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Qing Ma, Ph.D.

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Stem Cell Transplantation - Research, Division of Cancer Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX
Faculty Member, University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX

Office Address

The University of Texas M. D. Anderson Cancer Center
1515 Holcombe Blvd.
Unit Number: 900
Houston, TX 77030
Room Number: SCRB1-3.3027
Phone: (713) 563-3327
Fax: (713) 563-3338
Email: qma@mdanderson.org

Education & Training

Degree-Granting Education

1995 Thomas Jefferson University, Philadelphia, PA, PHD, Genetics
1988 Fudan University, Shanghai, China, BS, Biochemistry

Postgraduate Training

2001-2002 Research Fellowship, Transplantation, Fred Hutchinson Cancer Research Center, Seattle, WA, Rainer Storb, M.D.
1995-2001 Research Fellowship, Immunology, Harvard Medical School, Boston, MA, Timothy Springer, Ph.D.

Selected Publications

Peer-Reviewed Original Research Articles
1. Kim TK, St. John LS, Wieder ED, Khalili J, Ma Q, Komanduri KV. Human late memory CD8+ T cells have a distinct cytokine signature characterized by CC-chemokine production without IL-2 production. Journal of Immunology. In Press.
2. Li D, Molldrem JJ, Ma Q. LFA-1 Regulates CD8+ T Cell Activation via T Cell Receptor-mediated and LFA-1-mediated Erk1/2 Signal Pathways. J Biol Chem 284(31):21001-10, 7/31/2009. e-Pub 5/29/2009. PMID: 19483086.
3. Wang Y, Li D, Nurieva R, Yang J, Sen M, Carreņo R, Lu S, McIntyre BM, Molldrem JM, Legge GB, Ma Q. LFA-1 affinity regulation is necessary for the activation and proliferation of naīve T cells. J Biol Chem 284(19):12645-53, 5/8/2009. e-Pub 3/18/2009. PMCID: PMC2675993.
4. Wang Y, Li D, Jones D, Bassett R, Sale GE, Khalili J, Komanduri KV, Couriel DR, Champlin RE, Molldrem JJ, Ma Q.. Blocking LFA-1 activation with lovastatin prevents graft-versus-host disease in mouse bone marrow transplantation. Biol Blood Marrow Transplant doi:10.1016/j.bbmt.2009.08.013, 2009.
5. Ma Q, Gooley TA, Storb RF. CCR5 expression on cells from HLA-matched unrelated marrow donors and graft-versus-host disease. Biology of Blood Marrow Transplantation DOI: 10.1016/j.bbmt.2009.05.003., 2009.
6. Freedman RS, Ma Q, Wang E, Gallardo ST, Gordon IO, Shin JW, Jin P, Stroncek D, Marincola FM. Migration deficit in monocyte-macrophages in human ovarian cancer. Cancer Immunol Immunother 57(5):635-45, 5/2008. e-Pub 10/10/2007. PMID: 17926037.
7. Carreņo R, Li D, Sen M, Nira I, Yamakawa T, Ma Q, Legge GB. A mechanism for antibody-mediated outside-in activation of LFA-1. J Biol Chem 283(16):10642-8, 4/18/2008. e-Pub 1/16/2008. PMID: 18199751.
8. Toba Y, Tiong JD, Ma Q, Wray S. CXCR4/SDF-1 system modulates development of GnRH-1 neurons and the olfactory system. Dev Neurobiol 68(4):487-503, 3/2008. PMID: 18188864.
9. Kaul M, Ma Q, Medders KE, Desai MK, Lipton SA. HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection. Cell Death Differ 14(2):296-305, 2/2007. e-Pub 7/14/2006. PMID: 16841089.
10. Wang X, Deavers M, Patenia R, Bassett RL, Jr, Mueller P, Ma Q, Wang E, Freedman RS. Monocyte/macrophage and T-cell infiltrates in peritoneum of patients with ovarian cancer or benign pelvic disease. J Transl Med 4:30, 2006. PMCID: PMC1550428.
11. Lu S, Wieder E, Komanduri K, Ma Q, Molldrem JJ. Vaccines in Leukemia. Adv Pharmacol 51:255-70, 2004. PMID: 15464913.
12. Ma Q, Shimaoka M, Lu C, Jing H, Carman CV, Springer TA. Activation-induced conformational changes in the I domain region of lymphocyte function-associated antigen 1. J Biol Chem 277(12):10638-41, 3/22/2002. e-Pub 1/15/2002. PMID: 11792712.
13. Ma Q, Jones D, Springer TA. The chemokine receptor CXCR4 is required for the retention of B-lineage and granulocytic precursors within the bone marrow microenvironment. Immunity 10(4):463-71, 4/1999. PMID: 10229189.
14. Parolin C, Borsetti A, Choe H, Farzan M, Kolchinsky P, Heesen M, Ma Q, Gerald C, Palu G, Dorf ME, Springer T, Sodroski J. Use of Murine CXCR-4 as a second receptor by some T-cell-tropic human imunnodeficiency virus. J Virol 72(2):1652-6, 2/1998. PMCID: PMC124650.
15. Ma Q, Jones D, Borghesani PR, Segal RA, Nagasawa T, Kishimoto T, Bronson RT, Springer TA. Impaired B-lymphopoiesis, myelopiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc Natl Acad Sci USA 95(16):9448-53, 1998. PMCID: PMC21358.
16. Siracusa LD, McGrath R, Ma Q, Moskow JJ, Manne J, Christner PJ, Buchberg AM, Jimenez SA. A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation. Genome Res 6(4):300-13, 4/1996. PMID: 8723723.
17. Ma Q, Alder H, Nelson KK, Chatterjee D, Gu Y, Nakamura T, Canaani E, Croce, C,M, Siracusa LD, Buchberg AM. Analysis of the murine ALLl-1gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases. Proc Natl Acad Sci U S A 9(13):6350-4, 7/1/1993. PMCID: PMC46926.

Last updated: 9/27/2009