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Sattva S. Neelapu, M.D.

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Lymphoma/Myeloma, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

1991 Jawaharlal Institute of Post-Graduate Medical Education and Research, Pondicherry, India, MBBS, Medicine

Postgraduate Training

7/2001-3/2004 Postdoctoral Fellowship, Tumor Immunology, National Cancer Institute, National Institutes of Health, Bethesda, MD
7/1998-6/2001 Clinical Fellowship, Medical Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD
7/1993-6/1995 Clinical Residency, Internal Medicine, Coney Island Hospital, Brooklyn, NY
7/1992-6/1993 Clinical Internship, Internal Medicine, Coney Island Hospital, Brooklyn, NY

Board Certifications

2000 American Board of Internal Medicine, Medical Oncology
1995 American Board of Internal Medicine, Internal Medicine

Honors and Awards

2008 Clinical Scientist Development Award, Doris Duke Charitable Foundation
2007 ASH Scholar Award, American Society of Hematology
2006 ASCO Career Development Award, American Society of Clinical Oncology
2003 AACR Scholar-in-Training Award, American Association for Cancer Research 94th Annual Meeting, Washington, D.C.
2003 ASCO Merit Award, American Society of Clinical Oncology 39th Annual Meeting, Chicago, IL
2002 Fellows Award for Research Excellence, National Cancer Institute, National Institutes of Health, Bethesda, MD
2001 Senior Fellowship Training Award, National Cancer Institute, National Institutes of Health, Bethesda, MD
1995 Virginia Nash Award for outstanding professional performance as a Resident on the Medical Services, Coney Island Hospital, Brooklyn, NY
1993 Dr. Ghani Mohammad Memorial Award for outstanding professional performance as an Intern on the Medical Services, Coney Island Hospital, Brooklyn, NY

Selected Publications

Peer-Reviewed Original Research Articles
1. Weng J, Cha SC, Matsueda S, Alatrash G, Popescu MS, Yi Q, Molldrem JJ, Wang M, Neelapu SS, Kwak LW. Targeting human B-cell malignancies through Ig light chain specific cytotoxic T lymphocytes. Clin Cancer Res. e-Pub 8/2011. PMID: 21813633.
2. Schuster SJ, Neelapu SS, Gause BL, Janik JE, Muggia FM, Gockerman JP, Winter JN, Flowers CR, Nikcevich DA, Sotomayor EM, McGaughey DS, Jaffe ES, Chong EA, Reynolds CW, Berry DA, Santos CF, Popa MA, McCord AM, Kwak LW. Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma. J Clin Oncol 29(20):2787-94, 7/10/2011. e-Pub 5/31/2011. PMID: 21632504.
3. Jamshed S, Fowler DH, Neelapu SS, Dean RM, Steinberg SM, Odom J, Bryant K, Hakim F, Bishop MR. EPOCH-F: a novel salvage regimen for multiple myeloma prior to reduced-intensity allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant 46(5):676-81, 5/2011. e-Pub 7/26/2010. PMID: 20661232.
4. Park HJ, Qin H, Cha SC, Sharma R, Chung Y, Schluns KS, Neelapu SS, Overwijk WW, Hwu P, Kwak LW. Induction of TLR4-dependent CD8+ T cell immunity by murine ß-defensin2 fusion protein vaccines. Vaccine 29(18):3476-82, 4/2011. e-Pub 3/2011. PMID: 21382485.
5. Chung Y, Tanaka S, Chu F, Nurieva RI, Martinez GJ, Rawal S, Wang YH, Lim H, Reynolds JM, Zhou XH, Fan HM, Liu ZM, Neelapu SS, Dong C. Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Nat Med 17(8):983-8, 2011. e-Pub 7/2011. PMCID: PMC3151340.
6. Qin H, Cha SC, Neelapu SS, Liu C, Wang YH, Wei J, Qin XF, Liu YJ, Kwak LW. Generation of an immune microenvironment as a novel mechanism for myotoxins to potentiate genetic vaccines. Vaccine 28(50):7970-8, 11/2010. PMID: 20937320.
7. Qin H, Cha SC, Neelapu SS, Lou Y, Wei J, Liu YJ, Kwak LW. Vaccine site inflammation potentiates idiotype DNA vaccine-induced therapeutic T cell-, and not B cell-, dependent antilymphoma immunity. Blood 114(19):4142-9, 11/2009. e-Pub 9/2009. PMID: 19749091.
8. Kannan S, Neelapu SS. Vaccination strategies in follicular lymphoma. Curr Hematol Malig Rep 4(4):189-95, 10/2009. PMID: 20425407.
9. Freedman A, Neelapu SS, Nichols C, Robertson MJ, Djulbegovic B, Winter JN, Bender JF, Gold DP, Ghalie RG, Stewart ME, Esquibel V, Hamlin P. Placebo-controlled phase III trial of patient-specific immunotherapy with mitumprotimut-T and granulocyte-macrophage colony-stimulating factor after rituximab in patients with follicular lymphoma. J Clin Oncol 27(18):3036-43, 6/2009. e-Pub 5/2009. PMID: 19414675.
10. Park HJ, Neelapu SS. Developing idiotype vaccines for lymphoma: from preclinical studies to phase III clinical trials. Br J Haematol 142(2):179-91, 6/2008. e-Pub 4/2008. PMCID: PMC2744838.
11. Lee ST, Liu S, Radvanyi L, Sukhumalchandra P, Molldrem JJ, Wieder ED, Hwu P, Liu YJ, Kwak LW, Lizée G, Neelapu SS. A novel strategy for rapid and efficient isolation of human tumor-specific CD4(+) and CD8(+) T-cell clones. J Immunol Methods 331(1-2):13-26, 2/2008. e-Pub 10/2007. PMCID: PMC2265521.
12. Neelapu SS, Gause BL, Harvey L, Lee ST, Frye AR, Horton J, Robb RJ, Popescu MC, Kwak LW. A novel proteoliposomal vaccine induces antitumor immunity against follicular lymphoma. Blood 109(12):5160-3, 6/2007. e-Pub 3/2007. PMCID: PMC1941785.
13. Neelapu SS, Kwak LW, Kobrin CB, Reynolds CW, Janik JE, Dunleavy K, White T, Harvey L, Pennington R, Stetler-Stevenson M, Jaffe ES, Steinberg SM, Gress R, Hakim F, Wilson WH. Vaccine-induced tumor-specific immunity despite severe B-cell depletion in mantle cell lymphoma. Nat Med 11(9):986-91, 9/2005. e-Pub 8/2005. PMID: 16116429.
14. Neelapu SS, Munshi NC, Jagannath S, Watson TM, Pennington R, Reynolds C, Barlogie B, Kwak LW. Tumor antigen immunization of sibling stem cell transplant donors in multiple myeloma. Bone Marrow Transplant 36(4):315-23, 8/2005. PMID: 15968284.
15. Neelapu SS, Baskar S, Gause BL, Kobrin CB, Watson TM, Frye AR, Pennington R, Harvey L, Jaffe ES, Robb RJ, Popescu MC, Kwak LW. Human autologous tumor-specific T-cell responses induced by liposomal delivery of a lymphoma antigen. Clin Cancer Res 10(24):8309-17, 12/2004. PMID: 15623607.

Last updated: 9/22/2011