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Robert L Satcher, Jr, M.D., Ph.D

Present Title & Affiliation

Primary Appointment

Assistant Professor, Orthopaedic Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Adjunct Professor, Ken Kennedy Institute of Information Technology, Rice University, Houston, TX

Office Address

The University of Texas MD Anderson Cancer Center
1400 Pressler Street
Unit Number: 1448
Houston, TX 77030
Room Number: FCT10.5044
Phone: 713-794-5242
Fax: 713-792-8448

Education & Training

Degree-Granting Education

1994 Harvard Medical School, Boston, MA, MD, Medicine
1993 Massachusetts Institute of Technology, Boston, MA, PHD, Chemical Engineering
1986 Massachusetts Institute of Technology, Cambridge, MA, SB, Chemical Engineering

Postgraduate Training

2008-2010 Extravehicular Activity Training, Neutral Buoyancy Laboratory, NASA - Johnson Space Center, Houston, TX
2008 Robotic Arm Training Fellowship, Japanese Space Agency, JAXA, Tskuba, Japan
2004-2006 Astronaut Candidate Basic Training, NASA - Johnson Space Center, Houston, TX
2000-2001 Clinical Fellowship, Orthopaedic Oncology Surgery Clinical, Enneking Fellow, University of Florida - Shands Hospital Center, Gainesville, FL
1997-2000 Research Fellowship, Bone Biology and Endocrinology Laboratory, UCSF, San Francisco, CA
1997-1998 Research Fellowship, Bone Biology and Cellular Biomechanics, University of California - Berkeley and UCSF, Berkeley, CA
1995-2000 Clinical Residency, Orthopaedic Surgery Resident, University of California, San Francisco, CA
1994-1995 General Surgery Internship, Intern, University of California, San Francisco, CA
1993-1994 Research Fellowship, Vascular Pathology and Fluid Dynamics, Harvard Medical School, MA and MIT, Cambridge, MA
1993 Clinical Fellowship, Surgery and Internal Medicine, Schweitzer Fellow, Albert Schweitzer Hospital, Lambarane, Gabon
1984-1985 Engineer Internship, Polymer Chemistry, DuPont Internship, El DuPont deNemours & Co, Camden, SC
1982-1983 Engineer Internship, Rheological Studies of Polymer Melts, Polymer Products Division, DuPont Internship, El DuPont deNemours & Co, Camden, SC

Board Certifications

2013 American Board of Orthopaedic Surgery
2013 American Board of Orthopaedic Surgery
1995 National Board of Medical Examiners

Experience/Service

Academic Appointments

Clinical Assistant Professor, Orthopaedic Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2007-10/2011
NASA Mission Specialist Astronaut, NASA - Johnson Space Center, Houston, TX, 2004-2011
Adjunct Professor, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 2004
Assistant Professor, Biomedical Engineering, Northwestern University, Evanston, IL, 2002-2008
Attending Physician, Orthopaedic Oncology, Northwestern Memorial Hospital - Robert H. Lurie Comprehensive Cancer Center, Chicago, IL, 2001-7/2008
Assistant Professor, Orthopaedic Surgery, Northwestern University, The Feinberg School of Medicine, Chicago, IL, 2001-2008
Assistant Professor, Orthopaedic Surgery, Children's Memorial Hospital, Chicago, IL, 2001-2008
Adjunct Professor, Institute for Bionanotechnology in Medicine, Northwestern University Medical Center, Chicago, IL, 2001-2008

Other Appointments/Responsibilities

Member, Institute of Medicine, Committee to Review NASA's Evidence Reports on Health Risk, Washington, DC, 2013-present
User Panel Member, National Space Biomedical Research Institute, Houston, TX, 2013-present
Board Member, CSTEM (Communication, Science, Technology, Engineering, and Mathematics, Houston, TX, 1/2012
Board Member, Teach For America, Houston, TX, 1/2012
Board Member, ConvergeUS, Washington, DC, 1/2012
Vice Chairman, Board of Trustees, Voorhees College, Denmark, SC, 2011-present
Faculty Lead, Cancer Center development projects in Ethiopia, Ghana and Nigeria, MD Anderson Cancer Center, Houston, TX, 2011-present
Faculty Lead, Telemedicine and Telesurgery on Cancer Care program development, MD Anderson Cancer Center, Houston, TX, 2011-present
Member, Science and Research Committee, JR Gladden Society, American Academy of Orthopaedic Surgeons, Rosemont, PA, 2009-present
Member, Visiting Committee of MIT Corporation, Whitaker College for Biomedical Sciences, Health Sciences and Technology, Cambridge, MA, 2008-present
Member, Biomedical Research Committee, American Academy of Orthopaedic Surgeons, Rosemont, PA, 2008-present
District IV Representative, National Selection Committee, Massachusetts Institute of Technology Alumni Association, Cambridge, MA, 2008-2011
Member, Council on Research, American Academy of Orthopaedic Surgeons, Rosemont, IL, 2008
Member, Bone Cancer Panel, National Comprehensive Cancer Network, Fort Washington, PA, 2004-present

Military or Other Governmental Service

Astronaut Representative, Musculoskeletal Injury Advisory Committee, NASA, Johnson Space Center, 2009-2010
Astronaut Representative, Committee for the Protection of Human Subjects, NASA, Johnson Space Center, 2007-present
Appointed Member, Human Medical Research Board, NASA, Johnson Space Center, 2006-present
Mission Specialist, Astronaut, NASA, Johnson Space Center,, 2004-2011

Institutional Committee Activities

Member, Division of Surgery Educational Initiatives Committee, 2012-present
Africa Committee, Global Academic Programs and Business Development, 2011-present
Chairman, Telemedicine and Telesurgery for Regional Care Centers, 2011-present

Honors and Awards

2013 1st Annual Strong Mean & Women in Virginia History, Library of Virginia and Dominion
2013 Business/Civic Leadership Forum Fellow, Center for Houston's Future
2012 Dunn Foundation Collaborative Research Award, John S. Dunn Foundation
2012 Honorary Doctorate of Science, St. Paul's College
2012 Honorary Doctorate of Science, Voorhees College
2010 Finalist, Tuskegee University Presidency Search
2009 American-British-Canadian (ABC) Fellow, American Orthopaedic Association (AOA)
2009 Mission Specialist Astronaut, STS - 129/ULF3 Space Shuttle Atlantis Mission
2008 Leadership Fellows Program, Class of 2008-2009, AAOS
2008 Selected for "America's Top Surgeons", Consumers' Research Council of America
2008 Selected for Who's Who, Black Houston
2004 Crain's 40 under 40 Laureate, Crain's Business Journal, Chicago, IL
2002-2003 Career Development Award, Orthopaedic Research and Education Foundation
1997 Merck - UNCF Scholar, Merck - UNCF Postdoctoral Fellowship, Merck, Inc.
1991 Best Research Award for "The Distribution of fluid forces on arterial endothelial cells", American Society of Mechanical Engineers
1986 Albert G. Hill Award, Dean of Engineering Award, Massachusetts Institute of Technology
1985 Monsanto Award, Dean of Engineering Award for highest GPA, Massachusetts Institute of Technology
1985 Tau Beta Pi Engineering Honor Society, Massachusetts Institute of Technology
1984 National Merit Scholar, Summer Education Enrichment Program Scholar, Medical College of Georgia
1982-1986 Scholastic Collegiate Scholarships, DuPont de Nemours Inc.
1982 Valedictorian, Denmark-Olar High School

Professional Memberships

American Academy of Cancer Research
Member, 2004-present
American Academy of Orthopaedic Surgeons
Member, 2001-present
American Institute of Chemical Engineering
Member, 1994-present
American Physical Society
Member, 1993-present
American Telemedicine Association
Member, 2011-present
Association of Space Explorers
Member, 2010-present
Black Alumni of MIT (BAMIT): Board
Vice Chairman, 2002-2004
Black Graduate Student's Association at MIT
Co-chairman, 1991-1992
Connective Tissue Oncology Society
Member, 2004-present
eHealth Research Institute, Houston, TX
Co-Chair, 2013
Giant Cell Tumor of Bone NCCN Guideline Version, Philadelphia, PA
Subcommittee member, 9/2012
Harvard Medical School Minority Faculty Development Program-submitted proposal leading to establishment of permanent office
Member, 1993
Harvard Medical School, Black Health Organization - 3rd Annual Black Alumni Weekend
Co-Chairperson, 1994
Harvard Medical School, Third World Caucus planning committee for Third World Weekend
Planning Committee, 1992
Institute of Medicine, Washington, DC
Member, 2013-present
Musculoskeletal Tumor Society
Member, 2002-present
National Comprehensive Cancer Network
Member, 2003-present
National Medical Association
Member, 1995-present
National Organization for the Professional Advancement of Blacks in Chemistry and Chemical Engineering
Member, 1998-present
National Selection Committee for MIT Corporation
Committee Member, 2008-2011
National Society of Black Engineers
Member, 1998
Orthopaedic Research Society
Member, 2002-present
Orthopaedics Overseas
Member, 1997-present
Project ECHO, NM
Member, 2013
Sigma Xi Scientific Research Society
Member, 1993-present
Society of Black Academic Surgeons
Member, 2000-present
Teach for American - Houston, Houston, TX
Member, 2013-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Satcher RL, Bogler O, Hyle L, Lee A, Simmons A, Williams R, Hawke E, Matin S, Brewster A,. Telemedicine and Telesurgery in Cancer Care: Inaugural Conference at MD Anderson Cancer Center. Journal of Surgical Oncology, 5/2014.
2. Satcher RL, Pan T, Cheng C, Lee Y, Lin S, Yu G, Li X, Hoang A, Tamboli P, Jonasch E, Gallick G, Lin S. Cadherin-11 in Renal Cell Carcinoma Bone Metastasis. PLOS ONE 9(2), http://www.plosone.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjournal.pone.0089880&representation=PDF. e-Pub 2/2014.
3. Satcher RL, Lin PP, Huran N, Fen L, Moon BS, Lewis VO. The benefit of surgical management of colorectal carcinoma bone metastases. Journal of Solid Tumors 3(6):27-37, 12/2013. e-Pub 12/2013.
4. Satcher RL. How Intraoperative Navigation is Changing Musculoskeletal Tumor Surgery. Orthopedic Clinics of North America 44(4):645-656, 10/2013.
5. Lee YC, Bilen MA, Yu G, Lin SC, Huang CF, Ortiz A, Cho H, Song JH, Satcher RL, Kuang J, Gallick GE, Yu-Lee LY, Huang W, Lin SH. Inhibition of Cell Adhesion by an Anti-cadherin 11 Antibody Prevents Bone Metastasis. Mol Cancer Res. e-Pub 8/2/2013. PMID: 23913163.
6. Biermann JS, Adkins DR, Agulnik M, Benjamin RS, Brigman B, Butrynski JE, Cheong D, Chow W, Curry WT, Frassica DA, Frassica FJ, Hande KR, Hornicek FJ, Jones RL, Mayerson J, McGarry SV, McGrath B, Morris CD, O'Donnell RJ, Randall RL, Santana VM, Satcher RL, Siegel HJ, von Mehren M, Bergman MA, Sundar H. Bone cancer. J Natl Compr Canc Netw 11(6):688-723, 6/1/2013. PMID: 23744868.
7. Xing Z, Moon BS, Satcher RL, Lin PP, Lewis VO. A long femoral stem is not always required in hip arthroplasty for patients with proximal femur metastases. Clin Orthop Relat Res 471(5):1622-7, 5/2013. e-Pub 1/30/2013. PMCID: PMC3613523.
8. Satcher RL, Bamidele O, Lin PP, Moon M, Hernandez M, Lewis VO, Chilton J. Racial disparities in survival outcomes of prostate cancer patients after surgery for bone metastases. Journal of Cancer Therapy:27-36, 4/2013.
9. Satcher RL, Lin P, Harun N, Feng L, Moon BS, Lewis VO. Surgical management of appendicular skeletal metastases in thyroid carcinoma. Int J Surg Oncol 2012:417086, 2012. e-Pub 12/12/2012. PMCID: PMC3530792.
10. Lee YC, Cheng CJ, Bilen MA, Lu JF, Satcher RL, Yu-Lee LY, Gallick GE, Maity SN, Lin SH. BMP4 promotes prostate tumor growth in bone through osteogenesis. Cancer Res 71(15):5194-203, 8/1/2011. e-Pub 6/13/2011. PMCID: PMC3148283.
11. Moon B, Lin P, Satcher R, Lewis V. Simultaneous nailing of skeletal metastases: is the mortality really that high? Clin Orthop Relat Res 469(8):2367-70, 8/2011. e-Pub 2/17/2011. PMCID: PMC3126951.
12. Kai L, Wang J, Ivanovic M, Chung YT, Laskin WB, Schulze-Hoepfner F, Mirochnik Y, Satcher RL, Levenson AS. Targeting prostate cancer angiogenesis through metastasis-associated protein 1 (MTA1). Prostate 71(3):268-80, 2/15/2011. e-Pub 8/17/2010. PMID: 20717904.
13. Mata A, Geng Y, Henrikson KJ, Aparicio C, Stock SR, Satcher RL, Stupp SI. Bone regeneration mediated by biomimetic mineralization of a nanofiber matrix. Biomaterials 31(23):6004-12, 8/2010. e-Pub 5/15/2010. PMCID: PMC2911435.
14. Biermann JS, Adkins DR, Benjamin RS, Brigman B, Chow W, Conrad EU, Frassica DA, Frassica FJ, George S, Hande KR, Hornicek FJ, Letson GD, Mayerson J, McGarry SV, McGrath B, Morris CD, O'Donnell RJ, Randall RL, Santana VM, Satcher RL, Siegel HJ, Somaiah N, Yasko AW, National Comprehensive Cancer Network Bone Cancer Panel. Bone cancer. J Natl Compr Canc Netw 8(6):688-712, 6/2010. PMID: 20581300.
15. Satcher R. An orthopaedic surgeon in space: an interview with Robert Satcher, MD, PhD. Interview by Tony Peregrin. Bull Am Coll Surg 95(4):11-5, 4/2010. PMID: 21456425.
16. Zhang S, Wang J, Bilen MA, Lin SH, Stupp SI, Satcher RL. Modulation of prostate cancer cell gene expression by cell-to-cell contact with bone marrow stromal cells or osteoblasts. Clin Exp Metastasis 26(8):993-1004, 2009. e-Pub 9/29/2009. PMID: 19787436.
17. Sargeant TD, Guler MO, Oppenheimer SM, Mata A, Satcher RL, Dunand DC, Stupp SI. Hybrid bone implants: self-assembly of peptide amphiphile nanofibers within porous titanium. Biomaterials 29(2):161-71, 1/2008. e-Pub 10/23/2007. PMID: 17936353.
18. Biermann JS, Adkins D, Benjamin R, Brigman B, Chow W, Conrad EU, Frassica D, Frassica FJ, George S, Healey JH, Heck R, Letson GD, Mayerson J, McGarry SV, O'Donnell RJ, Patt J, Randall RL, Santana V, Satcher RL, Schmidt RG, Siegel HJ, Wong MK, Yasko AW, National Comprehensive Cancer Network. Bone cancer. J Natl Compr Canc Netw 5(4):420-37, 4/2007. PMID: 17442233.
19. Wang J, Jarrett J, Huang CC, Satcher RL, Levenson AS. Identification of estrogen-responsive genes involved in breast cancer metastases to the bone. Clin Exp Metastasis 24(6):411-22, 2007. e-Pub 6/26/2007. PMID: 17593529.
20. Wang J, Levenson AS, Satcher RL. Identification of a unique set of genes altered during cell-cell contact in an in vitro model of prostate cancer bone metastasis. Int J Mol Med 17(5):849-56, 5/2006. PMID: 16596270.
21. Levenson AS, Thurn KE, Simons LA, Veliceasa D, Jarrett J, Osipo C, Jordan VC, Volpert OV, Satcher RL, Gartenhaus RB. MCT-1 oncogene contributes to increased in vivo tumorigenicity of MCF7 cells by promotion of angiogenesis and inhibition of apoptosis. Cancer Res 65(23):10651-6, 12/1/2005. PMID: 16322206.
22. Patton KT, Satcher RL, Laskin WB. Capillary hemangioblastoma of soft tissue: report of a case and review of the literature. Hum Pathol 36(10):1135-9, 10/2005. e-Pub 9/8/2005. PMID: 16226115.
23. Biermann JS, Baker LH, Benjamin R, Brigman B, Chow W, Conrad EU, Frassica D, Frassica FJ, George S, Healey JH, Heck R, Letson GD, Mayerson J, Neff J, O'Donnell RJ, Randall RL, Santana V, Satcher RL, Schmidt RG, Siegel HJ, Wong MK, Yasko AW, National Comprehensive Cancer Network. Bone cancer clinical practice guidelines. J Natl Compr Canc Netw 3(2):124-40, 3/2005. PMID: 19817025.
24. Levenson AS, Thurn TE, Veliceasa D, Jerrett J, Osipo C, Jordan V, Volpert Ov, Satcher RL, Gartenhaus RB. Overexpression of MCTA oncogene contributes to increased tumurogenicity of MCF7 breast cancer cells. Cancer Research 65(23):10651 - 6, 2005.
25. Satcher RL, Dvorkin K, Levenson AS, Vandenbroek T, Stupp SI. Gene expression in cancer cells is influenced by contact with bone cells in a novel coculture system that models bone metastasis. Clin Orthop Relat Res(426):54-63, 9/2004. PMID: 15346052.
26. Garcia ND, Morasch MD, Sam AD, Satcher RL, Blum MG, Fullerton DA. Inferior vena cava thrombus removal using hypothermic circulatory arrest in two patients with osteosarcoma. Ann Vasc Surg 17(6):686-9, 11/2003. PMID: 14738095.
27. Satcher RL, Noss RS, Yingling CD, Ressler J, Ries M. The use of motor-evoked potentials to monitor sciatic nerve status during revision total hip arthroplasty. J Arthroplasty 18(3):329-32, 4/2003. PMID: 12728425.
28. Satcher RL, Levenson AS, Dvorkin K, Stupp SI. Quantifying the role of cell-cell contact for establishing bone metastasis using a novel co-culture system. Proceeding of the American Association for Cancer Research 44(55), 2003.
29. Satcher, RL, O'Donnell R, Johnston JO. Reconstruction of the pelvis following resection of malignant tumors about the acetabulum. Clinical Orthopaedics and Related Research 1(408), 2003.
30. Nauman EA, Satcher RL, Keaveny TM, Halloran BP, Bikle DD. Osteoblasts respond to pulsatile fluid flow with short-term increases in PGE(2) but no change in mineralization. J Appl Physiol 90(5):1849-54, 5/2001. PMID: 11299276.
31. Allred DR, Carlton JM, Satcher RL, Long JA, Brown WC, Patterson PE, O'Connor RM, Stroup SE. The ves multigene family of B. bovis encodes components of rapid antigenic variation at the infected erythrocyte surface. Mol Cell 5(1):153-62, 1/2000. PMID: 10678177.
32. Satcher RL. African Americans and orthopaedic surgery. A resident's perspective. Clin Orthop Relat Res(362):114-6, 5/1999. PMID: 10335289.
33. Nauman EA, Risic KJ, Keaveny TM, Satcher RL. Quantitative assessment of steady and pulsatile flow fields in a parallel plate flow chamber. Ann Biomed Eng 27(2):194-9, Mar-Apr, 3/1999. PMID: 10199696.
34. Nauman EA, Chang WCW, Satcher RL, Keaveny TM. Microscale Engineering applications in bone adaption. Microscale Thermophysical Engineering 2:139-172, 1998.
35. Satcher R, Dewey CF, Hartwig JH. Mechanical remodeling of the endothelial surface and actin cytoskeleton induced by fluid flow. Microcirculation 4(4):439-53, 12/1997. PMID: 9431512.
36. Satcher RL, Dewey CF. Theoretical estimates of mechanical properties of the endothelial cell cytoskeleton. Biophys J 71(1):109-18, 7/1996. PMCID: PMC1233462.
37. Satcher RL, Dewey CF. Mechanical properties of actin cytoskeleton of endothelial cells. Annals of Biomedical Engineering 23(Supplement 1):s-26, 1995.
38. Laurencin CT, Gerhart T, Witschger P, Satcher R, Domb A, Rosenberg AE, Hanff P, Edsberg L, Hayes W, Langer R. Bioerodible polyanhydrides for antibiotic drug delivery: in vivo osteomyelitis treatment in a rat model system. J Orthop Res 11(2):256-62, 3/1993. PMID: 8483038.
39. Satcher RL, Bussolari SR, Gimbrone MA, Dewey CF. The distribution of fluid forces on model arterial endothelium using computational fluid dynamics. J Biomech Eng 114(3):309-16, 8/1992. PMID: 1522724.
 

Other

1. Thesis. Satcher RL PhD Thesis: A Mechanical Model of Vascular Endothelium, Massachusetts Institute of Technology, 1993.

Grant & Contract Support

Funding Source: John S. Dunn Foundation Collaborative Research Award
Role: Principal Investigator
Duration: 2012 - present
 
Funding Source: ATT Telesurgery Grant
Role: Co-Investigator
Duration: 2011 - 2014
 
Title: Robert Wood Johnson Foundation
Funding Source: Robert Wood Johnson Foundation
Role: Principal Investigator
Duration: 3/2008 - 3/2011
 
Title: Nanotechnology Strategies for growth of bones and teeth
Funding Source: NIH/NCI
Role: Co-Investigator
Duration: 7/12/2005 - 6/30/2010
 
Title: SPORE in prostate cancer
Funding Source: NIH/NCI
Role: Co-Investigator
Duration: 5/1/2004 - 4/30/2006
 
Title: Robert Wood Johnson Foundation
Funding Source: Robert Wood Johnson Foundation
Role: Principal Investigator
Duration: 12/2003 - 12/2005
 
Title: Estrogen and selective receptor modulators (SERMS) in breast cancer metastases to bone
Funding Source: Avon Foundation
Role: Co-Investigator
Duration: 3/1/2003 - 5/31/2004
 
Title: The use of mechanical forces to influence stem cell growth and development for the production of bone substitutes
Funding Source: Orthopedic Research and Education Foundation, Zimmer Career Development Award
Role: Principal Investigator
Duration: 7/1/2002 - 6/29/2003
 
Title: Role of cell contact in prostate skeletal metastasis
Funding Source: Robert H. Lurie Comprehensive Cancer Center, SPORE in prostate cancer
Role: Principal Investigator
Duration: 5/1/2002 - 4/30/2003
 
Title: Stem cell growth and Differentiation is influenced by mechanical forces
Funding Source: Children's Research Foundation, Children's Memorial Hospital
Role: Principal Investigator
Duration: 12/2/2001 - 11/30/2002
 
Funding Source: Merck/UNCF Biomedical Foundation
Role: Principal Investigator
Duration: 8/1997 - 8/1999
 
Title: In Vivo study of the use of antibiotic loaded biodegradable matrices in the treatment of osteomyelitis
Funding Source: MIT Undergraduate Research Grant
Role: Co-Investigator
Duration: 1985
 
Title: Cancer Survivorship Research Seed Money Grant
Funding Source: MD Anderson Cancer Center
Role: Principal Investigator
 
Title: R. Lee Clark Fellowship Grant Proposal
Funding Source: The University of Texas M.D. Anderson Cancer Center
Role: Principal Investigator-MDACC
 
Title: The Progression of Metastatic Renal Cell Carcinoma in Bone
Funding Source: UTMDACC Institutional Research Grant
Role: Principal Investigator

Last updated: 7/21/2014