Pablo C. Okhuysen, M.D., FACP, FIDSA

Peer-Reviewed Articles

1. Peña, JA, Mazhuvanchery, C, Nascimento Santos, MM, Naz, S, Cruz, CC, Wali, S, Varatharajalu, K, Okhuysen, PC, Vuong, NN, Wang, Y. Bezlotoxumab for the prevention of recurrent Clostridioides difficile infection for patients with cancer. Annals of Gastroenterology 38(5):519-525, 2025. e-Pub 2025. PMID: 40937050.
2. Shatila, M, Abdul-baki, K, Urias Rivera, AC, Takigawa, K, Lee, IA, Sullivan, A, Gupta, T, Lu, L, Menon, R, Khan, A, Salim, H, Baerman, E, Cruz, CC, Natha, C, Vemulapalli, V, Coleman, G, Varatharajalu, K, Fan, C, Okhuysen, PC, Olszanski, AJ, Zhou, Y, Zhang, HC, Shafi, MA, Wang, Y. Gastrointestinal Infection Before Immune Checkpoint Inhibition Hinders Treatment Efficacy and Increases the Risk of Colitis. Cancer medicine 14(15), 2025. e-Pub 2025. PMID: 40785196.
3. Aleem A, Sarihan MC, Okhuysen PC, Roeland EJ, Schwartzberg L, Wang Y, Chaturvedi P. The impact of cancer-related diarrhea on changes in cancer therapy. Support Care Cancer 32(10):668, 2024. e-Pub 2024. PMID: 39287693.
4. Hayase E, Hayase T, Mukherjee A, Stinson SC, Jamal MA, Ortega MR, Sanchez CA, Ahmed SS, Karmouch JL, Chang CC, Flores II, McDaniel LK, Brown AN, El-Himri RK, Chapa VA, Tan L, Tran BQ, Xiao Y, Fan C, Pham D, Halsey TM, Jin Y, Tsai WB, Prasad R, Glover IK, Enkhbayar A, Mohammed A, Schmiester M, King KY, Britton RA, Reddy P, Wong MC, Ajami NJ, Wargo JA, Shelburne S, Okhuysen PC, Liu C, Fowler SW, Conner ME, Katsamakis Z, Smith N, Burgos da Silva M, Ponce DM, Peled JU, van den Brink MRM, Peterson CB, Rondon G, Molldrem JJ, Champlin RE, Shpall EJ, Lorenzi PL, Mehta RS, Martens EC, Alousi AM, Jenq RR. Bacteroides ovatus alleviates dysbiotic microbiota-induced graft-versus-host disease. Cell Host Microbe 32(9):1621-1636.e6, 2024. e-Pub 2024. PMID: 39214085.
5. Okhuysen PC, Ramesh MS, Louie T, Kiknadze N, Torre-Cisneros J, de Oliveira CM, Van Steenkiste C, Stychneuskaya A, Garey KW, Garcia-Diaz J, Li J, Duperchy E, Chang BY, Sukbuntherng J, Montoya JG, Styles L, Clow F, James D, Dubberke ER, Wilcox M. A Randomized, Double-Blind, Phase 3 Safety and Efficacy Study of Ridinilazole Versus Vancomycin for Treatment of Clostridioides difficile Infection: Clinical Outcomes With Microbiome and Metabolome Correlates of Response. Clin Infect Dis 78(6):1462-1472, 2024. e-Pub 2024. PMID: 38305378.
6. Chappell CL, Hoffman KL, Lorenzi PL, Tan L, Petrosino J, Gibbs R, Muzny D, Doddapaneni H, Ross MC, Menon VK, Surathu A, Javornik Cregeen SJ, Reyes AG, Okhuysen PC. Tryptophan Metabolites And Their Predicted Microbial Sources In Fecal Samples From Healthy Individuals. bioRxiv, 2024. e-Pub 2024. PMID: 38187744.
7. Murphy, BR, Dailey Garnes, NM, Hwang, H, Peterson, CB, Garey, K, Okhuysen, PC. Increased Prevalence of Clostridioides difficile Infection among Pediatric Oncology Patients. Pediatric Infectious Disease Journal 43(2):136-141, 2024. e-Pub 2024. PMID: 38134390.
8. Zhang, X, Irajizad, E, Hoffman, KL, Fahrmann, JF, Li, F, Seo, YD, Browman, G, Dennison, JB, Vykoukal, JV, Luna, PN, Siu, W, Wu, R, Murage, EN, Ajami, NJ, McQuade, JL, Wargo, J, Long, JP, Do, K, Lampe, JW, Basen-Engquist, KM, Okhuysen, PC, Kopetz, S, Hanash, S, Petrosino, JF, Scheet, PA, Daniel-MacDougall, CR. Modulating a prebiotic food source influences inflammation and immune-regulating gut microbes and metabolites. EBioMedicine 98, 2023. e-Pub 2023. PMID: 38040541.
9. Colbert, LE, El Alam, MB, Wang, R, Karpinets, T, Lo, DK, Lynn, EJ, Harris, TA, Elnaggar, JH, Yoshida-Court, K, Tomasic, KC, Bronk, JK, Sammouri, J, Yanamandra, AV, Olvera, AV, Carlin, LG, Sims, TT, Delgado Medrano, AY, Napravnik, TC, O'Hara, MP, Lin, D, Abana, CO, Li, HX, Eifel, PJ, Jhingran, A, Joyner, MM, Lin, L, Ramondetta, LM, Futreal, A, Schmeler, KM, Mathew, GG, Dorta-Estremera, S, Zhang, J, Wu, X, Ajami, NJ, Wong, MC, Taniguchi, C, Petrosino, JF, Sastry, KJ, Okhuysen, PC, Martinez, SA, Tan, L, Mahmud, I, Lorenzi, PL, Wargo, J, Klopp, AH. Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring. Cancer cell 41(11):1945-1962.e11, 2023. e-Pub 2023. PMID: 37863066.
10. Liu C, Amin R, Shatila M, Short N, Altan M, Shah A, Alhalabi O, Okhuysen PC, Thomas AS, Wang Y. Clinical characteristics and outcomes of tyrosine kinase inhibitor-related lower GI adverse effects. J Cancer Res Clin Oncol 149(7):3965-3976, 2023. e-Pub 2022. PMID: 36030431.
11. Carter H, Clark J, Carlin LG, Vaughan E, Rajan A, Olvera A, Yu X, Zeng XL, Kambal A, Holder M, Qin X, Gibbs RA, Petrosino JF, Muzny DM, Doddapaneni H, Menon VK, Hoffman KL, Meng Q, Ross MC, Javornik Cregeen SJ, Metcalf G, Jenq R, Blutt S, Estes MK, Maresso A, Okhuysen PC. Functional Genomics of Gastrointestinal Escherichia coli Isolated from Patients with Cancer and Diarrhea. bioRxiv, 2023. e-Pub 2023. PMID: 37398483.
12. Francisco DMA, Zhang L, Jiang Y, Olvera A, Adachi J, Guevara EY, Aitken SL, Garey KW, Peterson CB, Do KA, Dillon R, Obi EN, Jenq R, Okhuysen PC. Risk Factors Associated with Severe Clostridioides difficile Infection in Patients with Cancer. Infect Dis Ther 12(1):209-225, 2023. e-Pub 2023. PMID: 36443547.
13. Schwabkey ZI, Wiesnoski DH, Chang CC, Tsai WB, Pham D, Ahmed SS, Hayase T, Ortega Turrubiates MR, El-Himri RK, Sanchez CA, Hayase E, Frenk Oquendo AC, Miyama T, Halsey TM, Heckel BE, Brown AN, Jin Y, Raybaud M, Prasad R, Flores I, McDaniel L, Chapa V, Lorenzi PL, Warmoes MO, Tan L, Swennes AG, Fowler S, Conner M, McHugh K, Graf T, Jensen VB, Peterson CB, Do KA, Zhang L, Shi Y, Wang Y, Galloway-Pena JR, Okhuysen PC, Daniel-MacDougall CR, Shono Y, Burgos da Silva M, Peled JU, van den Brink MRM, Ajami N, Wargo JA, Reddy P, Valdivia RH, Davey L, Rondon G, Srour SA, Mehta RS, Alousi AM, Shpall EJ, Champlin RE, Shelburne SA, Molldrem JJ, Jamal MA, Karmouch JL, Jenq RR. Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment. Sci Transl Med 16(14):eabo3445, 2022. e-Pub 2022. PMID: 36383683.
14. Gudiol C, Hicklen RS, Okhyusen PC, Malek AE, Kontoyiannis DP. Infections simulating immune checkpoint inhibitor toxicities: Uncommon and deceptive. Open Forum Infectious Diseases, 2022. e-Pub 2022. PMID: 36420059.
15. Karpinets TV, Wu X, Solley T, El Alam MB, Sims TT, Yoshida-Court K, Lynn E, Ahmed-Kaddar M, Biegert G, Yue J, Song X, Sun H, Petrosino JF, Mezzari MP, Okhuysen P, Eifel PJ, Jhingran A, Lin LL, Schmeler KM, Ramondetta L, Ajami N, Jenq RR, Futreal A, Zhang J, Klopp AH, Colbert LE. Metagenomes of rectal swabs in larger, advanced stage cervical cancers have enhanced mucus degrading functionalities and distinct taxonomic structure. BMC Cancer 22(1):945, 2022. e-Pub 2022. PMID: 36050658.
16. Menon VK, Okhuysen PC, Chappell CL, Mahmoud M, Mahmoud M, Meng Q, Doddapaneni H, Vee V, Han Y, Salvi S, Bhamidipati S, Kottapalli K, Weissenberger G, Shen H, Ross MC, Hoffman KL, Cregeen SJ, Muzny DM, Metcalf GA, Gibbs RA, Petrosino JF, Sedlazeck FJ. Fully resolved assembly of Cryptosporidium parvum. Gigascience 11, 2022. e-Pub 2022. PMID: 35166336.
17. Panneerselvam K, Szafron D, Amin RN, Wei D, Tan D, Altan M, Okhuysen PC, Shatila M, Raju GS, Thomas AS, Wang Y. Cytomegalovirus infection among patients with cancer receiving immune checkpoint inhibitors. Ann Gastroenterol 35(5):522-531, 2022. e-Pub 2022. PMID: 36061160.
18. Vasavada S, Panneerselvam K, Amin R, Varatharajalu K, Okhuysen PC, Oliva ICG, Wang J, Grivas P, Thomas AS, Wang Y. Clostridioides difficile infection in cancer patients receiving immune checkpoint inhibitors. Ann Gastroenterol 35(4):393-399, 2022. e-Pub 2022. PMID: 35784625.
19. Ma W, Gong Z, Abu-Sbeih H, Peng Y, Peng F, Zou F, Charabaty A, Okhuysen PC, McQuade JL, Altan M, Zhang HC, Thomas AS, Wang Y. Outcomes of Immune Checkpoint Inhibitor-Related Diarrhea or Colitis in Cancer Patients with Superimposed Gastrointestinal Infections. Am J Clin Oncol 44(8):402-408, 2021. e-Pub 2021. PMID: 34107499.
20. Viola GM, Malek AE, Rosen LB, DiNardo AR, Nishiguchi T, Okhuysen PC, Holland SM, Kontoyiannis DP. Disseminated cryptococcosis and anti-granulocyte-macrophage colony-stimulating factor autoantibodies: An underappreciated association. Mycoses 64(6):576-582, 2021. e-Pub 2021. PMID: 33476401.
21. Yepez Guevara EA, Aitken SL, Olvera AV, Carlin L, Fernandes KE, Bhatti MM, Garey KW, Adachi J, Okhuysen PC. Clostridioides difficile infection in cancer and immunocompromised patients: Relevance of a two-step diagnostic algorithm and infecting ribotypes on clinical outcomes. Clin Infect Dis 72(10):e460-e465, 2021. e-Pub 2021. PMID: 32803229.
22. Olvera A, Carter H, Rajan A, Carlin LG, Yu X, Zeng XL, Shelburne S, Bhatti M, Blutt SE, Shroyer NF, Jenq R, Estes MK, Maresso A, Okhuysen PC. Enteropathogenic Escherichia coli Infection in Cancer and Immunosuppressed Patients. Clin Infect Dis 18(72):e620-e629, 2021. e-Pub 2021. PMID: 32930708.
23. Gogia B, Young AL, O'Brien BJ, Okhuysen PC, Kumar VA. Bihemispheric Cortical Infarcts in an Adult Secondary to Escherichia coli K1 Meningitis. Case Rep Neurol 13(2):572-577, 2021. e-Pub 2021. PMID: 34720964.
24. Handley G, Hasbun R, Okhuysen P. Human herpesvirus 6 and central nervous system disease in oncology patients: A retrospective case series and literature review. J Clin Virol 136:104740, 2021. e-Pub 2021. PMID: 33548682.
25. Ali H, Khurana S, Ma W, Peng Y, Jiang ZD, DuPont H, Zhang HC, Thomas AS, Okhuysen PC, Wang Y. Safety and efficacy of fecal microbiota transplantation to treat and prevent recurrent Clostridioides difficile in cancer patients. J Cancer 12(21):6498-6506, 2021. e-Pub 2021. PMID: 34659541.
26. Chakravarti, D, Hu, B, Mao, X, Rashid, A, Li, J, Li, J, Liao, WT, Whitley, EM, Dey, P, Hou, P, LaBella, KA, Chang, A, Wang, G, Spring, DJ, Deng, P, Zhao, D, Liang, X, Lan, ZD, Lin, Y, Sarkar, S, Terranova, C, Lissanu Deribe, Y, Blutt, SE, Okhuysen, PC, Zhang, J, Vilar Sanchez, E, Nielsen, OH, Dupont, A, Younes, M, Patel, K, Shroyer, NF, Rai, K, Estes, MK, Wang, YA, Bertuch, AA, DePinho, RA. Telomere dysfunction activates YAP1 to drive tissue inflammation. Nature communications 11(1), 2020. e-Pub 2020. PMID: 32958778.
27. Rajan, A, Robertson, MJ, Carter, HE, Poole, NM, Clark, JR, Green, SI, Criss, ZK, Zhao, B, Karandikar, UC, Xing, Y, Margalef-Català, M, Jain, N, Wilson, RL, Bai, F, Hyser, JM, Petrosino, JF, Shroyer, NF, Blutt, SE, Coarfa, C, Song, X, Prasad, BV, Amieva, MR, Grande-Allen, J, Estes, MK, Okhuysen, PC, Maresso, AW. Enteroaggregative E. coli adherence to human heparan sulfate proteoglycans drives segment and host specific responses to infection. PLoS pathogens 16(9), 2020. e-Pub 2020. PMID: 32986782.
28. Gómez-Sandoval, JN, Okhuysen, PC, Mondragón-Flores, R, Escalona-Montaño, AR, Aguirre-García, MM. Cellular Identification and In Silico Characterization of Protein Phosphatase 2C (PP2C) of Cryptosporidium parvum. Acta Parasitologica 65(3):704-715, 2020. e-Pub 2020. PMID: 32347536.
29. Mitra A, Grossman Biegert GW, Delgado AY, Karpinets TV, Solley TN, Mezzari MP, Yoshida-Court K, Petrosino JF, Mikkelson MA, Lin L, Eifel P, Zhang J, Ramondetta LM, Jhingran A, Sims TT, Schmeler K, Okhuysen P, Colbert LE, Klopp AH. Microbial Diversity and Composition Is Associated with Patient-Reported Toxicity during Chemoradiation Therapy for Cervical Cancer. Int J Radiat Oncol Biol Phys 107(1):163-71, 2020. e-Pub 2020. PMID: 31987960.
30. Abu-Sbeih H, Ali FS, Chen E, Mallepally N, Luo W, Lu Y, Foo WC, Qiao W, Okhuysen PC, Adachi JA, Hachem RY, Altan M, Jenq RR, Wang Y. Neutropenic Enterocolitis: Clinical Features and Outcomes. Dis Colon Rectum 63(3):381-388, 2020. e-Pub 2019. PMID: 31842164.
31. Zhang X, Browman G, Siu W, Basen-Engquist KM, Hanash SM, Hoffman KL, Okhuysen PC, Scheet P, Petrosino JF, Kopetz S, Daniel CR. The BE GONE trial study protocol: a randomized crossover dietary intervention of dry beans targeting the gut microbiome of overweight and obese patients with a history of colorectal polyps or cancer. BMC Cancer 19(1):1233, 2019. e-Pub 2019. PMID: 31852462.
32. Abu-Sbeih H, Tang T, Ali FS, Luo W, Neelapu SS, Westin JR, Okhuysen PC, Foo WC, Curry JL, Richards DM, Ge PS, Wang Y. Gastrointestinal Adverse Events Observed After Chimeric Antigen Receptor T-Cell Therapy. Am J Clin Oncol 42(10):789-796, 2019. e-Pub 2019. PMID: 31478934.
33. Abu-Sbeih H, Herrera LN, Tang T, Altan M, Chaftari AP, Okhuysen PC, Jenq RR, Wang Y. Impact of antibiotic therapy on the development and response to treatment of immune checkpoint inhibitor-mediated diarrhea and colitis. J Immunother Cancer 7(1):242, 2019. e-Pub 2019. PMID: 31488205.
34. Galloway-Pena, J, Peterson, CB, Malik, FA, Sahasrabhojane, P, Shah, DJ, Brumlow, C, Carlin, LG, Chemaly, RF, Im, JS, Rondon, G, Felix, E, Veillon, L, Lorenzi, PL, Alousi, AM, Jenq, RR, Kontoyiannis, DP, Shpall, E, Shelburne, S, Okhuysen, PC. Fecal microbiome, metabolites, and stem cell transplant outcomes. Open Forum Infectious Diseases 6(5), 2019. e-Pub 2019. PMID: 31065565.
35. Wang, EW, Bhatti, MM, Cantu, S, Okhuysen, PC. Diagnosis of Yersinia enterocolitica infection in cancer patients with diarrhea in the era of molecular diagnostics for gastrointestinal infections. Open Forum Infectious Diseases 6(4), 2019. e-Pub 2019. PMID: 31049362.
36. Kuhlmann FM, Martin J, Hazen TH, Vickers TJ, Pashos M, Okhuysen PC, Gómez-Duarte OG, Cebelinski E, Boxrud D, Del Canto F, Vidal R, Qadri F, Mitreva M, Rasko DA, Fleckenstein JM. Conservation and global distribution of non-canonical antigens in Enterotoxigenic Escherichia coli. PLoS Negl Trop Dis 13(11):e0007825, 2019. e-Pub 2019. PMID: 31756188.
37. Abu-Sbeih H, Choi K, Tran CN, Wang X, Lum P, Shuttlesworth G, Stroehlein JR, Okhuysen PC, Wang Y. Recurrent Clostridium difficile infection is associated with treatment failure and prolonged illness in cancer patients. Eur J Gastroenterol Hepatol 31(1):128-134, 2019. e-Pub 2019. PMID: 30339561.
38. Yalamanchili H, Dandachi D, Okhuysen PC. Use and Interpretation of Enteropathogen Multiplex Nucleic Acid Amplification Tests in Patients With Suspected Infectious Diarrhea. Gastroenterol Hepatol (N Y) 14(11):646-652, 2018. e-Pub 2018. PMID: 30538605.
39. Rajan A, Vela L, Zeng XL, Yu X, Shroyer N, Blutt SE, Poole NM, Carlin LG, Nataro JP, Estes MK, Okhuysen PC, Maresso AW. Novel Segment- and Host-Specific Patterns of Enteroaggregative Escherichia coli Adherence to Human Intestinal Enteroids. MBio 9(1), 2018. e-Pub 2018. PMID: 29463660.
40. Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA. Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients. Science 359(6371):97-103, 2018. e-Pub 2018. PMID: 29097493.
41. Chao AW, Bhati M, DuPont HL, Nataro J, Carlin L, Okhuysen P. Clinical Features and Molecular Epidemiology of Diarrheagenic Escherichia coli Pathotypes Identified by Fecal Gastrointestinal Multiplex Nucleic Acid Amplification in Patients with Cancer and Diarrhea. Diagn Microbiol Infect Dis 89:235-240, 2017. e-Pub 2017. PMID: 28931467.
42. Ghosh, N, Malik, FA, Daver, RG, Vanichanan, J, Okhuysen, PC. Viral associated diarrhea in immunocompromised and cancer patients at a large comprehensive cancer center. Infectious Diseases 49(2):113-119, 2017. e-Pub 2017. PMID: 27620005.
43. Chappell, CL, Darkoh, C, Shimmin, L, Farhana, N, Kim, DK, Okhuysen, PC, Hixson, Je. Fecal indole as a biomarker of susceptibility to cryptosporidium infection. Infection and Immunity 84(8):2299-2306, 2016. e-Pub 2016. PMID: 27245413.
44. Mocroft A, Lundgren JD, Ross M, Law M, Reiss P, Kirk O, Smith C, Wentworth D, Neuhaus J, Fux CA, Moranne O, Morlat P, Johnson MA, Ryom L, group DS. Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study. PLoS Med 12(3):e1001809, 2015. e-Pub 2015. PMID: 25826420.
45. Chappell, CL, Okhuysen, PC, Langer-Curry, RC, Lupo, PJ, Widmer, G, Tzipori, S. Cryptosporidium muris: Infectivity and illness in healthy adult volunteers. American Journal of Tropical Medicine and Hygiene 92(1):50-55, 2015. e-Pub 2015. PMID: 25311695.
46. Darkoh C, Chappell C, Gonzales C, Okhuysen P. A Rapid and Specific Method for the Detection of Indole in Complex Biological Samples. Appl Environ Microbiol 81(23):8093-8097, 2015. e-Pub 2015. PMID: 26386049.
47. Murray DD, Suzuki K, Law M, Trebicka J, Neuhaus J, Wentworth D, Johnson M, Vjecha MJ, Kelleher AD, Emery S. Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study. PLoS One 10(10):e0139981, 2015. e-Pub 2015. PMID: 26465293.
48. Mahale, P, Okhuysen, PC, Torres, HA. Does Chemotherapy Cause Viral Relapse in Cancer Patients With Hepatitis C Infection Successfully Treated With Antivirals?. Clinical Gastroenterology and Hepatology 12(6):1051-1054.e1, 2014. e-Pub 2014. PMID: 24211293.
49. Nordell AD, McKenna M, ÁH B, Duprez D, Neuhaus J, Neaton JD, SMART I, Groups ES, Committee SS. Severity of cardiovascular disease outcomes among patients with HIV is related to markers of inflammation and coagulation. J Am Heart Assoc 3(3), 2014. e-Pub 2014. PMID: 24870935.
50. Borges AH, O'Connor JL, Phillips AN, Baker JV, Vjecha MJ, Losso MH, Klinker H, Lopardo G, Williams I, Lundgren JD, Study Group IS, Group ES, Committee SS. Factors associated with D-dimer levels in HIV-infected individuals. PLoS One 9(3), 2014. e-Pub 2014. PMID: 24626096.
51. Ajami NJ, Kavanagh OV, Ramani S, Crawford SE, Atmar RL, Jiang ZD, Okhuysen PC, Estes MK, DuPont HL. Seroepidemiology of norovirus-associated travelers' diarrhea. J Travel Med 21(1):6-11, 2014. e-Pub 2014. PMID: 24383649.
52. Nair P, Okhuysen PC, Jiang ZD, Carlin LG, Belkind-Gerson J, Flores J, Paredes M, DuPont HL. Persistent abdominal symptoms in US adults after short-term stay in Mexico. J Travel Med 21(3):153-8, 2014. e-Pub 2014. PMID: 24621006.
53. McGrath DM, Barbu EM, Driessen WH, Lasco TM, Tarrand JJ, Okhuysen PC, Kontoyiannis DP, Sidman RL, Pasqualini R, Arap W. Mechanism of action and initial evaluation of a membrane active all-D-enantiomer antimicrobial peptidomimetic. Proc Natl Acad Sci U S A 110(9):3477-82, 2013. e-Pub 2013. PMID: 23345420.
54. Bjerk SM, Baker JV, Emery S, Neuhaus J, Angus B, Gordin FM, Pett SL, Stephan C, Kunisaki KM, Study Group IS. Biomarkers and bacterial pneumonia risk in patients with treated HIV infection: a case-control study. PLoS One 8(2):e56249, 2013. e-Pub 2013. PMID: 23457535.
55. Leder K, Torresi J, Libman MD, Cramer JP, Castelli F, Schlagenhauf P, Wilder-Smith A, Wilson ME, Keystone JE, Schwartz E, Barnett ED, von Sonnenburg F, Brownstein JS, Cheng AC, Sotir MJ, Esposito DH, Freedman, DO. GeoSentinel Surveillance of Illness in Returned Travelers, 2007-2011. Ann Intern Med 158(6):456-468, 2013. e-Pub 2013. PMID: 23552375.
56. Matteelli A, Schlagenhauf P, Carvalho AC, Weld L, Davis XM, Wilder-Smith A, Barnett ED, Parola P, Pandey P, Han P, Castelli F, Network GS. Travel-associated sexually transmitted infections: an observational cross-sectional study of the GeoSentinel surveillance database. Lancet Infect Dis(13):205-213, 2013. e-Pub 2013. PMID: 23182931.
57. Gautret P, Gaudart J, Leder K, Schwartz E, Castelli F, Lim PL, Murphy H, Keystone J, Cramer J, Shaw M, Boddaert J, von Sonnenburg F, Parola P, Network GS. Travel-associated illness in older adults (>60 y). J Travel Med 19(3):169-177, 2012. e-Pub 2012. PMID: 22530824.
58. Flores-Figueroa J, Okhuysen PC, von Sonnenburg F, DuPont HL, Libman MD, Keystone JS, Hale DC, Burchard G, Han PV, Wilder-Smith A, Freedman DO, Network GS. Patterns of illness in travelers visiting Mexico and Central America: the GeoSentinel experience. Clin Infect Dis 53(6):523-31, 2011. e-Pub 2011. PMID: 21832261.
59. Flores J, Dupont HL, Jiang ZD, Okhuysen PC, Melendez-Romero JH, Gonzalez-Estrada A, Carrillo I, Paredes M. A randomized, double-blind, pilot study of rifaximin 550 mg versus placebo in the prevention of travelers' diarrhea in Mexico during the dry season. J Travel Med 18(5):333-6, 2011. e-Pub 2011. PMID: 21896097.
60. Chappell CL, Okhuysen PC, Langer-Curry RC, Akiyoshi DE, Widmer G, Tzipori S. Cryptosporidium meleagridis: infectivity in healthy adult volunteers. Am J Trop Med Hyg 85(2):238-42, 2011. e-Pub 2011. PMID: 21813841.
61. Cozzi-Lepri A, French MA, Baxter J, Okhuysen P, Plana M, Neuhaus J, Landay A, study group IS. Resumption of HIV replication is associated with monocyte/macrophage derived cytokine and chemokine changes: results from a large international clinical trial. AIDS 25(9):1207-17, 2011. e-Pub 2011. PMID: 21505304.
62. Mohamed JA, DuPont HL, Flores J, Palur H, Nair P, Jiang ZD, Guo D, Belkind-Gerson J, Okhuysen PC. Single nucleotide polymorphisms in the promoter of the gene encoding the lipopolysaccharide receptor CD14 are associated with bacterial diarrhea in US and Canadian travelers to Mexico. Clin Infect Dis 52(11):1332-41, 2011. e-Pub 2011. PMID: 21596674.
63. Paredes-Paredes M, Okhuysen PC, Flores J, Mohamed JA, Padda RS, Gonzalez-Estrada A, Haley CA, Carlin LG, Nair P, DuPont HL. Seasonality of diarrheagenic Escherichia coli pathotypes in the US students acquiring diarrhea in Mexico. J Travel Med 18(2):121-5, 2011. e-Pub 2011. PMID: 21366796.
64. Villa NA, Okhuysen PC, Flores-Figueroa J, Jiang ZD, Belkind-Gerson J, Paredes M, Mohamed JA, Nair P, Carlin L, DuPont HL. Campylobacter jejuni is not an important pathogen as a cause of diarrhea in US travelers to Mexico. J Travel Med 18(1):56-8, 2011. e-Pub 2011. PMID: 21199144.
65. Ouyang-Latimer J, Ajami NJ, Jiang ZD, Okhuysen PC, Paredes M, Flores J, Dupont HL. Biochemical and genetic diversity of enterotoxigenic Escherichia coli associated with diarrhea in United States students in Cuernavaca and Guadalajara, Mexico, 2004-2007. J Infect Dis 201(12):1831-8, 2010. e-Pub 2010. PMID: 20443738.
66. Koo HL, Ajami NJ, Jiang ZD, Neill FH, Atmar RL, Ericsson CD, Okhuysen PC, Taylor DN, Bourgeois AL, Steffen R, DuPont HL. Noroviruses as a cause of diarrhea in travelers to Guatemala, India, and Mexico. J Clin Microbiol 48(5):1673-6, 2010. e-Pub 2010. PMID: 20305012.
67. Flores J, DuPont HL, Paredes-Paredes M, Aguirre-Garcia MM, Rojas A, Gonzalez A, Okhuysen PC. Pilot study of whole-blood gamma interferon response to the Vibrio cholerae toxin B subunit and resistance to enterotoxigenic Escherichia coli-associated diarrhea. Clin Vaccine Immunol 17(5):879-81, 2010. e-Pub 2010. PMID: 20219880.
68. Martinez-Sandoval F, Ericsson CD, Jiang ZD, Okhuysen PC, Romero JH, Hernandez N, Forbes WP, Shaw A, Bortey E, DuPont HL. Prevention of travelers' diarrhea with rifaximin in US travelers to Mexico. J Travel Med 17(2):111-7, 2010. e-Pub 2010. PMID: 20412178.
69. INSIGHT-SMART Study Group Martinez E, Visnegarwala F, Grund B, Thomas A, Gibert C, Shlay J, Drummond F, Pearce D, Edwards S, Reiss P, El-Sadr W, Carr A. The effects of intermittent, CD4-guided antiretroviral therapy on body composition and metabolic parameters. AIDS 24(3):353-363, 2010. e-Pub 2010. PMID: 20057309.
70. Ajami N, Koo H, Darkoh C, Atmar RL, Okhuysen PC, Jiang ZD, Flores J, Dupont HL. Characterization of norovirus-associated traveler's diarrhea. Clin Infect Dis 51(2):123-130, 2010. e-Pub 2010. PMID: 20540620.
71. INSIGHT-ESPRIT Study Group Abrams D, Levy Y, Losso MH, Babiker A, Collins G, Cooper DA, Darbyshire J, Emery S, Fox L, Gordin F, Lane HC, Lundgren JD, Mitsuyasu R, Neaton JD, Phillips A, Routy JP, Tambussi G, Wentworth D. Interleukin-2 therapy in patients with HIV infection. N Engl J Med 361(16):1548-1559, 2009. e-Pub 2009. PMID: 19828532.
72. INSIGHT-SMART Study Group Rodger AJ, Fox Z, Lundgren JD, Kuller LH, Boesecke C, Gey D, Skoutelis A, Goetz MB, Phillips AN. Activation and coagulation biomarkers are independent predictors of the development of opportunistic disease in patients with HIV infection. J Infect Dis 200(6):973-983, 2009. e-Pub 2009. PMID: 19678756.
73. INSIGHT-SMART Study Group Grund B, Peng G, Gibert CL, Hoy JF, Isaksson RL, Shlay JC, Martinez E, Reiss P, Visnegarwala F, Carr AD. Continuous antiretroviral therapy decreases bone mineral density. AIDS 23(12):1519-1529, 2009. e-Pub 2009. PMID: 19531929.
74. Mohamed JA, DuPont HL, Jiang ZD, Flores J, Carlin LG, Belkind-Gerson J, Martinez-Sandoval FG, Guo D, White AC, Okhuysen PC. A single-nucleotide polymorphism in the gene encoding osteoprotegerin, an anti-inflammatory protein produced in response to infection with diarrheagenic Escherichia coli, is associated with an increased risk of nonsecretory bacterial diarrhea in North American travelers to Mexico. J Infect Dis 199(4):477-85, 2009. e-Pub 2009. PMID: 19128145.
75. INSIGHT-SMART Study Group Mocroft A, Wyatt C, Szczech L, Neuhaus J, El-Sadr W, Tracy R, Kuller L, Shlipak M, Angus B, Klinker H, Ross M. Interruption of antiretroviral therapy is associated with increased plasma cystatin C. AIDS 23(1):71-82, 2009. e-Pub 2009. PMID: 2761385.
76. Fox Z, Phillips A, Cohen C, Neuhaus J, Baxter J, Emery S, Hirschel B, Hullsiek KH, Stephan C, Lundgren J, SMART study Group. Viral resuppression and detection of drug resistance following interruption of a suppressive non-nucleoside reverse transcriptase inhibitor-based regimen. AIDS 22(17):2279-89, 2008. e-Pub 2008. PMID: 18981767.
77. El-Sadr, W, Grund, B, Neaton, J, Neuhaus, J, Cohen, C, Darbyshire, JH, Babiker, A, Emery, S, Lundgren, JD, Phillips, A, Jensen, KB, Gey, D, Borup, L, Pearson, M, Jansson, PO, Jensen, BG, Tverland, J, Juncker-Benzon, H, Fox, Z, Phillips, AN, Babiker, AG, Palfreeman, A, Fleck, SL, Dodds, W, King, E, Cordwell, B, Van Hooff, F, Collaco-Moraes, Y, Angus, B, Cooper, DA, Drummond, F, Connor, SA, Satchell, CS, Gunn, S, Oka, S, Delfino, MA, Merlin, K, McGinley, C, Gordin, F, Finley, E, Dietz, D, Chesson, C, Vjecha, MJ, Standridge, B, Bartsch, G, DuChene, A, George, M, Harrison, M, Krum, E, Okhuysen, PC. Risk for opportunistic disease and death after reinitiating continuous antiretroviral therapy in patients with HIV previously receiving episodic therapy. Annals of internal medicine 149(5):289-299, 2008. e-Pub 2008. PMID: 18765698.
78. Nallapareddy SR, Singh KV, Okhuysen PC, Murray BE. A functional collagen adhesin gene, acm, in clinical isolates of Enterococcus faecium correlates with the recent success of this emerging nosocomial pathogen. Infect Immun 76(9):4110-9, 2008. e-Pub 2008. PMID: 18591238.
79. Nair P, Mohamed JA, DuPont HL, Figueroa JF, Carlin LG, Jiang ZD, Belkind-Gerson J, Martinez-Sandoval FG, Okhuysen PC. Epidemiology of cryptosporidiosis in North American travelers to Mexico. Am J Trop Med Hyg 79(2):210-4, 2008. e-Pub 2008. PMID: 18689626.
80. Flores J, DuPont HL, Lee SA, Belkind-Gerson J, Paredes M, Mohamed JA, Armitige LY, Guo DC, Okhuysen PC. Influence of host interleukin-10 polymorphisms on development of traveler's diarrhea due to heat-labile enterotoxin-producing Escherichia coli in travelers from the United States who are visiting Mexico. Clin Vaccine Immunol 15(8):1194-8, 2008. e-Pub 2008. PMID: 18579697.
81. Grimes KA, Mohamed JA, Dupont HL, Padda RS, Jiang ZD, Flores J, Belkind-Gerson J, Martinez-Sandoval FG, Okhuysen PC. PCR-based assay using occult blood detection cards for detection of diarrheagenic Escherichia coli in specimens from U.S. travelers to Mexico with acute diarrhea. J Clin Microbiol 46(7):2227-30, 2008. e-Pub 2008. PMID: 18480224.
82. Frech SA, Dupont HL, Bourgeois AL, McKenzie R, Belkind-Gerson J, Figueroa JF, Okhuysen PC, Guerrero NH, Martinez-Sandoval FG, Meléndez-Romero JH, Jiang ZD, Asturias EJ, Halpern J, Torres OR, Hoffman AS, Villar CP, Kassem RN, Flyer DC, Andersen BH, Kazempour K, Breisch SA, Glenn GM. Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial. Lancet 371(9629):2019-25, 2008. e-Pub 2008. PMID: 18554712.
83. Lupo PJ, Langer-Curry RC, Robinson M, Okhuysen PC, Chappell CL. Cryptosporidium muris in a Texas canine population. Am J Trop Med Hyg 78(6):917-21, 2008. e-Pub 2008. PMID: 18541769.
84. Flores J, DuPont HL, Jiang ZD, Belkind-Gerson J, Mohamed JA, Carlin LG, Padda RS, Paredes M, Martinez-Sandoval JF, Villa NA, Okhuysen PC. Enterotoxigenic Escherichia coli heat-labile toxin seroconversion in US travelers to Mexico. J Travel Med 15(3):156-61, 2008. e-Pub 2008. PMID: 18494692.
85. Emery, S, Neuhaus, J, Phillips, A, Babiker, A, Cohen, C, Gatell, J, Girard, PM, Grund, B, Law, MG, Losso, M, Palfreeman, A, Wood, R, Gordin, F, Finley, E, Dietz, D, Chesson, C, Vjecha, MJ, Standridge, B, Schmetter, B, Grue, L, Willoughby, M, Demers, A, Lundgren, JD, Phillips, A, Dragsted, UB, Jensen, KB, Fau, A, Borup, L, Pearson, M, Jansson, PO, Jensen, BG, Benfield, TL, Darbyshire, JH, Babiker, AG, Palfreeman, A, Fleck, SL, Collaco-Moraes, Y, Cordwell, B, Dodds, W, Van Hooff, F, Wyzydrag, L, Cooper, DA, Drummond, F, Connor, SA, Satchell, CS, Gunn, S, Oka, S, Delfino, MA, Merlin, K, Okhuysen, PC. Major clinical outcomes in antiretroviral therapy (ART)-naive participants and in those not receiving ART at baseline in the SMART Study. Journal of Infectious Diseases 197(8):1133-1144, 2008. e-Pub 2008. PMID: 18476292.
86. Lundgren, JD, Babiker, A, El-Sadr, W, Emery, S, Grund, B, Neaton, J, Neuhaus, J, Phillips, A, Gordin, F, Finley, E, Dietz, D, Chesson, C, Vjecha, MJ, Standridge, B, Schmetter, B, Grue, L, Willoughby, M, Demers, A, Phillips, A, Dragsted, UB, Jensen, KB, Fau, A, Borup, L, Pearson, M, Jansson, PO, Jensen, BG, Benfield, TL, Darbyshire, JH, Babiker, AG, Palfreeman, A, Fleck, SL, Collaco-Moraes, Y, Cordwell, B, Dodds, W, van Hoff, F, Wazydrag, L, Cooper, DA, Drummond, F, Connor, SA, Satchell, CS, Gunn, S, Oka, S, Delfino, MA, Merlin, K, McGinley, C, DuChene, A, Harrison, M, George, M, Hogan, C, Okhuysen, PC. Inferior clinical outcome of the CD4+ cell count-guided antiretroviral treatment interruption strategy in the SMART study. Journal of Infectious Diseases 197(8):1145-1155, 2008. e-Pub 2008. PMID: 18476293.
87. Huang DB, Brown EL, DuPont HL, Cerf J, Carlin L, Flores J, Belkind-Gerson J, Nataro JP, Okhuysen PC. Seroprevalence of the enteroaggregative Escherichia coli virulence factor dispersin among USA travellers to Cuernavaca, Mexico: a pilot study. J Med Microbiol 57(Pt 4):476-9, 2008. e-Pub 2008. PMID: 18349368.
88. Carr A, Grund B, Neuhaus J, El-Sadr WM, Grandits G, Gibert C, Prineas RJ, Investigators SS. Asymptomatic myocardial ischaemia in HIV-infected adults. AIDS(22):257-267, 2008. e-Pub 2008. PMID: 18097228.
89. Planque S, Mitsuda Y, Taguchi H, Salas M, Morris MK, Nishiyama Y, Kyle R, Okhuysen P, Escobar M, Hunter R, Sheppard HW, Hanson C, Paul S. Characterization of gp120 hydrolysis by IgA antibodies from humans without HIV infection. AIDS Res Hum Retroviruses 23(12):1541-54, 2007. e-Pub 2007. PMID: 18160012.
90. Huang DB, Mohamed JA, Nataro JP, DuPont HL, Jiang ZD, Okhuysen PC. Virulence characteristics and the molecular epidemiology of enteroaggregative Escherichia coli isolates from travellers to developing countries. J Med Microbiol 56(Pt 10):1386-92, 2007. e-Pub 2007. PMID: 17893178.
91. Ericsson CD, DuPont HL, Okhuysen PC, Jiang ZD, DuPont MW. Loperamide plus azithromycin more effectively treats travelers' diarrhea in Mexico than azithromycin alone. J Travel Med 14(5):312-9, 2007. e-Pub 2007. PMID: 17883462.
92. Jiang ZD, Garey KW, Price M, Graham G, Okhuysen P, Dao-Tran T, LaRocco M, DuPont HL. Association of interleukin-8 polymorphism and immunoglobulin G anti-toxin A in patients with Clostridium difficile-associated diarrhea. Clin Gastroenterol Hepatol 5(8):964-8, 2007. e-Pub 2007. PMID: 17618838.
93. Aguirre-García MM, Okhuysen PC. Cryptosporidium parvum: identification and characterization of an acid phosphatase. Parasitol Res 101(1):85-9, 2007. e-Pub 2007. PMID: 17252269.
94. Okhuysen, PC. Travelers' diarrhea, new insights. Journal of Clinical Gastroenterology 41(SUPPL. 1):S20-S23, 2007. e-Pub 2007.
95. Mohamed JA, DuPont HL, Jiang ZD, Belkind-Gerson J, Figueroa JF, Armitige LY, Tsai A, Nair P, Martinez-Sandoval FJ, Guo DC, Hayes P, Okhuysen PC. A novel single-nucleotide polymorphism in the lactoferrin gene is associated with susceptibility to diarrhea in North American travelers to Mexico. Clin Infect Dis 44(7):945-52, 2007. e-Pub 2007. PMID: 17342646.
96. Dupont HL, Jiang ZD, Belkind-Gerson J, Okhuysen PC, Ericsson CD, Ke S, Huang DB, Dupont MW, Adachi JA, De La Cabada FJ, Taylor DN, Jaini S, Martinez Sandoval F. Treatment of travelers' diarrhea: randomized trial comparing rifaximin, rifaximin plus loperamide, and loperamide alone. Clin Gastroenterol Hepatol 5(4):451-6, 2007. e-Pub 2007. PMID: 17382603.
97. DuPont HL, Haake R, Taylor DN, Ericsson CD, Jiang ZD, Okhuysen PC, Steffen R. Rifaximin treatment of pathogen-negative travelers' diarrhea. J Travel Med 14(1):16-9, 2007. e-Pub 2007. PMID: 17241249.
98. Wang HC, Dann SM, Okhuysen PC, Lewis DE, Chappell CL, Adler DG, White AC. High levels of CXCL10 are produced by intestinal epithelial cells in AIDS patients with active cryptosporidiosis but not after reconstitution of immunity. Infect Immun 75(1):481-7, 2007. e-Pub 2007. PMID: 17043107.
99. Mohamed JA, Huang DB, Jiang ZD, DuPont HL, Nataro JP, Belkind-Gerson J, Okhuysen PC. Association of putative enteroaggregative Escherichia coli virulence genes and biofilm production in isolates from travelers to developing countries. J Clin Microbiol 45(1):121-6, 2007. e-Pub 2007. PMID: 17093030.
100. Research Group TE. Predictors of CD4 count change over 8 months of follow up in HIV-1-infected patients with a CD4 count>/=300 cells/muL who were assigned to 7.5 MIU interleukin-2. HIV Med(8):112-123, 2007. e-Pub 2007. PMID: 17352768.
101. El-Sadr WM, Lundgren J, Neaton JD, Gordin F, Abrams D, Arduino RC, Babiker A, Burman W, Clumeck N, Cohen CJ, Cohn D, Cooper D, Darbyshire J, Emery S, Fatkenheuer G, Gazzard B, Grund B, Hoy J, Klingman K, Losso M, Markowitz N, Neuhaus J, Phillips A, Rappoport C. CD4+ count-guided interruption of antiretroviral treatment. N Engl J Med 355(22):2283-96, 2006. e-Pub 2006. PMID: 17135583.
102. Chappell CL, Okhuysen PC, Langer-Curry R, Widmer G, Akiyoshi DE, Tanriverdi S, Tzipori S. Cryptosporidium hominis: experimental challenge of healthy adults. Am J Trop Med Hyg 75(5):851-7, 2006. e-Pub 2006. PMID: 17123976.
103. Huang DB, Nataro JP, DuPont HL, Kamat PP, Mhatre AD, Okhuysen PC, Chiang T. Enteroaggregative Escherichia coli is a cause of acute diarrheal illness: a meta-analysis. Clin Infect Dis 43(5):556-63, 2006. e-Pub 2006. PMID: 16886146.
104. Ko G, Jiang ZD, Okhuysen PC, DuPont HL. Fecal cytokines and markers of intestinal inflammation in international travelers with diarrhea due to Noroviruses. J Med Virol 78(6):825-8, 2006. e-Pub 2006. PMID: 16628572.
105. Jiang ZD, DuPont HL, Garey K, Price M, Graham G, Okhuysen P, Dao-Tran T, LaRocco M. A common polymorphism in the interleukin 8 gene promoter is associated with Clostridium difficile diarrhea. Am J Gastroenterol 101(5):1112-6, 2006. e-Pub 2006. PMID: 16573784.
106. DuPont HL, Jiang ZD, Okhuysen PC, Ericsson CD, de la Cabada FJ, Ke S, DuPont MW, Martinez-Sandoval F. Antibacterial chemoprophylaxis in the prevention of traveler's diarrhea: evaluation of poorly absorbed oral rifaximin. Clin Infect Dis 41 Suppl 8(SUPPL. 11):S571-6, 2005. e-Pub 2005. PMID: 16267721.
107. Ko G, Garcia C, Jiang ZD, Okhuysen PC, Belkind-Gerson J, Glass RI, DuPont HL. Noroviruses as a cause of traveler's diarrhea among students from the United States visiting Mexico. J Clin Microbiol 43(12):6126-9, 2005. e-Pub 2005. PMID: 16333110.
108. Mohr JF, McKinnon PS, Peymann PJ, Kenton I, Septimus E, Okhuysen PC. A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone. Pharmacotherapy 25(10):1303-9, 2005. e-Pub 2005. PMID: 16185173.
109. Okhuysen PC, Chappell CL, Lewis DE, Robinson P, White AC. Treatment of chronic cryptosporidiosis in AIDS with rIL-12 induces an immune response associated with improvement but severe side-effects. AIDS 19(12):1333-4, 2005. e-Pub 2005. PMID: 16052094.
110. DuPont HL, Jiang ZD, Okhuysen PC, Ericsson CD, de la Cabada FJ, Ke S, DuPont MW, Martinez-Sandoval F. A randomized, double-blind, placebo-controlled trial of rifaximin to prevent travelers' diarrhea. Ann Intern Med 142(10):805-12, 2005. e-Pub 2005. PMID: 15897530.
111. Okhuysen, PC, DuPont, HL. Post-diarrhea chronic intestinal symptoms and irritable bowel syndrome in North American travelers to Mexico. American Journal of Gastroenterology 100(3):729-730, 2005. e-Pub 2005. PMID: 15330917.
112. Kjos SA, Jenkins M, Okhuysen PC, Chappell CL. Evaluation of recombinant oocyst protein CP41 for detection of cryptosporidium-specific antibodies. Clin Diagn Lab Immunol 12(2):268-72, 2005. e-Pub 2005. PMID: 15699421.
113. Roberts JC, Singh KV, Okhuysen PC, Murray BE. Molecular epidemiology of the fsr locus and of gelatinase production among different subsets of Enterococcus faecalis isolates. J Clin Microbiol 42(5):2317-2320, 2004. e-Pub 2004. PMID: 15131223.
114. Huang DB, DuPont HL, Jiang ZD, Carlin L, Okhuysen PC. Interleukin-8 response in an intestinal HCT-8 cell line infected with enteroaggregative and enterotoxigenic Escherichia coli. Clin Diagn Lab Immunol 11(3):548-551, 2004. e-Pub 2004. PMID: 15138180.
115. Okhuysen PC, Rogers GA, Crisanti A, Spano F, Huang DB, Chappell CL, Tzipori S. Antibody response of healthy adults to recombinant thrombospondin-related adhesive protein of cryptosporidium 1 after experimental exposure to cryptosporidium oocysts. Clin Diagn Lab Immunol 11(2):235-238, 2004. e-Pub 2004. PMID: 15013968.
116. White AC, Robinson P, Okhuysen PC. Human studies provide insight into the pathogenesis, immunology, and treatment of cryptosporidiosis. Clin Infect Dis 37(7):989; author reply 989-90, 2003. e-Pub 2003. PMID: 13130414.
117. Jiang ZD, Okhuysen PC, Guo DC, He R, King TM, DuPont HL, Milewicz DM. Genetic susceptibility to enteroaggregative Escherichia coli diarrhea: polymorphism in the interleukin-8 promotor region. J Infect Dis 188(4):506-511, 2003. e-Pub 2003. PMID: 12898436.
118. Robinson P, Okhuysen PC, Chappell CL, Weinstock JV, Lewis DE, Actor JK, White AC. Substance P expression correlates with severity of diarrhea in cryptosporidiosis. J Infect Dis 188(2):290-6, 2003. e-Pub 2003. PMID: 12854086.
119. Alcantara CS, Yang CH, Steiner TS, Barrett LJ, Lima AA, Chappell CL, Okhuysen PC, White AC, Guerrant RL. Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis. Am J Trop Med Hyg 68(3):325-8, 2003. e-Pub 2003. PMID: 12685639.
120. Millership JJ, Chappell C, Okhuysen PC, Snowden KF. Characterization of aminopeptidase activity from three species of microsporidia: Encephalitozoon cuniculi, Encephalitozoon hellem, and Vittaforma corneae. J Parasitol 88(5):843-848, 2002. e-Pub 2002. PMID: 12435118.
121. Graham, DR, Lucasti, C, Malafaia, O, Nichols, RL, Holtom, P, Perez, NQ, McAdams, A, Woods, GL, Ceesay, TP, Gesser, R, Bauwens, EJ, Ekengren, F, Eng, R, Gainer, RB, Garreaud, C, Geckler, R, Gelfand, M, Gezon, J, Graham, DR, Hanna, C, Jasovich, A, Klein, SR, Kurtz, T, Lema, J, Livingston, D, Lopardo, G, Lucasti, C, Lucia, A, Mader, JT, Malafaia, O, Mangiante, E, Marcano, H, Miskin, B, Nahass, R, Nichols, RL, Okhuysen, PC, Parish, LC, Patzakis, M, Perez, NQ, Poole, J, Postier, RG, Salomone, J, Schwartz, R, Standiford, H, Tan, J, Tice, A, Wilson, SE, Wittmann, D. Ertapenem once daily versus piperacillin-tazobactam 4 times per day for treatment of complicated skin and skin-structure infections in adults. Clinical Infectious Diseases 34(11):1460-1468, 2002. e-Pub 2002. PMID: 12015692.
122. Padda RS, Tsai A, Chappell CL, Okhuysen PC. Molecular cloning and analysis of the Cryptosporidium parvum aminopeptidase N gene. Int J Parasitol 32(2):187-97, 2002. e-Pub 2002. PMID: 11812496.
123. Teunis PF, Chappell CL, Okhuysen PC. Cryptosporidium dose-response studies: variation between hosts. Risk Anal 22(3):475-485, 2002. e-Pub 2002. PMID: 12088227.
124. Okhuysen PC, Rich SM, Chappell CL, Grimes KA, Widmer G, Feng X, Tzipori S. Infectivity of a Cryptosporidium parvum isolate of cervine origin for healthy adults and interferon-gamma knockout mice. J Infect Dis 185(9):1320-1325, 2002. e-Pub 2002. PMID: 12001050.
125. Teunis PF, Chappell CL, Okhuysen PC. Cryptosporidium dose response studies: variation between isolates. Risk Anal 22(1):175-183, 2002. e-Pub 2002. PMID: 12017359.
126. Millership JJ, Chappell CL, Okhuysen PC, Snowden KF. Characterization of a cytosolic aminopeptidase from Encephalitozoon intestinalis. Parasitology 124(124 Pt 1):1-7, 2002. e-Pub 2002. PMID: 11811798.
127. Robinson, P, Okhuysen, PC, Chappell, CL, Lewis, DE, Shahab, I, Lahoti, S, White, AC. Expression of IL-15 and IL-4 in IFN-γ-independent control of experimental human Cryptosporidium parvum infection. Cytokine 15(1):39-46, 2001. e-Pub 2001. PMID: 11509007.
128. Okhuysen, PC, Robinson, P, Nguyen, MT, Nannini, EC, Lewis, DE, Janecki, A, Chappell, CL, White, AC. Jejunal cytokine response in AIDS patients with chronic cryptosporidiosis and during immune reconstitution. AIDS 15(6):802-804, 2001. e-Pub 2001. PMID: 11371698.
129. Messner, MJ, Chappell, CL, Okhuysen, PC. Risk assessment for Cryptosporidium. A hierarchical Bayesian analysis of human dose response data. Water Research 35(16):3934-3940, 2001. e-Pub 2001. PMID: 12230176.
130. Robinson, P, Okhuysen, PC, Chappell, CL, Lewis, DE, Shahab, I, Janecki, A, White, AC. Expression of tumor necrosis factor alpha and interleukin 1β in jejuna of volunteers after experimental challenge with Cryptosporidium parvum correlates with exposure but not with symptoms. Infection and Immunity 69(2):1172-1174, 2001. e-Pub 2001. PMID: 11160015.
131. Millership, JJ, Didier, ES, Okhuysen, PC, Maddry, JA, Kwong, CD, Chen, X, Snowden, KF. In vitro and in vivo evaluation of aminopeptidase inhibitors as antimicrosporidial therapies. Journal of Eukaryotic Microbiology 48(SUPPL):95S-98S, 2001. e-Pub 2001. PMID: 11906096.
132. Robinson, P, Okhuysen, PC, Chappell, CL, Lewis, DE, Shahab, I, Lahoti, S, White, AC. Transforming growth factor β1 is expressed in the jejunum after experimental Cryptosporidium parvum infection in humans. Infection and Immunity 68(9):5405-5407, 2000. e-Pub 2000. PMID: 10948171.
133. White, AC, Robinson, P, Okhuysen, PC, Lewis, DE, Shahab, I, Lahoti, S, DuPont, HL, Chappell, CL. Interferon-γ expression in jejunal biopsies in experimental human cryptosporidiosis correlates with prior sensitization and control of oocyst excretion. Journal of Infectious Diseases 181(2):701-709, 2000. e-Pub 2000. PMID: 10669358.
134. Dann, SM, Okhuysen, PC, Salameh, BM, DuPont, HL, Chappell, CL. Fecal antibodies to Cryptosporidium parvum in healthy volunteers. Infection and Immunity 68(9):5068-5074, 2000. e-Pub 2000. PMID: 10948127.
135. Chappell, CL, Okhuysen, PC, Sterling, CR, Wang, C, Jakubowski, W, DuPont, HL. Infectivity of Cryptosporidium parvum in healthy adults with pre- existing anti-C. parvum serum immunoglobulin G. American Journal of Tropical Medicine and Hygiene 60(1):157-164, 1999. e-Pub 1999. PMID: 9988341.
136. Okhuysen PC, Chappell CL, Crabb JH, Sterling CR, DuPont HL. Virulence of Three Distinct Cryptosporidium parvum Isolates for Healthy Adults. J Infect Dis 180(180):1275-1281, 1999. e-Pub 1999. PMID: 10479158.
137. Okhuysen, PC, Chappell, CL, Sterling, CR, Jakubowski, W, DuPont, HL. Susceptibility and serologic response of healthy adults to reinfection with Cryptosporidium parvum. Infection and Immunity 66(2):441-443, 1998. e-Pub 1998. PMID: 9453592.
138. Okhuysen, PC, Chappell, CL, Crabb, JH, Valdez, LM, Douglass, ET, DuPont, HL. Prophylactic effect of bovine anti-Cryptosporidium hyperimmune colostrum immunoglobulin healthy volunteers challenged with Cryptosporidium parvum. Clinical Infectious Diseases 26(6):1324-1329, 1998. e-Pub 1998. PMID: 9636857.
139. Moss, DM, Chappell, CL, Okhuysen, PC, DuPont, HL, Arrowood, MJ, Hightower, AW, Lammie, PJ. The antibody response to 27-, 17-, and 15-kDa Cryptosporidium antigens following experimental infection in humans. Journal of Infectious Diseases 178(3):827-833, 1998. e-Pub 1998. PMID: 9728553.
140. Valdez, LM, Dang, H, Okhuysen, PC, Chappell, CL. Flow cytometric detection of Cryptosporidium oocysts in human stool samples. Journal of Clinical Microbiology 35(8):2013-2017, 1997. e-Pub 1997. PMID: 9230372.
141. Okhuysen, PC. Onchocerciasis in an expatriate living in Cameroon. Journal of Travel Medicine 4(1):11-13, 1997. e-Pub 1997. PMID: 9815471.
142. Valdez, LM, Schwab, P, Okhuysen, PC, Rakita, RM. Paradoxical subcutaneous tuberculous abscess. Clinical Infectious Diseases 24(4):734, 1997. e-Pub 1997. PMID: 9145751.
143. Okhuysen, PC, Chappell, CL, Kettner, C, Sterling, CR. Cryptosporidium parvum metalloaminopeptidase inhibitors prevent in vitro excystation. Antimicrobial agents and chemotherapy 40(12):2781-2784, 1996. e-Pub 1996. PMID: 9124840.
144. White, AC, Robinson, P, Okhuysen, PC, Steephen, A, Lewis, DE, Atmar, RL, DuPont, HL, Chappell, CL. Intestinal tnfa in cryptosporidiosis. Journal of Investigative Medicine 44(3):218a, 1996. e-Pub 1996.
145. Chappell, CL, Okhuysen, PC, Sterling, CR, DuPont, HL. Cryptosporidium parvum: intensity of infection and oocyst excretion patterns in healthy volunteers. Journal of Infectious Diseases 173(1):232-236, 1996. e-Pub 1996. PMID: 8537664.
146. Coque TM, Tomayko JF, Ricke SC, Okhuysen PC, Murray BE. Vancomycin Resistant Enterococci from Nosocomial, Community and Animal Sources in the Unites States. Antimicrobial Agents and Chemotherapy(40):2605-2609, 1996. e-Pub 1996. PMID: 8913473.
147. Okhuysen, PC, DuPont, HL, Ericsson, CD, Marani, SK, Martinez-Sandoval, FG, Olesen, MA, Ravelli, GP. Zaldaride maleate (a new calmodulin antagonist) versus loperamide in the treatment of traveler’s diarrhea. Clinical Infectious Diseases 21(2):341-344, 1995. e-Pub 1995. PMID: 8562742.
148. DuPont, HL, Chappell, CL, Sterling, CR, Okhuysen, PC, Rose, JB, Jakubowski, W. The infectivity of cryptosporidium parvum in healthy volunteers. New England Journal of Medicine 332(13):855-859, 1995. e-Pub 1995. PMID: 7870140.
149. Okhuysen, PC, Jiang, X, Ye, L, Johnson, PC, Estes, MK. Viral shedding and fecal IgA response after norwalk virus infection. Journal of Infectious Diseases 171(3):566-569, 1995. e-Pub 1995. PMID: 7876602.
150. Okhuysen, PC, Rex, JH, Kapusta, M, Fife, CE. Successful treatment of extensive posttraumatic soft-tissue and renal infections due to apophysomyces elegans. Clinical Infectious Diseases 19(2):329-331, 1994. e-Pub 1994. PMID: 7986910.
151. Scerpella, EG, Okhuysen, PC, Mathewson, JJ, Guerrant, RL, Latimer, E, Lyerly, D, Ericsson, CD. Evaluation of a New Latex Agglutination Test for Fecal Lactoferrin in Travelers' Diarrhea. Journal of Travel Medicine 1(2):68-71, 1994. e-Pub 1994. PMID: 9815314.
152. Okhuysen, PC, DuPont, HL, Sterling, CR, Chappell, CL. Arginine aminopeptidase, an integral membrane protein of the Cryptosporidium parvum sporozoite. Infection and Immunity 62(10):4667-4670, 1994. e-Pub 1994. PMID: 7927738.
153. Okhuysen, PC, Singh, KV, Murray, BE. Susceptibility of β-lactamase-producing enterococci to piperacillin with tazobactam. Diagnostic Microbiology and Infectious Disease 17(3):219-224, 1993. e-Pub 1993. PMID: 8112031.
154. Okhuysen, PC, Crane, JK, Pappas, J. St. Louis Encephalitis in Patients with Human Immunodeficiency Virus Infection. Clinical Infectious Diseases 17(1):140-141, 1993. e-Pub 1993. PMID: 8353238.
155. Okhuysen PC, Flores F, DuPont HL, Flores-Lopez JJ, Mathewson JJ, Perez-Castell F. A Comparative Study of Furazolidone and Placebo in Addition to Oral Rehydration Therapy in the Treatment of Infantile Gastroenteritis. Scan J Gastroentrol(24s):39-46, 1989. e-Pub 1989. PMID: 2694341.

Review Articles

1. Matsuo, T, Okhuysen, PC, Barnett, BJ. Ten Practical Tips for a Successful Presentation at an Infectious Disease Clinical Case Conference. Open Forum Infectious Diseases 12(7), 2025. e-Pub 2025. PMID: 40698035.
2. Kondapi DS, Ramani S, Estes MK, Atmar RL, Okhuysen PC. Norovirus in Cancer Patients: A review. Open Forum Infect Dis 14(8):ofab126, 2021. e-Pub 2021. PMID: 34189156.
3. Flores J, Okhuysen PC. Genetics of susceptibility to infection with enteric pathogens. Curr Opin Infect Dis 22(5):471-6, 2009. e-Pub 2009. PMID: 19633551.
4. Flores J, Okhuysen PC. Enteroaggregative Escherichia coli infection. Curr Opin Gastroenterol 25(1):8-11, 2009. e-Pub 2009. PMID: 19114769.
5. Huang DB, Mohanty A, DuPont HL, Okhuysen PC, Chiang T. A review of an emerging enteric pathogen: enteroaggregative Escherichia coli. J Med Microbiol 55(Pt 10):1303-11, 2006. e-Pub 2006. PMID: 17005776.
6. Okhuysen PC. Current concepts in travelers' diarrhea: epidemiology, antimicrobial resistance and treatment. Curr Opin Infect Dis 18(6):522-6, 2005. e-Pub 2005. PMID: 16258326.
7. Huang DB, Chappell C, Okhuysen PC. Cryptosporidiosis in children. Semin Pediatr Infect Dis 15(4):253-9, 2004. e-Pub 2004. PMID: 15494949.
8. Huang DB, Okhuysen PC, Jiang ZD, DuPont HL. Enteroaggregative Escherichia coli: an emerging enteric pathogen. Am J Gastroenterol 99(2):383-389, 2004. e-Pub 2004. PMID: 15046233.
9. Chappell CL, Okhuysen PC. Cryptosporidiosis. Curr Opin Infect Dis 15(5):523-527, 2002. e-Pub 2002. PMID: 12686887.
10. Okhuysen PC, Chappell CL. Cryptosporidium virulence determinants--are we there yet?. Int J Parasitol 32(5):517-525, 2002. e-Pub 2002. PMID: 11943224.
11. Nannini EC, Okhuysen PC. HIV1 and the gut in the era of highly active antiretroviral therapy. Curr Gastroenterol Rep 4(5):392-398, 2002. e-Pub 2002. PMID: 12228041.
12. Okhuysen PC. Traveler's diarrhea due to intestinal protozoa. Clin Infect Dis 33(1):110-4, 2001. e-Pub 2001. PMID: 11389503.
13. Dasgupta, A, Okhuysen, PC. Pharmacokinetic and other drug interactions in patients with AIDS. Therapeutic Drug Monitoring 23(6):591-605, 2001. e-Pub 2001. PMID: 11802090.
14. Okhuysen, PC, White, AC. Parasitic infections of the intestines. Current opinion in infectious diseases 12(5):467-472, 1999. e-Pub 1999. PMID: 17035813.
15. Okhuysen, PC, Ericsson, CD. Traveler's diarrhea. Current opinion in gastroenterology 8(1):110-114, 1992. e-Pub 1992.
16. Okhuysen, PC, Ericsson, CD. Travelers' diarrhea. Medical Clinics of North America 76(6):1357-1373, 1992. e-Pub 1992. PMID: 1405823.

Professional Educational Materials

1. . Consultant to Rice University - MedMyst - Malaria interactive software (An NIH/CDC funded Science Education Partnership Award SEPA), 2004.
2. . Improving Management and Optimizing Treatment for the HIV Positive Population. Mediimax Communications, 2004.

Editorials

1. Okhuysen PC, Dupont HL. Enteroaggregative Escherichia coli (EAEC): A Cause of Acute and Persistent Diarrhea of Worldwide Importance. J Infect Dis 202(4):503-505, 2010. PMID: 20594108.

Abstracts

1. Abu-Sbeih H, Irshad Q, Wang X, Okhuysen PC, Lum P, Shuttlesworth G, Stroehlein J, Wang Y. Multiple recurrent Clostridium difficine infection is associated with treatment failure and prolonged illness in cancer patients. Programs and abstracts of the 2018 Digestive Diseases Week, June 4, 2018, Chicago, IL, 2018. e-Pub 2018.
2. E Yepez Guevara E, H Yalamanchili H, A Chao A, K Garey K, M Bhatti M, S. Relevance of Clostridium difficile ribotype 014-20 in cancer patients with diarrhea. Program and Abstracts of the 28th European Congress on Clinical Microbiology and Infectious Diseases, Madrid, Spain, April 16-18, 2018. e-Pub 2018.
3. Wang W, Okhuysen PC. Yersinia enterocolitica infections in Cancer Patients: A Case Series. Program and Abstracts IDWeek, San Francisco, CA, October 2-17, 2018, 2018. e-Pub 2018.
4. Okhuysen P, Olvera A. Characterization of enteropathogenic Escherichia coli (EPEC) in cancer patients with diarrhea. Program and Abstracts IDWeek, San Francisco, CA, October 2-7, 2018, 2018. e-Pub 2018.
5. Yalamanchili H, Chao A, Yepez E, Aitken S, Bhatti M, Okhuysen PC. Risk Factors and Clinical Outcomes of Cancer Patients with Clostridium difficile Associated Diarrhea Co-infected with a second pathogen. Program and Abstracts IDWeek 2017, Abstract 1185. October 4-8, San Diego, CA, 2017. e-Pub 2017.
6. Yepez E, Yalamanchili H, Chao A, Garey K, Bhatti M, Aitken S, Okhuysen P. Ribotypes matter. Significance of Clostridium difficile ribotypes in Cancer patients with diarrhea. Program and Abstracts IDWeek 2017, Abstract 1265. October 4-8, San Diego, CA, 2017. e-Pub 2017.
7. Chao A, Yalamanchili H, Yepez E, Bhatti M, Aitken S, Okhuysen PC. Line of Service-Specific Performance and Antibiotic Prescription Habits following Introduction of a Two Step Diagnostic Approach using NAAT Followed by Enzyme Immunoassay in Cancer Patietns with Suspected Clostridium difficile Infection. Program and Abstracts IDWeek 2017, Abstract 1286. October 4-8, San Diego, CA, 2017. e-Pub 2017.
8. Chao A, Bhatti M, Carlin L, Okhuysen PC. Clinical characteristics and molecular epidemiology of diarrhoeagenic Escherichia coli in cancer patients. Program and Abstracts European Congress of Clinical Microbiology and Infectious Diseases 2017, Vienna, Austria, 2017. e-Pub 2017.
9. Malik F, MD, Ghosh N, MPH, Okhuysen P, MD, FIDSA, Daver R, MBBS, MD, Vanichanan J, MD, Carlin L, BS. Clinical and Epidemiological Characteristics of Viral Associated Diarrhea (VAD) in Immunocompromised and Cancer Patients at MD Anderson Cancer Center (MDACC) 2005-2014. Programs and Abstracts ID Week 2016(1215), 2016. e-Pub 2016.
10. Daver RG, Shewale J, Lindsay B, Oundo J, Ochieng B, Saha D, Breimen R, Antonio M, Panchalingam S, Volcik K, Grove-Gaona M, Stine OC, Nataro JP, Kaper J, Levine MM, Kotloff KL, Okhuysen PC. Host Gene Polymorphisms and Susceptibility to Bacterial Enteropathogens in Children Living in Gambia and Kenya. Programs and Abstracts of the American Society for Tropical Medicine and Hygiene 63rd annual meeting, New Orleans LA, 2014. e-Pub 2014.
11. Daver RG, Shewale J, Lindsay B, Oundo J, Ochieng B, Saha D, Breimen R, Antonio M, Panchalingam S, Volcik K, Grove-Gaona M, Stine OC, Nataro JP, Kaper J, Levine MM, Kotloff KL, Okhuysen PC. Host Gene Polymorphisms and Susceptibility to Viral Enteropathogens in Children Living in The Gambia and Kenya. ID Week Programs and Abstracts of the Infectious Diseases Society of America Annual Meeting, Philadelphia PA, 2014. e-Pub 2014.
12. DuPont HL, Okhuysen PC, Chappell CL. Controlled Human Infection Studies in the Development of Vaccines and Therapeutics. The Wellcome Trust, 2013. e-Pub 2013.
13. Okhuysen PC, Lewis DE, Carlin LG, Orozco AF, Gomez DM, Raynor MJ, Jiang ZD, DuPont HL. Analysis of diffusely adhering Escherichia coli (DAEC) and enteroaggregative E. coli (EAEC) adherence to HEp-2 cells by flow cytometry reveals distinct patterns of attachment and cell death caused by isolates from visitors to Mexico and India with travelers’ diarrhea. 49th Infectious Diseases Society of America Annual Meeting, Boston MA, 2011. e-Pub 2011.
14. Cozzi-Lepri A, French M, Baxter J, Okhuysen PC, Plana M, Nehaus J, Landay, A. Resumption of HIV replication in SMART Study patients is associated with monocyte/macrophage derived cytokine and chemokine changes in addition to CD4+ T cell decline. Conference on Retrovirus and Opportunistic Infections (CROI), Boston MA, 2011. e-Pub 2011.
15. Okhuysen, PC. Host genetic susceptibility to ETEC. Symposium presentation. Program and Abstracts of the 59th annual meeting of the American Society for Tropical Medicine and Hygiene, Atlanta, GA, 2010. e-Pub 2010.
16. Flores J, Gonzalez-Estrada A, DuPont HL, Paredes-Paredes M, Mohamed JA, Carlin L, Okhuysen PC. Dispersin Expression by Non-Enteroaggregative Escherichia coli Isolated from US Travelers with Acute Diarrhea Visiting Mexico. Programs and Abstracts of the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Philadelphia PA, 2009. e-Pub 2009.
17. Flores J, Okhuysen PC, Belkind-Gerson J, Gonzalez-Estrada A, Paredes-Paredes M, Mohamed JA, Carlin L, Haley CA, DuPont HL. Incidence of Diarrheagenic Escherichia coli in US Travelers with Acute Diarrhea Visiting Mexico; Emergence of Enteropathogenic E. coli (EPEC) and Enterohemorrhagic E. coli (EHEC) as Causal Agents. Programs and Abstracts of the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Philadelphia PA, 2009. e-Pub 2009.
18. Okhuysen PC, Flores J, Mohamed JA, J Belkind-Gerson J, Jiang ZD, Nair P, FG Martinez Sandoval FG, DuPont HL. Gene Polymorphisms in Molecules involved in the innate immune response to Lipopolysaccharide (LPS) Predispose to Diarrhea in US Travelers to Mexico. Programs and Abstracts of the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Washington DC, 2008. e-Pub 2008.
19. Flores J, DuPont HL, Belkind-Gerson J, Paredes M, Aguirre M, Rojas A, Okhuysen PC. Whole Blood Gamma Interferon Response to Cholera Toxin B and Resistance to Travelers’ Diarrhea. A Pilot Study of Cellular Immunity and ETEC Diarrhea (Poster 1615). Programs and Abstracts of the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Washington DC (Poster 1615), 2008. e-Pub 2008.
20. Paredes M, DuPont HL, Belkind-Gerson J, Flores J, Carlin L, Mohamed JA, Gonzalez-Estrada A, Nair P, Okhuysen PC. Seasonal Influence on the Occurrence of Traveler’s Diarrhea due to Diarrheagenic E. coli. Programs and Abstracts of the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Washington DC (Poster 1613), 2008. e-Pub 2008.
21. Haley CC, DuPont HL, Paredes M, Flores J, Mohamed JA, Belkind-Gerson J, Jiang ZD, Gonzalez A, Martinez Sandoval FG, Okhuysen PC. Prevalence of STEC Associated Diarrhea in US travelers to Mexico. Programs and Abstracts of the 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the Infectious Diseases Society of America (IDSA) 46th Annual Meeting, Washington DC, 2008. e-Pub 2008.
22. Nair P, DuPont HL, Mohamed JA, Flores J, Jiang ZD, Belkind-Gerson J, Martinez-Sandoval F, Okhuysen Nair P, HL DuPont HL, JA Mohamed JA, J Flores J, ZD Jiang ZD, J Belkind-Gerson J, F Martinez-Sandoval F, Okhuysen PC. Epidemiology of Cryptosporidiosis in North American Travelers to Mexico. Program and Abstracts of the 45th Infectious Diseases Society of America Annual Meeting, San Diego CA, 2007. e-Pub 2007.
23. Mohamed JA, DuPont HL, Jiang ZD, Tsai A, Flores J, Belkind-Gerson J, Martinez Sandoval FG, Guo DC, Okhuysen PC. A single nucleotide Polymorphism in the Osteoprotegerin Gene is associated with Traveler’s Diarrhea. Programs and Abstracts of the 45th Infectious Diseases Society of America Annual Meeting, San Diego CA, 2007. e-Pub 2007.
24. Flores J, DuPont HL, Jiang ZD, Belkind-Gerson J, Tsai A, Mohamed JA, Martinez-Sandoval FG, Guo DC, Okhuysen PC. Influence of Host IL-10 Polymorphism on the Development of Traveler’s Diarrhea. Program and Abstracts of the 45th Infectious Diseases Society of America Annual Meeting, San Diego CA, 2007. e-Pub 2007.

Book Chapters

1. Mittal, N, Catinis, C, Lu, Y, Iyer, SP, Okhuysen, PC, Wang, Y. CMV Colitis with Perforation Post Immune Checkpoint Inhibitor Therapy with Multi-Organ Failure, 113-118, 2025.
2. Malek, A, Okhuysen, PC. Infectious Diseases. In: Managing Immunotherapy Related Toxicities. Springer Nature Switzerland AG, 167-195, 2022.
3. Rex, J, Okhuysen PC. Sporothrix shenckii. In: Principles and Practice of Infectious Diseases. Ninth. Elsevier, 2019.
4. DuPont, HL, Okhuysen PC. Shigella and Enteroinvasive E. coli. In: Principles and Practice of Infectious Diseases. Ninth. Elsevier, 2019.
5. DuPont HL, Okhuysen PC. Approach to the Patient with Suspected Enteric Infection. In: Goldman and Cecil Medicine. 26th. Elsevier, 2019.
6. Rex, JH, Okhuysen, PC. Sporothrix schenckii. In: Principles and Practice of Infectious Diseases. Churchill Livingstone, 2920-2924, 2014.
7. Flores, J, Okhuysen, PC. Enterotoxigenic escherichia coli. In: Pathogenic Escherichia coli in Latin Americ. Bentham Science, 84-94, 2010.
8. Navarro-Garcia, F, Elias, WP, Flores, J, Okhuysen, PC. Enteroaggregative escherichia coli. In: Pathogenic Escherichia coli in Latin Americ. Bentham Science, 48-64, 2010.
9. Rex JH, Okhuysen PC. Sporothrix Shenckii. In: Principles and Practice of Infectious Diseases, Seventh Edition. Seventh. Churchill Livingstone, 2009.
10. Petry WA, Snider C, Okhuysen PC. The parasitic pathogens. In: Travelers’ Diarrhea Textbook. 2nd edition. 2nd. Becker, 31-42, 2007.
11. Okhuysen PC, Lee SA, Guerrant RL. Genetic Susceptibility to Enteric Infections; Implications for Endemic and Travelers’ Diarrhea. In: Travelers’ Diarrhea Textbook, 2nd Edition. 2nd. Becker, 153-158, 2007.
12. Rex JH, Okhuysen PC. Sporothrix Shenckii. In: Principles and Practice of Infectious Diseases, Sixth Edition. Sixth. Churchill Livingstone, 2984-2988, 2005.
13. Mead JR, Okhuysen PC. Rationale approaches to treating Cryptosporidium, Cyclospora, Giardia and Entamoeba. In: World Class Parasites: Volume 8. Kluwer Academic, 2004.
14. Chappell, CL, Okhuysen, PC, White, AC. Cryptosporidium Parvum;Infectivity, Pathogenesis and the Host-parasite Relationship. In: Cryptosporidium From Molecules to Disease. Elsevier, 19-49, 2003.
15. Chappell, CL, Okhuysen, PC, DuPont, HL, Sterling, CR, Tzipori, S. Cryptosporidium Parvum Volunteer Study. In: Cryptosporidium From Molecules to Disease. Elsevier, 79-81, 2003.
16. Okhuysen PC, White AC. Parasites. In: Traveler’s Diarrhea. Becker, 47-57, 2003.
17. Chappell, CL, Okhuysen PC. Cryptosporidiosis. In: North American Parasitic Zoonoses. Kluwer Academic, 113-128, 2002.
18. Chappell CL, Okhuysen PC. Cryptosporidiosis in Healthy Volunteers. In: Cryptosporidium: The Analytical Challenge. Royal Society of Chemistry, 62-72, 2001.
19. Ostrosky L, Okhuysen PC. Acute Infectious Diarrhea. In: Conn’s Current Therapy. Sauders WB, 12-18, 2001.
20. Okhuysen PC Chappell CL. Intestinal Protozoa. In: Textbook of Internal Medicine, Fourth Edition. Fourth. Lippincott Raven, 2000.
21. Okhuysen PC. Central and Mainland America. In: Textbook of Travel Medicine, Second edition, 67, 2000.
22. Marshall GD, Okhuysen PC. HIV Infection: Diagnosis and Early Management. In: Current Practice of Medicine. Current Medicine, 1999.
23. Rex JR, Okhuysen PC. Sporothrix Shenckii. In: Principles and Practice of Infectious Diseases. Fifth. Churchill Livingston, 2695-2698, 1999.
24. Okhuysen PC, Chappell, CL. Intestinal Protozoa. In: Textbook of Internal Medicine, Third Edition. Third. Lippincott Raven, 1791-1794, 1997.
25. Okhuysen PC, DuPont HL. Shigella and Enteroinvasive E coli. In: Principles and Practice of Infectious Diseases. Tenth. Elsevier.
26. Spec, Okhuysen PC, Rex, J. Sporothrix Shenckii. In: Principles and Practice of Infectious Diseases. Tenth. Elsevier.

Letters to the Editor

1. Cabada MM, Okhuysen PC, Jr WA. Enteropathogens and chronic illness in returning travelers. N Engl J Med 369: 783, 2013.
2. Muller, TB, Frost, FJ, Craun, GF, Calderon, RL, Chappell, CL, Okhuysen, PC, Dann, SM. Serological responses to Cryptosporidium infection [1] (multiple letters). Infection and Immunity 69: 1974-1975, 2001.
3. Frost, FJ, Craun, GF, Okhuysen, PC, Chappell, CL, DuPont, HL, Sterling, CR, Jakubowski, W. Serologic response to human Cryptosporidium infections (multiple letters). Infection and Immunity 66: 4008-4009, 1998.