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Sujit S. Prabhu, M.D., F.R.C.S. (Ed), FAANS

Present Title & Affiliation

Primary Appointment

Professor, Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX

Dual/Joint/Adjunct Appointment

Adjunct Associate Professor, Department of Neurosurgery, Division of Surgery, Baylor College of Medicine, Houston, TX

Bio Statement

Dr. Sujit Prabhu is an Associate Professor in the Department of Neurosurgery at MD Anderson Cancer Center and an Adjunct Associate Professorat the Baylor College of Medicine in Houston. He is very active clinically and has published at least 60 articles in peer reviewed journals.   His clinical interests are in the use of multimodality intraoperative monitoring techniques for the resection of brain tumors.  He has extensive experience with the use of the intraoperative MRI (iMRI) as a tool for the maximal safe resection of brain tumors.  He has published extensively on this subject and has advanced electrophysiological techniques in iMRI for tumor resection.  He has been an invited speaker at numerous national and international conferences.  He is a Fellow of the American Association of Neurological Surgeons (FAANS) and is an active member of the Congress of Neurological Surgeons (CNS) and the Society of Neurooncology (SNO).

Office Address

The University of Texas MD Anderson Cancer Center
Department of Neurosurgery
1400 Holcombe Blvd., FC7.2000
Unit Number: 442
Houston, TX 77030
Phone: (713) 792-2400
Fax: (713) 794-4950

Education & Training

Degree-Granting Education

1984 Government Medical College Bellary, Karnataka, India, MD, Medicine and Surgery

Postgraduate Training

8/2001-12/2002 Clinical Fellowship, Neurosurgical Oncology, Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, R. Sawaya, MD
7/1996-6/2001 Resident, Neurosurgery, Medical College of Virginia, Richmond, VA, H.F. Young, MD
2/1994-6/1996 Research Fellowship, Division of Neurosurgery, Medical College of Virginia, Richmond, VA, H.F. Young, MD
3/1991-7/1991 Research Fellowship, Neurosurgery, Derriford Hospital, Plymouth, England, Mr. J. Mohan, FRCS
10/1990-1/1991 Senior House Officer, Spinal Injuries, Lodge Moor Hospital, Sheffield, England, Mr. G. Ravichandran, FRCS
3/1989-9/1990 Senior House Officer, Surgery, Derriford Hospital, Plymouth, England, Mr. W. E. Strachan, FRCS
1/1988-2/1989 Senior House Officer, Orthopedics and Trauma/E.R., Morriston Hospital, Swansea, England, Mr. Dai Jones, FRCS
4/1987-9/1987 Resident Medical Officer, General Surgery, Medicine, and Emergency Medicine, Vinaya Clinic and Nursing Home, Mangalore, India, K. Devaiah, MD
10/1985-10/1986 Senior House Officer, General Surgery, General Surgery, Fr. Muller's Hospital, Mangalore, India, H.W. Furtado, MD
10/1984-9/1985 Intern, Rotating Internship, Fr. Muller's Hospital, Mangalore, India, H.W. Furtado, MD

Board Certifications

11/2007 American Board of Neurological Surgeons
6/1990 F.R.C.S., Fellow of the Royal College of Surgeons of Edinburgh


Academic Appointments

Associate Professor, Department of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 9/2008-8/2013

Honors and Awards

2006 Excellence in Teaching Award, The University of Texas Center for Biomedical Engineering Summer Internship Program
2005 Award of Appreciation, The University of Texas Center for Biomedical Engineering Summer Internship Program

Selected Publications

Peer-Reviewed Original Research Articles

1. Farnia B, Voong KR, Brown PD, Allen PK, Guha-Thakurta N, Prabhu SS, Rao G, Wang Q, Zhao Z, Mahajan A. Stereotactic radiosurgery for intraventricular brain metastases. J Neurosurg 121 Suppl:26-34, 12/2014. PMID: 25434934.
2. Maldaun MV, Khawja SN, Levine NB, Rao G, Lang FF, Weinberg JS, Tummala S, Cowles CE, Ferson D, Nguyen AT, Sawaya R, Suki D, Prabhu SS. Awake craniotomy for gliomas in a high-field intraoperative magnetic resonance imaging suite: analysis of 42 cases. J Neurosurg 121(4):810-817, 10/2014. e-Pub 8/2014. PMID: 25105702.
3. Trinh VT, Fahim DK, Maldaun MV, Shah K, McCutcheon IE, Rao G, Lang F, Weinberg J, Sawaya R, Suki D, Prabhu SS. Impact of Preoperative Functional Magnetic Resonance Imaging during Awake Craniotomy Procedures for Intraoperative Guidance and Complication Avoidance. Stereotact Funct Neurosurg 92(5). e-Pub 9/2014. PMID: 25247627.
4. Shahar T, Rozovski U, Marko NF, Tummala S, Ziu M, Weinberg JS, Rao G, Kumar VA, Sawaya R, Prabhu SS. Preoperative Imaging to Predict Intraoperative Changes in Tumor-to-Corticospinal Tract Distance: An Analysis of 45 Cases Using High-Field Intraoperative Magnetic Resonance Imaging. Neurosurgery 75(1):23-30, 7/2014. PMID: 24618800.
5. Kim BY, Jiang W, Beiko J, Prabhu SS, DeMonte F, Gilbert MR, Sawaya R, Aldape KD, Cahill DP, McCutcheon IE. Diagnostic discrepancies in malignant astrocytoma due to limited small pathological tumor sample can be overcome by IDH1 testing. J Neurooncol 118(2):405-12, 6/2014. e-Pub 4/29/2014. PMID: 24777756.
6. Hamilton JD, Rapp M, Marcel Schneiderhan T, Sabel M, Hayman A, Scherer A, Kröpil P, Budach W, Kretschmar U, Arne Gerber P, Prabhu S, Ginsberg LE, Bölke E, Matuschek C. Glioblastoma multiforme metastasis outside the CNS: Three case reports and possible mechanisms of escape. J Clin Oncol. e-Pub 2/2014.
7. Beiko J, Suki D, Hess KR, Fox BD, Cheung V, Cabral M, Shonka N, Gilbert MR, Sawaya R, Prabhu SS, Weinberg J, Lang FF, Aldape KD, Sulman EP, Rao G, McCutcheon IE, Cahill DP. IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resection. Neuro Oncol 16(1):81-91, 1/2014. e-Pub 12/2013. PMCID: PMC3870823.
8. Vabulas M, Kumar VA, Hamilton JD, Martinez JJ, Rao G, Sawaya R, Prabhu SS. Real-time atlas-based stereotactic neuronavigation. Neurosurgery 74(1):81-91, 1/2014. PMID: 24089050.
9. Kumar VA, Hamilton J, Hayman LA, Kumar AJ, Rao G, Weinberg JS, Sawaya R, Prabhu SS. Deformable Anatomic Templates (DAT) improve analysis of gliomas with minimal mass effect in eloquent areas. Neurosurgery 73(3):534-542, 9/2013. PMID: 23728447.
10. Wu AS, Trinh VT, Suki D, Graham S, Forman A, Weinberg JS, McCutcheon IE, Prabhu SS, Heimberger AB, Sawaya R, Wang X, Qiao W, Hess KR, Lang FF. A prospective randomized trial of perioperative seizure prophylaxis in patients with intraparenchymal brain tumors. J Neurosurg(118 (4)):873-83, 4/2013. PMID: 23394340.
11. Likhacheva A, Pinnix CC, Parikh NR, Allen PK, McAleer MF, Chiu MS, Sulman EP, Mahajan A, Guha-Thakurta N, Prabhu SS, Cahill DP, Luo D, Shiu AS, Brown PD, Chang EL. Predictors of survival in contemporary practice after initial radiosurgery for brain metastases. Int J Radiat Oncol Biol Phys 85(3):656-661, 3/2013. PMID: 22898384.
12. Walker GV, Gilbert MR, Prabhu SS, Brown PD, McAleer MF. Temozolomide use in adult patients with gliosarcoma: an evolving clinical practice. J Neurooncol 112(3):83-90, 3/2013. PMID: 23266723.
13. Trinh VT, Fahim DK, Shah K, Tummala S, McCutcheon IE, Sawaya R, Suki D, Prabhu SS. Subcortical injury is an independent predictor of worsening neurological deficits following awake craniotomy procedures. Neurosurgery 72(2):160-169, 2/2013. PMID: 23147778.
14. Likhacheva A, Pinnix CC, Parikh N, Allen PK, Guha-Thakurta N, McAleer M, Sulman EP, Mahajan A, Shiu A, Luo D, Chiu M, Brown PD, Prabhu SS, Chang EL. Validation of recursive partitioning analysis and diagnosis-specific graded prognostic assessment in patients treated initially with radiosurgery alone. J Neurosurg 117:38-44, 12/2012. PMID: 23205787.
15. Dziurzynski K, Blas-Boria D, Suki D, Cahill DP, Prabhu SS, Puduvalli V, Levine N. Butterfly glioblastomas: a retrospective review and qualitative assessment of outcomes. J Neurooncol 109(3):553-563, 9/2012. PMID: 22806339.
16. Hayman LA, Kumar VA, Hamilton J, Prabhu SS, Thiebaut de Schotten M, Al-Zubidi N, Pagani J, Vabulas M, Groneman M, Kumar AJ. Deformable anatomic templates embeds knowledge into patients brain images: Part 1. Construction and display. J Comput Assist Tomogr 36(3):354-359, May-Jun, 5/2012. PMID: 22592623.
17. Hamilton JD, Kumar VA, Hayman LA, Prabhu SS, Hou P, Jackson EF, Groneman M, Pagani J, Vabulas M, Kumar AJ. Deformable anatomic templates embed knowledge into brain images: Part 2. Validation using functional magnetic resonance imaging of the motor hand. J Comput Assist Tomogr 36(2):280-4, Mar-Apr, 3/2012. PMID: 22446375.
18. Schapiro R, Ferson D, Prabhu SS, Tummala S, Wefel J, Rao G. A technique for mapping cortical areas associated with speech arrest. Stereotact Funct Neurosurg 90(2):118-123, 2/2012. PMID: 22398728.
19. Tsung AJ, Prabhu SS, Lei X, Chern JJ, Benjamin Bekel N, Shonka NA. Cerebellar glioblastoma: a retrospective review of 21 patients at a single institution. J Neurooncol 105(3):552-562, 12/2011. PMID: 21643841.
20. Xu J, Sampath D, Lang FF, Prabhu S, Rao G, Fuller GN, Liu Y, Puduvalli VK. Vorinostat modulates cell cycle regulatory proteins in glioma cells and human glioma slice cultures. J Neurooncol 105(2):241-51, 11/2011. PMID: 21598070.
21. Dziurzynski K, Wei J, Qiao W, Hatiboglu MA, Kong LY, Wu A, Wang Y, Cahill D, Levine N, Prabhu S, Rao G, Sawaya R, Heimberger AB. Glioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotype. Clin Cancer Res 17(14):4642-9, 7/2011. PMID: 21490182.
22. Armstrong TS, Prabhu S, Aldape K, Hossan B, Kang S, Childress A, Tolentino L, Gilbert MR. A case of soft tissue metastasis from glioblastoma and review of the literature. J Neurooncol 103(1):167-172, 5/2011. PMID: 20809248.
23. Shonka NA, Armstrong TS, Prabhu SS, Childress A, Choi S, Langford LA, Gilbert MR. Atypical teratoid/rhabdoid tumors in adults: a case report and treatment-focused review. J Clin Med Res 3(2):85-92, 4/2011. PMID: 21811535.
24. Levin VA, Bidaut L, Hou P, Kumar AJ, Wefel JS, Bekele BN, Grewal J, Prabhu S, Loghin M, Gilbert MR, Jackson EF. Randomized double-blind placebo-controlled trial of bevacizumab therapy for radiation necrosis of the central nervous system. Int J Radiat Oncol Biol Phys 79(5):1487-95, 4/2011. PMID: 20399573.
25. Prabhu SS, Gasco J, Tummala S, Weinberg JS, Rao G. Intraoperative magnetic resonance imaging-guided tractography with integrated monopolar subcorical functional mapping for resection of brain tumors. J Neurosurg 114(3):719-726, 3/2011. PMID: 20964594.
26. Hassaneen W, Levine NB, Suki D, Salaskar AL, de Moura Lima A, McCutcheon IE, Prabhu SS, Lang FF, DeMonte F, Rao G, Weinberg JS, Wildrick DM, Aldape KD, Sawaya R. Multiple craniotomies in the management of multifocal and multicentric glioblastoma. Clinical article. J Neurosurg 114(3):576-84, 3/2011. PMID: 20690813.
27. Liu Y, Lang F, Xie X, Prabhu S, Xu J, Sampath D, Aldape K, Fuller G, Puduvalli VK. Efficacy of adenovirally expressed soluble TRAIL in human glioma organotypic slice culture and glioma xenografts. Cell Death Dis 2:e121, 2011. PMID: 21368892.
28. Prabhu SS, Bruner JM. Large oculomotor schwannoma presenting as a parasellar mass: A case report and literature review. Surg Neurol Int 1(15):15, 2010. PMID: 20657696.
29. Hatiboglu MA, Weinberg JS, Suki D, Tummala S, Rao G, Sawaya R, Prabhu SS. Utilization of intraoperative motor mapping in glioma surgery with high field intraoperative magnetic resonance imaging. Stereotact Funct Neurosurg 88(6):345-352, 2010. PMID: 20733348.
30. Hatiboglu MA, Weinberg JS, Suki D, Rao G, Prabhu SS, Shah K, Jackson E, Sawaya R. Impact of intraoperative high-field magnetic resonance imaging-guidance on glioma surgery: A prospective volumetric analysis. Neurosurgery 64(6):1073-81; discussion 1081, 6/2009. PMID: 19487886.
31. Kim SS, McCutcheon IE, Suki D, Weinberg JS, Sawaya R, Lang FF, Ferson D, Heimberger AB, DeMonte F, Prabhu SS. Awake craniotomy for brain tumors near eloquent cortex: Correlation of intraoperative cortical mapping with neurological outcomes in 309 consecutive patients. Neurosurgery 64(5):836-845, 5/2009. PMID: 19404147.
32. Gasco J, Franklin B, Fuller G, Salinas P, Prabhu S. Multifocal epithelioid glioblastoma multiforme mimicking cerebral metastasis: Case report. Neurocirugia (Astur) 20(6):550-4, 2009. PMID: 19967320.
33. Prabhu SS, Levine NB, Rao G, Shah K, Weinberg J. Report of negative diffusion –weighted MR imaging during tumor resections using intraoperative MRI. Stereotact Funct Neurosurg 87(5):304-308, 2009. PMID: 19641341.
34. Gasco J, Tummala S, Mahajan NM, Weinberg JS, Prabhu SS. Simultaneous use of functional tractography, neuronavigation-integrated subcortical white matter stimulation and intraoperative magnetic resonance imaging in glioma surgery: Technical note. Stereotact Funct Neurosurg 87(6):395-398, 2009. PMID: 19907203.
35. Jordan JT, Sun W, Hussain SF, DeAngulo G, Prabhu SS, Heimberger AB. Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy. Cancer Immunol Immunother 57(1):123-131, 2008. PMID: 17522861.
36. Golio DI, Prabhu S, Hauk EF, Esmaeli B. Surgical resection of locally advanced granular cell tumor of the orbit. J Craniofac Surg 17(3):594-598, 2006. PMID: 16770206.
37. Wang L, Wei Q, Wang LE, Aldape KD, Cao Y, Okcu MF, Hess KR, El-Zein R, Gilbert MR, Woo SY, Prabhu SS, Fuller GN, Bondy ML. Survival prediction in patients with glioblastoma multiforme by human telomerase genetic variation. J Clin Oncol 24(10):1627-1632, 2006. PMID: 16575014.
38. Chen ZJ, Gillies GT, Broaddus WC, Prabhu SS, Fillmore H, Mitchell RM, Corwin FD, Fatouros PP. A realistic brain tissue phantom for intraparenchymal infusion studies. J Neurosurg 101:314-322, 2004. PMID: 15309925.
39. Prabhu SS, Demonte F. Complete resection of a complex glomus jugulare tumor with extensive venous involvement. Case report. Neurosurg Focus 17:E12, 2004. PMID: 15329027.
40. Prabhu SS, Aldape KD, Bruner JM, Weinberg JS. Cowden disease with Lhermitte-Duclos disease: case report. Can J Neurol Sci 31:542-549, 2004. PMID: 15595264.
41. Maldaun MVC, Suki D, Lang FF, Prabhu SS, Shi W, Fuller GN, Wildrick DM, Sawaya R. Cystic glioblastoma multiforme: Survival outcomes in 22 cases. J Neurosurg 100:61-67, 2004. PMID: 14743913.
42. Prabhu SS, Diaz E, Sturgis EM, Myers JN, Suki D, DeMonte F. Section on tumors: Mahaley Clinical Research Award: Primary sarcomas of the skull base: An analysis of 63 cases. Clin Neurosurg 51:340-342, 2004. PMID: 15571164.
43. Han XY, Weinberg JS, Prabhu SS, Hassenbusch SJ, Fuller GN, Tarrand JJ, Kontoyiannis DP. Fusobacterial brain abscess: a review of five cases and an analysis of possible pathogenesis. J Neurosurg 99:693-700, 2003. PMID: 14567605.
44. Prabhu SS, Aldape KD, Gagel RF, Benjamin RS, Trent JC, McCutcheon IE. Sarcomatous change after sellar irradiation in a growth hormone-secreting pituitary adenoma. Can J Neurol Sci 30:378-383, 2003. PMID: 14672272.
45. Fourney DR, Prabhu SS, Cohen ZR, Rhines LD, Gokaslan ZL. Thoracolumbopelvic stabilization for the treatment of instability caused by recurrent myxopapillary ependymoma. J Spinal Disord Tech 16:108-111, 2003. PMID: 12571494.
Other Articles
1. Prabhu SS, Demonte F. Treatment of skull base tumors. Curr Opin Oncol 15:209-212, 2003. PMID: 12778013.
2. Olar A, Prabhu SS. Molecular classification of diffuse gliomas. Oncology(6):514, 518, 520, 6/2013.

Last updated: 12/8/2014