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Stephen F. Kry, Ph.D.

Present Title & Affiliation

Primary Appointment

Assistant Professor, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Member, Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston, Houston, TX

Bio Statement

 

My long-term professional goal is to improve the safety and efficacy of radiotherapy treatment for cancer patients by improving the quality and consistency of such treatments. The proposed project works directly towards this goal by ensuring consistent and quality radiotherapy is delivered to patients enrolled in clinical trials. This will have immediate benefit to those specific patients on clinical trial, and will benefit all patients in the long-term by ensuring that clinical trials generate the optimal results. I am well suited to be a co-investigator on this grant because I have substantial experience in evaluating doses delivered in a radiotherapy setting. This includes clinical experience, working with a wide range of radiotherapy patients undergoing contemporary radiotherapy. It also includes research in patient dosimetry, patient setup, and institution credentialing for clinical trials. Through these experiences I have a solid understanding of radiotherapy as it is currently practiced, the limitations of current practice, and what is necessary to ensure consistent, quality, treatments.

Education & Training

Degree-Granting Education

2007 The University of Texas MD Anderson Cancer Center, Houston, TX, PHD, Medical Physics
2003 The University of Texas MD Anderson Cancer Center, Houston, TX, MS, Medical Physics
1999 University of British Columbia, Vancouver, Canada, B.Sc., Honors Physics

Experience/Service

Academic Appointments

Instructor, Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2007-2010
Associate Member, Associate Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston, Houston, TX, 2007-2010
Graduate Research Assistant, Department of Radiation Physics, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2000-2007

Honors and Awards

2011 "The clinical impact of the couch top and rails on IMRT and arc therapy” selected as a Featured Article by Physics in Medicine and Biology
2011 “The clinical impact of the couch top and rails on IMRT and arc therapy” featured in Medical Physics Web: “Couch attenuation undermines plan quality”

Professional Memberships

Radiation Detection and Treatment Planning AAPM Subcommittee
Member, 2009-present

Selected Publications

Peer-Reviewed Original Research Articles

1. Scarboro SB, Kry SF. Characterisation of energy response of Al2O3:C optically simulated luminescent dosimeters (OSLDs) using cavity theory. Radiat Prot Dosimetry. e-Pub 5/2012. PMID: 22653437.
2. Kry SF, Jones J, Childress NL. Implementation and evaluation of an end-to-end IGRT test. J Appl Clin Med Phys 13(5):3939, 2012. e-Pub 9/2012. PMID: 22955659.
3. Kry SF, Popple R, Molineu A, Followill DS. Ion recombination correction factors (Pion) for Varian TrueBeam high-dose-rate therapy beams. J Appl Clin Med Phys 13(6):3803, 2012. e-Pub 11/2012. PMID: 23149774.
4. Followill DS, Kry SF, Qin L, Lowenstein J, Molineu A, Alvarez P, Aguirre JF, Ibbott GS. The Radiological Physics Center's standard dataset for small field size output factors. J Appl Clin Med Phys 13(5):3962, 2012. e-Pub 8/2012. PMID: 22955664.
5. Beyer GP, Kry SF, Espenhahn E, Rini C, Boyles E, Mann G. Evaluation of an implantable MOSFET dosimeter designed for use with hypo-fractionated external beam treatments and its applications for breast and prostate treatments. Med Phys 38(8):4881-4887, 8/2011. PMID: 21928659.
6. Kerns JR, Kry SF, Sahoo N, Followill DS, Ibbott GS. Angular dependence of the nanoDot OSL dosimeter. Med Phys 38(7):3955-62, 7/2011. PMCID: PMC3133805.
7. Scarboro SB, Followill DS, Howell RM, Kry SF. Variations in photon energy spectra of a 6 MV beam and their impact on TLD response. Med Phys 38(5):2619-2628, 5/2011. PMCID: PMC3107829.
8. Berrington de Gonzalez A, Curtis RE, Kry SF, Gilbert E, Lamart S, Berg CD, Stovall M, Ron E. Proportion of second cancers attributable to radiotherapy treatment in adults: a cohort study in the US SEER cancer registries. Lancet Oncol 12(4):353-60, 4/2011. PMCID: PMC3086738.
9. Kry SF, Johnson JL, White RA, Howell RM, Kudchadker RJ, Gillin MT. Neutron-induced electronic failures around a high-energy linear accelerator. Med Phys 38(1):34-9, 1/2011. PMID: 21361172.
10. Pulliam KB, Howell RM, Followill DS, Luo D, White RA, Kry SF. Clinical impact of the couch top and rails on IMRT and Arc Therapy. Phys. Med. Biol. 38:4881-4887, 2011.
11. Berringlor de Gonzalez A, Curtis R, Kry SF, Gilbert E, Lamart S, Berg CD, Stovall M, Ron E. The proportion of second cancers attributable to radiotherapy treatment in adults: a prospective cohort study in the US SEER cancer registries. Lancet Oncology 12:353-60, 2011.
12. Howell RM, Scarboro SB, Kry SF, Yaldo DZ. Accuracy of out-of-field dose calculations by a commercial treatment planning system. Phys Med Biol 55(23):6999-7008, 12/7/2010. e-Pub 11/12/2010. PMCID: PMC3152254.
13. Scarboro SB, Stovall M, White A, Smith SA, Yaldo D, Kry SF, Howell RM. Effect of organ size and position on out-of-field dose distributions during radiation therapy. Phys Med Biol 55(23):7025-7036, 12/7/2010. e-Pub 11/12/2010. PMCID: PMC3152250.
14. Howell RM, Scarboro SB, Taddei PJ, Krishnan S, Kry SF, Newhauser WD. Methodology for determining doses to in-field, out-of-field and partially in-field organs for late effects studies in photon radiotherapy. Phys Med Biol 55(23):7009-7023, 12/2010. e-Pub 11/2010. PMCID: PMC3001332.
15. Serago CF, Burmeister JW, Dunscombe PB, Gale AA, Hendee WR, Kry SF, Wuu CS. Recommended ethics curriculum for medical physics graduate and residency programs. Report of Task Group 159. Med Phys 37(8):4495-4500, 8/2010. PMID: 20879608.
16. Wang Z, Howell RM, Burgett EA, Kry SF, Hertel NE, Salehpour M. Calibration of indium response functions in an Au-In-BSE system up to 800 MeV. Radiat Prot Dosimetry 139(4):565-573, 6/2010. e-Pub 12/15/2009. PMCID: PMC2909792.
17. Kry SF, Vassiliev ON, Mohan R. Out-of-field photon dose following removal of the flattening filter from a medical accelerator. Phys Med Biol 55(8):2155-2166, 4/21/2010. e-Pub 3/19/2010. PMID: 20305334.
18. Price MJ, Kry SF, Eifel PJ, Salehpour M, Mourtada F. Dose perturbation due to the polysulfone cap surrounding a Fletcher-Williamson colpostat. J Appl Clin Med Phys 11(1):3146, 2010. e-Pub 1/28/2010. PMID: 20160700.
19. Howell RM, Kry SF, Burgett E, Followill D, Hertel NE. Effects of tertiary MLC configuration on secondary neutron spectra from 18-MV x-ray beams for the Varian 21 EX linear accelerator. Med Phys 36(9):4039-4046, 9/2009. PMCID: PMC2738743.
20. Howell RM, Kry SF, Burgett E, Hertel NE, Followill DS. Secondary neutron spectra from modern Varian, Siemens, and Elekta linacs with multileaf collimators. Med Phys 36(9):4027-4038, 9/2009. PMCID: PMC2738742.
21. Kry SF, Salehpour M, Titt U, White RA, Stovall M, Followill D. Monte Carlo study shows no significant difference in second cancer risk between 6- and 18-MV intensity-modulated radiation therapy. Radiother Oncol 91(1):132-7, 4/2009. e-Pub 1/13/2009. PMID: 19147246.
22. Kry SF, Howell RM, Salehpour M, Followill DS. Neutron spectra and dose equivalents calculated in tissue for high-energy radiation therapy. Med Phys 36(4):1244-1250, 4/2009. PMCID: PMC2736753.
23. Kry SF, Howell RM, Polf J, Mohan R, Vassiliev ON. Treatment vault shielding for a flattening filter free medical linear accelerator. Phys Med Biol 54(5):1265-1273, 3/7/2009. e-Pub 2/3/2009. PMID: 19190359.
24. Wang Z, Howell RM, Kry SF, Burgett EA, Hertel NE, Salehpour MN. Characterization of a gold-and-indium dual-activation-foil-based bonner sphere system. Nuclear Technology 168:603-609, 2009.
25. Wang Z, Kry SF, Howell RM, Salehpour M. Comparison of unfolding methods for determining neutron spectrum and ambient dose equivalent. Nuclear Technology 168:610-614, 2009.
26. Kry SF, Price M, Wang Z, Mourtada F, Salehpour M. Investigation into the Use of a MOSFET Dosimeter as an Implantable Fiducial Marker. J Appl Clin Med Phys 10(1):22-32, 2009. PMID: 19223838.
27. Howell RM, Burgett E, Hertel NE, Kry SF, Wang Z, Salehpour M. Measurement of high-energy neutron spectra with Bonner Extension (BSE) system. Nuclear Technology 168:333-339, 2009.
28. Vassiliev ON, Kry SF, Chang JY, Balter PA, Titt U, Mohan R. Stereotactic radiotherapy for lung cancer using a flattening filter free Clinac. J Appl Clin Med Phys 10(1):2880, 2009. PMID: 19223837.
29. Johnson J, Nelson R, Hickman V, Kry SF. The cover up: skin dose increase during external beam therapy. Radiation Therapist 18:9-12, 2009.
30. Kry SF, Howell RM, Titt U, Salehpour M, Mohan R, Vassiliev ON. Energy Spectra, Sources, and Shielding Considerations for Neutrons Generated by a Flattening Filter-Free Clinac. Med Phys 35(5):1906-1911, 5/2008. PMID: 18561666.
31. Kry SF, Titt U, Followill D, Pönisch F, Vassiliev ON, White RA, Stovall M, Salehpour M. A Monte Carlo model for out-of-field dose calculation from high-energy photon therapy. Med Phys 34(9):3489-99, 9/2007. PMID: 17926952.
32. Vassiliev ON, Kry SF, Kuban DA, Salehpour M, Mohan R, Titt U. Treatment-planning study of prostate cancer intensity-modulated radiotherapy with a Varian Clinac operated without a flattening filter. Int J Radiat Oncol Biol Phys 68(5):1567-71, 8/2007. e-Pub 6/2007. PMID: 17544596.
33. Kry SF, Followill D, White RA, Stovall M, Kuban DA, Salehpour M. Uncertainty of calculated risk estimates for secondary malignancies after radiotherapy. Int J Radiat Oncol Biol Phys 68(4):1265-71, 7/2007. PMID: 17637398.
34. Kry SF, Starkschall G, Antolak JA, Salehpour M. Evaluation of the Accuracy of Fetal Dose Estimates Using TG-36 Data. Med Phys 34(4):1193-1197, 2007. PMID: 17500450.
35. Vassiliev ON, Titt U, Kry SF, Mohan R, Gillin MT. Radiation safety survey on a flattening filter-free medical accelerator. Radiat Prot Dosimetry 124(2):187-90, 2007. e-Pub 8/6/2007. PMID: 17681966.
36. Kry SF, Titt U, Poenisch F, Vassiliev ON, Salehpour M, Gillin M, Mohan R. Reduced Neutron Production Through Use of a Flattening Filter Free Accelerator. Int J Radiat Oncol Biol Phys 68(4):1260-1264, 2007. PMID: 17637397.
37. Kry SF, Price MJ, Followill D, Mourtada F, Salehpour M. The Use of LiF (TLD-100) as an Out-of Field Dosimeter. J Appl Clin Med Phys 8(4):169-175, 2007. PMID: 18449155.
38. Kry SF, Titt U, Poenisch F, Followill D, Vassiliev ON, White RA, Mohan R, Salehpour M. A Monte Carlo Model for Calculating Out-of-Field Dose from a Varian 6-MV Beam. Med Phys 33(11):4405-4413, 2006. PMID: 17153419.
39. Vassiliev ON, Titt U, Poenisch F, Kry SF, Mohan R, Gillin MT. Dosimetric Properties of Photon Beams From a Flattening Filter Free Clinical Accelerator. Phys Med Biol 51(7):1907-1917, 2006. e-Pub 3/2006. PMID: 16552113.
40. Ponisch F, Titt U, Kry SF, Vassiliev ON. MCNPX Simulation of a Multileaf Collimator. Med Phys 33(2):402-404, 2006. PMID: 16532947.
41. Titt U, Vassiliev ON, Ponisch F, Kry SF, Mohan R. Monte Carlo Study of Backscatter in a Flattening Filter Free Clinical Accelerator. Med Phys 33(9):3270-3273, 2006. PMID: 17022221.
42. Vassiliev ON, Titt U, Kry SF, Ponisch F, Gillin MT, Mohan R. Monte Carlo Study of Photon Fields from a Flattening Filter Free Clinical Accelerator. Med Phys 33(4):820-827, 2006. PMID: 16696457.
43. Ponisch F, Titt U, Vassiliev ON, Kry SF, Mohan R. Properties of Unflattened Photon Beams Shaped by a Multi Leaf Collimator. Med Phys 33(6):1738-1746, 2006. PMID: 16872081.
44. Kry SF, Salehpour M, Followill DS, Stovall M, Kuban DA, White RA, Rosen II. The calculated risk of fatal secondary malignancies from intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 62(4):1195-203, 7/2005. PMID: 15990025.
45. Kry SF, Salehpour M, Followill D, Stovall M, Kuban D, White RA, Rose I. Out of Field Photon and Neutron Dose Equivalents from Step and Shoot Intensity Modulated Radiation Therapy. Int J Radiat Oncol Biol Phys 62(4)(4):1204-1216, 2005. PMID: 15990026.
46. Followill D, Stovall M, Kry SF, Ibbott G. Neutron Source Strength Measurements for Varian, Siemens, Elekta, and General Electric Linear Accelerators. J Appl Clin Med Phys 4(3):189-194, 2003. PMID: 12841788.
47. Suprunowicz R, Butler RM, Ford COK, Kry SF. An Experimental Investigation of Conbergent Flow to Horizontal Wells. Jour of Canadian Petroleum Technology 37(10):51-57, 1998.

Editorials

1. Kry SF, Howell RM. Invited commentary: Breast Disease: A year book quarterly. commenatry on: Berrington de Gonzalez et al., Second solid cancers after radiotherapy for breast cancer in SEER cancer registries. Br J Cancer 102:220-226, 2009.
2. Kry SF, Howell RM. Invited commentary: Breast Disease: A year book quarterly. Commenatry on: Mery et al., Second sarcomas after radiotherapy for breast cancer: sustained risk and poor survival. Cancer 115:4055-4063, 2009.
3. Howell RM, Kry SF. Invited commentary: Breast Disease: A year book quarterly. Commentary on: Inskip et al., Radiation dose and breast cancer risk in the childhood cancer survivor study. J Clin Oncol 27:3901-3907, 2009.
4. Howell RM, Kry SF, Stovall M. Invited commentary: Breast Disease: A year book quarterly. Commentary on: Yadav et al., Nonbreast second maglignancies after treatment of primary breast cancer. Int J Radiat Oncol Biol Phys 73:1489-1492, 2009.

Grant & Contract Support

Title: Late Effects Following Radiotherapy
Funding Source: UT MD Anderson Cancer Center
Role: Principal Investigator
Duration: 1/1/2011 - 1/1/2014
 
Title: Radiological Physics Center
Funding Source: NIH/NCI
Role: Co-Investigator
Duration: 1/1/2011 - 12/31/2013
 
Title: A calculation method for patient specific dosimetry for epidemiological studies of radiation induced second cancers
Funding Source: NIH/NCI
Role: Co-Principal Investigator
Principal Investigator: Howell
Duration: 12/1/2009 - 11/30/2011
 
Title: Phantom Measurements and Validation of High-Dose DVS
Funding Source: Sicel
Role: Principal Investigator
Duration: 12/1/2007 - 1/31/2008

Last updated: 5/20/2013