The benefits of proton therapy
Steven J. Frank, M.D.
Department of GU Radiation Oncology, Division of Radiation Oncology
About Dr. Frank
Steven J. Frank, MD, is an endowed tenured professor of Radiation Oncology and holds the Bessie McGoldrick Professorship in Clinical Research at The University of Texas MD Anderson Cancer Center. Dr. Frank is the Executive Director of the Particle Therapy Institute and Deputy Head of Strategy for the Division of Radiation Oncology. Dr Frank was instrumental in facilitating the restructuring of MD Anderson’s proton therapy center through an asset acquisition and a subsequent expansion of a second proton therapy center to advance Intensity Modulated Proton Therapy (IMPT). Dr. Frank is amongst the first, if not the first, to use IMPT to treat head and neck tumors, and he is the Principal Investigator of an NIH/NCI-sponsored multi-institutional Phase II/III randomized trial in advanced stage oropharyngeal cancer that compares outcomes after chemoradiation given by IMRT versus IMPT. Dr. Frank has approximately 300 peer-reviewed publications, has authored many book chapters, and has recently published the first textbook on Proton Therapy based on the MD Anderson experience. Dr. Frank’s lab is studying the biologic enhancement factor of proton therapy and FLASH radiotherapy for head and neck cancer, as well as MRI-Assisted Radiosurgery (MARS) as the next generation of prostate brachytherapy. Dr. Frank’s expertise in MRI radiotherapy has led to the development and FDA approval of multiple novel positive-contrast implantable markers for use in MRI-guided LDR and HDR prostate brachytherapy and external beam radiation therapy. As founder of the company, C4 Imaging, Dr. Frank has developed the MRI marker technology at MD Anderson, has been granted 31 national and international patents, developed three FDA approved products, and has established MRI-Assisted Radiosurgery (MARS) at MD Anderson for the treatment of prostate cancer. He has funding from the NIH, the Prostate Cancer Foundation, the Texas Ignition Fund, Hitachi and MD Anderson, and he has also raised multiple rounds of private equity financing to advance the C4 technology. Dr. Frank has served as the past President and Chairman of the Board of the American Brachytherapy Society and is the 2023 recipient of the Ulrich Henschke Award, the highest honor awarded by the ABS on a practitioner of brachytherapy. Dr. Frank has served as the chair for the head and neck oral boards for the American Board of Radiology over the last six years and will join the Board of Trustees in October 2023. Prior to entering medicine, Dr. Frank served in the military as a U.S. Navy Diver and submarine officer on the fast attack nuclear submarine USS Batfish (SSN-681). He is married to Dr. Ivy Frank, a veterinarian, and his hobbies include golf, flying and coaching softball for his four daughters.
Present Title & Affiliation
Primary Appointment
Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Deputy Division Head, Strategic Programs, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Medical Director, Department of Proton Therapy Center, Division of Radiation Oncology, The UT MD Anderson Cancer Center Proton Therapy Center, Houston, TX
Director of Advanced Technologies, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Adjunct Associate Professor, Department of Radiation Oncology, Division of Diagnostic Imaging, Baylor College of Medicine, Houston, TX
Adjunct Associate Professor, Department of Radiation Oncology, Division of Radiation Oncology, University Medical Center Utrecht, Utrecht
Education & Training
Degree-Granting Education
2000 | Emory University School of Medicine, Atlanta, GA, USA, MD, General Science |
1995 | U.S. Naval Nuclear Propulsion Program, Washington, DC, USA, Nuclear Engineer, Nuclear Engineering |
1991 | University of Pennsylvania, Philadelphia, PA, USA, BA, History |
Postgraduate Training
2004-2004 | Clinical Fellowship, Prostate Brachytherapy, Seattle Prostate Institute, Seattle, WA |
2001-2005 | Clinical Residency, Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX |
2000-2001 | Research Internship, Internal Medicine, Emory University School of Medicine, Atlanta, GA |
1991-1996 | Nuclear Engineer, Nuclear Engineering, United States Naval Nuclear Propulsion Program, Washington, DC |
Board Certifications
2006 | American Board of Radiology |
Experience & Service
Academic Appointments
Adjunct Associate Professor, Department of Radiation Oncology, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX, 2012 - 2013
Associate Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2016
Adjunct Assistant Professor, Division of Radiation Oncology, Baylor College of Medicine, Houston, TX, 2010 - 2012
Assistant Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2005 - 2011
Administrative Appointments/Responsibilities
Deputy Department Chair, Strategic Programs, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2017
Co-Chair, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, 2014 - 2014
Committee Chair RadOnc 2014, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2014
Committee Chair RadOnc 2012, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2012
Committee Chair, Radiation Oncology (Faculty) Mentoring Program, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - 2015
Committee Chair, RadOnc 2010, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2009 - 2010
Other Appointments/Responsibilities
Executive Committee, National Association for Proton Therapy (NAPT), McLean, VA, 2023 - Present
Trustee, American Board of Radiology (ABR), Tucson, AZ, 2023 - Present
Task Force (ROAPM), National Association for Proton Therapy (NAPT), McLean, VA, 2019 - 2022
Chair, Head and Neck Section of Oral Boards, American Board of Radiology, Tucson, AZ, 2015 - 2021
Head, Proton Head & Neck Program, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - Present
Member of the ABR H&N Committee, American Board of Radiology, Tucson, AZ, 2011 - 2021
Expert Panel Member, Texas Medical Board, Austin, TX, 2009 - 2014
Head, Prostate Brachytherapy Program, The University of Texas MD Anderson Cancer Center, Houston, TX, 2005 - Present
Institutional Committee Activities
Participant, Diversity, Equity and Inclusion (DEI) Champion, 2023 - 2023
Advisory Committee Member, Graduate School of Biomedical Sciences, 2017 - Present
Advisory Board, Physician Referrals Advisory Board, 2015 - Present
Faculty Associate, Institute for Cancer Care Innovation, 2014 - Present
Committee Member, PDC Oversight Committee, 2013 - 2014
Ambassador, Physician Relations Faculty Ambassador Program, 2013 - Present
Committee Chair, The Integration of MRI with Radiation Oncology, 2013 - 2013
Co-leader, The Center for Radiation Oncology Research Technology Working Group, 2013 - 2017
Committee Member, Clinical Safety and Effectiveness (CS&E), 2012 - Present
Co-leader, Research Funding Review Panel, Division of Radiation Oncology, 2012 - 2013
Committee Member, Proton Therapy Conference, 2011 - 2012
Committee Member, Institutional Research Grants - Clinical Study Section, 2011 - Present
Committee Member, Clinical and Research Informatics, 2010 - 2015
Committee Chair, Radiation Oncology (Faculty) Mentoring Program, 2010 - 2014
Committee Member, MD Anderson Physicians Network QA Committee - Head and Neck and Prostate Brachytherapy, 2009 - 2016
Committee Chair, MD Anderson Institutional Grand Rounds, 2008 - 2008
Board Member, Scientific Publications Advisory Board, 2008 - Present
Endowed Positions
Bessie McGoldrick Professorship in Clinical Cancer Research, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - Present
Consultantships
Consultant, Varian, Houston, TX, 2015 - 2020
Reviewer/Consultant, The University of Texas MD Anderson Physician's Network, Houston, TX, 2009 - 2015
Military or Other Governmental Service
Lieutenant, U. S. Navy, 1991 - 1996
Honors & Awards
2023 | Ulrich Henschke Award, American Brachy Society |
2023 | Dr. Prathap C. Reddy Oration Award - 2023, Apollo Proton Cancer Centre |
2022 | Fellow American Society of Radiation Oncology, ASTRO |
2020 | LEAN Bronze Certification, The University of Texas MD Anderson Cancer Center - Department of Radiation Oncology |
2020 | The James D. Cox Mentoring Award, The University of Texas MD Anderson Cancer Center |
2020 | Fellow of the American Brachytherapy Society, American Brachytherapy Society |
2018 | MD Anderson Cancer Center Endowed Professor |
2018 | Degree of Fellow of American College of Radiology, American College of Radiology |
2017 | Chairman of the Board, American Brachytherapy Society |
2016 | President, American Brachytherapy Society |
2015 | Vice President, American Brachytherapy Society |
2012 | Head of American Brachytherapy Society Resident Scholarship Program at The University of Texas MD Anderson Cancer Center, American Brachytherapy Society |
2009 | Best Doctors in America |
2008 | 2008 Young Investigator Award, Prostate Cancer Foundation |
2005 | 3rd International IMRT Treatment Planning Conference Travel Award |
2004 | American College of Radiology Council Steering Committee |
2004 | ASTRO Radiation Physics Committee |
2004 | Seattle Prostate Institute Brachytherapy Fellowship |
2003 | Association of Residents in Radiation Oncology Executive Board |
2003 | Residency Review Committee (RRC) for Radiation Oncology |
2003 | Texas Radiological Society Outstanding Resident Presentation Award |
2002 | Berlex Oncology Foundation Award |
2002 | Fletcher Society Resident Research Award |
2002 | RSNA Research Trainee Award |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Hartsell WF, Simone CB, Godes D, Maggiore J, Mehta MP, Frank SJ, Metz JM, Choi JI. Temporal Evolution and Diagnostic Diversification of Patients Receiving Proton Therapy in the United States: A Ten-Year Trend Analysis (2012 to 2021) From the National Association for Proton Therapy. Int J Radiat Oncol Biol Phys 119(4):1069-1077, 2024. e-Pub 2023. PMID: 38163519.
- Burus T, VanHelene AD, Rooney MK, Lang Kuhs KA, Christian WJ, McNair C, Mishra S, Paulino AC, Smith GL, Frank SJ, Warner JL. Travel-Time Disparities in Access to Proton Beam Therapy for Cancer Treatment. JAMA Netw Open 7(5):e2410670, 2024. e-Pub 2024. PMID: 38758559.
- Wang L, Ding Y, Bruno TL, Stafford RJ, Lin E, Bathala TK, Sanders JW, Ning MS, Ma J, Klopp AH, Venkatesan A, Wang J, Martirosyan KS, Frank SJ*. A Novel Positive-Contrast Magnetic Resonance Imaging Line Marker for High-Dose-Rate (HDR) MRI-Assisted Radiosurgery (MARS). Cancers (Basel) 16(10), 2024. e-Pub 2024. PMID: 38792000.
- Orlandi E, Fontana G, Licitra L, Tinelli C, Camarda AM, Grau C, Frank SJ*. Comprehensive insights on the underlying potential and advantage of proton therapy over intensity-modulated photon radiation therapy as highlighted in a wide real world data analysis. Radiother Oncol 193:110122, 2024. e-Pub 2024. PMID: 38309585.
- Goldfarb J, Fan J, de Sousa LG, Akhave N, Myers J, Goepfert R, Manisundaram K, Zhao J, Frank SJ, Moreno A, Ferrarotto R, Esmaeli B. Neoadjuvant Chemotherapy Alone or Combined with EGFR-Directed Targeted Therapy or Anti-PD-1 Immunotherapy for Locally Advanced Lacrimal Sac and Nasolacrimal Duct Carcinomas. Semin Ophthalmol:1-7. e-Pub 2024. PMID: 38500295.
- McCall NS, Frank SJ, Stokes WA. The Case for Allowing Proton Beam Therapy on Head and Neck Cooperative Group Studies. JAMA Oncol 10(3):289-290, 2024. PMID: 38206607.
- Goldberg H, Jiang X, Fan J, Zhao J, Ning J, Williams M, Frank SJ, Moreno A, Gunn B, Ferrarotto R, Esmaeli B. Lacrimal Gland Adenocarcinoma Clinicopathologic Features and Outcomes Compared With Those of Lacrimal Gland Adenoid Cystic Carcinoma. Ophthalmic Plast Reconstr Surg 40(4):419-425, 2024. e-Pub 2024. PMID: 38319188.
- Sosa AJ, Thames HD, Sanders JW, Choi SL, Nguyen QN, Mok H, Ron Zhu X, Shah S, Mayo LL, Hoffman KE, Tang C, Lee AK, Pugh TJ, Kudchadker R, Frank SJ*. Proton therapy for the management of localized prostate cancer: Long-term clinical outcomes at a comprehensive cancer center. Radiother Oncol 188:109854, 2023. e-Pub 2023. PMID: 37597805.
- Zhao Z, Frank SJ, Ning J, Zhao J, Jiang X, Wang XA, Schefler AC, Hanna E, Moreno A, Gunn B, Ferrarotto R, Esmaeli B. Visual outcome and ocular complications in patients with lacrimal gland carcinoma after eye-sparing surgery and adjuvant radiation therapy. Br J Ophthalmol 107(12):1914-1919, 2023. e-Pub 2023. PMID: 36229179.
- Choi JI, Simone CB, Lozano A, Frank SJ*. Advances and Challenges in Conducting Clinical Trials With Proton Beam Therapy. Semin Radiat Oncol 33(4):407-415, 2023. PMID: 37684070.
- Andring LM, Abu-Gheida I, Bathala T, Yoder AK, Manzar GS, Maldonado JA, Frank SJ, Choi S, Nguyen QN, Hoffman K, McGuire SE, Mok H, Aparicio A, Chapin BF, Tang C. Definitive local therapy for T4 prostate cancer associated with improved local control and survival. BJU Int 132(3):307-313, 2023. e-Pub 2023. PMID: 37057728.
- Michalski JM, Winter KA, Prestidge BR, Sanda MG, Amin M, Bice WS, Gay HA, Ibbott GS, Crook JM, Catton CN, Raben A, Bosch W, Beyer DC, Frank SJ, Papagikos MA, Rosenthal SA, Barthold HJ, Roach M, Moughan J, Sandler HM. Effect of Brachytherapy With External Beam Radiation Therapy Versus Brachytherapy Alone for Intermediate-Risk Prostate Cancer: NRG Oncology RTOG 0232 Randomized Clinical Trial. J Clin Oncol 41(24):JCO2201856, 2023. e-Pub 2023. PMID: 37315297.
- Rooney MK, Andring LM, Corrigan KL, Bernard V, Williamson TD, Fuller CD, Garden AS, Gunn B, Lee A, Moreno AC, Morrison WH, Phan J, Rosenthal DI, Spiotto M, Frank SJ*. Hypothyroidism following Radiotherapy for Head and Neck Cancer: A Systematic Review of the Literature and Opportunities to Improve the Therapeutic Ratio. Cancers (Basel) 15(17), 2023. e-Pub 2023. PMID: 37686597.
- Corkum MT, Buyyounouski MK, Chang AJ, Chung HT, Chung P, Cox BW, Crook JM, Davis BJ, Frank SJ, Henriquez I, Horwitz EM, Hoskin P, Hsu IC, Keyes M, King MT, Kollmeier MA, Krauss DJ, Kukielka AM, Morton G, Orio PF, Pieters BR, Potters L, Rossi PJ, Showalter TN, Solanki AA, Song D, Vanneste B, Vigneault E, Wojcieszek PA, Zelefsky MJ, Kamrava M. Salvage Prostate Brachytherapy in Radiorecurrent Prostate Cancer: An International Delphi Consensus Study. Radiother Oncol 184:109672, 2023. e-Pub 2023. PMID: 37059334.
- Cao W, Li Y, Zhang X, Poenisch F, Yepes P, Sahoo N, Grosshans D, McGovern S, Gunn GB, Frank SJ, Zhu XR. Intensity modulated proton arc therapy via geometry-based energy selection for ependymoma. J Appl Clin Med Phys 24(7):e13954, 2023. e-Pub 2023. PMID: 36913484.
- Tang C, Sanders J, Thames H, Swanson DM, Crook JM, Bruno T, Blanchard P, Ciezki J, Keyes M, Song D, Singh T, Merrick G, Stock R, Sullivan FJ, Mok H, Millar J, Frank SJ*. Outcomes after PD-103 versus I-125 for low dose rate prostate brachytherapy monotherapy: An international, multi-institutional study. Radiother Oncol 183:109599, 2023. e-Pub 2023. PMID: 36889593.
- Lee NY, Harris J, Kim J, Garden A, Mechalakos J, Pfister DG, Chan ATC, Hu K, Colevas AD, Frank S, Shenouda G, Bar-Ad V, Waldron JN, Harari PM, Raben A, Torres-Saavedra P, Le QT. Long-term Outcomes of Bevacizumab and Chemoradiation for Locoregionally Advanced Nasopharyngeal Carcinoma: A Nonrandomized Controlled Trial. JAMA Netw Open 6(6):e2316094, 2023. e-Pub 2023. PMID: 37266942.
- Vazquez I, Gronberg MP, Zhang X, Court LE, Zhu XR, Frank SJ, Yang M. A deep learning-based approach for statistical robustness evaluation in proton therapy treatment planning: a feasibility study. Phys Med Biol 68(9), 2023. e-Pub 2023. PMID: 37040785.
- Zhao J, Jiang X, Hanna E, Su SY, Moreno A, Gunn B, Frank SJ, Ferrarotto R, Ning J, Esmaeli B. Orbital and periocular complications in patients with sinonasal tumours with orbital invasion. Br J Ophthalmol. e-Pub 2023. PMID: 36707226.
- Frank SJ. A CALL TO ARMS: The Case for MRI-Assisted Radiosurgery (MARS) vs. Stereotactic Body Radiation Therapy or Robotic-Assisted Radical Prostatectomy. Brachytherapy 22(1):12-14, 2023. PMID: 36725197.
- Maroongroge S, De B, Woodhouse KD, Bassett RL, Lee P, Bloom ES, Smith GL, Frank SJ, Li J, Perkins G, Das P, Koong AC, Smith BD, Wang C. Physician Perspectives on Telemedicine in Radiation Oncology. Adv Radiat Oncol 8(2):101005, 2023. e-Pub 2022. PMID: 36311822.
- Sanders JW, Tang C, Kudchadker RJ, Venkatesan AM, Mok H, Hanania AN, Thames HD, Bruno TL, Starks C, Santiago E, Cunningham M, Frank SJ*. Uncertainty in magnetic resonance imaging-based prostate postimplant dosimetry: Results of a 10-person human observer study, and comparisons with automatic postimplant dosimetry. Brachytherapy 22(6):822-832, 2023. e-Pub 2023. PMID: 37716820.
- Ng SP, Cardenas CE, Bahig H, Elgohari B, Wang J, Johnson JM, Moreno AC, Shah SJ, Garden AS, Phan J, Gunn GB, Frank SJ, Ding Y, Na L, Yuan Y, Urbauer D, Mohamed ASR, Rosenthal DI, Morrison WH, MacManus MP, Fuller CD. Changes in Apparent Diffusion Coefficient (ADC) in Serial Weekly MRI during Radiotherapy in Patients with Head and Neck Cancer: Results from the PREDICT-HN Study. Curr Oncol 29(9):6303-6313, 2022. e-Pub 2022. PMID: 36135064.
- Yang M, Wang X, Guan F, Titt U, Iga K, Jiang D, Takaoka T, Tootake S, Katayose T, Umezawa M, Schüler E, Frank SJ, Lin SH, Sahoo N, Koong AC, Mohan R, Zhu XR. Adaptation and dosimetric commissioning of a synchrotron-based proton beamline for FLASH experiments. Phys Med Biol 67(16), 2022. e-Pub 2022. PMID: 35853442.
- Taku N, Chronowski G, Brandon Gunn G, Morrison WH, Gross ND, Moreno AC, Ferrarotto R, Frank SJ, Fuller CD, Goepfert RP, Phan J, Lai SY, Reddy JP, Rosenthal DI, Garden AS. Unilateral Radiotherapy for Tonsillar Cancer: Treatment Outcomes in the Era of Human Papilloma Virus (HPV), Positron-emission Tomography (PET) and Intensity-modulated Radiation Therapy (IMRT). Int J Radiat Oncol Biol Phys 113(5):1054-1062, 2022. e-Pub 2022. PMID: 35504500.
- Chen M, Wang Z, Jiang S, Sun J, Wang L, Sahoo N, Brandon Gunn G, Frank SJ, Xu C, Chen J, Nguyen QN, Chang JY, Liao Z, Ronald Zhu X, Zhang X. Predictive performance of different NTCP techniques for radiation-induced esophagitis in NSCLC patients receiving proton radiotherapy. Sci Rep 12(1):9178, 2022. e-Pub 2022. PMID: 35655073.
- Sanders JW, Frank SJ*. Erratum to: Development and clinical implementation of SeedNet: A sliding-window convolutional neural network for radioactive seed identification in MRI-assisted radiosurgery (MARS). Magn Reson Med. 2019;81:3888-3900. Magn Reson Med 87(6):3024, 2022. e-Pub 2022. PMID: 35122300.
- Sanders JW, Mok H, Hanania AN, Venkatesan AM, Tang C, Bruno TL, Thames HD, Kudchadker RJ, Frank SJ*. Computer-aided segmentation on MRI for prostate radiotherapy, Part II: Comparing human and computer observer populations and the influence of annotator variability on algorithm variability. Radiother Oncol 169:132-139, 2022. e-Pub 2021. PMID: 34979213.
- Sanders JW, Mok H, Hanania AN, Venkatesan AM, Tang C, Bruno TL, Thames HD, Kudchadker RJ, Frank SJ*. Computer-aided segmentation on MRI for prostate radiotherapy, Part I: Quantifying human interobserver variability of the prostate and organs at risk and its impact on radiation dosimetry. Radiother Oncol 169:124-131, 2022. e-Pub 2021. PMID: 34921895.
- Sanders JW, Kudchadker RJ, Tang C, Mok H, Venkatesan AM, Thames HD, Frank SJ*. Prospective Evaluation of Prostate and Organs at Risk Segmentation Software for MRI-based Prostate Radiation Therapy. Radiol Artif Intell 4(2):e210151, 2022. e-Pub 2022. PMID: 35391775.
- Cardenas CE, Blinde SE, Mohamed ASR, Ng SP, Raaijmakers C, Philippens M, Kotte A, Al-Mamgani AA, Karam I, Thomson DJ, Robbins J, Newbold K, Fuller CD, Terhaard C, On Behalf Of The , Bahig H, Blanchard P, Dehnad H, Doornaert P, Elhalawani H, Frank SJ, Garden A, Gunn GB, Hamming-Vrieze O, Kamal M, Kasperts N, Lee LW, McDonald BA, McPartlin A, Meheissen MA, Morrison WH, Navran A, Nutting CM, Pameijer F, Phan J, Poon I, Rosenthal DI, Smid EJ, Sykes AJ. Comprehensive Quantitative Evaluation of Variability in MR-guided Delineation of Oropharyngeal Gross Tumor Volumes and High-risk Clinical Target Volumes: An R-IDEAL Stage 0 Prospective Study. Int J Radiat Oncol Biol Phys. e-Pub 2022. PMID: 35124134.
- Stieb S, Engeseth GM, Mohamed ASR, He R, Perez-Martinez I, Rock S, Deshpande TS, Garden AS, Rosenthal DI, Frank SJ, Gunn GB, Fuller CD. The influence of radiation dose on taste impairment in a prospective observational study cohort of oropharyngeal cancer patients. Acta Oncol 61(2):146-152, 2022. e-Pub 2022. PMID: 35060430.
- Sousa LG, Wang K, Torman D, Binks BJ, Rubin ML, Andersen CR, Lewis WE, Rivera MJ, Kaya D, El-Naggar AK, Hanna EY, Esmaeli B, Frank SJ, Bell D, Glisson BS, Rodon J, Meric-Bernstam F, Lee JJ, Ferrarotto R. Treatment patterns and outcomes of palliative systemic therapy in patients with salivary duct carcinoma and adenocarcinoma, not otherwise specified. Cancer 128(3):509-518, 2022. e-Pub 2021. PMID: 34661906.
- Engeseth GM, Hysing LB, Yepes P, Pettersen HES, Mohan R, Fuller CD, Stokkevåg CH, Wu R, Zhang X, Frank SJ, Gunn GB. Impact of RBE variations on risk estimates of temporal lobe necrosis in patients treated with intensity-modulated proton therapy for head and neck cancer. Acta Oncol 61(2):1-8, 2022. e-Pub 2021. PMID: 34534047.
- Lin SH, Liao K, Lei X, Verma V, Shaaban S, Lee P, Chen AB, Koong AC, Hoftstetter WL, Frank SJ, Liao Z, Shih YT, Giordano SH, Smith GL. Health Care Resource Utilization for Esophageal Cancer Using Proton versus Photon Radiation Therapy. Int J Part Ther 9(1):18-27, 2022. e-Pub 2022. PMID: 35774487.
- Kamrava M, Thaker N, Small W, Frank SJ*. Driving accountable care with brachytherapy. Brachytherapy 21(1):4-5, 2022. e-Pub 2021. PMID: 34930712.
- Thaker NG, Kudchadker RJ, Incalcaterra JR, Bathala TK, Kaplan RS, Agarwal A, Kuban DA, Frank BD, Das P, Feeley TW, Frank SJ*. Improving efficiency and reducing costs of MRI-Guided prostate brachytherapy using Time-Driven Activity-Based costing. Brachytherapy 21(1):49-54, 2022. e-Pub 2021. PMID: 34389265.
- van Dijk LV, Frank SJ, Yuan Y, Gunn B, Moreno AC, Mohamed ASR, Preston KE, Qing Y, Spiotto MT, Morrison WH, Lee A, Phan J, Garden AS, Rosenthal DI, Langendijk JA, Fuller CD. Proton Image-guided Radiation Assignment for Therapeutic Escalation via Selection of locally advanced head and neck cancer patients [PIRATES]: A Phase I safety and feasibility trial of MRI-guided adaptive particle radiotherapy. Clin Transl Radiat Oncol 32:35-40, 2022. e-Pub 2021. PMID: 34841093.
- Shah C, Vicini F, Beriwal S, Thaker N, Frank SJ, Rossi P, Orio P, Chang AJ, Joshi N, Campbell SR, Naghavi A, Chao S, Kamrava M, Deufel CL, Mourtada F, Suh JH. American brachytherapy society radiation oncology alternative payment model task force: Quality measures and metrics for brachytherapy. Brachytherapy 21(1):63-74, 2022. e-Pub 2021. PMID: 34732290.
- Engeseth GM, He R, Mirkovic D, Yepes P, Mohamed ASR, Stieb S, Fuller CD, Wu R, Zhang X, Hysing LB, Pettersen HES, Stokkevåg CH, Mohan R, Frank SJ, Gunn GB. Mixed Effect Modeling of Dose and Linear Energy Transfer Correlations With Brain Image Changes After Intensity Modulated Proton Therapy for Skull Base Head and Neck Cancer. Int J Radiat Oncol Biol Phys 111(3):684-692, 2021. e-Pub 2021. PMID: 34153379.
- King MT, Keyes M, Frank SJ, Crook JM, Butler WM, Rossi PJ, Cox BW, Showalter TN, Mourtada F, Potters L, Stock RG, Kollmeier MA, Zelefsky MJ, Davis BJ, Merrick GS, Orio PF. Low dose rate brachytherapy for primary treatment of localized prostate cancer: A systemic review and executive summary of an evidence-based consensus statement. Brachytherapy 20(6):1114-1129, 2021. e-Pub 2021. PMID: 34509378.
- Lindemann A, Patel AA, Tang L, Tanaka N, Gleber-Netto FO, Bartels MD, Wang L, McGrail DJ, Lin SY, Frank SJ, Frederick MJ, Myers JN, Osman AA. Combined Inhibition of Rad51 and Wee1 Enhances Cell Killing in HNSCC Through Induction of Apoptosis Associated With Excessive DNA Damage and Replication Stress. Mol Cancer Ther 20(7):1257-1269, 2021. e-Pub 2021. PMID: 33947685.
- Cao J, Zhang X, Jiang B, Chen J, Wang X, Wang L, Sahoo N, Zhu XR, Ye R, Blanchard P, Garden AS, Fuller CD, Gunn GB, Frank SJ*. Intensity-modulated proton therapy for oropharyngeal cancer reduces rates of late xerostomia. Radiother Oncol 160:32-39, 2021. e-Pub 2021. PMID: 33839202.
- Elhalawani H, Cardenas CE, Volpe S, Barua S, Stieb S, Rock CB, Lin T, Yang P, Wu H, Zaveri J, Elgohari B, Abdallah LE, Jethanandani A, Mohamed ASR, Court LE, Hutcheson KA, Brandon Gunn G, Rosenthal DI, Frank SJ, Garden AS, Rao A, Fuller CD. 18FDG positron emission tomography mining for metabolic imaging biomarkers of radiation-induced xerostomia in patients with oropharyngeal cancer. Clin Transl Radiat Oncol 29:93-101, 2021. e-Pub 2021. PMID: 34195391.
- Taku N, Wang L, Garden AS, Rosenthal DI, Gunn GB, Morrison WH, Fuller CD, Phan J, Reddy JP, Moreno AC, Spiotto MT, Chronowski G, Shah SJ, Mayo LL, Gross ND, Ferrarotto R, Zhu XR, Zhang X, Frank SJ*. Proton Therapy for HPV-Associated Oropharyngeal Cancers of the Head and Neck: a De-Intensification Strategy. Curr Treat Options Oncol 22(6):54, 2021. e-Pub 2021. PMID: 34086150.
- Grossberg AJ, Rock CD, Edwards J, Mohamed ASR, Ruzensky D, Currie A, Rosemond P, Phan J, Gunn GB, Frank SJ, Morrison WH, Garden AS, Fuller CD, Rosenthal DI. Bioelectrical impedance analysis as a quantitative measure of sarcopenia in head and neck cancer patients treated with radiotherapy. Radiother Oncol 159:21-27, 2021. e-Pub 2021. PMID: 33736997.
- Allen CJ, Eska JS, Thaker NG, Feeley TW, Kaplan RS, Huey RW, Tzeng CD, Lee JE, Frank SJ, Aloia TA, Gottumukkala V, Katz MHG. Developing a Value Framework: Utilizing Administrative Data to Assess an Enhanced Care Initiative. J Surg Res 262:115-120, 2021. e-Pub 2021. PMID: 33561722.
- Hang Q, Zeng L, Wang L, Nie L, Yao F, Teng H, Deng Y, Yap S, Sun Y, Frank SJ, Chen J, Ma L. Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance. Nat Commun 12(1):4033, 2021. e-Pub 2021. PMID: 34188037.
- Ford JR, Rubin ML, Frank SJ, Ning J, Debnam JM, Bell D, El-Naggar A, Ferrarotto R, Esmaeli B. Prognostic factors for local recurrence and survival and impact of local treatments on survival in lacrimal gland carcinoma. Br J Ophthalmol 105(6):768-774, 2021. e-Pub 2020. PMID: 32680839.
- Awan MJ, Gittleman H, Barnholtz-Sloan J, Machtay M, Nguyen-Tan PF, Rosenthal DI, Schultz C, Huth BJ, Thorstad WL, Frank SJ, Kim H, Foote RL, Lango MN, Shenouda G, Suntharalingam M, Harris J, Zhang Q, Le QT, Yao M, NRG Oncology Group. Risk groups of laryngeal cancer treated with chemoradiation according to nomogram scores - A pooled analysis of RTOG 0129 and 0522. Oral Oncol 116:105241, 2021. e-Pub 2021. PMID: 33640577.
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- Hsu IC, Yamada Y, Assimos DG, D'Amico AV, Davis BJ, Frank SJ, Gottschalk AR, Gustafson GS, McLaughlin PW, Nguyen PL, Rosenthal SA, Taira AV, Vapiwala N, Merrick G. ACR Appropriateness Criteria high-dose-rate brachytherapy for prostate cancer. Brachytherapy 13(1):27-31, 2014. e-Pub 2013. PMID: 24368283.
- Takiar V, Pugh TJ, Swanson D, Kudchadker RJ, Bruno TL, McAvoy S, Mahmood U, Frank SJ. MRI-based sector analysis enhances prostate palladium-103 brachytherapy quality assurance in a Phase II prospective trial of men with intermediate-risk localized prostate cancer. Brachytherapy 13(1):68-74, 2014. e-Pub 2013. PMID: 23669149.
- Pugh TJ, Munsell MF, Choi S, Nguyen QN, Mathai B, Zhu XR, Sahoo N, Gillin M, Johnson JL, Amos RA, Dong L, Mahmood U, Kuban DA, Frank SJ, Hoffman KE, McGuire SE, Lee AK. Quality of Life and Toxicity From Passively Scattered and Spot-Scanning Proton Beam Therapy for Localized Prostate Cancer. Int J Radiat Oncol Biol Phys 87(5):946-53, 2013. e-Pub 2013. PMID: 24139077.
- Cerne JZ, McGuire SE, Grant SR, Munsell MF, Lee AK, Kudchadker RJ, Choi SL, Mahmood U, Hoffman KE, Pugh TJ, Frank SJ, Kuban DA. Factors associated with improved biochemical response to neoadjuvant androgen deprivation therapy before definitive radiation therapy in prostate cancer patients. Prostate Cancer Prostatic Dis 16(4):346-51, 2013. e-Pub 2013. PMID: 23939133.
- El-Sawy T, Frank SJ, Hanna E, Sniegowski M, Lai SY, Nasser QJ, Myers J, Esmaeli B. Multidisciplinary Management of Lacrimal Sac/Nasolacrimal Duct Carcinomas. Ophthal Plast Reconstr Surg 29(6):454-7, 2013. PMID: 24195987.
- Bui M, Frank SJ, Nasser QJ, El-Sawy T, McLemore MS, Morrison WH, Esmaeli B. Multidisciplinary management of primary adenoid cystic carcinoma of the eyelid with perineural invasion. Ophthal Plast Reconstr Surg 29(6):e143-6, 2013. e-Pub 2013. PMID: 23446295.
- Gunn GB, Mendoza TR, Fuller CD, Gning I, Frank SJ, Beadle BM, Hanna EY, Lu C, Cleeland CS, Rosenthal DI. High Symptom Burden Prior to Radiation Therapy for Head and Neck Cancer: A Patient-Reported Outcomes Study. Head Neck 35(10):1490-8, 2013. e-Pub 2012. PMID: 23169304.
- Brown AP, Pugh TJ, Swanson DA, Kudchadker RJ, Bruno TL, Christensen EN, Van Vulpen M, Frank SJ*. Improving prostate brachytherapy quality assurance with MRI-CT fusion-based sector analysis in a Phase II prospective trial of men with intermediate-risk prostate cancer. Brachytherapy 12(5):401-7, 2013. e-Pub 2013. PMID: 23380383.
- Nguyen QN, Levy LB, Lee AK, Choi SS, Frank SJ, Pugh TJ, McGuire S, Hoffman K, Kuban DA. Long-term outcomes for men with high-risk prostate cancer treated definitively with external beam radiotherapy with or without androgen deprivation. Cancer 119(18):3265-71, 2013. e-Pub 2013. PMID: 23798338.
- Gunn GB, Debnam JM, Fuller CD, Morrison WH, Frank SJ, Beadle BM, Sturgis EM, Glisson BS, Phan J, Rosenthal DI, Garden AS. The impact of radiographic retropharyngeal adenopathy in oropharyngeal cancer. Cancer 119(17):3162-9, 2013. e-Pub 2013. PMID: 23733178.
- Quan EM, Liu W, Wu R, Li Y, Frank SJ, Zhang X, Zhu XR, Mohan R. Preliminary evaluation of multi-field and single-field optimization for the treatment planning of spot-scanning proton therapy of head and neck cancer. Med Phys 40(8):081709, 2013. PMID: 23927306.
- Gillenwater AM, Frank SJ, Fatani H, El-Naggar AK. Primary intestinal-like adenocarcinoma of major salivary glands: Two instances of previously undocumented phenotype. Head Neck 35(8):E234-6, 2013. e-Pub 2012. PMID: 23108630.
- Register SP, Kudchadker RJ, Levy LB, Swanson DA, Pugh TJ, Bruno TL, Frank SJ*. An MRI-based dose-response analysis of urinary sphincter dose and urinary morbidity after brachytherapy for prostate cancer in a Phase II prospective trial. Brachytherapy 12(3):210-6, 2013. e-Pub 2013. PMID: 23466360.
- Boonsirikamchai P, Choi S, Frank SJ, Ma J, Elsayes KM, Kaur H, Choi H. MR Imaging of Prostate Cancer in Radiation Oncology: What Radiologists Need to Know. Radiographics 33(3):741-61, 2013. PMID: 23674772.
- Cheung JP, Park PC, Court LE, Zhu XR, Kudchadker RJ, Frank SJ, Dong L. A novel dose-based positioning method for CT image-guided proton therapy. Med Phys 40(5):051714, 2013. PMID: 23635262.
- Liu W, Frank SJ, Li X, Li Y, Park PC, Dong L, Zhu XR, Mohan R. Effectiveness of robust optimization in intensity-modulated proton therapy planning for head and neck cancers. Med Phys 40(5):051711, 2013. PMID: 23635259.
- Yang J, Beadle BM, Garden AS, Gunn B, Rosenthal DI, Ang K, Frank SJ, Williamson R, Balter P, Court L, Dong L. Auto-segmentation of low-risk clinical target volume for head and neck radiation therapy. Pract Radiat Oncol 4(1):31-37. e-Pub 2013.
- Pugh TJ, Frank SJ, Achim M, Kuban DA, Lee AK, Hoffman KE, McGuire SE, Swanson DA, Kudchadker R, Davis JW. Endorectal magnetic resonance imaging for predicting pathologic T3 disease in Gleason Score 7 prostate cancer: Implications for prostate brachytherapy. Brachytherapy 12(3):204-9, 2013. e-Pub 2012. PMID: 22673704.
- Frank SJ, Johansen MJ, Martirosyan KS, Gagea M, Van Pelt CS, Borne A, Carmazzi Y, Madden T. A biodistribution and toxicity study of cobalt dichloride-n-acetyl cysteine in an implantable MRI marker for prostate cancer treatment. Int J Radiat Oncol Biol Phys 85(4):1024-1030, 2013. e-Pub 2012. PMID: 23092727.
- Garden AS, Dong L, Morrison WH, Stugis EM, Glisson BS, Frank SJ, Beadle BM, Gunn GB, Schwartz DL, Kies MS, Weber RS, Ang KK, Rosenthal DI. Patterns of disease recurrence following treatment of oropharyngeal cancer with intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys 85(4):941-947, 2013. e-Pub 2012. PMID: 22975604.
- Castle KO, Hoffman KE, Levy LB, Lee AK, Choi S, Nguyen QN, Frank SJ, Pugh TJ, McGuire SE, Kuban DA. Is androgen deprivation therapy necessary in all intermediate-risk prostate cancer patients treated in the dose escalation era?. Int J Radiat Oncol Biol Phys 85(3):693-699, 2013. e-Pub 2012. PMID: 22836052.
- Kandula S, Zhu X, Garden AS, Gillin M, Rosenthal DI, Ang KK, Mohan R, Amin MV, Garcia JA, Wu R, Sahoo N, Frank SJ. Spot-scanning beam proton therapy vs intensity-modulated radiation therapy for ipsilateral head and neck malignancies: A treatment planning comparison. Med Dosim 38(4):390-4, 2013. e-Pub 2013. PMID: 23916884.
- Garden AS, Kies MS, Morrison WH, Weber RS, Frank SJ, Glisson BS, Gunn GB, Beadle BM, Ang KK, Rosenthal DI, Sturgis EM. Outcomes and patterns of care of patients with locally advanced oropharyngeal carcinoma treated in the early 21st century. Radiat Oncol 8(1):21, 2013. e-Pub 2013. PMID: 23360540.
- McGuire SE, Lee AK, Cerne JZ, Munsell MF, Levy LB, Kudchadker RJ, Choi SL, Nguyen QN, Hoffman KE, Pugh TJ, Frank SJ, Corn PG, Logothetis CJ, Kuban DA. PSA Response to Neoadjuvant Androgen Deprivation Therapy Is a Strong Independent Predictor of Survival in High-Risk Prostate Cancer in the Dose-Escalated Radiation Therapy Era. Int J Radiat Oncol Biol Phys 85(1):e39-46, 2013. e-Pub 2012. PMID: 23102837.
- Albert JM, Swanson DA, Pugh TJ, Zhang M, Bruno TL, Kudchadker RJ, Frank SJ*. Magnetic resonance imaging-based treatment planning for prostate brachytherapy. Brachytherapy 12(1):30-7, 2013. e-Pub 2012. PMID: 22727474.
- Fisher CM, Troncoso P, Swanson DA, Munsell MF, Kuban DA, Lee AK, Yeh SF, Frank SJ*. Knife or Needles? A Cohort Analysis of Outcomes after Radical Prostatectomy or Brachytherapy for Men with Low- or Intermediate-Risk Adenocarcinoma of the Prostate. Brachytherapy 11(6):429-34, 2012. e-Pub 2012. PMID: 22727472.
- Bian SX, Kuban DA, Levy LB, Oh J, Castle KO, Pugh TJ, Choi S, McGuire SE, Nguyen QN, Frank SJ, Nguyen PL, Lee AK, Hoffman KE. Addition of short-term androgen deprivation therapy to dose-escalated radiation therapy improves failure-free survival for select men with intermediate-risk prostate cancer. Ann Oncol 23(9):2346-52, 2012. e-Pub 2012. PMID: 22357249.
- Kim MM, Hoffman KE, Levy LB, Frank SJ, Pugh TJ, Choi S, Nguyen QN, McGuire SE, Lee AK, Kuban DA. Prostate cancer-specific mortality after definitive radiation therapy: Who dies of disease?. Eur J Cancer 48(11):1664-71, 2012. e-Pub 2012. PMID: 22336663.
- Vassiliev ON, Kudchadker RJ, Kuban DA, Frank SJ, Choi S, Nguyen Q, Lee AK. Dosimetric impact of fiducial markers in patients undergoing photon beam radiation therapy. Phys Med 28(3):240-4, 2012. e-Pub 2011. PMID: 21875820.
- Sharp HJ, Swanson DA, Pugh TJ, Zhang M, Phan J, Kudchadker R, Bruno TL, Kuban DA, Lee AK, Choi S, Nguyen QN, Hoffman KE, McGuire SE, Frank SJ*. Screening colonoscopy before prostate cancer treatment can detect colorectal cancers in asymptomatic patients and reduce the rate of rectal complications following brachytherapy. Pract Radiat Oncol 3(E):7-13. e-Pub 2012. PMID: 22727474.
- Chronowski GM, Garden AS, Morrison WH, Frank SJ, Schwartz DL, Shah SJ, Beadle BM, Gunn GB, Kupferman ME, Ang KK, Rosenthal DI. Unilateral Radiotherapy for the Treatment of Tonsil Cancer. Int J Radiat Oncol Biol Phys 83(1):204-9, 2012. e-Pub 2011. PMID: 22019242.
- Whaley JT, Levy LB, Swanson DA, Pugh TJ, Kudchadker RJ, Bruno TL, Frank SJ*. Sexual function and the use of medical devices or drugs to optimize potency after prostate brachytherapy. Int J Radiat Oncol Biol Phys 82(5):e765-71, 2012. e-Pub 2012. PMID: 22300559.
- Abdel-Wahab M, Mahmoud O, Merrick G, Hsu IC, Arterbery VE, Ciezki JP, Frank SJ, Mohler JL, Moran BJ, Rosenthal SA, Rossi CJ, Yamada Y. ACR Appropriateness Criteria(®) External-Beam Radiation Therapy Treatment Planning for Clinically Localized Prostate Cancer. J Am Coll Radiol 9(4):233-8, 2012. PMID: 22469373.
- Hinnen KA, Monninkhof EM, Battermann JJ, Van Roermund JG, Frank SJ, Van Vulpen M. Prostate Specific Antigen Bounce Is Related to Overall Survival in Prostate Brachytherapy. Int J Radiat Oncol Biol Phys 82(2):883-8, 2012. e-Pub 2011. PMID: 21300477.
- Grimm P, Billiet I, Bostwick D, Dicker AP, Frank SJ, Immerzeel J, Keyes M, Kupelian P, Lee WR, Machtens S, Mayadev J, Moran BJ, Merrick G, Millar J, Roach M, Stock R, Shinohara K, Scholz M, Weber E, Zietman A, Zelefsky M, Wong J, Wentworth S, Vera R, Langley S. Comparative analysis of prostate-specific antigen free survival outcomes for patients with low-, intermediate- and high-risk prostate cancer treatment by radical therapy. Results from the Prostate Cancer Results Study Group. BJU International 109 Suppl 1:22-9, 2012. PMID: 22239226.
- Frank SJ, Levy LB, van Vulpen M, Crook J, Sylvester J, Grimm P, Pugh TJ, Swanson DA. Outcomes after prostate brachytherapy are even better than predicted. Cancer 118(3):839-47, 2012. e-Pub 2011. PMID: 21751187.
- Kim MM, Hoffman KE, Levy LB, Frank SJ, Pugh TJ, Choi S, Nguyen QN, McGuire SE, Lee AK, Kuban DA. Improvement in prostate cancer survival over time: A 20-year analysis. Cancer J 18(1):1-8, 2012. PMID: 22290249.
- Kudchadker RJ, Pugh TJ, Swanson DA, Bruno TL, Bolukbasi Y, Frank SJ*. Preoperative treatment planning with intraoperative optimization can achieve consistent high-quality implants in prostate brachytherapy. Med Dosim 37(4):387-90, 2012. e-Pub 2012. PMID: 22560295.
- Moran BJ, Derose P, Hsu IC, Abdel-Wahab M, Arterbery VE, Ciezki JP, Frank SJ, Mohler JL, Rosenthal SA, Rossi CJ, Yamada Y, Merrick GS, Expert Panel on Radiation Oncology-Prostate. ACR Appropriateness Criteria® Definitive External Beam Irradiation in Stage T1 and T2 Prostate Cancer. Am J Clin Oncol 34(6):636-647, 2011. PMID: 22101389.
- Expert Panel on Radiation Oncology-Prostate, Frank SJ, Arterbery VE, Hsu IC, Abdel-Wahab M, Ciezki JP, Hahn NM, Mohler JL, Moran BJ, Rosenthal SA, Rossi CJ, Yamada Y, Merrick G. American College of Radiology Appropriateness Criteria Permanent Source Brachytherapy for Prostate Cancer. Brachytherapy 10(5):357-62, 2011. e-Pub 2011. PMID: 21497562.
- Vassiliev ON, Kudchadker RJ, Swanson DA, Bruno TL, Van Vulpen M, Frank SJ*. Displacement of periurethral stranded seeds and its dosimetric consequences in prostate brachytherapy. Brachytherapy 10(5):401-8, 2011. e-Pub 2011. PMID: 21306959.
- Shirvani SM, Kudchadker RJ, Bruno TL, Likhacheva A, Swanson DA, Frank SJ*. Impact Of Urinary Catheterization On Dosimetry After Prostate Implant Brachytherapy With Palladium-103 Or Iodine-125. Brachytherapy 10(4):269-74, 2011. e-Pub 2011. PMID: 21296031.
- Skinner HD, Garden AS, Rosenthal DI, Ang KK, Morrison WH, Esmaeli B, Pinnix CC, Frank SJ*. Outcomes of malignant tumors of the lacrimal apparatus: The University of Texas MD Anderson Cancer Center experience. Cancer 117(12):2801-10, 2011. e-Pub 2011. PMID: 21656758.
- Kuban DA, Levy LB, Cheung MR, Lee AK, Choi S, Frank S, Pollack A. Long-term Failure Patterns and Survival in a Randomized Dose-Escalation Trial for Prostate Cancer. Who Dies of Disease?. Int J Radiat Oncol Biol Phys 79(5):1310-7, 2011. e-Pub 2010. PMID: 20493642.
- Rossi CJ, Joe Hsu IC, Abdel-Wahab M, Arterbery VE, Ciezki JP, Frank SJ, Hahn NM, Moran BJ, Rosenthal SA, Merrick G. ACR Appropriateness Criteria® Postradical Prostatectomy Irradiation in Prostate Cancer. Am J Clin Oncol 34(1):92-98, 2011. PMID: 21270599.
- Samuelian JM, Swanson DA, Kudchadker RJ, Pugh TJ, Kuban DA, Lee AK, Choi S, Nguyen QN, Bruno TL, Frank SJ*. Long-term Tumor Control After Brachytherapy for Cancer at the Base of the Prostate. J Contemp Brachytherapy 3(4):183-187, 2011.
- Sharp HJ, Swanson DA, Patel H, Gorbatiy V, Frenzel JC, Frank SJ*. Subacute penile numbness after brachytherapy for prostate cancer. Brachytherapy 10(1):64-7, 2011. e-Pub 2010. PMID: 20685173.
- Frank SJ, Tailor RC, Kudchadker RJ, Martirosyan KS, Stafford RJ, Elliott AM, Swanson DA, Sing D, Choi J, Mourtada F, Ibbott GS. Anisotropy characterization of I-125 seed with attached encapsulated cobalt chloride complex contrast agent markers for MRI-based prostate brachytherapy. Med Dosim 36(2):200-5, 2011. e-Pub 2010. PMID: 20537886.
- Savar A, Oellers P, Myers J, Prieto VG, Torres-Cabala C, Frank SJ, Ivan D, Esmaeli B. Positive Sentinel Node in Sebaceous Carcinoma of the Eyelid. Ophthal Plast Reconstr Surg 27(1):e4-6, 2011. e-Pub 2010. PMID: 20940661.
- Skinner HD, Sturgis EM, Klopp AH, Ang KK, Rosenthal DI, Garden AS, Morrison WH, Gunn GB, Frank SJ, Beadle BM. Characteristics and Clinical Outcomes of Patients with Multiple Potentially HPV-Related Malignancies. Int J Radiat Oncol Biol Phys 78(3, Suppl):S441-S442, 2010.
- Frank SJ, Rosenthal DI, Petsuksiri J, Ang KK, Morrison WH, Weber RS, Glisson BS, Chao KS, Schwartz DL, Chronowski GM, El-Naggar AK, Garden AS. Intensity-Modulated Radiotherapy for Cervical Node Squamous Cell Carcinoma Metastases from Unknown Head-and-Neck Primary Site: MD Anderson Cancer Center Outcomes and Patterns of Failure. Int J Radiat Oncol Biol Phys 78(4):1005-10, 2010. e-Pub 2010. PMID: 20207504.
- Moeller BJ, Rana V, Cannon BA, Williams MD, Sturgis EM, Ginsberg LE, Macapinlac HA, Lee JJ, Ang KK, Chao KS, Chronowski GM, Frank SJ, Morrison WH, Rosenthal DI, Weber RS, Garden AS, Lippman SM, Schwartz DL. Prospective Imaging Assessment of Mortality Risk After Head-and-Neck Radiotherapy. Int J Radiat Oncol Biol Phys 78(3):667-74, 2010. e-Pub 2010. PMID: 20171802.
- Roeloffzen EM, Hinnen KA, Battermann JJ, Monninkhof EM, Van Roermund JG, Van Gellekom MP, Frank SJ, Van Vulpen M. The Impact of Acute Urinary Retention After Iodine-125 Prostate Brachytherapy on Health-Related Quality of Life. Int J Radiat Oncol Biol Phys 77(5):1322-8, 2010. e-Pub 2009. PMID: 19939578.
- Rosenthal DI, Fuller CD, Barker JL, Mason B, Garcia JA, Lewin JS, Holsinger FC, Stasney CR, Frank SJ, Schwartz DL, Morrison WH, Garden AS, Ang KK. Simple Carotid-Sparing Intensity-Modulated Radiotherapy Technique and Preliminary Experience for T1-2 Glottic Cancer. Int J Radiat Oncol Biol Phys 77(2):455-61, 2010. e-Pub 2009. PMID: 19679406.
- Hinnen KA, Battermann JJ, Van Roermund JG, Moerland MA, Jürgenliemk-Schulz IM, Frank SJ, Van Vulpen M. Long-Term Biochemical and Survival Outcome of 921 Patients Treated with I-125 Permanent Prostate Brachytherapy. Int J Radiat Oncol Biol Phys 76(5):1433-8, 2010. e-Pub 2009. PMID: 19540075.
- Frank SJ, Kudchadker RJ, Kuban DA, de Crevoisier R, Lee AK, Cheung RM, Choi S, Tucker SL, Dong L. A Volumetric Trend Analysis of the Prostate and Seminal Vesicles during a Course of Intensity-Modulated Radiation Therapy. Am J Clin Oncol 33(2):173-5, 2010. PMID: 20010077.
- Roeloffzen EM, Lips IM, van Gellekom MP, van Roermund J, Frank SJ, Battermann JJ, van Vulpen M. Health-Related Quality of Life up to Six Years After (125)I Brachytherapy for early-stage Prostate Cancer. Int J Radiat Oncol Biol Phys 76(4):1054-60, 2010. e-Pub 2010. PMID: 20097486.
- Anderson JF, Swanson DA, Levy LB, Kuban DA, Lee AK, Kudchadker R, Phan J, Bruno T, Frank SJ*. Urinary Side Effects and Complications After Permanent Prostate Brachytherapy: The MD Anderson Cancer Center Experience. Urology 74(3):601-5, 2009. e-Pub 2009. PMID: 19589580.
- Peterson S, Polf J, Ciangaru G, Frank SJ, Bues M, Smith A. Variations in Proton Scanned Beam Dose Delivery Due to Uncertainties in Magnetic Beam Steering. Med Phys 38(8):3693-3702, 2009. PMID: 19746802.
- Phan J, Swanson DA, Levy LB, Kudchadker RJ, Bruno TL, Frank SJ*. Late Rectal Complications after prostate brachytherapy for localized prostate cancer: Incidence and Management. Cancer 115(9):1827-1839, 2009. PMID: 19248043.
- Moeller B, Rana V, Cannon B, Williams M, Sturgis E, Ginsberg L, Macapinlac H, Lee J, Ang KK, Chao KSC, Chronowski G, Frank SJ, Morrison W, Rosenthal D, Weber R, Garden A, Lippman S, Schwartz D. Prospective risk-adjusted [18F]Fluorodeoxyglucose positron emission tomography and computed tomography assessment of radiation response in head and neck cancer. J Clin Oncol 27(15):2509-2515, 2009. e-Pub 2009. PMID: 19332725.
- Frank SJ, Levy LB, Kuban DA, Lee AK, Kudchadker RJ, Bruno TL, van Vulpen M, Swanson DA. Prostogram predicted brachytherapy outcomes are not universally accurate: An analysis based on the MD Anderson Cancer Center experience with (125)iodine brachytherapy. J Urol 181(4):1658-63; discussion 1663-4. e-Pub 2009. PMID: 19233434.
- Hsu A, Frank SJ, Ballo MT, Garden AS, Morrison WH, Rosenthal DI, Hatef E, Esmaeli B. Post-Operative Adjuvant External-beam Radiation Therapy for Cancers of the Eyelid and Conjunctiva. Ophthal Plast Reconstr Surg 24(6):444-449, 2008. PMID: 19033839.
- McGuire SE, Frank SJ*, Eifel PJ (*corresponding author). Treatment of recurrent vaginal melanoma with external beam radiation therapy and palladium-103 brachytherapy. Brachytherapy 7(4):359-63, 2008. e-Pub 2008. PMID: 18778972.
- Kudchadker RJ, Swanson DA, Kuban DA, Lee AK, Bruno TL, Frank SJ*. Is a Loose-Seed Nomogram Still Valid for Prostate Brachytherapy in a Stranded-Seed Era?. Int J Radiat Oncol Biol Phys 72(2):623-7, 2008. e-Pub 2008.
- Frank SJ, Dong L, Kudchadker RJ, de Crevoisier R, Lee AK, Cheung R, Choi S, O'Daniel J, Tucker SL, Wang H, Kuban DA. Quantification of prostate and seminal vesicle interfraction variation during IMRT. Int J Radiat Oncol Biol Phys 71(3):813-20, 2008. e-Pub 2008. PMID: 18207664.
- Frank SJ, Stafford RJ, Bankson JA, Li C, Swanson DA, Kudchadker RJ, Martirosyan KS. A Novel MRI Marker for Prostate Brachytherapy. Int J Radiat Oncol Biol Phys 71(1):5-8, 2008. PMID: 18406882.
- Petsuksiri J, Frank SJ*, Garden AS, Ang KK, Morrison WH, Chao KS, Rosenthal DI, Schwartz DL, Ahamad A, Esmaeli B (*corresponding author). Outcomes after radiotherapy for squamous cell carcinoma of the eyelid. Cancer 112(1):111-8, 2008. e-Pub 2007. PMID: 17963262.
- Chao KS, Bhide S, Chen H, Asper J, Bush S, Franklin G, Kavadi V, Liengswangwong V, Gordon W, Raben A, Strasser J, Kaproswki C, Frank SJ, Chronowski G, Ahamad A, Malyapa R, Zhang L, Dong L. Reduce in variation and improve efficiency of target volume delineation by a computer-assisted system using a deformable image registration approach. Int J Radiat Oncol Biol Phys 68(5):1512-21, 2007. PMID: 17674982.
- Frank SJ, Pisters LL, Davis J, Lee AK, Bassett R, Kuban DA. An assessment of quality of life following radical prostatectomy, high dose external beam radiation therapy and brachytherapy iodine implantation as monotherapies for localized prostate cancer. J Urol 177(6):2151-6, 2007. PMID: 17509305.
- Frank SJ, Deavers MT, Jhingran A, Bodurka DC, Eifel PJ. Primary adenocarcinoma of the vagina not associated with diethylstilbestrol (DES) exposure. Gynecol Oncol 105(2):470-4, 2007. e-Pub 2007. PMID: 17292459.
- Cheung MR, Tucker SL, Dong L, de Crevoisier R, Lee AK, Frank S, Kudchadker RJ, Thames H, Mohan R, Kuban D. Investigation of bladder dose and volume factors influencing late urinary toxicity after external beam radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys 67:1059-65, 2007. PMID: 17241755.
- Frank SJ, Grimm PD, Sylvester JE, Merrick GS, Davis BJ, Zietman A, Moran BJ, Beyer DC, Roach M, Clarke DH, Stock RG, Lee RW, Michalski JM, Wallner KE, Hurwitz M, Potters L, Kuban DA, Prestidge BR, Vera R, Hathaway S, Blasko JC. Interstitial Implant Alone or in Combination with External Beam Radiation Therapy for Intermediate-Risk Prostate Cancer: A Survey of Practice Patterns in the United States. Brachytherapy 6(1):2-8, 2007. PMID: 17284379.
- Patel S, Jagsi R, Wilson J, Frank S, Thakkar VV, Hansen EK. Results of the 2004 Association of Residents in Radiation Oncology (ARRO) Survey. Int J Radiat Oncol Biol Phys 66(4):1199-203, 2006. PMID: 16979833.
- Lee AK, Frank SJ. Update on radiation therapy in prostate cancer. Hematol Oncol Clin North Am 20(4):857-878, 2006. PMID: 16861119.
- Frank SJ, Chao KS, Schwartz DL, Weber RS, Apisarnthanarax S, Macapinlac HA. Technology Insight: PET and PET/CT in head and neck tumor staging and radiation therapy planning. Nat Clin Pract Oncol 2(10):526-533, 2005. PMID: 16205772.
- Callaghan EB, Padgett AV, Frank SJ. Self-Referral: What Residents Need to Know?. J Am Coll Radiol 2(5):452454, 2005. PMID: 17411855.
- Frank SJ, Jhingran A, Levenback C, Eifel PJ. Definitive treatment of invasive squamous cell carcinoma of the vagina with radiation therapy. Int J Radiat Oncol Biol Phys 62(1):138-147, 2005. PMID: 15850914.
- Jagsi R, Buck DA, Singh AK, Engleman M, Thakkar V, Frank SJ, Flynn D. Results of the 2003 Association of Residents in Radiation Oncology (ARRO) surveys of residents and chief residents in the United States. Int J Radiat Oncol Biol Phys 61(3):642-648, 2005. PMID: 15708241.
- Frank SJ, McNeese MD, Strom EA, Perkins G, Salehpour M, Schechter N, Buchholz TA. Advances in radiation treatments of breast cancer. Clin Breast Cancer 4(6):401-406, 2004. PMID: 15023240.
- Brooks C, Starkschall G, Famiglietti R, Cox J, Frank SJ, Komaki R, Liao Z, Stevens C, Forster K. Heterogeneous planning for homogeneous protocols. Med Dosim 29(2):80-84, 2004. PMID: 15191752.
- Frank SJ, Forster KM, Stevens CW, Cox JD, Komaki R, Liao Z, Tucker S, Wang X, Steadham RE, Brooks C, Starkschall G. Treatment planning for lung cancer: traditional homogeneous point-dose prescription compared with heterogeneity-corrected dose-volume prescription. Int J Radiat Oncol Biol Phys 56(5):1308-1318, 2003. PMID: 12873675.
Invited Articles
- Holliday EB, Frank SJ*. Current applications of proton beam radiation for the treatment of head and neck tumors. Otorinolaringo 64:1-11, 2014. e-Pub 2014.
- Gunn GB, Frank SJ*. Advances in radiation oncology for the management of oropharyngeal tumors. Otolaryngol Clin North Am 46(4):629-43, 2013. e-Pub 2013. PMID: 23910474.
- Eberhardt SC, Carter S, Casalino DD, Merrick G, Frank SJ, Gottschalk AR, Leyendecker JR, Nguyen PL, Oto A, Porter C, Remer EM, Rosenthal SA. ACR Appropriateness Criteria prostate cancer--pretreatment detection, staging and surveillance. J Am Coll Radiol 10(2):83-92, 2013. PMID: 23374687.
- Pugh TJ, Frank SJ*. Quality Of Life Issues In The Radiotherapeutic Management Of Localized Prostate Cancer. Radiation Medicine Rounds 2(1), 2011.
Other Articles
- Kaplan RS, Blackstone RP, Haas DA, Thaker NG, Frank SJ* Measuring and Communicating Health Care Value with Charts. Harvard Business Review.
- Ciezki JP, Hsu IC, Abdel-Wahab M, Arterbery VE, Frank SJ, Mohler JL, Moran BJ, Rosenthal SA, Rossi CJ, Yamada Y, Merrick G, American College of Radiology Appropriateness Criteria American College of Radiology Appropriateness Criteria(®) - Locally Advanced (High-risk) Prostate Cancer. Clin Oncol (R Coll Radiol) 24(1):43-51, 2012. PMID: 21875782.
- Martirosyan KS, Stafford RJ, Elliott AM, Frank SJ* PMMA/SWCNTs Composites for Prostate Brachytherapy MRI Contrast Agent Markers. Technical Proceedings of the 2009 NSTI Nanotechnology Conference and Expo 2:44-47, 2009.
- Frank SJ, Curley MD, Ryder SJ A biomedical review of the U.S. Navy submarine escape system. Rep US Nav Submar Med Cent, 1997.
Editorials
- Frank SJ*. Bending the slope of the brachytherapy curve: Magnetic resonance imaging-assisted radiosurgery for the treatment of prostate cancer. Brachytherapy 16(4):657-658, 2017.
- Frank SJ*. Intensity-Modulated Proton Therapy for Head and Neck Tumors: Gilding the Lily or Holy Grail?. Int J Radiat Oncol Biol Phys 95(1):37-9, 2016. PMID: 27084621.
- Lai SY, Fuller CD, Bhattacharya PK, Frank SJ*. Metabolic Imaging as a Biomarker of Early Radiation Response in Tumors. Clin Cancer Res 21(22):4996-8, 2015. PMID: 26232369.
- Petereit DG, Frank SJ, Viswanathan AN, Erickson B, Eifel P, Nguyen PL, Wazer DE. Where Have You Gone Brachytherapy?. J Clin Oncol 33(9):980-2, 2015. PMID: 25667278.
- Frank SJ. Oncology scan-demonstrating technology and measuring outcomes in head and neck cancer. Int J Radiat Oncol Biol Phys 88(4):759-60, 2014. PMID: 24606844.
- Frank SJ, Yang T, Chao KSC. Role of PET-CT Fusion in Head and Neck Cancer. Oncology 2(19):246-249, 2005.
- Frank SJ, Buchholz TA. Diminished Survival in Patients with Inner Versus Outer Quadrant Breast Cancers. Women's Oncology Review 3:157-158, 2003.
Abstracts
- Sanders J, Mok H, Hanania A, Venkatesan A, Tang C, Bruno T, Thames H, Kudchadker R, Frank SJ*. Assessing the variability of contours performed by DL algorithms in prostate MRI. Int J Radiat Oncol Biol Phys, 2021.
- Sanders J, Mok H, Levitt C, Tang C, Kudchadker R, Venkatesan A, Bruno T, Starks C, Santiago E, Cunningham M, Wells M, Weaver C, Frank SJ*. Autosegmentation in the clinic: Initial experiences with LDR prostate cancer patients from two MRI-based practices. Int J Radiat Oncol Biol Phys, 2021.
- Sanders J, Mok H, Hanania A, Venkatesan A, Tang C, Bruno T, Thames H, Kudchadker R, Frank SJ*. Interobserver variability of target and OAR delineation in MRI-based prostate brachytherapy across two anatomical pulse sequences. Int J Radiat Oncol Biol Phys, 2021.
- Sanders J, Mok H, Tang C, Hanania A, Venkatesan A, Bruno T, Kudchadker R, Thames H, Frank SJ*. Benchmarking automatic segmentation algorithms against human interobserver variability of prostate and organs at risk delineation on prostate MRI. Int J Radiat Oncol Biol Phys, 2021.
- Sanders J, Mok H, Hanania A, Venkatesan A, Tang C, Bruno T, Thames H, Kudchadker R, Frank SJ*. Computer vision exhibits entropy similar to prostate cancer physicians. Int J Radiat Oncol Biol Phys, 2021.
- Barbon CE, Peterson CB, Dirba DD, Gunn GB, Frank SJ, Ferrarotto R, Johnson FM, Hessel AC, Goepfert RP, Gross ND, Hutcheson KA. Comparison of Prospective, Longitudinal Swallowing Function after Primary Intensity-Modulated Proton Therapy (IMPT) or Transoral Robotic Surgery (TORS) for Oropharyngeal Squamous Cell Carcinoma. Int J Radiat Oncol Biol Phys 108(3):S160-S160, 2020.
- Wang L, Cao J, Liu Z, Lin E, Lu X, Li Y, Chen M, Kerr M, Wang X, Jiang B, Poenisch F, Yang M, Gautam AS, WU RY, Wang X, Zhang X, Swain J, Sahoo N, Zhu XR, Frank SJ*. Modulation Effect of CHK-1/-2 Inhibitor on Preclinical Head and Neck Cancer In Vivo Tumor Response to Proton and X-ray Radiation Therapy. Int J Radiat Oncol Biol Phys 108(3):E564-E565, 2020.
- Sanders J, Frank S, Venkatesan A, Bathala T, Tang C, Kudchadker R, Bruno T, Pagel M, Ma J. OC-1034: Parallel imaging compressed sensing for prostate MRI without an endorectal coil: A prospective study. Radiother Oncol 152:S1088-S1089, 2020.
- Sanders J, Venkatesan A, Davis J, Kudchadker R, Tang C, Bruno T, Ma J, Frank SJ*. OC-1040: Computer-aided brachytherapy: Assisting the practice of prostate brachytherapy with machine learning. Radiother Oncol 152:S1093-S1093, 2020.
- Ng SP, Cardenas C, Bahig H, Elgohari B, Moreno A, Shah S, Garden A, Phan J, Gunn GB, Frank S, Rosenthal D, Morrison W, Wang J, Fuller C. PO-1691: Apparent diffusion coefficient changes in weekly MRI during radiotherapy in head and neck cancer. Radiother Oncol 152:S931-S931, 2020.
- Ng SP, Cardenas CE, Bahig H, Elgohari B, Wang J, Johnson JM, Moreno AC, Shah SJ, Garden AS, Phan J, Gunn GB, Frank SJ, Ding Y, Na L, Yuan Y, Urbauer D, Rosenthal DI, Morrison WH, MacManus MP, Fuller CD. Changes In Apparent Diffusion Coefficient (ADC) In Serial Weekly MRI During Radiotherapy In Patients With Head And Neck Cancer: Results From The PREDICT-HN Study. Int J Radiat Oncol Biol Phys 108(3):E790-E791, 2020.
- Lin SH, Lei X, Liao K, Shaaban S, Chen AB, Lee P, Koong AC, Frank SJ, Liao Z, Giordano S, Smith GL. Comparing Healthcare Utilization, Hospitalization, and Costs with Neoadjuvant Intensity-Modulated Radiation Therapy (IMRT) versus Proton Beam Therapy (PBT) for Esophageal Cancer. Int J Radiat Oncol Biol Phys 108(3):S45-S46, 2020.
- Kim M, Abu-Gheida I, Bathala T, Maldonado JA, Khan M, Anscher MS, Frank SJ, Choi S, Nguyen QN, Hoffman KE, McGuire SE, Kuban DA, Aparicio A, Chapin B, Tang C. Comparisons of Treatment Outcomes and Patterns of Lymph Node Involvement in T4 Prostate Cancer Patients. Int J Radiat Oncol Biol Phys 108(3):E912-E912, 2020.
- Engeseth GM, He R, Mirkovic D, Yepes P, Stokkevag CH, Pettersen HE, Wahid KA, Adair A, Wu R, Zhang X, Mohamed AA, Fuller CD, Frank S, Mohan R, Gunn GB. PD-0178: NTCP model development and comparison for brain image changes after IMPT for head and neck cancer. Radiother Oncol 152:S87-S87, 2020.
- Elhalawani H, Volpe S, Cardenas CE, Stieb S, Rock C, Lin T, Yang P, Wu H, Barua S, Zaveri J, Elgohari B, Abdallah LE, Jethanandani A, Mohamed AS, Court LE, Gunn GB, Rosenthal DI, Frank SJ*. Investigation of Longitudinal Dose-Weighted FDG-Positron Emission Tomography Metabolic Imaging Biomarkers (PET MIBs) of Radiation-Associated Dysphagia in OPC Cohort. Int J Radiat Oncol Biol Phys 108(3):E312-313, 2020.
- Dalwadi SM, Thames HD, Tang C, Crook JM, Sanders J, Blanchard P, Ciezki JP, Keyes M, Merrick GS, Catton CN, Razlee H, Stock RG, Sullivan F, Millar JL, Frank SJ*. Is The Phoenix Criterion Of Biochemical Failure (BF) In Men Treated With Low-Dose Rate Prostate Brachytherapy Appropriate?. Int J Radiat Oncol Biol Phys 108(3):E908-909, 2020.
- Chen M, Wang Z, Adair AH, Yepes P, Sun J, Jiang S, Xu C, Chen J, Gunn GB, Frank SJ, Nguyen QN, Chang JY, Liao Z, Sahoo N, Zhu XR, Zhang X. Have We Underestimated the Risk of Radiation-Induced Esophagitis in Non-Small Cell Lung Cancer Patients Receiving Proton Therapy Using Constant RBE?. Int J Radiat Oncol Biol Phys 108(3):E119-E120, 2020.
- Bronk JK, Augustyn A, Mohamed AS, Wang R, Frank SJ, Fuller CD, Garden AS, Moreno AC, Morrison WH, Phan J, Reddy J, Rosenthal DI, Zafereo M, Ferrarotto R, Cabanillas ME, Gunn GB. Patterns Of Loco-Regional Failure And Outcomes After Intensity Modulated Radiation Therapy For Unresectable Anaplastic Thyroid Cancer. Int J Radiat Oncol Biol Phys 108(3):E849-E850, 2020.
- Branco D, Kry S, Taylor P, Rong J, Zhang X, Peterson C, Frank S, Followill D. PO-1754: A stereoscopic CT artifact reduction method image quality comparison to current vendor solutions. Radiother Oncol 152:S975-S976, 2020.
- Branco D, Taylor P, Kry S, Zhang X, Rong J, Frank S, Followill D. PD-0184: Proton dosimetric comparison of CT metal artifact reduction techniques for head and neck patients. Radiother Oncol 152:S90-S91, 2020.
- Sosa A, Wang C, Nguyen T, Reddy J, Moreno A, Garden A, Rosenthal D, Frank SJ, Fuller C, Shah S, Morrison W, Gunn B, Su S, Phan J. Gamma Knife Boost for Head and Neck Cancers with Skull Base Extension: A Case Series. Int J Radiat Oncol Biol Phys 108(2):E49-E49, 2020.
- Pasalic D, Ludmir E, Thaker N, Gunn B, Hanna E, Su S, Ferrarotto R, Glisson B, Reddy J, Fuller C, Phan J, Rosenthal D, Morrison W, Garden A. Frank SJ*. Prospective Patient-Reported Outcomes, Physician-Assessed Toxicities, and Treatment Outcomes in Sinonasal Malignancies Following Proton Beam Therapy. Int J Radiat Oncol Biol Phys 108(2):E14-E15, 2020.
- Gunn Gb, Ferraroto R, Johnson FM, Bell D, Cardoso R, Johnson JM, Rubin ML, Yuan Y, Frank SJ, Fuller CD, Rosenthal DI, Kupferman ME, Goepfert R, Hessel AC, Hutcheson KA, Gross ND. Prospective, longitudinal digital activity monitoring before and after treatment of low-risk oropharyngeal squamous cell carcinoma: A feasibility study. Journal of Clinical Oncology 38(15), 2020.
- Hanania AN, Gunn GB, Rosenthal DI, Garden AS, Fuller CD, Phan J, Reddy JP, Moreno AC, Ausat N, Myers NJ, Ferrarotto R, Frank SJ*. Intensity Modulated Proton Therapy (IMPT) to the Parotid Gland: A Seven-Year Experience. Int J Radiat Oncol Biol Phys 106(5):1195-1196, 2020.
- Ferrarotto R, Mitani Y, Karpinets T, Frank SJ, Song X, Fan Y, Liu B, Bell D, Kupferman ME, Futreal PA, Zhang J, Heymach J, El-Naggar AK. Integrative proteomic and transcriptomic analysis define adenoid cystic carcinoma subgroups with distinct therapeutic targets. Int J Radiat Oncol Biol Phys 106(5):1190-1190, 2020.
- Stieb S, Perez-Martinez I, Rock S, Mohamed AS, Bajaj N, Deshpande TS, Garden AS, Reddy JP, Phan J, Morrison WH, Frank SJ, Rosenthal DI, Koay EJ, Fuller CD, Gunn GB. Late Oral Toxicity after Photon Radiotherapy for Oropharyngeal Cancer Patients with Tongue-Lateralizing and Tongue-Depressing Oral Stents. Int J Radiat Oncol Biol Phys 106(5):1202-1203, 2020.
- Phan J, Bagley A, Adam G, Frank SJ, Gunn GB, Rosenthal DI, Reddy J, Fuller CD, Morrison WH, Shah SJ, Moreno AC, Ferrarotta R, Sturgis EM, Gross ND. Reirradiation with SBRT, IMRT and Proton Therapy for Recurrent Oropharynx Squamous Cell Carcinoma: Efficacy and Toxicity Outcomes. Int J Radiat Oncol Biol Phys 106(5):1144-1144, 2020.
- Ausat N, Rosenthal DI, Gunn GB, Ye R, Garden AS, Morrison WH, Fuller CD, Phan J, Reddy JP, Moreno AC, Bahig H, Sturgis EM, Glisson BS, Frank SJ*. Outcomes following Proton Therapy for Squamous Cell Carcinoma of the Larynx. Int J Radiat Oncol Biol Phys 106(5):1213-1213, 2020.
- Crook JM, Tang C, Thames H, Blanchard P, Sanders J, Ciezki JP, Keyes M, Merrick GS, Catton CN, Raziee H, Stock R, Sullivan F, Anscher M, Frank SJ*. Validation of biochemical definition of cure after low-dose rate prostate brachytherapy. Journal of Clinical Oncology 38(6), 2020.
- Zhu XR, Gillin M, Li H, Li Y, Lii MF, Taylor MB, Zhang X, Poenisch F, Sahoo N, Frank SJ*. Towards an Efficient and Effective Patient Specific QA Program For IMPT. 51st Annual Meeting of Particle Therapy Co-Operative Group (PTCOG51). e-Pub 2015.
- Thaker NG, Frank SJ, Feeley TW. Comparative costs of proton and x-ray therapies for advanced head and neck cancer: Lessons from Time-driven Activity-based Costing. Commentary. Journal of Comparative Effectiveness Research. e-Pub 2015.
- Thaker, NG, Guzman AB, Feeley TW, Jones TM, Incalcaterra JR, Kolom C, Tatum LS, Walters RS, Cantor S, Rosenthal DI, Garden, AS, Gunn GB, Fuller, CS, Palmer MB, Frank SJ . Defining the Value of Proton Therapy in an Evolving Healthcare System Using. Oncology Payers, 2014.
- Thaker NG, Kudchadker RJ, Frank SJ. A Phantom-Based Simulator Approach to Improving the Quality of Prostate Brachytherapy Training. American Radium Society’s 96th Annual Meeting, 2014.
- Melhus CS, Mikell JK, Frank SJ, Mourtada F, Rivard MJ. Dosimetric influence of seed spacers and end-weld thickness for permanent prostate brachytherapy. Brachytherapy 13(3), 2013.
- Liu W, Frank SJ, Li X, Li Y, Zhu XR, Mohan R. PTV-based IMPT optimization incorporating planning risk volumes vs robust optimization. Med Phys 40(2):021709, 2013. PMID: 23387732.
- Frank SJ, Rosenthal DI, Ang K, Sturgis EM, Chambers MS, Gunn GB, Hutcheson KA, Zhu XR, Palmer MB, Garden A. Gastrostomy tubes decrease by over 50% with intensity modulated proton therapy (IMPT) during the treatment of oropharyngeal cancer patients - A case-control study. Proceedings from ASTRO 2013, 2013.
- Hutcheson KA, Lewin JS, Garden AS, Rosenthal DI, Weber RS, William Jr WN, Gunn GB, Morrison WH, Fuller CD, Frank SJ. Early experience with IMPT for the treatment of oropharyngeal tumors: Acute toxicities and swallowing-related outcomes, 2013.
- Frank SJ, Cox JD, Gillin M, Rosenthal DI, Garden AS, Ang K, Mohan R, Palmer MB, Amin M, Zhu XR. Intensity modulated proton therapy for head-and-neck cancer: The first clinical experience. Int J Radiat Oncol Biol Phys 84(3):S475-76, 2012.
- Pugh TJ, Choi S, Nguyen Q, De Gracia B, Munsell MF, Frank SJ, Kuban DA, Hoffman KE, McGuire SE, Lee AK. Quality of Life and Toxicity Between Passively Scattered and Spot-Scanning Proton Therapy for Prostate Cancer. Int J Radiat Oncol Biol Phys 84(3):S392-393, 2012.
- Chronowski GM, Garden AS, Morrison WH, Frank SJ, Schwartz DL, Shah SJ, Beadle BM, Brandon Gunn G, Kupferman ME, Ang KK, Rosenthal DI. Unilateral Radiotherapy for the Treatment of Tonsil Cancer. Int J Radiat Oncol Biol Phys. e-Pub 2011. PMID: 22019242.
- Poenisch F, Sahoo N, Taylor MB, Grosshans DR, Frank SJ, Lii M, Wu R, Zhang X, Gillin M, Zhu XR. Verification of Multi-field Optimized Proton Pencil Beam Treatment Plans. Int J Radiat Oncol Biol Phys 81(2):S879, 2011.
- Christensen EN, Pugh TJ, Munsell MF, Swanson DA, Kudchadker RJ, Bruno TL, Brown AP, Frank SJ. Sector Analysis of Prostate Brachytherapy Shows That Low Doses can Achieve an Undetectable PSA. Int J Radiat Oncol Biol Phys 81(2):S422, 2011.
- Brown AP, Pugh TJ, Swanson DA, Kudchadker RJ, Bruno TL, Christensen EN, Frank SJ. Improving Prostate Brachytherapy Quality Assurance with MRI-Based Sector Analysis in a Phase II Prospective Trial. Int J Radiat Oncol Biol Phys 81(2):S209, 2011.
- Nguyen Q, Crawford C, Palmer M, Zhu R, Choi S, Pugh T, Frank SJ, Hoffman K, Kuban DA, Lee AK. Utilizing A Multifield Optimization Intensity Modulated Proton Technique (MFO-IMPT) To Deliver A Simultaneous Integrated Boost (SIB) To The Dominant Intraprostatic Lesion For Localized Prostate Cancer. Int J Radiat Oncol Biol Phys 81(2):S876-S877, 2011.
- Beadle BM, Garden AS, Morrison WH, Rosenthal DI, Gunn GB, Frank SJ, Hessel AC, Ang KK. Outcomes and Risk Factors in Patients Treated with Surgery and Postoperative Radiation Therapy Alone: A Subset Update of a Randomized Trial. Int J Radiat Oncol Biol Phys 81(2):S104-S105, 2011.
- Rosenthal DI, Fuller CD, Holsinger F, Morrison W, Weber RS, Ang K, Frank SJ, A.S. Garden. Conditional Survival for Locally Advanced Larynx Cancer. Int J Radiat Oncol Biol Phys 81(2):S516, 2011.
- Castle KO, Hoffman KE, Levy LB, Lee AK, Choi S, Nguyen QN, Frank SJ, Pugh T, McGuire SE, Kuban DA. Is Androgen Deprivation Therapy Necessary in Intermediate Risk Prostate Cancer Patients Treated in the Dose Escalation Era?. Int J Radiat Oncol Biol Phys 81(2):S40-S41, 2011.
- Pugh TJ, Frank SJ, Achim M, Kuban DA, Lee AK, Choi S, Nguyen Q, Hoffman K, McGuire SE, Swanson DA. Prediction of Extraprostatic Extension in Intermediate Risk Prostate Cancer: The Evolving Role of Endorectal MRI. Int J Radiat Oncol Biol Phys 81(2):S398, 2011.
- Garden AS, Morrison WH, Stugis EM, Dong L, Glisson BS, Frank SJ, Kies MS, Weber RS, Ang KK, Rosenthal DI. IMRT for Oropharyngeal Carcinoma: Patient Outcomes and Patterns of Failure. Int J Radiat Oncol Biol Phys 81(2):S15-S16, 2011.
- Frank SJ, Levy LB, van Vulpen M, Crook J, Sylvester J, Grimm P, Pugh TJ, Swanson DA. Outcomes after prostate brachytherapy are even better than predicted. Cancer. e-Pub 2011. PMID: 21751187.
- Melhus CS, Mourtada F, Mikell JK, Frank SJ, Rivard MJ. Dosimetric Influence of Brachytherapy Seed Spacers. Brachytherapy 10(1, Suppl):S94 - S95, 2011.
- Pugh TJ, Frank SJ, Kudchadker R, Swanson DA, Davis JW. Prostate MRI in Men With Intermediate-Risk Prostate Cancer: Implications for Prostate Brachytherapy Monotherapy. Brachytherapy 10(1, Suppl):S30, 2011.
- Frank SJ, Munsell MF, Pugh TJ, Kudchadker RJ, Bruno TL, Kuban DA, Lee AK, Choi S, Nguyen QN, Swanson DA. Long-Term Outcomes, Quality of Life and Patient-Reported Satisfaction Following Prostate Brachytherapy: The MD Anderson Cancer Center Experience. Brachytherapy 10(1, Suppl):S16-S17, 2011.
- Rosenthal DI, Gunn GB, Mendoza TR, Garden AS, Beadle BM, Morrison WH, Wang XS, Frank SJ, Weber RS, Ang KK, Cleeland CS. Long-term symptom burden after radiation treatment for oropharynx cancer: A comparison of 3D and IMRT techniques. J Clin Oncol 29(15S):369s, 2011.
- Gunn GB, Mendoza TR, Garden AS, Wang XS, Morrison WH, Frank SJ, Hanna EY, Lu C, Beadle BM, Ang KK,Cleeland CS, Rosenthal DI. Patient-reported fatigue in head and neck cancer survivors. J Clin Oncol 29(15S):365s, 2011.
- Papadimitrakopoulou V, Heymach J, Frank SJ, Myers J, Lin H, Tran HT, Chen C, Hirsch FR, Langmuir PB, Vasselli JR, Lippman SM, Raben D. Updated clinical and biomarker results from a Phase I study of vandetanib with radiation therapy (RT) with or without cisplatin in locally advanced head and neck squamous cell carcinoma (HNSCC). J Clin Oncol 29(15S):362s, 2011.
- Frank SJ, Johansen MJ, Martirosyan K, Gagea M, Van Pelt CS, Borne A, Carmazzi Y, Madden T. A Toxicokinetic Evaluation Of Intraprostatically Administered Cobalt Dichloride - N - Acetyl Cysteine (CoCI2-NAC) Conjugate In A Rat Model Of Systemic Exposure. Int J Radiat Oncol Biol Phys 81(2):S433 - S434, 2011.
- Gunn GB, Garcia SM, Beadle BM, Hanna EY, William WN, Garden AS, Morrison WH, Frank SJ, Ang KK, Rosenthal DI. Skin Culture and Treatment Results in Head and Neck Cancer Patients With Severe Radiation Dermatitis and Potential Suprainfection. Int J Radiat Oncol Biol Phys 78(3, Suppl):S175, 2010.
- Albert JM, Zhang M, Bruno TL, Kudchadker RJ, Swanson DA, Frank SJ. MRI-Based Treatment Planning for Prostate Brachytherapy. Int J Radiat Oncol Biol Phys 78(3, Suppl):S372-S373, 2010.
- Kuban DA, Nogueras-Gonzales GM, Hamblin L, Lee AK, Choi S, Frank SJ, Nguyen QN, Hoffman KE, McGuire SE, Munsell MF. Preliminary Report of a Randomized Dose Escalation Trial for Prostate Cancer using Hypofractionation. Int J Radiat Oncol Biol Phys 78(3, Suppl):S58-S59, 2010.
- Nguyen Q, Levy LB, Lee AK, Choi S, Frank SJ, Hoffman K, McGuire S, Kuban DA. Risk Factors Predicting Failure and Prostate Cancer Mortality in High-Risk Prostate Cancer Patients Treated with Definitive External Beam Radiation Therapy. Int J Radiat Oncol Biol Phys 78(3, Suppl):S125, 2010.
- Kim MM, Hoffman KE, Levy LB, Master P, Frank SJ, Choi S, Nguyen QN, McGuire SE, Lee AK, Kuban DA. Improvement in Prostate Cancer Outcomes Over Time: A 20-Year Analysis. Int J Radiat Oncol Biol Phys 78(3, Suppl):S191-S192, 2010.
- Morikawa LK, Kudchadker R, Kanke J, Oyervides M, Frank SJ, Lee AK, Hoffman K, Choi S, Nguyen Q, Kuban D. Endorectal Balloon in Post-Operative Radiation Therapy for Prostate Cancer. Int J Radiat Oncol Biol Phys 78(3, Suppl):S395, 2010.
- McGuire SE, Levy LB, Settle SH, Choi S, Nguyen Q, Hoffman K, Frank SJ, Lee AK, Kuban D. PSA Response to Neoadjuvant Androgen Suppression Therapy Prior to High-Dose Radiotherapy Predicts Survival in Clinically Localized High-Risk Prostate Cancer. Int J Radiat Oncol Biol Phys 78(3, Suppl):S124-S125, 2010.
- Mendoza TR, Gunn GB, Wang XS, Frank SJ, Beadle BM, Shah SH, Lu C, Hanna EY, Cleeland CS, Rosenthal DI. Impact of Symptom Burden on Survival in Patients With Head and Neck Cancer Treated With Definitive Radiation Therapy. Int J Radiat Oncol Biol Phys 78(3, Suppl):S470-S471, 2010.
- Zhang M, Munsell MF, Swanson DA, Kudchadker RJ, Albert JM, Urbauer DL, Duban DA, Bruno TL, Frank SJ. Patients Can Expect Long-Term Satisfaction After Prostate Brachytherapy. Int J Radiat Oncol Biol Phys 78(3, Suppl):S367, 2010.
- Fisher CM, Troncoso P, Swanson DA, Munsell MF, Kuban DA, Lee AK, Choi S, Nguyen QN, Frank SJ. Prostate Cancer-Specific Survival and Time to Recurrence Outcomes for Men Treated With Radical Prostatectomy, Intensity Modulated Radiation Therapy, or Brachytherapy at MD Anderson Cancer Center. Int J Radiat Oncol Biol Phys 78(3, Suppl):S147-S148, 2010.
- Frank SJ, Levy LB, van Vulpen M, Crook J, Sylvester J, Grimm P, Swanson DA. Prostate Cancer Outcomes Following Brachytherapy Are Superior To Those Predicted By the Prostogram. Int J Radiat Oncol Biol Phys 78(3, Suppl):S148, 2010.
- Choi S, Johnson JL, de Crevoisier R, Lee AK, Dong L, Frank SJ, Nguyen Q, Kuban DA. Comparison of Alignment Using Transabdominal Ultrasound Versus Computed Tomography for Prostate Cancer Patients Treated with Intensity Modulated Radiation Therapy and Androgen Deprivation Therapy. Oncology 24(4, S3):53, 2010.
- Fisher CM, Troncoso P, Kuban DA, Munsell MF, Yeh S, Lee AK, Swanson DA, Frank SJ. Do African American and White Men Have Differences in Their Rate of Pathological Upgrading? An MD Anderson Cohort Study of Radical Prostatectomy, Brachytherapy and External Beam Patients Treated From 2000-2001. Oncology 24(4, S3):50, 2010.
- Shirvani SM, Kudchadker RJ, Bruno TL, Swanson DA, Frank SJ. Letting the Catheter Out of the Bag: The Effect of Urinary Catheterization on Post-Implant Dosimetry After Prostate Brachytherapy with Palladium-103. Oncology 24(4, S3):49, 2010.
- Ludwig MS, Lev L, Frank SJ, Hoffman K, Lee AK, McGuire SE, Nguyen QN, Choi S, Woodward W, Kuban DA. Influence of Prognostic Factors on Duration of Hormone Therapy and Outcomes. Oncology 24(4, S3):46, 2010.
- Sharp HJ, Swanson DA, Zhang M, Phan J, Bruno TL, Kudchadker R, Kuban DA, Lee AK, Choi S, Nguyen Q, Frank SJ. Prostate Brachytherapy Preceded by Screening Colonoscopy Diagnoses Colorectal Cancers in Asymptomatic Patients. Oncology 24(4, S3):46, 2010.
- Frank SJ, Register S, Levy LB, Kudchadker R, Bruno TL, Swanson DA. An MRI Dose Response Analysis for Urinary Morbidity Following Prostate Brachytherapy Monotherapy in a Phase II Prospective Trial. Brachytherapy 9(2, S1):S42, 2010.
- Frank SJ. Cobalt Chloride Complex Contrast (C4) agent is safe for MRI-based Prostate Brachytherapy: A Toxicokinetic Evaluation of Intraprostatic Administration in a Rat Model. American Radium Society 92nd Annual Meeting, 2010.
- Frank SJ, Tailor R, Martirosyan K, Stafford J, Swanson D, Sing D, Choi J, Elliot A, Mourtada F, Kudchadker R, Ibbott G. C4 MRI ECAMS have no effect on I see anisotropy and are visibile after radiation exposure. Proceedings from 30th Annual Meeting of the American Brachytherapy Society 8(2), 2009.
- Whaley JT, Levy LB, Swanson DA, Kudchadker RJ, Bruno TL, Frank SJ. Sexual outcomes unaffected by penile bulb dose in prostate brachytherapy. Proceedings from 30th Annual Meeting of the American Brachytherapy Society 8(2), 2009.
- Parker PA, Latini DM, Ward JF, Pettaway C, Pisters LL, Matin S, Frank SJ, Brown V, Kuban D, Logothetis C, Kim J, Davis JW. Association between uncertainty, anxiety, and quality of life in men with prostate cancer on active surveillance. Society of Behavioral Medicine 37, 2009.
- Morikawa LK, Levy LB, Choi S, Nguyen QN, Cheung MR, Frank SJ, Lee A, Kuban DA. Relationship Between PSA Failure and Death From Prostate Cancer After Radical External Beam Radiation Therapy. Proceedings from ASTRO 2009 Annual Meeting, 2009.
- Phan J, Swanson DA, Kuban DA, Lee AK, Cheung R, Choi S, Kudchadker R, Bruno T, Levy LB, Frank SJ. Long-term rectal complications following permanent prostate brachytherapy at the University of Texas MD Anderson Cancer Center. Proceedings from the Radium Society, 2008.
- Vassiliev ON, Kudchadker RJ, Swanson DA, Kuban DA, Bruno TL, Frank SJ. Systematic Evaluation of Periurethral Stranded Seed Migration and its Dosimetric Consequences in Prostate Brachytherapy. Proceedings from ASTRO 2008, 2008.
- Frank SJ, Fisher C, Levy LB, Kudchadker R, Kuban DA, Lee AK, Cheung RM, Choi S, Bruno TL, Swanson DA. Pre-implant Urinary Symptoms Predict for Worse Urinary Outcomes. Proceedings from ASTRO 2008, 2008.
- Frank SJ, Stafford RJ, Bankson JA, Swanson DA, Kudchadker RJ, Martirosyan KS. A Novel MRI-based Approach to Prostate Brachytherapy. Proceedings from the World Congress of Brachytherapy, 2008.
- Frank SJ, Swanson DA, Kuban DA, Lee AK, Levy LB. Prostogram-predicted brachytherapy outcomes may not be universally accurate: An analysis based on the MD Anderson Cancer Center experience with I-125 brachytherapy. Proceeding from the World Congress of Brachytherapy, 2008.
- Frank SJ, Kuban DA, Lee AK, Levy LB, Kudchadker R, Bruno T, Swanson DA. Prostate Brachytherapy – The MD Anderson Cancer Center Experience. Proceedings from the American Urologic Association (AUA), 2008.
- Anderson JF, Swanson DA, Kuban DA, Lee AK, Cheung RM, Choi S, Kudchadker R, Bruno T, Levy LB, Frank SJ. Long-term urinary complications following permanent prostate brachytherapy at the University of Texas MD Anderson Cancer Center. Proceedings from the Radium Society, 2008.
- Martirosyan K, Stafford RJ, Bankson J, Frank S. Encapsulated Contrast Agent Marker (ECAM) for MRI Prostate Brachytherapy. Proceedings from The Minerals, Metals and Materials Society 2008 Annual Meeting, 2008.
- Frank SJ, Petsuksiri J, Ang KK, Morrison WH, Chao KSC, Rosenthal DI, Schwartz DL, Chronowski G, Weber RS, Garden AS. Intensity Modulated Radiation Therapy for Squamous Cell Carcinoma Metastatic to Cervical Lymph Nodes from an Unknown Primary Site; Outcomes and Patterns of Failure. Proceedings of ASTRO 49th Annual Meeting, 2007.
- Cheung R, Tucker S, de Crevoisier R, Lee A, Frank SJ, Kudchadker R, Thames , Mohan R, Kuban D. Identification of the bladder dose and volume constraints to control late urinary toxicity after external beam radiotherapy for prostate cancer. ASTRO - 48th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Philadelphia, PA, 2006.
- Frank SJ, Pisters LL, David J, Lee AK, Cheung R, Swanson D, Bassett RL, Pettaway CA, Kuban DA. Quality of Life after Monotherapy Treatment for Localized Prostate Cancer: Implant (I-125), Radical Prostatectomy, and High Dose External Beam Radiation. ASTRO - 48th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Philadelphia, PA, 2006.
- Kanke JE, Amin MA, Wong P, Ang KK, Garden AS, Morrison WH, Chao KSC, Rosenthal D, Allen P, Frank SJ. Optimizing Head and Neck Radiation Treatment Planning Using an IMRT Monoisocentric Technique with a Static Low Anterior Neck Field. ASTRO - 48th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Philadelphia, PA, 2006.
- Petsuksiri J, Frank SJ, Garden AS, Ang KK, Morrison WH, Chao KC, Rosenthal DI, Schwartz DL, Ahamad A, Esmaeli B. Radiation Therapy for Squamous Cell Carcinoma of the Eyelid. ASTRO - 48th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Philadelphia, PA, 2006.
- Frank SJ. The implementation of heterogeneity corrections for lung cancer. Texas Radiological Society (TRS) 90th Annual Scientific Meeting, The Woodlands, TX, 2003.
- Frank SJ. 45th Annual Scientific Meeting - ASTRO, Salt Lake City, UT, 2003.
- Frank SJ. Treatment planning with heterogeneity corrections for Stage I/II lung cancer. Fletcher Society Annual Scientific Meeting, Las Vegas, NV, 2002.
- Frank SJ. Heterogeneity vs. Homogeneity Corrections for Early Stage NSCLC. RSNA - Radiological Society of North America, Chicago, IL, 89th Annual Scientific Meeting, 2002.
- Frank SJ. Definitive treatment of vaginal cancer with radiation therapy: The MD Anderson Cancer Center (MDACC) Experience. 1970-2000, 2000.
Book Chapters
- Phan Jack, Frank SJ, Brown Paul D. Clinical Applications of Radiotherapy for Skull Base Tumors. In: Comprehensive Management of Skull Base Tumors. Second. Thieme Medical Publishers, Inc: New York, NY, 164-190, 2021.
- Phan Jack, Frank SJ, Brown Paul D. Radiotherapy for Skull Base Tumors: Principles and Techniques. In: Comprehensive Management of Skull Base Tumors. Second. Thieme Medical Publishers, Inc: New York, NY, 141-163, 2021.
- Frank SJ, Garden AS, Ang K. Principals and Techniques of Radiotherapy and Chemotherapy for Nasal Cavity and Paranasal Sinus Tumors. In: Tumors of Nose, Sinus and Nasopharynx. Thieme, Stuttgart: Germany, 2015.
- Frank SJ, Gunn GB. Radiotherapy- The “Particle-rs” of energy, dose and delivery method. In: Otolaryngologic Clinics of North America: Oral Cavity and Oropharyngeal Cancer. Elsevier: Philadelphia, PA, 2013.
- Frank SJ, Ahamad A, Ang KK. Cancer of the Nasal Cavity and Paranasal Sinuses. In: Clinical Radiation Oncology, 761-777, 2012.
- Frank SJ, Selek U. Proton Beam Radiation Therapy for Head and Neck Malignancies. In: Curr Oncol Rep. 3, 202-7, 2010.
Books (edited and written)
- Frank SJ, Xiaorong Ronald Zhu. Proton Therapy (Indications, Technique and Outcomes). Elsevier: Philadelphia, PA, 2020.
Grant & Contract Support
Title: | A Novel Nanoparticle Approach to MRI Prostate Brachytherapy |
Funding Source: | Prostate Cancer Foundation |
Role: | Principal Investigator |
Title: | An MRI-based approach to prostate brachytherapy |
Funding Source: | MDACC (TRC) |
Role: | Principal Investigator |
Title: | Seeds and Markers for MRI-based Treatment |
Funding Source: | Texas Ignition Fund |
Role: | Principal Investigator |
Title: | Radiological Physics Center |
Funding Source: | NIH/NCI |
Role: | Co-Principal Investigator |
Title: | Fabrication and validation of implantable MRI markers for prostate cancer treatment |
Funding Source: | NIH/NCI |
Role: | Co-Principal Investigator |
Title: | An in vivo plastic scintillation detector for ultrasound-guided seed implantation during low dose-rate prostate brachytherapy |
Funding Source: | Odyssey Program |
Role: | Collaborator |
Title: | Institutional Start-up Funds |
Funding Source: | UT MD Anderson Cancer Center |
Role: | Principal Investigator |
Title: | MRI-LINAC Project |
Funding Source: | ELEKTA |
Role: | Co-Principal Investigator |
Title: | Magnetic Resonance Imaging Biomarkers of Radiotherapy-Associated Organ at Risk Injury for Patients enrolled on a Randomized Trial of Photon/Proton Radiotherapy for Oropharyngeal Cancer |
Funding Source: | Center for Radiation Oncology Research |
Role: | Co-Investigator |
Title: | Optimization of MR workflow sequences for image-registration, bulk density assignment, target delineation, and dose calculation for head and neck |
Funding Source: | ELEKTA |
Role: | Co-Principal Investigator |
Title: | Optimizing Proton Therapy - Project 2: Improving the Therapeutic Ratio of Proton Radiation Therapy in Challenging Clinical Sites |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Phase II/III Randomized Trial of Intensity-Modulated Proton Beam Therapy (IMPT) versus Intensity-Modulated Photon Therapy (IMRT) for the Treatment of Oropharyngeal Cancer of the Head and Neck (2012-0825) |
Funding Source: | HI-CRSP |
Role: | Principal Investigator |
Title: | A framework for the analysis of multiparametric MRI data in a 300 patient prostate cancer image-guided clinical trial and the application for the disease control with tumor response assessment |
Funding Source: | The Center for Radiation Oncology Research, MDACC |
Role: | Co-Principal Investigator |
Title: | Improving the clinical effectiveness and understanding of the biophysical basis - Core A: Administrative |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Improving the clinical effectiveness and understanding of the biophysical basis - Project 1: Randomized Clinical Trials to Exploit the Physical and Biophysical Properties of Protons including Reduction in Dose Bath with Protons |
Funding Source: | NIH/NCI |
Role: | Protocol Chair |
Title: | Improving the clinical effectiveness and understanding of the biophysical basis - Project 2: Exploratory Clinical Trials to Exploit the Physical and Biophysical Properties of Protons including Reduction in Dose Bath with Protons |
Funding Source: | NIH/NCI |
Role: | Project Leader |
Title: | Prexasertib (CHK1/2 inhibitor) targeting DNA damage to improve treatment gain from protons/X-ray radiotherapy |
Funding Source: | Eli Lilly |
Role: | Principal Investigator |
Title: | Multi-modality MRI/CT Markers for Improved Assessment of Prostate Cancer Treatment with Brachytherapy |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |
Title: | Lingual Strength & Dysphagia after Oropharynx Cancer: Proton vs. Photon Radiation |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | PBT vs. Photon Study for Certain Breast Cancers |
Funding Source: | PCORI |
Role: | Co-Investigator |
Title: | MR-guided radiation therapy using positive contrast multi-imaging modality intra-prostatic fiducial markers for external beam radiotherapy in localized prostate cancer |
Funding Source: | NIH/NCI |
Role: | Co-Principal Investigator |
Title: | Phase II/III Randomized Trial of Intensity-Modulated Proton Beam Therapy (IMPT) versus Intensity-Modulated Photon Therapy (IMRT) for the Treatment of Oropharyngeal Cancer of Head and Neck Cancer, 2012-0825 |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |
Title: | Understanding Biological and Physical Factors Affecting Response to Proton Therapy to Improve its Clinical Effectiveness |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Collaborator |
Title: | Effects of HPV status and fraction numbers on the relative biological effectiveness of proton beam therapy in head and neck cancer models |
Funding Source: | The University of Texas MD Anderson Cancer Center Institutional Research Grant Program |
Role: | Principal Investigator |
Title: | Assessing and Understanding the Impact of Physical and Biological Factors on - Project 1: Randomized Clinical Trials to Exploit the Physical and Biophysical Properties of Protons including Reduction in Dose Bath with Protons |
Funding Source: | NIH/NCI |
Role: | Investigator |
Title: | Improving the Clinical Effectiveness and Understanding of the Biophysical Basis - Core A: Administrative Core |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Assessing and Understanding the Impact of Physical and Biological Factors on - Core A: Administrative |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Phase II/III Randomized Trial of Intensity-Modulated Proton Beam Therapy (IMPT) versus Intensity-Modulated Photon Therapy (IMRT) for the treatment of Oropharyngeal Cancer of the Head and Neck |
Funding Source: | Hitachi |
Role: | Principal Investigator |
Title: | Improving the Clinical Effectiveness and Understanding of the Biophysical Basis - Project 2: Exploratory Phase I/II Clinical Studies to Improve the Therapeutic Ratio of Proton Radiation Therapy |
Funding Source: | NIH/NCI |
Role: | Project Leader |
Title: | Improving the Clinical Effectiveness and Understanding of the Biophysical Basis - Project 1: Assessment of Effectiveness of IMPT vs. IMRT through Phase II Randomized Clinical Trials |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | MR-guided radiation therapy using positive contrast multi-imaging modality intra-prostatic fiducial markers for external beam radiotherapy in localized prostate cancer |
Funding Source: | NIH/NCI |
Role: | Co-Principal Investigator |
Title: | Molecular characterization of proton versus photon radiation for personalized head and neck cancer therapy |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Principal Investigator |
Title: | The effect of HPV, radiation fractions and proton beam linear energy transfer on protons relative biological effectiveness in head and neck cancers |
Funding Source: | UT MD Anderson Radiation Oncology Division |
Role: | Principal Investigator |
Title: | Exploiting the molecular characteristics with protons to improve treatment benefits |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |
Title: | Proteomic elucidated molecular changes of adenoid cystic carcinoma to proton or photon to improve treatment benefits |
Funding Source: | Emerson Collective Cancer Research Fund and MD Anderson |
Role: | Principal Investigator |
Title: | Proteomic elucidated molecular changes of adenoid cystic carcinoma to proton or photon to improve treatment benefits |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |
Title: | Exploring the effect of proton versus photon radiation on human immune cells |
Funding Source: | UT MD Anderson Radiation Oncology Division |
Role: | Principal Investigator |
Title: | Exploring the effect of proton versus photon radiation on human immune cells |
Funding Source: | UT MD Anderson Stiefel |
Role: | Principal Investigator |
Title: | Proteomics elucidated molecular mechanisms of adenoid cystic carcinoma response to radiation and enhancing tumor response by precision radiation with targeted therapy |
Funding Source: | UT MD Anderson and Baylor College of Medicine Head and Neck SPORE |
Role: | Principal Investigator |
Title: | Exploring the effect of proton versus photon radiation on the human immune system |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |
Title: | Development of magnetic resonance T1, T2 and computed tomography positive contrast multi-imaging modality fiducial markers for image-guided brachytherapy |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Principal Investigator |
Title: | Exploring the effect of proton versus photon radiation on the human immune system |
Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
Role: | Principal Investigator |
Title: | Customizing precision radiation modalities via identifying personalized relative biological effectiveness |
Funding Source: | NIH/NCI |
Role: | Principal Investigator |
Title: | Investigating patient, tumor and treatment factors underlying sensitivity of cancers and normal tissues to proton vs. photon radiation |
Funding Source: | NIH/NCI |
Role: | Core Leader |
Title: | Development of novel positive contrast MRI markers and MRI sequences for precision MRI-Assisted Radio Surgery (MARS) for prostate cancer |
Funding Source: | MD Anderson - CCSG Radiation Oncology and Cancer Imaging Program |
Role: | Co-Principal Investigator |
Title: | Rusalatide Acetate (TP508) Mitigation of Genotoxic Radiation Damage in Human Lens Epithelial Cells |
Funding Source: | Affirmed Pharma, Inc - R41EY033583 |
Role: | Principal Investigator |
Title: | ATLAS: Adverse Events Study in Proton Therapy Using Dose Linear Energy Transfer Volume Histogram and Seed Spot Analysis |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Targeting replication stress and homologous recombination repair mechanisms in HPV-positive and negative head and neck cancer |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Title: | Biological, Imaging, and Dosimetric Markers of Enhanced Tumor Control and Preserved Normal Organ Functions after proton or X-Ray Radiation for Head and Neck Cancer |
Funding Source: | NIH |
Role: | Principal Investigator |
Title: | OPC Survivor: Optimizing OroPharyngeal Cancer Survivorship |
Funding Source: | NIH/NCI |
Role: | Project Principal Investigator |
Title: | Establishing the Value of Proton Therapy for Head and Neck Cancer: Assessing Cost-Effectiveness and Financial Toxicity of Therapy |
Funding Source: | National Association of Proton Therapy (NAPT) |
Role: | PD/PI |
Title: | Investigating the Effect of FLASH-Radiotherapy on Tumor and Normal Tissue |
Funding Source: | NIH/NCI |
Role: | PD/PI |
Title: | Extend Healthy Life in Space by Characterizing Radiation Induced Pro-Inflammatory Response and Enhancing Wound Repair and Recovery with Radiation Mitigating Thrombin Peptide |
Funding Source: | NASA and Baylor College of Medicine Translational Research Institute for Space Health |
Role: | PI Mentor |
Title: | Moore Foundation Inventor Fellows |
Funding Source: | Gordon and Betty Moore Foundation |
Role: | Co-Investigator |
Title: | Rusalatide Acetate (TP508) Delivery and Radio-Mitigation Effect in a Murine Model of Radiation-Induced Keratopathy |
Funding Source: | NIH/NEI |
Role: | Co-Principal Investigator |
Title: | FLASH Proton Spatial Fractionated Radiotherapy on Prostate Cancer |
Funding Source: | ROSI-MDA |
Role: | Principal Investigator |
Title: | Combining DNA damage repair-targeted therapy with proton, carbon ion, or photon radiotherapy to improve outcomes in prostate cancer and head and neck cancer |
Funding Source: | Sister Institution Network Fund Scientific Review Committee |
Role: | Principal Investigator-MDACC |
Title: | Preclinical in vivo study of the biological effects of active magnetic fields on radiation response of human solid tumors and normal tissues |
Funding Source: | ELEKTA |
Role: | Principal Investigator |
Title: | Preclinical in vitro study of the biological effects of active magnetic fields on radiation response of human solid tumor cells |
Funding Source: | ELEKTA |
Role: | Principal Investigator |
Title: | Quantitative Imaging Analysis Core |
Funding Source: | The University of Texas MD Anderson Cancer Center |
Role: | Co-Principal Investigator |
Title: | RSNA Resident Research Grant |
Funding Source: | Radiological Society of North America (RSNA) |
Role: | PI Mentor |
Title: | Online Adaptive Proton Therapy |
Funding Source: | NIH/Mayo Clinic RO1 |
Role: | Co-Investigator |
Title: | FLASH Mini-Proton Beam Spatially Fractionated Radiotherapy in Prostate Cancer |
Funding Source: | NCI/National Cancer Institute R21 |
Role: | Principal Investigator |
Title: | Dose Linear-Energy-Transfer Volume Histogram and Dosimetric Seed Spot Analysis in Spot Scanning Proton Therapy |
Funding Source: | NIH/NCI |
Role: | Co-Investigator |
Patient Reviews
CV information above last modified September 10, 2024