjila M, Ismail M, Euvrard J, Davies MA, Kalk E. The impact of the COVID-19 pandemic on maternal mortality in a South African metropole (2020 - 2021): A retrospective cohort study. S Afr Med J 116(5):e3856, 2026. e-Pub 2026. PMID: 42246854.
      9. Ali, MM, Alauddin, M, Mahmud, I, Joon, A, Momin, AB, Cortez, JR, Chen, H, Tan, L, Chan, W, Anantha, RW, Stolley, D, Shamsutdinova, D, Evans, KW, Merric-Bernstam, F, Herlyn, M, Thomas, M, Chen, Y, Davies, MA, Chattopadhyay, C. The Imipridone ONC206 Inhibits Tumor Growth and Improves Survival in Patient-Derived Xenograft Models of Uveal Melanoma. Cancers 18(12), 2026. e-Pub 2026. PMID: 42352430.
      10. Wang J, Wee Y, Jacob T, Rogers A, Sorensen LK, Brooks DM, Gupta P, Tay JKH, Wilson EC, Liu T, Smith EA, Gopal YNV, Davies MA, McMahon M, Holmen SL, Judson-Torres RL, Wolff RK, Grossmann AH. Rapid activation of ARF6 after RAF inhibition augments BRAF(V600E) and promotes therapy resistance. Oncogene 45(23):2286-2298, 2026. e-Pub 2026. PMID: 42050077.
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      64. Hasanov, M, Kiany, S, Forget, MA, Bassett Jr, R, Davies, MA, Diab, A, Gershenwald, JE, Glitza, IC, Lee, JE, Lucci, A, McQuade, JL, Patel, SP, Ross, MI, Tawbi, H, Wargo, J, Wong, MK, Bernatchez, C, Hwu, P, Haymaker, CL, Amaria, RN. Lymphodepletion, tumor-infiltrating lymphocytes, and high versus low dose IL-2 followed by pembrolizumab in patients with metastatic melanoma. OncoImmunology 14(1), 2025. e-Pub 2025. PMID: 40815607.
      65. Eliason, J, Krishnan, S, Fukuda, Y, Bustos, M, Winkowski, D, Cho, SN, Basi, A, Baird, R, Grimm, EA, Davies, MA, Hoon, DS, Uppore Kukkillaya, AR, Burks, JK, Ekmekcioglu, S. Characterizing spatial immune architecture in metastatic melanoma using high-dimensional multiplex imaging. Frontiers in immunology 16, 2025. e-Pub 2025. PMID: 40364843.
      66. Tiago, M, Purwin, TJ, Stefanski, CD, da Silva, RO, Fane, M, Chhabra, Y, Haj, JI, Teh, JL, Kadamb, R, Cai, W, Rosenbaum, S, Chua, V, Hacohen, N, Davies, MA, Villanueva, J, Chervoneva, I, Weeraratna, AT, Erkes, DA, Capparelli, C, Aguirre-Ghiso, JA, Aplin, AE. Elevated NR2F1 underlies the persistence of invasive disease after treatment of BRAF-mutant melanoma. Journal of Clinical Investigation 135(15), 2025. e-Pub 2025. PMID: 40955663.
      67. Jacob N, Kalk E, Heekes A, Phelanyane F, Anderson K, Davies MA, Rice B, Boulle A. The impact of evolving maternal antiretroviral therapy guidelines on vertical transmission of HIV in the Western Cape, South Africa. PLoS One 20(9):e0328612, 2025. e-Pub 2025. PMID: 40934266.
      68. Claus LM, Kostan HE, Hicks ME, Avritscher R, Davies MA. Case Report: Durable remission after abscopal effect following transcatheter hepatic arterial embolization in a patient with mucosal melanoma refractory to immunotherapy. Front Immunol 16:1565355, 2025. e-Pub 2025. PMID: 40276508.
      69. Phillips TK, Gomba Y, Mogoba P, Phelanyane F, Anderson K, Chi BH, Clouse K, Davies MA, Euvrard J, Knight L, Myer L, Abrams EJ. Routine Electronic Mother-Infant Data (REMInD): a proof-of-concept Data to Care study to support retention in maternal HIV treatment and infant HIV testing in Cape Town, South Africa. Res Sq, 2024. e-Pub 2024. PMID: 39711541.
      70. Wee, Y, Wang, J, Wilson, EC, Rich, CP, Rogers, A, Tong, ZZ, DeGroot, E, Yennu Nanda, VG, Davies, MA, Ekiz, HA, Tay, JK, Stubben, C, Boucher, K, Oviedo, JM, Fairfax, KC, Williams, MA, Holmen, SL, Wolff, RK, Grossmann, AH. Tumour-intrinsic endomembrane trafficking by ARF6 shapes an immunosuppressive microenvironment that drives melanomagenesis and response to checkpoint blockade therapy. Nature communications 15(1), 2024. e-Pub 2024. PMID: 39098861.
      71. Brenner IR, Flanagan CF, Penazzato M, Webb KA, Horsfall SB, Hyle EP, Abrams E, Bacha J, Neilan AM, Collins IJ, Desmonde S, Crichton S, Davies MA, Freedberg KA, Ciaranello AL. Cost-effectiveness of viral load testing for transitioning antiretroviral therapy-experienced children to dolutegravir in South Africa: a modelling analysis. Lancet Glob Health 12(12):e2068-e2079, 2024. e-Pub 2024. PMID: 39577977.
      72. de Beer ST, Davies MA, Phelanyane F, Jones HE, Ingle SM, Eley BS, Anderson K, Heekes A, Kalk E, Mendelsohn A, Boulle A, Slogrove AL. The Retrospective Implementation of Standardized In Utero HIV Exposure Definitions Using Routinely Collected Public Sector Data Across the Western Cape Province, South Africa. Pediatr Infect Dis J 43(11):1061-1064, 2024. e-Pub 2024. PMID: 39079034.
      73. Rumke LW, Davies MA, Vestjens SMT, van der Putten BCL, Bril-Keijzers WCM, van Houten MA, Rots NY, Wijmenga-Monsuur AJ, van der Ende A, de Gier B, Vlaminckx BJM, van Sorge NM. Nationwide upsurge in invasive disease in the context of longitudinal surveillance of carriage and invasive Streptococcus pyogenes 2009-2023, the Netherlands: a molecular epidemiological study. J Clin Microbiol 62(10):e0076624, 2024. e-Pub 2024. PMID: 39194268.
      74. Chattopadhyay C, Roszik J, Bhattacharya R, Alauddin M, Mahmud I, Yadugiri S, Ali MM, Khan FS, Prabhu VV, Lorenzi PL, Wei B, Burton E, Morey RR, Lazcano R, Davies MA, Patel SP, Grimm EA. Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma. Br J Cancer 131(11):1846-1857, 2024. e-Pub 2024. PMID: 39394450.
      75. Li, J, Liu, W, Mojumdar, K, Kim, H, Zhou, Z, Ju, Z, Kumar, SV, Ng, PS, Chen, H, Davies, MA, Lu, Y, Akbani, R, Mills, GB, Liang, H. A protein expression atlas on tissue samples and cell lines from cancer patients provides insights into tumor heterogeneity and dependencies. Nature Cancer 5(10):1579-1595, 2024. e-Pub 2024. PMID: 39227745.
      76. Anderson K, van Zyl G, Hsiao NY, Claassen M, Mudaly V, Voget J, Heekes A, Kalk E, Phelanyane F, Boulle A, Sridhar G, Ragone L, Vannappagari V, Davies MA. HIV Drug Resistance in Newly Diagnosed Young Children in the Western Cape, South Africa. Pediatr Infect Dis J 43(10):970-976, 2024. e-Pub 2024. PMID: 39079031.
      77. Bauer IE, Davies MA, Bona KA, Hararuk O, Shaw CH, Thompson DK, Kurz WA, Webster KL, Garneau M, McLaughlin JW, Packalen MS, Prystupa E, Sanderson NK, Tarnocai C. Peat profile database from peatlands in Canada. Ecology 105(10):e4398, 2024. e-Pub 2024. PMID: 39143756.
      78. Shafi J, Virk MK, Kalk E, Carlucci JG, Chepkemoi A, Bernard C, McHenry MS, Were E, Humphrey J, Davies MA, Mehta UC, Patel RC. Pharmacovigilance in Pregnancy Studies, Exposures and Outcomes Ascertainment, and Findings from Low- and Middle-Income Countries: A Scoping Review. Drug Saf 47(10):957-990, 2024. e-Pub 2024. PMID: 38907172.
      79. Schultz, DF, Davies, BA, Payne, JA, Martin, CP, Minard, AY, Childs, BG, Zhang, C, Jeganathan, K, Sturmlechner, I, White, TA, de Bruin, A, Harkema, L, Chen, H, Davies, MA, Jachim, S, LeBrasseur, NK, Piper, RC, Li, H, Baker, DJ, van Deursen, JM, Billadeau, DD, Katzmann, DJ. Loss of HD-PTP function results in lipodystrophy, defective cellular signaling and altered lipid homeostasis. Journal of cell science 137(18), 2024. e-Pub 2024. PMID: 39155850.
      80. Ruffieux Y, Folb N, Grimsrud A, Hislop M, Dunn L, Rohner E, Namubiru AM, Chinogurei C, Cornell M, Davies MA, Egger M, Maartens G, Haas AD. Courier delivery of antiretroviral therapy: a cohort study of a South African private-sector HIV programme. J Int AIDS Soc 27(9):e26360, 2024. e-Pub 2024. PMID: 39295119.
      81. Saberian, C, Milton, D, Simon, JM, Amaria, RN, Diab, A, McQuade, JL, Patel, SP, Tawbi, H, Yee, C, Wong, MK, McCutcheon, IE, Davies, MA, Ferguson, SD, Glitza, IC. Survival and treatment outcomes in patients with leptomeningeal disease from metastatic melanoma. Neuro-Oncology Practice 11(4):452-463, 2024. e-Pub 2024. PMID: 39006528.
      82. Gellert, J, Agardy, DA, Kumar, S, Kourtesakis, A, Boschert, T, Jähne, K, Breckwoldt, MO, Bunse, L, Wick, W, Davies, MA, Platten, M, Bunse, T. Tumoral Interferon Beta Induces an Immune-Stimulatory Phenotype in Tumor-Associated Macrophages in Melanoma Brain Metastases. Cancer Research Communications 4(8):2189-2202, 2024. e-Pub 2024. PMID: 39056192.
      83. Nyakato P, Schomaker M, Boulle A, Euvrard J, Wood R, Eley B, Prozesky H, Christ B, Anderegg N, Ayakaka I, Rafael I, Kunzekwenyika C, Moore CB, van Lettow M, Chimbetete C, Mbewe S, Ballif M, Egger M, Yiannoutsos CT, Cornell M, Davies MA. Correcting mortality estimates among children and youth on antiretroviral therapy in southern Africa: A comparative analysis between a multi-country tracing study and linkage to a health information exchange. Trop Med Int Health 29(8):739-751, 2024. e-Pub 2024. PMID: 38961819.
      84. Kalk E, Heekes A, Lavies D, Jacobs L, Spencer C, Boutall A, Osman A, Stewart C, Davies MA, van Niekerk A, Fieggen K, Boulle A, Mehta U. Population-based prevalence of congenital defects in a routine sentinel site-based surveillance system in the Western Cape, South Africa. Birth Defects Res 116(8):e2388, 2024. e-Pub 2024. PMID: 39118354.
      85. Smith P, Little F, Hermans S, Davies MA, Wood R, Orrell C, Pike C, Peters F, Dube A, Georgeu-Pepper D, Curran R, Fairall L, Bekker LG. A prospective randomised controlled trial investigating household SARS-CoV-2 transmission in a densely populated community in Cape Town, South Africa - the transmission of COVID-19 in crowded environments (TRACE) study. BMC Public Health 24(1):1924, 2024. e-Pub 2024. PMID: 39020307.
      86. Moolla H, Davies MA, Davies C, Euvrard J, Prozesky HW, Fox MP, Orrell C, Von Groote P, Johnson LF. The effect of care interruptions on mortality in adults resuming antiretroviral therapy. AIDS 38(8):1198-1205, 2024. e-Pub 2024. PMID: 38814712.
      87. White, BS, Woo, XY, Koc, S, Sheridan, T, Neuhauser, S, Wang, S, Evrard, YA, Chen, L, Pour, AF, Landua, J, Mashl, RJ, Davies, S, Fang, B, Rosa, MG, Evans, KW, Bailey, MH, Chen, Y, Xiao, M, Rubinstein, JC, Sanderson, BJ, Lloyd, M, Domanskyi, S, Dobrolecki, LE, Fujita, M, Fujimoto, J, Xiao, G, Fields, RC, Mudd, JL, Xu, X, Hollingshead, MG, Jiwani, S, Acevedo, S, Davis-Dusenbery, BN, Robinson, PN, Moscow, JA, Doroshow, JH, Mitsiades, N, Kaochar, S, Pan, CX, Carvajal-Carmona, L, Welm, AL, Welm, BE, Govindan, R, Li, S, Davies, MA, Roth, JA, Meric-Bernstam, F, Xie, Y, Herlyn, M, Ding, L, Chuang, JH. A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis. Cancer Research 84(13):2060-2072, 2024. e-Pub 2024. PMID: 39082680.
      88. Ledesma DA, Marques-Piubelli ML, Li-Ning-Tapia E, Hudgens C, Gu J, Lazcano R, Casavilca-Zambrano S, Castillo M, Davies MA, Hwu WJ, Aung PP, Giubellino A, Curry JL, Torres-Cabala C. Apoptosis Pathway-Associated Proteins Are Frequently Expressed in Melanoma: A Study of 32 Cases With Focus on Acral Lentiginous Melanoma. Am J Dermatopathol 46(7):410-415, 2024. e-Pub 2024. PMID: 38718197.
      89. Meric-Bernstam F, Lloyd MW, Koc S, Evrard YA, McShane LM, Lewis MT, Evans KW, Li D, Rubinstein LV, Welm AL, Dean DA, Srivastava A, Grover JW, Ha MJ, Chen H, Huang X, Varadarajan K, Wang J, Roth JA, Welm BE, Govindan R, Ding L, Kaochar S, Mitsiades N, Carvajal-Carmona LG, Herlyn M, Davies MA, Shapiro GI, Fields RC, Trevino JG, Harrell JC, Doroshow JH, Chuang JH, Moscow JA. Assessment of Patient-Derived Xenograft Growth and Antitumor Activity: The NCI PDXNet Consensus Recommendations. Mol Cancer Ther 23(7):924-938, 2024. e-Pub 2024. PMID: 38641411.
      90. Jacobs T, Morden E, Smith M, von Delft A, Kassanjee R, Mudaly V, Boulle A, Davies MA. Severe outcomes among adults with TB during COVID-19. IJTLD Open 1(7):292-298, 2024. e-Pub 2024. PMID: 39035425.
      91. Sohn AH, Davies MA. Adults with perinatally acquired HIV in low- and middle-income settings: time for a generational shift in HIV care and global guidance. J Int AIDS Soc 27(7):e26338, 2024. e-Pub 2024. PMID: 39034739.
      92. Chua V, Lopez-Anton M, Terai M, Tanaka R, Baqai U, Purwin TJ, Haj JI, Waltrich Jr FJ, Trachtenberg I, Luo K, Tudi R, Jeon A, Han A, Chervoneva I, Davies MA, Aguirre-Ghiso JA, Sato T, Aplin AE. Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress. PubMed 17(840), 2024. e-Pub 2024. PMID: 38861613.
      93. Kassanjee R, Davies MA, Heekes A, Mahomed H, Hawkridge AJ, Morden E, Jacobs T, Cohen C, Moultrie H, Lessells RJ, Van Der Walt N, Arendse JO, Wolter N, Walaza S, Jassat W, von Gottberg A, Hannan PL, Feikin DR, Cloete K, Boulle A. COVID-19 Vaccine Uptake and Effectiveness by Time since Vaccination in the Western Cape Province, South Africa: An Observational Cohort Study during 2020-2022. Vaccines (Basel) 12(6), 2024. e-Pub 2024. PMID: 38932357.
      94. Nyakato P, Boulle A, Wood R, Eley B, Rabie H, Egger M, Yiannoutsos CT, Davies MA, Cornell M. Self-transfers, Hospital Admissions and Mortality Among Children and Adolescents Lost to Follow-up From Antiretroviral Therapy Programs in the Western Cape, South Africa Between 2004 and 2019: Linkage to Provincial Records. Pediatr Infect Dis J 43(5):430-436, 2024. e-Pub 2024. PMID: 38451913.
      95. Phillips TK, Kassanjee R, Maxwell N, Anderson K, Johnson L, Moolla H, Myer L, Chi BH, Euvrard J, Boulle A, Davies MA, Cornell M, de Waal R. ART history prior to conception: trends and association with postpartum disengagement from HIV care in Khayelitsha, South Africa (2013-2019): a retrospective cohort study. J Int AIDS Soc 27(4):e26236, 2024. e-Pub 2024. PMID: 38566482.
      96. Kehoe K, Morden E, Zinyakatira N, Heekes A, Jones HE, Walter SR, Jacobs T, Murray J, Buys H, Redaniel MT, Davies MA. Lower respiratory tract infection admissions and deaths among children under 5 years in public sector facilities in the Western Cape Province, South Africa, before and during the COVID-19 pandemic (2019 - 2021). S Afr Med J 114(3):e1560, 2024. e-Pub 2024. PMID: 38525574.
      97. Anderson K, Kalk E, Heekes A, Phelanyane F, Jacob N, Boulle A, Mehta U, Kassanjee R, Sridhar G, Ragone L, Vannappagari V, Davies MA. Factors associated with vertical transmission of HIV in the Western Cape, South Africa: a retrospective cohort analysis. J Int AIDS Soc 27(3):e26235, 2024. e-Pub 2024. PMID: 38528395.
      98. Kasem J, Davies MAM, Chainey S, Ronca F. Musculoskeletal complaints in English law enforcement officers: a cross-sectional study. Int J Occup Saf Ergon 30(1):84-89, 2024. e-Pub 2024. PMID: 37434478.
      99. Kassanjee R, Davies MA, Heekes A, Mahomed H, Hawkridge AJ, Wolmarans M, Morden E, Jacobs T, Cohen C, Moultrie H, Lessells RJ, Van Der Walt N, Arendse JO, Goeiman H, Mudaly V, Wolter N, Walaza S, Jassat W, von Gottberg A, Hannan PL, Rousseau P, Feikin D, Cloete K, Boulle A. COVID-19 vaccine uptake and effectiveness by time since vaccination in the Western Cape province, South Africa: An observational cohort study during 2020-2022. medRxiv, 2024. e-Pub 2024. PMID: 38343866.
      100. Chattopadhyay C, Roszik J, Bhattacharya R, Alauddin M, Mahmud I, Yadugiri S, Ali MM, Khan FS, Prabhu VV, Lorenzi P, Burton E, Morey RR, Lazcano R, Davies MA, Patel SP, Grimm EA. Imipridones inhibit tumor growth and improve survival in an orthotopic liver metastasis mouse model of human uveal melanoma. bioRxiv, 2024. e-Pub 2024. PMID: 38293232.
      101. Slogrove AL, Bovu A, de Beer S, Phelanyane F, Williams PL, Heekes A, Kalk E, Mehta U, Theron G, Abrams EJ, Cotton MF, Myer L, Davies MA, Boulle A. Maternal and birth outcomes in pregnant people with and without HIV in the Western Cape, South Africa. AIDS 38(1):59-67, 2024. e-Pub 2024. PMID: 37720974.
      102. Chihana M, Conan N, Ohler L, Huerga H, Wanjala S, Masiku C, Szumilin E, Ellman T, Etard JF, Maman D, Davies MA. Changes Over Time in the Proportion of Advanced HIV Disease in Two High HIV Prevalence Settings in Ndhiwa (Kenya) and Eshowe (South Africa). J Int Assoc Provid AIDS Care 23:23259582241260219, 2024. e-Pub 2024. PMID: 38881294.
      103. Hussey H, Vreede H, Davies MA, Heekes A, Kalk E, Hardie D, van Zyl G, Naidoo M, Morden E, Bam JL, Zinyakatira N, Centner CM, Maritz J, Opie J, Chapanduka Z, Mahomed H, Smith M, Cois A, Pienaar D, Redd AD, Preiser W, Wilkinson R, Boulle A, Hsiao NY. SARS-CoV-2 seroepidemiology in Cape Town, South Africa, and implications for future outbreaks in low-income communities. PLOS Glob Public Health 4(8):e0003554, 2024. e-Pub 2024. PMID: 39106267.
      104. Menzies AM, Long GV, Kohn A, Tawbi H, Weber J, Flaherty K, McArthur GA, Ascierto PA, Pfluger Y, Lewis K, Tsai KK, Hamid O, Prenen H, Fein L, Wang E, Guenzel C, Zhang F, Kleha JF, di Pietro A, Davies MA. POLARIS: A phase 2 trial of encorafenib plus binimetinib evaluating high-dose and standard-dose regimens in patients with BRAF V600-mutant melanoma with brain metastasis. Neurooncol Adv 6(1):vdae033, 2024. e-Pub 2024. PMID: 38725995.
      105. Tsondai PR, Davies MA, Singtoroj T, Maxwell N, Technau KG, Chokephaibulkit K, Lumbiganon P, Sohn AH. Creating a data collection and management platform to support measurement of adolescent HIV care transition processes within low- and middle-income countries: The GRADUATE project. PLOS Glob Public Health 4(8):e0002705, 2024. e-Pub 2024. PMID: 39102384.
      106. Skrivankova VW, Hossmann S, Cornell M, Ballif M, Dupont C, Huwa J, Seintaridis K, Kalua T, Wandeler G, Kassanjee R, Haas AD, Technau KG, Fenner L, Low N, Davies MA, Egger M. Authorship inequalities in global health research: the IeDEA Southern Africa collaboration. BMJ Glob Health 8(12), 2023. e-Pub 2023. PMID: 38103897.
      107. Baqai U, Kurimchak AM, Trachtenberg IV, Purwin TJ, Haj JI, Han A, Luo K, Pachon NF, Jeon A, Chua V, Davies MA, Gutkind JS, Benovic JL, Duncan JS, Aplin AE. Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma. J Biol Chem 299(12):105418, 2023. e-Pub 2023. PMID: 37923138.
      108. Turmel-Courchesne L, Davies MA, Guene-Nanchen M, Strack M, Rochefort L. Rewetting increases vegetation cover and net growing season carbon uptake under fen conditions after peat-extraction in Manitoba, Canada. Sci Rep 13(1):20588, 2023. e-Pub 2023. PMID: 37996571.
      109. Wee Y, Wang J, Wilson EC, Rich CP, Rogers A, Tong Z, DeGroot E, Gopal YNV, Davies MA, Ekiz HA, Tay JKH, Stubben C, Boucher KM, Oviedo JM, Fairfax KC, Williams MA, Holmen SL, Wolff RK, Grossmann AH. ARF6-dependent endocytic trafficking of the Interferon-gamma receptor drives adaptive immune resistance in cancer. bioRxiv, 2023. e-Pub 2023. PMID: 37873189.
      110. Witt RG, Cass SH, Tran T, Damania A, Nelson EE, Sirmans E, Burton EM, Chelvanambi M, Johnson S, Tawbi HA, Gershenwald JE, Davies MA, Spencer C, Mishra A, Wong MC, Ajami NJ, Peterson CB, Daniel CR, Wargo JA, McQuade JL, Nelson KC. Gut Microbiome in Patients With Early-Stage and Late-Stage Melanoma. JAMA Dermatol 159(10):1076-1084, 2023. e-Pub 2023. PMID: 37647056.
      111. de Beer ST, Slogrove AL, Eley B, Ingle SM, Jones HE, Phelanyane F, Anderson K, Kalk E, Boulle A, Davies MA. Change in HIV-related characteristics of children hospitalised with infectious diseases in Western Cape, South Africa, 2008-2021: a time trend analysis. J Int AIDS Soc 26 Suppl 4(Suppl 4):e26151, 2023. e-Pub 2023. PMID: 37909168.
      112. Chagani S, De Macedo MP, Carapeto F, Wang F, Marzese DM, Wani K, Haydu LE, Peng W, Ong GT, Warren SE, Beechem JM, Hoon DSB, Mills GB, Tetzlaff MT, Lazar AJ, Kwong LN, Davies MA. Multiplatform Analysis Of Intratumoral Pten Heterogeneity In Melanoma. J Invest Dermatol 143(9):1779-1787.e1, 2023. e-Pub 2023. PMID: 36871660.
      113. Portuallo ME, Lu DY, Alicea GM, Bolling J, Lee R, McQuade J, Warner AB, Davies M, Weeraratna A, Villanueva J, Rebecca VW. Diversity, equity, and inclusion in the melanoma research community. Pigment Cell Melanoma Res 36(5):441-447, 2023. e-Pub 2023. PMID: 37093838.
      114. Cass SH, Tobin JWD, Seo YD, Gener-Ricos G, Keung EZ, Burton EM, Davies MA, McQuade JL, Lazar AJ, Mason R, Millward M, Sandhu S, Khoo C, Warburton L, Guerra V, Haydon A, Dearden H, Menzies AM, Carlino MS, Smith JL, Mollee P, Burgess M, Mapp S, Keane C, Atkinson V, Parikh SA, Markovic SN, Ding W, Call TG, Hampel PJ, Long GV, Wargo JA, Ferrajoli A. Efficacy of Immune Checkpoint Inhibitors for the Treatment of Advanced Melanoma in Patients with Concomitant Chronic Lymphocytic Leukemia. Ann Oncol 34(9):796-805, 2023. e-Pub 2023. PMID: 37414216.
      115. Baruch, EN, Nagarajan, P, Gleber-Netto, FO, Rao, X, Xie, T, Akhter, S, Adewale, A, Shajedul, I, Mattson, BJ, Ferrarotto, R, Wong, MK, Davies, MA, Jindal, S, Basu, S, Harwood, C, Leigh, I, Ajami, NJ, Futreal, A, Castillo, M, Gunaratne, PH, Goepfert, RP, Khushalani, N, Wang, J, Watowich, SS, Calin, GA, Migden, MR, Vermeer, PD, D'Silva, NJ, Yaniv, D, Burks, JK, Gomez, JA, Dougherty, PM, Tsai, KY, Allison, JP, Sharma, P, Wargo, J, Myers, JN, Gross, N, Amit, M. Inflammation induced by tumor-associated nerves promotes resistance to anti-PD-1 therapy in cancer patients and is targetable by interleukin-6 blockade. Research square, 2023. e-Pub 2023. PMID: 37503252.
      116. Hasanov M, Milton DR, Davies AB, Sirmans E, Saberian C, Posada EL, Opusunju S, Gershenwald JE, Torres-Cabala CA, Burton EM, Colen RR, Huse JT, Glitza Oliva IC, Chung C, McAleer MF, McGovern SL, Yeboa DN, Kim BYS, Prabhu SS, McCutcheon IE, Weinberg JS, Lang FF, Tawbi HA, Li J, Haydu LE, Davies MA, Ferguson SD. Changes in Outcomes and Factors Associated with Survival in Melanoma Patients with Brain Metastases. Neuro Oncol 25(7):1310-1320, 2023. e-Pub 2023. PMID: 36510640.
      117. Slogrove AL, Davies MA, Phelanyane F, De Beer S, Theron G, Williams PL, Abrams EJ, Cotton MF, Boulle A. Hypertensive disorders of pregnancy and HIV: analysis of a province-wide cohort during 2018 and 2019. AIDS 37(7):1047-1055, 2023. e-Pub 2023. PMID: 36779497.
      118. Haas AD, Lienhard R, Didden C, Cornell M, Folb N, Boshomane TMG, Salazar-Vizcaya L, Ruffieux Y, Nyakato P, Wettstein AE, Tlali M, Davies MA, von Groote P, Wainberg M, Egger M, Maartens G, Joska JA. Mental Health, ART Adherence, and Viral Suppression Among Adolescents and Adults Living with HIV in South Africa: A Cohort Study. AIDS Behav 27(6):1849-1861, 2023. e-Pub 2023. PMID: 36592251.
      119. Kassanjee R, Davies MA, Ngwenya O, Osei-Yeboah R, Jacobs T, Morden E, Timmerman V, Britz S, Mendelson M, Taljaard J, Riou J, Boulle A, Tiffin N, Zinyakatira N. COVID-19 among adults living with HIV: correlates of mortality among public sector healthcare users in Western Cape, South Africa. J Int AIDS Soc 26(6):e26104, 2023. e-Pub 2023. PMID: 37339333.
      120. Han A, Mukha D, Chua V, Purwin TJ, Tiago M, Modasia B, Baqai U, Aumiller JL, Bechtel N, Hunter E, Danielson M, Terai M, Wedegaertner PB, Sato T, Landreville S, Davies MA, Kurtenbach S, Harbour JW, Schug ZT, Aplin AE. Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth. Cancers (Basel) 15(13), 2023. e-Pub 2023. PMID: 37444561.
      121. Yuan P, Teng D, de Groot E, Li M, Trousil S, Shen CH, Roszik J, Davies MA, Gopal YNV, Zheng B. Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis. iScience 26(6):106791, 2023. e-Pub 2023. PMID: 37213225.
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      219. Ogata D, Haydu LE, Glitza IC, Patel SP, Tawbi HA, McQuade JL, Diab A, Ekmekcioglu S, Wong MK, Davies MA, Amaria RN. The efficacy of anti-programmed cell death protein 1 therapy among patients with metastatic acral and metastatic mucosal melanoma. Cancer Medicine 10(7):2293-2299, 2021. e-Pub 2021. PMID: 33686688.
      220. Tegally H, Wilkinson E, Giovanetti M, Iranzadeh A, Fonseca V, Giandhari J, Doolabh D, Pillay S, San EJ, Msomi N, Mlisana K, von Gottberg A, Walaza S, Allam M, Ismail A, Mohale T, Glass AJ, Engelbrecht S, Van Zyl G, Preiser W, Petruccione F, Sigal A, Hardie D, Marais G, Hsiao NY, Korsman S, Davies MA, Tyers L, Mudau I, York D, Maslo C, Goedhals D, Abrahams S, Laguda-Akingba O, Alisoltani-Dehkordi A, Godzik A, Wibmer CK, Sewell BT, Lourenco J, Alcantara LCJ, Kosakovsky Pond SL, Weaver S, Martin D, Lessells RJ, Bhiman JN, Williamson C, de Oliveira T. Detection of a SARS-CoV-2 variant of concern in South Africa. Nature 592(7854):438-443, 2021. e-Pub 2021. PMID: 33690265.
      221. Cheng LY, Haydu LE, Song P, Nie J, Tetzlaff MT, Kwong LN, Gershenwald JE, Davies MA, Zhang DY. High sensitivity sanger sequencing detection of BRAF mutations in metastatic melanoma FFPE tissue specimens. Sci Rep 11(1):9043, 2021. e-Pub 2021. PMID: 33907234.
      222. Moodley K, Blockman M, Pienaar D, Hawkridge AJ, Meintjes J, Davies MA, London L. Hard choices: Ethical challenges in phase 1 of COVID-19 vaccine roll-out in South Africa. S Afr Med J 111(6):554-558, 2021. e-Pub 2021. PMID: 34382565.
      223. Desmonde S, Ciaranello AL, Malateste K, Musick B, Patten G, Vu AT, Edmonds A, Neilan AM, Duda SN, Wools-Kaloustian K, Davies MA, Leroy V. Age-specific mortality rate ratios in adolescents and youth aged 10-24 years living with perinatally versus nonperinatally acquired HIV. AIDS 35(4):625-632, 2021. e-Pub 2021. PMID: 33252479.
      224. Syeda MM, Wiggins JM, Corless BC, Long GV, Flaherty KT, Schadendorf D, Nathan PD, Robert C, Ribas A, Davies MA, Grob JJ, Gasal E, Squires M, Marker M, Garrett J, Brase JC, Polsky D. Circulating tumour DNA measurements predict survival in patients with unresectable or metastatic melanoma treated with dabrafenib or dabrafenib plus trametinib. The Lancet Oncology 22(3):370-380, 2021. e-Pub 2021. PMID: 33587894.
      225. Fukumura K, Malgulwar PB, Fischer GM, Hu X, Mao X, Song X, Hernandez SD, Zhang XH, Zhang J, Parra ER, Yu D, Debeb BG, Davies MA, Huse JT. Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasis. Acta Neuropathol 141(2):303-321, 2021. e-Pub 2021. PMID: 33394124.
      226. Menzies AM, Amaria RN, Rozeman EA, Huang AC, Tetzlaff MT, van de Wiel BA, Lo S, Tarhini AA, Burton EM, Pennington TE, Saw RPM, Xu X, Karakousis GC, Ascierto PA, Spillane AJ, van Akkooi ACJ, Mitchell TC, Tawbi HA, Scolyer RA, Davies MA, Wargo JA, Long GV. Pathological response and survival with neoadjuvant therapy in melanoma: a pooled analysis from the International Neoadjuvant Melanoma Consortium (INMC). Nat Med 27(2):301-309, 2021. e-Pub 2021. PMID: 33558722.
      227. Ujeneza EL, Ndifon W, Sawry S, Fatti G, Riou J, Davies MA, Nieuwoudt M. A mechanistic model for long-term immunological outcomes in South African HIV-infected children and adults receiving ART. Elife 10, 2021. e-Pub 2021. PMID: 33443013.
      228. Fischer GM, Guerrieri RA, Hu Q, Joon AY, Kumar S, Haydu LE, McQuade JL, Vashisht Gopal YN, Knighton B, Deng W, Hudgens CW, Lazar AJ, Tetzlaff MT, Davies MA. Clinical, molecular, metabolic, and immune features associated with oxidative phosphorylation in melanoma brain metastases. Neurooncol Adv 3(1):vdaa177, 2021. e-Pub 2021. PMID: 33575655.
      229. Somasundaram R, Connelly T, Choi R, Somasundaram R, Connelly T, Choi R, Choi H, Samarkina A, Li L, Gregorio E, Chen Y, Thakur R, Abdel-Mohsen M, Beqiri M, Kiernan M, Perego M, Wang F, Xiao M, Brafford P, Yang X, Xu X, Secreto A, Danet-Desnoyers G, Traum D, Kaestner KH, Huang AC, Hristova D, Wang J, Fukunaga-Kalabis M, Krepler C, Ping-Chen F, Zhou X, Gutierrez A, Rebecca VW, Vonteddu P, Dotiwala F, Bala S, Majumdar S, Dweep H, Wickramasinghe J, Kossenkov AV, Reyes-Arbujas J, Santiago K, Nguyen T, Griss J, Keeney F, Hayden J, Gavin BJ, Weiner D, Montaner LJ, Liu Q, Peiffer L, Becker J, Burton EM, Davies MA, Tetzlaff MT, Muthumani K, Wargo JA, Gabrilovich D, Herlyn M. Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy. Nature Communications 12(1):346, 2021. e-Pub 2021. PMID: 33436641.
      230. Woo XY, Giordano J, Srivastava A, Zhao ZM, Lloyd MW, de Bruijn R, Suh YS, Patidar R, Chen L, Scherer S, Bailey MH, Yang CH, Cortes-Sanchez E, Xi Y, Wang J, Wickramasinghe J, Kossenkov AV, Rebecca VW, Sun H, Mashl RJ, Davies SR, Jeon R, Frech C, Randjelovic J, Rosains J, Galimi F, Bertotti A, Lafferty A, O'Farrell AC, Modave E, Lambrechts D, Ter Brugge P, Serra V, Marangoni E, El Botty R, Kim H, Kim JI, Yang HK, Lee C, Dean DA, Davis-Dusenbery B, Evrard YA, Doroshow JH, Welm AL, Welm BE, Lewis MT, Fang B, Roth JA, Meric-Bernstam F, Herlyn M, Davies MA, Ding L, Li S, Govindan R, Isella C, Moscow JA, Trusolino L, Byrne AT, Jonkers J, Bult CJ, Medico E, Chuang JH, Consortium P, Consortium E. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nat Genet 53(1):86-99, 2021. e-Pub 2021. PMID: 33414553.
      231. White MG, Szczepaniak Sloane R, Witt RG, Reuben A, Gaudreau PO, Andrews MC, Feng N, Johnson S, Class CA, Bristow C, Wani K, Hudgens C, Nezi L, Manzo T, De Macedo MP, Hu J, Davis R, Jiang H, Prieto P, Burton E, Hwu P, Tawbi H, Gershenwald J, Lazar AJ, Tetzlaff MT, Overwijk W, Woodman SE, Cooper ZA, Marszalek JR, Davies MA, Heffernan TP, Wargo JA. Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in Braf-mutated melanoma. Oncoimmunology 10(1):1992880, 2021. e-Pub 2021. PMID: 34777916.
      232. Hartley LJ, Evans S, Davies MA, Kelly S, Gregory JJ. A Daily Diagnostic Multidisciplinary Meeting to Reduce Time to Definitive Diagnosis in the Context of Primary Bone and Soft Tissue Sarcoma. J Multidiscip Healthc 14:115-123, 2021. e-Pub 2021. PMID: 33488087.
      233. Hussey H, Zinyakatira N, Morden E, Ismail M, Paleker M, Bam JL, London L, Boulle A, Davies MA. Higher COVID-19 mortality in low-income communities in the City of Cape Town - a descriptive ecological study. Gates Open Res 5:90, 2021. e-Pub 2021. PMID: 34286217.
      234. Cloete K, Davies MA, Kariem S, Bouille A, Vallabhjee K, Chopra M. Opportunities during COVID-19 towards achieving Universal Health Coverage. J Glob Health 11:03115, 2021. e-Pub 2021. PMID: 34956632.
      235. Ding Z, Ogata D, Roszik J, Qin Y, Kim SH, Tetzlaff MT, Lazar AJ, Davies MA, Ekmekcioglu S, Grimm EA. iNOS Associates with Poor Survival in Melanoma: A Role for Nitric Oxide in the PI3K-AKT Pathway Stimulation and PTEN S-Nitrosylation. Front Oncol 11:631766, 2021. e-Pub 2021. PMID: 33643925.
      236. Tsondai PR, Braithwaite K, Fatti G, Bolton Moore C, Chimbetete C, Rabie H, Phiri S, Sawry S, Eley B, Hobbins MA, Boulle A, Taghavi K, Sohn AH, Davies MA. Characteristics and outcomes of adolescents living with perinatally acquired HIV within Southern Africa. AIDS 34(15):2275-2284, 2020. e-Pub 2020. PMID: 32910063.
      237. Haas AD, Technau KG, Pahad S, Braithwaite K, Madzivhandila M, Sorour G, Sawry S, Maxwell N, von Groote P, Tlali M, Davies MA, Egger M. Mental health, substance use and viral suppression in adolescents receiving ART at a paediatric HIV clinic in South Africa. J Int AIDS Soc 23(12):e25644, 2020. e-Pub 2020. PMID: 33283916.
      238. Peters SM, Davies MA, Van As AB. Repeat injuries in childhood. S Afr Med J 110(12):1218-1225, 2020. e-Pub 2020. PMID: 33403969.
      239. Kalk E, Heekes A, Mehta U, de Waal R, Jacob N, Cohen K, Myer L, Davies MA, Maartens G, Boulle A. Safety and Effectiveness of Isoniazid Preventive Therapy in Pregnant Women Living with Human Immunodeficiency Virus on Antiretroviral Therapy: An Observational Study Using Linked Population Data. Clin Infect Dis 71(8):e351-e358, 2020. e-Pub 2020. PMID: 31900473.
      240. Nguyen MQ, Teh JLF, Purwin TJ, Chervoneva I, Davies MA, Nathanson KL, Cheng PF, Levesque MP, Dummer R, Aplin AE. Targeting PHGDH Upregulation Reduces Glutathione Levels and Resensitizes Resistant NRAS-Mutant Melanoma to MAPK Kinase Inhibition. Journal of Investigative Dermatology 140(11):2242-2252.e7, 2020. e-Pub 2020. PMID: 32389536.
      241. Abdul Jalil MF, Dower A, Tawfik S, Brooks M, Davies MA, Ghahreman A. MRI predictors of revision surgery after primary lumbar discectomy. J Clin Neurosci 81:442-446, 2020. e-Pub 2020. PMID: 33222960.
      242. Desmonde S, Neilan AM, Musick B, Patten G, Chokephaibulkit K, Edmonds A, Duda SN, Malateste K, Wools-Kaloustian K, Ciaranello AL, Davies MA, Leroy V. Time-varying age- and CD4-stratified rates of mortality and WHO stage 3 and stage 4 events in children, adolescents and youth 0 to 24 years living with perinatally acquired HIV, before and after antiretroviral therapy initiation in the paediatric IeDEA Global Cohort Consortium. J Int AIDS Soc 23(10):e25617, 2020. e-Pub 2020. PMID: 33034417.
      243. Zhao W, Li J, Chen MM, Luo Y, Ju Z, Nesser NK, Johnson-Camacho K, Boniface CT, Lawrence Y, Pande NT, Davies MA, Herlyn M, Muranen T, Zervantonakis IK, von Euw E, Schultz A, Kumar SV, Korkut A, Spellman PT, Akbani R, Slamon DJ, Gray JW, Brugge JS, Lu Y, Mills GB, Liang H. Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines. Cancer Cell. e-Pub 2020. PMID: 33157050.
      244. Fischer GM, Carapeto FCL, Joon AY, Haydu LE, Chen H, Wang F, Van Arnam JS, McQuade JL, Wani K, Kirkwood JM, Thompson JF, Tetzlaff MT, Lazar AJ, Tawbi HA, Gershenwald JE, Scolyer RA, Long GV, Davies MA. Molecular and immunological associations of elevated serum lactate dehydrogenase in metastatic melanoma patients: A fresh look at an old biomarker. Cancer Med. e-Pub 2020. PMID: 33016647.
      245. Das I, Chen H, Maddalo G, Tuominen R, Rebecca VW, Herlyn M, Hansson J, Davies MA, Egyházi Brage S. Inhibiting insulin and mTOR signaling by afatinib and crizotinib combination fosters broad cytotoxic effects in cutaneous malignant melanoma. Cell Death Dis 11(10):882, 2020. e-Pub 2020. PMID: 33082316.
      246. Haas AD, Ruffieux Y, van den Heuvel LL, Lund C, Boulle A, Euvrard J, Orrell C, Prozesky HW, Tiffin N, Lovero KL, Tlali M, Davies MA, Wainberg ML. Excess mortality associated with mental illness in people living with HIV in Cape Town, South Africa: a cohort study using linked electronic health records. Lancet Glob Health 8(10):e1326-e1334, 2020. e-Pub 2020. PMID: 32971055.
      247. Jaiswal AR, Liu AJ, Pudakalakatti S, Dutta P, Jayaprakash P, Bartkowiak T, Ager CR, Wang ZQ, Reuben A, Cooper ZA, Ivan C, Ju Z, Nwajei F, Wang J, Davies MA, Davis RE, Wargo JA, Bhattacharya PK, Hong DS, Curran MA. Melanoma Evolves Complete Immunotherapy Resistance through the Acquisition of a Hypermetabolic Phenotype. Cancer Immunol Res. e-Pub 2020. PMID: 32917656.
      248. Johnson LF, Patrick M, Stephen C, Patten G, Dorrington RE, Maskew M, Jamieson L, Davies MA. Steep Declines in Pediatric AIDS Mortality in South Africa, Despite Poor Progress Toward Pediatric Diagnosis and Treatment Targets. Pediatr Infect Dis J 39(9):843-848, 2020. e-Pub 2020. PMID: 32433224.
      249. Eriksson H, Hansson J, Krynitz B, Masucci G, Girnita A, Lapins J, Huen AO, Tawbi HA, MA D, Tetzlaff MT, Curry JL. Bullous Pemphigoid-like Eruption Triggered by Targeted Therapy for Metastatic Melanoma. Acta Derm Venereol. e-Pub 2020. PMID: 32985676.
      250. Pundole X, Jones AL, Tetzlaff MT, Williams MD, Murphy WA, Otun A, Goepfert RP, Davies MA. Osteonecrosis of the jaw induced by treatment with anti-PD-1 immunotherapy: a case report. Immunotherapy. e-Pub 2020. PMID: 32900256.
      251. Tymejczyk O, Brazier E, Wools-Kaloustian K, Davies MA, Dilorenzo M, Edmonds A, Vreeman R, Bolton C, Twizere C, Okoko N, Phiri S, Nakigozi G, Lelo P, von Groote P, Sohn AH, Nash D. Impact of Universal Antiretroviral Treatment Eligibility on Rapid Treatment Initiation Among Young Adolescents with Human Immunodeficiency Virus in Sub-Saharan Africa. J Infect Dis 222(5):755-764, 2020. e-Pub 2020. PMID: 31682261.
      252. Bell-Gorrod H, Fox MP, Boulle A, Prozesky H, Wood R, Tanser F, Davies MA, Schomaker M. The Impact of Delayed Switch to Second-Line Antiretroviral Therapy on Mortality, Depending on Definition of Failure Time and CD4 Count at Failure. Am J Epidemiol 189(8):811-819, 2020. e-Pub 2020. PMID: 32219384.
      253. Ramos RI, Bustos MA, Wu J, Jones P, Chang SC, Kiyohara E, Tran K, Zhang X, Stern SL, Izraely S, Sagi-Assif O, Witz IP, Davies MA, Mills GB, Kelly DF, Irie RF, Hoon DSB. Upregulation of Cell Surface GD3 Ganglioside Phenotype Associates with Human Melanoma Brain Metastasis. Mol Oncol 14(8), 2020. e-Pub 2020. PMID: 32358995.
      254. Davies MA. HIV and risk of COVID-19 death: a population cohort study from the Western Cape Province, South Africa. medRxiv, 2020. e-Pub 2020. PMID: 32637972.
      255. Tetzlaff MT, Adhikari C, Lo S, Rawson RV, Amaria RN, Menzies AM, Wilmott JS, Ferguson PM, Ross MI, Spillane AJ, Vu KA, Ma J, Ning J, Haydu L, Saw RPM, Wargo JA, Tawbi HA, Gershenwald JE, Long GV, Davies MA, Scolyer R.A. Histopathological features of complete pathological response predict recurrence-free survival following neoadjuvant targeted therapy for metastatic melanoma. Ann Oncol. e-Pub 2020. PMID: 32739408.
      256. Patten G, Puthanakit T, McGowan CC, Wools-Kaloustian K, Hazra R, Pinto JA, Machado D, Succi R, Sohn AH, Rabie H, Musick B, Davies MA. Raltegravir use and outcomes among children and adolescents living with HIV in the IeDEA global consortium. J Int AIDS Soc 23(7):e25580, 2020. e-Pub 2020. PMID: 32722897.
      257. Zaniewski E, Dao Ostinelli CH, Chammartin F, Maxwell N, Davies MA, Euvrard J, van Dijk J, Bosomprah S, Phiri S, Tanser F, Sipambo N, Muhairwe J, Fatti G, Prozesky H, Wood R, Ford N, Fox MP, Egger M. Trends in CD4 and viral load testing 2005 to 2018: multi-cohort study of people living with HIV in Southern Africa. J Int AIDS Soc 23(7):e25546, 2020. e-Pub 2020. PMID: 32640106.
      258. Ngo B, Kim E, Osorio-Vasquez V, Doll S, Bustraan S, Liang RJ, Luengo A, Davidson SM, Ali A, Ferraro GB, Fischer GM, Eskandari R, Kang DS, Ni J, Plasger A, Rajasekhar VK, Kastenhuber ER, Bacha S, Sriram RK, Stein BD, Bakhoum SF, Snuderl M, Cotzia P, Healey JH, Mainolfi N, Suri V, Friedman A, Manfredi M, Sabatini DM, Jones DR, Yu M, Zhao JJ, Jain RK, Keshari KR, Davies MA, Vander Heiden MG, Hernando E, Mann M, Cantley LC, Pacold ME. Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition. Cancer Discovery. e-Pub 2020. PMID: 32571778.
      259. Chen D, Barsoumian H, Fischer G, Yang L, Verma V, Younes A, Hu Y, Masropour F, Klein K, Vellano C, Marszalek J, Davies MA, Cortez M, Welsh J. Combination treatment with radiotherapy and a novel oxidative phosphorylation inhibitor overcomes PD-1 resistance and enhances antitumor immunity. Journal for ImmunoTherapy of Cancer 8(1):e000289, 2020. e-Pub 2020. PMID: 32581056.
      260. Jesson J, Desmonde S, Yiannoutsos CT, Patten G, Malateste K, Duda SN, Kumarasamy N, Yotebieng M, Davies MA, Musick B, Leroy V, Ciaranello A. Weight-for-age distributions among children with HIV on antiretroviral therapy in the International epidemiology Databases to Evaluate AIDS (IeDEA) multiregional consortium. BMC Res Notes 13(1):249, 2020. e-Pub 2020. PMID: 32448379.
      261. Chammartin F, Dao Ostinelli CH, Anastos K, Jaquet A, Brazier E, Brown S, Dabis F, Davies MA, Duda SN, Malateste K, Nash D, Wools-Kaloustian K, von Groote PM, Egger M. International epidemiology databases to evaluate AIDS (IeDEA) in sub-Saharan Africa, 2012-2019. BMJ Open 10(5):e035246, 2020. e-Pub 2020. PMID: 32414825.
      262. Haydu LE, Lo SN, McQuade JL, Amaria RN, Wargo J, Ross MI, Cormier JN, Lucci A, Lee JE, Ferguson SD, Saw RPM, Spillane AJ, Shannon KF, Stretch JR, Hwu P, Patel SP, Diab A, Wong MKK, Glitza Oliva IC, Tawbi H, Carlino MS, Menzies AM, Long GV, Lazar AJ, Tetzlaff MT, Scolyer RA, Gershenwald JE, Thompson JF, Davies MA. Cumulative Incidence and Predictors of CNS Metastasis for Patients With American Joint Committee on Cancer 8th Edition Stage III Melanoma. J Clin Oncol 38(13):1429-1441, 2020. e-Pub 2020. PMID: 31990608.
      263. Kehoe K, Boulle A, Tsondai PR, Euvrard J, Davies MA, Cornell M. Long-term virologic responses to antiretroviral therapy among HIV-positive patients entering adherence clubs in Khayelitsha, Cape Town, South Africa: a longitudinal analysis. J Int AIDS Soc 23(5):e25476, 2020. e-Pub 2020. PMID: 32406983.
      264. Teh JLF, Purwin TJ, Han A, Chua V, Patel P, Baqai U, Liao C, Bechtel N, Sato T, Davies MA, Aguirre-Ghiso J, Aplin AE. Metabolic adaptations to MEK and CDK4/6 co-targeting in uveal melanoma. Molecular Cancer Therapeutics, 2020. e-Pub 2020. PMID: 32430489.
      265. Davies MJ, Davies MA, Sharpe R, Cordato D, Schwartz R. Epidural Blood Patch as a Diagnostic and Therapeutic Intervention in Spontaneous Intracranial Hypotension: A Novel Approach to Management. World Neurosurg 137:e242-e250, 2020. e-Pub 2020. PMID: 32004736.
      266. Davies MAM, Lawrence T, Edwards A, Lecky F, McKay CD, Stokes KA, Williams S. Serious sports-related injury in England and Wales from 2012-2017: a study protocol. Inj Epidemiol 7(1):14, 2020. e-Pub 2020. PMID: 32336291.
      267. Lucci A, Hall CS, Patel SP, Narendran B, Bauldry JB, Royal RE, Karhade M, Upshaw JR, Wargo JA, Glitza IC, Wong MKK, Amaria RN, Tawbi HA, Diab A, Davies MA, Gershenwald JE, Lee JE, Hwu P, Ross MI. Circulating tumor cells and early relapse in node-positive melanoma. Clin Cancer Res 26(8):1886-1895, 2020. e-Pub 2020. PMID: 32015020.
      268. Mitra A, Andrews MC, Roh W, De Macedo MP, Hudgens CW, Carapeto F, Singh S, Reuben A, Wang F, Mao X, Song X, Wani K, Tippen S, Ng KS, Schalck A, Sakellariou-Thompson DA, Chen E, Reddy SM, Spencer CN, Wiesnoski D, Little LD, Gumbs C, Cooper ZA, Burton EM, Hwu P, Davies MA, Zhang J, Bernatchez C, Navin N, Sharma P, Allison JP, Wargo JA, Yee C, Tetzlaff MT, Hwu WJ, Lazar AJ, Futreal PA. Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma. Nat Commun 11(1):1839, 2020. e-Pub 2020. PMID: 32296058.
      269. Drummond KJ, Hunn BHM, McAlpine HE, Jones JJ, Davies MA, Gull S. Challenges in the Australasian neurosurgery training program: who should be trained and where should they train?. Neurosurg Focus 48(3):E10, 2020. e-Pub 2020. PMID: 32114546.
      270. Nagarajan P, Piao J, Ning J, Noordenbos LE, Curry JL, Torres-Cabala CA, Diwan AH, Ivan D, Aung PP, Ross MI, Royal RE, Wargo JA, Wang WL, Samdani R, Lazar AJ, Rashid A, Davies MA, Prieto VG, Gershenwald JE, Tetzlaff MT. Prognostic model for patient survival in primary anorectal mucosal melanoma: stage at presentation determines relevance of histopathologic features. Mod Pathol 33(3):496-513, 2020. e-Pub 2020. PMID: 31383963.
      271. Tiago M, Capparelli C, Erkes DA, Purwin TJ, Heilman SA, Berger AC, Davies MA, Aplin AE. Targeting BRD/BET proteins inhibits adaptive kinome upregulation and enhances the effects of BRAF/MEK inhibitors in melanoma. Br J Cancer 122(6):789-800, 2020. e-Pub 2020. PMID: 31932756.
      272. Wang DY, McQuade JL, Rai RR, Park JJ, Zhao S, Ye F, Beckermann KE, Rubinstein SM, Johnpulle R, Long GV, Carlino MS, Menzies AM, Davies MA, Johnson DB. The Impact of Nonsteroidal Anti-Inflammatory Drugs, Beta Blockers, and Metformin on the Efficacy of Anti-PD-1 Therapy in Advanced Melanoma. Oncologist 25(3):e602-e605, 2020. e-Pub 2020. PMID: 32162820.
      273. Iyun V, Technau KG, Eley B, Rabie H, Boulle A, Fatti G, Egger M, Tanser F, Wood R, Fairlie L, Cotton MF, Davies MA. Earlier Antiretroviral Therapy Initiation and Decreasing Mortality Among HIV-infected Infants Initiating Antiretroviral Therapy Within 3 Months of Age in South Africa, 2006-2017. Pediatr Infect Dis J 39(2):127-133, 2020. e-Pub 2020. PMID: 31725119.
      274. Holbrook K, Lutzky J, Davies MA, Davis JM, Glitza IC, Amaria RN, Diab A, Patel SP, Amin A, Tawbi H. Intracranial Anti-Tumor Activity with Encorafenib Plus Binimetinib in Patients with Melanoma Brain Metastases: A Case Series. Cancer 126(3):523-530, 2020. e-Pub 2020. PMID: 31658370.
      275. Helmink BA, Reddy SM, Gao J, Zhang S, Basar R, Thakur R, Yizhak K, Sade-Feldman M, Blando J, Han G, Gopalakrishnan V, Xi Y, Zhao H, Amaria RN, Tawbi HA, Cogdill AP, Liu W, LeBleu VS, Kugeratski FG, Patel S, Davies MA, Hwu P, Lee JE, Gershenwald JE, Lucci A, Arora R, Woodman S, Keung EZ, Gaudreau PO, Reuben A, Spencer CN, Burton EM, Haydu LE, Lazar AJ, Zapassodi R, Hudgens CW, Ledesma DA, Ong S, Bailey M, Warren S, Rao D, Krijgsman O, Rozeman EA, Peeper D, Blank CU, Schumacher TN, Butterfield LH, Zelazowska MA, McBride KM, Kalluri R, Allison J, Petitprez F, Fridman WH, Sautès-Fridman C, Hacohen N, Rezvani K, Sharma P, Tetzlaff MT, Wang L, Wargo JA. B cells and tertiary lymphoid structures promote immunotherapy response. Nature, 2020. e-Pub 2020. PMID: 31942075.
      276. Davies MA. Cleansing-induced changes in skin measured by in vivo confocal raman spectroscopy. Skin Res Technol 26(1):30-38, 2020. e-Pub 2020. PMID: 31373073.
      277. de Beer S, Kalk E, Kroon M, Boulle A, Osler M, Euvrard J, Timmerman V, Davies MA. A longitudinal analysis of the completeness of maternal HIV testing, including repeat testing in Cape Town, South Africa. J Int AIDS Soc 23(1):e25441, 2020. e-Pub 2020. PMID: 31997583.
      278. Tsondai PR, Sohn AH, Phiri S, Sikombe K, Sawry S, Chimbetete C, Fatti G, Hobbins MA, Technau KG, Rabie H, Bernheimer J, Fox MP, Judd A, Collins IJ, Davies MA. Characterizing the double-sided cascade of care for adolescents living with HIV transitioning to adulthood across Southern Africa. J Int AIDS Soc 23(1):e25447, 2020. e-Pub 2020. PMID: 32003159.
      279. Rosenbaum SR, Knecht M, Mollaee M, Zhong Z, Erkes DA, McCue PA, Chervoneva I, Berger AC, Lo JA, Fisher DE, Gershenwald JE, Davies MA, Purwin TJ, Aplin AE. FOXD3 regulates VISTA expression in melanoma. Cell Rep 30(2):510-524.e6, 2020. e-Pub 2020. PMID: 31940493.
      280. Nyakato P, Davies MA, Technau KG, Fatti G, Rabie H, Tanser F, Boulle A, Wood R, Eley B, Sawry S, Giddy J, Sipambo N, Kuhn L, Fairlie L. Virologic response to efavirenz-based first-line antiretroviral therapy in children with previous exposure to antiretrovirals to prevent mother-to-child transmission. PLoS One 15(5):e0233693, 2020. e-Pub 2020. PMID: 32469985.
      281. Boettiger DC, Law MG, Sohn AH, Davies MA, Wools-Kaloustian K, Leroy V, Yotebieng M, Vinikoor M, Vreeman R, Amorissani-Folquet M, Edmonds A, Fatti G, Batte J, Renner L, Adedimeji A, Kariminia A. Temporal Trends in Co-trimoxazole Use Among Children on Antiretroviral Therapy and the Impact of Co-trimoxazole on Mortality Rates in Children Without Severe Immunodeficiency. J Pediatric Infect Dis Soc 8(5):450-460, 2019. e-Pub 2019. PMID: 30215763.
      282. Vashisht Gopal YN, Gammon ST, Prasad R, Knighton B, Pisaneschi F, Roszik J, Feng N, Johnson S, Pramanik S, Sudderth J, Sui D, Hudgens CW, Fischer GM, Deng W, Reuben A, Peng W, Wang J, Di Francesco ME, Marszalek JR, McQuade JL, Tetzlaff MT, Piwnica-Worms D, DeBerardinis RJ, Davies MA. A novel mitochondrial inhibitor blocks MAPK pathway and overcomes MAPK inhibitor-resistance in melanoma. Clin Cancer Res, 2019. e-Pub 2019. PMID: 31439581.
      283. Safa H, Johnson DH, Trinh VA, Rodgers TE, Lin H, Suarez-Almazor ME, Fa'ak F, Saberian C, Yee C, Davies MA, Tummala S, Woodman K, Abdel-Wahab N, Diab A. Immune Checkpoint Inhibitor Related Myasthenia Gravis: Single Center Experience and Systematic Review of the Literature. J Immunother Cancer 7(1):319, 2019. e-Pub 2019. PMID: 31753014.
      284. Gammon ST, Pisaneschi F, Bandi ML, Smith MG, Sun Y, Rao Y, Muller F, Wong F, De Groot J, Ackroyd J, Mawlawi O, Davies MA, Gopal YNV, Di Francesco ME, Marszalek JR, Dewhirst M, Piwnica-Worms D. Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [18F]FAZA PET In Vivo. Cells 8(12), 2019. e-Pub 2019. PMID: 31766580.
      285. Jesson J, Schomaker M, Malasteste K, Wati DK, Kariminia A, Sylla M, Kouadio K, Sawry S, Mubiana-Mbewe M, Ayaya S, Vreeman R, McGowan CC, Yotebieng M, Leroy V, Davies MA. Stunting and growth velocity of adolescents with perinatally acquired HIV: differential evolution for males and females. A multiregional analysis from the IeDEA global paediatric collaboration. J Int AIDS Soc 22(11):e25412, 2019. e-Pub 2019. PMID: 31702088.
      286. Schomaker M, Luque-Fernandez MA, Leroy V, Davies MA. Using longitudinal targeted maximum likelihood estimation in complex settings with dynamic interventions. Stat Med 38(24):4888-4911, 2019. e-Pub 2019. PMID: 31436859.
      287. Davies MAM, Kerr ZY, DeFreese JD, Arden NK, Marshall SW, Guskiewicz KM, Padua DA, Pietrosimone B. Prevalence of and Risk Factors for Total Hip and Knee Replacement in Retired National Football League Athletes. Am J Sports Med 47(12):2863-2870, 2019. e-Pub 2019. PMID: 31498654.
      288. Mackinnon AL, Jackson K, Kuznik K, Turner A, Hill J, Davies MAM, Jones ME, Delmestri A, Sanchez-Santos MT, Newton J. Increased Risk of Musculoskeletal Disorders and Mental Health Problems in Retired Professional Jockeys: A Cross-Sectional Study. Int J Sports Med 40(11):732-738, 2019. e-Pub 2019. PMID: 31390657.
      289. Mackinnon AL, Jackson K, Kuznik K, Turner A, Hill J, Davies MAM, Jones ME, Delmestri A, Sanchez-Santos MT, Newton J. Increased Risk of Musculoskeletal Disorders and Mental Health Problems in Retired Professional Jockeys: A Cross-Sectional Study. Int J Sports Med 40(14):e5, 2019. e-Pub 2019. PMID: 31480087.
      290. Sanchez IM, Purwin TJ, Chervoneva I, Erkes DA, Nguyen MQ, Davies MA, Nathanson KL, Kemper K, Peeper DS, Aplin AE. In vivo ERK1/2 reporter predictively models response and resistance to combined BRAF and MEK inhibitors in melanoma. Mol Cancer Ther, 2019. e-Pub 2019. PMID: 31270153.
      291. AbuHammad S, Cullinane C, Martin C, Bacolas Z, Ward T, Chen H, Slater A, Ardley K, Kirby L, Chan KT, Brajanovski N, Smith LK, Rao AD, Lelliott EJ, Kleinschmidt M, Vergara IA, Papenfuss AT, Lau P, Ghosh P, Haupt S, Haupt Y, Sanij E, Poortinga G, Pearson RB, Falk H, Curtis DJ, Stupple P, Devlin M, Street I, Davies MA, McArthur GA, Sheppard KE. Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma. Proc Natl Acad Sci U S A, 2019. e-Pub 2019. PMID: 31439820.
      292. Kircher DA, Trombetti KA, Silvis MR, Parkman GL, Fischer GM, Angel SN, Stehn CM, Strain SC, Grossmann AH, Duffy KL, Boucher KM, McMahon M, Davies MA, Mendoza MC, VanBrocklin MW, Holmen SL. AKT1E17K activates focal adhesion kinase and promotes melanoma brain metastasis. Mol Cancer Res, 2019. e-Pub 2019. PMID: 31138602.
      293. Peng W, Williams LJ, Xu C, Melendez B, McKenzie JA, Chen Y, Jackson H, Voo KS, Mbofung RM, Leahey SE, Wang J, Lizee G, Tawbi HA, Davies MA, Hoos A, Smothers J, Srinivasan R, Paul EM, Yanamandra N, Hwu P. Anti-OX40 antibody directly enhances the function of tumor-reactive CD8+ T cells and synergizes with PI3Kβ inhibition in PTEN loss melanoma. Clin Cancer Res. e-Pub 2019. PMID: 31371342.
      294. Jones ME, Davies MAM, Shah K, Kemp S, Peirce N, Leyland KM, Stokes KA, Judge AD, Newton JL, Furniss D, Arden NK. The prevalence of hand and wrist osteoarthritis in elite former cricket and rugby union players. J Sci Med Sport 22(8):871-875, 2019. e-Pub 2019. PMID: 30940442.
      295. Schvartsman G, Ma J, Bassett RL, Haydu LE, Amaria RN, Hwu P, Wong MK, Hwu WJ, Diab A, Patel SP, Davies MA, Hamerschlak N, Tawbi HA, Glitza Oliva IC. Incidence, patterns of progression, and outcomes of preexisting and newly discovered brain metastases during treatment with anti-PD-1 in patients with metastatic melanoma. Cancer. e-Pub 2019. PMID: 31398264.
      296. Robert C, Grob JJ, Stroyakovskiy D, Karaszewska B, Hauschild A, Levchenko E, Chiarion Sileni V, Schachter J, Garbe C, Bondarenko I, Gogas H, Mandalá M, JBAG H, Lebbé C, Mackiewicz A, Rutkowski P, Nathan PD, Ribas A, Davies MA, Flaherty KT, Burgess P, Tan M, Gasal E, Voi M, Schadendorf D, Long GV. Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma. N Engl J Med, 2019. e-Pub 2019. PMID: 31166680.
      297. Ascierto PA, Agarwala SS, Botti G, Budillon A, Davies MA, Dummer R, Ernstoff M, Ferrone S, Formenti S, Gajewski TF, Garbe C, Hamid O, Lo RS, Luke JJ, Michielin O, Palmieri G, Zitvogel L, Marincola FM, Masucci G, Caracò C, Thurin M, Puzanov I. Perspectives in melanoma: meeting report from the Melanoma Bridge (November 29th-1 December 1st, 2018, Naples, Italy). J Transl Med 17(1):234, 2019. e-Pub 2019. PMID: 31331337.
      298. Tymejczyk O, Brazier E, Yiannoutsos CT, Vinikoor M, van Lettow M, Nalugoda F, Urassa M, Sinayobye JD, Rebeiro PF, Wools-Kaloustian K, Davies MA, Zaniewski E, Anderegg N, Liu G, Ford N, Nash D. Changes in rapid HIV treatment initiation after national "treat all" policy adoption in 6 sub-Saharan African countries: Regression discontinuity analysis. PLoS Med 16(6):e1002822, 2019. e-Pub 2019. PMID: 31181056.
      299. Msukwa MT, Keiser O, Jahn A, van Oosterhout JJ, Edmonds A, Phiri N, Manjomo R, Davies MA, Estill J. Timing of combination antiretroviral therapy (cART) initiation is not associated with stillbirth among HIV-infected pregnant women in Malawi. Trop Med Int Health 24(6):727-735, 2019. e-Pub 2019. PMID: 30891866.
      300. Ferguson SD, Bindal S, Bassett RL, Haydu LE, McCutcheon IE, Heimberger AB, Li J, O'Brien BJ, Guha-Thakurta N, Tetzlaff MT, Tawbi H, Davies MA, Glitza IC. Predictors of survival in metastatic melanoma patients with leptomeningeal disease (LMD). J Neurooncol 142(3):499-509, 2019. e-Pub 2019. PMID: 30847840.
      301. Fischer GM, Jalali A, Kircher DA, Lee WC, McQuade JL, Haydu LE, Joon AY, Reuben A, de Macedo MP, Carapeto FCL, Yang C, Srivastava A, Ambati CR, Sreekumar A, Hudgens CW, Knighton B, Deng W, Ferguson SD, Tawbi HA, Glitza IC, Gershenwald JE, Vashisht Gopal YN, Hwu P, Huse JT, Wargo JA, Futreal PA, Putluri N, Lazar AJ, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL, Tetzlaff MT, Davies MA. Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. Cancer Discov 9(5):628-645, 2019. e-Pub 2019. PMID: 30787016.
      302. Karz, A., Dimitrova, M, Alvarez-Breckenridge, C., Atkins, M. B., Boire, A., Bosenberg, M., Brastianos, P., Cahill, D. P., Chen, Q, Ferguson, S., Forsyth, P., Glitza Oliva, I. C., Goldberg, S. B., Najjar YG, Holmen, S. L., Knisely, J. P. S., Merlino, G., Pacold, M. E., Perez-Guijarro, E., Smalley, K. S. M., Tawbi, H. A., Wen, P. Y., Davies, M. A., Kluger, H. M., Mehnert, J. M., Davies MA, Hernando, E.. Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities. Pigment Cell Melanoma Res 32(3):458-469, 2019. e-Pub 2019. PMID: 30712316.
      303. Kluger HM, Margolin KA, Davies MA, Long GV, Tawbi HA, Goldberg SB, Chiang VL. Reply to A. Shinde et al. J Clin Oncol 37(12):JCO1802463, 2019. e-Pub 2019. PMID: 30807233.
      304. Patten G, Schomaker M, Davies MA, Rabie H, van Zyl G, Technau K, Eley B, Boulle A, Van Dyke RB, Patel K, Sipambo N, Wood R, Tanser F, Giddy J, Cotton M, Nuttall J, Essack G, Karalius B, Seage G, Sawry S, Egger M, Fairlie L. What Should We Do When HIV-positive Children Fail First-line Combination Antiretroviral Therapy? A Comparison of 4 ART Management Strategies. Pediatr Infect Dis J 38(4):400-405, 2019. e-Pub 2019. PMID: 30882732.
      305. Euvrard J, Schulz T, Hilderbrand K, Bosland M, Osler M, Boulle A, Davies MA. How accurately do routinely reported HIV viral load suppression proportions reflect progress towards the 90-90-90 target in the population on antiretroviral treatment in Khayelitsha, South Africa?. S Afr Med J 109(3):174-177, 2019. e-Pub 2019. PMID: 30834874.
      306. Yotebieng M, Brazier E, Addison D, Kimmel AD, Cornell M, Keiser O, Parcesepe AM, Onovo A, Lancaster KE, Castelnuovo B, Murnane PM, Cohen CR, Vreeman RC, Davies MA, Duda SN, Yiannoutsos CT, Bono RS, Agler R, Bernard C, Syvertsen JL, Sinayobye JD, Wikramanayake R, Sohn AH, von Groote PM, Wandeler G, Leroy V, Williams CF, Wools-Kaloustian K, Nash D. Research priorities to inform "Treat All" policy implementation for people living with HIV in sub-Saharan Africa: a consensus statement from the International epidemiology Databases to Evaluate AIDS (IeDEA). J Int AIDS Soc 22(1):e25218, 2019. e-Pub 2019. PMID: 30657644.
      307. Chihana ML, Huerga H, Van Cutsem G, Ellman T, Goemaere E, Wanjala S, Masiku C, Szumilin E, Etard JF, Maman D, Davies MA. Distribution of advanced HIV disease from three high HIV prevalence settings in Sub-Saharan Africa: a secondary analysis data from three population-based cross-sectional surveys in Eshowe (South Africa), Ndhiwa (Kenya) and Chiradzulu (Malawi). Glob Health Action 12(1):1679472, 2019. e-Pub 2019. PMID: 31679482.
      308. Anderson K, Muloiwa R, Davies MA. Treatment outcomes in perinatally infected HIV-positive adolescents and young adults after >/=10 years on antiretroviral therapy. S Afr Med J 109(1):27-34, 2018. e-Pub 2018. PMID: 30606301.
      309. Kariminia A, Law M, Davies MA, Vinikoor M, Wools-Kaloustian K, Leroy V, Edmonds A, McGowan C, Vreeman R, Fairlie L, Ayaya S, Yotebieng M, Takassi E, Pinto J, Adedimeji A, Malateste K, Machado DM, Penazzato M, Hazra R, Sohn AH. Mortality and losses to follow-up among adolescents living with HIV in the IeDEA global cohort collaboration. J Int AIDS Soc 21(12):e25215, 2018. e-Pub 2018. PMID: 30548817.
      310. Teh JLF, Cheng PF, Purwin TJ, Nikbakht N, Patel P, Chervoneva I, Ertel A, Fortina PM, Kleiber I, HooKim K, Davies MA, Kwong LN, Levesque MP, Dummer R, Aplin AE. Correction: In Vivo E2F Reporting Reveals Efficacious Schedules of MEK1/2-CDK4/6 Targeting and mTOR-S6 Resistance Mechanisms. Cancer Discov 8(12):1654, 2018. e-Pub 2018. PMID: 30510016.
      311. Ferguson SD, Zheng S, Xiu J, Zhou S, Khasraw M, Brastianos PK, Kesari S, Hu J, Rudnick J, Salacz ME, Piccioni D, Huang S, Davies MA, Glitza IC, Heymach JV, Zhang J, Ibrahim NK, DeGroot JF, McCarty J, O'Brien BJ, Sawaya R, Verhaak RGW, Reddy SK, Priebe W, Gatalica Z, Spetzler D, Heimberger AB. Profiles of Brain Metastases: Prioritization of Therapeutic Targets. Int J Cancer 143(11):3019-3026, 2018. e-Pub 2018. PMID: 29923182.
      312. Kalk E, Kroon M, Boulle A, Osler M, Euvrard J, Stinson K, Timmerman V, Davies MA. Neonatal and infant diagnostic HIV-PCR uptake and associations during three sequential policy periods in Cape Town, South Africa: a longitudinal analysis. J Int AIDS Soc 21(11):e25212, 2018. e-Pub 2018. PMID: 30480373.
      313. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA. Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med 24(11):1649-1654, 2018. e-Pub 2018. PMID: 30297909.
      314. Kugel CH, Douglass SM, Webster MR, Kaur A, Liu Q, Yin X, Weiss SA, Darvishian F, Al-Rohil RN, Ndoye A, Behera R, Alicea GM, Ecker BL, Fane M, Allegrezza MJ, Svoronos N, Kumar V, Wang DY, Somasundaram R, Hu-Lieskovan S, Ozgun A, Herlyn M, Conejo-Garcia JR, Gabrilovich D, Stone EL, Nowicki TS, Sosman J, Rai R, Carlino MS, Long GV, Marais R, Ribas A, Eroglu Z, Davies MA, Schilling B, Schadendorf D, Xu W, Amaravadi RK, Menzies AM, McQuade JL, Johnson DB, Osman I, Weeraratna AT. Age Correlates with Response to Anti-PD1, Reflecting Age-Related Differences in Intratumoral Effector and Regulatory T-Cell Populations. Clin Cancer Res 24(21):5347-5356, 2018. e-Pub 2018. PMID: 29898988.
      315. Childress MA, Himmelberg SM, Chen H, Deng W, Davies MA, Lovly CM. ALK Fusion Partners Impact Response to ALK Inhibition: Differential Effects on Sensitivity Cellular phenotypes, and Biochemical Properties. Mol Cancer Res 16(11):1724-1736, 2018. e-Pub 2018. PMID: 30002191.
      316. Panayidou K, Davies MA, Anderegg N, Egger M. Global temporal changes in the proportion of children with advanced disease at the start of combination antiretroviral therapy in an era of changing criteria for treatment initiation. J Int AIDS Soc 21(11):e25200, 2018. e-Pub 2018. PMID: 30614622.
      317. Capparelli C, Purwin TJ, Heilman SA, Chervoneva I, McCue PA, Berger AC, Davies MA, Gershenwald JE, Krepler C, Aplin AE. ErbB3 Targeting Enhances the Effects of MEK Inhibitor in Wild-Type BRAF/NRAS Melanoma. Cancer Res 78(19):5680-5693, 2018. e-Pub 2018. PMID: 30115691.
      318. Johnson DH, Zobniw CM, Trinh VA, Ma J, Bassett RL, Abdel-Wahab N, Anderson J, Davis JE, Joseph J, Uemura M, Noman A, Abu-Sbeih H, Yee C, Amaria R, Patel S, Tawbi H, Glitza IC, Davies MA, Wong MK, Woodman S, Hwu WJ, Hwu P, Wang Y, Diab A. Infliximab associated with faster symptom resolution compared with corticosteroids alone for the management of immune-related enterocolitis. J Immunother Cancer 6(1):103, 2018. e-Pub 2018. PMID: 30305177.
      319. Barken R, Denton M, Sayin FK PhD candidate, Brookman C, Davies S MA, Zeytinoglu IU. The influence of autonomy on personal support workers' job satisfaction, capacity to care, and intention to stay. Home Health Care Serv Q 37(4):294-312, 2018. e-Pub 2018. PMID: 30321126.
      320. Msukwa MT, Estill J, Haas AD, van Oosterhout JJ, Tenthani L, Davies MA, Tal K, Phiri N, Spoerri A, Mthiko BC, Chimbwandira F, Keiser O. Weight gain of HIV-exposed, uninfected children born before and after introduction of the 'Option B+' programme in Malawi. AIDS 32(15):2201-2208, 2018. e-Pub 2018. PMID: 30005013.
      321. Woyton MM, Kluzek S, Wedatilake T, Davies MAM. Partial mid-portion Achilles tear resulting in substantial improvement in pain and function in an amateur long-distance runner. BMJ Case Rep 2018, 2018. e-Pub 2018. PMID: 30232204.
      322. Brennan AT, Bor J, Davies MA, Wandeler G, Prozesky H, Fatti G, Wood R, Stinson K, Tanser F, Barnighausen T, Boulle A, Sikazwe I, Zanolini A, Fox MP. Medication Side Effects and Retention in HIV Treatment: A Regression Discontinuity Study of Tenofovir Implementation in South Africa and Zambia. Am J Epidemiol 187(9):1990-2001, 2018. e-Pub 2018. PMID: 29767681.
      323. McQuade JL, Davies MA. Estrogen returns to the stage in melanoma. Pigment Cell Melanoma Res 31(5):554-555, 2018. e-Pub 2018. PMID: 29665231.
      324. Bezrookove V, Nosrati M, Miller JR, De Semir D, Dar AA, Vosoughi E, Vaquero E, Sucker A, Lazar AJ, Gershenwald JE, Davies MA, Schadendorf D, Kashani-Sabet M. Role of Elevated PHIP Copy Number as a Prognostic and Progression Marker for Cutaneous Melanoma. Clin Cancer Res 24(17):4119-4125, 2018. e-Pub 2018. PMID: 29776954.
      325. Forget MA, Haymaker C, Hess KR, Meng YJ, Creasy C, Karpinets T, Fulbright OJ, Roszik J, Woodman SE, Kim YU, Sakellariou-Thompson D, Bhatta A, Wahl A, Flores E, Thorsen ST, Tavera RJ, Ramachandran R, Gonzalez AM, Toth CL, Wardell S, Mansaray R, Patel V, Carpio DJ, Vaughn C, Farinas CM, Velasquez PG, Hwu WJ, Patel SP, Davies MA, Diab A, Glitza IC, Tawbi H, Wong MK, Cain S, Ross MI, Lee JE, Gershenwald JE, Lucci A, Royal R, Cormier JN, Wargo JA, Radvanyi LG, Torres-Cabala CA, Beroukhim R, Hwu P, Amaria RN, Bernatchez C. Prospective analysis of adoptive TIL therapy in patients with metastatic melanoma: response, impact of anti-CTLA4, and biomarkers to predict clinical outcome. Clin Cancer Res 24(18):4416-4428, 2018. e-Pub 2018. PMID: 29848573.
      326. Vishnoi M, Boral D, Liu H, Sprouse ML, Yin W, Goswami-Sewell D, Tetzlaff MT, Davies MA, Oliva ICG, Marchetti D. Targeting USP7 identifies a metastasis-competent state within bone marrow-resident melanoma CTCs. Cancer Res 78(18):5349-5362, 2018. e-Pub 2018. PMID: 30026332.
      327. Farley E, Stewart A, Davies MA, Govind M, Van den Bergh D, Boyles TH. Antibiotic use and resistance: Knowledge, attitudes and perceptions among primary care prescribers in South Africa. S Afr Med J 108(9):763-771, 2018. e-Pub 2018. PMID: 30182902.
      328. Sohn AH, Judd A, Mofenson L, Vicari M, Jerene D, Leroy V, Bekker LG, Davies MA. Using Observational Data to Inform HIV Policy Change for Children and Youth. J Acquir Immune Defic Syndr 78 Suppl 1(1):S22-S26, 2018. e-Pub 2018. PMID: 29994916.
      329. Tetzlaff MT, Messina JL, Stein JE, Xu X, Amaria RN, Blank CU, van de Wiel BA, Ferguson PM, Rawson RV, Ross MI, Spillane AJ, Gershenwald JE, Saw RPM, van Akkooi ACJ, van Houdt WJ, Mitchell TC, Menzies AM, Long GV, Wargo JA, Davies MA, Prieto VG, Taube JM, Scolyer RA. Pathological assessment of resection specimens after neoadjuvant therapy for metastatic melanoma. Ann Oncol 29(8):1861-1868, 2018. e-Pub 2018. PMID: 29945191.
      330. Steinhaus N, Al-Talib M, Ive P, Boyles T, Bamford C, Davies MA, Mendelson M, Wasserman S. The management and outcomes of Staphylococcus aureus bacteraemia at a South African referral hospital: A prospective observational study. Int J Infect Dis 73:78-84, 2018. e-Pub 2018. PMID: 29908251.
      331. Huang L, Malu S, McKenzie JA, Andrews MC, Talukder AH, Tieu T, Karpinets T, Haymaker C, Forget MA, Williams LJ, Wang Z, Mbofung RM, Wang ZQ, Davis RE, Lo RS, Wargo JA, Davies MA, Bernatchez C, Heffernan T, Amaria RN, Korkut A, Peng W, Roszik J, Lizée G, Woodman SE, Hwu P. The RNA-binding protein MEX3B mediates resistance to cancer immunotherapy by downregulating HLA-A expression. Clin Cancer Res 24(14):3366-3376, 2018. e-Pub 2018. PMID: 29496759.
      332. Ballester LY, Glitza Oliva IC, Douse DY, Chen MM, Lan C, Haydu LE, Huse JT, Roy-Chowdhuri S, Luthra R, Wistuba II, Davies MA. Evaluating Circulating Tumor DNA From the Cerebrospinal Fluid of Patients With Melanoma and Leptomeningeal Disease. J Neuropathol Exp Neurol 77(7):628-635, 2018. e-Pub 2018. PMID: 29873738.
      333. Arrive E, Ayaya S, Davies MA, Chimbetete C, Edmonds A, Lelo P, Fong SM, Razali KA, Kouakou K, Duda SN, Leroy V, Vreeman RC. Models of support for disclosure of HIV status to HIV-infected children and adolescents in resource-limited settings. J Int AIDS Soc 21(7):e25157, 2018. e-Pub 2018. PMID: 29972632.
      334. Ascierto PA, Puzanov I, Agarwala SS, Bifulco C, Botti G, Caracò C, Ciliberto G, Davies MA, Dummer R, Ferrone S, Gajewski TF, Garbe C, Luke JJ, Marincola FM, Masucci G, Mehnert JM, Mozzillo N, Palmieri G, Postow MA, Schoenberger SP, Wang E, Thurin M. Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy). J Transl Med 16(1):207, 2018. e-Pub 2018. PMID: 30031393.
      335. Wools-Kaloustian K, Marete I, Ayaya S, Sohn AH, Van Nguyen L, Li S, Leroy V, Musick BS, Newman JE, Edmonds A, Davies MA, Eboua FT, Obama MT, Yotebieng M, Sawry S, Mofenson LM, Yiannoutsos CT. Time to First-Line ART Failure and Time to Second-Line ART Switch in the IeDEA Pediatric Cohort. J Acquir Immune Defic Syndr 78(2):221-230, 2018. e-Pub 2018. PMID: 29509590.
      336. Jones ME, Davies MAM, Leyland KM, Delmestri A, Porter A, Ratcliffe J, Peirce N, Newton JL, Arden NK. Osteoarthritis and other long-term health conditions in former elite cricketers. J Sci Med Sport 21(6):558-563, 2018. e-Pub 2018. PMID: 29089246.
      337. Cascone T, McKenzie JA, Mbofung RM, Punt S, Wang Z, Xu C, Williams LJ, Wang Z, Bristow CA, Carugo A, Peoples MD, Li L, Karpinets T, Huang L, Malu S, Creasy C, Leahey SE, Chen J, Chen Y, Pelicano H, Bernatchez C, Gopal YNV, Heffernan TP, Hu J, Wang J, Amaria RN, Garraway LA, Huang P, Yang P, Wistuba II, Woodman SE, Roszik J, Davis RE, Davies MA, Heymach JV, Hwu P, Peng W. Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy. Cell Metab 27(5):977-987.e4, 2018. e-Pub 2018. PMID: 29628419.
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      396. Kim DW, Haydu LE, Joon AY, Bassett RL, Siroy AE, Tetzlaff MT, Routbort MJ, Amaria RN, Wargo JA, McQuade JL, Kemnade J, Hwu P, Woodman SE, Roszik J, Kim KB, Gershenwald JE, Lazar AJ, Davies MA. Clinicopathological features and clinical outcomes associated with TP53 and BRAF (Non-V600) mutations in cutaneous melanoma patients. Cancer 123(8):1372-1381, 2017. e-Pub 2017. PMID: 27911979.
      397. Mahy M, Penazzato M, Ciaranello A, Mofenson L, Yianoutsos CT, Davies MA, Stover J. Improving estimates of children living with HIV from the Spectrum AIDS Impact Model. AIDS 31 Suppl 1(Suppl 1):S13-S22, 2017. e-Pub 2017. PMID: 28301337.
      398. Cheng H, Chua V, Liao C, Purwin TJ, Terai M, Kageyama K, Davies MA, Sato T, Aplin AE. Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma. Mol Cancer Ther 16(3):516-528, 2017. e-Pub 2017. PMID: 28138035.
      399. Roh W, Chen PL, Reuben A, Spencer CN, Prieto PA, Miller JP, Gopalakrishnan V, Wang F, Cooper ZA, Reddy SM, Gumbs C, Little L, Chang Q, Chen WS, Wani K, De Macedo MP, Chen E, Austin-Breneman JL, Jiang H, Roszik J, Tetzlaff MT, Davies MA, Gershenwald JE, Tawbi H, Lazar AJ, Hwu P, Hwu WJ, Diab A, Glitza IC, Patel SP, Woodman SE, Amaria RN, Prieto VG, Hu J, Sharma P, Allison JP, Chin L, Zhang J, Wargo JA, Futreal PA. Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance. Sci Transl Med 9(379), 2017. e-Pub 2017. PMID: 28251903.
      400. Shiuan E, Beckermann KE, Ozgun A, Kelly C, McKean M, McQuade J, Thompson MA, Puzanov I, Greer JP, Rapisuwon S, Postow M, Davies MA, Eroglu Z, Johnson D. Thrombocytopenia in patients with melanoma receiving immune checkpoint inhibitor therapy. J Immunother Cancer 5:8, 2017. e-Pub 2017. PMID: 28239462.
      401. Brennan AT, Bor J, Davies MA, Conradie F, Maskew M, Long L, Sanne I, Fox MP. Tenofovir stock shortages have limited impact on clinic- and patient-level HIV treatment outcomes in public sector clinics in South Africa. Trop Med Int Health 22(2):241-251, 2017. e-Pub 2017. PMID: 27862762.
      402. Li J, Zhao W, Akbani R, Liu W, Ju Z, Ling S, Vellano CP, Roebuck P, Yu Q, Eterovic AK, Byers LA, Davies MA, Deng W, Gopal YN, Chen G, von Euw EM, Slamon D, Conklin D, Heymach JV, Gazdar AF, Minna JD, Myers JN, Lu Y, Mills GB, Liang H. Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays. Cancer Cell 31(2):225-239, 2017. e-Pub 2017. PMID: 28196595.
      403. Menzies AM, Johnson DB, Ramanujam S, Atkinson VG, Wong ANM, Park JJ, McQuade JL, Shoushtari AN, Tsai KK, Eroglu Z, Klein O, Hassel JC, Sosman JA, Guminski A, Sullivan RJ, Ribas A, Carlino MS, Davies MA, Sandhu SK, Long GV. Anti-PD-1 therapy in patients with advanced melanoma and preexisting autoimmune disorders or major toxicity with ipilimumab. Ann Oncol 28(2):368-376, 2017. e-Pub 2017. PMID: 27687304.
      404. Brennan AT, Davies MA, Bor J, Wandeler G, Stinson K, Wood R, Prozesky H, Tanser F, Fatti G, Boulle A, Sikazwe I, Wool-Kaloustian K, Yuannoutsos C, Leroy V, de Rekeneire N, Fox MP. Has the phasing out of stavudine in accordance with changes in WHO guidelines led to a decrease in single-drug substitutions in first-line antiretroviral therapy for HIV in sub-Saharan Africa?. AIDS 31(1):147-157, 2017. e-Pub 2017. PMID: 27776039.
      405. Davies MA. An in vivo confocal Raman spectroscopic investigation of salicylic acid penetration: Variation with formulation parameters. J Cosmet Sci 68(1):55-58, 2017. e-Pub 2017. PMID: 29465383.
      406. Vettus E, Draper D, Davies MA. Metastatic Melanoma Responding to Combination Chemotherapy and Immunotherapy After Progression on Ipilimumab and Nivolumab Immunotherapy. Annals of Clinical Case Reports. e-Pub 2017.
      407. Reuben A, Petaccia de Macedo M, McQuade J, Joon A, Ren Z, Calderone T, Conner B, Wani K, Cooper ZA, Tawbi H, Tetzlaff MT, Padera RF, Durand JB, Lazar AJ, Wargo JA, Davies MA. Comparative immunologic characterization of autoimmune giant cell myocarditis with ipilimumab. Oncoimmunology 6(12):e1361097, 2017. e-Pub 2017. PMID: 29209563.
      408. Davies MAM, Balai E, Adams J, Carter JH, Judge A, Newton JL, Arden NK. The consultation of rugby players in co-developing a player health study: feasibility and consequences of sports participants as research partners. Res Involv Engagem 3:8, 2017. e-Pub 2017. PMID: 29062533.
      409. Fortuin-de Smidt M, de Waal R, Cohen K, Technau KG, Stinson K, Maartens G, Boulle A, Igumbor EU, Davies MA. First-line antiretroviral drug discontinuations in children. PLoS One 12(2):e0169762, 2017. e-Pub 2017. PMID: 28192529.
      410. McQuade JL, Posada LP, Lecagoonporn S, Cain S, Bassett RL, Patel SP, Hwu WJ, Hwu P, Davies MA, Bedikian AY, Amaria RN. A phase I study of TPI 287 in combination with temozolomide for patients with metastatic melanoma. Melanoma Res 26(6):604-608, 2016. e-Pub 2016. PMID: 27540836.
      411. Long GV, Grob JJ, Nathan P, Ribas A, Robert C, Schadendorf D, Lane SR, Mak C, Legenne P, Flaherty KT, Davies MA. Factors predictive of response, disease progression, and overall survival after dabrafenib and trametinib combination treatment: a pooled analysis of individual patient data from randomised trials. Lancet Oncol 17(12):1621-1754, 2016. e-Pub 2016. PMID: 27864013.
      412. Douis H, Davies MA, Sian P. The role of diffusion-weighted MRI (DWI) in the differentiation of benign from malignant skeletal lesions of the pelvis. Eur J Radiol 85(12):2262-2268, 2016. e-Pub 2016. PMID: 27842675.
      413. Rohner E, Schmidlin K, Zwahlen M, Chakraborty R, Clifford G, Obel N, Grabar S, Verbon A, Noguera-Julian A, Collins IJ, Rojo P, Brockmeyer N, Campbell M, Chene G, Prozesky H, Eley B, Stefan DC, Davidson A, Chimbetete C, Sawry S, Davies MA, Kariminia A, Vibol U, Sohn A, Egger M, Bohlius J. Kaposi Sarcoma Risk in HIV-Infected Children and Adolescents on Combination Antiretroviral Therapy From Sub-Saharan Africa, Europe, and Asia. Clin Infect Dis 63(9):1245-1253, 2016. e-Pub 2016. PMID: 27578823.
      414. Ascierto PA, Agarwala S, Botti G, Cesano A, Ciliberto G, Davies MA, Demaria S, Dummer R, Eggermont AM, Ferrone S, Fu YX, Gajewski TF, Garbe C, Huber V, Khleif S, Krauthammer M, Lo RS, Masucci G, Palmieri G, Postow M, Puzanov I, Silk A, Spranger S, Stroncek DF, Tarhini A, Taube JM, Testori A, Wang E, Wargo JA, Yee C, Zarour H, Zitvogel L, Fox BA, Mozzillo N, Marincola FM, Thurin M. Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015. J Transl Med 14(1):313, 2016. e-Pub 2016. PMID: 27846884.
      415. Tripp MK, Gershenwald JE, Davies MA, Garcia J, Gritz ER, Hawk ET, Peterson SK. Assessment of Compliance With Texas Legislation Banning Indoor UV Tanning by Minors. JAMA Dermatol. e-Pub 2016. PMID: 27829081.
      416. Krepler C, Xiao M, Samanta M, Vultur A, Chen HY, Brafford P, Reyes-Uribe PI, Halloran M, Chen T, He X, Hristova D, Liu Q, Samatar AA, Davies MA, Nathanson KL, Fukunaga-Kalabis M, Herlyn M, Villanueva J. Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma. Oncotarget 7(44):71211-71222, 2016. e-Pub 2016. PMID: 27655717.
      417. Vinikoor MJ, Mulenga L, Siyunda A, Musukuma K, Chilengi R, Moore CB, Chi BH, Davies MA, Egger M, Wandeler G. Association between hepatitis B co-infection and elevated liver stiffness among HIV-infected adults in Lusaka, Zambia. Trop Med Int Health 21(11):1435-1441, 2016. e-Pub 2016. PMID: 27499385.
      418. Johnson LF, Keiser O, Fox MP, Tanser F, Cornell M, Hoffmann CJ, Prozesky H, Boulle A, Davies MA. Life expectancy trends in adults on antiretroviral treatment in South Africa. AIDS 30(16):2545-2550, 2016. e-Pub 2016. PMID: 27428744.
      419. Roszik J, Haydu LE, Hess KR, Oba J, Joon AY, Siroy AE, Karpinets TV, Stingo FC, Baladandayuthapani V, Tetzlaff MT, Wargo JA, Chen K, Forget MA, Haymaker CL, Chen JQ, Meric-Bernstam F, Eterovic AK, Shaw KR, Mills GB, Gershenwald JE, Radvanyi LG, Hwu P, Futreal PA, Gibbons DL, Lazar AJ, Bernatchez C, Davies MA, Woodman SE. Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set. BMC Med 14(1):168, 2016. e-Pub 2016. PMID: 27776519.
      420. Rachlis B, Karwa R, Chema C, Pastakia S, Olsson S, Wools-Kaloustian K, Jakait B, Maina M, Yotebieng M, Kumarasamy N, Freeman A, de Rekeneire N, Duda SN, Davies MA, Braitstein P. Targeted Spontaneous Reporting: Assessing Opportunities to Conduct Routine Pharmacovigilance for Antiretroviral Treatment on an International Scale. Drug Saf 39(10):959-76, 2016. e-Pub 2016. PMID: 27282427.
      421. Teh JL, Purwin TJ, Greenawalt EJ, Chervoneva I, Goldberg A, Davies MA, Aplin AE. An in vivo reporter to quantitatively and temporally analyze the effects of CDK4/6 inhibitor-based therapies in melanoma. Cancer Res 76(18):5455-66, 2016. e-Pub 2016. PMID: 27488531.
      422. Davies MA, Gibb D, Turkova A. Survival of HIV-1 vertically infected children. Curr Opin HIV AIDS 11(5):455-464, 2016. e-Pub 2016. PMID: 27716730.
      423. Tetzlaff MT, Singh RR, Seviour EG, Curry JL, Hudgens CW, Bell D, Wimmer DA, Ning J, Czerniak BA, Zhang L, Davies MA, Prieto VG, Broaddus RR, Ram P, Luthra R, Esmaeli B. Next-generation sequencing identifies high frequency of mutations in potentially clinically actionable genes in sebaceous carcinoma. J Pathol 240(1):84-95, 2016. e-Pub 2016. PMID: 27287813.
      424. Chen G, McQuade JL, Panka DJ, Hudgens CW, Amin-Mansour A, Mu XJ, Bahl S, Jané-Valbuena J, Wani KM, Reuben A, Creasy CA, Jiang H, Cooper ZA, Roszik J, Bassett RL, Joon AY, Simpson LM, Mouton RD, Glitza IC, Patel SP, Hwu WJ, Amaria RN, Diab A, Hwu P, Lazar AJ, Wargo JA, Garraway LA, Tetzlaff MT, Sullivan RJ, Kim KB, Davies MA. Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial. JAMA Oncol 2(8):1056-64, 2016. e-Pub 2016. PMID: 27124486.
      425. Chen PL, Roh W, Reuben A, Cooper ZA, Spencer CN, Prieto PA, Miller JP, Bassett RL, Gopalakrishnan V, Wani K, De Macedo MP, Austin-Breneman JL, Jiang H, Chang Q, Reddy SM, Chen WS, Tetzlaff MT, Broaddus RJ, Davies MA, Gershenwald JE, Haydu L, Lazar AJ, Patel SP, Hwu P, Hwu WJ, Diab A, Glitza IC, Woodman SE, Vence LM, Wistuba II, Amaria RN, Kwong LN, Prieto V, Davis RE, Ma W, Overwijk WW, Sharpe AH, Hu J, Futreal PA, Blando J, Sharma P, Allison JP, Chin L, Wargo JA. Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade. Cancer Discov 6(8):827-37, 2016. e-Pub 2016. PMID: 27301722.
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      427. Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, Atkins MB, Bosenberg MW, Dummer R, Gershenwald JE, Halpern AC, Herlyn D, Karakousis GC, Kirkwood JM, Krauthammer M, Lo RS, Long GV, McArthur G, Ribas A, Schuchter L, Sosman JA, Smalley KS, Steeg P, Thomas NE, Tsao H, Tueting T, Weeraratna A, Xu G, Lomax R, Martin A, Silverstein S, Turnham T, Ronai ZA. The State of Melanoma: Challenges and Opportunities. Pigment Cell Melanoma Res 29(4):404-16, 2016. e-Pub 2016. PMID: 27087480.
      428. Bohlius J, Maxwell N, Spoerri A, Wainwright R, Sawry S, Poole J, Eley B, Prozesky H, Rabie H, Garone D, Technau KG, Maskew M, Davies MA, Davidson A, Stefan DC, Egger M. Incidence of AIDS-defining and Other Cancers in HIV-positive Children in South Africa: Record Linkage Study. Pediatr Infect Dis J 35(6):e164-70, 2016. e-Pub 2016. PMID: 26906162.
      429. Goedert L, Pereira CG, Roszik J, Plaça JR, Cardoso C, Chen G, Deng W, Yennu-Nanda VG, Silva WA, Davies MA, Espreafico EM. RMEL3, a novel BRAFV600E-associated long noncoding RNA, is required for MAPK and PI3K signaling in melanoma. Oncotarget 7(24):36711-36718, 2016. e-Pub 2016. PMID: 27167340.
      430. Ekmekcioglu S, Davies MA, Tanese K, Roszik J, Shin-Sim M, Bassett RL, Milton DR, Woodman SE, Prieto VG, Gershenwald JE, Morton DL, Hoon DS, Grimm EA. Inflammatory Marker Testing Identifies CD74 Expression in Melanoma Tumor Cells, and its Expression Associates with Favorable Survival for Stage III Melanoma. Clin Cancer Res 22(12):3016-24, 2016. e-Pub 2016. PMID: 26783288.
      431. Zhang G, Frederick DT, Wu L, Wei Z, Krepler C, Srinivasan S, Chae YC, Xu X, Choi H, Dimwamwa E, Ope O, Shannan B, Basu D, Zhang D, Guha M, Xiao M, Randell S, Sproesser K, Xu W, Liu J, Karakousis GC, Schuchter LM, Gangadhar TC, Amaravadi RK, Gu M, Xu C, Ghosh A, Xu W, Tian T, Zhang J, Zha S, Liu Q, Brafford P, Weeraratna A, Davies MA, Wargo JA, Avadhani NG, Lu Y, Mills GB, Altieri DC, Flaherty KT, Herlyn M. Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors. J Clin Invest 126(5):1834-56, 2016. e-Pub 2016. PMID: 27043285.
      432. Meric-Bernstam F, Brusco L, Daniels M, Wathoo C, Bailey AM, Strong L, Shaw K, Lu K, Qi Y, Zhao H, Lara-Guerra H, Litton J, Arun B, Eterovic AK, Aytac U, Routbort M, Subbiah V, Janku F, Davies MA, Kopetz S, Mendelsohn J, Mills GB, Chen K. Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol. Ann Oncol 27(5):795-800, 2016. e-Pub 2016. PMID: 26787237.
      433. Sholl LM, Andea A, Bridge JA, Cheng L, Davies MA, Ehteshami M, Gangadhar TC, Kamel-Reid S, Lazar A, Raparia K, Siroy A, Watson KL, Reporting Committee MOCB, American Pathologists CO. Template for Reporting Results of Biomarker Testing of Specimens From Patients With Melanoma. Arch Pathol Lab Med 140(4):355-7, 2016. e-Pub 2016. PMID: 26340412.
      434. De Waal R, Cohen K, Fox MP, Stinson K, Maartens G, Boulle A, Davies MA. Clinician compliance with laboratory monitoring and prescribing guidelines in HIV-1-infected patients receiving tenofovir. S Afr Med J 106(4):52-3, 2016. e-Pub 2016. PMID: 27032851.
      435. Cooper ZA, Reuben A, Spencer CN, Prieto PA, Austin-Breneman JL, Jiang H, Haymaker C, Gopalakrishnan V, Tetzlaff MT, Frederick DT, Sullivan RJ, Amaria RN, Patel SP, Hwu P, Woodman SE, Glitza IC, Diab A, Vence LM, Rodriguez-Canales J, Parra ER, Wistuba II, Coussens LM, Sharpe AH, Flaherty KT, Gershenwald JE, Chin L, Davies MA, Clise-Dwyer K, Allison JP, Sharma P, Wargo JA. Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma. Oncoimmunology 5(3):e1136044, 2016. e-Pub 2016. PMID: 27141370.
      436. Tsai WB, Long Y, Park JR, Chang JT, Liu H, Rodriguez-Canales J, Savaraj N, Feun LG, Davies MA, Wistuba II, Kuo MT. Gas6/Axl is the sensor of arginine-auxotrophic response in targeted chemotherapy with arginine-depleting agents. Oncogene 35(13):1632-42, 2016. e-Pub 2016. PMID: 26096933.
      437. Schomaker M, Davies MA, Malateste K, Renner L, Sawry S, N'Gbeche S, Technau KG, Eboua F, Tanser F, Sygnate-Sy H, Phiri S, Amorissani-Folquet M, Cox V, Koueta F, Chimbete C, Lawson-Evi A, Giddy J, Amani-Bosse C, Wood R, Egger M, Leroy V. Growth and Mortality Outcomes for Different Antiretroviral Therapy Initiation Criteria in Children Ages 1-5 Years: A Causal Modeling Analysis. Epidemiology 27(2):237-46, 2016. e-Pub 2016. PMID: 26479876.
      438. Vu HL, Rosenbaum S, Capparelli C, Purwin TJ, Davies MA, Berger AC, Aplin AE. MIG6 Is MEK Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma. J Invest Dermatol 136(2):453-63, 2016. e-Pub 2016. PMID: 26967478.
      439. Peng W, Chen JQ, Liu C, Malu S, Creasy C, Tetzlaff MT, Xu C, McKenzie JA, Zhang C, Liang X, Williams LJ, Deng W, Chen G, Mbofung R, Lazar AJ, Torres-Cabala CA, Cooper ZA, Chen PL, Tieu TN, Spranger S, Yu X, Bernatchez C, Forget MA, Haymaker C, Amaria R, McQuade JL, Glitza IC, Cascone T, Li HS, Kwong LN, Heffernan TP, Hu J, Bassett RL Jr, Bosenberg MW, Woodman SE, Overwijk WW, Lizee G, Roszik J, Gajewski TF, Wargo JA, Gershenwald JE, Radvanyi L, Davies MA, Hwu P. Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy. Cancer Discov 6(2):202-16, 2016. e-Pub 2016. PMID: 26645196.
      440. Peng W, Chen JQ, Liu C, Malu S, Creasy C, Tetzlaff MT, Xu C, McKenzie JA, Zhang C, Liang X, Williams LJ, Deng W, Chen G, Mbofung R, Lazar AJ, Torres-Cabala CA, Cooper ZA, Chen PL, Tieu TN, Spranger S, Yu X, Bernatchez C, Forget MA, Haymaker C, Amaria R, McQuade JL, Glitza IC, Cascone T, Li HS, Kwong LN, Heffernan TP, Hu J, Bassett RL, Bosenberg MW, Woodman SE, Overwijk WW, Lizée G, Roszik J, Gajewski TF, Wargo JA, Gershenwald JE, Radvanyi L, Davies MA, Hwu P. Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy. Cancer Discov 6(2):202-16, 2016. e-Pub 2016.
      441. Zand B, Previs RA, Zacharias NM, Rupaimoole R, Mitamura T, Nagaraja AS, Guindani M, Dalton HJ, Yang L, Baddour J, Achreja A, Hu W, Pecot CV, Ivan C, Wu SY, McCullough CR, Gharpure KM, Shoshan E, Pradeep S, Mangala LS, Rodriguez-Aguayo C, Wang Y, Nick AM, Davies MA, Armaiz-Pena G, Liu J, Lutgendorf SK, Baggerly KA, Eli MB, Lopez-Berestein G, Nagrath D, Bhattacharya PK, Sood AK. Role of Increased n-acetylaspartate Levels in Cancer. J Natl Cancer Inst 108(6):djv426, 2016. e-Pub 2016. PMID: 26819345.
      442. Roszik J, Wu CJ, Siroy AE, Lazar AJ, Davies MA, Woodman SE, Kwong LN. Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression. Sci Rep 6:19649, 2016. e-Pub 2016. PMID: 26787600.
      443. Johnson LF, Chiu C, Myer L, Davies MA, Dorrington RE, Bekker LG, Boulle A, Meyer-Rath G. Prospects for HIV control in South Africa: a model-based analysis. Glob Health Action 9:30314, 2016. e-Pub 2016. PMID: 27282146.
      444. Morden E, Technau KG, Giddy J, Maxwell N, Keiser O, Davies MA. Growth of HIV-Exposed Uninfected Infants in the First 6 Months of Life in South Africa: The IeDEA-SA Collaboration. PLoS One 11(4):e0151762, 2016. e-Pub 2016. PMID: 27049853.
      445. Feng Y, Pinkerton AB, Hulea L, Zhang T, Davies MA, Grotegut S, Cheli Y, Yin H, Lau E, Kim H, De SK, Barile E, Pellecchia M, Bosenberg M, Li JL, James B, Hassig CA, Brown KM, Topisirovic I, Ronai ZA. SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex. Cancer Res 75(75):5211-5218, 2015. e-Pub 2015. PMID: 26603897.
      446. Davies MA, Ford N, Rabie H, Fatti G, Stinson K, Giddy J, Tanser F, Technau KG, Sawry S, Eley B, Wood R, Mofenson LM, Keiser O, Boulle A. Reducing CD4 Monitoring in Children on Antiretroviral Therapy With Virologic Suppression. Pediatr Infect Dis J 34(12):1361-4, 2015. e-Pub 2015. PMID: 26379169.
      447. Hong D, Kurzrock R, Wheler JJ, Naing A, Falchook GS, Fu S, Kim KB, Davies MA, Nguyen LM, George GC, Xu L, Shumaker R, Ren M, Mink J, Bedell C, Andresen C, Sachdev P, O'Brien JP, Nemunaitis J. Phase I dose-escalation study of the multikinase inhibitor lenvatinib in patients with advanced solid tumors and in an expanded cohort of patients with melanoma. Clin Cancer Res 21(21):4801-10, 2015. e-Pub 2015. PMID: 26169970.
      448. Cho JH, Robinson JP, Arave RA, Burnett WJ, Kircher DA, Chen G, Davies MA, Grossmann AH, VanBrocklin MW, McMahon M, Holmen SL. AKT1 Activation Promotes Development of Melanoma Metastases. Cell Rep 13(5):898-905, 2015. e-Pub 2015. PMID: 26565903.
      449. Ascierto PA, Atkins M, Bifulco C, Botti G, Cochran A, Davies MA, Demaria S, Dummer R, Ferrone S, Formenti S, Gajewski TF, Garbe C, Khleif S, Kiessling R, Lo R, Lorigan P, Arthur GM, Masucci G, Melero I, Mihm M, Palmieri G, Parmiani G, Puzanov I, Romero P, Schilling B, Seliger B, Stroncek D, Taube J, Tomei S, Zarour HM, Testori A, Wang E, Galon J, Ciliberto G, Mozzillo N, Marincola FM, Thurin M. Future perspectives in melanoma research: meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014. J Transl Med 13(1):374, 2015. e-Pub 2015. PMID: 26619946.
      450. Glitza IC, Haymaker C, Bernatchez C, Vence LM, Rohlfs ML, Richard J, Lacey C, Mansaray R, Fulbright OJ, Ramachandran R, Toth C, Wardell S, Woodman SE, Patel S, Hwu WJ, Radvanyi L, Davies MA, Papadopoulos NE, Hwu P. Intrathecal administration of tumor-infiltrating lymphocytes is well tolerated in a patient with leptomeningeal disease from metastatic melanoma: A case report. Cancer Immunol Res 3(11):1201-6, 2015. e-Pub 2015. PMID: 26216417.
      451. Davies MA, Terhorst L, Zhang P, Nakonechny AJ, Nowalk MP. Pilot Study of a Computer-Based Parental Questionnaire and Visual Profile of Obesity Risk in Healthy Preschoolers. J Pediatr Nurs 30(6):e45-52, 2015. e-Pub 2015. PMID: 25813269.
      452. Davies MA. Salicylic acid deposition from wash-off products: comparison of in vivo and porcine deposition models. Int J Cosmet Sci 37(5):526-31, 2015. e-Pub 2015. PMID: 25899428.
      453. Keiser O, Blaser N, Davies MA, Wessa P, Eley B, Moultrie H, Rabie H, Technau KG, Ndirangu J, Garone D, Giddy J, Grimwood A, Gsponer T, Egger M. Growth in Virologically Suppressed HIV-Positive Children on Antiretroviral Therapy: Individual and Population-level References. Pediatr Infect Dis J 34(10):e254-9, 2015. e-Pub 2015. PMID: 26192393.
      454. Moreno FA, Erickson RP, Garriock HA, Gelernter J, Mintz J, Oas-Terpstra J, Davies MA, Delgado PL. Association Study of Genotype by Depressive Response during Tryptophan Depletion in Subjects Recovered from Major Depression. Mol Neuropsychiatry 1(3):165-174, 2015. e-Pub 2015. PMID: 26528486.
      455. Capparelli C, Rosenbaum S, Berman-Booty LD, Salhi A, Gaborit N, Zhan T, Chervoneva I, Roszik J, Woodman SE, Davies MA, Setiady YY, Osman I, Yarden Y, Aplin AE. ErbB3/ErbB2 complexes as a therapeutic target in a subset of wild-type BRAF/NRAS cutaneous melanomas. Cancer Res 75(15):3554-67, 2015. e-Pub 2015. PMID: 26206558.
      456. Vu HL, Rosenbaum S, Purwin TJ, Davies MA, Aplin AE. RAC1 P29S regulates PD-L1 expression in melanoma. Pigment Cell Melanoma Res 28(5):590-8, 2015. e-Pub 2015. PMID: 26176707.
      457. Meric-Bernstam F, Brusco L, Shaw K, Horombe C, Kopetz S, Davies MA, Routbort M, Piha-Paul SA, Janku F, Ueno N, Hong D, De Groot J, Ravi V, Li Y, Luthra R, Patel K, Broaddus R, Mendelsohn J, Mills GB. Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials. J Clin Oncol 33(25):2753-62, 2015. e-Pub 2015. PMID: 26014291.
      458. Porter M, Davies MA, Mapani MK, Rabie H, Phiri S, Nuttall J, Fairlie L, Technau KG, Stinson K, Wood R, Wellington M, Haas AD, Giddy J, Tanser F, Eley B. Outcomes of Infants Starting Antiretroviral Therapy in Southern Africa, 2004-2012. J Acquir Immune Defic Syndr 69(5):593-601, 2015. e-Pub 2015. PMID: 26167620.
      459. Tetzlaff MT, Pattanaprichakul P, Wargo J, Fox PS, Patel KP, Estrella JS, Broaddus RR, Williams MD, Davies MA, Routbort MJ, Lazar AJ, Woodman SE, Hwu WJ, Gershenwald JE, Prieto VG, Torres-Cabala CA, Curry JL. Utility of BRAF V600E immunohistochemical expression pattern as a surrogate of BRAF mutation status in 154 patients with advanced melanoma. Hum Pathol 46(8):1101-10, 2015. e-Pub 2015. PMID: 26058727.
      460. Haas AD, Keiser O, Balestre E, Brown S, Bissagnene E, Chimbetete C, Dabis F, Davies MA, Hoffmann CJ, Oyaro P, Parkes-Ratanshi R, Reynolds SJ, Sikazwe I, Wools-Kaloustian K, Zannou DM, Wandeler G, Egger M. Monitoring and switching of first-line antiretroviral therapy in adult treatment cohorts in sub-Saharan Africa: collaborative analysis. Lancet HIV 2(7):e271-8, 2015. e-Pub 2015. PMID: 26423252.
      461. Meric-Bernstam F, Johnson A, Holla V, Bailey AM, Brusco L, Chen K, Routbort M, Patel KP, Zeng J, Kopetz S, Davies MA, Piha-Paul SA, Hong DS, Eterovic AK, Tsimberidou AM, Broaddus R, Bernstam EV, Shaw KR, Mendelsohn J, Mills GB. A decision support framework for genomically informed investigational cancer therapy. J Natl Cancer Inst 107(7), 2015. e-Pub 2015. PMID: 25863335.
      462. Atlas Network CG. Genomic Classification of Cutaneous Melanoma. Cell 161(7):1681-96, 2015. e-Pub 2015. PMID: 26091043.
      463. Goswami RS, Patel KP, Singh RR, Meric-Bernstam F, Kopetz ES, Subbiah V, Alvarez RH, Davies MA, Jabbar KJ, Roy-Chowdhuri S, Lazar AJ, Medeiros LJ, Broaddus RR, Luthra R, Routbort MJ. Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors. Clin Cancer Res 21(11):2644-51, 2015. e-Pub 2015. PMID: 25695693.
      464. Bradley SD, Chen Z, Melendez B, Talukder A, Khalili JS, Rodriguez-Cruz T, Liu S, Whittington M, Deng W, Li F, Bernatchez C, Radvanyi LG, Davies MA, Hwu P, Lizée G. BRAF(V600E) co-opts a conserved MHC class I internalization pathway to diminish antigen presentation and CD8+ T-cell recognition of melanoma. Cancer Immunol Res 3(6):602-9, 2015. e-Pub 2015. PMID: 25795007.
      465. Stockman DL, Curry JL, Torres-Cabala CA, Watson IR, Siroy AE, Bassett RL, Zou L, Patel KP, Luthra R, Davies MA, Wargo JA, Routbort MA, Broaddus RR, Prieto VG, Lazar AJ, Tetzlaff MT. Use of Clinical Next-Generation Sequencing To Identify Melanomas Harboring SMARCB1 Mutations. J Cutan Pathol 42(5):308-17, 2015. e-Pub 2015. PMID: 25754356.
      466. Scortegagna M, Lau E, Zhang T, Feng Y, Sereduk C, Yin H, De SK, Meeth K, Platt JT, Langdon CG, Halaban R, Pellecchia M, Davies MA, Brown K, Stern DF, Bosenberg M, Ronai ZA. PDK1 and SGK3 contribute to the growth of BRAF mutant melanomas and are potential therapeutic targets. Cancer Res 75(7):1399-412, 2015. e-Pub 2015. PMID: 25712345.
      467. Ballif M, Renner L, Claude Dusingize J, Leroy V, Ayaya S, Wools-Kaloustian K, Cortes CP, McGowan CC, Graber C, Mandalakas AM, Mofenson LM, Egger M, Kumara Wati KD, Nallusamy R, Reubenson G, Davies MA, Fenner L. Tuberculosis in Pediatric Antiretroviral Therapy Programs in Low- and Middle-Income Countries: Diagnosis and Screening Practices. J Pediatric Infect Dis Soc 4(1):30-8, 2015. e-Pub 2015. PMID: 26407355.
      468. Pillay V, Davies MA, King S, Eley B. Short-term treatment outcomes of children starting antiretroviral therapy in the intensive care unit, general medical wards and outpatient HIV clinics at Red Cross War Memorial Children's Hospital, Cape Town, South Africa: A retrospective cohort study. S Afr Med J 105(3):220-7, 2015. e-Pub 2015. PMID: 26294831.
      469. Chen K, Meric-Bernstam F, Zhao H, Zhang Q, Ezzeddine N, Tang LY, Qi Y, Mao Y, Chen T, Chong Z, Zhou W, Zheng X, Johnson A, Aldape KD, Routbort MJ, Luthra R, Kopetz S, Davies MA, de Groot J, Moulder S, Vinod R, Farhangfar CJ, Shaw KM, Mendelsohn J, Mills GB, Eterovic AK. Clinical actionability enhanced through deep targeted sequencing of solid tumors. Clin Chem 61(3):544-53, 2015. e-Pub 2015. PMID: 25626406.
      470. Ju Z, Liu W, Roebuck PL, Siwak DR, Zhang N, Lu Y, Davies MA, Akbani R, Weinstein JN, Mills GB, Coombes KR. Development of a robust classifier for quality control of reverse-phase protein arrays. Bioinformatics 31(6):912-8, 2015. e-Pub 2015. PMID: 25380958.
      471. Siroy AE, Boland GM, Milton DR, Roszik J, Frankian S, Malke J, Haydu L, Prieto VG, Tetzlaff M, Ivan D, Wang WL, Torres-Cabala C, Curry J, Roy-Chowdhuri S, Broaddus R, Rashid A, Stewart J, Gershenwald JE, Amaria RN, Patel SP, Papadopoulos NE, Bedikian A, Hwu WJ, Hwu P, Diab A, Woodman SE, Aldape KD, Luthra R, Patel KP, Shaw KR, Mills GB, Mendelsohn J, Meric-Bernstam F, Kim KB, Routbort MJ, Lazar AJ, Davies MA. Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma. J Invest Dermatol 135(2):508-15, 2015. e-Pub 2015. PMID: 25148578.
      472. Turley RS, Tokuhisa Y, Toshimitsu H, Lidsky ME, Padussis JC, Fontanella A, Deng W, Augustine CK, Beasley GM, Davies MA, Dewhirst MW, Tyler DS. Targeting N-cadherin Increases Vascular Permeability and Differentially Activates AKT in Melanoma. Ann Surg 261(2):368-77, 2015. e-Pub 2015. PMID: 24646553.
      473. Geng EH, Neilands TB, Thiebaut R, Bwana MB, Nash D, Moore RD, Wood R, Zannou DM, Althoff KN, Lim PL, Nachega JB, Easterbrook PJ, Kambugu A, Little F, Nakigozi G, Nakanjako D, Kiggundu V, Ki Li PC, Bangsberg DR, Fox MP, Prozesky H, Hunt PW, Davies MA, Reynolds SJ, Egger M, Yiannoutsos CT, Vittinghoff EV, Deeks SG, Martin JN. CD41 T cell recovery during suppression of HIV replication: an international comparison of the immunological efficacy of antiretroviral therapy in North America, Asia and Africa. Int J Epidemiol 44(1):251-63, 2015. e-Pub 2015. PMID: 25859596.
      474. Yotebieng M, Meyers T, Behets F, Davies MA, Keiser O, Ngonyani KZ, Lyamuya RE, Kariminia A, Hansudewechakul R, Leroy V, Koumakpai S, Newman J, Van Rie A. Age-specific and sex-specific weight gain norms to monitor antiretroviral therapy in children in low-income and middle-income countries. AIDS 29(1):101-9, 2015. e-Pub 2015. PMID: 25562494.
      475. Koller M, Patel K, Chi BH, Wools-Kaloustian K, Dicko F, Chokephaibulkit K, Chimbetete C, Avila D, Hazra R, Ayaya S, Leroy V, Truong HK, Egger M, Davies MA. Immunodeficiency in children starting antiretroviral therapy in low-, middle-, and high-income countries. J Acquir Immune Defic Syndr 68(1):62-72, 2015. e-Pub 2015. PMID: 25501345.
      476. Damsky W, Micevic G, Meeth K, Muthusamy V, Curley DP, Santhanakrishnan M, Erdelyi I, Platt JT, Huang L, Theodosakis N, Zaidi MR, Tighe S, Davies MA, Dankort D, McMahon M, Merlino G, Bardeesy N, Bosenberg M. mTORC1 activation blocks Braf V600E - induced growth arrest, but is insufficient for melanoma formation. Cancer Cell 27(1):41-56, 2015. e-Pub 2015. PMID: 25584893.
      477. Johnson LF, Dorrington RE, Laubscher R, Hoffmann CJ, Wood R, Fox MP, Cornell M, Schomaker M, Prozesky H, Tanser F, Davies MA, Boulle A. A comparison of death recording by health centres and civil registration in South Africans receiving antiretroviral treatment. J Int AIDS Soc 18(1):20628, 2015. e-Pub 2015. PMID: 26685125.
      478. Davies MA, Pinto J, Bras M. Getting to 90-90-90 in paediatric HIV: What is needed?. J Int AIDS Soc 18(7Suppl 6):20770, 2015. e-Pub 2015. PMID: 28326130.
      479. Davies MA. Abstracts of the Melanoma Bridge Meeting 2014, December 3-6, 2014, Naples, Italy. J Transl Med 13 Suppl 1(Suppl 1):K1-P16, 2015. e-Pub 2015. PMID: 26056689.
      480. Davies MA. Research gaps in neonatal HIV-related care. South Afr J HIV Med 16(1):375, 2015. e-Pub 2015. PMID: 29568592.
      481. Johnson LF, Estill J, Keiser O, Cornell M, Moolla H, Schomaker M, Grimsrud A, Davies MA, Boulle A. Do increasing rates of loss to follow-up in antiretroviral treatment programs imply deteriorating patient retention?. Am J Epidemiol 180(12):1208-12, 2014. e-Pub 2014. PMID: 25399412.
      482. Bohlius J, Valeri F, Maskew M, Prozesky H, Garone D, Sengayi M, Fox MP, Davies MA, Egger M. Kaposi's Sarcoma in HIV-infected patients in South Africa: Multicohort study in the antiretroviral therapy era. Int J Cancer 135(11):2644-52, 2014. e-Pub 2014. PMID: 24729433.
      483. Gopal YN, Rizos H, Chen G, Deng W, Frederick DT, Cooper ZA, Scolyer RA, Pupo G, Komurov K, Sehgal V, Zhang J, Patel L, Pereira CG, Broom BM, Mills GB, Ram P, Smith PD, Wargo JA, Long GV, Davies MA. Inhibition of mTORC1/2 overcomes PGC1a and OxPhos-mediated resistance. Cancer Res 74(23):7037-47, 2014. e-Pub 2014. PMID: 25297634.
      484. Chen G, Chakravarti N, Aardalen K, Lazar AJ, Tetzlaff MT, Wubbenhorst B, Kim SB, Kopetz S, Ledoux AA, Gopal YN, Pereira CG, Deng W, Lee JS, Nathanson KL, Aldape KD, Prieto VG, Stuart D, Davies MA. Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target. Clin Cancer Res 20(21):5537-46, 2014. e-Pub 2014. PMID: 24803579.
      485. Bucheit AD, Chen G, Siroy A, Tetzlaff M, Broaddus R, Milton D, Fox P, Bassett R, Hwu P, Gershenwald JE, Lazar AJ, Davies MA. Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations. Clin Cancer Res 20(21):5527-36, 2014. e-Pub 2014. PMID: 25165098.
      486. Salazar-Vizcaya L, Keiser O, Karl Technau, Davies MA, Haas AD, Blaser N, Cox V, Eley B, Rabie H, Moultrie H, Giddy J, Wood R, Egger M, Estill J. Viral load versus CD4(+) monitoring and 5-year outcomes of antiretroviral therapy in HIV-positive children in Southern Africa: a cohort-based modelling study. AIDS 28(16):2451-60, 2014. e-Pub 2014. PMID: 25392857.
      487. Davies MA, Terhorst L, Nakonechny AJ, Skukla N, El Saadawi G. The development and effectiveness of a health information website designed to improve parents' self-efficacy in managing risk for obesity in preschoolers. J Spec Pediatr Nurs 19(4):316-30, 2014. e-Pub 2014. PMID: 25160030.
      488. Ford N, Stinson K, Davies MA, Cox V, Patten G, Cragg C, Van Cutsem G, Boulle A. Is it safe to drop CD4+ monitoring among virologically suppressed patients: a cohort evaluation from Khayelitsha, South Africa. AIDS 28(14):2003-5, 2014. e-Pub 2014. PMID: 25102088.
      489. Watson IR, Li L, Cabeceiras PK, Mahdavi M, Gutschner T, Genovese G, Wang G, Fang Z, Tepper JM, Stemke-Hale K, Tsai KY, Davies MA, Mills GB, Chin L. The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF. Cancer Res 74(17):4845-4852, 2014. e-Pub 2014. PMID: 25056119.
      490. Kugel CH, Hartsough EJ, Davies MA, Setiady YY, Aplin AE. Function-Blocking ERBB3 Antibody Inhibits the Adaptive Response to RAF Inhibitor. Cancer Res 74(15):4122-32, 2014. e-Pub 2014. PMID: 25035390.
      491. Alrwas A, Papadopoulos NE, Cain S, Patel SP, Kim KB, Deburr TL, Bassett R, Hwu WJ, Bedikian AY, Davies MA, Woodman SE, Hwu P. Phase I trial of biochemotherapy with cisplatin, temozolomide, and dose escalation of nab-paclitaxel combined with interleukin-2 and interferon-α in patients with metastatic melanoma. Melanoma Res 24(4):342-8, 2014. e-Pub 2014. PMID: 24743052.
      492. Davies MA, May M, Bolton-Moore C, Chimbetete C, Eley B, Garone D, Giddy J, Moultrie H, Ndirangu J, Phiri S, Rabie H, Technau KG, Wood R, Boulle A, Egger M, Keiser O. Prognosis of children with HIV-1 infection starting antiretroviral therapy in Southern Africa: a collaborative analysis of treatment programs. Pediatr Infect Dis J 33(6):608-16, 2014. e-Pub 2014. PMID: 24378936.
      493. Technau KG, Schomaker M, Kuhn L, Moultrie H, Coovadia A, Eley B, Rabie H, Wood R, Cox V, Vizcaya LS, Muchiri E, Davies MA. Virologic response in children treated with abacavir-compared with stavudine-based antiretroviral treatment: a South African multi-cohort analysis. Pediatr Infect Dis J 33(6):617-22, 2014. e-Pub 2014. PMID: 24378944.
      494. Dutton-Regester K, Gartner JJ, Emmanuel R, Qutob N, Davies MA, Gershenwald JE, Robinson W, Robinson S, Rosenberg SA, Scolyer RA, Mann GJ, Thompson JF, Hayward NK, Samuels Y. A highly recurrent RPS27 5'UTR mutation in melanoma. Oncotarget 5(10):2912-7, 2014. e-Pub 2014. PMID: 24913145.
      495. Davies MA, Kalk E. Provider-initiated HIV testing and counselling for children. PLoS Med 11(5):e1001650, 2014. e-Pub 2014. PMID: 24866364.
      496. Mulenga L, Musonda P, Mwango A, Vinikoor MJ, Davies MA, Mweemba A, Calmy A, Stringer JS, Keiser O, Chi BH, Wandeler G. Effect of baseline renal function on tenofovir-containing antiretroviral therapy outcomes in Zambia. Clin Infect Dis 58(10):1473-80, 2014. e-Pub 2014. PMID: 24585558.
      497. Penazzato M, Davies MA, Apollo T, Negussie E, Ford N. Task shifting for the delivery of pediatric antiretroviral treatment: a systematic review. J Acquir Immune Defic Syndr 65(4):414-22, 2014. e-Pub 2014. PMID: 24583614.
      498. Ma XH, Piao SF, Dey S, McAfee Q, Karakousis G, Villanueva J, Hart LS, Levi S, Hu J, Zhang G, Lazova R, Klump V, Pawelek JM, Xu X, Xu W, Schuchter LM, Davies MA, Herlyn M, Winkler J, Koumenis C, Amaravadi RK. Targeting ER stress induced-autophagy overcomes resistance to BRAF inhibition in melanoma. J Clin Invest 124(3):1406-17, 2014. e-Pub 2014. PMID: 24569374.
      499. Lopez-Rivera E, Jayaraman P, Parikh F, Davies MA, Ekmekcioglu S, Izadmehr S, Milton DR, Chipuk JE, Grimm EA, Estrada Y, Aguirre-Ghiso J, Sikora AG. Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2. Cancer Res 74(4):1067-78, 2014. e-Pub 2014. PMID: 24398473.
      500. Prickett TD, Zerlanko B, Gartner JJ, Parker SC, Dutton-Regester K, Lin JC, Teer JK, Wei X, Jiang J, Sequencing Program NC, Chen G, Davies MA, Gershenwald JE, Robinson W, Robinson S, Hayward NK, Rosenberg SA, Margulies EH, Samuels Y. Somatic Mutations in MAP3K5 Attenuate Its Proapoptotic Function in Melanoma through Increased Binding to Thioredoxin. J Invest Dermatol 134(2):452-60, 2014. e-Pub 2014. PMID: 24008424.
      501. Avila D, Althoff KN, Mugglin C, Wools-Kaloustian K, Koller M, Dabis F, Nash D, Gsponer T, Sungkanuparph S, McGowan C, May M, Cooper D, Chimbetete C, Wolff M, Collier A, McManus H, Davies MA, Costagliola D, Crabtree-Ramirez B, Chaiwarith R, Cescon A, Cornell M, Diero L, Phanuphak P, Sawadogo A, Ehmer J, Eholie SP, Li PC, Fox MP, Gandhi NR, Gonzalez E, Lee CK, Hoffmann CJ, Kambugu A, Keiser O, Ditangco R, Prozesky H, Lampe F, Kumarasamy N, Kitahata M, Lugina E, Lyamuya R, Vonthanak S, Fink V, d'Arminio Monforte A, Luz PM, Chen YM, Minga A, Casabona J, Mwango A, Choi JY, Newell ML, Bukusi EA, Ngonyani K, Merati TP, Otieno J, Bosco MB, Phiri S, Ng OT, Anastos K, Rockstroh J, Santos I, Oka S, Somi G, Stephan C, Teira R, Wabwire D, Wandeler G, Boulle A, Reiss P, Wood R, Chi BH, Williams C, Sterne JA, Egger M. Immunodeficiency at the start of combination antiretroviral therapy in low-, middle-, and high-income countries. J Acquir Immune Defic Syndr 65(1):e8-16, 2014. e-Pub 2014. PMID: 24419071.
      502. Baladandayuthapani V, Talluri R, Ji Y, Coombes KR, Lu Y, Hennessy BT, Davies MA, Mallick BK. BAYESIAN SPARSE GRAPHICAL MODELS FOR CLASSIFICATION WITH APPLICATION TO PROTEIN EXPRESSION DATA. Ann Appl Stat 8(3):1443-1468, 2014. e-Pub 2014. PMID: 26246866.
      503. Curry JL, Davies MA, Calderone TL, Nathanson K, Prieto VG, Gershenwald JE. Tissue resources for clinical use and marker studies in melanoma. Methods Mol Biol 1102:679-95, 2014. e-Pub 2014. PMID: 24259006.
      504. Frederick DT, Salas Fragomeni RA, Schalck A, Ferreiro-Neira I, Hoff T, Cooper ZA, Haq R, Panka DJ, Kwong LN, Davies MA, Cusack JC, Flaherty KT, Fisher DE, Mier JW, Wargo JA, Sullivan RJ. Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics. PLoS One 9(7):e101286, 2014. e-Pub 2014. PMID: 24983357.
      505. Hayes AR, O'Sullivan AJ, Davies MA. A case of pituitary apoplexy in pregnancy. Endocrinol Diabetes Metab Case Rep 2014:140043, 2014. e-Pub 2014. PMID: 25031837.
      506. Green A, de Azevedo V, Patten G, Davies MA, Ibeto M, Cox V. Clinical mentorship of nurse initiated antiretroviral therapy in Khayelitsha, South Africa: a quality of care assessment. PLoS One 9(6):e98389, 2014. e-Pub 2014. PMID: 24887260.
      507. Labhardt ND, Keiser O, Sello M, Lejone TI, Pfeiffer K, Davies MA, Egger M, Ehmer J, Wandeler G. Outcomes of antiretroviral treatment programmes in rural Lesotho: health centres and hospitals compared. J Int AIDS Soc 16(1):18616, 2013. e-Pub 2013. PMID: 24267671.
      508. Bucheit AD, Syklawer E, Jakob JA, Bassett RL Jr, Curry JL, Gershenwald JE, Kim KB, Hwu P, Lazar AJ, Davies MA. Clinical characteristics and outcomes with specific BRAF and NRAS mutations in patients with metastatic melanoma. Cancer 119(21):3821-9, 2013. e-Pub 2013. PMID: 23922205.
      509. Schomaker M, Egger M, Ndirangu J, Phiri S, Moultrie H, Technau K, Cox V, Giddy J, Chimbetete C, Wood R, Gsponer T, Bolton Moore C, Rabie H, Eley B, Muhe L, Penazzato M, Essajee S, Keiser O, Davies MA. When to start antiretroviral therapy in children aged 2-5 years: a collaborative causal modelling analysis of cohort studies from southern Africa. PLoS Med 10(11):e1001555, 2013. e-Pub 2013. PMID: 24260029.
      510. Siegfried N, Davies MA, Penazzato M, Muhe LM, Egger M. Optimal time for initiating antiretroviral therapy (ART) in HIV-infected, treatment-naive children aged 2 to 5 years old. Cochrane Database Syst Rev 2013(10):CD010309, 2013. e-Pub 2013. PMID: 24114324.
      511. Wandeler G, Gsponer T, Mulenga L, Garone D, Wood R, Maskew M, Prozesky H, Hoffmann C, Ehmer J, Dickinson D, Davies MA, Egger M, Keiser O. Zidovudine impairs immunological recovery on first-line antiretroviral therapy: collaborative analysis of cohort studies in southern Africa. AIDS 27(14):2225-32, 2013. e-Pub 2013. PMID: 23660577.
      512. Nathanson KL, Martin AM, Wubbenhorst B, Greshock J, Letrero R, D'Andrea K, O'Day S, Infante JR, Falchook GS, Arkenau HT, Millward M, Brown MP, Pavlick A, Davies MA, Ma B, Gagnon R, Curtis M, Lebowitz PF, Kefford R, Long GV. Tumor genetic analyses of patients with metastatic melanoma treated with the BRAF inhibitor dabrafenib (GSK2118436). Clin Cancer Res 19(17):4868-78, 2013. e-Pub 2013. PMID: 23833299.
      513. Gartner JJ, Parker SC, Prickett TD, Dutton-Regester K, Stitzel ML, Lin JC, Davis S, Simhadri VL, Jha S, Katagiri N, Gotea V, Teer JK, Wei X, Morken MA, Bhanot UK, Chen G, Elnitski LL, Davies MA, Gershenwald JE, Carter H, Karchin R, Robinson W, Robinson S, Rosenberg SA, Collins FS, Parmigiani G, Komar AA, Kimchi-Sarfaty C, Hayward NK, Margulies EH, Samuels Y. Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma. Proc Natl Acad Sci U S A 110(33):13481-6, 2013. e-Pub 2013. PMID: 23901115.
      514. Technau KG, Lazarus E, Kuhn L, Abrams EJ, Sorour G, Strehlau R, Reubenson G, Davies MA, Coovadia A. Poor early virologic performance and durability of abacavir-based first-line regimens for HIV-infected children. Pediatr Infect Dis J 32(8):851-5, 2013. e-Pub 2013. PMID: 23860481.
      515. Greaves WO, Verma S, Patel KP, Davies MA, Barkoh BA, Galbincea JM, Yao H, Lazar AJ, Aldape KD, Medeiros LJ, Luthra R. Frequency and spectrum of BRAF mutations in a retrospective, single-institution study of 1112 cases of melanoma. J Mol Diagn 15(2):220-6, 2013. e-Pub 2013. PMID: 23273605.
      516. Patel SP, Lazar AJ, Papadopoulos NE, Liu P, Infante JR, Glass MR, Vaughn CS, LoRusso PM, Cohen RB, Davies MA, Kim KB. Clinical responses to selumetinib (AZD6244; ARRY-142886)-based combination therapy stratified by gene mutations in patients with metastatic melanoma. Cancer 119(4):799-805, 2013. e-Pub 2013. PMID: 22972589.
      517. Leroy V, Malateste K, Rabie H, Lumbiganon P, Ayaya S, Dicko F, Davies MA, Kariminia A, Wools-Kaloustian K, Aka E, Phiri S, Aurpibul L, Yiannoutsos C, Signate-Sy H, Mofenson L, Dabis F. Outcomes of antiretroviral therapy in children in Asia and Africa: a comparative analysis of the IeDEA pediatric multiregional collaboration. J Acquir Immune Defic Syndr 62(2):208-19, 2013. e-Pub 2013. PMID: 23187940.
      518. Mao M, Tian F, Mariadason JM, Tsao CC, Lemos R Jr, Dayyani F, Gopal YN, Jiang ZQ, Wistuba II, Tang XM, Bornman WG, Bollag G, Mills GB, Powis G, Desai J, Gallick GE, Davies MA, Kopetz S. Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents. Clin Cancer Res 19(3):657-67, 2013. e-Pub 2013. PMID: 23251002.
      519. Bokhari AR, Davies MA, Diamond T. Endoscopic transsphenoidal pituitary surgery: a single surgeon experience and the learning curve. Br J Neurosurg 27(1):44-9, 2013. e-Pub 2013. PMID: 22900510.
      520. Liu C, Peng W, Xu C, Lou Y, Zhang M, Wargo JA, Chen JQ, Li HS, Watowich SS, Yang Y, Tompers Frederick D, Cooper ZA, Mbofung RM, Whittington M, Flaherty KT, Woodman SE, Davies MA, Radvanyi LG, Overwijk WW, Lizee G, Hwu P. BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice. Clin Cancer Res 19(2):393-403, 2013. e-Pub 2013. PMID: 23204132.
      521. Davies MA, Phiri S, Wood R, Wellington M, Cox V, Bolton-Moore C, Timmerman V, Moultrie H, Ndirangu J, Rabie H, Technau K, Giddy J, Maxwell N, Boulle A, Keiser O, Egger M, Eley B. Temporal trends in the characteristics of children at antiretroviral therapy initiation in southern Africa: the IeDEA-SA Collaboration. PLoS One 8(12):e81037, 2013. e-Pub 2013. PMID: 24363808.
      522. Estill J, Egger M, Johnson LF, Gsponer T, Wandeler G, Davies MA, Boulle A, Wood R, Garone D, Stringer JS, Hallett TB, Keiser O. Monitoring of antiretroviral therapy and mortality in HIV programmes in Malawi, South Africa and Zambia: mathematical modelling study. PLoS One 8(2):e57611, 2013. e-Pub 2013. PMID: 23469035.
      523. Radvanyi LG, Bernatchez C, Zhang M, Fox PS, Miller P, Chacon J, Wu R, Lizee G, Mahoney S, Alvarado G, Glass M, Johnson VE, McMannis JD, Shpall E, Prieto V, Papadopoulos N, Kim K, Homsi J, Bedikian A, Hwu WJ, Patel S, Ross MI, Lee JE, Gershenwald JE, Lucci A, Royal R, Cormier JN, Davies MA, Mansaray R, Fulbright OJ, Toth C, Ramachandran R, Wardell S, Gonzalez A, Hwu P. Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients. Clin Cancer Res 18(24):6758-70, 2012. e-Pub 2012. PMID: 23032743.
      524. Davies MA, Boulle A, Technau K, Eley B, Moultrie H, Rabie H, Garone D, Giddy J, Wood R, Egger M, Keiser O. The role of targeted viral load testing in diagnosing virological failure in children on antiretroviral therapy with immunological failure. Trop Med Int Health 17(11):1386-90, 2012. e-Pub 2012. PMID: 22974345.
      525. Joseph RW, Eckel-Passow JE, Sharma R, Liu P, Parker A, Jakob J, Buchbinder E, Bassett RL, Davies MA, Hwu P, Atkins MB, Sullivan RJ. Characterizing the clinical benefit of ipilimumab in patients who progressed on high-dose IL-2. J Immunother 35(9):711-5, 2012. e-Pub 2012. PMID: 23090080.
      526. Long GV, Trefzer U, Davies MA, Kefford RF, Ascierto PA, Chapman PB, Puzanov I, Hauschild A, Robert C, Algazi A, Mortier L, Tawbi H, Wilhelm T, Zimmer L, Switzky J, Swann S, Martin AM, Guckert M, Goodman V, Streit M, Kirkwood JM, Schadendorf D. Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial. Lancet Oncol 13(11):1087-95, 2012. e-Pub 2012. PMID: 23051966.
      527. Beasley GM, Coleman AP, Raymond A, Sanders G, Selim MA, Peterson BL, Brady MS, Davies MA, Augustine C, Tyler DS. A phase I multi-institutional study of systemic sorafenib in conjunction with regional melphalan for in-transit melanoma of the extremity. Ann Surg Oncol 19(12):3896-3905, 2012. e-Pub 2012. PMID: 22549288.
      528. Khalili JS, Liu S, Rodriguez-Cruz TG, Whittington M, Wardell S, Liu C, Zhang M, Cooper ZA, Frederick DT, Li Y, Zhang M, Joseph RW, Bernatchez C, Ekmekcioglu S, Grimm E, Radvanyi LG, Davis RE, Davies MA, Wargo JA, Hwu P, Lizee G. Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma. Clin Cancer Res 18(19):5329-40, 2012. e-Pub 2012. PMID: 22850568.
      529. Gsponer T, Weigel R, Davies MA, Bolton C, Moultrie H, Vaz P, Rabie H, Technau K, Ndirangu J, Eley B, Garone D, Wellington M, Giddy J, Ehmer J, Egger M, Keiser O. Variability of growth in children starting antiretroviral treatment in southern Africa. Pediatrics 130(4):e966-77, 2012. e-Pub 2012. PMID: 22987878.
      530. Kim J, Lazar AJ, Davies MA, Homsi J, Papadopoulos NE, Hwu WJ, Bedikian AY, Woodman SE, Patel SP, Hwu P, Kim KB. BRAF, NRAS and KIT sequencing analysis of spindle cell melanoma. J Cutan Pathol 39(9):821-5, 2012. e-Pub 2012. PMID: 22809251.
      531. Khalili JS, Yu X, Wang J, Hayes BC, Davies MA, Lizee G, Esmaeli B, Woodman SE. Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner. Clin Cancer Res 18(16):4345-55, 2012. e-Pub 2012. PMID: 22733540.
      532. Jakob JA, Bassett RL Jr, Ng CS, Curry JL, Joseph RW, Alvarado GC, Rohlfs ML, Richard J, Gershenwald JE, Kim KB, Lazar AJ, Hwu P, Davies MA. NRAS mutation status is an independent prognostic factor in metastatic melanoma. Cancer 118(16):4014-23, 2012. e-Pub 2012. PMID: 22180178.
      533. Alvarado G, Noor R, Bassett R, Papadopoulos NE, Kim KB, Hwu WJ, Bedikian A, Patel S, Hwu P, Davies MA. Risk of intracranial hemorrhage with anticoagulation therapy in melanoma patients with brain metastases. Melanoma Res 22(4):310-5, 2012. e-Pub 2012. PMID: 22584956.
      534. Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K, Wagle N, Wargo J, Chong K, Morton DL, Stemke-Hale K, Chen G, Noble M, Meyerson M, Ladbury JE, Davies MA, Gershenwald JE, Wagner SN, Hoon DS, Schadendorf D, Lander ES, Gabriel SB, Getz G, Garraway LA, Chin L. A landscape of driver mutations in melanoma. Cell 150(2):251-63, 2012. e-Pub 2012. PMID: 22817889.
      535. Estill J, Aubriere C, Egger M, Johnson L, Wood R, Garone D, Gsponer T, Wandeler G, Boulle A, Davies MA, Hallett TB, Keiser O. Viral load monitoring of antiretroviral therapy, cohort viral load and HIV transmission in Southern Africa: a mathematical modelling analysis. AIDS 26(11):1403-13, 2012. e-Pub 2012. PMID: 22421243.
      536. Chattopadhyay C, Ellerhorst JA, Ekmekcioglu S, Greene VR, Davies MA, Grimm EA. Association of activated c-Met with NRAS-mutated human melanomas. Int J Cancer 131(2):E56-65, 2012. e-Pub 2012. PMID: 22020736.
      537. Hatiboglu MA, Kong LY, Wei J, Wang Y, McEnery KA, Fuller GN, Qiao W, Davies MA, Priebe W, Heimberger AB. The tumor microenvironment expression of p-STAT3 influences the efficacy of cyclophosphamide with WP1066 in murine melanoma models. Int J Cancer 131(1):8-17, 2012. e-Pub 2012. PMID: 21792892.
      538. Mu H, Calderone TL, Davies MA, Prieto VG, Wang H, Mills GB, Bar-Eli M, Gershenwald JE. Lysophosphatidic acid induces lymphangiogenesis and IL-8 production in vitro in human lymphatic endothelial cells. Am J Pathol 180(5):2170-81, 2012. e-Pub 2012. PMID: 22465753.
      539. Al-Zaid T, Ditelberg JS, Prieto VG, Lev D, Luthra R, Davies MA, Diwan AH, Wang WL, Lazar AJ. Trichilemmomas show loss of PTEN in Cowden syndrome but only rarely in sporadic tumors. J Cutan Pathol 39(5):493-9, 2012. e-Pub 2012. PMID: 22486434.
      540. Johnson LF, Davies MA, Moultrie H, Sherman GG, Bland RM, Rehle TM, Dorrington RE, Newell ML. The effect of early initiation of antiretroviral treatment in infants on pediatric AIDS mortality in South Africa: a model-based analysis. Pediatr Infect Dis J 31(5):474-80, 2012. e-Pub 2012. PMID: 22189531.
      541. Johnson LF, Stinson K, Newell ML, Bland RM, Moultrie H, Davies MA, Rehle TM, Dorrington RE, Sherman GG. The contribution of maternal HIV seroconversion during late pregnancy and breastfeeding to mother-to-child transmission of HIV. J Acquir Immune Defic Syndr 59(4):417-25, 2012. e-Pub 2012. PMID: 22193774.
      542. Douis H, James SL, Grimer RJ, Davies MA. Is bone scintigraphy necessary in the initial surgical staging of chondrosarcoma of bone?. Skeletal Radiol 41(4):429-36, 2012. e-Pub 2012. PMID: 21892729.
      543. Deng W, Gopal YN, Scott A, Chen G, Woodman SE, Davies MA. Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition. Pigment Cell Melanoma Res 25(2):248-58, 2012. e-Pub 2012. PMID: 22171948.
      544. Davies MA, Fox PS, Papadopoulos NE, Bedikian AY, Hwu WJ, Lazar AJ, Prieto VG, Culotta KS, Madden TL, Xu Q, Huang S, Deng W, Ng CS, Gupta S, Liu W, Dancey JE, Wright JJ, Bassett RL, Hwu P, Kim KB. Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma. Clin Cancer Res 18(4):1120-8, 2012. e-Pub 2012. PMID: 22223528.
      545. Springer BD, Habet NA, Griffin WL, Nanson CJ, Davies MA. Deformation of 1-piece metal acetabular components. J Arthroplasty 27(1):48-54, 2012. e-Pub 2012. PMID: 21641760.
      546. Joseph RW, Sullivan RJ, Harrell R, Stemke-Hale K, Panka D, Manoukian G, Percy A, Bassett RL, Ng CS, Radvanyi L, Hwu P, Atkins MB, Davies MA. Correlation of NRAS mutations with clinical response to high-dose IL-2 in patients with advanced melanoma. J Immunother 35(1):66-72, 2012. e-Pub 2012. PMID: 22130161.
      547. Davies MA. Regulation, role, and targeting of Akt in cancer. J Clin Oncol 29(35):4715-7, 2011. e-Pub 2011. PMID: 22025159.
      548. Davies MA, Boulle A, Eley B, Moultrie H, Technau K, Rabie H, van Cutsem G, Giddy J, Wood R, Egger M, Keiser O. Accuracy of immunological criteria for identifying virological failure in children on antiretroviral therapy - the IeDEA Southern Africa Collaboration. Trop Med Int Health 16(11):1367-71, 2011. e-Pub 2011. PMID: 21834797.
      549. Prickett TD, Wei X, Cardenas-Navia I, Teer JK, Lin JC, Walia V, Gartner J, Jiang J, Cherukuri PF, Molinolo A, Davies MA, Gershenwald JE, Stemke-Hale K, Rosenberg SA, Margulies EH, Samuels Y. Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma. Nat Genet 43(11):1119-26, 2011. e-Pub 2011. PMID: 21946352.
      550. Wei X, Walia V, Lin JC, Teer JK, Prickett TD, Gartner J, Davis S, Stemke-Hale K, Davies MA, Gershenwald JE, Robinson W, Robinson S, Rosenberg SA, Samuels Y. Exome sequencing identifies GRIN2A as frequently mutated in melanoma. Nat Genet 43(5):442-6, 2011. e-Pub 2011. PMID: 21499247.
      551. Davies MA, Liu P, McIntyre S, Kim KB, Papadopoulos N, Hwu WJ, Hwu P, Bedikian A. Prognostic factors for survival in melanoma patients with brain metastases. Cancer 117(8):1687-96, 2011. e-Pub 2011. PMID: 20960525.
      552. Davies MA, Moultrie H, Eley B, Rabie H, Van Cutsem G, Giddy J, Wood R, Technau K, Keiser O, Egger M, Boulle A. Virologic failure and second-line antiretroviral therapy in children in South Africa--the IeDEA Southern Africa collaboration. J Acquir Immune Defic Syndr 56(3):270-8, 2011. e-Pub 2011. PMID: 21107266.
      553. Davies MA, Conley Y, Roth BL. Functional SNPs in genes encoding the 5-HT2A receptor modify the affinity and potency of several atypical antipsychotic drugs. Biol Res Nurs 13(1):55-60, 2011. e-Pub 2011. PMID: 20097665.
      554. Hennessy BT, Lu Y, Gonzalez-Angulo AM, Carey MS, Myhre S, Ju Z, Davies MA, Liu W, Coombes K, Meric-Bernstam F, Bedrosian I, McGahren M, Agarwal R, Zhang F, Overgaard J, Alsner J, Neve RM, Kuo WL, Gray JW, Borresen-Dale AL, Mills GB. A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers. Clin Proteomics 6(4):129-51, 2010. e-Pub 2010. PMID: 21691416.
      555. Gopal YN, Deng W, Woodman SE, Komurov K, Ram P, Smith PD, Davies MA. Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells. Cancer Res 70(21):8736-47, 2010. e-Pub 2010. PMID: 20959481.
      556. Wei X, Prickett TD, Viloria CG, Molinolo A, Lin JC, Cardenas-Navia I, Cruz P, Rosenberg SA, Davies MA, Gershenwald JE, Lopez-Otin C, Samuels Y. Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma. Mol Cancer Res 8(11):1513-25, 2010. e-Pub 2010. PMID: 21047771.
      557. Griffin WL, Nanson CJ, Springer BD, Davies MA, Fehring TK. Reduced articular surface of one-piece cups: a cause of runaway wear and early failure. Clin Orthop Relat Res 468(9):2328-32, 2010. e-Pub 2010. PMID: 20480405.
      558. Fenner L, Brinkhof MW, Keiser O, Weigel R, Cornell M, Moultrie H, Prozesky H, Technau K, Eley B, Vaz P, Pascoe M, Giddy J, Van Cutsem G, Wood R, Egger M, Davies MA. Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa. J Acquir Immune Defic Syndr 54(5):524-32, 2010. e-Pub 2010. PMID: 20588185.
      559. Altman MK, Gopal V, Jia W, Yu S, Hall H, Mills GB, McGinnis AC, Bartlett MG, Jiang G, Madan D, Prestwich GD, Xu Y, Davies MA, Murph MM. Targeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid. Mol Cancer 9:140, 2010. e-Pub 2010. PMID: 20529378.
      560. Gray D, Nuttall J, Lombard C, Davies MA, Workman L, Apolles P, Eley B, Cotton M, Zar HJ. Low rates of hepatotoxicity in HIV-infected children on anti-retroviral therapy with and without isoniazid prophylaxis. J Trop Pediatr 56(3):159-65, 2010. e-Pub 2010. PMID: 19710246.
      561. Connell TG, Davies MA, Johannisen C, Wood K, Pienaar S, Wilkinson KA, Wilkinson RJ, Zar HJ, Beatty D, Nicol MP, Curtis N, Eley B. Reversion and conversion of Mycobacterium tuberculosis IFN-gamma ELISpot results during anti-tuberculous treatment in HIV-infected children. BMC Infect Dis 10:138, 2010. e-Pub 2010. PMID: 20507549.
      562. Davies MA, Conley Y, Puskar K. Incorporating evidence from pharmacologic and pharmacogenetic studies of atypical antipsychotic drugs into advanced psychiatric nursing practice. Perspect Psychiatr Care 46(2):98-107, 2010. e-Pub 2010. PMID: 20377797.
      563. Ding Z, Liang J, Li J, Lu Y, Ariyaratna V, Lu Z, Davies MA, Westwick JK, Mills GB. Physical association of PDK1 with AKT1 is sufficient for pathway activation independent of membrane localization and phosphatidylinositol 3 kinase. PLoS One 5(3):e9910, 2010. e-Pub 2010. PMID: 20361045.
      564. Sikora AG, Gelbard A, Davies MA, Sano D, Ekmekcioglu S, Kwon J, Hailemichael Y, Jayaraman P, Myers JN, Grimm EA, Overwijk WW. Targeted inhibition of inducible nitric oxide synthase inhibits growth of human melanoma in vivo and synergizes with chemotherapy. Clin Cancer Res 16(6):1834-44, 2010. e-Pub 2010. PMID: 20215556.
      565. Park ES, Rabinovsky R, Carey M, Hennessy BT, Agarwal R, Liu W, Ju Z, Deng W, Lu Y, Woo HG, Kim SB, Cheong JH, Garraway LA, Weinstein JN, Mills GB, Lee JS, Davies MA. Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set. Mol Cancer Ther 9(2):257-67, 2010. e-Pub 2010. PMID: 20124458.
      566. Davies MA, Stemke-Hale K, Lin E, Tellez C, Deng W, Gopal YN, Woodman SE, Calderone TC, Ju Z, Lazar AJ, Prieto VG, Aldape K, Mills GB, Gershenwald JE. Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma. Clin Cancer Res 15(24):7538-7546, 2009. e-Pub 2009. PMID: 19996208.
      567. Davies MA, Egger M, Keiser O, Boulle A. Paediatric antiretroviral treatment programmes in sub-Saharan Africa: a review of published clinical studies. Afr J AIDS Res 8(3):329-338, 2009. e-Pub 2009. PMID: 21124759.
      568. Davies MA, Keiser O, Technau K, Eley B, Rabie H, van Cutsem G, Giddy J, Wood R, Boulle A, Egger M, Moultrie H. Outcomes of the South African National Antiretroviral Treatment Programme for children: the IeDEA Southern Africa collaboration. S Afr Med J 99(10):730-7, 2009. e-Pub 2009. PMID: 20128272.
      569. Davies MA, Meintjes G. Assessing the contribution of the immune reconstitution inflammatory syndrome to mortality in developing country antiretroviral therapy programs. Clin Infect Dis 49(6):973-5, 2009. e-Pub 2009. PMID: 19673616.
      570. Cornell M, Technau K, Fairall L, Wood R, Moultrie H, van Cutsem G, Giddy J, Mohapi L, Eley B, MacPhail P, Prozesky H, Rabie H, Davies MA, Maxwell N, Boulle A. Monitoring the South African National Antiretroviral Treatment Programme, 2003-2007: the IeDEA Southern Africa collaboration. S Afr Med J 99(9):653-60, 2009. e-Pub 2009. PMID: 20073292.
      571. Sajatovic M, Davies MA, Ganocy SJ, Bauer MS, Cassidy KA, Hays RW, Safavi R, Blow FC, Calabrese JR. A comparison of the life goals program and treatment as usual for individuals with bipolar disorder. Psychiatr Serv 60(9):1182-9, 2009. e-Pub 2009. PMID: 19723732.
      572. Woodman SE, Trent JC, Stemke-Hale K, Lazar AJ, Pricl S, Pavan GM, Fermeglia M, Gopal YN, Yang D, Podoloff DA, Ivan D, Kim KB, Papadopoulos N, Hwu P, Mills GB, Davies MA. Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates. Mol Cancer Ther 8(8):2079-85, 2009. e-Pub 2009. PMID: 19671763.
      573. Vasudevan KM, Barbie DA, Davies MA, Rabinovsky R, McNear CJ, Kim JJ, Hennessy BT, Tseng H, Pochanard P, Kim SY, Dunn IF, Schinzel AC, Sandy P, Hoersch S, Sheng Q, Gupta PB, Boehm JS, Reiling JH, Silver S, Lu Y, Stemke-Hale K, Dutta B, Joy C, Sahin AA, Gonzalez-Angulo AM, Lluch A, Rameh LE, Jacks T, Root DE, Lander ES, Mills GB, Hahn WC, Sellers WR, Garraway LA. AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer. Cancer Cell 16(1):21-32, 2009. e-Pub 2009. PMID: 19573809.
      574. Davies MA, Connell T, Johannisen C, Wood K, Pienaar S, Wilkinson KA, Wilkinson RJ, Zar HJ, Eley B, Beatty D, Curtis N, Nicol MP. Detection of tuberculosis in HIV-infected children using an enzyme-linked immunospot assay. AIDS 23(8):961-969, 2009. e-Pub 2009. PMID: 19287300.
      575. O'Reilly KE, Warycha M, Davies MA, Rodrik V, Zhou XK, Yee H, Polsky D, Pavlick AC, Rosen N, Bhardwaj N, Mills G, Osman I. Phosphorylated 4E-BP1 is associated with poor survival in melanoma. Clin Cancer Res 15(8):2872-8, 2009. e-Pub 2009. PMID: 19336517.
      576. Nicol MP, Davies MA, Wood K, Hatherill M, Workman L, Hawkridge A, Eley B, Wilkinson KA, Wilkinson RJ, Hanekom WA, Beatty D, Hussey G. Comparison of T-SPOT.TB assay and tuberculin skin test for the evaluation of young children at high risk for tuberculosis in a community setting. Pediatrics 123(1):38-43, 2009. e-Pub 2009. PMID: 19117858.
      577. Nuttall JJ, Davies MA, Hussey GD, Eley BS. Bacillus Calmette-Guerin (BCG) vaccine-induced complications in children treated with highly active antiretroviral therapy. Int J Infect Dis 12(6):e99-105, 2008. e-Pub 2008. PMID: 18799339.
      578. Davies MA, Stemke-Hale K, Tellez C, Calderone TL, Deng W, Prieto VG, Lazar AJ, Gershenwald JE, Mills GB. A novel AKT3 mutation in melanoma tumours and cell lines. Br J Cancer 99(8):1265-8, 2008. e-Pub 2008. PMID: 18813315.
      579. Davies MA, McBride L, Sajatovic M. The collaborative care practice model in the long-term care of individuals with bipolar disorder: a case study. J Psychiatr Ment Health Nurs 15(8):649-53, 2008. e-Pub 2008. PMID: 18803739.
      580. Davies MA, Boulle A, Fakir T, Nuttall J, Eley B. Adherence to antiretroviral therapy in young children in Cape Town, South Africa, measured by medication return and caregiver self-report: a prospective cohort study. BMC Pediatr 8:34, 2008. e-Pub 2008. PMID: 18771599.
      581. Eley B, Davies MA, Apolles P, Cowburn C, Buys H, Zampoli M, Finlayson H, King S, Nuttall J. Antiretroviral treatment for children. S Afr Med J 96(9 Pt 2):988-93, 2006. e-Pub 2006. PMID: 17077930.
      582. Davies MA, Bryant SC, Larsen SP, Murrey DB, Nussman DS, Laxer EB, Darden BV. Comparison of cervical disk implants and cervical disk fusion treatments in human cadaveric models. J Biomech Eng 128(4):481-6, 2006. e-Pub 2006. PMID: 16813439.
      583. Davies MA, Spence Laschinger HK, Andrusyszyn MA. Clinical educators' empowerment, job tension, and job satisfaction: A test of Kanter's Theory. J Nurses Staff Dev 22(2):78-86, 2006. e-Pub 2006. PMID: 16603905.
      584. Davies MA, Setola V, Strachan RT, Sheffler DJ, Salay E, Hufeisen SJ, Roth BL. Pharmacologic analysis of non-synonymous coding h5-HT2A SNPs reveals alterations in atypical antipsychotic and agonist efficacies. Pharmacogenomics J 6(1):42-51, 2006. e-Pub 2006. PMID: 16314884.
      585. Laxer EB, Darden BV, Murrey DB, Milam RA, Rhyne AL, Claytor B, Nussman DS, Powers TW, Davies MA, Bryant SC, Larsen SP, Bhatt M, Brodziak J, Polic J. Adjacent segment disc pressures following two-level cervical disc replacement versus simulated anterior cervical fusion. Stud Health Technol Inform 123:488-92, 2006. e-Pub 2006. PMID: 17108473.
      586. Davies MA, Compton-Toth BA, Hufeisen SJ, Meltzer HY, Roth BL. The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: is M1 agonism a pre-requisite for mimicking clozapine's actions?. Psychopharmacology (Berl) 178(4):451-60, 2005. e-Pub 2005. PMID: 15765260.
      587. Davies MA, Tales H. Enhancing patient safety through a standardized model of physiologic monitoring. Healthc Q 8 Spec No:49-52, 2005. e-Pub 2005. PMID: 16334072.
      588. Cordato DJ, Davies MA, Masters LT, Cremer PD, Schwartz RS, Sorby W, Becvarovski Z. Positional vomiting due to a thoracic spinal dural arteriovenous fistula. Case report. J Neurosurg Spine 1(2):219-22, 2004. e-Pub 2004. PMID: 15347009.
      589. Eley B, Nuttall J, Davies MA, Smith L, Cowburn C, Buys H, Hussey G. Initial experience of a public sector antiretroviral treatment programme for HIV-infected children and their infected parents. S Afr Med J 94(8):643-6, 2004. e-Pub 2004. PMID: 15352588.
      590. Hunter PR, Bickerstaff K, Davies MA. Potential sources of bias in the use of individual's recall of the frequency of exposure to air pollution for use in exposure assessment in epidemiological studies: a cross-sectional survey. Environ Health 3(1):3, 2004. e-Pub 2004. PMID: 15056391.
      591. Hunter PR, Davies MA, Hill H, Whittaker M, Sufi F. The prevalence of self-reported symptoms of respiratory disease and community belief about the severity of pollution from various sources. Int J Environ Health Res 13(3):227-38, 2003. e-Pub 2003. PMID: 12909554.
      592. Calabrese JR, Hirschfeld RM, Reed M, Davies MA, Frye MA, Keck PE, Lewis L, McElroy SL, McNulty JP, Wagner KD. Impact of bipolar disorder on a U.S. community sample. J Clin Psychiatry 64(4):425-32, 2003. e-Pub 2003. PMID: 12716245.
      593. Hirschfeld RM, Calabrese JR, Weissman MM, Reed M, Davies MA, Frye MA, Keck PE Jr, Lewis L, McElroy SL, McNulty JP, Wagner KD. Screening for bipolar disorder in the community. J Clin Psychiatry 64(1):53-9, 2003. e-Pub 2003. PMID: 12590624.
      594. Davies MA, Kim SJ, Parikh NU, Dong Z, Bucana CD, Gallick GE. Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells. Clin Cancer Res 8(6):1904-14, 2002. e-Pub 2002. PMID: 12060635.
      595. Koul D, Jasser SA, Lu Y, Davies MA, Shen R, Shi Y, Mills GB, Yung WK. Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity. Oncogene 21(15):2357-64, 2002. e-Pub 2002. PMID: 11948419.
      596. Beresford SA, Davies MA, Gallick GE, Donato NJ. Differential effects of phosphatidylinositol-3/Akt-kinase inhibition on apoptotic sensitization to cytokines in LNCaP and PCc-3 prostate cancer cells. J Interferon Cytokine Res 21(5):313-22, 2001. e-Pub 2001. PMID: 11429162.
      597. Tanaka M, Koul D, Davies MA, Liebert M, Steck PA, Grossman HB. MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells. Oncogene 19(47):5406-12, 2000. e-Pub 2000. PMID: 11103942.
      598. Lu Y, Lin YZ, LaPushin R, Cuevas B, Fang X, Yu SX, Davies MA, Khan H, Furui T, Mao M, Zinner R, Hung MC, Steck P, Siminovitch K, Mills GB. The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells. Oncogene 18(50):7034-45, 1999. e-Pub 1999. PMID: 10597304.
      599. Davies MA, Koul D, Dhesi H, Berman R, McDonnell TJ, McConkey D, Yung WK, Steck PA. Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN. Cancer Res 59(11):2551-6, 1999. e-Pub 1999. PMID: 10363971.
      600. Davies MA, Lu Y, Sano T, Fang X, Tang P, LaPushin R, Koul D, Bookstein R, Stokoe D, Yung WK, Mills GB, Steck PA. Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis. Cancer Res 58(23):5285-90, 1998. e-Pub 1998. PMID: 9850049.
      601. Davies MA, Ter Brugge K, Willinsky R, Wallace MC. The natural history and management of intracranial dural arteriovenous fistulae. Part 2: aggressive lesions. Interv Neuroradiol 3(4):303-11, 1997. e-Pub 1997. PMID: 20678361.
      602. Davies MA, Saleh J, Ter Brugge K, Willinsky R, Wallace MC. The natural history and management of intracranial dural arteriovenous fistulae. Part 1: benign lesions. Interv Neuroradiol 3(4):295-302, 1997. e-Pub 1997. PMID: 20678360.
      603. Milross CG, Davies MA, Fisher R, Mameghan J, Mameghan H. The efficacy of treatment for malignant epidural spinal cord compression. Australas Radiol 41(2):137-42, 1997. e-Pub 1997. PMID: 9153809.
      604. Davies MA, TerBrugge K, Willinsky R, Coyne T, Saleh J, Wallace MC. The validity of classification for the clinical presentation of intracranial dural arteriovenous fistulas. J Neurosurg 85(5):830-7, 1996. e-Pub 1996. PMID: 8893721.
      605. Davies MA, Turner J, Bentivoglio P. Spinal and basilar extraparenchymal neurocysticercosis. J Clin Neurosci 3(2):174-7, 1996. e-Pub 1996. PMID: 18638863.
      606. Davies MA, Pell MF, Brew BJ. Stereotactic biopsy of cerebral lesions in acquired immunodeficiency syndrome. J Clin Neurosci 2(1):40-4, 1995. e-Pub 1995. PMID: 18638782.
      607. Meltzer HY, Cola P, Way L, Thompson PA, Bastani B, Davies MA, Snitz B. Cost effectiveness of clozapine in neuroleptic-resistant schizophrenia. Am J Psychiatry 150(11):1630-8, 1993. e-Pub 1993. PMID: 8105705.
      608. Matheson JM, Truskett P, Davies MA, Vonau M. Hemispherectomy: a further modification using omentum vascularized free flaps. Aust N Z J Surg 63(8):646-50, 1993. e-Pub 1993. PMID: 8338485.
      609. Davies MA, Moon FC. 3-D spatial chaos in the elastica and the spinning top: Kirchhoff analogy. Chaos 3(1):93-99, 1993. e-Pub 1993. PMID: 12780018.
      610. Davies MA, Hubner W, Blume A, Mendelsohn R. Acyl chain conformational ordering in 1,2 dipalmitoylphosphatidylethanolamine. Integration of FT-IR and 2H NMR results. Biophys J 63(4):1059-62, 1992. e-Pub 1992. PMID: 1420924.
      611. Kahn EM, Munetz MR, Davies MA, Schulz SC. Akathisia: clinical phenomenology and relationship to tardive dyskinesia. Compr Psychiatry 33(4):233-6, 1992. e-Pub 1992. PMID: 1353716.
      612. Davies MA, Vonau M, Blum PW, Kwok BC, Matheson JM, Stening WA. Results of ulnar neuropathy at the elbow treated by decompression or anterior transposition. Aust N Z J Surg 61(12):929-34, 1991. e-Pub 1991. PMID: 1661575.
      613. Mendelsohn R, Davies MA, Schuster HF, Xu ZC, Bittman R. CD2 rocking modes as quantitative infrared probes of one-, two-, and three-bond conformational disorder in dipalmitoylphosphatidylcholine and dipalmitoylphosphatidylcholine/cholesterol mixtures. Biochemistry 30(35):8558-63, 1991. e-Pub 1991. PMID: 1888722.
      614. Davies MA, Conley RR, Schulz SC, Bell-Delaney J. One-year follow-up of 24 patients in a clinical trial of clozapine. Hosp Community Psychiatry 42(6):628-9, 1991. e-Pub 1991. PMID: 1864575.
      615. Davies MA, Schuster HF, Brauner JW, Mendelsohn R. Effects of cholesterol on conformational disorder in dipalmitoylphosphatidylcholine bilayers. A quantitative IR study of the depth dependence. Biochemistry 29(18):4368-73, 1990. e-Pub 1990. PMID: 2350543.
      616. Davies MA, Brauner JW, Schuster HF, Mendelsohn R. A quantitative infrared determination of acyl chain conformation in gramicidin/dipalmitoylphosphatidylcholine mixtures. Biochem Biophys Res Commun 168(1):85-90, 1990. e-Pub 1990. PMID: 1691641.
      617. Mendelsohn R, Davies MA, Brauner JW, Schuster HF, Dluhy RA. Quantitative determination of conformational disorder in the acyl chains of phospholipid bilayers by infrared spectroscopy. Biochemistry 28(22):8934-9, 1989. e-Pub 1989. PMID: 2605234.
      618. Davies MA, Bromet EJ, Schulz SC, Dunn LO, Morgenstern M. Community adjustment of chronic schizophrenic patients in urban and rural settings. Hosp Community Psychiatry 40(8):824-30, 1989. e-Pub 1989. PMID: 2759573.
      619. Davies MA, Munetz MR, Schulz SC, Bromet EJ. Assessing mental illness in SRO shelter residents. Hosp Community Psychiatry 38(10):1114-6, 1987. e-Pub 1987. PMID: 3666704.
      620. Chantler JK, Davies MA. The effect of antibody on rubella virus infection in human lymphoid cells. J Gen Virol 68 ( Pt 5):1277-88, 1987. e-Pub 1987. PMID: 3572365.
      621. Traber J, Davies MA, Dompert WU, Glaser T, Schuurman T, Seidel PR. Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821. Brain Res Bull 12(6):741-4, 1984. e-Pub 1984. PMID: 6541079.
      622. Noble J, Jones AG, Davies MA, Sledge CB, Kramer RI, Livni E. Leakage of radioactive particle systems from a synovial joint studied with a gamma camera. Its application to radiation synovectomy. J Bone Joint Surg Am 65(3):381-9, 1983. e-Pub 1983. PMID: 6826601.
      623. Kyes JJ, Davies MA. Pseudocommunication is the nurse-patient game. Nurs Life 2(1):50-54, 1982. e-Pub 1982. PMID: 6976538.
      624. Davies MA. Postsynaptic pharmacology of psychoactive substances in Aplysia californica. Brain Res Bull 6(6):495-502, 1981. e-Pub 1981. PMID: 6113882.
      625. Davies MA. Continuing care unit: a model of services for chronic psychiatric patients. J Psychiatr Nurs Ment Health Serv 19(2):42-5, 1981. e-Pub 1981. PMID: 6259346.
      626. Hipp FX, Gielen W, Davies MA, Hinzen DH. Blocking action of intracellularly injected neuraminidase on central synapses in vivo. Pflugers Arch 385(1):45-50, 1980. e-Pub 1980. PMID: 6251424.
      627. Davies MA, Hinzen DH. Is there an intracellular presynaptic effect of curare on neurotransmission?. Brain Res 169(1):199-207, 1979. e-Pub 1979. PMID: 222397.
      628. Davies MA, Hinzen DH. Is there a presynaptic action of curare on chemical transmission? [proceedings]. J Physiol 287:29P-30P, 1979. e-Pub 1979. PMID: 219183.
      629. Hinzen DH, Davies MA. Synaptic connexions and related postsynaptic pharmacology studied in the cerebral ganglion of Aplysia. Brain Res 144(1):49-62, 1978. e-Pub 1978. PMID: 25121.
      630. Davies MA, Gale J, Clarke WD. Audiotape and booklet self-instructional materials in physiology: an evaluation of their effectiveness and acceptability in the pre-clinical curriculum. Med Educ 11(6):370-3, 1977. e-Pub 1977. PMID: 74008.
      631. Davies MA, Hinzen DH. Synaptic properties of identified neurones in the cerebral ganglion of Aplysia [proceedings]. J Physiol 263(2):244P-245P, 1976. e-Pub 1976. PMID: 1018241.
      632. Bergner-Rabinowitz S, Ofek I, Davies MA, Rabinowitz K. Type-specific streptococcal antibodies in pyodermal nephritis. J Infect Dis 124(5):488-93, 1971. e-Pub 1971. PMID: 5115672.
      633. Davies HE, Davies MA, Gould CT. Sodium content of rat renal medulla during water diuresis. J Physiol 213(2):72P-73P, 1971. e-Pub 1971. PMID: 5574870.
      634. Freundlich E, Sterk VV, Hampel N, Davies MA. [Infant mortality in Western Galilee]. Harefuah 78(3):109-12, 1970. e-Pub 1970. PMID: 5535697.
      635. COLTER JS, DAVIES MA, CAMPBELL JB. STUDIES OF THREE VARIANTS OF MENGO ENCEPHALOMYELITIS VIRUS. II. INHIBITION OF INTERACTION WITH L CELLS BY AN AGAR INHIBITOR AND BY PROTAMINE. Virology 24:578-85, 1964. e-Pub 1964. PMID: 14240405.
      636. COLTER JS, DAVIES MA, CAMPBELL JB. STUDIES OF THREE VARIANTS OF MENGO ENCEPHALOMYELITIS VIRUS. I. RATE OF ATTACHMENT TO L CELLS, AND EFFECT OF PH ON INFECTIVITY. Virology 24:474-80, 1964. e-Pub 1964. PMID: 14227050.

      Invited Articles

      1. Saberian C, Davies MA. Re-thinking therapeutic development for CNS metastatic disease. Exp Dermatol 31(1):74-81, 2022. e-Pub 2022. PMID: 34152638.
      2. Brastianos P, Davies MA, Margolin K, Yu HA. Modern Management of Central Nervous System Metastases in the Era of Targeted Therapy and Immune Oncology. Am Soc Clin Oncol Educ Book 39:e59-e69, 2019. e-Pub 2019. PMID: 31099629.
      3. Davies MA, Flaherty KT. Melanoma in 2017: Moving treatments earlier to move further forwards. Nat Rev Clin Oncol 15(2):75-76, 2018. e-Pub 2018. PMID: 29182162.
      4. Davies MA, Saiag P, Long GV. Primary medical therapy for BRAFV600E-mutant melanoma brain metastases—is this good enough?. The Lancet Oncology 18(9):1137-1284, 2017. e-Pub 2017.
      5. Glitza Oliva I, Tawbi H, Davies MA. Melanoma brain metastases: current areas of investigation and future directions. Cancer J 23(1):68-74, 2017. e-Pub 2017. PMID: 28114258.
      6. Loghavi S, Routbort MJ, Patel KP, Luthra R, Wang WL, Broaddus RR, Davies MA, Lazar AJ. How Do We Make Clinical Molecular Testing for Cancer Standard of Care for Pathology Departments?. J Natl Compr Canc Netw 14(6):787-92, 2016. e-Pub 2016. PMID: 27283170.
      7. Davies MA. Role and complexity of next-generation sequencing in melanoma. Cancer Cytopathol 123(6):329-30, 2015. e-Pub 2015. PMID: 25877344.
      8. McQuade J, Davies MA. Converting biology into clinical benefit: lessons learned from BRAF inhibitors. Melanoma Manag 2(3):241-254, 2015. e-Pub 2015. PMID: 26594316.

      Review Articles

      1. Hajjar J, Stephen B, Aaroe AE, Aiche MM, Al-Zubidi N, Ameri M, Aragon KE, Carabenciov ID, Chambers MS, Chaudhry AL, Connors JM, Davies MA, Debnath KC, Faiz SA, Fuller CD, Goepfert RP, Gombos DS, Gupta S, Hadfield M, Hutcheson KA, Islam S, Jalal A, Jayasekera M, Jazieh KA, Khine A, Kim P, Lai SY, Lei YL, Li YJ, Markovic SN, McMillan H, Moreno AC, Muhaj F, Nader ME, Otun A, Pacha O, Palaskas NL, Patel AB, Patel N, Quandt Z, Sagiv O, Sharon E, Shatila M, Sheshadri A, Suarez-Almazor ME, Thomas AS, Wang Y, Won A, Zhang HC, Naing A. The Immune Checkpoint Inhibitors Journey: From Early Promise to Lasting Impact. J Immunother Precis Oncol 9(4):153-245, 2026. e-Pub 2026. PMID: 42820064.
      2. Flaherty KT, Aplin AE, Davies MA, Hacohen N, Herlyn M, Hoon D, Hwu P, Lotem M, Mule J, Wargo JA, Fisher DE. Facts & Hopes: towards the next quantum leap in melanoma. Clin Cancer Res 31(14):2882-2889, 2025. e-Pub 2025. PMID: 40407722.
      3. Hasanov M, Acikgoz Y, Davies MA. Melanoma Brain Metastasis: Biology and Therapeutic Advances. Hematol Oncol Clin North Am 38(5):1027-1043, 2024. e-Pub 2024. PMID: 38845301.
      4. Hunter M, Peters S, Khumalo N, Davies MA. Analysis of patient flow and barriers to timely discharge from general medical wards at a tertiary academic hospital in Cape Town, South Africa. BMC Health Serv Res 24(1):287, 2024. e-Pub 2024. PMID: 38448938.
      5. Smalley I, Boire A, Brastianos P, Kluger HM, Hernando-Monge E, Forsyth PA, Ahmed KA, Smalley KSM, Ferguson S, Davies MA, Glitza Oliva IC. Leptomeningeal disease in melanoma: An update on the developments in pathophysiology and clinical care. Pigment Cell Melanoma Res 37(1):51-67, 2024. e-Pub 2023. PMID: 37622466.
      6. Karz A, Dimitrova M, Kleffman K, Alvarez-Breckenridge C, Atkins MB, Boire A, Bosenberg M, Brastianos P, Cahill DP, Chen Q, Ferguson S, Forsyth P, Glitza Oliva IC, Goldberg SB, Holmen SL, Knisely JPS, Merlino G, Nguyen DX, Pacold ME, Perez-Guijarro E, Smalley KSM, Tawbi HA, Wen PY, Davies MA, Kluger HM, Mehnert JM, Hernando E. Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities. Pigment Cell Melanoma Res 35(6):554-572, 2022. e-Pub 2022. PMID: 35912544.
      7. Maskew M, Technau K, Davies MA, Vreeman R, Fox MP. Adolescent retention in HIV care within differentiated service-delivery models in sub-Saharan Africa. Lancet HIV 9(10):e726-e734, 2022. e-Pub 2022. PMID: 36088915.
      8. Saberian C, Sperduto P, Davies MA. Targeted therapy strategies for melanoma brain metastasis. Neurooncol Adv 3(Suppl 5):v75-v85, 2021. e-Pub 2021. PMID: 34859235.
      9. Ambrosioni J, Blanco JL, Reyes-Uruena JM, Davies MA, Sued O, Marcos MA, Martinez E, Bertagnolio S, Alcami J, Miro JM. Overview of SARS-CoV-2 infection in adults living with HIV. Lancet HIV 8(5):e294-e305, 2021. e-Pub 2021. PMID: 33915101.
      10. Glitza IC, Smalley KSM, Brastianos PK, Davies MA, McCutcheon I, Liu JKC, Ahmed KA, Arrington JA, Evernden BR, Smalley I, Eroglu Z, Khushalani N, Margolin K, Kluger H, Atkins MB, Tawbi H, Boire A, Forsyth P. Leptomeningeal disease in melanoma patients: An update to treatment, challenges, and future directions. Pigment Cell Melanoma Res 33(4):527-541, 2020. e-Pub 2020. PMID: 31916400.
      11. Anderson K, Muloiwa R, Davies MA. Long-term outcomes in perinatally HIV-infected adolescents and young adults on antiretroviral therapy: a review of South African and global literature. Afr J AIDS Res 19(1):1-12, 2020. e-Pub 2020. PMID: 32122278.
      12. Gray DM, Davies MA, Githinji L, Levin M, Mapani M, Nowalaza Z, Washaya N, Yassin A, Zampoli M, Zar HJ, Vanker A. COVID-19 and Pediatric Lung Disease: A South African Tertiary Center Experience. Front Pediatr 8:614076, 2020. e-Pub 2020. PMID: 33553073.
      13. Stover J, Glaubius R, Mofenson L, Dugdale CM, Davies MA, Patten G, Yiannoutsos C. Updates to the Spectrum/AIM model for estimating key HIV indicators at national and subnational levels. AIDS 33 Suppl 3(Suppl 3):S227-S234, 2019. e-Pub 2019. PMID: 31805028.
      14. Dower A, Davies MA, Ghahreman A. Pathologic Basis of Lumbar Radicular Pain. World Neurosurg 128:114-121, 2019. e-Pub 2019. PMID: 31028982.
      15. Amaria RN, Menzies AM, Burton EM, Scolyer RA, Tetzlaff MT, Antdbacka R, Ariyan C, Bassett R, Carter B, Daud A, Faries M, Fecher LA, Flaherty KT, Gershenwald JE, Hamid O, Hong A, Kirkwood JM, Lo S, Margolin K, Messina J, Postow MA, Rizos H, Ross MI, Rozeman EA, Saw RPM, Sondak V, Sullivan RJ, Taube JM, Thompson JF, van de Wiel BA, Eggermont AM, Davies MA, Consortium members INM, Ascierto PA, Spillane AJ, van Akkooi ACJ, Wargo JA, Blank CU, Tawbi HA, Long GV. Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium. Lancet Oncol 20(7):e378-e389, 2019. e-Pub 2019. PMID: 31267972.
      16. Judd A, Davies MA. Adolescent transition among young people with perinatal HIV in high-income and low-income settings. Curr Opin HIV AIDS 13(3):236-248, 2018. e-Pub 2018. PMID: 29528851.
      17. Fischer GM, Vashisht Gopal YN, McQuade JL, Peng W, DeBerardinis RJ, Davies MA. Metabolic Strategies of Melanoma Cells: Mechanisms, Interactions with the Tumor Microenvironment, and Therapeutic Implications. Pigment Cell Melanoma Res 31(1):11-30, 2018. e-Pub 2018. PMID: 29049843.
      18. Barlow-Mosha L, Musiime V, Davies MA, Prendergast AJ, Musoke P, Siberry G, Penazzato M. Universal antiretroviral therapy for HIV-infected children: a review of the benefits and risks to consider during implementation. J Int AIDS Soc 20(1):21552, 2017. e-Pub 2017. PMID: 28691434.
      19. Singh E, Naidu G, Davies MA, Bohlius J. HIV-associated malignancies in children. Curr Opin HIV AIDS 12(1):77-83, 2017. e-Pub 2017. PMID: 27685986.
      20. Cohen JV, Tawbi H, Margolin KA, Amravadi R, Bosenberg M, Brastianos PK, Chiang VL, de Groot J, Glitza IC, Herlyn M, Holmen SL, Jilaveanu LB, Lassman A, Moschos S, Postow MA, Thomas R, Tsiouris JA, Wen P, White RM, Turnham T, Davies MA, HM K. Melanoma Central Nervous System Metastases: Current Approaches, Challenges, and Opportunities. Pigment Cell Melanoma Res 29(6):627-642, 2016. e-Pub 2016.
      21. Cohen JV, Tawbi H, Margolin KA, Amravadi R, Bosenberg M, Brastianos PK, Chiang VL, de Groot J, Glitza IC, Herlyn M, Holmen SL, Jilaveanu LB, Lassman A, Moschos S, Postow MA, Thomas R, Tsiouris JA, Wen P, White RM, Turnham T, Davies MA, Kluger HM. Melanoma central nervous system metastases: current approaches, challenges, and opportunities. Pigment Cell Melanoma Res 29(6):627-642, 2016. e-Pub 2016. PMID: 27615400.
      22. Davies MA. Molecular Approaches to Tumor Inhibition in Melanoma. Clinical Advances in Hematology & Oncology 13(12), 2015. e-Pub 2015. PMID: 27058849.
      23. Ford N, Meintjes G, Pozniak A, Bygrave H, Hill A, Peter T, Davies MA, Grinsztejn B, Calmy A, Kumarasamy N, Phanuphak P, deBeaudrap P, Vitoria M, Doherty M, Stevens W, Siberry GK. The future role of CD4 cell count for monitoring antiretroviral therapy. Lancet Infect Dis 15(2):241-7, 2015. e-Pub 2015. PMID: 25467647.
      24. Glitza IC, Davies MA. Genotyping of Cutaneous Melanoma. Chin Clin Oncol 3(3):27, 2014. e-Pub 2014. PMID: 25632386.
      25. Chen G, Davies MA. Targeted Therapy Resistance Mechanisms and Therapeutic Implications in Melanoma. Hematology/Oncology Clinics of North America 28(3):523-536, 2014. e-Pub 2014. PMID: 24880945.
      26. Shtivelman E, Davies MA, Hwu P, Yang J, Lotem M, Oren M, Flaherty KT, Fisher DE. Pathways and therapeutic targets in melanoma. Oncotarget 5(7):1701-52, 2014. e-Pub 2014. PMID: 24743024.
      27. Davies MA. Targeted Therapy for Cutaneous Melanoma: Beyond BRAF. J Patient-Centered Res Rev 1(1):12-20, 2014. e-Pub 2014.
      28. Bucheit AD, Davies MA. Emerging insights into resistance to BRAF inhibitors in melanoma. Biochem Pharmacol 87(3):381-9, 2014. e-Pub 2014. PMID: 24291778.
      29. Kwong LN, Davies MA. Targeted therapy for melanoma: rational combinatorial approaches. Oncogene 33(1):1-9, 2014. e-Pub 2014. PMID: 23416974.
      30. Kwong LN, Davies MA. Navigating the therapeutic complexity of PI3K pathway inhibition in melanoma. Clin Cancer Res 19(19):5310-9, 2013. e-Pub 2013. PMID: 24089444.
      31. Schutte DL, Davies MA, Goris ED. The implications of genomics on the nursing care of adults with neuropsychiatric conditions. J Nurs Scholarsh 45(1):79-88, 2013. e-Pub 2013. PMID: 23368536.
      32. Woodman SE, Lazar AJ, Aldape KD, Davies MA. New strategies in melanoma: molecular testing in advanced disease. Clin Cancer Res 18(5):1195-200, 2012. e-Pub 2012. PMID: 22275506.
      33. Davies MA. The role of the PI3K-AKT pathway in melanoma. Cancer J 18(2):142-7, 2012. e-Pub 2012. PMID: 22453015.
      34. Chen G, Davies MA. Emerging insights into the molecular biology of brain metastases. Biochem Pharmacol 83(3):305-14, 2012. e-Pub 2012. PMID: 21946085.
      35. Davies MA. Targeted therapy for brain metastases. Adv Pharmacol 65:109-42, 2012. e-Pub 2012. PMID: 22959025.
      36. Davies MA, Gershenwald JE. Targeted therapy for melanoma: a primer. Surg Oncol Clin N Am 20(1):165-80, 2011. e-Pub 2011. PMID: 21111965.
      37. Davies MA, Samuels Y. Analysis of the genome to personalize therapy for melanoma. Oncogene 29(41):5545-55, 2010. e-Pub 2010. PMID: 20697348.
      38. Woodman SE, Davies MA. Targeting KIT in melanoma: a paradigm of molecular medicine and targeted therapeutics. Biochem Pharmacol 80(5):568-74, 2010. e-Pub 2010. PMID: 20457136.
      39. Davies MA, Sheffler DJ, Roth BL. Aripiprazole: a novel atypical antipsychotic drug with a uniquely robust pharmacology. CNS Drug Rev 10(4):317-36, 2004. e-Pub 2004. PMID: 15592581.
      40. Mobbs RJ, Vonau M, Davies MA. Death after late failure of endoscopic third ventriculostomy: a potential solution. Neurosurgery 53(2):384-5; discussion 385-6, 2003. e-Pub 2003. PMID: 12925256.
      41. Davies MA, Teo C. Management of traumatic cerebrospinal fluid fistula. J Craniomaxillofac Trauma 1(2):9-17, 1995. e-Pub 1995. PMID: 11951463.

      Professional Educational Materials

      1. Davies, MA, Lipson E. Metastatic Melanoma: Incorporating LAG3 Inhibitors Into the Treatment Paradigm. Medscape Oncology, 2023.
      2. Davies MA, Ariyan C. SMR/Medscape Video Series titled, “A New Era of Progress for Melanoma: Leveling-Up with Immunotherapy”. Immune Checkpoint and BRAF/MEK Inhibitor-directed Therapies for Advanced Melanoma, 2022.

      Other Articles

      1. Herb J, Bassett RL, Torres-Cabala CA, Prieto VG, Patel SP, Holder AM, Fisher SB, Lucci A, Wargo J, Amaria RN, Davies MA, Glitza Oliva IC, Tawbi HA, McQuade J, Ikeguchi AP, Wong MK, Diab AK, Gershenwald JE, Ross MI, Weiser R Correction: Real-World Outcomes for Patients with Clinically Node-Positive Melanoma Undergoing Neoadjuvant Immunotherapy and Nodal Dissection. Ann Surg Oncol 33(7):6758-6759, 2026. PMID: 42032252.
      2. Nagarajan, P, Piao, J, Ning, J, Noordenbos, LE, Curry, JL, Torres Cabala, CA, Diwan, AH, Ivan, D, Aung, PP, Ross, MI, Royal, RE, Wargo, J, Wang, W, Samdani, RT, Lazar, A, Rashid, A, Davies, MA, Prieto, V, Gershenwald, JE, Tetzlaff, M Corrigendum to “Prognostic Model for Patient Survival in Primary Anorectal Mucosal Melanoma. Modern Pathology 38(8), 2025. PMID: 40541156.
      3. Koul, D, Parthasarathy, R, Shen, R, Davies, MA, Jasser, SA, Chintala, SK, Rao, JS, Sun, Y, Benvenisite, EN, Liu, TJ, Yung, WA Retraction Note. Oncogene 44(17):1211, 2025. PMID: 40200095.
      4. Hussey H, Vreede H, Davies MA, Heekes A, Kalk E, Hardie D, van Zyl G, Naidoo M, Morden E, Bam JL, Zinyakatira N, Centner CM, Maritz J, Opie J, Chapanduka Z, Mahomed H, Smith M, Cois A, Pienaar D, Redd AD, Preiser W, Wilkinson R, Boulle A, Hsiao NY Correction: SARS-CoV-2 seroepidemiology in Cape Town, South Africa, and implications for future outbreaks in low-income communities. PLOS Glob Public Health 5(6):e0004804, 2025. PMID: 40504816.
      5. Kim, ST, Chu, Y, Misoi, MW, Suarez-Almazor, M, Tayar, JH, Lu, H, Buni, M, Kramer, J, Rodriguez, E, Hussain, Z, Neelapu, SS, Wang, RJ, Shah, AY, Tannir, NM, Campbell, M, Gibbons, DL, Cascone, T, Lu, C, Blumenschein, GR, Altan, M, Lim, B, Valero, V, Loghin, ME, Tu, J, Westin, SN, Naing, A, Garcia-Manero, G, Hassan, NA, Tawbi, H, Hwu, P, Oliva, IC, Davies, MA, Patel, SP, Zou, J, Futreal, A, Diab, A, Wang, L, Nurieva, R Author Correction. Nature communications 15(1), 2024. PMID: 38965214.
      6. Glitza, IC, Ferguson, SD, Bassett Jr, R, Foster, AP, John, I, Hennegan, TD, Rohlfs, ML, Richard, J, Iqbal, M, Dett, TK, Lacey, C, Jackson, N, Rodgers, TE, Phillips, S, Duncan, S, Haydu, LE, Lin, R, Amaria, RN, Wong, MK, Diab, A, Yee, C, Patel, SP, McQuade, JL, Fischer, G, McCutcheon, IE, O'Brien, BJ, Tummala, S, Debnam, M, Guha-Thakurta, N, Wargo, J, Carapeto, F, Hudgens, CW, Huse, J, Tetzlaff, M, Burton, EM, Tawbi, H, Davies, MA Author Correction. Nature medicine 30(6):1787, 2024. PMID: 38649781.
      7. Ford N, Patten G, Rangaraj A, Davies MA, Meintjes G, Ellman T Outcomes of people living with HIV after hospital discharge: a systematic review and meta-analysis. Lancet HIV 9(3):e150-e159, 2022. PMID: 35245507.
      8. Woo, XY, Giordano, J, Srivastava, A, Zhao, ZM, Lloyd, M, de Bruijn, R, Suh, YS, Patidar, R, Chen, L, Scherer, S, Bailey, M, Yang, CH, Cortes-Sanchez, E, Xi, Y, Wang, J, Wickramasinghe, JM, Kossenkov, AV, Rebecca, VW, Sun, H, Mashl, RJ, Davies, S, Jeon, R, Frech, C, Randjelovic, J, Rosains, J, Galimi, F, Bertotti, A, Lafferty, A, O’Farrell, AC, Modave, E, Fang, B, Roth, JA, Meric-Bernstam, F, Davies, MA, Zheng, X, Zhang, X, Akcakanat, A, Yap, TA, Ha, MJ, Chen, H, Kopetz, S, Menter, DG, Westin, SN, Kim, M, Dai, B, Gibbons, DL, Tapia, C, Jensen, VB, Yennu Nanda, VG, Mælandsmo, GM Author Correction. Nature Genetics 53(5):761, 2021. PMID: 33608693.
      9. Long GV, Flaherty KT, Stroyakovskiy D, Gogas H, Levchenko E, de Braud F, Larkin J, Garbe C, Jouary T, Hauschild A, Chiarion-Sileni V, Lebbe C, Mandala M, Millward M, Arance A, Bondarenko I, Haanen JBAG, Hansson J, Utikal J, Ferraresi V, Mohr P, Probachai V, Schadendorf D, Nathan P, Robert C, Ribas A, Davies MA, Lane SR, Legos JJ, Mookerjee B, Grob JJ Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study. Ann Oncol 30(11):1848, 2019. PMID: 31406976.
      10. Johnson DH, Zobniw CM, Trinh VA, Ma J, Bassett RL Jr, Abdel-Wahab N, Anderson J, Davis JE, Joseph J, Uemura M, Noman A, Abu-Sbeih H, Yee C, Amaria R, Patel S, Tawbi H, Glitza IC, Davies MA, Wong MK, Woodman S, Hwu WJ, Hwu P, Wang Y, Diab A Correction to: Infliximab associated with faster symptom resolution compared with corticosteroids alone for the management of immune-related enterocolitis. J Immunother Cancer 7(1):107, 2019. PMID: 30995944.
      11. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med 24(12):1941, 2018. PMID: 30361510.
      12. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med 24(12):1942, 2018. PMID: 30361511.
      13. Ford N, Shubber Z, Meintjes G, Grinsztejn B, Eholie S, Mills EJ, Davies MA, Vitoria M, Penazzato M, Nsanzimana S, Frigati L, O'Brien D, Ellman T, Ajose O, Calmy A, Doherty M Causes of hospital admission among people living with HIV worldwide: a systematic review and meta-analysis. Lancet HIV 2(10):e438-44, 2015. PMID: 26423651.
      14. Mbeye NM, ter Kuile FO, Davies MA, Phiri KS, Egger M, Wandeler G Cotrimoxazole prophylactic treatment prevents malaria in children in sub-Saharan Africa: systematic review and meta-analysis. Trop Med Int Health 19(9):1057-67, 2014. PMID: 25039469.
      15. Mugglin C, Wandeler G, Estill J, Egger M, Bender N, Davies MA, Keiser O Retention in care of HIV-infected children from HIV test to start of antiretroviral therapy: systematic review. PLoS One 8(2):e56446, 2013. PMID: 23437135.
      16. Wettstein C, Mugglin C, Egger M, Blaser N, Vizcaya LS, Estill J, Bender N, Davies MA, Wandeler G, Keiser O Missed opportunities to prevent mother-to-child-transmission: systematic review and meta-analysis. AIDS 26(18):2361-73, 2012. PMID: 22948267.
      17. Koul D, Parthasarathy R, Shen R, Davies MA, Jasser SA, Chintala SK, Rao JS, Sun Y, Benvenisite EN, Liu TJ, Yung WK Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN. Oncogene 20(46):6669-78, 2001. PMID: 11709701.

      Editorials

      1. Mendelsohn AS, De Sa A, Morden E, Botha B, Boulle A, Paleker M, Davies MA. COVID-19 wave 4 in Western Cape Province, South Africa: Fewer hospitalisations, but new challenges for a depleted workforce. S Afr Med J 112(2):13496, 2022. PMID: 35139985.
      2. Davies MA. Is It Safe to Stop Anti-PD-1 Immunotherapy in Patients With Metastatic Melanoma Who Achieve a Complete Response?. J Clin Oncol 38(15):1645-1647, 2020. PMID: 32097093.
      3. Ford N, Penazzato M, Vitoria M, Doherty M, Davies MA, Zaniewski E, Tymejczyk O, Egger M, Nash D. The contribution of observational studies in supporting the WHO 'treat all' recommendation for HIV/AIDS. J Virus Erad 4(Suppl 2):5-8, 2018. PMID: 30515308.
      4. Enane LA, Davies MA, Leroy V, Edmonds A, Apondi E, Adedimeji A, Vreeman RC. Traversing the cascade: urgent research priorities for implementing the 'treat all' strategy for children and adolescents living with HIV in sub-Saharan Africa. J Virus Erad 4(Suppl 2):40-46, 2018. PMID: 30515313.
      5. de Waal R, Lessells R, Hauser A, Kouyos R, Davies MA, Egger M, Wandeler G. HIV drug resistance in sub-Saharan Africa: public health questions and the potential role of real-world data and mathematical modelling. J Virus Erad 4(Suppl 2):55-58, 2018. PMID: 30515315.
      6. McQuade JL, Daniel CR, Hess KR, Davies MA. Sex as a predictor of response to cancer immunotherapy. Lancet Oncology 19(8):376, 2018. PMID: 30102226.
      7. Davies MA, Hamlyn E. HIV and adolescents: challenges and opportunities. Curr Opin HIV AIDS 13(3):167-169, 2018. PMID: 29517500.
      8. Davies MA. BRAF in early stage melanoma: rationale for testing and treatment?. Br J Dermatol 173(1):9-10, 2015. PMID: 26174638.
      9. Davies MA, Pinto J. Targeting 90-90-90--don't leave children and adolescents behind. J Int AIDS Soc 18(Suppl 6):20745, 2015. PMID: 26639121.
      10. Davies MA. Finding the Right Balance of BRAF Inhibition in Melanoma. Cancer Discov 4(5):510-2, 2014. PMID: 24795008.
      11. Davies MA, Kopetz S. Overcoming resistance to MAPK pathway inhibitors. J Natl Cancer Inst 105(1):9-10, 2013. PMID: 23250957.
      12. Davies MA. Special issue on melanoma. Cancer J 18(2):115-6, 2012. PMID: 22453010.

      Abstracts

      1. Burton E, Honaker V, Milton D, Glitza IC, Amaria R, Patel S, Diab A, Wong M, Mcquade J, Chung C, Wefel JS, Li J, Davies MA, Tawbi HA. Atezolizumab, bevacizumab, and cobimetinib (TACo) in patients (pts) with PD1 refractory melanoma brain metastases (MBM). 2023 ESMO Congress 34(S2):S652-S653, 2023. e-Pub 2023.
      2. Glitza IC, Phillips S, John I, Bassett RL, Lin R, Rohlfs ML, Richard J, Iqbal M, Hennegan T, McCutcheon IE, Ferguson S, O'Brien B, Tummala S, Guha-Thakurta N, Debnam M, Tawbi HA, Burton E, Davies MA. Concurrent intrathecal (IT) and intravenous (IV) nivolumab (N) for melanoma (MM) patients (pts) with leptomeningeal disease (LMD). 2023 ESMO Congress 34(SUPPLEMENT 2):S652, 2023. e-Pub 2023.
      3. Eroglu Z, Mehnert JM, Giobbie-Hurder A, Kendra KL, Kim In G, Salama AKS, Doolittle GC, Sosman JA, Valerin JB, Medina TM, Lutzky J, Moschos SJ, Khushalani NI, Markowitz J, Takebe N, Chen HX, Knight LW, Davies MA, Sullivan RJ. Randomized phase II trial of dabrafenib and trametinib with or without navitoclax in patients (pts) with BRAF-mutant (MT) metastatic melanoma (MM) (CTEP P9466). 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
      4. Glitza IC, John I, Phillips S, See L, Bassett RL, Lin R, Rohlfs ML, Richard J, Iqbal M, Hennegan T, McCutcheon IE, Ferguson SD, Morad G, O'Brien JO, Tummala S, Guha-Thakurta N, Debnam M, Tawbi HA, Burton EM, Davies MA. Safety and preliminary efficacy of intrathecal (IT) and intravenous (IV) nivolumab (N) for patients (pts) with leptomeningeal disease (LMD). 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
      5. Hennegan T, Burton EM, Simpson L, Prieto VG, Ross MI, Glitza IC, Beal LG, Gershenwald JE, Tawbi HA, Wong M KK, Wang Z, Bassett RL, Lucci A, Lee JE, Fisher SB, Patel SP, McQuade JL, Davies MA, Wargo JA, Amaria RN. Expanded cohort and extended follow-up of neoadjuvant plus adjuvant (neo + adj) dabrafenib (D) and trametinib (T) in patients (pts) with surgically resectable stage (stg) III/IV melanoma. 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
      6. Cass S, Tobin J, Seo YD, Gener-Ricos G, Keung E ZY, Burton EM, Walsh DM, Davies MA, McQuade JL, Lazar AJ, Hampel PJ, Wargo JA, Ferrajoli A. Efficacy of immune checkpoint inhibitors for the treatment of advanced melanoma (AM) in patients with concomitant chronic lymphocytic leukemia (CLL). 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
      7. Phillips S, Burton EM, Kreidieh FY, Glitza IC, McQuade JL, Amaria RN, Diab A, Patel SP, Wong M KK, Li J, Chung C, Milton DR, Malke J, Simon J, Wefei JS, Davies MA, Tawbi HA. Phase II study of nivolumab (nivo) in combination with relatlimab (rela) in patients (pts) with active melanoma brain metastases (MBM). 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
      8. Morad G, Yang Y, Duncan S, Ferguson SD, Wargo JA, Burton EM, Tawbi HA, Davies MA, Liang H, Glitza IC. Longitudinal single-cell (sc) immune profiling of cerebrospinal fluid (CSF) from melanoma patients (pts) with leptomeningeal disease (LMD) treated with intrathecal (IT) and intravenous (IV) nivolumab (N). 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
      9. Patel SP, Forget MA, Kreidieh FY, Pelster M, Davies MA, Amaria RN, Gombos DS, Bernatchez C. Tumor infiltrating lymphocyte (TIL) harvest and ex vivo expansion from primary and metastatic (met) uveal melanoma (UM) tumors. 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
      10. Hasanov M, Milton DR, Lo SN, Gershenwald JE, Simon J, Long GV, Scolyer RA, Davies MA. External validation and nomogram for risk factors of CNS metastasis in patients with clinically localized melanoma. 2023 ASCO Annual Meeting, 2023. e-Pub 2023.
      11. Kumar S, Pelster MS, Hasanov M, Milton DR, Guerrieri RA, Hudgens C, Ledesma D, Wang F, Fischer G, Haydu LE, Yennu Nanda V, McQuade J, Kwong L, Huse J, Lazar AJ, Tetzlaff MT, Gershenwald JE, Joon AY, Chen K, Ram PT, Ferguson SD, Davies MA. Multivariate (MV) analysis of clinical, molecular and immune features associated with overall survival (OS) in patients (pts) with melanoma brain metastases (MBMs). The 19th International Congress of the Society for Melanoma Research, 2022. e-Pub 2022.
      12. Hasanov M, Milton D, Davies AB, Sirmans E, Saberian C, Posada EL, Osusunju S, Gershenwald JE, Torres-Cabala CA, Burton EM, Colen R, Huse J, Glitza Oliva IC, Chung C, McAleer MF, McGovern SL, Yeboa DN, Kim BY, Prabhu SS, McCutcheon IE, Weinberg JS, Lang FF, Tawbi HT, Li J, Haydu LE, Ferguson SD, Davies MA. Changes in Overall Survival and Prognostic Factors in Melanoma Brain Metastasis (MBM) Patients. The 19th International Congress of the Society for Melanoma Research, 2022. e-Pub 2022.
      13. Wilmott JS, Tawbi HT, Engh JA, Amankulor N, Shivalingam B, Banerjee H, Vergara IA, Lee H, Johansson PA, Ferguson PM, Saiag P, Robert C, Grob JJ, Butterfield LH, Scolyer RA, Kirkwood JM, Long GV, Davies MA. Clinical features associated with outcomes and biomarker analysis of dabrafenib plus trametinib (DT) in patients (pts) with BRAF-mutant melanoma brain metastases (MBMs). The 19th International Congress of the Society for Melanoma Research, 2022. e-Pub 2022.
      14. de Groot E, Guerrieri RA, Knighton B, Wubbenhorst B, D'Andrea K, Xiao M, Baxter K, Kossenkov A, Herlyn M, Nathanson K, Davies MA, Roszik J, Yennu Nanda VG. Anti-melanoma activity of the PARP inhibitor (PARPi) Talazoparib combined with anti-PD1 in patient-derived xenografts (PDX) in a humanized mouse model. The 19th International Congress of the Society for Melanoma Research, 2022. e-Pub 2022.
      15. Guerrieri RA, Fischer G, Kircher D, Ledesma D, Joon AY, Cortez JR, Knighton BG, Hudgens C, Hu Q, Yennu Nanda VG, Deng W, Haydu LE, Gershenwald JE, Lazar AJ, Tetzlaff MT, Holmen S, Davies MA. The Role of Oxidative Phosphorylation (OXPHOS) in Metastatic Melanoma (MM) Formation and Growth. The 19th International Congress of the Society for Melanoma Research, 2022. e-Pub 2022.
      16. White MG, Vellano CP, Andrews MC, Witt RG, Chelvanambi M, McQuade JL, Burton EM, Chu Y, Lastrapes MJ, Lau M, Banerjee H, Lazar AJ, Davies MA, Woodman SE, Wang L, Moran AE, Long GV, Heffernan TP, Marszalek JR, Wargo JA. Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy. 2022 ASCO Annual Meeting, 2022. e-Pub 2022.
      17. Abdel-Wahab N, Kus T, Bentebibel S, McQuade J, Glitza IC, Amaria R, Patel S, Wong MK, Tawbi H, Davies MA, Peterson S, Shete S, Yee C, Kavelaars A, Suarez-Almazor M, Diab A. Immune-Related Adverse Events and Symptom Burden in Melanoma Patients Receiving Adjuvant Immune Checkpoint Inhibitor. 2022 ASCO Annual Meeting, 2022. e-Pub 2022.
      18. Wilmott JS, Banerjee H, Saiag P, Robert C, Grob J, Long GV, Davies MA. Baseline treatment with corticosteroids is associated with worse outcomes with dabrafenib and trametinib (DT) treatment in patients (pts) with BRAF-mutant melanoma brain metastases (MBMs) in COMBI-MB. 2022 ASCO Annual Meeting, 2022. e-Pub 2022.
      19. Abdel-Wahab N, Montazari EJ, Spillson CA, Bentebibel S, Awiwi MO, Elsayes KM, Gao J, Altan M, Wong M, Glitza IC, Amaria R, McQuade J, Patel S, Tawbi H, Davies MA, Yee C, Sharma P, Allison J, Ekmekcioglu S, Diab A. Tocilizumab in Combination with Ipilimumab and Nivolumab in Solid Tumors. 2022 ASCO Annual Meeting, 2022. e-Pub 2022.
      20. Wilmott JS, Banerjee H, Saiag P, Robert C, Grob J, Long GV, Davies MA. Association of baseline corticosteroid treatment with outcomes for patients (pts) with BRAF-mutant melanoma brain metastases (MBMs) in COMBI-MB treated with dabrafenib and trametinib (DT). 2022 ASCO Annual Meeting, 2022. e-Pub 2022.
      21. Schadendorf D, Hauschild A, Mandalà M, Kirkwood JM, Robert C, Grob J, Nathan PD, Davies MA, Banerjee H, Shah R, Lau MR, Dummer R, Long GV. Adjuvant dabrafenib + trametinib (D + T) vs placebo in patients with resected stage III BRAFV600-mutant melanoma: updated 5-year distant metastases-free survival (DMFS) analysis of COMBI-AD. 2022 ASCO Annual Meeting, 2022. e-Pub 2022.
      22. Fischer GM, Guerrieri RA, Hu Q, Carapeto FC, Joon AY, Gopal VY, Knighton B, Deng W, Haydu LE, Gershenwald JE, Lazar AJ, Tetzlaff MT, Davies MA. The role of oxidative phosphorylation (OXPHOS) in melanoma brain metastasis (MBM) formation and growth. AACR Virtual Annual Meeting 2021, 2021. e-Pub 2021.
      23. Hahn A, Xu M, Li J, Haydu LE, Wadud Khan MA, Gide TN, Menzies AM, Hudgens CW, Nowicki TS, Gershenwald JE, Ribas A, Tetzlaff MT, Lazar AJ, Willmont J, Wargo J, Futreal A, Zhang J, Davies MA, McQuade JL. Obesity is associated with lower tumor oxidative phosphorylation (OXPHOS) in metastatic melanoma (MM). AACR Virtual Annual Meeting 2021, 2021. e-Pub 2021.
      24. Pattipaka T, Davies MA, Sullivan R, Lang C, Lau M. Real-World Characterization of Pyrexia in Melanoma Patients Treated with Dabrafebib and Trametinib. 10th World Congress of Melanoma/17th EADO Congress 2021, 2021. e-Pub 2021.
      25. Colen RR, Ologun GO, Zinn P, AK M, Arora R, Burton EM, Glitza IC, Tawbi H, Patel SP, Diab A, Wong MK, McQuade JL, Ross MI, Ahmed S, Elshafeey N, Gershenwald JE, Davies MA, Tetzlaff MT, Amaria RN, Wargo JA. Radiomic signatures to predict response to targeted therapy and immune checkpoint blockade in melanoma patients (pts) on neoadjuvant therapy. 2020 ASCO Virtual Scientific Program, 2020. e-Pub 2020.
      26. Glitza IC, Phillips S, Brown C, Haymaker CL, Bassett RL, Lee JJ, Rohlfs ML, Richard J, Iqbal M, John I, McCutcheon IE, Ferguson SD, Heimberger AB, O'Brien BJ, Tummala S, Guha-Thakurta N, Debnam M, Burton EM, Tawbi H, Davies MA. Single-center phase I/Ib study of concurrent intrathecal (IT) and intravenous (IV) nivolumab (N) for metastatic melanoma (MM) patients (pts) with leptomeningeal disease (LMD). 2020 ASCO Virtual Scientific Program, 2020. e-Pub 2020.
      27. Guerra V, Ologun GO, Haydu LE, Keung E, Burton EM, Tawbi H, Wierda WG, Davies MA, Wargo JA, Ferrajoli A. Efficacy of immune checkpoint inhibitors for the treatment of metastatic melanoma (MM) in patients with concurrent chronic lymphocytic leukemia (CLL). 2020 ASCO Virtual Scientific Program, 2020. e-Pub 2020.
      28. Tawbi H, Peng W, Phillips S, Milton DR, Amaria RN, Diab A, Glitza IC, Patel SP, Wong MK, Yee C, McQuade JL, Tetzlaff MT, Lazar AJ, Shepherd M, Cain S, Burton EM, Hwu P, Davies MA. Safety results from phase I/II study of the PI3Kβ inhibitor GSK2636771 (G) in combination with pembrolizumab (P) in patients (pts) with PD-1 refractory metastatic melanoma (MM) and PTEN loss. 2020 ASCO Virtual Scientific Program, 2020. e-Pub 2020.
      29. Ogata D, Haydu L, Glitza IC, Patel SP, Tawbi H, McQuade J, Diab A, Ekmekcioglu S, Wong M, Amaria R, Davies MA. The efficacy of anti-PD-1 in metastatic acral and mucosal melanoma patients (pts). 2019 SMR Congress, 2019. e-Pub 2019.
      30. Rosenbaum S, Knecht M, Mollaee M, Zhong Z, Erkes DA, McCue P, Berger AC, Lo JA, Fisher DE, Gershenwald JE, Davies MA, Purwin TJ, Aplin A. FOXD3 regulates VISTA expression in melanoma. 2019 SMR Congress, 2019. e-Pub 2019.
      31. Robert C, Grob JJ, Stroyakovskiy D, Karaszewska B, Hauschild A, Levchenko E, Sileni VC, Schachter J, Garbe C, Bondarenko I, Nathan P, Ribas A, Davies MA, Flaherty K, Burgess P, Tan M, Gasal E, Schadendorf D, Long GV. Characteristics of patients (pts) with a complete response (CR) treated with dabrafenib plus trametinib (D+T) combination therapy: findings from COMBI-d and COMBI-v 5-year analysis. 2019 SMR Congress, 2019. e-Pub 2019.
      32. Rebecca VW, Xiao M, Fingerman D, Martorella A, Alicea G, Kossenkov A, Liu Q, Gopal V, Davies MA, Herlyn M. Drug repurposing screen using BTAFi/MEKi- and immunotherapy-resistant PDX identifies salvage strategies. 2019 SMR Congress, 2019. e-Pub 2019.
      33. Capparelli C, Tiago M, Purwin T, Rosenbaum S, Cai W, Richard Z, Kumar G, Snook A, Rortina P, Cukierman E, Davies MA, Aplin A. Loss of SOX10 induces a transition to an invasive/dormant-like phenotype in Melanoma. 2019 SMR Congress, 2019. e-Pub 2019.
      34. Pelster M, Haydu L, Gruschkus S, Gombos DS, Davies MA, Hwu P, Wong M, Amaria R, Diab A, Glitza IC, Tawbi H, McQuade J, Patel SP. CNS metastases in uveal melanoma. 2019 SMR Congress, 2019. e-Pub 2019.
      35. Kircher DA, Parkman GL, Fischer GM, Stehn C, Grossmann AH, Boucher K, McMahon M, Davies MA, Mendoza MC, VanBrocklin MW, Holmen S. AKT1 E17K activates focal adhesion kinase and promotes melanoma brain metastasis. 2019 SMR Congress, 2019. e-Pub 2019.
      36. Holbrook K, Lutzky J, Davies MA, Davis J, Glitza IC, Amaria R, Diab A, Patel SP, Amin A, Tawbi H. Intracranial Anti-Tumor Activity with Encorafenib Plus Binimetinib in Patients with Melanoma Brain Metastases: A Case Series. 2019 SMR Congress, 2019. e-Pub 2019.
      37. Fischer GM, Carapeto F, Tetzlaff M, Hudgens C, Huse J, Davies MA, Ferguson S. Preclinical modeling of leptomeningeal disease (LMD) from melanoma to facilitate therapeutic development. 2019 SMR Congress, 2019. e-Pub 2019.
      38. Davies MA, Weber JS, Flaherty K, McArthur G, Hamid O, Reddy M, Golden A, Culbertson J, Thomas C, Tawbi H, Long GV. A Phase 2, open-label, randomized, multicenter trial of Encorafenib + Binimetinib evaluating a standard-dose and a high-dose regimen in patients with BRAFV600-mutant melanoma brain metastasis (MBM) (POLARIS). 2019 SMR Congress, 2019. e-Pub 2019.
      39. Syeda MM, Wiggins J, Davies MA, Robert C, Long GV, Grob JJ, Flaherty K, Gasal E, Squires M, Garrett J, Brase J, Polsky D. Circulating tumor DNA (ctDNA) kinetics and survival outcomes in patients (pts) with metastatic melanoma (MM) and brain metastases (BM) treated with dabrafenib (D)+ trametinib (T) in the COMBI-MB trial. 2019 SMR Congress, 2019. e-Pub 2019.
      40. Saberian C, Ludford K, Roszik J, Gruschkus S, Johnson DH, Bernatchez C, Davies MA, Haymaker C, Diab A. Analysis of tumor mutation burden (TMB), PD-L1 status and clinical outcomes with checkpoint inhibitors (CPI) in acral melanoma (AM). 2019 SMR Congress, 2019. e-Pub 2019.
      41. Menzies AM, Rozeman EA, Amaria RN, Huang AC, Scolyer RA, Tetzlaff MT, Van de Wiel BA, Lo S, Tarhini A, Tawbi H, Burton EM, Karakousis G, Ascierto PA, Spillane A, Davies MA, Van Akkooi AC, Mitchell TC, Long GV, Wargo JA, Blank CU. Pathological response and survival with neoadjuvant therapy in melanoma: A pooled analysis from the International Neoadjuvant Melanoma Consortium (INMC). 2019 ASCO Annual Meeting, 2019. e-Pub 2019.
      42. Amaria RN, Haymaker CL, Forget M, Bassett R, Cormier JN, Davies MA, Diab A, Gershenwald JE, Glitza IC, Lee JE, Lucci A, McQuade JL, Patel SP, Royal RE, Ross M, Tawbi H, Wargo J, Wong MK, Bernatchez C, Hwu P. Lymphodepletion (LD), tumor-infiltrating lymphocytes (TIL) and high (HD-IL2) versus low-dose (LD-IL2) IL-2 followed by pembrolizumab (pembro) in patients (pts) with metastatic melanoma (MM). 2019 ASCO Annual Meeting, 2019. e-Pub 2019.
      43. Jones AL, Joon A, Haydu LE, Lazar AJ, Tetzlaff MT, Ravi V, Davies MA. Outcomes of melanoma soft parts/clear cell sarcoma (MSP/CCS) patients (pts) with immune and targeted therapies. 2019 ASCO Annual Meeting, 2019. e-Pub 2019.
      44. Syeda MM, Wiggins J, Corless B, Long GV, Flaherty K, Schadendorf D, Nathan PD, Robert C, Ribas A, Davies MA, Grob JJ, Gasal E, Squires M, Marker M, Brase JC, Polsky D. Circulating tumor DNA (ctDNA) kinetics to predict survival in patients (pts) with unresectable or metastatic melanoma treated with dabrafenib (D) or D + trametinib (T). 2019 ASCO Annual Meeting, 2019. e-Pub 2019.
      45. Nathan PD, Robert C, Grob JJ, Stroyakovskiy D, Karaszewska B, Hauschild A, Levchenko E, Sileni VC, Schachter J, Garbe C, Bondarenko I, Davies MA, Ribas A, Flaherty K, Burgess P, Tan M, Gasal E, Schadendorf D, Long GV. Five-year analysis on the long-term effects of dabrafenib plus trametinib (D + T) in patients with BRAF V600–mutant unresectable or metastatic melanoma. 2019 ASCO Annual Meeting, 2019. e-Pub 2019.
      46. Burton EM, Woody T, Glitza IC, Amaria RN, Keung E, Diab A, Patel SP, Wong MK, Yee C, Hwu P, McQuade JL, Woodman SE, Tetzlaff MT, Davies MA, Wargo JA, Rai K, Tawbi H. A phase II study of oral azacitidine (CC-486) in combination with pembrolizumab (PEMBRO) in patients (pts) with metastatic melanoma (MM). 2019 ASCO Annual Meeting, 2019. e-Pub 2019.
      47. Yennu Nanda VG, Gammon S, Prasad R, Knighton B, Pisaneschi F, Feng N, Williams L, Pramanik S, Sudderth J, Sui D, Fischer GM, Deng W, Peng W, Wang J, McQuade JL, Tetzlaff M, Di Francesco ME, Marszalek J, Piwnica-Worms D, DeBerardinis RJ, Davies MA. A novel mitochondrial inhibitor overcomes resistance to BRAF and MEK inhibition in melanoma. 2019 Melanoma Research Alliance 11th Annual Scientific Retreat, 2019. e-Pub 2019.
      48. Carapeto FCL, Fischer GM, Joon AY, Chen H, Haydu L, Lee S, Saul M, Appana S, Thompson JF, Mann GJ, McQuade JL, Lazar AJ, Kirkwood J, Scolyer RA, Long GV, Davies MA. Analysis of molecular and immune features that correlate with serum lactate dehydrogenase (LDH) levels in patients (pts) with metastatic melanoma. AACR Special Conference on Melanoma: From Biology to Target, 2019. e-Pub 2019.
      49. Fischer GM, Kotrotsou A, Ahmed S, O'Neal P, Sahnoune I, Yennu-Nanda VG, Hudgens C, Knighton B, Colen R, Tetzlaff MT, Davies MA. Molecular, immunological, metabolic, and radiomic associations of oxidative phosphorylation (OXPHOS) in melanoma brain metastases (MBMs). AACR Special Conference on Melanoma: From Biology to Target, 2019. e-Pub 2019.
      50. Nagarajan P, Piao J, Ning J, Noordenbos LE, Curry JL, Torres-Cabala CA, Diwan AH, Aung PA, Ivan D, Ross MI, Royal RE, Wargo JA, Wang WL, Samdani R, Lazar AJ, Rashid A, Davies MA, Prieto VG, Gershenwald JE. Prognostic Model for Disease Specific Survival in Anorectal Melanoma. AACR Special Conference on Melanoma: From Biology to Target, 2019. e-Pub 2019.
      51. Davies MA. Will Targeted Therapy Replace Radiation for Melanoma Brain Metastases?. 2019 ASCO Annual Meeting, 2019. e-Pub 2019.
      52. Tiago M, Capparelli C, Erkes D, Purwin TD, Davies MA, Aplin AE. BET proteins inhibition to optimize BRAFi/MEKi therapy for mutant BRAF melanoma. 2018 SMR Congress International Meeting, 2018. e-Pub 2018.
      53. Glitza IC, Rohlfs ML, Iqbal M, Ricahrd J, Burton E, Duncan S, Brown C, Anderson J, Hwu P, Hwu WJ, Yee C, Patel S, Woodman S, Amaria R, Diab A, Tawbi H, Davies MA. A phase I/Ib study of concurrent intravenous (IV) and intrathecal (IT) nivolumab (Nivo) For melanoma patients (pts) with leptomeningeal disease (LMD). ESMO 2018 Congress International, 2018. e-Pub 2018.
      54. Andrews MC, Chen S, Prieto P, Marszalek J, Hudgens C, Tetzlaff MT, Amaria R, Gershenwald J, Davies MA, Arur S, Heffernan TP, Wargo J. Sexual dimorphism in response to BRAF mut melanoma target therapy. 2018 SMR International Congress Meeting, 2018. e-Pub 2018.
      55. Fischer GM, Yennu-Nanda VG, Tetzlaff MT, Lazar AJ, Carapeto F, de Macedo MP, Hudgens C, Holmen SL, Kircher DA, Knighton B, Davies MA. Oxidative Phosphorylation (OXPHOS): A Feature, Driver, and Therapeutic Target in Melanoma Brain Metastases (MBMs). 2018 SMR International Congress Meeting, 2018. e-Pub 2018.
      56. McQuade JL, Gopalakrishnan V, Spencer C, Andrews MC, Helmink B, Cogdill AP, Sirmans E, Haydu LE, Posada E, Burton E, Glitza I, Amaria R, Patel S, Diab A, Wong M, Tawbi HA, Hwu WJ, Davies MA, Hwu P, Jenq R, Nelson K, Daniel CR, Cohen L, Wargo J. The gut microbiome of melanoma patients is distinct from that of healthy individuals and is impacted by probiotic and antibiotic use. 2018 SMR International Congress Meeting, 2018. e-Pub 2018.
      57. Reddy S Helmink B, Zhang S, Blando J, Han G, Amaria R, Tawbi HA, Davies MA, Hwu P, Lee J, Gershenwald J, Burton E, Hudgens C, Keung E, Gaudreau P, Gopalakrishnan V, Reuben A, Andrews MC, Spencer C, Allison J, Sharma P, Tetzlaff MT, Wang L, Wargo J. B cell signature predicts survival in melanoma and response to immune checkpoint blockade (ICB). 2018 SMR International Congress Meeting, 2018. e-Pub 2018.
      58. Johnson DH, Bentebibel SE, Lecagoonporn S, Bernatchez C, Haymaker CL, Murthy R, Tam A, Yee C, Amaria RN, Patel SP, Tawbi H, Glitza IC, Davies MA, Hwu WJ, Hwu P, Overwijk WW, Diab A. Phase I/II dose escalation and expansion cohort safety and efficacy study of image guided intratumoral CD40 agonistic monoclonal antibody APX005M in combination with systemic pembrolizumab for treatment naive metastatic melanoma. 2018 ASCO Annual Meeting, 2018. e-Pub 2018.
      59. McQuade JL, Betof Warner A, Li M, Chon J, Haydu LE, Carrie D, Hess KR, Johnson DB, Menzies AM, Davies MA, Shoushtari AN. Association of body mass index (BMI) with overall survival (OS) in metastatic melanoma (MM) patients (pts) treated with combined anti-CTLA4 + anti-PD1. ASCO Annual Meeting 2018, 2018. e-Pub 2018.
      60. Schvartsman G, Ma J, Bassett RL, Haydu LE, Amaria RN, Hwu P, Hwu WJ, Diab A, Patel SP, Wong MK, Woodman S, Davies MA, Glitza IC, Tawbi H. Outcomes of metastatic melanoma (MM) patients (pts) after discontinuation of anti-Programmed-Death 1 (PD1) therapy without disease progression. 2018 ASCO Annual Meeting, 2018. e-Pub 2018.
      61. Peng W, Chunyu X, Melendez B, Jackson H, McKenzi JA, Williams LJ, Chen Y, Mbofung RM, Leahey SE, Lizee G, Davies MA, Yanamandra N, Hwu P. OX40 agonist antibody-based combination therapy with PI3Kβ selective inhibitor enhances T cell immunity. AACR Annual Meeting 2018, 2018. e-Pub 2018.
      62. de Macedo PM, Wang F, Marzese DM, Hudges CW, Wani K, Haydu LE, Danaher P, Merritt C, Ong G, Warren S, Beechem JM, Hoon DSB, Peng W, Kwong L, Tetzlaff MT, Lazar AJ, Davies MA. In-depth Molecular and Immune Characterization of Melanomas with Heterogeneous PTEN Expression. Society of Immunotherapy of Cancer, 2017. e-Pub 2017.
      63. de Macedo MP, Wang F, Marzese DM, Hudgens CW, Wani K, Siroy AE, Haydu LE, Danaher P, Merritt C, Ong G, Warren S, Beechem JM, Hoon DSB, Peng W, Tetzlaff M, Lazar A, Davies MA. In-depth molecular and immune characterization of melanoma with heterogeneous PTEN expression. World Congress for Melanoma, 2017. e-Pub 2017.
      64. Schadendorf D, Long GV Grog JJ, Nathan P, Ribas A, Davies MA, Flaherty KT, Squires M, Jaeger S, Powell W, Tan P Robert C. PD-L1 and CD8 expression and association with outcomes in patients (pts) with BRAF V600E/K–mutant metastatic melanoma (MM) who received dabrafenib + trametinib (D+T) in the randomized phase 3 COMBI-v study. ASCO Annual Meeting 2017, 2017. e-Pub 2017.
      65. Davies MA, Robert C, Long GV, Grob JJ, Flaherty KT, Arance A, Sileni-Chiarion V, Thomas L, Lesimple T, Mortier L, Moschos S, Hogg D, Rodas IM, Del Vecchio M, Lebbe C, Meyer N, Zhang Y, Huang Y, Mookerjee B, Saiag P. COMBI-MB: a phase 2 study of combination dabrafenib (D) and trametinib (T) in patients (pts) with BRAF V600–mutant (mut) melanoma brain metastases (MBM). 2017 ASCO Annual Meeting, 2017. e-Pub 2017.
      66. Chen WS, Andrews MC, Spencer C, Tawbi HAH, Lazar A, Tetzlaff MT, Patel SP, Hwu P, Hwu WJ, Diab A, Glitza IC, Amaria RN, Burton EM, Woodman SE, Davies MA, Gershenwald JE, Sharma P, Allison JP, Futreal A, Wargo JA. Molecular and immune predictors of response and toxicity to combined CTLA-4 and PD-1 blockade in metastatic melanoma (MM) patients (pts). ASCO Annual Meeting 2017, 2017. e-Pub 2017.
      67. Janku F, De Groot JF, Javle MM, Prado-Penas M, Shroff RT, Luthra R, Banks K, Lanman RB, Conley AP, Broaddus R, Davies MA, Kopetz S, Yung WKA, Heymach J, Fu S, Shaw KR, Meric-Bernstam F. Simultaneous molecular alterations in solid tumors with IDH1 or IDH2 mutations. ASCO Annual Meeting 2017, 2017. e-Pub 2017.
      68. Wargo JA, Gopalakrishnan V, Spencer C, Karpinets T, Reuben A, Andrews MC, Tetzlaff MT, Lazar M, Hwu P, Hwu WJ, Glitza IC, Tawbi HAH, Patel SP, Lee JE, Davies MA, Gershenwald JE, Futreal A, Sharma P, Allison JP, Jenq RR. Diversity and composition of the gut microbiome are associated with enhanced responses and improved progression-free survival (PFS) in metastatic melanoma (MM) patients (pts) on anti-PD-1 therapy. ASCO Annual Meeting 2017, 2017. e-Pub 2017.
      69. Wargo JA, Amaria RN, Prieto PA, Andrews MC, Tetzlaff MT, Futreal PA, Hwu P, Hwu WJ, Glitza IC, Tawbi HAH, Cormier JN, Lee JE, Patel SP, Simpson L, Burton EM, Jr BR, Ross MI, Gershenwald JE, Davies MA, Woodman SE. Treatment with neoadjuvant and adjuvant dabrafenib + trametinib (D+T) compared to standard-of-care (SOC) surgery and to identify targets to enhance responses in patients (pts) with high-risk resectable BRAF-mutant metastatic melanoma. ASCO Annual Meeting 2017, 2017. e-Pub 2017.
      70. McKean MA, Haydu LE, Ma J, Jr BR, Hwu WJ, Patel, SP, Diab A, Glitza IC, Tawbi HAH, Wong MK, McQuade JL, Hwu P, Davies MA, Amaria RN. Prognostic factors for overall survival (OS) in metastatic melanoma (MM) treated with immune checkpoint inhibitors: A single institution study of 696 patients. ASCO Annual Meeting 2017, 2017. e-Pub 2017.
      71. Menzies AM, Rozeman EA, Amaria RN, Scolyer RA, Tetzlaff MT, Guminski A, Davies MA, Blank CU, Wargo JA, Long GV. Preliminary results from the international neoadjuvant melanoma consortium (INMC). ASCO Annual Meeting 2017, 2017. e-Pub 2017.
      72. Schvartsman G, Ma J, Jr BR, Haydu LE, Amaria RN, Hwu P, Hwu WJ, Diab A, Patel SP, Davies MA, Tawbi HAH. Incidence, patterns of progression and outcomes of melanoma brain metastasis (MBM) during programmed-death 1 inhibitor (PD1i) therapy. ASCO Annual Meeting 2017, 2017. e-Pub 2017.
      73. Patel SP, Glitza IC, Diab A, Amari RN, Davies MA, Hwu P, Tawbi HAH, Hwu WJ. The safety and early efficacy of high-dose ipilimumab (IPI) and the combination nivolumab plus ipilimumab (NIVO + IPI) in patients (pts) with uveal melanoma (UM). ASCO Annual Meeting 2017, 2017. e-Pub 2017.
      74. Teh, Jessica NIkbakht N, Purwin TJ, Chervoneva I, Davies MA, Aplin AA. In vivo E2F reporting on efficacious dosing schedule MEK plus CDK inhibition in melanoma. 2016 SMR Congress, 2016. e-Pub 2016.
      75. Long DV, FLaherty KT, Schadendorf D, Nathan P, Robert C, Ribas A, Davies MA, Lane S, Legos JJ, Mookerjee B, Grob JJ. Patients characteristics associated with >36-mo clinical benefit with combination dabrafenib and trametinib (D+T) in COMBI-d. 2016 SMR Congress, 2016. e-Pub 2016.
      76. McQuade JL, Wang DY, Rai R, Park J, Spencer C, McKean M, Beckermann K, Nahar K, Rubinstein S, Guminski A, Lo S, Sosman JA, Wargo JA, Daniel C, Long GV, Hwu P Hess K, Carlin MS, Menzies A, Johnson DB, Davies MA. High body mass index (BMI) is associated with improved clinical outcomes in metastatic melanoma patients treated with anti-PD1: differences by gender. 2016 SMR Congress, 2016. e-Pub 2016.
      77. Cheng H, Chua V, Purwin TJ, Terai M, Liao C Kageyama K, Davies MA, Sato T, Aplin AE. Co-targeting HGF0cMET signaling with MEK inhibitors in metastatic uveal melanoma. 2016 SMR Congress, 2016. e-Pub 2016.
      78. Capparelli, Purwin TJ, Davies MA, Aplin AE. Stromal neuregulin-1 modulates the response to MEK inhibitors in WT BRAF/WT NRAS (WT/WT) melanoma. 2016 SMR Congress, 2016. e-Pub 2016.
      79. Bindal S, Ferguson S, Davies MA, Haydu L, Basset R JR, McCutcheon I, Glitza IC. Leptomeningeal disease (LMD) from metastatic melanoma: a single institution experience and predictors of survival. 2016 SMR Congress, 2016. e-Pub 2016.
      80. Maria, RN, Prieto P, Tetzlaff M, Diab A, Patel S, Woodman SE, Hwu WJ, Glitza IC, Hwu P, Tawbi H, McQuade JL, Cormier J, Lucci A, Royal R, Lee J, Bassett R, Simpson L, Burton EM, Grimm EA, Reuben A, Spencer C, Gershenwald JE, Ross M, Davies MA, Wargo JA. Treatment with neoadjuvant + adjuvant dabrafenib and trametinib (D+T) is associated with imporoved relapse-free survival (RFS versus standard of care (SOC) therapy in ptients with high-risk resectable BRAF-mutant melanoma. 2016 SMR Congress, 2016. e-Pub 2016.
      81. Long GV, Flaherty KT, Schadendorf D, Nathan P, Robert C, Ribas A, Davies MA, Lane S, Legos J, Mookerjee B, Grob JJ. Patient Characteristics Associated With ≥ 36-month Clinical Benefit With Combination Dabrafenib and Trametinib in COMBI-d. ESMO 2016 Scientific, 2016. e-Pub 2016.
      82. Kim DW, Haydu LE, Joon A, Bassett RL, Siroy A, Tetzlaff MT, Lazar A, Woodman SE, Gershenwald JE, Davies MA. Pathological and clinical features of non-acral cutaneous melanoma (CM) patients (pts) with TP53 and BRAFnon-V600 (NonV600) mutations (muts). ASCO Annual Meeting 2016, 2016. e-Pub 2016.
      83. Menzies AM, Johnson DB, Ramanujam S, Atkinson V, Wond ANM, Parker JJ, McQuade JL Shoushtari AN, Tsai KK, Eroglu Z, Klein O, Hassel JC, Sosman JA, Guminski A, Sullivan RJ, Ribas A, Carlin MS, Davies MA, Sandhu SK, Long GV. Anti-PD-1 therapy in patients with advanced melanoma and preexisting autoimmune disorders (AD) or major toxicity with ipilimumab (IPI). ASCO Annual Meeting 2016, 2016. e-Pub 2016.
      84. Barcena E, Trinh V, McIntyre SE, Simien R, Cain S, Diab A, Amaria RN, Patel SP, Glitza IC, Tawbi HAH, Davies MA, Hwu WJ. Responses in patients with BRAF V600-mutant metastatic melanoma receiving anti-PD1/PDL1 therapy alone or combined with BRAF inhibitors. ASCO Annual Meeting 2016, 2016. e-Pub 2016.
      85. Shaw AC, Trinh V, Bassett RL, Glitza IC, Diab A, Amaria RN, Tawbi HAH, Davies MA, Hwu WJ, Hwu P, Patel SP. Retrospective analysis of safety and efficacy of ipilimumab in elderly patients with advanced melanoma. ASCO Annual Meeting 2016, 2016. e-Pub 2016.
      86. Flaherty K, Davies MA, Grob JJ, Long DV, Nathan PD, Ribas A, Robert C, Schadendorf D, Frederick DT, Hammond MR, Valbuena-Jane J, Mu XJ, Squires M, Jaeger SA, Lane ST, Mookerjee B, Garraway LA. Genomic analysis and 3-y efficacy and safety update of COMBI-d: A phase 3 study of dabrafenib (D) + trametinib (T) vs D monotherapy in patients (pts) with unresectable or metastatic BRAF V600E/K-mutant cutaneous melanoma. ASCO Annual Meeting 2016, 2016. e-Pub 2016.
      87. Sullivan RJ, Barbash Z, Edelheit O, Vidne M, Sosman JA, Flaherty K, Davies MA, Johnson DB, Tarcic G. Functional characterization of non-V600 BRAF mutations and their response to Trametinib (Tram). ASCO Annual Meeting 2016, 2016. e-Pub 2016.
      88. Amaria RN, Haymaker CL, Bernatchez C, Forget MA, Patel V, Hwu WJ, Davies MA, Patel SP, Diab A, Glitza IC, Tawbi HAH, Woodman SE, Wargo JA, Ross MI, Lee JE, Gershenwald JE, Cormier JN, Royal RE, Lucci A, Hwu P. A phase I/II study of lymphodepletion plus adoptive cell transfer (ACT) with T cells transduced with CXCR2 and NGFR followed by high dose interleukin-2 (IL-2) in patients with metastatic melanoma (MM). ASCO Annual Meeting 2016, 2016. e-Pub 2016.
      89. Grob JJ, Flaherty K, Long GV, Nathan PD, Schadendorf D, Ribas A, Robert C, Lane SR, Mak C, Legenne P, Davies MA. Pooled analysis of safety over time and link between adverse events and efficacy across combination dabrafenib and trametinib (D+T) registration trials. ASCO Annual Meeting 2016, 2016. e-Pub 2016.
      90. Rohlfs, M, Bassett RL, Lacey C, McQual N, Mehta U, John I, Simien R, Tupue S, Dett TK, Glitza IC, Diab A, Amaria RN, Tawbi HAH, Davies MA, Hwu WJ, Hwu P, Patel SP. BRAF with or without MEK inhibition plus PD-1 checkpoint blockade for the treatment of metastatic melanoma. ASCO Annual Meeting 2016, 2016. e-Pub 2016.
      91. McQuade JL, Haydu LE, Frankian S, Spencer C, Long GV, Brob JJ, Lane SR, Legenne P, Flaherty K, Hwu P, Hess KR, Davies MA. The impact of obesity on outcomes in metastatic melanoma (MM) patients (pts) treated with dabrafenib and trametinib. ASCO Annual Meeting 2016, 2016. e-Pub 2016.
      92. Wargo JA, Amaria RN, Ross MI, Saw RPM, Gershenwald JE, Hwu P, Patel SP, Glitza IC, Diab A, Kefford R, Scolyer RA, Rizos H, Thompson JF, Shannon K, Spillane A, Carlino MS, Guminski A, Simpson L, Davies MA, Long GV. Neoadjuvant BRAF (dabrafenib) and MEK (trametinib) inhibition for high-risk resectable stage III and IV melanoma. ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      93. Amaria RN, Bassett RL, Simpson L, Delaney F, Hwu P, Kim K, Hwu WJ, Patel SP, Glitza IC, Davies MA, Woodman SE, Yee C, Bedikian AY. Phase I study of ipilimumab (IPI) with biochemotherapy (BCT) for chemonaïve patients with metastatic melanoma (MM). ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      94. Diab A, Martin A, Simpson L, Algazi AP, Chawla P, Kim DW, Santra S, Patel V, Jadhav N, Abhyankar D, Davies MA, Buch SC, Kim K, Daud A. Phase I trial of the CDK 4/6 inhibitor, P1446A-05 (voruciclib) in combination with the BRAF inhibitor (BRAFi), vemurafenib in advanced, BRAF-mutant melanoma. ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      95. McQuade JL, Chen G, Panka DJ, Reuben A, Bassett RL, Joon A, Lazar AJF, Tetzlaff MT, Simpson L, Mouton R, Patel SP, Glitza IC, Hwu WJ, Amaria RN, Diab A, Hwu P, Wargo JA, Sullivan RJ, Kim K, Davies MA. Phase II study of dabrafenib and trametinib following progression on BRAF inhibitor monotherapy in metastaticmelanoma: Exploration of clinical and molecular predictors of response. ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      96. Meric-Bernstam F, Brusco L, Daniels MS, Strong LC, Shaw KR, Lu KH, Qi Y, Lara-Guerra H, Litton JK, Zhao H, Eterovic AK, Arun B, Routbort M, Janku F, Davies MA, Kopetz S, Mendelsohn J, Mills GB, Chen K. Prevalence of incidental actionable germline mutations in 1,000 advanced cancer patients on a prospective somatic genomic profiling program. ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      97. Amaria RN, Wargo JA, Cooper ZA, Tetzlaff MT, Reuben A, Davies MA, Gershenwald JE, Jiang H, Austin-Breneman J, Lee JE, Hwu P, Hwu WJ, Cormier JN, Royal RE, Lucci A, Patel SP, Diab A, Glitza IC, Burton EM, Ross MI. Treatment with neoadjuvant BRAF Inhibition Yields Responses in Patients (pts) with High Risk Borderline Resectable Stage III Melanoma. ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      98. Bedard PL, Davies MA, Kopetz S, Flaherty KT, Shapiro G, Luke JJ, Spreafico A, Wu B, Gomez C, Cartot-Cotton S, Mazuir F, Micallef S, Demers B, Juric D. First-in-human phase I trial of the PI3Kb-selective inhibitor SAR260301 in patients with advanced solid tumors (NCT01673737). ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      99. Davies MA, Joon A, Bassett RL, Roszik J, Siroy A, Haydu LE, Chen K, Stingo F, Baladandayuthapani V, Shaw KR, Meric-Bernstam F, Tetzlaff MT, Gershenwald JE, Woodman SE, Lazar AJF. Demographics, tumor characteristics, and clinical outcomes associated with somatic mutations in 201 cancer-related genes in advanced melanoma patients (pts). ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      100. Haydu LE, Calderone TL, Miller J, Bassett RL, Joon A, Zhang J, Morgan MB, Shaw KR, Cooper ZA, Burton EM, Siroy A, Wani KM, Stingo F, Baladandayuthapani V, Tetzlaff MT, Wargo JA, Lazar AJF, Davies MA, Gershenwald JE. Comparison of DNA and RNA analyte extraction and melanin removal methods from formalin-fixed parraffin-embedded (FFPE) melanoma. ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      101. Roszik J, Joon A, Siroy A, Haydu LE, Stingo F, Baladandayuthapani V, Hwu P, Tetzlaff MT, Wargo JA, Chen JQ, Laszlo GR, Bernatchez C, Gershenwald JE, Lazar AJF, Davies MA, Woodman SE. A novel algorithm applicable to cancer next-generation sequencing panels to predict total tumor mutation load and correlation with clinical outcomes in melanoma. ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      102. Oba J, Wang WL, Eterovic AK, Stephan CC, Roszik J, Kale CR, Haymaker CL, Routbort M, Haydu LE, Bernatchez C, Davies MA, Lazar AJF, Grimm EA, Woodman SE. A global genomic and small molecule inhibitor interrogation of KIT mutant melanoma to reveal underlying biology and novel molecular targets. ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      103. Patel SP, L S, Rohlfs ML, Fox PS, Richard J, Iqbal M, Bernzen T, Glitza IC, Papdopoulos NE, Hwu P, Davies MA. BRAF and NRAS mutations in Metastatic Melanoma Patients with Leptomeningeal Disease. ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      104. Kemnade J, Roszik J, Joon A, Stingo F, Baladandayuthapani V, Lazar AJF, Woodman SE, Davies MA. Identification of potentially actionable mutations in RTKs in melanoma detected by next generation sequencing (NGS). ASCO Annual Meeting 2015, 2015. e-Pub 2015.
      105. Joon A, Haydu L, Baladandayuthapani V, Stingo F, Woodman S, Amaria A, Wargo J, shaw K, Meric-Bernstam F, Mills G, Gershenwald J, Hwu P, a L, Davies MA. Next generation sequencing of 201 cancer-related genes in melanoma. Society for Melanoma Research 2014 Congress, 2014. e-Pub 2014.
      106. Yan Jiang, Farias, R., Holly, A, E., Levy, E. J., Klein, L., Rains, J., Sirmans, E., Burton, E. M., Wang, Amaria, R. N, Davies, M. A., Glitza, I. C., Patel, S. P., Diab, A., Tawbi, H. A., Wong, M. K. K., Ikeguchi, A., Wargo, J. A, Daniel-MacDougall, C., McQuade, J. L.. The DIET study: A randomized controlled trial of a high fiber diet intervention (HFDI) in melanoma patients (pts) receiving immune checkpoint blockade (ICB).
      107. Afsaneh Amouzegar, Merve Hasanov, Ahmed Ali, Denái R Milton, Julie M Simon, Jene Samuels, Khalida M Wani, Debora Ledesma, Elizabeth Burton, Courtney W. Hudgens, Hussein Tawbi, Jeffrey E. Gershenwald, Alexander J. Lazar, Davies MA. Association of KIT mutations with risk of central nervous system (CNS) metastasis (met) in patients (pts) with mucosal melanoma (MM). ASCO Annual Meeting 2025.

      Book Chapters

      1. Hasanov, M, Acikgoz, Y, Davies, MA. Melanoma Brain Metastasis. In: Hematology/Oncology Clinics of North America, 1027-1043, 2024.
      2. Safa H, Mattei J, Bishop AJ, Keung EZ, Yadugiri S, Davies MA, Glitza IC. Melanoma. In: The MD Anderson Manual of Medical Oncology. 4. McGraw Hill, 2022.
      3. Margolin K, Davies MA, Kluger H, Tawbi H. Melanoma Brain Metastases: Unique Biology and Implications for Systemic Therapy. In: Cutaneous Melanoma. 6th. Springer, Cham, 1-34, 2019.
      4. Fischer GM, Davies MA. Melanoma Brain Metastasis: Insights, Progress Challenges, and Opportunities. In: Melanoma. Springer, 1-21, 2019.
      5. Glitza IC, Heimberger AB, Sulman EP, Davies MA. Prognostic factors for survival in melanoma patients with brain. In: Brain Metastases from Primary Tumors. Academic Press, 267-297, 2016.
      6. Siroy AE, Davies MA, Lazar AJ. The PI3K-AKT Pathway in Melanoma. In: Genetics of Melanoma. Cancer Genetics, 165-180, 2016.
      7. Davies MA, Garraway LA. Molecular Biology of Cutaneous Melanoma. In: Cancer: Principles and Practice of Oncology. Primer of the molecular biology of cancer. 2nd edition. Wolters Kluwer, 308 - 320, 2015.
      8. Davies MA. Parallel and Serial Blockade Strategies in BRAF-Mutant Melanoma. In: BRAF Targets in Melanoma. Humana Press, 105.135, 2015.
      9. Davies MA, Garraway LA. Molecular Biology of Cutaneous Melanoma. In: Cancer Principles & Practice of Oncology. 10th. Wolters Kluwer, 1337-1345, 2015.
      10. Kupferman ME, Davies MA. Melanoma of the Head and Neck: General Principles and Management. In: Head and Neck Cancer A Multidisciplinary Approach. 4th. Wolters Kluwer Lippincott Williams & Wilkins, 672-691, 2013.
      11. Ahmed KB, Davies MA. New Molecular Targets for Systemic Therapy of Melanoma. In: Research on Melanoma - A Glimpse into Current Directions and Future Trends. InTech - Open Access Publisher, 161-180, 2011.
      12. Kim KB, Davies MA, Rapini RP, Hwu P, Bedikian AY. Malignant Melanoma. In: The MD Anderson Manual of Medical Oncology, Second Edition. 2nd. McGraw Hill, 1077-1109, 2011.
      13. Davies MA, Patel S, Kim K. Targeted Therapy in Melanoma. In: Targeted Therapy in Cancer. 1. Humana Press, 183-211, 2008.
      14. Davies MA. PTEN, a tumor suppressor gene frequently mutated in glioblastomas. In: Genomic and Molecular Neuro-Oncology. Jones and Bartlett, 47-61, 2004.

      Letters to the Editor

      1. Paleker M, Davies MA, Raubenheimer P, Naude J, Boulle A, Hussey H. Change in profile of COVID-19 deaths in Western Cape Province, South Africa, during the fourth wave. S Afr Med J 112: 185-186, 2022.
      2. Schomaker M, Davies MA, Cornell M, Ford N. Assessing the risk of dolutegravir for women of childbearing potential. Lancet Glob Health 6: e958-e959, 2018.
      3. Davies MA, Saiag P, Long GV. Primary medical therapy for BRAF(V600E)-mutant melanoma brain metastases-is this good enough? - Authors' reply. Lancet Oncol 18: e509, 2017.
      4. Koller M, Patel K, Chi BH, Wools-Kaloustian K, Dicko F, Chokephaibulkit K, Chimbetete C, Hazra R, Ayaya S, Leroy V, Trong HK, Egger M, Davies MA. Authors' Reply: Early Initiation of Antiretroviral Therapy Among Young Children: A Long Way to Go. J Acquir Immune Defic Syndr 70: e71-2, 2015.
      5. Bohlius J, Maskew M, Davies MA, Egger M. HHV-8 seroprevalence in HIV-positive and HIV-negative populations. Int J Cancer 136: 1243, 2015.
      6. Koller M, Althoff KN, Davies MA, Egger M. Authors' reply: immunodeficiency at the start of combination antiretroviral therapy: steady improvement or step changes?. J Acquir Immune Defic Syndr 68: e16-7, 2015.
      7. Jilaveanu LB, Zito CR, Aziz SA, Chakraborty A, Davies MA, Camp RL, Rimm DL, Dudek A, Sznol M, Kluger HM. In vitro studies of dasatinib, its targets and predictors of sensitivity. Pigment Cell Melanoma Res 24: 386-9, 2011.
      8. Munetz MR, Davies MA. Smoking by patients. Hosp Community Psychiatry 38: 413-4, 1987.
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