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Richard E. Wendt, III, Ph.D.

Present Title & Affiliation

Primary Appointment

Professor, Department of Imaging Physics, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
Program Director, Medical Physics, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX

Bio Statement

Richard E. Wendt III studied physics and business administration at the University of Chicago where he earned the AB degree in 1976 and the MBA degree in 1977. He studied Electrical Engineering at Rice University where he earned the MS degree in 1980 and the PhD degree in 1982. His dissertation work was on the computerized image processing of nuclear medicine data. He worked in NMR imaging as a post-doctoral fellow in the Department of Radiology of Baylor College of Medicine and then joined its faculty in 1984. In 1996, he joined the faculty of the Department of Nuclear Medicine of The University of Texas M. D. Anderson Cancer Center and then moved to the Department of Imaging Physics when it was formed. He serves as the Director of the Graduate Program in Medical Physics of The University of Texas Graduate School of Biomedical Sciences at Houston and co-ordinates the program's core course in nuclear medicine and magnetic resonance imaging physics. He is the chairman of the Clinical Faculty Review Committee and vice-chairman of the Radiation Safety Committee at M. D. Anderson. He is a member of the Graduate Education Program Review Committee of the Commission on the Accreditation of Medical Physics Education Programs. He is currently the institutional PI on a subaward of an SBIR Phase II grant to a local biotech company that is developing a new therapeutic radiopharmaceutical and the PI of a study supported by a local foundation to study the radiation safety of beta-emitting radionuclides in veterinary patients.

Research Interests

  • Radiopharmaceutical internal dosimetry and beta-emitting brachytherapy
  • Analysis of dynamic and multispectral datasets

Clinical Interests

  • Radiation shielding of nuclear medicine facilities
  • Release of radioactive patients from radiation safety restrictions

Education & Training

Degree-Granting Education

1982 Rice University, Houston, TX, PHD, Electrical Engineering
1980 Rice University, Houston, TX, MS, Electrical Engineering
1977 University of Chicago, Chicago, IL, MBA, Business Administration
1976 University of Chicago, Chicago, IL, AB, Business Administration (also completed degree requirements in Physics and Mathematics)

Postgraduate Training

6/1982-5/1984 Postdoctoral Fellowship, NMR Imaging, Baylor College of Medicine, Houston, TX, R. Nick Bryan, M.D., Ph.D.

Board Certifications

6/1995 American Board of Science in Nuclear Medicine, with special competence in Nuclear Medicine Physics and Instrumentation, Recertification Date: 12/2013
4/1999 American Board of Medical Physics, with special competence in Magnetic Resonance Imaging Physics, Recertification Date: 9/2013

Selected Publications

Peer-Reviewed Original Research Articles

1. Zhou JJ, Gonzalez A, Lenox MW, Fossum TW, Frank RK, Simon J, Stearns S, Ruoff CM, Wendt III RE, Akabani G. Dosimetry of 90Y-Hydroxide Treatment of Canine Osteosarcoma Using PET/CT: A Liquid Brachytherapy Approach. Applied Radiation and Isotopes 97:193-200, 5/2015.
2. Wendt III, RE. Principal Component Analysis of EBT2 Radiochromic Film for Multichannel Film Dosimetry. International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 3(3):156-166,, 8/2014.
3. Simon J, Frank RK, Crump DK, Erwin WD, Ueno NT, Wendt RE. A Preclinical Investigation of the Saturation and Dosimetry of Sm-153-DOTMP as a Bone-Seeking Radiopharmaceutical. Nuclear Medicine and Biology 39(6):770-776, 8/2012. PMCID: PMCPMC3389123.
4. Nishii R, Tong W, Wendt R, Soqhomonyan S, Mykhopadhyay U, Balatoni J, Mawlawi O, Bidaut L, Tinkey P, Borne A, Alauddin M, Gonzalez-Lepera C, Yang B, Gelovani J. Pharmacokinetics, Metabolism, Biodistribution, Radiation Dosimetry and Toxicology of 18F-Fluoroacetate (18F-FACE) in Non-Human Primates. Molecular Imaging and Biology 14(2):213-224, 4/2012. e-Pub 5/2011. PMID: 21437735.
5. Tian M, Ogawa K, Wendt R, Mykhopadhyay U, Balatoni J, Fukumitsu N, Uthamanthil R, Borne A, Brammer D, Jackson J, Mawlawi O, Alauddin M, Gelovani J. Pharmacokinetics, Biodistribution, Metabolism and Radiation Dosimetry Estimates of 18F-PEG6-IPQA in Nonhuman Primates. Journal of Nuclear Medicine 52(6):934-941, 6/2011. PMCID: PMCPMC4013275.
6. Dickinson RL, Erwin WD, Stevens DM, Bidaut LM, Mar MV, Macapinlac HA, Wendt III RE. Hybrid Modality Fusion of Planar Scintigrams and CT Topograms to Localize Sentinel Lymph Nodes in Breast Lymphoscintigraphy: Technical Description and Phantom Studies. International Journal of Molecular Imaging 2011, Article ID 298102,, 12/2010.
7. Nunez R, Erwin WD, Wendt III RE, Stachowiak A, Mar M, Stevens D, Madewell JE, Yeung HW, Macapinlac HA. Acquisition Parameters for Oncologic Imaging with a New SPECT/Multislide CT Scanner. Molecular Imaging and Biology 12(2):110-138, 2/2010. PMID: 20049543.
8. Ueno NT, de Souza JA, Booser D, Nakayama K, Madewell J, Wendt RE III, Hortobagyi GN, Podoloff D, Champlin RE. Pilot Study of Targeted Skeletal Radiotherapy for Bone-Only Metastatic Breast Cancer. Clinical Breast Cancer 9(3):173-177, 8/2009. PMID: 19661041.
9. Mar MV, Dickinson RL, Erwin WD and Wendt RE. Optimal Co-57 Flood Source Activity and Acquisition Time for Lymphoscintigraphy Localization Images. Journal of Nuclear Medicine Technology 36(2):82-87, 6/2008. PMID: 18483139.
10. Christoforidou AV, Saliba RM, Williams P, Qazilbash M, Roden L, Aleman A, Weber D, Mendoza F, Podoloff D, Wendt R, Breitz H, Alexanian R, Champlin R, Giralt S. Results of a retrospective single institution analysis of targeted skeletal radiotherapy with (166)Holmium-DOTMP as conditioning regimen for autologous stem cell transplant for patients with multiple myeloma. Impact on transplant outcomes. Biology of Blood Marrow and Transplantation 13(5):543-9, 5/2007. e-Pub 2/2007. PMID: 17448913.
11. Madsen MT, Anderson JA, Halama JR, Kleck J, Simpkin DJ, Votaw JR, Wendt RE, Williams LE and Yester MV. AAPM Task Group 108: PET and PET/CT Shielding Requirements. Medical Physics 33(1):4-15, 2006. PMID: 16485403.
12. Breitz HB, Wendt RE, Stabin MS, Shen S, Erwin WD, Rajendran JG, Eary JF, Durack L, Delpassand E, Martin W and Meredith RF. Ho-166-DOTMP Radiation Absorbed Dose Estimation for Skeletal Targeted Radiotherapy (STR). Journal of Nuclear Medicine 47(3):534-542, 2006. PMID: 16513624.
13. Kappadath SC, Erwin WD and Wendt RE. Observed Inter-Camera Variability of Clinically Relevant Performance Characteristics for Siemens Symbia Gamma Cameras. Journal of Applied Clinical Medical Physics 7(4):74-80, 2006. PMID: 17533358.
14. Bandi V, Velamuri S, Sirgi C, Wendt J, Wendt R, Guntupalli K. Deposition Pattern of Heliox-Driven Bronchodilator Aerosol in the Airways of Stable Asthmatics. Journal of Asthma 42(7):583-6, 9/2005. PMID: 16169793.
15. Schechter NR, Wendt RE, Yang DJ, Azhdarinia A, Erwin WD, Stachowiak AM, Broemeling LD, Kim EE, Cox JD, Podoloff DA and Ang KK. Radiation Dosimetry of Tc-99m Labeled C225 in Patients with Squamous Cell Carcinoma of the Head and Neck. Journal of Nuclear Medicine 45:1683-1687, 10/2004. PMID: 15471833.
16. Wen X, Cao X, Pasuelo MJ, Wendt R and Li C. Polymeric Radiotracers in Nuclear Imaging. Current Drug Delivery 1(4):377-384, 2004. PMID: 16305399.
17. Keleher A, Wendt R, Delpassand E, Stachowiak A and Kuerer H. The Safety of Lymphatic Mapping in Pregnant Breast Cancer Patients Using Tc-99m Sulfur Colloid. The Breast Journal 10(6):492-495, 2004. PMID: 15569204.
18. Breitz H, Wendt R, Stabin M, Bouchet L and Wessels B. Dosimetry of High Dose Skeletal Targeted Radiotherapy (STR) with Ho-166-DOTMP. Cancer Biotherapy & Radiopharmaceuticals 18(2):225-230, 2003. PMID: 12804048.
19. Giralt S, Bensinger W, Goodman M, Podoloff D, Eary J, Wendt R, Alexanian R, Weber D, Maloney D, Holmberg L, Rajandran J, Breitz H, Ghalie R and Champlin R. Ho-166-DOTMP Plus Melphalan Followed by Peripheral Blood Stem Cell Transplantation in Patients with Multiple Myeloma. Blood 102(7):2684-2691, 2003. PMID: 12730103.
20. Anderson RH, Devine WA, Uemura H, Geva T, Vick III GW, Wendt RE, Rokey R. Diagnosis of Heterotaxy Syndrome [2]. Circulation 91(3):906-908, 3/1995. PMID: 7828322.

Last updated: 5/13/2015