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Subrata Sen, Ph.D.

Present Title & Affiliation

Primary Appointment

Professor & Deputy Chair, Department of Translational Molecular Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Adjunct Professor, The University of Texas Health Science Center at Houston, School of Public Health, Houston, TX
Faculty Member, The University of Texas Graduate School of Biomedical Sciences, Houston, TX

Office Address

The University of Texas MD Anderson Cancer Center
Department of Molecular Pathology
7435 Fannin Street
Unit Number: 951
Houston, TX 77054
Room Number: 2SCR4.3027
Phone: (713) 834-6040
Fax: (713) 834-6087
Email: ssen@mdanderson.org

Education & Training

Degree-Granting Education

1988 The University of Texas MD Anderson Cancer Center, Houston, TX, Post Doctoral Fellow, Chromatin Structure
1980 Center of Advanced Studies in Zoology, College of Science, Banaras Hindu University, Varanasi, India, PHD, Molecular Cytogenetics, Zoology
1974 Center of Advanced Studies in Zoology, College of Science, Banaras Hindu University, Varanasi, India, MS, Zoology, Cytogenetics as the Elective Subject
1972 College of Science, Banaras Hindu University With Honors, Varanasi, India, BS, Botany, Zoology, Chemistry

Postgraduate Training

1991 Visiting Fellow, University of Illinois College of Medicine (Department of Genetics), Chicago, IL, Dr. Ignor Roninson

Experience/Service

Academic Appointments

Faculty Member, The University of Texas Medical School, Houston, TX, 2004-present
Associate Professor, Department of Molecular Pathology, Division of Pathology & Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 1999-2010
Assistant Professor, Division of Pathology and Laboratory Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 1997-1999
Associate Biologist, Department of Molecular Pathology, Division of Pathology & Laboratory Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 1997-1998
Assistant Professor, Division of Laboratory Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 1990-1997
Assistant Biologist, Division of Laboratory Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX, 1987-1990
Lecturer, Department of Zoology, Banaras Hindu University, Varanasi, India, 1980-1982

Selected Publications

Peer-Reviewed Original Research Articles

1. Yang G, Mercado-Uribe I, Multani S, Sen S, Shih IM, Wong KK, Gershenson DM, Lui J. Ras promotes tumorgenesis through genomic instability induced by imbalanced expression of Aurora-A and BRCA2. International J. Cancer. In Press.
2. Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR. Aurora Kinase-A Dificiency During Skin Development Impairs Cell Division and Stratification. J. Invest Dermatol. 133:78-86, 7/2012. PMCID: PMC22832491.
3. Liu Q, Chen J, Mai B, Amos C, Killary AM, Sen S, Wei C, Frazier ML. A single-nucleotide polymorphism in tumor suppressor gene SEL1L as a predictive and prognostic marker for pancreatic ductal adenocarcinoma in caucasians. Mol Carcinog 51(5):433-8, 5/2012. e-Pub 6/2011. PMCID: PMC21656579.
4. Katayama H, Wang J, Treekitkarnmongkol W, Kawai H, Sasai K, Zhang H, Wang H, Adams HP, Jiang S, Chakraborty SN, Suzuki F, Arlinghaus RB, Liu J, Mobley JA, Grizzle WE, Wang H, Sen S. Aurora kinase-A inactivates DNA damage-induced apoptosis and spindle assembly checkpoint response functions of p73. Cancer Cell 21(2):196-211, 2/2012. PMID: 22340593.
5. Derenzini E, Lemoine M, Buglio D, Katayama H, Ji Y, Davis RE, Sen S, Younes A. The JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma. Blood Cancer J. 12(46), 12/2011. PMCID: PMC22829094.
6. Wang J, Sen S. MicroRNA functional network in pancreatic cancer: From biology to biomarkers of disease. J Biosci 36(3):481-491, 8/2011. PMCID: PMC21799259.
7. Chen J, Wu X, Pande M, Amos CI, Killary AM, Sen S, Frazier ML. Susceptibility locus for lung cancer at 15q25.1 is not associated with risk of pancreatic cancer. Pancreas 40(6):872-875, 8/2011. PMCID: PMC3138891.
8. Katayama H, Sen S. Functional Significance of Aurora Kinase A Regulatory Interactions with p53-ERα Complex in Human Breast Cancer Cells. Horm Cancer 2(2):117-124, 4/2011. PMCID: PMC21761334.
9. Balasenthil S, Chen N, Lott ST, Chen J, Carter J, Grizzle WE, Frazier ML, Sen S, Killary AM. A migration signature and plasma biomarker panel for pancreatic adenocarcinoma. Cancer Prev Res (Phila) 4(1):137-49, 1/2011. e-Pub 11/2010. PMCID: PMC21071578.
10. Katayama H, Sen S. Aurora kinase inhibitors as anticancer molecules. Biochim Biophys Acta 1799(10-12):829-839, 9/2010. PMCID: PMC20863917.
11. Molli PR, Li DQ, Bagheri-Yarmand R, Pakala SB, Katayama H, Sen S, Iyer J, Chernoff J, Tsai MY, Nair SS, Kumar R. Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A. J Cell Biol 190(1):101-114, 7/12/2010. e-Pub 7/5/2010. PMCID: PMC2911675.
12. Yang G, Chang B, Yang F, Guo X, Cai KQ, Xiao XS, Wang H, Sen S, Hung MC, Mills GB, Chang S, Multani AS, Mercado-Uribe I, Liu J. Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2. Clin Cancer Res 16(12):3171-3181, 6/15/2010. e-Pub 4/27/2010. PMCID: PMC2930838.
13. Frenkel M, Mishra BM, Sen S, Yang P, Pawlus A, Vence L, Leblanc A, Cohen L, Banerji P, Banerji P. Cytotoxic effects of ultra-diluted remedies on breast cancer cells. Int J Oncol 36(2):395-403, 2/2010. PMCID: PMC20043074.
14. Jiang S, Katayama H, Wang J, Li SA, Hong Y, Radvanyi L, Li JJ, Sen S. Estrogen-Induced Aurora Kinase-A (AURKA) Gene Expression is Activated by GATA-3 in Estrogen Receptor-Positive Breast Cancer Cells. Horm Cancer 1(1):11-20, 2/2010. e-Pub 2/2010. PMCID: PMC21761347.
15. Zhu J, Sen S, Wei C, Frazier ML. Cyclin D1b represses breast cancer cell growth by antagonizing the action of cyclin D1a on estrogen receptor alpha-mediated transcription. Int J Oncol 36(1):39-48, 1/2010. PMCID: PMC19956831.
16. Chen J, Amos CI, Merriman KW, Wei Q, Sen S, Killary AM, Frazier ML. Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic Whites: a case-control study. Pancreas 39(1):1-4, 1/2010. PMCID: PMC2796289.
17. Sen S. Aurora-C: the youngest of "the three (Aurora kinase) tenors" of mitotic symphony. Cell Cycle 8(19):3076-7, 10/2009. PMCID: PMC19823009.
18. Torchia EC, Chen Y, Sheng H, Katayama H, Fitzpatrick J, Brinkley WR, Caulin C, Sen S, Roop DR. A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors. Cancer Res 69(18):7207-7215, 9/15/2009. e-Pub 9/8/2009. PMCID: PMC2745523.
19. Wang J, Chen J, Chang P, LeBlanc A, Li D, Abbruzzesse JL, Frazier ML, Killary AM, Sen S. MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease. Cancer Prev Res (Phila) 2(9):807-813, 9/2009. e-Pub 9/2009. PMCID: PMC19723895.
20. Lott ST, Chen N, Chandler DS, Yang Q, Wang L, Rodriguez M, Xie H, Balasenthil S, Buchholz TA, Sahin AA, Chaung K, Zhang B, Olufemi SE, Chen J, Adams H, Band V, El-Naggar AK, Frazier ML, Keyomarsi K, Hunt KK, Sen S, Haffty B, Hewitt SM, Krahe R, Killary AM. DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence free survival in early onset breast cancer. PLoS Med 6(5):e1000068, 5/26/2009. e-Pub 5/5/2009. PMCID: PMC2673042.
21. Mazumdar A, Henderson YC, El-Naggar AK, Sen S, Clayman GL. Aurora Kinase A Inhibition and Paclitaxel as Targeted Combination Therapy for Head and Neck Squamous Cell Carcinoma. Head Neck 31(5):625-34, 5/2009. e-Pub 12/2008. PMCID: PMC2668723.
22. Chen J, Li D, Killary AM, Sen S, Amos CI, Evans DB, Abbruzzese JL, Frazier ML. Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation. Ann Surg Oncol 16(2):431-9, 2/2009. e-Pub 11/2008. PMCID: PMC19020940.
23. Inamdar KV, O'Brien S, Sen S, Keating M, Nguyen MH, Wang X, Fernandez M, Thomazy V, Medeiros LJ, Bueso-Ramos CE. Aurora-A kinase nuclear expression in chronic lymphocytic leukemia. Mod Pathol 12(12):1428-1435, 12/2008. e-Pub 10/2008. PMCID: PMC18931650.
24. Chen J, Killary AM, Sen S, Amos CI, Evans DB, Abbruzzese JL, Frazier ML. Polymorphisms of p21 and p27 jointly contribute to an earlier age at diagnosis of pancreatic cancer. Cancer Lett 272(1):32-9, 12/2008. e-Pub 8/2008. PMCID: PMC18694622.
25. Park HS, Park WS, Bondaruk J, Tanaka N, Katayama H, Lee S, Spiess PE, Steinberg JR, Wang Z, Katz RL, Dinney C, Elias KJ, Lotan Y, Naeem RC, Baggerly K, Sen S, Grossman HB, Czerniak B. Quantitation of Aurora Kinase a gene copy number in urine sediments and bladder cancer detection. J Natl Cancer Inst 100(19):1401-1411, 10/1/2008. e-Pub 9/23/2008. PMCID: PMC2720731.
26. Katayama H, Sasai K, Kloc M, Brinkley BR, Sen S. Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells. Cell Cycle 7(17):2691-704, 9/2008. PMCID: PMC18773538.
27. Sasai K, Parant JM, Brandt ME, Carter J, Adams HP, Stass SA, Killary AM, Katayama H, Sen S. Targeted disruption of Aurora-A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality. Oncogene 27(29):4122-4127, 7/2008. e-Pub 3/2008. PMCID: PMC18345035.
28. Sen S, Katayama H, Sasai K. Functional significance of Aurora Kinase A in Centrosome amplification and genomic instability. Adv Exp Med Biol 617:99-108, 2008. PMCID: PMC18497034.
29. Katayama H, Sasai K, Czerniak BA, Carter JL, Sen S. Aurora-A kinase phosphorylation of Aurora-A kinase interacting protein (AIP) and stabilization of the enzyme-substrate complex. J Cell Biochem 102(5):1318-1331, 12/2007. PMCID: PMC17957726.
30. Chen J, Li D, Wei C, Sen S, Killary AM, Amos CI, Evans DB, Abbruzzese JL, Frazier ML. Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians. Clin Cancer Res 13(10):3100-3104, 5/15/2007. PMCID: PMC2365501.
31. Chen J, Sen S, Amos CI, Wei C, Jones JS, Lynch P, Frazier ML. Association between Aurora-A kinase polymorphisms and age of onset of hereditary nonpolyposis colorectal cancer in a Caucasian population. Mol Carcinog 46(4):249-56, 4/2007. PMCID: PMC17219423.
32. Shi Y, Reiman T, Li W, Maxwell CA, Sen S, Pilarski L, Daniels TR, Penichet ML, Feldman R, Lichtenstein A. Targeting aurora kinases as therapy in multiple myeloma. Blood 109:3915-3921, 1/2007.
33. Hu Q, Lu JF, Luo R, Sen S, Maity SN. Inhibition of CBF/NF-Y mediated transcription activation arrests cells at G2/M phase and suppresses expression of genes activated at G2/M phase of the cell cycle. Nucleic Acids Res 34:6272-85, 2007. PMCID: PMC17098936.
34. Carter JL, Jin Li, Sen S. Genomic and expression array profiling of chromosome 20q amplicon in human colon cancer cells. Human Genetics 11:128-134, 1/2005.
35. Hu W, Kavanagh JJ, Deaver M, Johnston DA, Freedman RS, Verschraegen CF, Sen S. Frequent overexpression of STK15/Aurora-A/BTAK and chromosomal instability in tumorigenic cell cultures derived from human ovarian cancer. Oncol Res 15(1):49-57, 2005. PMCID: PMC15839305.
36. Fraizer GC, Diaz MF, Lee IL, Grossman HB, Sen S. Aurora-A/STK15/BTAK enhances chromosomal instability in bladder cancer cells. Int J Oncol 25(6):1631-9, 12/2004. PMCID: PMC15547700.
37. Sasai K, Katayama H, Stenoien DL, Fujii S, Honda R, Kimura M, Okano Y, Tatsuka M, Suzuki F, Nigg EA, Earnshaw WC, Brinkley WR, Sen S. Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motil Cytoskeleton 59(4):249-63, 12/2004. NIHMSID: NIHMS15499654.
38. Ouchi M, Fujiuchi N, Sasai K, Katayama H, Minamishima YA, Ongusaha PP, Deng C, Sen S, Lee SW, Ouchi T. BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition. J Biol Chem 279(19):19643-8, 5/2004. e-Pub 2/2004. PMCID: PMC14990569.
39. Katayama H, Sasai K, Kawai H, Yuan ZM, Bondaruk J, Suzuki F, Fujii S, Arlinghaus RB, Czerniak BA, Sen S. Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53. Nat Genet 36(1):55-62, 1/2004. e-Pub 12/2003. PMCID: PMC14702041.
40. Royce ME, Xia W, Sahin AA, Katayama H, Johnston DA, Hortobagyi G, Sen S, Hung MC. STK15/Aurora-A expression in primary breast tumors is correlated with nuclear grade but not with prognosis. Cancer 100(1):12-9, 1/2004. PMCID: PMC14692019.
41. Katayama H, Brinkley WR, Sen S. Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells. Cancer Metastasis Rev 22(3):451-464, 12/2003. PMCID: PMC18773538.
42. Hoque A, Carter J, Xia W, Hung MC, Sahin AA, Sen S, Lippman SM. Loss of aurora A/STK15/BTAK overexpression correlates with transition of in situ to invasive ductal carcinoma of the breast. Cancer Epidemiol Biomarkers Prev 12(12):1518-22, 12/2003. PMID: 14693746.
43. Mayer F, Stoop H, Sen S, Bokemeyer C, Oosterhuis JW, Looijenga LH. Aneuploidy of human testicular germ cell tumors is associated with amplification of centrosomes. Oncogene 22:3859-66, 6/2003. PMCID: PMC12813459.
44. Stenoien DL, Sen S, Mancini MA, Brinkley BR. Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. Cell Motil Cytoskeleton 55:134-46, 6/2003. PMCID: PMC12740874.
45. Li D, Zhu J, Firozi PF, Abbruzzese JL, Evans DB, Cleary K, Friess H, Sen S. Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer. Clin Cancer Res 9:991-7, 3/2003. PMCID: PMC12631597.
46. Sen S, Zhou H, Zhang RD, Yoon DS, Vakar-Lopez F, Ito S, Jiang F, Johnston D, Grossman HB, Ruifrok AC, Katz RL, Brinkley W, Czerniak B. Amplification/overexpression of a mitotic kinase gene in human bladder cancer. J Natl Cancer Inst 94:1320-9, 9/2002. PMCID: PMC12208897.
47. Li F, Adam L, Vadlamudi RK, Zhou H, Sen S, Chernoff J, Mandal M, Kumar R. p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells. EMBO Rep 3:767-73, 8/2002. PMCID: PMC12151336.
48. Crosio C, Fimia GM, Loury R, Kimura M, Okano Y, Zhou H, Sen S, Allis CD, Sassone-Corsi P. Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases. Mol Cell Biol 22:874-85, 2/2002. PMCID: PMC11784863.
49. Katayama H, Zhou H, Li Q, Tatsuka M, Sen S. Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle. J Biol Chem 276(49):46219-24, 12/2001. e-Pub 9/2001. PMCID: PMC11551964.
50. Multani AS, Ozen M, Sen S, Mandal AK, Price JE, Fan D, Radinsky R, Ali-Osman F, Von Eschenbach AC, Fidler IJ, Pathak S. Amplification of telomeric DNA directly correlates with metastatic potential of human and murine cancers of various histological origin. Int J Oncol 15:423-9, 9/1999. PMCID: PMC10427120.
51. Multani AS, Chandra J, McConker J, Sen S, Cabral TF, Pathak S. Cell death in paclitaxel-dependent chinese hamster ovary cells is initiated by the loss of telomeric DNA repeats. Oncol Res 11:455-60, 1999. PMCID: PMC10850886.
52. Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A, Brinkley BR, Sen S. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet 20(2):189-93, 10/1998. PMCID: PMC9771714.
53. Kuo MT, Sen S, Hittelman WN, Hsu TC. Chromosomal fragile sites and DNA amplification in drug-resistant cells. Biochem Pharmacol 56:7-13, 7/1998. PMCID: PMC9698083.
54. Venugopalan M, Wood TF, Wilczynski SP, Sen S, Peters J, Ma GC, Evans GA, Srivatsan ES. Loss of heterozygosity in squamous cell carcinomas of the head and neck defines a tumor suppressor gene region on 11q13. Cancer Genet Cytogenet 104:124-32, 7/1998. PMCID: PMC9666806.
55. Sen S, Zhou H, Ripmaster T, Hittelman WN, Schimmel P, White RA. Expression of a gene encoding a tRNA synthetase-like protein is enhanced in tumorigenic human myeloid leukemia cells and is cell cycle stage- and differentiation-dependent. Proc Natl Acad Sci U S A 94:6164-9, 6/1997. PMCID: PMC9177188.
56. Sen S, Zhou H, White RA. A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines. Oncogene 14:2195-200, 5/1997. PMCID: PMC9174055.
57. Sen S, Zhou H, Andersson BS, Cork A, Freireich EJ, Stass SA. p53 gene mutations with chromosome 17 abnormalities in chronic myelogenous leukemia blast crisis patients persist in long-term cell lines but may be acquired in acute myeloid leukemia cells in vitro. Cancer Genet Cytogenet 82:35-40, 7/1995. PMCID: PMC7627932.
58. Cervantes, Zhou H, Sahin A, Dhingra K, Valero V, Ordonez N, El-Naggar A, Hess R, Glassman Aand Sen, S. P53 alterations show significant correlation with gene amplification and high S phase index in breast cancer. Int J Oncol 6:955-962, 1995. PMCID: PMC21556624.
59. Jesudasan RA, Slovak ML, Sen S, Srivatsan ES. Rearrangement of chromosome band 11q13 in HeLa cells. Anticancer Res 14:1727-33, 9/1994. PMCID: PMC7847806.
60. Sen S, Sen P, Mulac-Jericevic B, Zhou H, Pirrotta V, Stass SA. Microdissected double-minute DNA detects variable patterns of chromosomal localizations and multiple abundantly expressed transcripts in normal and leukemic cells. Genomics 19:542-51, 2/1994. PMCID: PMC8188297.
61. Sen S, Takahashi R, Rani S, Freireich EJ, Stass SA. Expression of differentially phosphorylated Rb and mutant p53 proteins in myeloid leukemia cell lines. Leuk Res 17:639-47, 8/1993. PMCID: PMC8355507.
62. Andersson BS, Bergerheim US, Collins VP, Childs C, Beran M, Sen S, Arden K, Pathak S, Siciliano MJ, Ost A, et al. KBM-3, an in vitro model of human acute myelomonocytic leukemia. Exp Hematol 20:361-7, 3/1992. PMCID: PMC1568450.
63. Sen S, Rani S, Freireich EJ, Hewitt R, Stass SA. Detection of extrachromosomal circular DNA sequences from tumor cells by an alkaline lysis, Alu-polymerase chain reaction technique. Mol Carcinog 5:107-10, 1992. PMCID: PMC1554408.
64. Sen S, Hittelman WN, Teeter LD, Kuo MT. Model for the formation of double minutes from prematurely condensed chromosomes of replicating micronuclei in drug-treated Chinese hamster ovary cells undergoing DNA amplification. Cancer Res 49:6731-7, 12/1989. PMCID: PMC2819718.
65. Sun YL, Pao CI, Sen S, Kuo T. High-resolution mapping of DNase I hypersensitive site in the chicken beta-tubulin gene transfected into monkey cells. J Biol Chem 262:7764-9, 6/1987. PMCID: PMC3584140.
66. Sen S, Teeter LD, Kuo MT. Specific gene amplification associated with consistent chromosomal abnormality in independently established multidrug-resistant Chinese hamster ovary cells. Chromosoma 95:117-25, 1987. PMCID: PMC3595311.
67. Teeter LD, Sanford JA, Sen S, Stallings RL, Siciliano MJ, Kuo MT. Multidrug-resistant phenotype cosegregates with an amplified gene in somatic cell hybrids of drug-resistant Chinese hamster ovary cells and drug-sensitive murine cells. Mol Cell Biol 6:4268-73, 12/1986. PMCID: PMC3796603.
68. Teeter LD, Atsumi S, Sen S, Kuo MT. DNA amplification in multidrug, cross-resistant Chinese hamster ovary cells: molecular characterization and cytogenetic localization of the amplified DNA. J Cell Biol 103:1159-66, 10/1986. PMCID: PMC3771630.
69. Sen S, Siciliano MJ, Johnston DA, Schwartz RJ, Kuo T. The expression and chromatin structure of the chicken glyceraldehyde-3-phosphate dehydrogenase gene in mouse cells. J Biol Chem 260:3071-8, 3/1985. PMCID: PMC3972817.
70. Kuo MT, Sen S, Teeter L, Cailleau RM, Knesek JE, Bowen J. Expression of endogenous murine leukemia virus in transplantable tumor cells and DNA methylation of the viral sequences. Cancer Res 44:3518-21, 8/1984. PMCID: PMC6331650.
71. Sen, Sharma T. Role of constitutive heterochromatin in evolutionary divergence. Results of banding and condensation inhibition studies in Mus musculus, Mus booduga and Mus dunni. Evolution 37:628-635, 1983. PMCID: PMC6331650.
72. Sen S, Sharma T. Asynchronous replication of constitutive heterochromatin on the two X chromosomes of female Mus dunni. Chromosoma (Berl) 1:119-126, 1982.
73. Sen S, Sharma T. Qualitative variation of Mus musculus like constitutive heterochromatin and sate11ite DNA sequences in the Genus Mus. Chromosoma (Berl) 3:393-402, 1980.
74. Sen S, Sharma T. Sparse distribution of constitutive heterochromatin and its variation in two species of mongooses (Carnivora) with exact G-band homology. Genetica 3:221-226, 1979.
75. Sen S, Gupta JPGupta. Some studies on the systematic position of D. andamanensis Gupta and Ray-Chaudhuri. Drosophila Information Service 52:33-34, 1977.

Invited Articles

1. Katayama H, Sen S. Aurora Kinase inhibitors as Anticancer Molecules. Biochim Biophys Acta 1799(10-12):829-39, Oct-Dec, 10/2010. e-Pub 9/20/2010. PMID: 20863917.
2. Sen S. Aurora-C Joins "The Three (Aurora Kinase) Tenors of Mitotic Symphony". Cell Cycle (News & Views), 2009.
3. Sen S. Aneuploidy. Encyclopedia of Cancer, 2nd Edition, Springer Verlag, Berlin Heidelberg:158-164, 2008.
4. Katayama H, Brinkley WR, Sen S. The Aurora kinases: role in cell transformation and tumorigenesis. Cancer Metastasis Rev 22(4):451-64, 12/2003. PMID: 12884918.
5. Sen S. Aneuploidy and cancer. Curr Opin Oncol 12(1):82-8, 2000. PMID: 10687734.

Book Chapters

1. Sen S, Katayama H, Sasai K. Functional Significance of Aurora Kinase A in Centrosome Amplification & Genomic Instability. In: Hormonal Carcinogenesis (ed. Li JJ, Li SA, Mohla S, Rochefort H, Maudelonde T). 617, 99-108, 2008.
2. Sharma T, Cheong N, Sen P, Sen S. Constitutive heterochromatin and evolutionary divergence of Mus dunni, Mus booduga and Mus musculus. In: Current Topics in Microbiology and Immunology. Springer Verlag, 1986.

Grant & Contract Support

Title: Subcontract from the University of Maryland to validate Plasma miRNA and protein biomarkers for early detection of pancreatic cancer
Funding Source: University of Maryland - Baltimore
Role: Principal Investigator
Duration: 9/1/2011 - 8/31/2012
 
Title: Pre-validation and Validation of Pancreatic Ductal Adenocarcinoma Associated MicroRNA Networks in Exocrine Pancreatic Secretions and Blood
Funding Source: University of Maryland - Baltimore
Role: Principal Investigator
Duration: 9/1/2011 - 8/31/2012
 
Title: Genetic Pathways of Chromosomal Instability in Cancer: Identification of Novel Biomarkers and Therapeutic Targets
Funding Source: The University of Texas M.D. Anderson Cancer Center
Role: Principal Investigator
Duration: 9/1/2010 - 8/31/2012
 
Title: Aurora-A Oncoprotein Regulation of Mitochondrial Dynamics and Apoptosis Response.
Funding Source: NIH/NCI
Role: Principal Investigator

Last updated: 4/9/2013