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Reza J. Mehran, CD, SBStJ, M.D.C.M., MSc, FRCSC, FACS

Present Title & Affiliation

Primary Appointment

Professor, Department of Thoracic and Cardiovascular Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

1989 McGill University, Montreal, Canada, MS, Experimental Surgery
1986 McGill University, Montreal, Canada, MD, Doctor of Medicine

Postgraduate Training

7/1992-6/1995 Resident, Cardiovascular and Thoracic Surgery, University of Montreal, Montreal, Canada, Dr. Pierre Page
7/1986-6/1991 Resident, General Surgery, McGill University, Montreal, Canada, Dr. Jonathan Meakins

Board Certifications

2002 American Board of Surgery
1995 Royal College of Surgeons of Canada, Thoracic Surg
1995 Fellow, American College of Surgeons
1991 Royal College of Surgeons of Canada, General Surgery
1991 Certificat de Specialiste de la Province de Quebec
1991 Medical Council of Canada
1991 National Board of Medical Examiners

Experience/Service

Institutional Committee Activities

Member, Promotion and Mid Tenure Review Committee - Thoracic Head & Neck Medical Oncology, 2007-present

Honors and Awards

2006 The Surgery Chief Resident Surgical Teaching Award, The University of Texas - Houston Medical School
2003 Resident Teaching Award, University of New Mexico
2000 The Canadian Peacekeeping Medal, Governor General of Canada, Mrs. Adrian Clark
1999 The Canadian Decoration
1998-present Order of St Francis d'Assisi
1997-present Order of St Lazarus of Jerusalem
1997-present Serving Brother, Most Venerable Order of Saint John of Jerusalem
1997 Chief of Defense Staff Commendation Award
1996 Commander's Commendation Award
1996 NATO Service Medal, former Yugoslavia
1994 Chief of Defense Staff Commendation Award
1993 United Nation Protection Force Service Medal, former Yugoslavia
1990 Research Prize, Quebec Society of Plastic Surgery
1989 Davis and Geck Research Award
1986 Lange Medical Publication Award

Professional Memberships

American Association for Thoracic Surgery
Member, 5/2009-present
American College of Surgeons
Member, 1999-present
American Radium Society
Member, 2006-present
American Thoracic Association
Member, 2005-present
General Thoracic Surgical Club
Member, 1999-present
International Association for the Study of Lung Cancer
Member, 2005-present
Local Chapter of American College of Surgeons, Houston, TX
Member, 2004-present
Society of Thoracic Surgeons
Member, 1999-present
Southern Thoracic Surgical Association
Member, 12/2008-present
Southern Thoracic Surgical Association
Member, 2005-present

Selected Publications

Peer-Reviewed Original Research Articles
1. Gomez DR, Hong DS, Allen PK, Welsh JS, Mehran RJ, Tsao AS, Liao Z, Bilton SD, Komaki R, Rice DC. Patterns of failure, toxicity, and survival after extrapleural pneumonectomy and hemithoracic intensity-modulated radiation therapy for malignant pleural mesothelioma. J Thorac Oncol 8(2):238-45, 2/2013. PMID: 23247629.
2. Sepesi B, Swisher SG, Walsh GL, Correa A, Mehran RJ, Rice D, Roth J, Vaporciyan A, Hofstetter WL. Omental reinforcement of the thoracic esophagogastric anastomosis: An analysis of leak and reintervention rates in patients undergoing planned and salvage esophagectomy. J Thorac Cardiovasc Surg 144(5):1146-51, 11/2012. e-Pub 8/28/2012. PMID: 22939861.
3. Blackmon SH, Stephens EH, Correa AM, Hofstetter W, Kim MP, Mehran RJ, Rice DC, Roth JA, Swisher SG, Walsh GL, Vaporciyan AA. Predictors of Recurrent Pulmonary Metastases and Survival After Pulmonary Metastasectomy for Colorectal Cancer. Ann Thorac Surg. e-Pub 10/10/2012. PMID: 23063195.
4. Ajani JA, Correa AM, Hofstetter WL, Rice DC, Blum MA, Suzuki A, Taketa T, Welsh J, Lin SH, Lee JH, Bhutani MS, Ross WA, Maru DM, Macapinlac HA, Erasmus J, Komaki R, Mehran RJ, Vaporciyan AA, Swisher SG. Clinical parameters model for predicting pathologic complete response following preoperative chemoradiation in patients with esophageal cancer. Ann Oncol 23(10):2638-42, 10/2012. e-Pub 7/24/2012. PMCID: PMC3457750.
5. Marks JL, Hofstetter W, Correa AM, Mehran RJ, Rice D, Roth J, Walsh G, Vaporciyan A, Erasmus J, Chang J, Maru D, Lee JH, Lee J, Ajani JA, Swisher SG. Salvage Esophagectomy After Failed Definitive Chemoradiation for Esophageal Adenocarcinoma. Ann Thorac Surg. e-Pub 8/23/2012. PMID: 22921233.
6. Blackmon SH, Correa AM, Skoracki R, Chevray PM, Kim MP, Mehran RJ, Rice DC, Roth JA, Swisher SG, Vaporciyan AA, Yu P, Walsh GL, Hofstetter WL. Supercharged Pedicled Jejunal Interposition for Esophageal Replacement: A 10-Year Experience. Ann Thorac Surg. e-Pub 8/28/2012. PMID: 22939245.
7. Chang JY, Liu H, Balter P, Komaki R, Liao Z, Welsh J, Mehran RJ, Roth JA, Swisher SG. Clinical outcome and predictors of survival and pneumonitis after stereotactic ablative radiotherapy for stage I non-small cell lung cancer. Radiat Oncol 7:152, 2012. e-Pub 9/10/2012. PMCID: PMC3444889.
8. Mehran RJ. Lung cancer: an update on current surgical strategies. Tex Heart Inst J 39(6):844-5, 2012. PMID: 23304030.
9. Harvin JA, Lahat G, Correa AM, Lee J, Maru D, Ajani J, Marom EM, Welsh J, Bhutani MS, Walsh G, Roth J, Mehran R, Vaporciyan A, Rice D, Swisher S, Hofstetter W. Neoadjuvant chemoradiotherapy followed by surgery for esophageal adenocarcinoma: Significance of microscopically positive circumferential radial margins. J Thorac Cardiovasc Surg. e-Pub 12/13/2011. PMID: 22172216.
10. Kim JY, Correa AM, Vaporciyan AA, Roth JA, Mehran RJ, Walsh GL, Rice DC, Ajani JA, Maru DM, Bhutani MS, Welsh J, Marom EM, Swisher SG, Hofstetter WL. Does the Timing of Esophagectomy After Chemoradiation Affect Outcome? Ann Thorac Surg. e-Pub 9/29/2011. PMID: 21962263.
11. Brouquet A, Vauthey JN, Contreras CM, Walsh GL, Vaporciyan AA, Swisher SG, Curley SA, Mehran RJ, Abdalla EK. Improved survival after resection of liver and lung colorectal metastases compared with liver-only metastases: a study of 112 patients with limited lung metastatic disease. J Am Coll Surg 213(1):62-9, 7/2011. PMID: 21700179.
12. Gomez DR, Cox JD, Roth JA, Allen PK, Wei X, Mehran RJ, Kim JY, Swisher SG, Rice DC, Komaki R. A prospective phase 2 study of surgery followed by chemotherapy and radiation for superior sulcus tumors. Cancer. e-Pub 6/28/2011. PMID: 21713767.
13. Stephens EH, Blackmon SH, Correa AM, Roth JA, Rice DC, Hofstetter W, Benjamin R, Mehran R, Swisher SG, Walsh GL, Vaporciyan AA. Progression after chemotherapy is a novel predictor of poor outcomes after pulmonary metastasectomy in sarcoma patients. J Am Coll Surg 212(5):821-6, 5/2011. e-Pub 3/23/2011. PMID: 21435923.
14. Hemmati SH, Correa AM, Walsh GL, Swisher SG, Roth JA, Rice DC, Mehran RJ, Vaporciyan AA. The prognostic factors of chest wall metastasis resection. Eur J Cardiothorac Surg. e-Pub 4/3/2011. PMID: 21466960.
15. Mehran R, Rice D, El-Zein R, Huang JL, Vaporciyan A, Goodyear A, Mehta A, Correa A, Walsh G, Roth J, Swisher S, Hofstetter W. Minimally invasive esophagectomy versus open esophagectomy, a symptom assessment study. Dis Esophagus 24(3):147-52, 4/2011. e-Pub 10/11/2010. PMID: 21040152.
16. Palacio D, Mehran RJ, Marom EM. Esophageal luminal clot mimicking intramural esophageal hematoma. Ann Thorac Surg 91(2):e29, 2/2011. PMID: 21256262.
17. Gaur P, Sepesi B, Hofstetter WL, Correa AM, Bhutani MS, Watson TJ, Swisher SG, M. D. Anderson Esophageal Cancer Group, University of Rochester School of Medicine and Dentistry Foregut Group. Endoscopic esophageal tumor length: a prognostic factor for patients with esophageal cancer. Cancer 117(1):63-9, 1/1/2011. e-Pub 8/27/2010. PMID: 20803613.
18. Hayashi Y, Correa AM, Hofstetter WL, Vaporciyan AA, Rice DC, Walsh GL, Mehran RJ, Lee JH, Bhutani MS, Dekovich A, Swisher SG, Ajani JA. The influence of high body mass index on the prognosis of patients with esophageal cancer after surgery as primary therapy. Cancer 116(24). e-Pub 11/2010. PMID: 21061356.
19. Casal RF, Jimenez CA, Mehran RJ, Eapen GA, Ost D, Sarkiss M, Morice RC. Infected mediastinal bronchogenic cyst successfully treated by endobronchial ultrasound-guided fine-needle aspiration. Ann Thorac Surg 90(4):e52-3, 10/2010. PMID: 20868780.
20. Swisher SG, Hofstetter W, Komaki R, Correa AM, Erasmus J, Lee JH, Liao Z, Maru D, Mehran R, Patel S, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Ajani JA. Improved long-term outcome with chemoradiotherapy strategies in esophageal cancer. Ann Thorac Surg 90(3):892-8; discussion 898-9, 9/2010. PMID: 20732514.
21. Kim MP, Correa AM, Lee J, Rice DC, Roth JA, Mehran RJ, Walsh GL, Ajani JA, Maru DM, Chang JY, Marom EM, Macapinlac HA, Lee JH, Vaporciyan AA, Rice T, Swisher SG, Hofstetter WL. Pathologic T0N1 esophageal cancer after neoadjuvant therapy and surgery: an orphan status. Ann Thorac Surg 90(3):884-90; discussion 890-1, 9/2010. PMID: 20732513.
22. Katz RL, He W, Khanna A, Fernandez RL, Zaidi TM, Krebs M, Caraway NP, Zhang HZ, Jiang F, Spitz MR, Blowers DP, Jimenez CA, Mehran RJ, Swisher SG, Roth JA, Morris JS, Etzel CJ, El-Zein R. Genetically abnormal circulating cells in lung cancer patients: an antigen-independent fluorescence in situ hybridization-based case-control study. Clin Cancer Res 16(15):3976-87, 8/1/2010. e-Pub 7/22/2010. PMCID: PMC2949278.
23. Kim MP, Correa AM, Swisher SG, Hofstetter WL, Mehran RJ, Rice DC, Walsh GL, Erasmus J, Moran C, Vaporciyan AA, Roth JA. Non-small cell lung cancer resection in lymphoma patients. Ann Thorac Surg 90(1):210-6, 7/2010. PMID: 20609777.
24. Gaur P, Hofstetter WL, Bekele BN, Correa AM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Rice TW, Swisher SG. Comparison between established and the Worldwide Esophageal Cancer Collaboration staging systems. Ann Thorac Surg 89(6):1797-1803, 1804.e1-3; discussion 1803-4, 6/2010. PMID: 20494031.
25. Behrens C, Feng L, Kadara H, Kim HJ, Lee JJ, Mehran R, Hong WK, Lotan R, Wistuba II. Expression of interleukin-1 receptor-associated kinase-1 in non-small cell lung carcinoma and preneoplastic lesions. Clin Cancer Res 16(1):34-44, 1/1/2010. e-Pub 12/22/2009. PMCID: PMC2811365.
26. Morice RC, Jimenez CA, Eapen GA, Mehran RJ, Keus L, Ost D. Using quantitative breath sound measurements to predict lung function following resection. J Cardiothorac Surg 5:81, 2010. e-Pub 10/12/2010. PMCID: PMC2964689.
27. Braiteh F, Correa AM, Hofstetter WL, Rice DC, Vaporciyan AA, Walsh GL, Roth JA, Mehran RJ, Swisher SG, Ajani JA. Association of age and survival in patients with gastroesophageal cancer undergoing surgery with or without preoperative therapy. Cancer 115(19):4450-8, 10/2009. e-Pub 6/2009. PMID: 19562780.
28. Bolton WD, Hofstetter WL, Francis AM, Correa AM, Ajani JA, Bhutani MS, Erasmus J, Komaki R, Maru DM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Swisher SG. Impact of tumor length on long-term survival of pT1 esophageal adenocarcinoma. J Thorac Cardiovasc Surg 138(4):831-6, 10/2009. e-Pub 4/2009. PMID: 19660349.
29. Raso MG, Behrens C, Herynk MH, Liu S, Prudkin L, Ozburn NC, Woods DM, Tang X, Mehran RJ, Moran C, Lee JJ, Wistuba II. Immunohistochemical expression of estrogen and progesterone receptors identifies a subset of NSCLCs and correlates with EGFR mutation. Clin Cancer Res 15(17):5359-68, 9/1/2009. e-Pub 8/25/2009. PMID: 19706809.
30. Blackmon SH, Shah N, Roth JA, Correa AM, Vaporciyan AA, Rice DC, Hofstetter W, Walsh GL, Benjamin R, Pollock R, Swisher SG, Mehran R|. Resection of pulmonary and extrapulmonary sarcomatous metastases is associated with long-term survival. Ann Thorac Surg 88(3):877-84; discussion 884-5, 9/2009. PMID: 19699915.

Invited Articles
1. Welsh J, Amini A, Likhacheva A, Erasmus J J, Gomez D, Davila M, Mehran RJ, Komaki R, Liao Z, Hofstetter WL, Lee H J, Bhutani MS, Ajani JA. Update: Modern Approaches to the Treatment of Localized Esophageal Cancer. Curr Oncol Rep. e-Pub 3/2011. PMID: 21365188.
2. Mehran RJ. Video-assisted thoracic surgery (VATS). Chest 127:1872, 2005.

Abstracts
1. Kim JY, Correa AM, Swisher SG, Rice DC, Walsh GL, Vaporciyan AA, Mehran RJ, Roth JA, Bhutani M, Maru D, Welsh J, Ajani J, Rohren E, Hofstetter WL. Does the Timing of Esophagectomy after Neoadjuvant Chemoradiation Affect Outcome?. STS 47th Annual Meeting - Jan. 2011 (#17), 1/2011.

Book Chapters
1. Komaki R, Tsao A, Mehran R. Non-Small Cell Lung Cancer. In: 60 Years of Survival Outcomes at The University of Texas M. D. Anderson Cancer Center, Chapter 6. Ed(s) M. Alma Rodrigues, Ronald S. Walters, Thomas W. Burke. Springer: New York, 45-62, 2012.
2. Hematti H, Mehran RJ. Anatomy of the thoracic duct. In: Thorac Surg Clin. 21, 2. Ed(s) Doctor Jean Deslauriers. Elsevier, 229-238, 5/2011. ISBN: 21477773.
3. McAleer MR, Mehran RJ, Tsao A. Mesothelioma. In: Lung Cancer Prevention, Management, and Emerging Therapies. Ed(s) Stewart DJ. Humana Press, a part of Springer Science+Business Media: New York, NY, 435-465, 2011. ISBN: 978-1-60761-523-1.
4. Mehran R and Roth JA. Resection of pulmonary metastases (open/thorascopic). In: Atlas of Advanced Operative Surgery. Elsevier, Inc., 2010.

Books (edited and written)
1. Deslauriers J, Mehran R. Ed(s) Deslauriers J, Mehran R. Handbook of Perioperative Care in General Thoracic Surgery. Elsevier Mosby, Inc. Philadelphia, PA, 2005.

Last updated: 3/12/2013