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Paul J. Chiao, Ph.D.

Present Title & Affiliation

Primary Appointment

Professor, Department of Molecular and Cellular Oncology, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Professor, Department of Surgical Oncology - Research, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston
Professor, U of Texas Graduate School of Biomedical Sciences, Houston, TX

Office Address

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center
1515 Holcombe Boulevard
Unit Number: 108
Houston, TX 77030
Room Number: Y8.6085, Laboratory Y8.6041 - Y8.6049

Education & Training

Degree-Granting Education

1991 University of Texas Health Science Center, Houston, TX, PHD, Cancer Biology
1984 The University of Iowa, Iowa City, IA, BS, Microbiology

Postgraduate Training

1991-1995 Postdoctoral Fellow, Molecualr Biology and VIrology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA, Dr. Inder M. Verma

Selected Publications

Peer-Reviewed Original Research Articles

1. Peng B, Lee, AJ, Wang Z, Ling J, Jin W, Yang K, Zhang R, Chang Z, Shim D, Wang H, Fleming JB, Zheng H, Sun SC, Chiao PJ. Defective feedback regulation of NF-kappaB underlies Sjogren's Syndrome in the mice with mutated kappaB enhancers of the lkappaBalpha promoter. Proc Natl Acad Sci USA 107(34):15193-15198, 8/2010. PMID: 20696914.
2. Melisi D, Xia Q, Paradiso G, Ling J, Moccia T, Carbone C, Budillon A, Abbruzzese JL, Chiao PJ. Modulation of pancreatic cancer chemoresistance by inhibition of TAK1. J Natl Cancer Inst 103(15):1190-204, 8/2011. e-Pub 7/2011. PMCID: PMC3149044.
3. Ling JH, Kang Y, Zhao R, Xia QH, Lee DF, Chang Z, Li J, Peng B, Fleming JB, Wang H, Liu J, Lemischka IR, Hung MC, Chiao PJ. KrasG12D-induced IKK2/B/NF-kB activation by IL-1alpha and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell. In Press.

Last updated: 1/6/2012