Skip to Content

'
Sharon H. Giordano, MD, MPH

Present Title & Affiliation

Primary Appointment

Associate Professor of Medicine and Internist (with tenure), Department of Breast Medical Oncology, Division of Cancer Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX

Education & Training

Degree-Granting Education

2004 The University of Texas School of Public Health, Houston, TX, MPH, Disease Control
1996 The Johns Hopkins University School of Medicine, Baltimore, MD, MD, Medicine
1991 Yale University, New Haven, CT, BS, Summa Cum Laude, Biology

Postgraduate Training

7/1999-6/2002 Clinical Fellowship, Medical Oncology, The University of Texas M. D. Anderson Cancer Center. Houston, Texas, Robert A. Wolff, Houston, TX, Robert A. Wolff, M.D.
7/1996-6/1999 Internship and Residency in Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, Lisa Bellini, M.D.

Board Certifications

2002 Medical Oncology
1999 Internal Medicine

Selected Publications

Peer-Reviewed Original Research Articles
1. Smith GL, Xu Y, Shih YCT, Giordano SH, Smith BD, Hunt KK, Strom EA, Perkins GH, Hortobagyi GN, Buchholz TA. Breast-conserving surgery in older patients with invasive breast cancer: current patterns of treatment across the United States. J Am Coll Surg. In Press.
2. Dawood S, Broglio KH, Buzdar AU, Hortobagyi GN, Giordano SH. Prognosis of women with stage IV breast cancer by HER2 status and trastuzumab treatment: An institutional based review. J Clin Oncol. In Press.
3. Smith GL, Shih YT, Xu Y, Giordano SH, Smith BD, Perkins GH, Tereffe W, Woodward WA, Buchholz TA. Racial disparities in the use of radiation therapy following breast conserving surgery: A national Medicare study. CANCER. In Press.
4. Rao G, Giordano SH, Liu J, McCutcheon IE. The association of breast cancer and meningioma in men and women. Neurosurgery 65(3):483-9; discussion 489, 9/2009. PMID: 19687693.
5. Elting LS, Cooksley CD, Bekele BN, Giordano SH, Shih YC, Lovell KK, Avritscher EB, Theriault R. Mammography capacity impact on screening rates and breast cancer stage at diagnosis. Am J Prev Med 37(2). e-Pub 6/12/2009. PMID: 19524392.
6. Jiralerspong S, Palla SL, Giordano SH, Meric-Bernstam F, Liedtke C, Barnett CM, Hsu L, Hung MC, Hortobagyi GN, Gonzalez-Angulo AM. Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer. J Clin Oncol 27(20). e-Pub 6/1/2009. PMID: 19487376.
7. Shen Y, Dong W, Feig BW, Ravdin P, Theriault RL, Giordano SH. Patterns of treatment for early stage breast cancers at the M. D. Anderson Cancer Center from 1997 to 2004. Cancer 115(10):2041-51, 5/15/2009. e-Pub 3/2009. PMCID: PMC2716402.
8. Srokowski TP, Fang S, Hortobagyi GN, Giordano SH. Impact of diabetes mellitus on complications and outcomes of adjuvant chemotherapy in older patients with breast cancer. J Clin Oncol 27(13). e-Pub 3/23/2009. PMCID: PMC2674004.
9. Shih YC, Xu Y, Cormier JN, Giordano S, Ridner SH, Buchholz TA, Perkins GH, Elting LS. Incidence, treatment costs, and complications of lymphedema after breast cancer among women of working age: A 2-year follow-up study. J Clin Oncol 27(12). e-Pub 3/16/2009. PMID: 19289624.
10. Raji MA, Tamborello LP, Kuo YF, Ju H, Freeman JL, Zhang DD, Giordano SH, Goodwin JS. Risk of subsequent dementia diagnoses does not vary by types of adjuvant chemotherapy in older women with breast cancer. Med Oncol. e-Pub 12/2008. PMID: 19067255.
11. Smith GL, Buchholz TA, Giordano SH, Garden AS, Woodward WA, Krumholz HM, Weber RS, Ang KK, Rosenthal DI. Cerebrovascular disease risk in older head and neck cancer patients after radiotherapy. J Clin Oncol 26(31):5119-25, 2008. e-Pub 8/2008. PMID: 18725647.
12. Srokowski TP, Fang S, Duan Z, Buchholz TA, Hortobagyi GN, Goodwin JS, Giordano SH. Completion of adjuvant radiation therapy among women with breast cancer. Cancer 13(1):494-502, 2008. PMID: 18442124.
13. Giordano SH, Kuo YF, Duan Z, Hortobagyi GN, Goodwin JS. Limits of observational data in determining outcomes from cancer therapy. Cancer 112(11):2456-2466, 2008. PMID: 18428196.
14. Badgwell BD, Giordano SH, Duan ZZ, Fang S, Bedrosian I, Kuerer HM, Singletary SE, Hunt KK, Hortobagyi GN, Babiera G. Mammography before diagnosis among women age 80 years and older with breast cancer. J Clin Oncol 26(15):2482-8, 2008. PMID: 18427152.
15. Elting LS, Lu C, Escalante CP, Giordano SH, Trent J, Cooksley C, Avritscher EBC, Shih YCT, Ensor J, Bekele BN, Gralla R, Talcott JA, Rolston K. Outcomes and cost of outpatient or inpatient management of 712 patients with febrile neutropenia. J Clin Oncol 26(4):606-11, 2008. PMID: 18235119.
16. Buchholz TA, Woodward WA, Duan Z, Fang S, Oh JL, Tereffe W, Strom EA, Perkins GH, Yu TK, Hunt KK, Meric-Bernstam F, Hortobagyi GN, Giordano SH. Radiation use and long-term survival in breast cancer patients with T1, T2 primary tumors and one to three positive axillary lymph nodes. Int J Radiat Oncol Biol Phys 71(4):1022-7, 2008. PMID: 18234447.
17. Smith GL, Smith BD, Giordano SH, Shih YCT, Woodward WA, Strom EA, Perkins GH, Tereffe W, Yu TK, Buchholz TA. Risk of hypothyroidism in older breast cancer patients treated with radiation. Cancer 112(6):1371-9, 2008. PMID: 18213620.
18. Wang FW, Uretsky BF, Freeman JL, Zhang D, Giordano SH, Goodwin JS. Survival advantage in medicare patients receiving drug-eluting stents compared with bare metal stents: real or artefactual? Catheter Cardiovasc Interv 71(5):644-5, 2008. PMID: 18360856.
19. Dawood S, Broglio K, Gonzalez-Angulo AM, Buzdar AU, Hortobagyi GN, Giordano SH. Trends in survival over the past two decades among white and black patients with newly diagnosed stage IV breast cancer. J Clin Oncol 26(30):4891-8, 2008. PMID: 18725649.
20. Dawood SS, Broglio K, Kau SW, Green M, Giordano S, Meric-Bernstam F, Buchholz T, Albarracin C, Yang W, Hortobagyi G, Gonzalez-Angulo A. Triple receptor-negative breast cancer: The effect of race on response to primary systemic treatment and survival outcomes. J Clin Oncol 27(2):220-6, 2008. e-Pub 12/2008. PMID: 19047281.
21. Giordano SH, Fang S, Duan Z, Kuo YF, Hortobagyi GN, Goodwin JS. Use of intravenous bisphosphonates in older women with breast cancer. Oncologist 13(5):494-502, 2008. PMID: 18515734.
22. Patt DA, Duan Z, Fang S, Hortobagyi GN, Giordano SH. Acute myeloid leukemia after adjuvant breast cancer therapy in older women: understanding risk. J Clin Oncol 25(25). e-Pub 7/2007. PMID: 17664457.
23. Pinder MC, Duan Z, Goodwin JS, Hortobagyi GN, Giordano SH. Congestive heart failure in older women treated with adjuvant anthracycline chemotherapy for breast cancer. J Clin Oncol 25(25):3808-15, 2007. e-Pub 7/2007. PMID: 17664460.
24. Wildiers H, Kunkler I, Biganzoli L, Fracheboud J, Vlastos G, Bernard C, Hurria A, Extermann M, Girre V, Brain E, Audisio R, Bartelink H, Barton M, Giordano S, Muss H, Aapro M. Management of breast cancer in elderly individuals: recommendations of the International Society of Geriatric Oncology. Lancet Oncol 8(12):1101-15, 2007. PMID: 18054880.
25. Hanrahan EO, Gonzalez-Angulo AM, Giordano SH, Rouzier R, Broglio K, Hortobagyi GN, Valero V. Overall survival and cause-specific mortality of patients with stage T1a,bN0M0 breast carcinoma. J Clin Oncol 25(31):4952-60, 2007. PMID: 17971593.
26. Luo R, Giordano SH, Zhang DD, Freeman J, Goodwin JS. The role of the surgeon in whether patients with lymph node-positive colon cancer see a medical oncologist. Cancer 109(5):975-82, 2007. PMCID: PMC1851914.
27. Gonzalez-Angulo AM, Hennessy BT, Broglio K, Meric-Bernstam F, Cristofanilli M, Giordano SH, Buchholz TA, Sahin A, Singletary SE, Buzdar AU, Hortobagyi GN. Trends for inflammatory breast cancer: is survival improving? Oncologist 12(8)(8):904-12, 2007. PMID: 17766649.
28. Hennessy BT, Giordano SH, Broglio K, Duan Z, Trent J, Buchholz T, Babiera G, Hortobagyi G, Valero V. Biphasic metaplastic sarcomatoid carcinoma of the breast. Ann Oncol 17(4):605-13, 2006. e-Pub 2/2006. PMID: 16469754.
29. Boughey JC, Bedrosian I, Meric-Bernstam F, Ross MI, Kuerer HM, Akins JS, Giordano SH, Babiera GV, Ames FC, Hunt KK. Comparative analysis of sentinel lymph node operation in male and female breast cancer patients. J Am Coll Surg 203(4):475-80, 2006. e-Pub 8/2006. PMID: 17000390.
30. Giordano SH, Duan Z, Kuo YF, Hortobagyi GN, Freeman J, Goodwin JS. Impact of a scientific presentation on community treatment patterns for primary breast cancer. J Natl Cancer Inst 98(6):382-8, 2006. PMCID: PMC1853252.
31. Giordano SH, Lee A, Kuo YF, Freeman J, Goodwin JS. Late gastrointestinal toxicity after radiation for prostate cancer. Cancer 107(2):423-32, 2006. PMID: 16779795.
32. Oh JL, Dryden MJ, Woodward WA, Yu TK, Tereffe W, Strom EA, Perkins GH, Middleton L, Hunt KK, Giordano SH, Oswald MJ, Domain D, Buchholz TA. Locoregional control of clinically diagnosed multifocal or multicentric breast cancer after neoadjuvant chemotherapy and locoregional therapy. J Clin Oncol 24(31):4971-5, 2006. PMID: 17075114.
33. Patt D, Gauthier AM, Giordano SH. Paclitaxel in breast cancer. Women's Health 2(1):11-21, 2006.
34. Luo R, Giordano SH, Freeman JL, Zhang D, Goodwin JS. Referral to medical oncology: a crucial step in the treatment of older patients with stage III colon cancer. Oncologist 11(9):1025-33, 2006. PMCID: PMC1913211.
35. Woodward WA, Giordano SH, Duan Z, Hortobagyi GN, Buchholz TA. Supraclavicular radiation for breast cancer does not increase the 10-year risk of stroke. Cancer 106(12):2556-62, 2006. PMID: 16691617.
36. Giordano SH, Duan Z, Kuo YF, Hortobagyi GN, Goodwin JS. Use and outcomes of adjuvant chemotherapy in older women with breast cancer. J Clin Oncol 24(18):2750-6, 2006. PMID: 16782915.
37. Giordano SH. A review of the diagnosis and management of male breast cancer. Oncologist 10(7):471-9, 2005. PMID: 16079314.
38. Giordano SH, Perkins GH, Broglio K, Garcia SG, Middleton LP, Buzdar AU, Hortobagyi GN. Adjuvant systemic therapy for male breast carcinoma. Cancer 104(11):2359-64, 2005. PMID: 16270318.
39. Giordano SH, Hortobagyi GN, Kau SW, Theriault RL, Bondy ML. Breast cancer treatment guidelines in older women. J Clin Oncol 23(4):783-91, 2005. PMID: 15681522.
40. Patt DA, Goodwin JS, Kuo YF, Freeman JL, Zhang DD, Buchholz TA, Hortobagyi GN, Giordano SH. Cardiac morbidity of adjuvant radiotherapy for breast cancer. J Clin Oncol 23(30):7475-82, 2005. e-Pub 9/2005. PMID: 16157933.
41. Yen TW, Hunt KK, Ross MI, Mirza NQ, Babiera GV, Meric-Bernstam F, Singletary SE, Symmans WF, Giordano SH, Feig BW, Ames FC, Kuerer HM. Predictors of invasive breast cancer in patients with an initial diagnosis of ductal carcinoma in situ: a guide to selective use of sentinel lymph node biopsy in management of ductal carcinoma in situ. J Am Coll Surg 200(4):516-26, 2005. PMID: 15804465.
42. Giordano SH, Kuo YF, Freeman JL, Buchholz TA, Hortobagyi GN, Goodwin JS. Risk of cardiac death after adjuvant radiotherapy for breast cancer. J Natl Cancer Inst 97(6):419-24, 2005. PMCID: PMC1853253.
43. Buzdar AU, Ibrahim NK, Francis D, Booser DJ, Thomas ES, Theriault RL, Pusztai L, Green MC, Arun BK, Giordano SH, Cristofanilli M, Frye DK, Smith TL, Hunt KK, Singletary SE, Sahin AA, Ewer MS, Buchholz TA, Berry D, Hortobagyi GN. Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer. J Clin Oncol 23(16):3676-85, 2005. e-Pub 2/2005. PMID: 15738535.
44. Hennessy BT, Krishnamurthy S, Giordano S, Buchholz TA, Kau SW, Duan Z, Valero V, Hortobagyi GN. Squamous cell carcinoma of the breast. J Clin Oncol 23(31):7827-35, 2005. PMID: 16258085.
45. Du XL, Chan W, Giordano S, Geraci JM, Delclos GL, Burau K, Fang S. Variation in modes of chemotherapy administration for breast carcinoma and association with hospitalization for chemotherapy-related toxicity. CANCER 104(5):913-24, 2005. PMID: 15991239.
46. Giordano SH, Cohen DS, Buzdar AU, Perkins G, Hortobagyi GN. Breast carcinoma in men: a population-based study. Cancer 101(1):51-7, 2004. PMID: 15221988.
47. Giordano SH, Buzdar AU, Smith TL, Kau SW, Yang Y, Hortobagyi GN. Is breast cancer survival improving? Cancer 100(1):44-52, 2004. PMID: 14692023.
48. Giordano SH Hortobagyi GN. Inflammatory breast cancer: clinical progress and the main problems that must be addressed. Breast Cancer Res 5(6):284-8, 2003. e-Pub 8/2003. PMCID: PMC314400.
49. Giordano SH. Update on locally advanced breast cancer. Oncologist 8(6):521-30, 2003. PMID: 14657530.
50. Giordano SH, Booser DJ, Murray JL, Ibrahim NK, Rahman ZU, Valero V, Theriault RL, Rosales MF, Rivera E, Frye D, Ewer M, Ordonez NG, Buzdar AU, Hortobagyi GN. A detailed evaluation of cardiac toxicity: a phase II study of doxorubicin and one- or three-hour-infusion paclitaxel in patients with metastatic breast cancer. Clin Cancer Res 8(11):3360-8, 2002. PMID: 12429622.
51. Giordano SH, Buzdar AU, Hortobagyi GN. Breast cancer in men. Ann Intern Med 137(8):678-87, 2002. PMID: 12379069.
52. Giordano SH, Valero V, Buzdar AU, Hortobagyi GN. Efficacy of anastrozole in male breast cancer. Am J Clin Oncol 25(3):235-7, 2002. PMID: 12040279.

Last updated: 9/10/2009