Steven H. Lin, M.D., Ph.D.
Department of Thoracic Radiation Oncology, Division of Radiation Oncology
About Dr. Steven H. Lin
Present Title & Affiliation
Primary Appointment
Professor, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Associate Professor, Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Professor, Department of Thoracic Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Research Interests
Dr. Lin's laboratory has several lines of research. The first is to identify novel agents to combine with radiation to enhance treatment effects through the application of high throughput screening methods. Second, Dr. Lin is interested in identifying novel gene targets that could enhance the systemic immune response in combination with radiation therapy. Third, he is seeking ways through imaging or blood based markers to assess response to treatment for lung and esophageal cancer patients.
Clinical Interests
Dr. Lin's clinical interests lie in improving the clinical outcomes of lung and esophageal cancer patients receiving radiation therapy. He has a special interest in the application of advanced radiation technologies such as Intensity Modulated Radiation Therapy (IMRT) and proton beam therapy as a way to minimize toxicity and improve clinical outcomes for esophageal cancer patients. Dr. Lin also has interest in using various imaging and blood based biomarkers to predict response to treatment
Education & Training
Degree-Granting Education
| 2004 | The University of California Irvine Medical Center, Irvine, California, US, Medicine, Neuropharmacology, MD, PhD |
| 2002 | The University of California Irvine Medical Center, Irvine, California, US, Pharmacology, PhD |
| 1995 | The University of California, Riverside, California, US, Biochemistry, MS |
| 1994 | BS, Riverside, California, US, Biology, The University of California |
| 1992 | California Polytechnic University, Pomona, California, US, Architecture (transferred) |
Postgraduate Training
| 2005-2009 | Clinical Residency, Radiation Oncology, The John Hopkins Hospital, Baltimore, Maryland |
| 2004-2005 | Clinical Internship, Internal Medicine, Loma Linda University Medical Center, Loma Linda, California |
| 2001-2002 | Post-Ph.D, Neuropharmacology, Neogene Technologies, Irvine, California |
Licenses & Certifications
| 2023 | Georgia Composite Medical Board |
| 2023 | Oklahoma State Board of Medical Licensure |
| 2023 | Arizona Board of Medical Examiners |
| 2023 | Alabama Board of Medical Examiners |
| 2023 | Louisiana State Board of Medical Examiners |
| 2021 | Florida Board of Medicine |
| 2010 | American Board of Radiology |
| 2009 | Texas Medical Board |
| 2006 | Medical Board of California |
| 2006 | General Medical License |
| 2001 | Tennessee Board of Medical Examiners |
Experience & Service
Faculty Academic Appointments
Associate Professor, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2021
Assistant Professor, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2009 - 2015
Administrative Appointments/Responsibilities
Director of Research, Department of Thoracic Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2023 - Present
Extramural Institutional Committee Activities
Committee Member, CRAC/ReCINT Committee, The University of Texas MD Anderson Cancer Center, 2016 - Present
Vice Chair, Institutional Review Board 5, The University of Texas MD Anderson Cancer Center, 2015 - Present
Vice Chair, Institutional Research Grant Committee-Basic Study Section Committee, The University of Texas MD Anderson Cancer Center, 2015 - 2016
Committee Member and Grants Reviewer, Institutional Research Grant Committee-Basic Study Section Committee, The University of Texas MD Anderson Cancer Center, 2013 - 2015
Associate Member, Institutional Review Board 5, The University of Texas MD Anderson Cancer Center, 2011 - 2015
Editorial Activities
Associate Editor, Precision Cancer Medicine; Chinese Clinical Oncology, 2020 - Present
Associate Editor, Journal of the Immunotherapy of Cancer, 2018 - Present
Associate Editor, Frontiers in Oncology; Frontiers Media, 2018 - Present
Associate Editor, Public Library of Science One, 2018 - Present
Honors & Awards
| 2025 - Present | Fellow of American Society of Radiation Oncology |
| 2019 | Steven Leibel Memorial Award, ASTRO/ABR Foundation |
| 2012 - 2014 | Comparative Effectiveness Research on Cancer in Texas Fellow, CERCIT |
| 2010 - 2013 | ASTRO Junior Faculty Fellow, American Society for Radiation Oncology (ASTRO) |
| 2008 - 2009 | RSNA Research Resident Grant |
| 2008 | ABS/Nucletron HDR Brachytherapy Fellowship |
| 2004 | Alpha Omega Alpha, University of California, Irvine School of Medicine |
| 2001 | Henry Wood Elliott Award in Pharmacology |
| 1998 | American Heart Association Medical Student Fellowship |
| 1997 | UC Regents Research Fellowship |
| 1996 - 1997 | Dean's Award, University of California, Irvine School of Medicine |
| 1996 | Donald E. Pinder, M.D. Memorial Award |
| 1996 | Dr. Grace Bell Award |
| 1995 - 2004 | Medical Scientist Training Program Fellowship and Stipend |
| 1994 | Phi Beta Kappa, University of California |
| 1994 | Summa Cum Laude, University of California |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2024. Circulating Polyploid Giant Cells in Lung Cancer Prognosis and Clinical Outcome. Invited. Houston, Texas, US.
- 2018. The Significance of Radiation-Induced Lymphopenia and the Potential for Mitigation by Proton Therapy in Esophageal Cancer. Invited. MD Anderson-Stanford Conference on Advanced Techniques and Technologies for Radiation Oncology. Houston, Texas, US.
- 2018. Particle Therapy. Invited. Radiation Oncology Research Retreat. Houston, Texas, US.
National Presentations
- 2024. Translating Research into Practice: Designing Clinical Trials Based on Solid Preclinical Data. Invited. Washington DC, US.
- 2024. Chemotherapy-Free Radioimmunotherapy in Locally Advanced NSCLC. Invited. Kona, Hawaii, US.
- 2024. Challenge for Accrual to Proton Trials: Provider Barriers: Patient Selection and Enrollment Equipose. Invited. Orlando, Florida, US.
- 2023. Immunotherapy in Unresectable Stage III NSCLC. 2023 Multidisciplinary Thoracic Cancers Symposium. New Orleans, Louisiana, US.
- 2023. Immunotherapy in the Setting of SBRT. Invited. 2023 IASLC Targeted Therapy Lung Cancer Meeting. Santa Monica, California, US.
- 2023. Understanding Radiation Induced Lymphopenia for Mitigation Strategies to Enhance Cancer Outcomes. Visiting. Durham, North Carolina, US.
- 2023. Radiotherapy Options in Oligometastatic Disease. Invited. San Diego, California, US.
- 2023. Evidence for the Benefit of Protons: Trial Design and Patient Selection. Invited. Philadelphia, Pennsylvania, US.
- 2022. Understanding the Differential Effects of Proton Therapy on Radiation Induced Immunosuppression. Proton Therapy Cooperative Group. Miami, Florida, US.
- 2022. Clinical Trial Landscape in Localized Esophageal Cancer. Global Collaborative Oncology Group (GCOG) Annual Meeting. Houston, Texas, US.
- 2022. Proton Therapy for Esophageal and Gastroesophageal Cancers. International Gastric Cancer Congress. Houston, Texas, US.
- 2021. Proton Therapy for Gastroesophageal Cancer. ASTRO Educational Session # 4947. Virtual.
- 2021. Sequential Monitoring of PD-L1 on Circulating Tumor Stromal Cells Predicts Survival Outcomes for Unresectable Stage 3 NSCLC Treated with Immunotherapies After Definitive Chemoradiation. ASTRO Scientific Session: Oral Presentation. Virtual.
- 2021. Proton Therapy for Esophageal Cancer. PTCOG-NA. Virtual.
- 2021. The Role of Proton Therapy in the Treatment of Oesophageal Cancer. ESTRO. Virtual.
- 2020. The Role of Radiotherapy in the Era of Immunotherapy, Practical Applications of New Agents in Oncology Conference. San Antonio, Texas, US.
- 2018. Proton Therapy for Esophageal Cancer. The National Proton Conference. Scottsdale, Arizona, US.
- 2018. Chemoradiation plus Trametinib in Locally Advanced NSCLC, 18th Annual Targeted Therapies in Lung Cancer Meeting. Santa Monica, California, US.
- 2018. Phase III Randomized Trial of Proton Beam Therapy versus Intensity Modulated Photon Radiotherapy (IMRT) for the treatment of Esophageal Cancer. Phoenix, Arizona, US.
- 2018. Phase I Trial of Accelerated or Conventionally Fractionated Radiotherapy Combined with ImmunotHerapy in PD-L1 high Locally Advanced Non-Small Cell Lung Cancer (NSCLC) (ARCHON-1). Phoenix, Azirona, US.
- 2017. The Role of Molecular/Functional Imaging for Radiotherapy in Esophageal Cancer. Chicago, Illinois, US.
- 2017. Phase I Trial of Accelerated or Conventionally Fractionated Radiotherapy Combined with ImmunotHerapy in PD-L1 high Locally Advanced Non-Small Cell Lung Cancer (NSCLC) (ARCHON-1). Phoenix, Arizona, US.
- 2017. Phase III Randomized Trial of Proton Beam Therapy versus Intensity Modulated Photon Radiotherapy (IMRT) for the treatment of Esophageal Cancer. Phoenix, Azirona, US.
- 2016. Imaging Surrogate Markers in Esophageal Cancer. Chicago, Illinois, US.
- 2016. Optimizing preclinical and clinical investigations of radiation-drug combinations. American Society for Radiation Oncology. Boston, Massachusetts, US.
- 2016. Enhancing the Value of Proton Therapy: Challenges and Opportunities to Improve Cancer Therapy. Boston, Massachusetts, US.
- 2014. Proton Therapy Trial Status for Esophageal Cancer. PTCOG-NA. Houston, Texas, US.
- 2013. Radiotherapy Management of Thoracic Malignancies at MD Anderson Cancer Center. Orlando, Florida, US.
- 2012. Accelerating Progress of Biomarker-Directed, Molecularly-Targeted Radiation Therapy. Bethesda, Maryland, US.
International Presentations
- 2026. Single Cell TRANSCRIPTOMIC and T-Cell Receptor Diversity Analysis of PERIPHERAL Blood Lymphocytes Comparing Proton Versus Photon-Based Chemoradiation In Esophageal Cancer. Invited. 64th Annual Conference of the Particle Therapy Cooperative Group (PTCOG) Conference. Deauville, FR.
- 2024. Optimizing Chemoradiation in Oesophageal Adenocarcinomas: Understanding Mechanism of CRT Resistance to Develop Mitigating Strategies. Invited. Cambridge, GB.
- 2024. Understanding Radiation Resistance in Esophageal Adenocarcinoma to Identify Mitigating Strategies. Invited. Montreal, CA.
- 2024. Palliative Radiotherapy for Stage IV Esophageal Cancer. Invited. The International Society of Diseases of the Esophagus. Edinburgh, GB.
- 2024. Organ Preservation Strategy Using Chemoradiation by Treatment Response Biomarkers in Esophageal Adenocarcinoma. Visiting. Taipei, TW.
- 2024. Translational Research and Future Directors in Charged Particle Radiobiology. Invited. Singapore, SG.
- 2024. Management of Unresectable Locally Advanced NSCLC in the Era of Immunotherapy. Invited. Istanbul, TR.
- 2023. PD-L1 on Circulating Stromal Cells Predicts 3 year Survival in Unresectable Stage 3 NSCLC Treated with Immunotherapy Post Definitive Chemoradiation. World Conference on Lung Cancer 2023, SG.
- 2023. Harnessing the immunologic impact of particle therapy to optimize cancer therapy. 17th International Congress for Radiation Research. Montreal, CA.
- 2022. Understanding Radiation Induced Immunosuppression for Potential Mitigation Strategies. TASTRO. Taipei, TW.
- 2022. Developing Drug-Combination Therapies with Radiation Therapy: Challenges and Opportunities. Global Cancer Consortium Mini-Symposium. Virtual.
- 2021. Predictive Biomarkers for the Management of Unresectable Locally Advanced Non-Small Cell Lung Cancer. 34th Annual Meeting of the Japanese Society of Radiation Oncology. Virtual, US.
- 2021. Individualized Decision Making Based on Chemoradiation Treatment Response in Esophageal Cancer. 17th ISDE World Congress for Esophageal Diseases. Virtual.
- 2018. SABR for early stage NSCLC: Can we do better?. 2018 World Lung Conference. Toronto, CA.
- 2018. The Promise of Combining Immunotherapies with Radiotherapy to Improve Cures in Locally Advanced NSCLC. Tianjin Oncology Forum. Tianjin, CN.
- 2018. Lymphocyte Sparing Effects of Proton Therapy in Esophageal Cancer. Conference on Clinical and Experimental Research in Radiation Oncology (C.E.R.R.O). Les Menuires, US.
- 2016. Advances in Radiotherapy for Esophageal Cancer. Chinese Society for Therapeutic Radiology and Oncology. Chengdu, CN.
- 2014. . Circulating Tumor Cells with Markers of Epithelial-Mesenchymal Transition are associated with Distant Metastatic Failures in Lung Cancer Patients treated with Definitive Chemoradiation. 29th Working Party on Clinical and Experimental Research in Radiation Oncology (C.E.R.R.O.). Les Menuires, FR.
- 2013. Challenges and Opportunities in Molecular Targeted Radiation Therapy in Non-Small Cell Lung Cancer. International Symposium on Respiratory Diseases. Shanghai, CN.
- 2012. Advances in Radiation Technologies to Improve Treatment outcomes in Esophageal Cancer. 27th Working Party on Clinical and Experimental Research in Radiation Oncology (C.E.R.R.O.). Les Menuires, FR.
- 2011. The potential Utility of Epithelial-Mesenchymal Biomarkers in Lung Cancer. 26th Working Party on Clinical and Experimental Research in Radiation Oncology (C.E.R.R.O.). Les Menuires, FR.
Formal Peers
- 2022. Diagnostic and Prognostic Value of Circulating Tumor Associated Multinucleated Stromal Cells in Epithelial Cancers. Invited. New York, NY, US.
- 2021. Radiation Induced Heart Disease: Mechanism and Prevention. Invited. Houston, TX, US.
- 2021. Proton Therapy for Esophageal Cancer. Invited. Houston, TX, US.
- 2021. Mitigating Radiation Induced Lymphopenia to Enhance Cancer Therapy. Invited. Chennai, IN.
- 2021. Biomarker Guided Management of Unresectable Locally Advanced Non-Small Cell Lung Cancer. Invited. Philadelphia, PA, US.
- 2021. Biomarker Guided Management of Unresectable Locally Advanced Non-Small Cell Lung Cancer. Invited. Philadelphia, PA, US.
- 2021. Understanding Radiation Induced Immunosuppression for Mitigation Strategies. Invited. Paris, FR.
- 2020. Treatment of Esophageal Cancer – The Way Forward. Invited. Chennai, IN.
- 2020. Yin and Yang of Radiation Therapy on Cardiac Health and Disease. Invited. Houston, TX, US.
- 2019. Enhancing Immunotherapy-Radiotherapy Efficacy by Mitigating Radiation-Induced Lymphopenia. Invited. Coimbra, PT.
- 2019. Enhancing Immunotherapy-Radiotherapy Efficacy by Mitigating Radiation-Induced Lymphopenia. Invited. San Diego, CA, US.
- 2019. Enhancing Cancer Outcomes in Esophageal Cancer through Advanced Radiation Approaches. Invited. Taipei, TW.
- 2019. Mitigating Risk of Radiation-Induced Lymphopenia to Enhance Cancer Therapy. Invited. Manchester, GB.
- 2019. Tailoring therapy based on risk assessment for patients with esophageal cancer. Invited. New Dehli, IN.
- 2019. Innovative Approaches in the Management of Locally Advanced NSCLC. Invited. Shijiazhuang, CN.
- 2019. NRG Phase I Radiation Drug Development Efforts - Why Pharma should come to our door. Invited. Bethesda, MD, US.
- 2019. Proton Therapy versus Photon Therapy for Esophageal Cancer. Invited. Coral Gables, FL, US.
- 2019. Individualized Decision Making Through Treatment Response Assessment in Esophageal Cancer. Invited. Portland, OR, US.
- 2019. Thoracic Cancers Educational Section. Invited. Long Beach, CA, US.
- 2018. Individualized Decision Making Through Treatment Response in Esophageal Cancer. Invited. Quebec, CA.
- 2018. Harnessing the systemic effects of radiation therapy in the era of immunotherapy in NSCLC. Invited. Basel, CH.
- 2018. Proton Therapy for Esophageal Cancer. Invited. Miami, FL, US.
- 2018. Enhancing Cures in Lung Cancer through Immunotherapy and Radiotherapy Approaches. Invited. Jinan, CN.
- 2018. Improving Access through Education, Awareness and Outcomes. Invited. Scottdale, AZ, US.
- 2018. Individualized Decision Making Through Treatment Response in Esophageal Cancer. Invited. Philadelphia, PA, US.
- 2018. The mechanism of the anti-chemotherapy induced neutropenia (anti-CIN) and anti-cancer actions of plinabulin. Invited. La Jolla, CA, US.
- 2018. Lymphocyte Sparing Effects of Proton Therapy in Esophageal Cancer. Invited. Baltimore, MD, US.
- 2018. Advances in Radiotherapy for Upper GI Malignancies. Invited. Los Angeles, CA, US.
- 2016. Individualized Decision Making Through Treatment Response in Esophageal Cancer. Invited. Utrecht, NL.
- 2016. Proton Therapy for Esophageal Cancer. Invited. Utrecht, NL.
- 2016. Multidisciplinary Management of Esophageal Cancer. Invited. Xi'an, Shaanxi, CN.
- 2016. Enhancing the Therapeutic Ratio in the Management of Gastroesophageal Cancers. Invited. Hiroshima, JP.
- 2016. Cancer Immunology and Immunotherapy: Recent Progress and Future Perspectives. Invited. Tokyo, JP.
- 2016. IO/RT in Lung Cancers – What is the Scientific Landscape. Invited. Phoenix, AZ, US.
- 2016. Improving the Standard of Care for Stage III NSCLC Combining Immunotherapy with Chemoradiotherapy. Invited. Houston, TX, US.
- 2014. Proton Beam Therapy for Esophageal Cancer: An Update on Progress. Invited. Rochester, MN, US.
- 2014. Improving the Therapeutic Index in the Management of Esophageal Cancer. Invited. Orange, CA, US.
- 2014. Improving the Therapeutic Index in the Management of Esophageal Cancer. Invited. Irvine, CA, US.
- 2014. Treatment Technology Utilization Workshop: Practical Application of Thoracic IMRT--Making the Transition for Lung and Esopahgeal Cancers. Invited. Dallas-Fort Worth, TX, US.
- 2014. Screening Drugs as Radiation Sensitizers for Clinical Translation. Invited. Houston, TX, US.
- 2013. Proton Therapy for Esophageal Cancer: The MD Anderson Experience. Invited. Denver, CO, US.
- 2013. Proton Therapy for Esophageal Cancer: Technique and Challenges. Invited. Baltimore, MD, US.
- 2013. Accelerating Progress of Molecularly-Targeted Radiation Therapy in Locally Advanced Non-Small Cell Lung Cancer. Invited. Guangzhou, CN.
- 2013. Enhancing the Therapeutic Ratio in the Treatment of Carcinoma of the Esophagus. Invited. Guangzhou, CN.
- 2012. Enhancing the Therapeutic Ratio in the Radiotherapeutic Management of Esophageal Cancer. Invited. Los Angeles, CA, US.
Grant & Contract Support
| Date: | 2025 - 2027 |
| Title: | Immune Modulating Effects of COVID-mRNA in Patients with Esophageal Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | FP00023139 |
| Date: | 2025 - 2028 |
| Title: | Targeting glutamine metabolism with glutaminase 1 inhibition to radiosensitize lung cancer |
| Funding Source: | CPRIT |
| Role: | Co-I |
| ID: | RP250168 |
| Date: | 2023 - 2028 |
| Title: | Combining Effective Radiotherapeutic-strategies to enhance Vaccinations against Cervical cancer (CERVICAL) ROBIN Project 2: Molecular and immune drivers of HPV-specific responses following radiotherapy for cervical cancer |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | U54CA281787 |
| Date: | 2022 - 2027 |
| Title: | Acquired Resistance to Therapy and Iron (ARTI) Center – Project 3 |
| Funding Source: | NIH/NCI |
| Role: | Project Leader |
| ID: | FP0015284 |
| Date: | 2022 - 2023 |
| Title: | Pilot Study for Detecting Non-Alcoholic Steatohepatitis associated Hepatocellular Carcinoma using Integrated Biochip Imaging of Tumor Exosomes (iCITE) |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2021 - 2026 |
| Title: | Integrating patient-specific clinical and biological factors towards individualizing utilization of proton and photon radiation therapy |
| Funding Source: | NIH/NCI |
| Role: | Project Leader |
| ID: | 1P01CA261669-01 |
| Date: | 2021 - 2022 |
| Title: | Delineate the Single-cell Level Functional Heterogeneity of Tumor Microenvironment and Its Association with Chemoradiation Responses in Esophageal Adenocarcinoma |
| Funding Source: | MDACC ROSI |
| Role: | PI |
| Date: | 2021 - 2022 |
| Title: | Delineating Single-cell Level Intra-tumoral Heterogeneity and Its Association with Chemoradiation Responses in Esophageal Adenocarcinoma |
| Funding Source: | MDACC IRG |
| Role: | PI |
| Date: | 2021 - 2026 |
| Title: | Streamlined and comprehensive circulating tumor exosome profiling by microfluidic arrayed nanoplasmonic sensors and actuators |
| Funding Source: | NIH/NIBIB |
| Role: | Co-PI |
| ID: | 1R01EB030623-01 |
| Date: | 2020 - 2025 |
| Title: | Targeting ferroptosis in radioresistance in lung cancer: mechanism and preclinical translation |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | 1R01CA247992-01A1 |
| Date: | 2020 - 2025 |
| Title: | Molecularly-based outcome and toxicity prediction after radiotherapy for lung cancer |
| Funding Source: | Stanford University |
| Role: | Co-PI |
| ID: | 1R01CA254179-01 |
| Date: | 2019 - 2022 |
| Title: | Mitigating High Grade Radiation-induced Lymphopenia Through Pretreatment Autologous Lymphocyte Infusion |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1-R21-CA240881 |
| Date: | 2019 - 2024 |
| Title: | Cancer Center Support Grant: Lung Cancer |
| Funding Source: | Cancer Center Support Grant: Lung Cancer |
| Role: | Co-PI |
| ID: | P30CA016672 |
| Date: | 2019 - 2021 |
| Title: | Targeting Tankyrases to modulate the LkB1/AMPK pathway to block tumorigenesis and mitigate therapy resistance |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1-R21-CA24001 |
| Date: | 2018 - 2019 |
| Title: | Southwest Early Clinical Trials Consortium |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| Date: | 2017 - 2022 |
| Title: | Enhancing Chemoradiation Efficacy through Unbiased Drug Discovery Approaches |
| Funding Source: | NIH/NCI |
| Role: | PI |
| ID: | 1-U01-CA216468-01 |
| Date: | 2017 - 2018 |
| Title: | Giant Macrophage-Like Cells as Blood-Based Biomarker for Lung Cancer Recurrence |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | 1R43CA206840 |
| Date: | 2016 - 2021 |
| Title: | Strategic Alliance_Lung-NSCLC Stage III-IV Therapy Response Assessment |
| Funding Source: | Hitachi |
| Role: | PI |
| Date: | 2016 - 2018 |
| Title: | Combining Chemoradiation with Anti-Phosphotidylserine Blockade Promotes Immunogenic Phagocytosis and Generates Long-Lasting Anti-Tumor Immunity |
| Funding Source: | Peregrine Pharmaceuticals, Inc |
| Role: | PI |
| Date: | 2016 - 2018 |
| Title: | Development of a Multiparametric Predictor for Radiation-Induced Lung Damage after Lung Cancer Therapy |
| Funding Source: | MDACC-SINF |
| Role: | PI |
| Date: | 2015 - 2020 |
| Title: | Noninvasive Monitoring of Lung Cancer Patients Treated with Radiotherapy |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | 1R01CA188298-01A1 |
| Date: | 2015 - 2016 |
| Title: | GUARDIAN-1 Trial: A Phase I Study of Genetespib in Combination with Chemoradiation for Stage II-III Esophageal Carcinoma |
| Funding Source: | Synta Pharmaceuticals |
| Role: | PI |
| Date: | 2015 - 2017 |
| Title: | Diffusion-Weighted Magnetic Reasonance Imaging for Early Response Assessment of Neoadjuvant Chemoradiation Therapy in patients with Esophgeal Carcinoma |
| Funding Source: | UTMDACC |
| Role: | CO-I |
| ID: | Sister Institution Network Fund Application |
| Date: | 2014 - 2019 |
| Title: | Targeting the Tumor Microenvironment in NSCLC |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | 5P50CA709007 |
| Date: | 2014 - 2019 |
| Title: | Improving the Clinical Effectiveness and Understanding of the Biophysical Basis- Project 1: Assessment of Effectiveness of IMPT vs. IMRT through Phase II Randomized Clinical Trials |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | 5U19CA021239 |
| Date: | 2014 - 2017 |
| Title: | Mapping Proton RBE Variability Using Automated Biology and Monte Carlo Techniques |
| Funding Source: | NIH/NCI |
| Role: | CO-I |
| ID: | 1-R21-CA187484-01 |
| Date: | 2014 - 2016 |
| Title: | Radiogenomic Predictor of Pathologic Response and Recurrence in Esophageal Cancer Patients |
| Funding Source: | R. Lee Clark Fellowship |
| Role: | PI |
| Date: | 2013 - 2018 |
| Title: | Phase I Trial Combining Trametinib with Chemoradiation in Kras Mutant Lung Cancer |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Date: | 2013 - 2017 |
| Title: | Research and Development of Novel Radiation Sensitizers |
| Funding Source: | STCube Pharmaceuticals Inc |
| Role: | PI |
| Date: | 2013 - 2015 |
| Title: | Transcriptomic Correlates of Pathologic Complete Response and Residual Disease after Neoadjuvant Chemoradiation in Esophageal Cancer |
| Funding Source: | MD Anderson Cancer Center |
| Role: | PI |
| Date: | 2013 - 2015 |
| Title: | Functional Magnetic Resonance Imaging for Response Assessment to Chemoradiation in Esophageal Cancer |
| Funding Source: | Elekta LLC |
| Role: | PI |
| Date: | 2013 - 2015 |
| Title: | High Throughput Synthetic Lethal Drug Screen to Identify Novel Radiation Sensitizers for Kras Mutant Non-Small Cell Lung Cancer |
| Funding Source: | MD Anderson Cancer Center |
| Role: | PI |
| ID: | UTMDACC IRG – Basic Research |
| Date: | 2013 - 2015 |
| Title: | Kras Mutation Targeting to Enhance Radiation Response in Non-Small Cell Lung Cancer |
| Funding Source: | Uniting Against Lung Cancer |
| Role: | PI |
| ID: | Young Investigator Grant |
Selected Publications
Peer-Reviewed Articles
- Wang, K, Ye, R, Bai, S, Xiao, Z, Yang, L, Li, J, Tang, C, Sei, E, Peng, J, Casasent, A, Lin, SH, Nagi, C, Thompson, A, Krishnamurthy, S, Navin, N. Coalescing single-cell genomes and transcriptomes to decode breast cancer progression. Cell 188(22):6355-6369.e16, 2025. e-Pub 2025. PMID: 40912251.
- Adams, DL, Cristofanilli, M, Lin, SH, Bergan, RC, Ho, TH, Marks, JR, Martin, SS, Edelman, MJ, Chumsri, S, Hager, EJ, Tang, CM, Tsai, S, Alpaugh, RK. Phenotyping and clinical utility of phagocytic polyploid giant cancer macrophages in blood. Cancer Letters 631, 2025. e-Pub 2025. PMID: 40912599.
- Grippin AJ, Marconi C, Copling S, Li N, Braun C, Woody C, Young E, Gupta P, Wang M, Wu A, Jeong SD, Soni D, Weidert F, Xie C, Goldenberg E, Kim A, Zhao C, DeVries A, Castillo P, Lohray R, Rooney MK, Schrank BR, Wang Y, Ma Y, Chang E, Kouzy R, Dyson K, Jafarnia J, Nariman N, Gladish G, New J, Argueta A, Amaya D, Thomas N, Doty A, Chen J, Copling N, Alatrash G, Simon J, Davies AB, Dennis W, Liang R, Lewis J, Wei X, Rinsurongkawong W, Vaporciyan AA, Johns A, Team D, Lee J, Lee J, Sun R, Sharma P, Tran H, Zhang J, Gibbons DL, Wargo J, S Kim BY, Heymach JV, Mendez-Gomez HR, Jiang W, Sayour EJ, Lin SH. SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade. Nature 647(8089):488-497, 2025. e-Pub 2025. PMID: 41125896.
- Lin, SH, Subbiah, V, Cohen, E, Li, Z, Lu, YJ, Son, YL, Lyu, Y, Gao, H, Jayachandran, G, Neri, S, Sharma, A, Fang, PQ, Karp, DD, Hong, DS, Rodon Ahnert, J, Yu, H, Peng, J, Lloyd, GK, Tonra, JR, Reuben, JM, Huang, L, Fu, S. Plinabulin following radiation enhances dendritic cell maturation and checkpoint inhibitor retreatment of relapsed/refractory cancers. Med 6(10), 2025. e-Pub 2025. PMID: 40580957.
- Saad, M, Showkatian, E, Verma, V, Al Tashi, Q, Aminu, M, Xu, X, Mohamed, MQ, Salehjahromi, M, Sujit, S, Kitsel, Y, Lin, SH, Liao, Z, Gandhi, S, Qian, DC, Jaffray, D, Chung, C, Vokes, N, Zhang, J, Jack Lee, J, Heymach, JV, Wu, J, Chang, JY. Causal AI-based clinical and radiomic analysis for optimizing patient selection in combined immunotherapy and SABR in early-stage NSCLC. Journal for immunotherapy of cancer 13(10), 2025. e-Pub 2025. PMID: 41052882.
- Ahn M, Lin SH, Yang C, Lee JB, Neal JW, Okishio K, Nishino K, Smith D, Rauter M, Jimenez M, Nasirova F, Kim Y. Mutation testing, treatment patterns, and outcomes in patients with unresectable stage III EGFR-mutated non-small cell lung cancer treated with chemoradiotherapy: Final analysis of a global real-world study. Lung Cancer 209, 2025. e-Pub 2025. PMID: 41151357.
- Moding, EJ, Esfahani, MS, Jin, C, Hui, AB, Nabet, BY, Liu, Y, Chabon, JJ, Binkley, MS, Kurtz, DM, Hamilton, EG, Chaudhuri, AA, Liu, CL, Li, Z, Bonilla, RF, Jiang, AL, Lau, B, Lopez, PB, He, J, Qiao, Y, Xu, T, Yao, L, Gandhi, S, Liao, Z, Das, M, Ramchandran, K, Padda, SK, Neal, JW, Wakelee, HA, Gensheimer, MF, Loo, BW, Li, R, Lin, SH, Alizadeh, AA, Diehn, M. Integrating ctDNA Analysis and Radiomics for Dynamic Risk Assessment in Localized Lung Cancer. Cancer discovery 15(8):1609-1629, 2025. e-Pub 2025. PMID: 40299851.
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- Chun SG, Liao Z, Jeter MD, Chang JY, Lin SH, Komaki RU, Guerrero TM, Mayo RC, Korah BM, Koshy SM, Heymach JV, Koong AC, Skinner HD. Metabolic Responses to Metformin in Inoperable Early-stage Non-Small Cell Lung Cancer Treated With Stereotactic Radiotherapy: Results of a Randomized Phase II Clinical Trial. Am J Clin Oncol 43(4):232-235, 2020. e-Pub 2020.
- Yang L, Shen C, Pettit CJ, Li T, Hu AJ, Miller ED, Zhang J, Lin SH, Williams TM. Wee1 Kinase Inhibitor AZD1775 Effectively Sensitizes Esophageal Cancer to Radiotherapy. Clin Cancer Res, 2020. e-Pub 2020. PMID: 32220892.
- Lin SH, Lin Y, Yao L, Kalhor N, Carter BW, Altan M, Blumenschein G, Byers LA, Fossella F, Gibbons DL, Kurie JM, Lu C, Simon G, Skoulidis F, Chang JY, Jeter MD, Liao Z, Gomez DR, O'Reilly M, Papadimitrakopoulou V, Thall P, Heymach JV, Tsao AS. Phase II Trial of Concurrent Atezolizumab With Chemoradiation for Unresectable NSCLC. J Thorac Oncol 15(2):248-257, 2020. e-Pub 2020.
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- Lei G, Zhang Y, Koppula P, Liu X, Zhang J, Lin SH, Ajani JA, Xiao Q, Liao Z, Wang H, Gan B. The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression. Cell Res, 2020. e-Pub 2020.
- Borggreve AS, Goense L, van Rossum PSN, Heethuis SE, van Hillegersberg R, Lagendijk JJW, MGEH L, ALHMW VL, Mook S, Ruurda JP, van Vulpen M, Voncken FEM, Aleman BMP, Bartels-Rutten A, Ma J, Fang P, Musall BC, Lin SH, Meijer GJ. Preoperative Prediction of Pathologic Response to Neoadjuvant Chemoradiotherapy in Patients With Esophageal Cancer Using 18F-FDG PET/CT and DW-MRI: A Prospective Multicenter Study. Int J Radiat Oncol Biol Phys 106(5):998-1009, 2020. e-Pub 2020.
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- Pataer A, Ozpolat B, Shao R, Cashman NR, Plotkin SS, Samuel CE, Lin SH, Kabil NN, Wang J, Majidi M, Fang B, Roth JA, Vaporciyan AA, Wistuba II, Hung MC, Swisher SG. Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells. Oncogene 39(4):801-813, 2020. e-Pub 2020.
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- van Rossum PSN, Deng W, Routman DM, Liu AY, Xu C, Shiraishi Y, Peters M, Merrell KW, Hallemeier CL, Mohan R, Lin SH. Prediction of severe lymphopenia during chemoradiotherapy for esophageal cancer: development and validation of a pretreatment nomogram. Pract Radiat Oncol 10(1):16-26, 2020. e-Pub 2020. PMID: 31369887.
- Abe RJ, Savage H, Imanishi M, Banerjee P, Kotla S, Paez-Mayorga J, Taunton J, Fujiwara K, Won JH, Yusuf SW, Palaskas NL, Banchs J, Lin SH, Schadler KL, Abe JI, Le NT. p90RSK-MAGI1 Module Controls Endothelial Permeability by Post-translational Modifications of MAGI1 and Hippo Pathway. Front Cardiovasc Med 7:542485, 2020. e-Pub 2020. PMID: 33304925.
- Thomas M, Defraene G, Lambrecht M, Deng W, Moons J, Nafteux P, Lin SH, Haustermans K. NTCP model for postoperative complications and one-year mortality after trimodality treatment in oesophageal cancer. Radiother Oncol 141:33-40, 2019. e-Pub 2019.
- Veeranki OL, Tong Z, Mejia A, Verma A, Katkhuda R, Bassett R, Kim TB, Wang J, Lang W, Mino B, Solis L, Kingsley C, Norton W, Tailor R, Wu JY, Krishnan S, Lin SH, Blum M, Hofstetter W, Ajani J, Kopetz S, Maru D. A novel patient-derived orthotopic xenograft model of esophageal adenocarcinoma provides a platform for translational discoveries. Dis Model Mech 12(12), 2019. e-Pub 2019.
- Venkatesulu BP, Sharma A, Pollard-Larkin JM, Sadagopan R, Symons J, Neri S, Singh PK, Tailor R, Lin SH, Krishnan S. Ultra high dose rate (35 Gy/sec) radiation does not spare the normal tissue in cardiac and splenic models of lymphopenia and gastrointestinal syndrome. Sci Rep 9(1):17180, 2019. e-Pub 2019.
- Azad TD, Chaudhuri AA, Fang P, Qiao Y, Esfahani MS, Chabon JJ, Hamilton EG, Yang YD, Lovejoy A, Newman AM, Kurtz DM, Jin M, Schroers-Martin J, Stehr H, Liu CL, Hui AB, Patel V, Maru D, Lin SH, Alizadeh AA, Diehn M. Circulating Tumor DNA Analysis for Detection of Minimal Residual Disease After Chemoradiotherapy for Localized Esophageal Cancer. Gastroenterology, 2019. e-Pub 2019.
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- Li N, Wang Y, Neri S, Zhen Y, Fong LW, Qiao Y, Li X, Chen Z, Stephan C, Deng W, Ye R, Jiang W, Zhang S, Yu Y, Hung MC, Chen J, Lin SH. Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling. Nat Commun 10(1):4363, 2019. e-Pub 2019.
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- Goense L, Lin SH. ASO Author Reflections: Predicting Early Recurrence After Trimodality Therapy for Esophageal Adenocarcinoma. Ann Surg Oncol, 2018. e-Pub 2018. PMID: 30443832.
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- Goense L, Ruurda JP, Carter BW, Fang P, Ho L, Meijer GJ, van Hillegersberg R, Hofstetter WL, Lin SH. Prediction and diagnosis of interval metastasis after neoadjuvant chemoradiotherapy for oesophageal cancer using 18F-FDG PET/CT. Eur J Nucl Med Mol Imaging 45(10):1742-1751, 2018. e-Pub 2018. PMID: 29663014.
- Fang P, Jiang W, Davuluri R, Xu C, Krishnan S, Mohan R, Koong AC, Hsu CC, Lin SH. High lymphocyte count during neoadjuvant chemoradiotherapy is associated with improved pathologic complete response in esophageal cancer. Radiother Oncol 128(3):584-590, 2018. e-Pub 2018. PMID: 29530432.
- Xi M, Hallemeier CL, Merrell KW, Liao Z, Murphy MAB, Ho L, Hofstetter WL, Mehran R, Lee JH, Bhutani MS, Weston B, Maru DM, Komaki R, Ajani JA, Lin SH. Recurrence Risk Stratification After Preoperative Chemoradiation of Esophageal Adenocarcinoma. Ann Surg 268(2):289-295, 2018. e-Pub 2018. PMID: 28628563.
- Suzuki R, Wei X, Allen PK, Welsh JW, Cox JD, Komaki R, Lin SH. Twice-daily Thoracic Radiotherapy for Limited-stage Small-cell Lung Cancer Does Not Increase the Incidence of Acute Severe Esophagitis. Clin Lung Cancer, 2018. e-Pub 2018. PMID: 30197263.
- Wang Y, Li N, Jiang W, Deng W, Ye R, Xu C, Qiao Y, Sharma A, Zhang M, Hung MC, Lin SH. Mutant LKB1 Confers Enhanced Radiosensitization in Combination with Trametinib in KRAS-Mutant Non-Small Cell Lung Cancer. Clin Cancer Res, 2018. e-Pub 2018. PMID: 30068711.
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- Goense L, Merrell KW, Arnett AL, Hallemeier CL, Meijer GJ, Ruurda JP, Hofstetter WL, van Hillegersberg R, Lin SH. Validation of a Nomogram Predicting Survival After Trimodality Therapy for Esophageal Cancer. Ann Thorac Surg, 2018. e-Pub 2018. PMID: 29932887.
- Goense L, van Rossum PSN, Xi M, Maru DM, Carter BW, Meijer GJ, Ho L, van Hillegersberg R, Hofstetter WL, Lin SH. Preoperative Nomogram to Risk Stratify Patients for the Benefit of Trimodality Therapy in Esophageal Adenocarcinoma. Ann Surg Oncol 25(6):1598-1607, 2018. e-Pub 2018. PMID: 29569125.
- Verma V, Moreno AC, Haque W, Fang P, Lin SH. Sequential Versus Concurrent Chemoradiation Therapy by Surgical Margin Status in Resected Non-Small Cell Lung Cancer. J Natl Compr Canc Netw 16(5):508-516, 2018. e-Pub 2018. PMID: 29752325.
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- Moreno AC, Haque W, Verma V, Fang P, Lin SH. Concurrent Versus Sequential Chemoradiation Therapy in Completely Resected Pathologic N2 Non-Small Cell Lung Cancer: Propensity-Matched Analysis of the National Cancer Data Base. Ann Surg Oncol 25(5):1245-1253, 2018. e-Pub 2018. PMID: 29484562.
- McGrail DJ, Federico L, Li Y, Dai H, Lu Y, Mills GB, Yi S, Lin SH, Sahni N. Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers. Nat Commun 9(1):1317, 2018. e-Pub 2018. PMID: 29615613.
- Prayongrat A, Umegaki K, van der Schaaf A, Koong AC, Lin SH, Whitaker T, McNutt T, Matsufuji N, Graves E, Mizuta M, Ogawa K, Date H, Moriwaki K, Ito YM, Kobashi K, Dekura Y, Shimizu S, Shirato H. Present developments in reaching an international consensus for a model-based approach to particle beam therapy. J Radiat Res 59(suppl_1):i72-i76, 2018. e-Pub 2018. PMID: 29529229.
- Fang P, Musall BC, Son JB, Moreno AC, Hobbs BP, Carter BW, Fellman BM, Mawlawi O, Ma J, Lin SH. Multimodal Imaging of Pathologic Response to Chemoradiation in Esophageal Cancer. Int J Radiat Oncol Biol Phys, 2018. e-Pub 2018. PMID: 29685377.
- Barua S, Fang P, Sharma A, Fujimoto J, Wistuba I, Rao AUK, Lin SH. Spatial interaction of tumor cells and regulatory T cells correlates with survival in non-small cell lung cancer. Lung Cancer, 2018. e-Pub 2018.
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- Xi M, Liao Z, Hofstetter WL, Komaki R, Ho L, Lin SH. (18)F-FDG PET Response After Induction Chemotherapy Can Predict Who Will Benefit from Subsequent Esophagectomy After Chemoradiotherapy for Esophageal Adenocarcinoma. J Nucl Med 58(11):1756-1763, 2017. e-Pub 2017. PMID: 28522744.
- Verma V, Allen PK, Simone CB, Gay HA, Lin SH. Association of Treatment at High-Volume Facilities With Survival in Patients Receiving Chemoradiotherapy for Nasopharyngeal Cancer. JAMA Otolaryngol Head Neck Surg, 2017. e-Pub 2017. PMID: 29098291.
- Xi M, Yang Y, Zhang L, Yang H, Merrell KW, Hallemeier CL, Shen RK, Haddock MG, Hofstetter WL, Maru DM, Ho L, Wu CC, Liu M, Lin SH, . Multi-institutional analysis of recurrence and survival after neoadjuvant chemoradiotherapy of esophageal cancer: The impact of histology on recurrence patterns and outcomes. Ann Surg 99(3):667-676, 2017. e-Pub 2017.
- Blum Murphy M, Xiao L, Patel VR, Maru DM, Correa AM, G Amlashi F, Liao Z, Komaki R, Lin SH, Skinner HD, Vaporciyan A, Walsh GL, Swisher SG, Sepesi B, Lee JH, Bhutani MS, Weston B, Hofstetter WL, Ajani JA. Pathological complete response in patients with esophageal cancer after the trimodality approach: The association with baseline variables and survival-The University of Texas MD Anderson Cancer Center experience. Cancer 123(21):4106-4113, 2017. e-Pub 2017. PMID: 28885712.
- Xi M, Xu C, Liao Z, Chang JY, Gomez DR, Jeter M, Cox JD, Komaki R, Mehran R, Blum-Murphy M, Hofstetter WL, Maru DM, Bhutani MS, Lee JH, Weston B, Ajani AA, Lin SH, . Comparative Outcomes after Definitive Chemoradiotherapy using Proton Beam Therapy versus Intensity-Modulated Radiation Therapy for Esophageal Cancer: A Retrospective Single-Institutional Analysis. Int J Radiat Oncol Biol Phys 99(3):667-676, 2017. e-Pub 2017.
- Verma V, Allen PK, Simone CB, Gay HA, Lin SH. Addition of Definitive Radiotherapy to Chemotherapy in Patients With Newly Diagnosed Metastatic Nasopharyngeal Cancer. J Natl Compr Canc Netw 15(11):1383-1391, 2017. e-Pub 2017. PMID: 29118230.
- An Y, Jiang W, Kim BYS, Qian JM, Tang C, Fang P, Logan J, D'Souza NM, Haydu LE, Wang XA, Hess KR, Kluger H, Glitza IC, Mahajan A, Welsh JW, Lin SH, Yu JB, Davies MA, Hwu P, Sulman EP, Brown PD, Chiang VLS, Li J. Stereotactic radiosurgery of early melanoma brain metastases after initiation of anti-CTLA-4 treatment is associated with improved intracranial control. Radiother Oncol 125(1):80-88, 2017. e-Pub 2017. PMID: 28916225.
- Xi M, Lin SH. Prognostic and Predictive Value of FDG-PET as an Aid in Oesophageal Cancer Management. European Medical Journal:78-84, 2017. e-Pub 2017.
- Wang Y, Gudikote J, Giri U, Yan J, Deng W, Ye R, Jiang W, Li N, Hobbs B, Wang J, Swisher SG, Fujimoto J, Wistuba II, Komaki R, Heymach J, Lin SH. RAD50 expression is associated with poor clinical outcomes after radiotherapy for resected non-small cell lung cancer. Clin Cancer Res, 2017. e-Pub 2017. PMID: 29030353.
- Adams DL, Adams DK, He J, Kalhor N, Zhang M, Xu T, Gao H, Reuben JM, Qiao Y, Komaki R, Liao Z, Edelman MJ, Tang CM, Lin SH. Sequential tracking of PD-L1 expression and RAD50 induction in circulating tumor and stromal cells of lung cancer patients undergoing radiotherapy. Clin Cancer Res 23(19):5948-5958, 2017. e-Pub 2017. PMID: 28679765.
- Goense L, Heethuis SE, van Rossum PSN, Voncken FEM, Lagendijk JJW, MGEH L, Terhaard CH, van Hillegersberg R, Ruurda JP, Mook S, ALHMW VL, Lin SH, Meijer GJ. Correlation between functional imaging markers derived from diffusion-weighted MRI and 18F-FDG PET/CT in esophageal cancer. Nucl Med Commun, 2017. e-Pub 2017. PMID: 29023336.
- Shiraishi Y, Xu C, Yang J, Komaki R, Lin SH. Dosimetric comparison to the heart and cardiac substructure in a large cohort of esophageal cancer patients treated with proton beam therapy or Intensity-modulated radiation therapy. Radiother Oncol 125(1):48-54, 2017. e-Pub 2017. PMID: 28917586.
- Xi M, Liao Z, Deng W, Komaki R, Ho L, Lin SH. Recursive Partitioning Analysis Identifies Pretreatment Risk Groups for the Utility of Induction Chemotherapy Before Definitive Chemoradiation Therapy in Esophageal Cancer. Int J Radiat Oncol Biol Phys 99(2):407-416, 2017. e-Pub 2017. PMID: 28871991.
- Zhao L, Zhou Y, Pan H, Yin Y, Chai G, Mu Y, Xiao F, Lin SH, Shi M. Radiotherapy Alone or Concurrent Chemoradiation for Esophageal Squamous Cell Carcinoma in Elderly Patients. J Cancer 8(16):3242-3250, 2017. e-Pub 2017.
- Prayongrat A, Xu C, Li H, Lin SH, . Clinical outcomes of intensity-modulated proton therapy and concurrent chemotherapy in esophageal carcinoma: a single institutional experience. Advances in Radiation Oncology 2(301-307), 2017. e-Pub 2017.
- Kris MG, Gaspar LE, Chaft JE, Kennedy EB, Azzoli CG, Ellis PM, Lin SH, Pass HI, Seth R, Shepherd FA, Spigel DR, Strawn JR, Ung YC, Weyant M. Adjuvant Systemic Therapy and Adjuvant Radiation Therapy for Stage I to IIIA Completely Resected Non-Small-Cell Lung Cancers: American Society of Clinical Oncology/Cancer Care Ontario Clinical Practice Guideline Update. J Clin Oncol 35(25):2960-2974, 2017. e-Pub 2017. PMID: 28437162.
- Davuluri R, Jiang W, Fang P, Xu C, Komaki R, Gomez DR, Welsh J, Cox JD, Crane CH, Hsu CC, Lin SH. Lymphocyte Nadir and Esophageal Cancer Survival Outcomes After Chemoradiation Therapy. Int J Radiat Oncol Biol Phys 99(1):128-135, 2017. e-Pub 2017. PMID: 28816138.
- Xi, M, Xu, C, Liao, Z, Hofstetter, WL, Blum Murphy, M, Maru, DM, Bhutani, M, Lee, JH, Weston, B, Komaki, R, Lin, SH. The impact of histology on recurrence patterns in esophageal cancer treated with definitive chemoradiotherapy. Radiotherapy and Oncology 124(2):318-324, 2017. e-Pub 2017. PMID: 28687396.
- Kono M, Allen PK, Lin SH, Wei X, Jeter M, Welsh JW, Cox JD, Komaki R. Incidence of Second Malignancy after Successful Treatment of Limited-Stage Small-Cell Lung Cancer and Its Effects on Survival. J Thorac Oncol, 2017. e-Pub 2017.
- Chapple AG, Vannucci M, Thall PF, Lin SH. Bayesian variable selection for a semi-competing risks model with three hazard functions. Comput Stat Data Anal 112:170-185, 2017. e-Pub 2017. PMID: 29033478.
- Chang JY, Verma V, Li M, Zhang W, Komaki R, Lu C, Allen PK, Liao Z, Welsh J, Lin SH, Gomez D, Jeter M, O'Reilly M, Zhu RX, Zhang X, Li H, Mohan R, Heymach JV, Vaporciyan AA, Hahn S, Cox JD. Proton Beam Radiotherapy and Concurrent Chemotherapy for Unresectable Stage III Non-Small Cell Lung Cancer: Final Results of a Phase 2 Study. JAMA Oncol, 2017. e-Pub 2017.
- Verma V, Simone CB, Krishnan S, Lin SH, Yang J, Hahn SM. The Rise of Radiomics and Implications for Oncologic Management. J Natl Cancer Inst 109(7):1-3, 2017. e-Pub 2017. PMID: 28423406.
- Xu C, Xi M, Moreno A, Shiraishi Y, Hobbs BP, Huang M, Komaki R, Lin SH. Definitive Chemoradiation Therapy for Esophageal Cancer in the Elderly: Clinical Outcomes for Patients Exceeding 80 Years Old. Int J Radiat Oncol Biol Phys 98(4):811-819, 2017. e-Pub 2017. PMID: 28602412.
- Lester SC, Lin SH, Chuong M, Bhooshan N, Liao Z, Arnett AL, James SE, Evans JD, Spears GM, Komaki R, Haddock MG, Mehta MP, Hallemeier CL, Merrell KW. A Multi-institutional Analysis of Trimodality Therapy for Esophageal Cancer in Elderly Patients. Int J Radiat Oncol Biol Phys 98(4):820-828, 2017. e-Pub 2017. PMID: 28476435.
- Xu C, Lin SH. Deciding on the neoadjuvant approach for esophageal adenocarcinomas. J Thorac Dis 9(7):1818-1821, 2017. e-Pub 2017.
- Xi M, Lin SH. Recent advances in intensity modulated radiotherapy and proton therapy for esophageal cancer. Expert Rev Anticancer Ther 17(7):635-646, 2017. e-Pub 2017.
- Ho JC, Nguyen QN, Li H, Allen PK, Zhang X, Liao Z, Zhu XR, Gomez D, Lin SH, Gillin M, Komaki R, Hahn S, Chang JY. Reirradiation of Thoracic Cancers with Intensity Modulated Proton Therapy. Pract Radiat Oncol, 2017. e-Pub 2017. PMID: 28867546.
- Xu C, Xi M, Moreno A, Shiraishi Y, Hobbs B, Huang M, Komaki R, Lin SH. Clinical Outcomes of elderly patients with esophageal cancer treated with concurrent chemoradiotherapy. Int J Radiat Oncol Biol Phys 98(4):811-819, 2017. e-Pub 2017.
- Moreno AC, Verma V, Hofstetter WL, Lin SH. Patterns of Care and Treatment Outcomes of Elderly Patients With Stage I Esophageal Cancer: Analysis of the National Cancer Data Base. J Thorac Oncol 12(7):1152-1160, 2017. e-Pub 2017.
- Lin SH, Merrell KW, Shen J, Verma V, Correa AM, Wang L, Thall PF, Bhooshan N, James SE, Haddock MG, Suntharalingam M, Mehta M, Liao Z, Cox JD, Komaki R, Mehran R, Chuong MD, Hallemeier CL. Multi-institutional Analysis of Radiation Modality Use and Postoperative Outcomes of Neoadjuvant Chemoradiation for Esophageal Cancer. Radiother Oncol 123(3):376-381, 2017. e-Pub 2017.
- Xi M, Liao Z, Hofstetter WL, Komaki R, Ho L, Lin SH. Positron Emission Tomography Response After Induction Chemotherapy Can Predict Who Will Benefit From Subsequent Esophagectomy After Chemoradiotherapy for Esophageal Cancer. J Nucl Med, 2017. e-Pub 2017.
- No H, Kikut J, Garrison G, Sidiropoulos N, Leavitt B, Gentchos G, Lin SH, , Anker CJ. Active Surveillance for Elderly Stage IA Non-Small Cell Lung Cancer Patients. Int J Radiat Oncol Biol Phys 98(1):232, 2017. e-Pub 2017.
- Fang P, Swanick CW, Pezzi TA, Liao Z, Welsh J, Lin SH, Gomez DR. Outcomes and toxicity following high-dose radiation therapy in 15 fractions for non-small cell lung cancer. Pract Radiat Oncol, 2017. e-Pub 2017.
- Lan M, Xu T, Gomez DR, Jeter MD, Nguyen QN, Deng W, Lin SH, Komaki RU, Liao Z. Association Between LGALS3 Gene Polymorphisms and Survival in Non-Small Cell Lung Cancer Patients Treated With Definitive Radiation Therapy. Int J Radiat Oncol Biol Phys 98(1):249-250, 2017. e-Pub 2017.
- Shi A, Liao Z, Allen PK, Ho L, Murphy M, Maru DM, Swisher SG, Hofstetter WL, Mehran RJ, Cox JD, Komaki R, Lin SH. Long Term Survival and Toxicity Outcomes of Intensity-Modulated Radiation Therapy for the Treatment of Esophageal Cancer: A Large Single-Institutional Cohort Study. Advances in Radiation Oncology 2:316-324, 2017. e-Pub 2017.
- Tong Z, Chatterjee D, Deng D, Veeranki O, Mejia A, Ajani JA, Hofstetter W, Lin SH, Guha S, Kopetz S, Krishnan S, Maru D. Antitumor effects of cyclin dependent kinase 9 inhibition in esophageal adenocarcinoma. Oncotarget 8(17):28696-28710, 2017. e-Pub 2017. PMID: 28404924.
- Liu S, Anfossi S, Qiu B, Zheng Y, Cai M, Fu J, Yang H, Liu Q, Chen Z, Fu J, Liu M, Burks JK, Lin SH, Reuben J, Liu H. Prognostic Factors for Locoregional Recurrence in Patients with Thoracic Esophageal Squamous Cell Carcinoma Treated with Radical Two-Field Lymph Node Dissection: Results from Long-Term Follow-Up. Ann Surg Oncol 24(4):966-973, 2017. e-Pub 2017.
- Xu C, Xi M, Komaki R, Balter PA, Huang M, Hobbs BP, Wang L, Lin SH. Dosimetric and Clinical Outcomes After Volumetric Modulated arc Therapy for Carcinoma of the Thoracic Esophagus. Advances in Radiation Oncology 2:325-332, 2017. e-Pub 2017.
- Logan JK, Tang C, Liao Z, Lee JJ, Heymach JV, Swisher SG, Welsh JW, Zhang J, Lin SH, Gomez DR. Analysis of Factors Affecting Successful Clinical Trial Enrollment in the Context of Three Prospective, Randomized, Controlled Trials. Int J Radiat Oncol Biol Phys 97(4):770-777, 2017. e-Pub 2017. PMID: 28244413.
- Verma V, 2nd SC, Allen PK, Lin SH. Outcomes of Stereotactic Body Radiotherapy for T1-T2N0 Small Cell Carcinoma According to Addition of Chemotherapy and Prophylactic Cranial Irradiation: A Multicenter Analysis. Clin Lung Cancer, 2017. e-Pub 2017. PMID: 28408183.
- Xi M, Liao Z, Deng W, Xu C, Komaki R, Blum M, Hofstetter WL, Ho L, Lin SH. A Prognostic Scoring Model for the Utility of Induction Chemotherapy Prior to Neoadjuvant Chemoradiotherapy in Esophageal Cancer. J Thorac Oncol, 2017. e-Pub 2017.
- Zhao L, Zhou Y, Mu Y, Chai G, Xiao F, Tan L, Lin SH, , Shi M. Patterns of failure and clinical outcomes of definitive radiotherapy for cervical esophageal cancer. Oncotarget 8(13):21852-21860, 2017. e-Pub 2017.
- Verma V, Simone CB, Allen PK, Gajjar SR, Shah C, Zhen W, Harkenrider MM, Hallemeier CL, Jabbour SK, Matthiesen CL, Braunstein SE, Lee P, Dilling TJ, Allen BG, Nichols EM, Attia A, Zeng J, Biswas T, Paximadis P, Wang F, Walker JM, Stahl JM, Daly ME, Decker RH, Hales RK, Willers H, Videtic GMM, Mehta MP, Lin SH, . Multi-Institutional Experience of Stereotactic Ablative Radiation Therapy for Stage I Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys 97(2):362-371, 2017. e-Pub 2017. PMID: 28011047.
- Swanick CW, Allen PK, Tao R, Olanrewaju AM, Sutton JR, Lin SH, Welsh J, Das P, Chang JY, Crane CH, Gomez DR. Incidence and predictors of chest wall toxicity after high-dose radiation therapy in 15 fractions. Pract Radiat Oncol 7(1):63-71, 2017. e-Pub 2017.
- van Rossum PS, Fried DV, Zhang L, Hofstetter WL, Ho L, Meijer GJ, Carter BW, Court LE, Lin SH. The value of (18)F-FDG PET before and after induction chemotherapy for the early prediction of a poor pathologic response to subsequent preoperative chemoradiotherapy in oesophageal adenocarcinoma. Eur J Nucl Med Mol Imaging 44(1):71-80, 2017. e-Pub 2017. PMID: 27511188.
- Verma V, Allen PK, Lin SH. Evaluating Factors for Prophylactic Feeding Tube Placement in Gastroesophageal Cancer Patients Undergoing Chemoradiotherapy. Front Oncol 7:235, 2017. e-Pub 2017. PMID: 29021972.
- Wang Y, Liu H, Diao L, Potter A, Zhang J, Qiao Y, Wang J, Proia DA, Tailor R, Komaki R, Lin SH, . Hsp90 Inhibitor Ganetespib Sensitizes Non-Small Cell Lung Cancer to Radiation but Has Variable Effects with Chemoradiation. Clin Cancer Res 22(23):5876-5886, 2016. e-Pub 2016. PMID: 27354472.
- Verma V, Moreno AC, Lin SH, . Advances in Radiotherapy Management of Esophageal Cancer. J Clin Med 21(5):1-11, 2016. e-Pub 2016.
- He L, Chapple A, Liao Z, Komaki R, Thall PF, Lin SH. Bayesian regression analyses of radiation modality effects on pericardial and pleural effusion and survival in esophageal cancer. Radiother Oncol 121(1):70-74, 2016. e-Pub 2016. PMID: 27562616.
- Wang L, Hoogcarspel SJ, Wen Z, van Vulpen M, Molkentine DP, Kok J, Lin SH, Broekhuizen R, Ang KK, Bovenschen N, Raaymakers BW, Frank SJ. Biological responses of human solid tumor cells to X-ray irradiation within a 1.5-Tesla magnetic field generated by a magnetic resonance imaging-linear accelerator. Bioelectromagnetics 37(7):471-480, 2016. e-Pub 2016.
- Wang L, Hoogcarspel SJ, Wen Z, van Vulpen M, Molkentine DP, Kok J, Lin SH, Broekhuizen R, Ang KK, Bovenschen N, Raaymakers BW, Frank SJ. Biological responses of human solid tumor cells to X-ray irradiation within a 1.5-Tesla magnetic field generated by a magnetic resonance imaging-linear accelerator. Bioelectromagnetics 37(7):471-80, 2016. e-Pub 2016. PMID: 27434783.
- Verma V, Lin SH, , 2nd SC, Mehta MP. Clinical outcomes and toxicities of proton radiotherapy for gastrointestinal neoplasms: a systematic review. J Gastrointest Oncol 7(4):644-664, 2016. e-Pub 2016.
- Lin SH, Hallemeier CL, Chuong M. Proton beam therapy for the treatment of esophageal cancer. Chin Clin Oncol 5(4):53, 2016. e-Pub 2016.
- Zhao L, Zhou S, Balter P, Shen C, Gomez DR, Welsh JD, Lin SH, Chang JY. Planning Target Volume D95 and Mean Dose Should Be Considered for Optimal Local Control for Stereotactic Ablative Radiation Therapy. Int J Radiat Oncol Biol Phys 95(4):1226-1235, 2016. e-Pub 2016.
- van Rossum PS, Fried DV, Zhang L, Hofstetter WL, van Vulpen M, Meijer GJ, Court LE, Lin SH. The Incremental Value of Subjective and Quantitative Assessment of 18F-FDG PET for the Prediction of Pathologic Complete Response to Preoperative Chemoradiotherapy in Esophageal Cancer. J Nucl Med 57(5):691-700, 2016. e-Pub 2016. PMID: 26795288.
- Li N, Feng L, Liu H, Wang J, Kasembeli M, Tran MK, Tweardy DJ, Lin SH, Chen J. PARP Inhibition Suppresses Growth of EGFR-Mutant Cancers by Targeting Nuclear PKM2. Cell Rep, 2016. e-Pub 2016. PMID: 27149849.
- Lin SH, Zhang N, Godby J, Wang J, Marsh GD, Liao Z, Komaki R, Ho L, Hofstetter WL, Swisher SG, Mehran RJ, Buchholz TA, Elting LS, Giordano SH. Radiation modality use and cardiopulmonary mortality risk in elderly patients with esophageal cancer. Cancer 122(6):917-928, 2016. e-Pub 2016. PMID: 26716915.
- Yu J, Zhang X, Liao L, Li H, Zhu R, Park PC, Sahoo N, Gillin M, Li Y, Chang JY, Komaki R, Lin SH. Motion-robust intensity modulated proton therapy for distal esophageal cancer. Med Phys 43(3):1111, 2016. e-Pub 2016. PMID: 26936698.
- Wang XS, Shi Q, Williams LA, Komaki R, Gomez DR, Lin SH, Chang JY, O'Reilly MS, Bokhari RH, Cox JD, Mohan R, Cleeland CS, Liao Z. Prospective Study of Patient-Reported Symptom Burden in Patients With Non-Small-Cell Lung Cancer Undergoing Proton or Photon Chemoradiation Therapy. J Pain Symptom Manage, 2016. e-Pub 2016. PMID: 26891607.
- Hobbs BP, Thall PF, Lin SH. Bayesian Group Sequential Clinical Trial Design using Total Toxicity Burden and Progression-Free Survival. J R Stat Soc Ser C Appl Stat 65(2):273-297, 2016. e-Pub 2016. PMID: 27034510.
- Foy JP, Pickering CR, Papadimitrakopoulou VA, Jelinek J, Lin SH, William WN, Frederick MJ, Wang J, Lang W, Feng L, Zhang L, Kim ES, Fan YH, Hong WK, El-Naggar AK, Lee JJ, Myers JN, Issa JP, Lippman SM, Mao L, Saintigny P. New DNA methylation markers and global DNA hypomethylation are associated with oral cancer development. Cancer Prev Res (Phila) 8(11):1027-1035, 2015. e-Pub 2015. PMID: 26342026.
- van Rossum PS, van Lier AL, van Vulpen M, Reerink O, Lagendijk JJ, Lin SH, van Hillegersberg R, Ruurda JP, Meijer GJ, Lips IM. Diffusion-weighted magnetic resonance imaging for the prediction of pathologic response to neoadjuvant chemoradiotherapy in esophageal cancer. Radiother Oncol 115(2):163-170, 2015. e-Pub 2015. PMID: 26002307.
- Swanick CW, Lin SH, Sutton J, Naik NS, Allen PK, Levy LB, Liao Z, Welsh JW, Komaki R, Chang JY, Gomez DR. Use of Simultaneous Radiation Boost Achieves High Control Rates in Patients With Non-Small-Cell Lung Cancer Who Are Not Candidates for Surgery or Conventional Chemoradiation. Clin Lung Cancer 16(2):156-163, 2015. e-Pub 2015. PMID: 25467928.
- Wang J, Milton DR, He L, Komaki R, Liao Z, Crane CH, Minsky BD, Thall PF, Lin SH. Comparison of Locoregional versus Extended Locoregional Radiation Volumes for Patients with Nonmetastatic Gastro-esophageal Junction Carcinomas. J Thorac Oncol 10(3):518-526, 2015. e-Pub 2015. PMID: 25695222.
- Lin SH, Wang J, Allen PK, Correa AM, Maru D, Swisher SG, Hofstetter WL, Liao Z, Ajani JA. Nomogram for Pathologic Complete Response to Neoadjuvant Chemoradiation also Predicts Survival Outcomes after Definitive Chemoradiation for Esophageal Cancer. J Gastrointest Oncol 6(1):45-52, 2015. e-Pub 2015. PMID: 25642337.
- Wang J, Palmer M, Bilton SD, Khoi VN, Greer S, Frame R, Liao Z, Komaki R, Cox JD, Lin SH. Comparing Proton Beam to Intensity Modulated Radiation Therapy Planning in Esophageal Cancer. Int J Particle Ther, 2015. e-Pub 2015.
- Guan F, Bronk L, Titt U, Lin SH, Mirkovic D, Kerr MD, Zhu XR, Dinh J, Sobieski M, Stephan C, Peeler CR, Taleei R, Mohan R, Grosshans DR. Spatial mapping of the biologic effectiveness of scanned particle beams: towards biologically optimized particle therapy. Sci Rep 5(9850):1-10, 2015. e-Pub 2015. PMID: 25984967.
- He LR, Qiao W, Liao ZX, Komaki R, Ho L, Hofstetter WL, Lin SH. Impact of comorbidities and use of common medications on cancer and non-cancer specific survival in esophageal carcinoma. BMC Cancer 15(111):1095, 2015. e-Pub 2015. PMID: 25777421.
- Xu T, Liao Z, O'Reilly MS, Levy LB, Welsh JW, Wang LE, Lin SH, Komaki R, Liu Z, Wei Q, Gomez DR. Serum inflammatory miRNAs predict radiation esophagitis in patients receiving definitive radiochemotherapy for non-small cell lung cancer. Radiother Oncol 113(3):379-384, 2014. e-Pub 2014. PMID: 25466375.
- Lin SH, Wang J, Saintigny P, WuCC, Giri U, Zhang J, Menju T, Diao L, Byers L, Weinstein JN, Coombes KR, Girard L, Komaki R, Wistuba II, Date H, Minna JD, Heymach JV. Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition. BMC Genomics 15, 2014. e-Pub 2014. PMID: 25486910.
- Gomez DR, Yusuf SW, Munsell MF, Welsh JW, Liao Z, Lin SH, Pan HY, Chang JY, Komaki R, Cox JD, McAleer MF, Grosshans DR. Prospective exploratory analysis of cardiac biomarkers and electrocardiogram abnormalities in patients receiving thoracic radiation therapy with high-dose heart exposure. J Thorac Oncol 9(10):1551-60, 2014. e-Pub 2014. PMID: 25521400.
- Wang1 J, Court2 LE, Rao2 A, Bassett3 R, Lee1 JK, Hunter2 L, Myles1 B, Liao1 Z, and Lin SH. Textural Features on Computed Tomography Scans Predict Overall Survival in Patients with Esophageal Cancer. Nuclear Medicine & Radiation, 2014. e-Pub 2014.
- He L, Allen PK, Potter A, Wang J, Chang JY, Gomez DR, Komaki R, Liao Z, Lin SH. Re-evaluating the Optimal Radiation Dose for Definitive Chemoradiotherapy for Esophageal Squamous Cell Carcinoma. J Thorac Oncol 9(9):1398-1405, 2014. e-Pub 2014. PMID: 25122435.
- Patel VR, Hofstetter WL, Correa AM, Agarwal A, Rashid A, Bhutani MS, Lin SH, Ajani JA, Swisher SG, Maru DM. Signet Ring Cells in Esophageal Adenocarcinoma Predict Poor Response to Preoperative Chemoradiation. Ann Thorac Surg 98(3):1064-1071, 2014. e-Pub 2014. PMID: 25038008.
- Lin SH, Zhang J, Giri U, Stephan C, Sobieski M, Zhong L, Mason KA, Molkentine J, Thames HD, Yoo SS, Heymach JV. A High Content Clonogenic Survival Drug Screen Identifies MEK Inhibitors as Potent Radiation Sensitizers for KRAS Mutant Non-Small Cell Lung Cancer. J Thorac Oncol 9(7):965-973, 2014. e-Pub 2014. PMID: 24922006.
- Wang J, Suri JS, Allen PK, Liao Z, Komaki R, Ho L, Hofstetter WL, Lin SH. Factors Predictive of Improved Outcomes With Multimodality Local Therapy After Palliative Chemotherapy for Stage IV Esophageal Cancer. Am J Clin Oncol, 2014. e-Pub 2014. PMID: 24710122.
- Juloori A, Tucker SL, Komaki R, Liao Z, Correa AM, Swisher SG, Hofstetter WL, Lin SH. Influence of preoperative radiation field on postoperative leak rates in Esophageal cancer patients after trimodality therapy. J Thorac Oncol 9(4):534-540, 2014. e-Pub 2014. PMID: 24736077.
- Ly NB, Allen PK, Lin SH. Stereotactic body radiation therapy for stage I small cell lung cancer: a single institutional case series and review of the literature. J Radiat Oncol, 2014. e-Pub 2014.
- Wang J, Myles B, Wei C, Chang JY, Hofstetter WL, Ajani JA, Swisher SG, Cox JD, Komaki R, Liao Z, Lin SH. Obesity and outcomes in patients treated with chemoradiotherapy for Esophageal Carcinoma. Dis Esophagus 27(2):168-175, 2014. e-Pub 2014. PMID: 23621168.
- Yang Y, Ahn YH, Chen Y, Tan X, Guo L, Gibbons DL, Ungewiss C, Peng DH, Liu X, Lin SH, Thilaganathan N, Wistuba II, Rodriguez-Canales J, McLendon G, Creighton CJ, Kurie JM. ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism. J Clin Invest 124:2696-2708, 2014. e-Pub 2014.
- Zhang X, Lin SH, Fang B, Gillin M, Mohan R, Chang JY. Therapy resistant cancer stem cells have differing sensitivity to photon versus proton beam radiation. J Thorac Oncol 8(12):1484-1491, 2013. e-Pub 2013. PMID: 24389430.
- Wang J, Wei C, Tucker SL, Myles B, Palmer M, Hofstetter WL, Swisher SG, Ajani JA, Cox JD, Komaki R, Liao Z, Lin SH. Predictors of postoperative complications after trimodality therapy for esophageal cancer. Int J Radiat Oncol Biol Phys 86(5):885-891, 2013. e-Pub 2013. PMID: 23845841.
- Gomez DR, Gillin M, Liao Z, Wei C, Lin SH, Swanick C, Alvarado T, Komaki R, Cox JD, Chang JY. Phase 1 study of dose escalation in hypofractionated proton beam therapy for non-small cell lung cancer. Int J Radiat Oncol Biol Phys 86(4):665-70, 2013. e-Pub 2013.
- Skinner HD, McCurdy MR, Echeverria AE, Lin SH, Welsh JW, O'Reilly MS, Hofstetter WL, Ajani JA, Komaki R, Cox JD, Sandulache VC, Myers JN, Guerrero TM. Metformin use and improved response to therapy in esophageal adenocarcinoma. Acta Oncol 52(5):1002-1009, 2013. e-Pub 2013. PMID: 22950385.
- Wu CC, Kannan K, Lin SH, Yen L, Milosavlijevic A. Identification of cancer fusion drivers using network fusion centrality. Bioinformatics, 2013. e-Pub 2013.
- Cheedella NK, Suzuki A, Xiao L, Hofstetter WL, Maru DM, Taketa T, Sudo K, Blum MA, Lin SH, Welch J, Lee JH, Bhutani MS, Rice DC, Vaporciyan AA, Swisher SG, Ajani JA. Association between clinical complete response and pathological complete response after preoperative chemoradiation in patients with gastroesophageal cancer: analysis in a large cohort. Ann Oncol 24(5):1262-1266, 2013. e-Pub 2013. PMID: 23247658.
- Lin SH, George T, Ben-Josef E, Bradley J, Choe K, Edelman MJ, Guha C, Krishnan S, Lawrence T, Le QT, Lu B, Mehta M, Peereboom D, Sarkaria J, Seong J, Wang D, Welliver MX, Coleman N, Vikram B, Yoo S, Chung C. Opportunities and Challenges in the Era of Molecularly Targeted Agents and Radiation Therapy. J Natl Cancer Inst, 2013. e-Pub 2013.
- Lopez Guerra JL, Gomez DR, Lin SH, Levy LB, Zhuang Y, Komaki R, Jaen J, Vaporciyan AA, Swisher SG, Cox JD, Liao Z, Rice DC. Risk factors for local and regional recurrence in patients with resected N0-N1 non-small-cell lung cancer, with implications for patient selection for adjuvant radiation therapy. Ann Oncol 24(1):67-74, 2013. e-Pub 2013. PMID: 23002278.
- Armini A, Feiran L, Corea AM, Baldessare R, Rimner A, Huang J, Roth JA, Swisher SG, Vaporciyan AA, Lin SH. Predictors for locoregional recurrence for clinical stage III-N2 non-small cell lung cancer with nodal downstaging after induction chemotherapy and surgery. Ann Surg Oncol 20:1934-40, 2013. e-Pub 2013.
- Lin SH, Myles B, Wang L, Thall PF, Hofstetter WL, Swisher SG, Ajani JA, Cox JD, Komaki R, Liao Z. Propensity score based comparison of long term outcomes with 3D conformal radiotherapy (3DCRT) versus Intensity Modulated Radiation Therapy (IMRT) in treatment of esophageal cancer. Int J Radiat Oncol Biol Phy 84(5):1078-85, 2012. e-Pub 2012. PMID: 22867894.
- Hayashi Y, Xiao L, Suzuki A, Blum MA, Sabloff B, Taketa T, Maru DM, Welsh J, Lin SH, Weston B, Lee JH, Bhutani MS, Hofstetter WL, Swisher SG, Ajani JA. A nomogram associated with high probability of malignant nodes in the surgical specimen after trimodality therapy of patients with oesophageal cancer. Eur J Cancer 48(18):3396-33404, 2012. e-Pub 2012. PMID: 22853875.
- Saintigny P, Massarelli E, Lin SH, Ahn YH, Chen Y, Goswani S, Erez B. CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma. Cancer Research, 2012. e-Pub 2012.
- Ajani JA, Correa AM, Hofstetter WL, Rice DC, Blum MA, Suzuki A, Taketa T, Welsh J, Lin SH, Lee JH, Bhutani MS, Ross WA, Maru DM, Macapinlac HA, Erasmus J, Komaki R, Mehran RJ, Vaporciyan AA, Swisher SG. Clinical parameters model for predicting pathologic complete response following preoperative chemoradiation in patients with esophageal cancer. Ann Oncol 23(10):2638-2642, 2012. e-Pub 2012. PMID: 22831985.
- Xu T, Wei Q, Lopez Guerra JL, Wang LE, Liu Z, Gomez D, O'Reilly M, Lin SH, Zhuang Y, Levy LB, Mohan R, Zhou H, Liao Z. HSPB1 Gene Polymorphisms Predict Risk of Mortality for US Patients After Radio(chemo)therapy for Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys 84(2):e229-e235, 2012. e-Pub 2012. PMID: 22608953.
- Hayashi Y, Correa AM, Hofstetter WL, Vaporciyan AA, Mehran RJ, Rice DC, Suzuki A, Lee JH, Bhutani MS, Welsh J, Lin SH, Maru DM, Swisher SG, Ajani JA. Patients with high body mass index tend to have lower stage of esophageal carcinoma at diagnosis. Dis Esophagus 25(7):614-622, 2012. e-Pub 2012. PMID: 22150920.
- Guerra JLL, Gomez D, Zhuang Y, Hong D, Heymach JV, Swisher SG, Lin SH, Komaki R, Cox JD, Liao Z. Prognostic impact of radiation therapy to the primary site in non-small cell lung cancer patients with oligometastasis at diagnosis. Int J Radiat Oncol Biol Phy 84(1):e61-e67, 2012. e-Pub 2012. PMID: 22503522.
- Amini A, Correa AM, Komaki R, Chang JY, Tsao AS, Roth JA, Swisher SG, Rice DC, Vaporciyan AA, Lin SH. The role of consolidation therapy for stage III non-small cell lung cancer with persistent N2 disease after induction chemotherapy. Ann Thorac Surg 94(3):914-920, 2012. e-Pub 2012. PMID: 22819472.
- Lin SH, Komaki R, Liao Z, Wei C, Myles B, Guo X, Palmer M, Mohan R, Swisher SG, Hofstetter WL, Ajani JA, Cox JD. Proton beam therapy and concurrent chemotherapy for esophageal cancer. Int J Radiat Oncol Biol Phys 83(3):e345-e351, 2012. e-Pub 2012. PMID: 22417808.
- Yu ZH, Lin SH, Balter P, Zhang L, Dong L. A comparison of tumor motion characteristics between early stage and locally advanced stage lung cancers. Radiother Oncol 104(1):33-38, 2012. e-Pub 2012. PMID: 22677039.
- Wang J, Lin SH, Dong L, Balter P, Mohan R, Komaki R, Cox JD, Starkschall G. Quantifying the Interfractional Displacement of the Gastroesophageal Junction during Radiation Therapy for Esophageal Cancer. Int J Radiat Oncol Biol Phys 83(2):e273-e280, 2012. e-Pub 2012. PMID: 22440040.
- Taketa T, Correa AM, Suzuki A, Blum MA, Chien P, Lee JH, Welsh J, Lin SH, Maru DM, Erasmus JJ, Bhutani MS, Weston B, Rice DC, Vaporciyan AA, Hofstetter WL, Swisher SG, Ajani JA. Outcome of Trimodality-Eligible Esophagogastric Cancer Patients Who Declined Surgery after Preoperative Chemoradiation. Oncology 83(5):300-304, 2012. e-Pub 2012. PMID: 22964903.
- Suzuki A, Xiao L, Hayashi Y, Blum MA, Welsh JW, Lin SH, Lee JH, Bhutani MS, Weston B, Maru DM, Rice DC, Swisher SG, Hofstetter WL, Erasmus J, Ajani JA. Nomograms for prognostication of outcome in patients with esophageal and gastroesophageal carcinoma undergoing definitive chemoradiotherapy. Oncology 82(2):108-113, 2012. e-Pub 2012. PMID: 22328056.
- Joy S, Starkschall G, Kry S, Salehpour M, White RA, Lin SH, Balter P. Dosimetric effects of jaw tracking in step-and-shoot intensity-modulated radiation therapy. J Appl Clin Med Phys 13(2):3707, 2012. e-Pub 2012. PMID: 22402386.
- Amini A, Lin SH, Wei C, Allen P, Cox JD, Komaki R. Accelerated hypofractionated radiation therapy compared to conventionally fractionated radiation therapy for the treatment of inoperable non-small cell lung cancer. Radiat Oncol 7:33, 2012. e-Pub 2012. PMID: 22420631.
- Suzuki A, Xiao L, Hayashi Y, Macapinlac HA, Welsh J, Lin SH, Lee JH, Bhutani MS, Maru DM, Hofstetter WL, Swisher SG, Ajani JA. Prognostic significance of baseline positron emission tomography and importance of clinical complete response in patients with esophageal or gastroesophageal junction cancer treated with definitive chemoradiotherapy. Cancer 117(21):4822-4833, 2011. e-Pub 2011. PMID: 21456015.
- Hristov B, Reddy S, LinSH, Cameron JL, Pawlik TM, Hruban RH, Swartz MJ, Edil BH, Kemp C, Wolfgang CL, Herman JM. Outcomes of adjuvant chemoradiation after pancreaticoduodenectomy with mesenterico-portal vein resection for adenocarcinoma of the pancreas. Int J Radiat Oncol Biol Phys 76(1):176-180, 2010. e-Pub 2010. PMID: 19394156.
- Tan AC, Jimeno A, Lin SH, Wheelhouse J, Chan F, Solomon A, Rajeshkumar NV, Rubio-Viqueira B, Hidalgo M. Characterizing DNA methylation patterns in pancreatic cancer genome. Mol Oncol 3(5-6):425-438, 2009. e-Pub 2009. PMID: 19497796.
- Yi JM, Tsai HC, Glöckner SC, Lin SH, Ohm JE, Easwaran H, James CD, Costello JF, Riggins G, Eberhart CG, Laterra J, Vescovi AL, Ahuja N, Herman JG, Schuebel KE, Baylin SB. Abnormal DNA methylation of CD133 in Colorectal and Glioblastoma Tumors. Cancer Res 68(19):8094-8103, 2008. e-Pub 2008. PMID: 18829568.
- Lin SH, Sugar E, Teslow T, McNutt T, Saleh H, Song DY. Comparison of daily couch shifts using MVCT (TomoTherapy) and B-mode Ultrasound (BAT system) during prostate radiotherapy. Technol Cancer Res Treat 7(4):279-286, 2008. e-Pub 2008. PMID: 18642966.
- Lin SH, Latronico D, Teslow T, Bajaj GK. A highly reproducible bolus immobilization technique for the treatment of scalp malignancies. Med Dosim 33(1):30-35, 2008. e-Pub 2008. PMID: 18262120.
- Nagasaki H, Wang Z, Jackson VR, Lin SH, Nothacker HP, Civelli O. Differential expression of the thyrostimulin subunits, glycoprotein alpha2 and beta5 in the rat pituitary. J Mol Endocrinol 37(1):39-50, 2006. e-Pub 2006. PMID: 16901922.
- Jackson VR, Lin SH, Wang Z, Nothacker HP, Civelli O. A study of the rat neuropeptide B/neuropeptide W system using in situ techniques. J Comp Neurol 497(3):367-383, 2006. e-Pub 2006. PMID: 16736466.
- Xu YL, Reinscheid RK, Huitron-Resendiz S, Clark SD, Wang Z, Lin SH, Brucher FA, Zeng J, Ly NK, Henriksen SJ, de Lecea L, Civelli O. Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects. Neuron 43(4):487-497, 2004. e-Pub 2004. PMID: 15312648.
- Lin SH, Leslie FM, Civelli O. Neurochemical properties of the prolactin releasing peptide (PrRP) receptor expressing neurons: evidence for a role of PrRP as a regulator of stress and nociception. Brain Res 952(1):15-30, 2002. e-Pub 2002. PMID: 12363400.
- Lin SH, Arai AC, España RA, Berridge CW, Leslie FM, Huguenard JR, Vergnes M, Civelli O. Prolactin-releasing peptide (PrRP) promotes awakening and suppresses absence seizures. Neuroscience 114(1):229-238, 2002. e-Pub 2002. PMID: 12207968.
- Lin SH, Arai AC, Wang Z, Nothacker HP, Civelli O. The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor clustering. Mol Pharmacol 60(5):916-923, 2001. e-Pub 2001. PMID: 11641419.
- Nothacker HP, Wang Z, Zhu Y, Reinscheid RK, Lin SH, Civelli O. Molecular cloning and characterization of a second human cysteinyl leukotriene receptor: discovery of a subtype selective agonist. Mol Pharmacol 58(6):1601-1608, 2000. e-Pub 2000.
- Saito Y, Nothacker HP, Wang Z, Lin SH, Leslie F, Civelli O. Molecular characterization of the melanin-concentrating hormone receptor. Nature 400(400):265-269, 1999. e-Pub 1999. PMID: 10421368.
Invited Articles
- Xi M, Lin SH. Recent advances in intensity modulated radiotherapy and proton therapy for esophageal cancer. Expert Rev Anticancer Ther, 2017. e-Pub 2017.
- Verma V, Lin SH. Implications of the Bystander and Abscopal Effects of Radiation Therapy. Clin Cancer Res 22(19):4763-4765, 2016. e-Pub 2016. PMID: 27458248.
- van Rossum PSN, Xu C, Fried DV, Goense L, Court LE, Lin SH. The emerging field of radiomics in esophageal cancer: current evidence and future potential. Transl Cancer Res 5(4):410-423, 2016. e-Pub 2016.
- Lin SH. Invited Commentary: Prognostic significance of vascular and lymphatic emboli in resected pulmonary adenocarcinoma. Ann Thorac Surg 95(4):1210-1211, 2013. e-Pub 2013.
- Lin SH. The utility of protonbBeam therapy with concurrent chemotherapy for the treatment of esophageal cancers. Cancers (Basel) 3(4):4090-4101, 2011. e-Pub 2011. PMID: 24213126.
- Lin SH, Chang JY. Esophageal Cancer: Diagnosis and Management. Chinese Journal of Cancer 29(8):67-78, 2010. e-Pub 2010.
Review Articles
- López Moreno, SF, Lenz, SA, Casso-Chapa, B, Paniagua Bojorges, A, Kim, JH, Palaskas, NL, Nead, KT, Samanthapudi, VS, Mejia, G, Hoang, ON, Lee, J, Lin, SH, Herrmann, J, Wang, G, Yusuf, SW, Iliescu, C, Beinart, N, Manisty, C, Ushio-Fukai, M, Fukai, T, Ameri, P, Nurieva, R, Hildebrandt, MA, Schadler, KL, Koutroumpakis, E, Kotla, S, Le, NT, Abe, J. SHP2. Antioxidants 14(12), 2025. e-Pub 2025. PMID: 41462587.
- Abe, J, Chau, KM, Mojiri, A, Wang, G, Oikawa, M, Samanthapudi, VS, Osborn, AM, Ostos-Mendoza, KC, Mariscal-Reyes, KN, Mathur, T, Jain, A, Herrmann, J, Yusuf, SW, Krishnan, S, Deswal, A, Lin, SH, Kotla, S, Cooke, J, Le, NT. Impacts of Radiation on Metabolism and Vascular Cell Senescence. Antioxidants and Redox Signaling 43(1-3):92-114, 2025. e-Pub 2025. PMID: 40233257.
- Ozair, MZ, Halmos, B, D'Aiello, A, Yun, J, Filippi, AR, Rimner, A, Lin, SH, Simone, C, Ohri, N. Chemotherapy-Free Treatment with Radiotherapy and Immunotherapy for Locally Advanced Non-Small Cell Lung Cancer. Cancers 17(9), 2025. e-Pub 2025. PMID: 40361451.
- Casso-Chapa, B, Vazquez González, NA, Le, NT, Palaskas, NL, Nead, KT, Eutsey, LP, Samanthapudi, VS, Osborn, AM, Lee, J, Mejia, G, Hoang, ON, Lin, SH, Deswal, A, Herrmann, J, Wang, G, Kirkland, J, Krishnan, S, Wehrens, XH, Chini, EN, Yusuf, SW, Iliescu, C, Jain, A, Burks, JK, Seeley, EH, Lorenzi, PL, Chau, KM, Ostos-Mendoza, KC, Grumbach, IM, Brookes, PS, Hanssen, NM, de Winther, M, Yvan-Charvet, L, Kotla, S, Schadler, KL, Abe, J. Reevaluating Anti-Inflammatory Therapy. Arteriosclerosis, thrombosis, and vascular biology 45(3):372-385, 2025. e-Pub 2025. PMID: 39817327.
- Zumsteg, ZS, Sheth, S, Jabbour, SK, Patel, KR, Kimple, RJ, Williams, TM, Welliver, MX, Torres-Saavedra, P, Monjazeb, AM, Mayadev, J, Finkelstein, SE, Buatti, JM, Patel, SP, Lin, SH. Challenges and opportunities for early phase clinical trials of novel drug–radiotherapy combinations. The lancet oncology 25(10):e489-e500, 2024. e-Pub 2024. PMID: 39362260.
- Banerjee, P, Rosales, JE, Chau, KM, Nguyen, MT, Kotla, S, Lin, SH, Deswal, A, Dantzer, R, Olmsted-Davis, EA, Nguyen, H, Wang, G, Cooke, J, Abe, J, Le, NT. Possible molecular mechanisms underlying the development of atherosclerosis in cancer survivors. Frontiers in Cardiovascular Medicine 10, 2023. e-Pub 2023. PMID: 37332576.
- Nelson BE, Adashek JJ, Lin SH, Subbiah V. The abscopal effect in patients with cancer receiving immunotherapy. Med 4(4):233-244, 2023. e-Pub 2023. PMID: 36893753.
- Joo L, Bradley CC, Lin SH, Scheet PA, Nead KT. Causes of Clonal Hematopoiesis: a Review. Curr Oncol Rep 25(3):211-220, 2023. e-Pub 2023. PMID: 36719597.
- Nelson BE, Adashek JJ, Lin SH, Subbiah V. On target methods to induce abscopal phenomenon for Off-Target effects: From happenstance to happenings. Cancer Med 12(6):6451-6465, 2023. e-Pub 2023. PMID: 36411943.
- Jain, A, Casanova, D, Padilla, AV, Paniagua Bojorges, A, Kotla, S, Ko, KA, Samanthapudi, VS, Chau, KM, Nguyen, MT, Wen, J, Hernandez Gonzalez, SL, Rodgers, SP, Olmsted-Davis, EA, Hamilton, DJ, Reyes-Gibby, CC, Yeung, SJ, Cooke, J, Herrmann, J, Chini, EN, Xu, X, Yusuf, SW, Yoshimoto, M, Lorenzi, PL, Hobbs, BP, Krishnan, S, Koutroumpakis, E, Palaskas, NL, Wang, G, Deswal, A, Lin, SH, Abe, J, Le, NT. Premature senescence and cardiovascular disease following cancer treatments. Frontiers in Cardiovascular Medicine 10, 2023. e-Pub 2023. PMID: 37781317.
- Verma V, Yegya-Raman N, Sprave T, Han G, Kantarjian HM, Welsh JW, Chang JY, Lin SH. A Systematic Review of the Cost-Effectiveness of Stereotactic Radiation Therapy for Cancer Oligometastases. Int J Radiat Oncol Biol Phys 114(5):977-988, 2022. e-Pub 2022. PMID: 35675852.
- Verma, V, Lin, SH. Proton beam radiotherapy for esophageal cancer. Precision Radiation Oncology 6(3):257-261, 2022. e-Pub 2022.
- Banerjee, P, Olmsted-Davis, EA, Deswal, A, Nguyen, MT, Koutroumpakis, E, Palaskas, NL, Lin, SH, Kotla, S, Reyes-Gibby, CC, Yeung, SJ, Yusuf, SW, Yoshimoto, M, Kobayashi, M, Yu, B, Schadler, KL, Herrmann, J, Cooke, J, Jain, A, Chini, EN, Le, NT, Abe, J. Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications. Journal of Cardiovascular Aging 2(3), 2022. e-Pub 2022. PMID: 35801078.
- Koutroumpakis, E, Deswal, A, Yusuf, SW, Abe, J, Nead, KT, Potter, A, Liao, Z, Lin, SH, Palaskas, NL. Radiation-Induced Cardiovascular Disease. Current oncology reports 24(5):543-553, 2022. e-Pub 2022. PMID: 35192118.
- Tomassen, ML, Pomp, J, van der Stap, J, van Lindert, AS, Peters, M, Belderbos, JS, De Ruysscher, DK, Lin, SH, Verhoeff, JJ, van Rossum, P. The overall survival impact of prophylactic cranial irradiation in limited-stage small-cell lung cancer. Clinical and Translational Radiation Oncology 33:145-152, 2022. e-Pub 2022. PMID: 35243025.
- Damen PJJ, Kroese TE, van Hillegersberg R, Schuit E, Peters M, Verhoeff JJC, Lin SH, van Rossum PSN. The influence of severe radiation-induced lymphopenia on overall survival in solid tumors: a systematic review and meta-analysis. Int J Radiat Oncol Biol Phys, 2021. e-Pub 2021. PMID: 34329738.
- Koutroumpakis E, Palaskas NL, Lin SH, Abe JI, Liao Z, Banchs J, Deswal A, Yusuf SW. Modern Radiotherapy and Risk of Cardiotoxicity. Chemotherapy:1-12, 2020. e-Pub 2020. PMID: 33049738.
- Moreno AC, Lin SH. The optimal treatment approaches for stage I small cell lung cancer. Transl Lung Cancer Res 8(1):88-96, 2019. e-Pub 2019. PMID: 30788238.
- Badiyan SN, Hallemeier CL, Lin SH, Hall MD, Chuong MD. Proton beam therapy for gastrointestinal cancers: past, present, and future. J Gastrointest Oncol 9(5):962-971, 2018. e-Pub 2018. PMID: 30505599.
- Liao Z, Gandhi SJ, Lin SH, Bradley J. Does Proton Therapy Offer Demonstrable Clinical Advantages for Treating Thoracic Tumors?. Semin Radiat Oncol 28(2):114-124, 2018. e-Pub 2018. PMID: 29735187.
- Venkatesulu BP, Mallick S, Lin SH, Krishnan S. A systematic review of the influence of radiation-induced lymphopenia on survival outcomes in solid tumors. Crit Rev Oncol Hematol 123:42-51, 2018. e-Pub 2018. PMID: 29482778.
- Deng W, Lin SH. Advances in radiotherapy for esophageal cancer. Ann Transl Med 6(4):79, 2018. e-Pub 2018. PMID: 29666802.
- Wang Y, Deng W, Li N, Neri S, Sharma A, Jiang W, Lin SH. Combining Immunotherapy and Radiotherapy for Cancer Treatment: Current Challenges and Future Directions. Front Pharmacol 9:185, 2018. e-Pub 2018. PMID: 29556198.
- Jamorabo DS, Lin SH, Jabbour SK. Successes and Failures of Combined Modalities in Upper Gastrointestinal Malignancies: New Directions. Semin Radiat Oncol 26(4):307-19, 2016. e-Pub 2016. PMID: 27619252.
- Chuong MD, Hallemeier CL, Jabbour SK, Yu J, Badiyan S, Merrell KW, Mishra MV, Li H, Verma V, Lin SH. Improving Outcomes for Esophageal Cancer using Proton Beam Therapy. Int J Radiat Oncol Biol Phys 95(1):488-497, 2016. e-Pub 2016. PMID: 27084662.
- Chung H, Court L, Lin SH, Kulkarni D, Balter P. Evaluation of dose variation to normal and critical structures for lung hypofractionated stereotactic body radiation therapy. Pract Radiat Oncol 2(3):e15-e21, 2012. e-Pub 2012. PMID: 24674129.
- Liao Z, Lin SH, Cox JD. Status of Particle therapy for lung cancer. Acta Oncol 50(6):745-756, 2011. e-Pub 2011. PMID: 21767170.
- Lin SH, Kleinberg LR. Carmustine Wafers: Localized delivery of chemotherapeutic agents in CNS malignancies. Expert Rev Anticancer Ther 8(3):343-359, 2008. e-Pub 2008. PMID: 18366283.
- Lin SH. Prolactin Releasing Peptide. Results Probl Cell Differ 46:57-88, 2008. e-Pub 2008. PMID: 18204826.
- Lin SH, Civelli O. Orphan G protein-coupled receptors: targets for new therapeutic interventions. Ann Med 36(3):204-214, 2004. e-Pub 2004. PMID: 15181976.
- Civelli O, Nothacker HP, Saito Y, Wang Z, Lin SH, Reinscheid RK. Novel neurotransmitters as natural ligands of orphan G protein-coupled receptors. Trends Neurosci 24(4):230-237, 2001. e-Pub 2001. PMID: 11250008.
Other Articles
- Ohannesian, N, Mallick, MS, He, J, Qiao, Y, Li, N, Shaitelman, SF, Tang, C, Shinn, EH, Hofstetter, WL, Goltsov, A, Hassan, MM, Hunt, KK, Lin, SH, Shih, WC Correction to. Communications Medicine 4(1), 2024. PMID: 38942807.
Editorials
- Damen, PJ, Lin, SH, van Rossum, P. Editorial. Frontiers in Oncology 14, 2024. PMID: 39015501.
- Xu C, Lin SH. Deciding on the neoadjuvant approach for esophageal adenocarcinomas. J Thorac Dis 9(7):1818–1821, 2017.
Abstracts
- Zhou N, Hofstetter WL, Working Group ESCC, Mitchell KG, Bayley EM, Ajani JA, Antonoff MB, Betancourt SL, Blum-Murphy M, Feldman HA, Lin SH, Maru DM, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Weston BR. Salvage Esophagectomy Definition Influences Comparative Outcomes in Esophageal Squamous Cell Cancers. The Annals of Thoracic Surgery, 2021. e-Pub 2021.
Book Chapters
- Lin, SH, Raben, D. Optimizing Drug Therapies in the Maintenance Setting After Radiochemotherapy in Non-small Cell Lung Cancer, 571-580, 2023.
- Ning, M, Verma, V, Lin, SH. Thoracic Malignancies, 261-285, 2022.
- Lin SH, Komaki R. Molecular Targeted Treatment for Personalized Radiotherapy in Lung Cancer. In: Lung Cancer. 4th Edition. John Wiley & Sons, Inc, 2014.
- Lin SH. Adjuvant Therapy for NSCLC Following Surgical Resection. In: Personalized Management of Lung Cancer. Future Science Group (FSG), 2013.
- Lin SH, Lee VJ. Ear Cancer. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 538-539, 2010.
- Lin SH, Roland E. Melanoma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 521-528, 2010.
- Lin SH, Rengan R. Hemangiopericytoma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 510-511, 2010.
- Lin SH, Alonso-Basanta M. Chordoma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 498-501, 2010.
- Lin SH, Plastaras JP. MALT Lymphoma (Gastric and Ocular Adnexa and Other Sites). In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 472-477, 2010.
- Lin SH, Glatstein E. Hodgkin Disease. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 457-464, 2010.
- Lin SH, Liao Z. Esophageal Cancer. In: Radiation Oncology A Question Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 285-296, 2010.
- Lin SH, Zellars RC. Early-Stage (I-II) Breast Cancer. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 260-272, 2010.
- Lin SH, Bucci KM. Pleural Mesothelioma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 238-246, 2010.
- Lin SH, Jeter MD. Thymoma and Thymic Carcinoma. In: Radiation Oncology a Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 232-238, 2010.
- Lin SH, Welsh J. Advanced-Stage (III-IV) Non-Small Cell Lung Cancer. In: Radation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 209-222, 2010.
- Lin SH, Lee VJ. Neck Management and Postoperative Radiation Therapy for Head and Neck Cancers. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 195-198, 2010.
- Lin SH, Bajaj GK. Laryngeal and Hypopharyngeal Cancers. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 172-182, 2010.
- Lin SH, Sanguineti G. Oropharyngeal Cancer. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 157-165, 2010.
- Lin SH, Bajaj GK. Oral Cavity Cancer. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 149-157, 2010.
- Lin SH, Lee VJ. Ocular Melanoma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 123-129, 2010.
- Lin SH, Chan TA. Primary Central Nervous System Lymphoma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/lippincott Williams & Wilkins, 91-98, 2010.
- Lin SH, Woo SY. High -Grade Glioma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 82-88, 2010.
- Lin SH, Mahajan A. General Central Nervous System. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 73-76, 2010.
- Lin SH, Ori S. Hemangioblastoma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 67-69, 2010.
- Hristov B, Lin SH, Christodouleas JP. Ependymoma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 54-58, 2010.
- Hristov B, Lin SH, Christodouleas JP. Rhabdomyosarcoma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 1-12, 2010.
- Lin SH, Ori S. Brainstem Glioma. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 70-72, 2010.
- Lin SH, Jabbour S. Gastric Cancer. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 296-304, 2010.
- Lin SH, Chang JY. Lung Cancer. In: Decision Making in Radiation Oncology. 2nd Edition. Springer-Verlag, 261-307, 2010.
- Lin SH, Liao Z. Esophageal Cancer. In: Decision Making in Radiation Oncology. 2nd Edition. Springer-Verlag, 329-358, 2010.
- Lin SH, Wharam, Jr MD. Wilms Tumor. In: Radiation Oncology A Question-Based Review. Wolters Kluwer/Lippincott Williams & Wilkins, 20-30, 2010.
Books (edited and written)
- Hristov B, Lin SH, Christodouleas JP. Radiation Oncology: A Question-based Review. Ed(s) 2nd edition. Wolters Kluwer, Lippincott, Williams & Wilkins, 2014.
- Hristov B, Lin SH, Christodouleas JP. Radiation Oncology: A Question-based Review. Ed(s) 1st Edition. Wolters Kluwer, Lippincott, Williams & Wilkins, 2011.
Patents
- Methods of identifying compounds for controlling absence seizures in a mammal relating to prolactin-releasing peptide(PrRP). Patent Number: 6,383,764.
- Screening and therapeutic methods for promoting wakefulness and sleep. Patent Number: 6,884,596.
Patient Reviews
CV information above last modified March 25, 2026