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Patrick P. Lin, M.D.

Present Title & Affiliation

Primary Appointment

Associate Professor, Division of Surgery, University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Professor, Orthopaedic Surgery, Division of Surgery, University of Texas - Houston Health Science Center, Houston, TX
Assistant Professor, Orthopedic Surgery, Baylor College of Medicine, Houston, TX

Office Address

University of Texas MD Anderson Cancer Center
1400 Pressler Street
Department of Orthopaedic Oncology
Unit Number: 1448
Houston, TX 77030
Room Number: FCT10.5042
Phone: (713) 745-0088
Fax: (713) 792-8448

Education & Training

Degree-Granting Education

1990 Stanford University School of Medicine, Stanford, CA, MD, Medicine
1984 Harvard University, Cambridge, MA, BA, Biochemical Sciences

Postgraduate Training

7/1996-7/1998 Clinical Fellowship, Orthopaedic Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, John Healey, M.D.
7/1991-7/1996 Clinical Residency, Orthopaedic Surgery, University of North Carolina Hospitals, Chapel Hill, NC, Frank C. Wilson, M.D.
7/1990-7/1991 Clinical Internship, General Surgery, University of North Carolina Hospitals, Chapel Hill, NC, George F. Sheldon, M.D.

Board Certifications

1/2012 American Board of Orthopaedic Surgery

Experience/Service

Academic Appointments

Assistant Professor, Department of Orthopedic Oncology, Division of Surgery, University of Texas M.D. Anderson Cancer Center, Houston, TX, 1/1998-1/2004

Administrative Appointments/Responsibilities

Director of Research, Department of Surgical Oncology, Section of Orthopaedic Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 1/2001-present
Director of Physician Assistants and Nurse Practitioners, Department of Surgical Oncology, Section of Orthopaedic Oncology, Division of Surgery, University of Texas M.D. Anderson Cancer Center, Houston, TX, 1/2000-1/2001
Designer and Manager of Internet Web Page, Department of Surgical Oncology, Section of Orthopaedic Oncology, Division of Surgery, University of Texas M.D. Anderson Cancer Center, Houston, TX, 1/1999-1/2001

Other Appointments/Responsibilities

Volunteer Faculty Member, University of Texas-Houston Health Science Center, Houston, TX, 1/2002-present
Instructor, University of North Carolina School of Medicine, Chapel Hill, NC, 1/1992-12/1992

Institutional Committee Activities

Member, Study Section Review Committee for the Sister Institution Network Funding Program, 4/2011-4/2014
Member, Value Analysis Team, Perioperative Enterprise, 5/2008-8/2014
Member, Clinical Research Committee I, 1/2005-1/2007
Member, Clinical Research Committee II, 1/2004-1/2005
Alternate Member, Operating Room Committee, 1/2003-1/2006
Member, Briscoe PA Award Committee, 1/2003

Honors and Awards

2013 Top Doctor, Southeast Texas, Castle Connolly
2012 U.S. News Top Orthopedic Surgeon, U.S. News & World Report
2008 Top Doctor, Castle Connolly
1996 American Orthopaedic Association-Zimmer Resident Research Award
1987 Radiation Research Society Student Travel
1983 Phi Beta Kappa
1981 Harvard Detur Prize
1980 High School Valedictorian
1980 National Merit Scholarship

Selected Publications

Peer-Reviewed Original Research Articles

1. Satcher RL, Lin P, Huran N, Feng L, Moon B, Lewis VO. The benefit of surgical management of colorectal carcinoma bone metastases. J Solid Tumors. In Press.
2. Takeuchi A, Lewis VO, Satcher RL, Moon BS, Lin PP. What are the factors that affect survival and relapse after local recurrence of osteosarcoma? Clin Ortho Relat Res. In Press. PMID: 24980644.
3. Krygier J, Lewis VO, Cannon C, Satcher RL, Lin PP. Operative management of metastatic melanoma in bone may require en bloc resection of disease. Clin Orthop Relat Res. e-Pub 7/2014. PMID: 24989125.
4. Janku F, Vibat CRT, Kosco K, Holley VR, Cabrilo G, Meric-Bernstam F, Stepanek VM, Lin PP, Leppin L, Hassaine L, Poole JC, Kurzrock R, Erlander MG. BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease. Oncotarget 5(11):3607-3610, 6/2014. PMID: 25003820.
5. Kawaguchi A, Sun T, Lin PP, Deavers M, Harun N, Lewis VO. Does ifosfamide therapy improve survival of patients with dedifferentiated chondrosarcoma? Clin Orthop Relat Res 472(3):983-989, 2014. PMID: 24197392.
6. Kawaguchi S, Weiss I, Lin PP, Huh WW, Lewis VO. Radiation therapy is associated with fewer recurrences in mesenchymal chondrosarcoma. Clin Orthop Relat Res 472(3):856-864, 2014. PMID: 23709273.
7. Xing Z, Moon BS, Satcher RL, Lin PP, Lewis VO. A long femoral stem is not always required in hip arthroplasty for patients with proximal femur metastases. Clin Orthop Relat Res 471(5):1622-1627, 5/2013. PMCID: PMCPMC3613523.
8. Moon BS, Gilbert NF, Cannon CP, Lin PP, Lewis VO. Distal femur allograft prosthetic composite reconstruction for short proximal femur segments following tumor resection. Adv Orthop:5 pages, 2013. PMID: 24349792.
9. Wang WL, Datz D, Araujo DM, Ravi V, Ludwig JA, Trent JC, Patel SR, Lin PP, Guadagnolo A, Lopez-Terrada D, Dei Tos AP, Lewis VO, Lev D, Pollock RE, Zagars GK, Benjamin RS, Madewell JE, Lazar AJ. Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and preoperative radiation therapy. Clin Sarcoma Res. e-Pub 12/2012. PMID: 23272660.
10. Chen LL, Chen X, Choi H, Sang H, Chen LC, Zhang H, Gouw L, Andtbacka RH, Chan BK, Rodesch CK, Jimenez A, Cano P, Jones KA, Oyedeji CO, Martins T, Hill HR, Schumacher J, Willmore C, Scaife CL, Ward JH, Morton K, Randall RL, Lazar AJ, Patel S, Trent JC, Frazier ML, Lin P, Jensen P, Benjamin RS. Exploiting antitumor immunity to overcome relapse and improve remission duration. Cancer Immunol and Immunother 61(7):1113-1124, 7/2012.
11. Lin PP, Alfawareh MD, Takeuchi A, Moon BS, Lewis VO. Sixty percent 10-year survival of patients with chondrosarcoma after local recurrence. Clin Orthop Relat Res 470(3):670-676, 3/2012.
12. Satcher RL, Lin P, Harun N, Moon B, Feng L, Lewis VO. Surgical management of appendicular skeletal metastases in thyroid carcinoma. Int J Surg Oncol:12 pages, 2012.
13. Moon B, Lin P, Satcher R, Lewis V. Simultaneous nailing of skeletal metastases: Is the mortality really that high? Clin Orthop Relat Res 469(8):2367-2370, 8/2011.
14. Kim JH, Kang HG, Kim JR, Lin PP, Kim HS. Minimally invasive surgery of humeral metastasis using flexible nails and cement in high-risk patients with advanced cancer. Surgical Oncology 20(1):e32-7, 3/2011. e-Pub 9/2010. PMID: 20870403.
15. Lin PP, Wang Y, Lozano G. Mesenchymal stem cells and the origin of Ewing's sarcoma. Sarcoma. e-Pub 10/2010. PMCID: PMC2952797.
16. Lin PP, Moussallem CD, Deavers MT. Secondary chondrosarcoma. J Am Acad Orthop Surg 18(10):608-615, 10/2010.
17. Merriman DJ, Deavers MT, Czerniak B, Lin PP. Massive desmoplastic fibroblastoma with scapular invasion - A case report. Orthopedics 11:33, 8/2010.
18. Gilbert NF, Yasko AW, Oates SD, Lewis VO, Cannon CP, Lin PP. Allograft-prosthetic composite reconstruction of the proximal part of the tibia. An analysis of the early results. J Bone Joint Surg Am 91(7):1646-56, 7/2009. PMID: 19571087.
19. Barnea Y, Lin P, Reece G. Modified tibial turn-up fillet flap for repair of extensive composite defects of the thigh. Ann Plast Surg 62:170-172, 2/2009.
20. Gilbert NF, Cannon CP, Lin PP, Lewis VO. Soft tissue sarcoma. J Am Acad Ortho Surg 17:40-47, 1/2009.
21. Cannon CP, Lin PP, Lewis VO, Yasko AY. Management of radiation-associated fractures. J Am Acad Orthop Surg 16:541-549, 9/2008.
22. Cannon CP, Mirza AN, Lin PP, Lewis VO, Yasko AW. Proximal femoral endoprosthesis for the treatment of metastatic disease. Orthopedics (Online) 31:361, 4/2008.
23. Lin PP, Brown C, Raymond AK, Deavers MT, Yasko AW. Aneurysmal bone cysts recur at juxtaphyseal locations in skeletally immature patients. Clin Orthop Relat Res 466. e-Pub 1/2008.
24. Gupta GR, Yasko AW, Lewis VO, Cannon CP, Raymond AK, Pate S, Lin PP. Risk of local recurrence after deltoid-sparing resection for osteosarcoma of the proximal humerus. Cancer 115:3767-3773, 2008.
25. Pisters PW, Pollock RE, Lewis VO, Yasko AW, Cormier JN, Respondek PM, Feig BW, Hunt KK, Lin PP, Zagars G, Wei C, Ballo MT. Long-term results of prospective trial of surgery alone with selective use of radiation for patients with T1 extremity and trunk soft tissue sarcomas. Ann Surg 246:675-682, 10/2007.
26. Lin PP, Mirza AN, Lewis VO, Cannon CP, Tu SM, Tannir NM, Yasko AW. Patient survival after surgery for osseous metastases from renal cell carcinoma. J Bone Joint Surg Am 89:1794-1801, 8/2007.
27. Normand, AN, Cannon CP, Lewis VO, Lin PP, Yasko AW. Curettage of biopsy-diagnosed grade 1 periacetabular chondrosarcoma. Clin Orthop Relat Res 459:146-149, 6/2007.
28. Yasko AW, Rutledge J, Lewis VO, Lin PP. Disease-and recurrence-free survival after surgical resection of solitary bone metastases of the pelvis. Clin Orthop Relat Res 459:128-132, 6/2007.
29. Cannon CP, Lin PP, Lewis VO, Yasko AW. Acetabular outcome after hip hemiarthroplasty in patients with tumors. Clin Orthop Relat Res 457:183-187, 4/2007.
30. Costelloe CM, Kumar R, Yasko AW, Murphy WA, Stafford RJ, Lewis VO, Lin PP, Madewell JE. Imaging characteristics of locally recurrent tumors of bone. Am J Roentgenol 188:855-863, 3/2007.
31. Lin PP, Jaffe N, Herzog CE, Costelloe CM, Deavers MT, Kelly JS, Patel SR, Madewell JE, Lewis VO, Cannon CP, Benjamin RS, Yasko AW. Chemotherapy response is an important predictor of local recurrence in Ewing's sarcoma. Cancer 109:603-611, 2/2007.
32. Lin PP, Pino ED, Normand AN, Deavers MT, Cannon CP, Ballo MT, Pisters PW, Pollock RE, Lewis VO, Zagars GK, Yasko AW. Periosteal margin in soft-tissue sarcoma. Cancer 109:598-602, 2/2007.
Other Articles
1. Costelloe CM, Yasko AW, Murphy WA, Kumar R, Lewis VO, Lin PP, Stafford J, Madewell JE. MRI of locally recurrent soft tissue tumors of the musculoskeletal system. The Internet Journal of Radiology 5(2), 2007.

Book Chapters

1. Dirk SM, Lin P, Buerger S, Cicotte KN, Reece G, Hedberg-Dirk E. Biomimetic approaches to peripheral neuroprosthetic interfaces (Volume 1: Bioinspired Materials). In: Handbook of Biomimetics and Bioinspiration. 9. Ed(s) Jabbari E, Khademhosseini A, Kim DH. World Scientific Publishing Co. Singapore, 121-151, 2014. ISBN: 978-981-4354-92-9.
2. Costelloe CM, Ueno NT, Lin PP, Yu TK, Hayashi N, Madewell JE. Bone metastases. In: Oncologic Imaging: A Multidisciplinary Approach. Ed(s) Silverman, PM. Elsevier: Philadelphia, 591-609, 2012. ISBN: 978-1-4377-2232-1.
3. Lin PP. Sarcomas of bone. In: Advanced Therapy in Surgical Oncology. Ed(s) RE Pollock, SA Curley, MI Ross, NP Perrier. BC Decker, Inc. Canada, 617-635, 2008.
4. Lin PP, Healey JH. Sarcomas of bone. In: Surgical Oncology, Contemporary Principles & Practice. Ed(s) KI Bland, JM Daly, CP Karakousis. McGraw-Hill: New York, 1015-1053, 2001.

Books (edited and written)

1. Lin, PP. Ed(s) Lin PP, Patel S. Bone Sarcoma. In: MD Anderson Cancer Care Series. Series Ed(s) Buzdar AU, Freedman RS. Springer: New York, 2013. ISBN: 978-1-4614-5193-8.
2. Wilson FC, Lin PP, editors. General Orthopaedics. MacGraw-Hill, 1997.

Manuals, Teaching Aids, Other Teaching Publications

1. Randall L, Aboulafia A, Morris C, Lin P (Section Editor), Benevenia J, Holt G. Orthopaedic Knowledge Update: Musculoskeletal Tumors 3. Ed(s) JS Biermann. American Academy of Orthopaedic Surgeons: Rosemont, 2014. PMID: 978-0-89203-968-5.

Grant & Contract Support

Title: A genome-wide screen for cooperating mutations in Ewing sarcoma
Funding Source: Children Sarcoma Initiative and the Triumph Over Kid Cancer Foundation
Role: Principal Investigator
Duration: 5/1/2014 - 4/30/2016

Last updated: 7/24/2014