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Shao-Rui Chen, M.D.

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Anesthesiology and Perioperative Medicine, Division of Anesthesiology and Critical Care, The University of Texas MD Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

1982 Qingdao Medical College, Shandong, PR China, China, MD, Clinical Medicine


Academic Appointments

Senior Research Associate, Anesthesiology, Penn State University College of Medicine, Hershey, PA, 7/2004-2/2006
Research Associate, Anesthesiology, Penn State University, Hershey, PA, 7/2000-6/2004
Research Assistant, Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, NC, 7/1996-6/2000
Research Assistant, Department of Internal Medicine, Division of Internal Medicine, University of Human Physiology and Internal Medicine, Davis, CA, 9/1992-6/2000
Resident and Attending Physician, Department of Pediatrics Patient Care, Division of Pediatrics, Xintai People's Hospital, Shandong, Peoples Republic, China, 8/1982-6/1992

Selected Publications

Peer-Reviewed Original Research Articles

1. Jin XG, Chen SR, Cao XH, Li L, Pan HL. Nitric oxide inhibits nociceptive transmission by differentially regulating glutamate and glycine release to spinal dorsal horn neurons. J Biol Chem 286(38):33190-202, 9/23/2011. e-Pub 8/3/2011. PMCID: PMC3190946.
2. Cheng PW, Lu PJ, Chen SR, Ho WY, Cheng WH, Hong LZ, Yeh TC, Sun GC, Wang LL, Hsiao M, Tseng CJ. Central nicotinic acetylcholine receptor involved in Ca(2+) -calmodulin-endothelial nitric oxide synthase pathway modulated hypotensive effects. Br J Pharmacol 163(6):1203-13, 7/2011. PMCID: PMC3144534.
3. Zhou HY, Chen SR, Pan HL. Targeting N-methyl-D-aspartate receptors for treatment of neuropathic pain. Expert Rev Clin Pharmacol 4(3):379-388, 5/1/2011. PMCID: PMC3113704.
4. Chen SR, Chen H, Yuan WX, Pan HL. Increased Pre- and Postsynaptic {alpha}2-Adrenoceptor Activity in the Spinal Dorsal Horn in Painful Diabetic Neuropathy. J Pharmacol Exp Ther 337(1):285-92, 4/2011. e-Pub 1/19/2011. PMCID: PMC3063741.
5. Wang R, Zhong X, Meng X, Koop A, Tian X, Jones PP, Fruen BR, Wagenknecht T, Liu Z, Chen SR. Localization of the dantrolene-binding sequence near the FK506-binding protein-binding site in the three-dimensional structure of the ryanodine receptor. J Biol Chem 286(14):12202-12, 4/2011. e-Pub 1/2011. PMCID: PMC3069424.
6. Zhou HY, Chen SR, Chen H, Pan HL. Functional plasticity of group II metabotropic glutamate receptors in regulating spinal excitatory and inhibitory synaptic input in neuropathic pain. J Pharmacol Exp Ther 336(1):254-64, 1/2011. e-Pub 10/2010. PMCID: PMC3014296.

Grant & Contract Support

Title: Mechanisms of Neuroal Plasticity in Neuropathic Pain
Funding Source: NIH/NINDS
Role: Collaborator
Principal Investigator: Hui-Lin Pan
Duration: 6/2007 - 5/2011
Title: Synaptic Mechanisms Regulating Sympathetic Drive
Funding Source: NIH/NINDS
Role: Collaborator
Principal Investigator: Hui-Lin Pan
Duration: 6/2005 - 5/2009

Last updated: 8/24/2012