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R. Jason Stafford, Ph.D.

Present Title & Affiliation

Primary Appointment

Section Chief of MR and Ultrasound Physics, Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Associate Professor, Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Faculty, The University of Texas Health Sciences Center and the University of Texas MD Anderson Cancer Center Graduate School of Biomedical Sciences, Houston, TX

Bio Statement

 R. Jason Stafford, PhD, DABR is an Associate Professor with tenure and is Chief of the Section of MRI and Ultrasound Physics in the Department of Imaging Physics at the MD Anderson Cancer Center.  He is board certified in diagnostic medical physics and has been on the clinical faculty since 2002.

 Dr. Stafford received his training and doctorate degree in Medical Physics from the Health Science Center at Houston and MD Anderson Cancer Center Graduate School of Biomedical Sciences in 2001.  His research was the design and validation of fast magnetic resonance imaging techniques for monitoring focused ultrasound thermal therapy.  The work garnered awards locally (MD Anderson Alfred Knudson Outstanding Dissertation Award and the Aaron M. Blanchard Research Award in Medical Physics) and nationally (American College of Medical Physics Graduate Student Award and first place in the American Association of Physicists in Medicine John C. Cameron Young Investigator competition).

Dr. Stafford has over 81 peer reviewed publications, has served as primary or co-investigator and several grants, and speaks at national and international meetings.  His research interests lie primarily in the use of magnetic resonance imaging for guidance of oncologic interventions and therapies.  Over the years, much of this research has translated into clinical services, which he now supports at MD Anderson Cancer Center. He is the President-Elect for the Society for Thermal Medicine.

He has mentored five graduate students and six post-doctoral fellows over the last ten years as well as lectures and coordinates in core GSBS courses at MDACC.


Research Interests

  • Magnetic Resonance Imaging
  • Image-Guided Interventions
  • Image-Guided Therapy
  • Thermal Therapy

Education & Training

Degree-Granting Education

2001 The University of Texas Health Science Center at Houston and MD Anderson Cancer Center Graduate School of Biomedical Sciences, Houston, TX, PHD, Medical Physics
1996 California State University, Fresno, CA, MS, Physics
1994 California State University, Fresno, CA, BS, Physics

Board Certifications

2005 American Board of Radiology (Diagnostic Radiological Physics)

Selected Publications

Peer-Reviewed Original Research Articles

1. Maier F, Fuentes D, Weinberg JS, Hazle JD, Stafford RJ. Robust phase unwrapping for MR temperature imaging using a magnitude-sorted list, multi-clustering algorithm. Magn Reson Med. e-Pub 5/2014. PMID: 24809984.
2. Melancon MP, Zhou M, Zhang R, Xiong C, Allen P, Wen X, Huang Q, Wallace M, Myers JN, Stafford RJ, Liang D, Ellington AD, Li C. Selective Uptake and Imaging of Aptamer- and Antibody-Conjugated Hollow Nanospheres Targeted to Epidermal Growth Factor Receptors Overexpressed in Head and Neck Cancer. ACS Nano. e-Pub 4/2014. PMID: 24754567.
3. Huang SY, Abdelsalam ME, Harmoush S, Ensor JE, Chetta JA, Hwang KP, Stafford RJ, Madoff DC, Avritscher R. Evaluation of liver fibrosis and hepatic venous pressure gradient with MR elastography in a novel swine model of cirrhosis. J Magn Reson Imaging 39(3):590-7, 3/2014. e-Pub 11/2013. PMID: 24532376.
4. Taylor BA, Hwang KP, Hazle JD, Stafford RJ. Autoregressive moving average modeling for spectral parameter estimation from a multi-gradient echo chemical shift acquisition. Med Phys 36(3):793-803, 3/2009. PMCID: PMC2736745.
5. Schwartz JA, Shetty AM, Price RE, Stafford RJ, Wang JC, Uthamanthil RK, Pham K, McNichols RJ, Coleman CL, Payne JD. Feasibility study of particle-assisted laser ablation of brain tumors in orthotopic canine model. Cancer Res 69(4):1659-67, 2/2009. e-Pub 2/2009. PMID: 19208847.
6. Carpentier A, McNichols RJ, Stafford RJ, Itzcovitz J, Guichard JP, Reizine D, Delaloge S, Vicaut E, Payen D, Gowda A, George B. Real-time magnetic resonance-guided laser thermal therapy for focal metastatic brain tumors. Neurosurgery 1 Suppl 1: ONS21-8; discussion ONS28-9, 7/2008.
7. Taylor BA, Hwang KP, Elliott AM, Shetty A, Hazle JD, Stafford RJ. Dynamic Chemical Shift Imaging for Image-Guided Thermal Therapy: Analysis of Feasibility and Potential. Med Phys 35(2):793-803, 2/2008. PMID: 18383702.
8. Shetty AM, Stafford RJ, Elliott AM, Kassouf W, Brown GA, Stephens LC, Tinkey PT, Bidaut L, Pisters LL, Hazle JD. Magnetic resonance imaging assessment of a convective therapy delivery paradigm in a canine prostate model. J Magn Reson Imaging 26:1672-1677, 12/2007.
9. Stafford RJ, Price RE, Diederich CJ, Kangasniemi M, Olsson LE, Hazle JD. Interleaved echo-planar imaging for fast multiplanar magnetic resonance temperature imaging of ultrasound thermal ablation therapy. J Magn Reson Imaging 20(4):706-714, 10/2004. PMID: 15390144.
10. Hirsch LR, Stafford RJ, Bankson JA, Sershen SR, Rivera B, Price RE, Hazle JD, Halas NJ, West JL. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc Natl Acad Sci U S A 100(23). e-Pub 11/2003. PMID: 14597719.
11. Stafford RJ, Hazle JD, Glover GH. Monitoring of high-intensity focused ultrasound-induced temperature changes in vitro using an interleaved spiral acquisition. Magn Reson Med 43(6):909-912, 6/2000. PMID: 10861889.
12. Stafford RJ, Kallel F, Price RE, Cromeens DM, Krouskop TA, Hazle JD, Ophir J. Elastographic imaging of thermal lesions in soft tissue: a preliminary study in vitro. Ultrasound Med Biol 24(9):1449-1458, 1998. PMID: 10385966.

Last updated: 12/11/2014