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Monica E. Loghin, M. D.

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Neuro-Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Residency Program Director, Department of Neuro-Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Assistant Professor, Department of Neurology, The University of Texas Medical Branch, Galveston, TX

Bio Statement

Dr. Loghin is an Assistant Professor of Neuro-Oncology at M. D. Anderson Cancer Center.  She completed her neurology residency training at University of Texas Health Science Center and thereafter she was accepted and completed a Neuro-Oncology fellowship at MD Anderson Cancer Center.  Dr. Loghin is involved in patient clinical care as well as in the training program for Neuro-Oncology fellows and neurology residents. She currently serves as the Department of Neuro-Oncology Residency Program Director, dedicating a lot of effort and energy in developing a competitive and high quality teaching program.

Research Interests

Dr. Loghin's research interests are focused on neurological complications related to cancer treatment, particularly neurological and cognitive deficits induced by radiation therapy. She is collaborating closely with the Neuropschylogy Section in developing new therapeutic strategies  for cancer related cognitive dysfunction.

Office Address

The University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd.
Unit Number: 431
Houston, TX 77030
Phone: 713-745-4098
Fax: 713-794-4999
Email: mloghin@mdanderson.org

Education & Training

Degree-Granting Education

1983 "Gr.T. Popa" University of Medicine and Pharmacy, Iasi, Romania, MD, Medicine

Postgraduate Training

12/2003-11/2005 Clinical Fellowship, Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Dr. Vinay Puduvalli
12/2000-11/2003 Clinical Residency, Neurology, UT Health Science Center, Houston, TX, Dr. Maya Schiess
12/1999-11/2000 Clinical Residency, Internal Medicine, UT Health Science Center, Houston, TX, Dr. Mark Farnie

Board Certifications

2005 The American Board of Psychiatry & Neurology
1992 The Romanian Board of Neurology

Honors and Awards

2012 Nominated for Gerald P. Bodey Award for Excellence in Education, University of Texas MD Anderson Cancer Center

Selected Publications

Peer-Reviewed Original Research Articles

1. Loghin ME, Groves M, Garciarena P,. Glioblastoma: Molecular biology and its impact on personalized treatment. Expert Review of Neurotherapeutics. In Press.
2. Giglio P, Dhamne M, Hess KR, Gilbert MR, Groves MD, Levin VA, Kang SL, Ictech SE, Liu V, Colman H, Conrad CA, Loghin M, de Groot J, Yung WK, Puduvalli VK. Phase 2 trial of irinotecan and thalidomide in adults with recurrent anaplastic glioma. Cancer. e-Pub 11/2011. PMID: 22086614.
3. Levin VA, Bidaut L, Hou P, Kumar AJ, Wefel JS, Bekele BN, Prabhu S, Loghin M, Gilbert MR, Jackson EF. Randomized Double-Blind Placebo-Controlled Trial of Bevacizumab Therapy for Radiation Necrosis of the Central Nervous System. Int J Radiat Oncol Biol Phys 79(5):1487-95, 4/2011. e-Pub 4/2010. PMCID: PMC2908725.
4. Loghin M, Prados M, Wen P, Junck L, Lieberman F, Fine H, Fink K, Mehta M, Kuhn J, Lamborn K, Chang S, Cloughesy T, DeAngelis L, Robins HI, Aldape K, Yung, WKA. Phase I study of Temozolomide and Irinotecan for recurrent malignant gliomas in patients receiving enzyme-inducing antiepileptic drugs: A North American Brain Tumor Consortium study. Clin Cancer Res 13(23):7133-7138, 12/2007. PMID: 18056194.
5. Radu A, Alecu CS, Raclariu A, Nanu L, Loghin M, Stanciu E, Necula A, Ionescu-Tirgoviste C, Patrugan V. CompAc information system for traditional Chinese medicine. Stud Health Technol Inform 81:401-3, 2001. PMID: 11317777.
6. Loghin M, Prodan R, Stefanache F. The role of evoked potentials in the diagnosis of posterior fossa tumors. Acta Neurologica Moldavica, 1994.
7. Pendefunda G, Prodan R, Loghin M. Cerebral hemorrhage in blood disorders. Journal of the Society of Physicians and Nature Scientists, 1989.

Invited Articles

1. Vaillant B, Loghin M. Treatment of spinal cord tumors. Curr Treat Options Neurol 11(4):315-24, 7/2009. e-Pub 6/2009. PMID: 19523357.
2. Penas-Prado M, Loghin M. Spinal cord compression in cancer patients: Review of diagnosis and treatment. Curr Oncol Rep 10(1):78-85, 1/2008. PMID: 18366964.
3. Loghin M, Levin VA. Headache related to brain tumors. Curr Treat Options Neurol 8(1):21-32, 1/2006. PMID: 16343358.
4. Gilbert MR, Loghin M. The Treatment of Malignant Gliomas. Curr Treat Options Neurol 7(4):293-303, 7/2005. PMID: 15967092.

Abstracts

1. Zohrevand P, Loghin M. Transient Leukoencephalopathy after Intrathecal Chemotherapy Mimicking Stroke. Neurology. In Proceedings: American Academy of Neurology (AAN) meeting, New Orleans LA 4/24-4/27/2012 78 (#PO6.015), 4/2012.
2. Colman H, Gilbert M, Yung WKA, Aldape K, deGroot J, Conrad C, Levin V, Groves M, Loghin M, Pelloski C, Puduvalli V. A phase I study of Sorafen1B with radiation and temozolomide in newly diagnosed glioblastoma. Neuro-Oncology. Proceedings In: 16th Annual Meeting of the Society for Neuro-Oncology, Orange County, CA, November 17 - November 20, 2011 13(Supplemement 3):iii61 (#NO-89), 11/2011.
3. Groves MD, DeGroot J, Loghin M, Conrad C, Hess K, Ictech S, Hunter K, Yung WKA. A phase I study of Temozolomide and Intrathecal Liposomal Cytarabine in patients with neuroplastic meningitis. Neuro-Oncology. Proceedings In: 16th Annual Meeting of the Society for Neuro-Oncology, Orange County, CA, November 17 - November 20, 2011 13(Supplement 3):iii43 (#NO-11), 11/2011.
4. Hamilton JD, Levin VA, Hou P, Prabhu S, Loghin ME, Gilbert MR, Bassett RL, Wang J. Advanced MR imaging shows decreased vessel leakiness/edema and may predict complications in Bevacizumab therapy of brain radiation necrosis. Neuro-Oncology. Proceedings In: 16th Annual Meeting of the Society for Neuro-Oncology, Orange County, CA, November 17 - November 20, 2011 13(Supplement 3):iii142 (#RA-28), 11/2011.
5. Hamilton JD, Wang J, Levin VA, Hou P, Loghin ME, Gilbert MR, Leeds NE, deGroot, JF, Puduvalli V, Jackson EF, Yung WKA, Kumar AJ. Normalized baseline ADC values predict problems associated with Bevacizumab treatment for glioblastoma multiforme or brain radiation induced necrosis. Neuro-Oncology. Proceedings In: 16th Annual Meeting of the Society for Neuro-Oncology, Orange County, CA, November 17 - November 20, 2011 13(Supplement 3):iii137 (#RA04), 11/2011.
6. Paker AM, Chi L, Kamiya-Matsuoka C, Loghin ME. Posterior reversible encephalopathy syndrome in cancer patients. Neurology. In Proceedings: 16 Annual Scientific Meeting of the Society for Neuro-Oncology, Orange County, CA, November 17-20, 2011 78 (#PO6.015), 11/2011.
7. Paker AM, Chi L, Ruiz MD, Loghin ME. Posterior reversible encephalopathy syndrome in patients with cancer. J Clin Oncol 29: 2011 (suppl; abstr 2561). In Proceedings: 2011 Annual American Society of Clinical Oncology (ASCO), Chicago IL, June 4-7, 2011 29 (#2561), 6/2011.
8. Puduvalli VK, Penas-Prado M, Gilbert MR, Groves MD, Hess KR, Levin VA, de Groot J, Colman H, Conrad CA, Loghin ME, Hunter K, Yung WKA. Phase I study of Vorinostat combined with Isotretinoin and Carboplatin in Adults with Recurrent Malignant Gliomas. Neuro-Oncology: In proceedings of the 2010 Annual Meeting of the Society for Neuro-Oncology (SNO), Montreal, Canada, November 18 - November 21, 2010 (#OT-02), 11/2010.
9. Loghin M, Groves M. Neoplastic meningitis in unknown primary neoplasms. Journal of Clinical Oncology. In: 2006 ASCO Annual Meeting Proceedings, 2006, Atlanta Georgia 24(18-S) (#11517), 6/2006.

Grant & Contract Support

Title: Phase III Double Blind, Placebo Controlled Study of Donepezil in Irradiated Brain Tumor Patients
Funding Source: NIH/NCI
Role: Principal Investigator-MDACC
Duration: 4/1/2007 - 3/31/2011

Last updated: 12/19/2012