Susan L. McGovern, M.D., Ph.D.
Department of Radiation Oncology, Division of Radiation Oncology
About Dr. McGovern
Dr. Susan L. McGovern is an Associate Professor in Radiation Oncology at The University of Texas MD Anderson Cancer Center. She is currently a Radiation Oncologist in the CNS/Pedi Service. Her professional training and experience have prepared her well to the meningioma project as part of the U19 grant. During her residency at MD Anderson, she published a paper describing the uses and limitations of using photon radiation to treat meningioma. Her clinical practice includes treating children and adults with brain and spine tumors using a variety of modalities, including protons, and electrons. Some of her most challenging clinical cases have been patients with recurrent or high-grade meningiomas that are refractory to surgery and conventional radiation; more effective therapies are desperately needed for these patients. In her most recent research efforts she focused on analyzing our institutional experience with using proton therapy to treat aggressive tumors of the brain and spine. Dr. McGovern is the principal investigator of a prospective clinical trial at MD Anderson for reirradiation of recurrent brain tumors and she also serve on the institutional Clinical Research Committee, in which she reviews clinical protocols for scientific merit prior to IRB review. However, this experience has provided her with tremendous insight into the process of protocol design and has equipped her well for developing proton therapy as a treatment for meningiomas.
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Present Title & Affiliation
Primary Appointment
Medical Director, Proton Therapy Centers, Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Professor, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Associate Director of Pediatric Radiation Oncology, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX
Adjunct Faculty, Department of Pediatric Medicine/Hematology-Oncology, Texas Children’s Hospital, Houston, TX
Dual/Joint/Adjunct Appointment
Medical Director, Proton Therapy Centers, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Professor, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas
Adjunct Faculty, Department of Pediatric Medicine/Hematology-Oncology, Texas Children’s Hospital, Houston, TX
Education & Training
Degree-Granting Education
| 2005 | Northwestern University Medical School, Chicago, Illinois, US, MD |
| 2003 | Northwestern University, Evanston, Illinois, US, Biophysics and Structural Biology, Ph.D |
| 1997 | University of Notre Dame, South Bend, Indiana, US, Biochemistry and Mathematics, BS |
Postgraduate Training
| 2023-2023 | Six Sigma Advanced Yellow Belt, The University of Texas MD Anderson Cancer Center, Houston, Texas |
| 2018-2019 | Certificate, Health Care Management, Rice University, Houston, Texas |
| 2010-2011 | Research Fellowship, Structural Biology, Baylor College of Medicine, Houston, Texas |
| 2006-2010 | Clinical Residency, Radiation Oncology, UTMD Anderson Cancer Center, Houston, Texas |
| 2005-2006 | Clinical Internship, Internal Medicine, The University of Texas, Houston, Texas |
Board Certifications
| 2011 | American Board of Radiology |
Experience & Service
Academic Appointments
Ad Interim Medical Director, Proton Therapy Center, Department of Proton Therapy Center, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2024 - 2024
Associate Professor, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2024
Assistant Professor, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2018
Clinical Specialist, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - 2011
Administrative Appointments/Responsibilities
Ad Interim Medical Director, Proton Therapy Center, Department of Proton Therapy Center, The University of Texas MD Anderson Cancer Center, Houston, Texas, 2024 - Present
Co-Chair, The University of Texas MD Anderson Cancer Center, Mid-Career Faculty Promotion and Tenure Subcommittee, Houston, TX, 2023 - Present
Divisional Professionalism Ambassador, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - Present
Associate Medical Director, Proton Therapy Center, Department of Proton Therapy Center, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2024
Co-Chair, Department of Radiation Oncology, MRI Working Group,, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - 2020
Member, Synaptive Working Group, Houston, TX, 2018 - 2019
Co-Chair, Physician Peer Review, Working Group, Houston, TX, 2018 - 2019
Co-Chair, Pediatrics Working Group, Houston, TX, 2018 - Present
Associate Director of Pediatric Radiation Oncology, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - Present
Department of Radiation Oncology Main Building Clinical Backfill Committee, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2015
Other Appointments/Responsibilities
Pediatrics representative, ACR–ARS Practice Parameter for the Performance of Proton Beam Radiation Oncology, Reston, VA, 2022 - Present
Radiation Oncology Liaison, AYA Committee of the Children’s Oncology Group (COG), Chicago, IL, 2022 - Present
Advisory Board, Chimerix, Durham, NC, 2021 - 2022
Member, Children’s Oncology Group (COG) Long Term Follow Up Neurotoxicity Task Force, Philadelphia, PA, 2021 - Present
CNS and Pediatrics Radiation Oncology Consultant, MD Anderson Physician Network, Houston, 2016 - 2020
Physician surveyor, American College of Radiology Radiation Oncology Accreditation Program, Reston, VA, 2015 - 2019
CNS and Pediatrics Section Chair and Question Writer, American College of Radiology In-Training Exam, Reston, VA, 2014 - Present
Institutional Committee Activities
Physician Voting Member, Sedation & Procedures Committee, 2022 - Present
Member, Academic Leadership Team, 2020 - Present
Member, One RO Rebound and Recovery Plan Staffing Workstream, 2020 - 2020
Member, Interventional Radiology Chair Search Committee, 2020 - 2020
Faculty Representative, PRS Executive Council, 2019 - 2022
Member, Department of Radiation Oncology Grand Rounds Committee, 2019 - Present
Member, Brain and Spine Center Medical Director Search Committee, 2018 - 2018
Member, Data Safety Monitoring Board (DSMB), 2017 - Present
Member, Clinical Research Committee #1, 2014 - 2018
Honors & Awards
| Barry M. Goldwater Scholar | |
| Phi Beta Kappa | |
| Drug Discovery Program Symposium Best Poster, Northwestern University | |
| Medical Student Fellowship in Clinical Pharmacology, PhRMA Foundation | |
| Cellular and Molecular Basis of Disease Training Grant, National Institute of Health (NIH) | |
| Medical Scientist Training Program Training Grant, National Institute of Health (NIH) | |
| Presidential Fellow, Northwestern University | |
| Gramm Travel Fellowship, Robert H. Lurie Comprehensive Cancer Center | |
| Hot Paper in Chemistry, Thomson ISI | |
| NLM Training Program Biomedical Informatics | |
| Best Poster in Section, UTMD Anderson Cancer Center Annual Symposium in Cancer Research | |
| Best Postdoctoral Poster, Gulf Coast Consortia | |
| Fellow, Workshop in Methods in Clinical Cancer Research, Vail, Colorado | |
| Fellow, Workshop in Methods in Clinical Research, Vail, CO, July 2012 | |
| Recognizing May 2013 as Brain Tumor Awareness Month and commending Dr. Ronald A. DePinho, Dr. Charles A. Conrad, Dr. Jeffrey S. Weinberg, Dr. Susan McGovern, and the entire staff of The University of Texas MD Anderson Cancer Center, introduced by Rep. John Zerwas, passed May 2013, Texas House Resolution 1894 | |
| Cohort 2 of Faculty Academic Career Development Academy, CAO office, The University of Texas MD Anderson Cancer Center |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Ene, CI, Abi Faraj, C, Beckham, TH, Weinberg, J, Andersen, C, Haider, A, Rao, G, Ferguson, SD, Alvarez-Brenkenridge, CA, Kim, BY, Heimberger, AB, McCutcheon, IE, Prabhu, SS, Wang, CM, Ghia, AJ, McGovern, SL, Chung, C, McAleer, MF, Tom, MC, Perni, S, Swanson, T, Yeboa, DN, Briere, TM, Huse, J, Fuller, GN, Lang Jr, FF, Li, J, Suki, D, Sawaya, RE. Response of treatment-naive brain metastases to stereotactic radiosurgery. Nature communications 15(1), 2024. PMID: 38697991.
- McGovern SL, Paulino AC, Grippin AJ, Liu Y, Copling S, Nalin A, Crabtree K, Cheng H, Zhang Z, McAleer MF, Grosshans DR. Osteoradionecrosis in Pediatric Patients Treated with Proton Therapy for Head and Neck Malignancies. Int J Radiat Oncol Biol Phys None(None):None. e-Pub 2024. PMID: None.
- Gallitto M, Sedor G, Lee A, Pasetsky J, Kinslow CJ, Santos GL, Obiri-Yeboah D, Kshettry VR, Helis CA, Chan MD, Beckham TH, McGovern SL, Matsui J, Palmer JD, Bell JB, Mellon EA, Lakomy D, Huang J, Boor I, Rusthoven CG, Sisti MB, Wang TJC. Salvage Stereotactic Radiosurgery for Recurrent WHO Grade 2 and 3 Meningiomas: A Multicenter Study (STORM). Int J Radiat Oncol Biol Phys 120(3):730-737, 2024. e-Pub 2024. PMID: 38641234.
- McGovern SL, Lam K, Anderson CR, Marqueen K, Li J, Wang C, Majd NK, Aaroe AE, Loghin ME, O'Brien BJ. Early Outcomes from Proton Craniospinal Irradiation for Leptomeningeal Metastasis from Solid Tumors. Adv Radiat Oncol None(None):None. e-Pub 2024. PMID: None.
- Frank, SJ, Das, IJ, Simone, C, Davis, BJ, Deville, C, Liao, Z, Lo, SS, McGovern, SL, Parikh, RR, Reilly, M, Small, W, Schechter, NR. ACR-ARS Practice Parameter for the Performance of Proton Beam Therapy. International Journal of Particle Therapy 13, 2024. PMID: 39347377.
- Frank SJ, Das IJ, Simone II CB, Davis BJ, Deville C, Liao Z, Lo SS, McGovern SL, Parikh RR, Reilly M, Small Jr W, Schechter NR. ACR-ARS Practice Parameter for the Performance of Proton Beam Therapy. Intl J of Particle Therapy. e-Pub 2024. PMID: None.
- Lindsay HB, Scheurer ME, Allam AK, Lucas BJ, McGovern SL, Chintagumpala M, Paulino AC. Late-onset lymphopenia during radiation is associated with an increased risk of tumor recurrence in newly-diagnosed pediatric medulloblastoma. Pediatr Blood Cancer 71(7):e31022, 2024. e-Pub 2024. PMID: 38644606.
- Beckham TH, Rooney MK, McAleer MF, Ghia AJ, Tom MC, Perni S, McGovern SL, Grosshans DR, Chung C, Wang C, De B, Swanson T, Paulino A, Jiang W, Ferguson S, Patel CB, Li J, Yeboa DN. Hypofractionated radiotherapy for glioblastoma: A large institutional retrospective assessment of 2 approaches. Neurooncol Pract 11(3):266-274, 2024. e-Pub 2024. PMID: 38737610.
- Bronk JK, McAleer MF, McGovern SL, Lassen-Ramshad Y, Safwat A, Daw NC, Rainusso N, Mahajan A, Grosshans DR, Paulino AC. Comprehensive radiotherapy for pediatric Ewing Sarcoma: Outcomes of a prospective proton study. Radiother Oncol 195:110270, 2024. e-Pub 2024. PMID: 38583721.
- Abu-Arja MH, Brown AL, Su JM, Okcu MF, Lindsay HB, McGovern SL, McAleer MF, Grosshans DR, Chintagumpala MM, Paulino AC. The cochlear dose and the age at radiotherapy predict severe hearing loss after passive scattering proton therapy and cisplatin in children with medulloblastoma. Neuro Oncol. e-Pub 2024. PMID: 38916058.
- Mahajan A, Stavinoha PL, Rongthong W, Brodin NP, McGovern SL, El Naqa I, Palmer JD, Vennarini S, Indelicato DJ, Aridgides P, Bowers DC, Kremer L, Ronckers C, Constine L, Avanzo M. Neurocognitive Effects and Necrosis in Childhood Cancer Survivors Treated With Radiation Therapy: A PENTEC Comprehensive Review. Int J Radiat Oncol Biol Phys 119(2):401-416, 2024. e-Pub 2021. PMID: 33810950.
- Arrillaga-Romany I, Lassman A, McGovern SL, Mueller S, Nabors B, van den Bent M, Vogelbaum MA, Allen JE, Melemed AS, Tarapore RS, Wen PY, Cloughesy T. ACTION: A randomized phase 3 study of ONC201 (dordaviprone) in patients with newly diagnosed H3 K27M-mutant diffuse glioma. Neuro Oncol 26(Supplement_2):S173-S181, 2024. e-Pub 2024. PMID: 38445964.
- Wang C, Rooney MK, Alvarez-Breckenridge C, Beckham TH, Chung C, De BS, Ghia AJ, Grosshans DR, Majd NK, McAleer MF, McGovern SL, North RY, Paulino AC, Perni S, Reddy JP, Rhines LD, Swanson TA, Tatsui CE, Tom MC, Yeboa DN, Li J. Outcomes and Pattern of Care for Spinal Myxopapillary Ependymoma in the Modern Era-A Population-Based Observational Study. Cancers (Basel) 16(11), 2024. e-Pub 2024. PMID: 38893133.
- Odia Y, Koschmann C, Vitanza NA, de Blank P, Aguilera D, Allen J, Daghistani D, Hall M, Khatib Z, Kline C, MacDonald T, Mueller S, Faison SL, Allen JE, Naderer OJ, Ramage SC, Tarapore RS, McGovern SL, Khatua S, Zaky W, Gardner SL. Safety and pharmacokinetics of ONC201 (dordaviprone) administered two consecutive days per week in pediatric patients with H3K27M-mutant glioma. Neuro Oncol 26(Supplement_2):S155-S164, 2024. e-Pub 2024. PMID: 38400780.
- Aldave G, Okcu MF, Ruggieri L, Paulino AC, McGovern SL, Whitehead W, Weiner HL, Chintagumpala M. The role of surgery in recurrent ependymomas. J Neurosurg Pediatr 32(5):584-589, 2023. e-Pub 2023. PMID: 37657117.
- Ioakeim-Ioannidou M, Yeap BY, Flood T, Marinelli J, Giantsoudi D, Philip N, Tarbell NJ, Yock TI, Grosshans DR, McAleer MF, McGovern SL, MacDonald SM. Multi-Institutional Phase I Feasibility Trial of Vertebral Body Sparing CSI for Pediatric Brain Tumors. Int J Radiat Oncol Biol Phys 117(2S):e519-e520, 2023. PMID: 37785619.
- Nasr LF, Li J, Swanson TA, Ghia AJ, Wang C, Yeboa DN, Grosshans DR, McAleer MF, Beckham T, McGovern SL. Early Outcomes from Proton Craniospinal Irradiation (pCSI) for Leptomeningeal Disease from Solid Tumors. Int J Radiat Oncol Biol Phys 117(2S):e139-e140, 2023. PMID: 37784708.
- Grippin A, De B, Florez M, Tom MC, Beckham T, Wang C, Bishop AJ, Shanker MD, Li J, Amini B, Briere TM, Tatsui C, Rhines LD, McGovern SL, McAleer MF, Ghia AJ. Spine Stereotactic Radiosurgery for Primary and Metastatic Osteosarcoma. Int J Radiat Oncol Biol Phys 117(2S):e299, 2023. PMID: 37785092.
- Matsui JK, Allen PK, Perlow HK, Johnson JM, Paulino AC, McAleer MF, Fouladi M, Grosshans DR, Ghia AJ, Li J, Zaky W, Chintagumpala M, Palmer JD, McGovern SL. Prognostic Factors for Pediatric, Adolescent, and Young Adult Patients with Non-DIPG Grade 4 Gliomas: A Contemporary Pooled Institutional Experience. Int J Radiat Oncol Biol Phys 117(2S):e532, 2023. PMID: 37785650.
- Abu-Arja MH, Shatara MS, Okcu MF, McGovern SL, Su JM, Abdelbaki MS. The role of neoadjuvant chemotherapy in the management of metastatic central nervous system germinoma: A meta-analysis. Pediatr Blood Cancer 70(10):e30601, 2023. e-Pub 2023. PMID: 37501569.
- Sedor GJ, Lee AW, Gallitto M, Pasetsky J, Helis CA, Chan MD, Beckham T, McGovern SL, Wang TJC. Multi-Institutional Study of Stereotactic Radiosurgery for Recurrent WHO Grade 2/3 Meningiomas: An Interim Analysis. Int J Radiat Oncol Biol Phys 117(2S):e148, 2023. PMID: 37784728.
- Yeboa DN, Woodhouse K, Prabhu S, Li J, Beckham T, Weinberg JS, Wang C, McCutcheon IE, Swanson TA, Kim BYS, McGovern SL, North R, McAleer MF, Alvarez-Breckenridge C, Jiang W, Ene C, Ejezie CL, Lang F, Rao G, Ferguson S. MD Anderson Phase III Randomized Preoperative Stereotactic Radiosurgery (SRS) vs. Postoperative SRS for Brain Metastases Trial. Int J Radiat Oncol Biol Phys 117(2S):e160-e161, 2023. PMID: 37784756.
- Rubino F, Schur S, McGovern SL, Kamiya-Matsuoka C, DeMonte F, Raza SM. Impact of salvage surgery with or without reirradiation for skull base meningiomas recurring after prior radiotherapy. J Neurosurg 139(3):798-809, 2023. e-Pub 2023. PMID: 36738459.
- Matsui JK, Allen PK, Perlow HK, Johnson JM, Paulino AC, McAleer MF, Fouladi M, Grosshans DR, Ghia AJ, Li J, Zaky WT, Chintagumpala MM, Palmer JD, McGovern SL. Prognostic Factors for Pediatric, Adolescent, and Young Adult Patients with Non- DIPG Grade 4 Gliomas: A Contemporary Pooled Institutional Experience. J Neurooncol 163(3):717-726, 2023. e-Pub 2023. PMID: 37440097.
- Altan M, Wang Y, Song J, Welsh J, Tang C, Guha-Thakurta N, Blumenschein GR, Carter BW, Wefel JS, Ghia AJ, Yeboa DN, McAleer MF, Chung C, Woodhouse KD, McGovern SL, Wang C, Kim BYS, Weinberg JS, Briere TM, Elamin YY, Le X, Cascone T, Negrao MV, Skoulidis F, Ferrarotto R, Heymach JV, Li J. Nivolumab and ipilimumab with concurrent stereotactic radiosurgery for intracranial metastases from non-small cell lung cancer: analysis of the safety cohort for non-randomized, open-label, phase I/II trial. J Immunother Cancer 11(7), 2023. PMID: 37402581.
- Hasanov M, Milton DR, Davies AB, Sirmans E, Saberian C, Posada EL, Opusunju S, Gershenwald JE, Torres-Cabala CA, Burton EM, Colen RR, Huse JT, Glitza Oliva IC, Chung C, McAleer MF, McGovern SL, Yeboa DN, Kim BYS, Prabhu SS, McCutcheon IE, Weinberg JS, Lang FF, Tawbi HA, Li J, Haydu LE, Davies MA, Ferguson SD. Changes In Outcomes And Factors Associated With Survival In Melanoma Patients With Brain Metastases. Neuro Oncol 25(7):1310-1320, 2023. e-Pub 2022. PMID: 36510640.
- Cao W, Li Y, Zhang X, Poenisch F, Yepes P, Sahoo N, Grosshans DR, McGovern SL, Gunn GB, Frank SJ, Zhu XR. Intensity modulated proton arc therapy via geometry-based energy selection for ependymoma. J Appl Clin Med Phys 24(7):e13954, 2023. e-Pub 2023. PMID: 36913484.
- Aldave G, Okcu MF, Chintagumpala M, Ruggieri L, Minard CG, Malbari F, Mash LE, Paulino AC, McGovern SL, Ramaswamy U, Whitehead W, Kahalley LS. Comparison of neurocognitive and quality-of-life outcomes in pediatric craniopharyngioma patients treated with partial resection and radiotherapy versus gross-total resection only. J Neurosurg Pediatr 31(5):453-462, 2023. e-Pub 2023. PMID: 36806176.
- Pokhylevych H, Khose S, Gule-Monroe MK, Chen MM, Fuller G, Gruschkus SK, Sadighi Z, Zaky W, Sandberg DI, McGovern SL, Johnson JM. Contrast enhancement patterns in pediatric glioblastomas. J Comput Assist Tomogr 47(1):115-120, 2023. e-Pub 2022. PMID: 36112052.
- Chevli N, Grosshans DR, McAleer MF, Foster JH, Harrison D, McGovern SL, Paulino AC. Renal function in abdominal neuroblastoma patients undergoing proton radiotherapy. Pediatr Blood Cancer 70(1):e29981, 2023. e-Pub 2022. PMID: 36129239.
- De B, Florez MA, Ludmir EB, Maor MH, McGovern SL, McAleer MF, Grosshans DR, Chang EL, Mahajan A, Paulino AC. Late Effects of Craniospinal Irradiation Using Electron Spinal Fields for Pediatric Cancer Patients. Int J Radiat Oncol Biol Phys 115(1):164-173, 2023. e-Pub 2022. PMID: 35716848.
- McGovern SL, Luo D, Johnson J, Nguyen K, Li J, McAleer MF, Yeboa D, Grosshans DR, Ghia AJ, Chung C, Bishop AJ, Song J, Thall PF, Brown PD, Mahajan A. A Prospective Study of Conventionally Fractionated Dose Constraints for Re-Irradiation of Primary Brain Tumors in Adults. Pract Radiat Oncol 13(3):231-238, 2023. e-Pub 2022. PMID: 36596356.
- Gregory TA, Mastall M, Lin H, Hess KR, Yuan Y, Martin-Bejarano Garcia M, Fuller GN, Alfaro KD, Gule-Monroe MK, Huse JT, Khatua S, Rao G, Sandberg DI, Wefel JS, Yeboa DN, Paulino AC, McGovern SL, Zaky W, Mahajan A, Suki D, Weathers SP, Harrison RA, de Groot JF, Puduvalli VK, Penas-Prado M, Majd NK. Characterization of recurrence patterns and outcomes of medulloblastoma in adults: The University of Texas MD Anderson Cancer Center experience. Neurooncol Adv 5(1):vdad032, 2023. e-Pub 2023. PMID: 37114244.
- Upadhyay R, Liao K, Grosshans DR, McGovern SL, Frances McAleer M, Zaky W, Chintagumpala MM, Mahajan A, Nana Yeboa D, Paulino AC. Quantifying the risk and dosimetric variables of symptomatic brainstem injury after proton beam radiation in pediatric brain tumors. Neuro Oncol 24(9):1571-1581, 2022. e-Pub 2022. PMID: 35157767.
- Gardner SL, Tarapore RS, Allen J, McGovern SL, Zaky W, Odia Y, Daghistani D, Diaz Z, Hall M, Khatib Z, Koschmann C, Cantor E, Kurokawa R, MacDonald TJ, Aguilera D, Vitanza NA, Mueller S, Kline C, Lu G, Allen J, Khatua S. Phase 1 dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy. Neuro-Oncol Adv 13(4):vdac143, 2022. PMID: 36382108.
- Bishop AJ, Zheng J, Subramaniam A, Ghia AJ, Wang C, McGovern SL, Patel S, Guadagnolo BA, Mitra D, Farooqi A, Reardon MJ, Kim B, Guha-Thakurta N, Li J, Ravi V. Cardiac angiosarcomas: risk of brain metastasis and hemorrhage warrants frequent surveillance imaging and early intervention. Am J Clin Oncol 45(6):258-263, 2022. e-Pub 2022. PMID: 35588225.
- Agarwal S, Cortes-Santiago N, Scheurer M, Bhar S, Martinez C, Sartain S, McGovern SL. Diffuse Alveolar Hemorrhage: An underreported complication of Transplant associated Thrombotic Microangiopathy. Bone Marrow Transplant 57(6):889-895, 2022. e-Pub 2022. PMID: 35352036.
- Upadhyay R, Khose S, Pokhylevych H, Paulino AC, McAleer MF, Ghia A, Li J, Yeboa DN, Loghin M, Harrison R, O'Brien B, Kamiya-Matsuoka C, De Groot J, Puduvalli VK, Tatsui C, Alvarez-Breckenridge C, Prabhu S, Rhines L, Zaky W, Lin F, Weinberg JS, Fuller G, Sandberg DI, Johnson JM, McGovern SL. Patterns of failure after radiation therapy in primary spinal high-grade gliomas: A single institutional analysis. Neurooncol Adv 4(1):vdac129, 2022. e-Pub 2022. PMID: 36128585.
- Gardner SL, Tarapore RS, Allen J, McGovern SL, Zaky W, Odia Y, Daghistani D, Diaz Z, Hall MD, Khatib Z, Koschmann C, Cantor E, Kurokawa R, MacDonald TJ, Aguilera D, Vitanza NA, Mueller S, Kline C, Lu G, Allen JE, Khatua S. Phase I dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy. Neurooncol Adv 4(1):vdac143, 2022. e-Pub 2022. PMID: 36382108.
- Bronk JK, Hou P, Amsbaugh MJ, Khatua S, Mahajan A, Ketonen L, McGovern SL. Sequential diffusion tensor imaging and magnetic resonance spectroscopy in patients undergoing re-irradiation for progressive diffuse intrinsic pontine glioma. Adv Radiat Oncol 7(2):100847, 2021. PMID: 35071836.
- Paulino AC, Ludmir EB, Grosshans DR, Su JM, McGovern SL, Okcu MF, McAleer MF, Baxter PA, Mahajan A, Chintagumpala MM. Overall Survival and Secondary Malignant Neoplasms in Children Receiving Passively Scattered Proton or Photon Craniospinal Irradiation for Medulloblastoma. Cancer 127(20):3865-3871, 2021. e-Pub 2021. PMID: 34254296.
- Wilmas KM, Garner WB, Ballo MT, McGovern SL, MacFarlane DF. The role of radiation therapy in the management of cutaneous malignancies.Part II: When is radiation therapy indicated?. J Am Acad Dermatol 85(3):551-562, 2021. e-Pub 2021. PMID: 34116100.
- Whitlock, RS, Mehl, SC, Chelius, D, Koshy, J, Mills, JL, Ongkasuwan, J, McGovern, SL, Okcu, MF, Naik-Mathuria, B. Complex multidisciplinary resection of a malignant rhabdoid tumor of the neck & mediastinum in a pediatric patient. Journal of Pediatric Surgery Case Reports 71, 2021. PMID: None.
- Brown PD, Chung C, Liu DD, McAvoy S, Grosshans DR, Al Feghali K, Mahajan A, Li J, McGovern SL, McAleer MF, Ghia AJ, Sulman EP, Penas-Prado M, de Groot JF, Heimberger AB, Wang J, Armstrong TS, Gilbert MR, Guha-Thakurta N, Wefel JS. A prospective phase II randomized trial of proton radiotherapy vs intensity-modulated radiotherapy for patients with newly diagnosed glioblastoma. Neuro-Oncol 23(8):1337-1347, 2021. PMID: 33647972.
- Bishop AJ, Livingston JA, Ning MS, Valdez ID, Wages CA, McAleer MF, Paulino AC, Grosshans DR, Woodhouse KD, Tao R, Roth ME, Gunn GB, McGovern SL. Young Adult Populations Face yet another Barrier to Care with Insurers: Limited Access to Proton Therapy. Int J Radiat Oncol Biol Phys 110(5):1496-1504, 2021. e-Pub 2021. PMID: 33677051.
- Hanania AN, Paulino AC, Ludmir EB, Shah VS, Su JM, McGovern SL, Baxter PA, McAleer MF, Grosshans DR, Okcu MF, Chintagumpala MM. Early Radiotherapy Preserves Vision in Sporadic Optic Pathway Glioma. Cancer 127(13):2358-2367, 2021. e-Pub 2021. PMID: 33739455.
- Nantavithya C, Paulino AC, Liao K, Woodhouse KD, McGovern SL, Grosshans DR, McAleer MF, Khatua S, Chintagumpala MM, Majd N, Zaky W, Yeboa DN. Observed-to-expected incidence ratios of second malignant neoplasms after radiation therapy for medulloblastoma: A surveillance, epidemiology, and end results analysis. Cancer 127(13):2368-2375, 2021. e-Pub 2021. PMID: 33721338.
- Spiotto MT, McGovern SL, Gunn GB, Grosshans D. Proton Radiotherapy to Reduce Late Complications in Childhood Head and Neck Cancers. International Journal of Particle Therapy 8(1):155-167, 2021. PMID: 34285943.
- Majd NK, Mastall M, Lin H, Dibaj SS, Hess KR, Yuan Y, Garcia MM, Fuller GN, Alfaro KD, Gule-Monroe MK, Huse JT, Khatua S, Rao G, Sandberg DI, Wefel JS, Yeboa DN, Paulino AC, McGovern SL, Zaky W, Mahajan A, Suki D, Weathers SP, Harriso RA, De Groo JF, Puduvalli VK, Penas-Prado M. Clinical characterization of adult medulloblastoma and the effect of first-line therapies on outcome; The MD Anderson Cancer Center experience. Neurooncol Adv 3(1):vdab079, 2021. e-Pub 2021. PMID: 34377987.
- Ravindra VM, Okcu MF, Ruggieri L, Frank TS, Paulino AC, McGovern SL, Horne VE, Dauser RC, Whitehead WE, Aldave G. Comparison of multimodal surgical and radiation treatment methods for pediatric craniopharyngioma: long-term analysis of progression-free survival and morbidity. J Neurosurg Pediatr 28(2):152-159, 2021. e-Pub 2021. PMID: 34049281.
- Yechieli RL, Mandeville HC, Hiniker SM, Bernier-Chastagner V, McGovern SL, Scarzello G, Wolden S, Cameron A, Breneman J, Fajardo RD, Donaldson SS. Rhabdomyosarcoma. Pediatr Blood Cancer 68(S2), 2021. e-Pub 2021. PMID: 33818882.
- Thrower SL, Al Feghali KA, Luo D, Paddick I, Hou P, Briere T, Li J, McAleer MF, McGovern SL, Woodhouse KD, Yeboa DN, Brock KK, Chung C. The Effect of Slice Thickness on Contours of Brain Metastases for Stereotactic Radiosurgery. Advances in Radiation Oncology 6(4):100708, 2021. e-Pub 2021. PMID: 34124413.
- Buszek SM, Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Disease Control and Patterns of Failure After Proton Beam Therapy for Rhabdomyosarcoma. Int J Radiat Oncol Biol Phys 109(3):718-725, 2021. PMID: 33516439.
- Mohan R, Liu AY, Brown PD, Mahajan A, Dinh J, Chung C, McAvoy S, McAleer MF, Lin SH, Li J, Ghia AJ, Zhu C, Sulman EP, de Groot JF, Heimberger AB, McGovern SL, Grassberger C, Shih H, Ellsworth S, Grosshans DR. Proton Therapy Reduces the Likelihood of High-Grade Radiation-Induced Lymphopenia in Glioblastoma Patients: Phase II Randomized Study of Protons vs. Photons. Neuro Oncol 23(2):284-294, 2021. e-Pub 2020. PMID: 32750703.
- Al Feghali KA, Randall JW, Liu DD, Wefel JS, Brown PD, Grosshans DR, McAvoy SA, Farhat MA, Li J, McGovern SL, McAleer MF, Ghia AJ, Paulino AC, Sulman EP, Penas-Prado M, Wang J, de Groot J, Heimberger AB, Armstrong TS, Gilbert MR, Mahajan A, Guha-Thakurta N, Chung C. Phase II trial of proton therapy versus photon IMRT for GBM: secondary analysis comparison of progression-free survival between RANO versus clinical assessment. Neurooncol Adv 3(1):vdab073, 2021. e-Pub 2021. PMID: 34337411.
- Mak DY, Laperriere N, Ramaswamy V, Bouffet E, Murray JC, McNall-Knapp RY, Bielamowicz K, Paulino AC, Zaky W, McGovern SL, Okcu MF, Tabori U, Atwi D, Dirks PB, Taylor MD, Tsang DS, Bavle A. Reevaluating surgery and re-irradiation for locally recurrent pediatric ependymoma-a multi-institutional study. Neurooncol Adv 3(1):vdab158, 2021. e-Pub 2021. PMID: 34988448.
- Liu SM, Brooks ED, Rubin ML, Consortium MD, Grosshans DR, Frank SJ, McAleer MF, McGovern SL, Paulino AC, Woodhouse KD. Referral Patterns and Treatment Delays in Medulloblastoma: A Large Academic Proton Center Experience. Int J Part Ther 7(3):1-10, 2021. e-Pub 2020. PMID: 33604411.
- Lin TA, Ludmir EB, Liao KP, McAleer MF, Bishop AJ, Grosshans D, McGovern SL, Woodhouse KD, Paulino AC, Yeboa DN. Relationship between treatment center case volume and survival for localized Ewing sarcoma: The role of radiotherapy timing. Pediatr Blood Cancer 67(11):e28685, 2020. e-Pub 2020. PMID: 32881378.
- Anakwenze CP, McGovern SL, Taku N, Liao K, Boyce-Fappiano DR, Kamiya-Matsuoka C, Ghia A, Chung C, Trifiletti D, Ferguson SD, Li J, Yeboa DN. Association Between Facility Volume and Overall Survival for Patients with Grade II Meningioma after Gross Total Resection. World Neurosurg 141:e133-e144, 2020. e-Pub 2020. PMID: 32407910.
- McGovern SL, Wages C, Dimmitt A, Sanders C, Martin D, Ning MS, Manning R, Amin M, Zhu RX, Frank SJ, Gunn GB. Proton therapy in a pandemic: An operational response to the COVID-19 crisis. Int J Part Ther 7(1):54-57, 2020. PMID: 33094136.
- Trifiletti DM, Malouff TD, McGovern SL, Weathers SP, Wang TJC, Lassman AB, Cahill DP, Shih HA, Brown PD. Repeat radiation in the brain: managing patients with locally recurrent glioma. Semin Radiat Oncol 30(3):218-222, 2020. PMID: None.
- Noticewala SS, Ludmir EB, Bishop AJ, Chung C, Ghia AJ, Grosshans D, McGovern SL, Paulino AC, Wang C, Woodhouse KD, Yeboa DN, Prabhu SS, Weathers SP, Das P, Koong AC, McAleer MF, Li J. Radiation for Glioblastoma in the Era of Coronavirus Disease 2019 (COVID-19): Patient Selection and Hypofractionation to Maximize Benefit and Minimize Risk. Adv Radiat Oncol 5(4):743-745, 2020. e-Pub 2020. PMID: 32775785.
- Nantavithya C, Paulino AC, Liao K, McGovern SL, Grosshans DR, McAleer MF, Woodhouse KD, Khatua S, Chintagumpala MM, Majd NK, Yeboa DN. Development of second primary tumors and outcomes in medulloblastoma by treatment modality: A Surveillance, Epidemiology, and End Results analysis. Pediatr Blood Cancer:e28373. e-Pub 2020. PMID: 32453481.
- Sa HS, Rubin ML, Ning J, Li W, Tetzlaff MT, McGovern SL, Paulino AC, Herzog CE, Gill JB, Esmaeli B. Association of T and N Categories of the American Joint Commission on Cancer, 8th Edition, With Metastasis and Survival in Patients With Orbital Sarcoma. JAMA Ophthalmol 138(4):374-381, 2020. e-Pub 2020. PMID: 32105303.
- Esmaeli, B, Rubin, L, Ning, J, Tetzlaff, M, Li, W, McGovern, SL, Paulino, A, Herzog, CE, Gill, JB. Correlation of T and N Categories of the AJCC 8th-Edition Classification with Metastasis and Survival in Patients with Orbital Sarcoma. JAMA Ophthalmol, 2020. PMID: None.
- Buszek SM, Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Patterns of failure and toxicity profile following proton beam therapy for pediatric bladder and prostate rhabdomyosarcoma. Pediatr Blood Cancer 66(11):e27952, 2019. e-Pub 2019. PMID: 31397065.
- Bagley AF, Grosshans DR, Philip NV, Foster J, McAleer MF, McGovern SL, Lassen-Ramshad Y, Mahajan A, Paulino AC. Efficacy of proton therapy in children with high-risk and locally recurrent neuroblastoma. Pediatric Blood & Cancer 66(8):e27786, 2019. e-Pub 2019. PMID: 31050179.
- Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Patterns of Failure following Proton Beam Therapy for Head and Neck Rhabdomyosarcoma. Radiother Oncol 134:143-150, 2019. e-Pub 2019. PMID: 31005208.
- Amsbaugh MJ, Mahajan A, Thall PF, McAleer MF, Paulino AC, Grosshans D, Khatua S, Ketonen L, Fontanilla H, McGovern SL. A Phase 1/2 Trial of Reirradiation for Diffuse Intrinsic Pontine Glioma. Int J Radiat Oncol Biol Phys 104(1):144-148, 2019. e-Pub 2019. PMID: 30610915.
- Buszek SM, Ikner S, Wiedemann L, Wang J, McAleer MF, Grosshans DR, Paulino AC, McGovern SL, Chung C. Safety and Feasibility of Magnetic Resonance Imaging Simulation for Radiation Treatment Planning in Pediatric Patients: A Single Institution Experience. Adv Radiat Oncol 4(2):362-366, 2019. e-Pub 2018. PMID: 31011682.
- Jaramillo S, Grosshans DR, Philip N, Varan A, Akyüz C, McAleer MF, Mahajan A, McGovern SL. Radiation for ETMR: Literature review and case series of patients treated with proton therapy. Clin Transl Radiat Oncol 15:31-37, 2019. e-Pub 2018. PMID: 30582019.
- Ludmir EB, Mahajan A, Paulino AC, Jones JY, Ketonen LM, Su JM, Grosshans DR, McAleer MF, McGovern SL, Lassen-Ramshad YA, Adesina AM, Dauser RC, Weinberg JS, Chintagumpala MM. Increased Risk of Pseudoprogression among Pediatric Low-Grade Glioma Patients Treated with Proton versus Photon Radiotherapy. Neuro Oncol. e-Pub 2019. PMID: 30753704.
- Lin TA, Ludmir EB, Liao KP, McAleer MF, Grosshans DR, McGovern SL, Bishop AJ, Woodhouse KD, Paulino AC, Yeboa DN. Timing of Local Therapy Impacts Survival in Ewing Sarcoma. Int J Radiat Oncol Biol Phys. e-Pub 2018. PMID: 30593906.
- Paulino AC, Mahajan A, Ye R, Grosshans DR, Okcu MF, Su J, McAleer MF, McGovern SL, Mangona VA, Chintagumpala M. Ototoxicity and Cochlear Sparing in Children with Medulloblastoma: Proton vs. Photon Radiotherapy. Radiotherapy and Oncology 128(1):128-132, 2018. e-Pub 2018. PMID: 29373195.
- Zhang Z, Yang J, Ho A, Jiang W, Logan J, Wang X, Brown PD, McGovern SL, Guha-Thakurta N, Ferguson SD, Fave X, Zhang L, Mackin D, Court LE, Li J. A predictive model for distinguishing radiation necrosis from tumour progression after gamma knife radiosurgery based on radiomic features from MR images. Eur Radiol 28(6):2255-2263, 2018. e-Pub 2017. PMID: 29178031.
- Weber DC, Habrand JL, Hoppe BS, Hill Kayser C, Laack NN, Langendijk JA, MacDonald SM, McGovern SL, Pater L, Perentesis JP, Thariat J, Timmerman B, Yock TI, Mahajan A. Proton therapy for pediatric malignancies: Fact, figures and costs. A joint consensus statement from the pediatric subcommittee of PTCOG, PROS and EPTN. Radiother Oncol, 2018. PMID: 29937209.
- Ludmir EB, Paulino AC, Grosshans DR, McAleer MF, McGovern SL, Huh WW, Okcu MF, Harrell LM, Mahajan A. Regional Nodal Control for Head and Neck Alveolar Rhabdomyosarcoma. Int J Radiat Oncol Biol Phys 101(1):169-176, 2018. e-Pub 2018. PMID: 29477293.
- Duman JG, Dinh J, Zhou W, Cham H, Mavratsas VC, Paveškovic M, Mulherkar S, McGovern SL, Tolias KF, Grosshans DR. Memantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses. Neuro Oncol 20(5):655-665, 2018. e-Pub 2017. PMID: 29112734.
- Prayongrat A, Tao R, Allen PK, Guha N, Rao G, Zhao Z, Li J, Brown PD, McGovern SL. Outcomes of Stereotactic radiosurgery of brain metastases from neuroendocrine tumors. Neurooncol Pract 5(1):37-45, 2018. e-Pub 2017. PMID: 31385968.
- Bronk JK, Guha-Thakurta N, Allen PK, Mahajan A, Grosshans DR, McGovern SL. Analysis of pseudoprogression after proton or photon therapy of 99 patients with low grade and anaplastic glioma. Clin Transl Radiat Oncol 9:30-34, 2018. e-Pub 2018. PMID: 29594248.
- Mahajan A, Ahmed S, McAleer MF, Weinberg JS, Li J, Brown P, Settle S, Prabhu SS, Lang FF, Levine N, McGovern SL, Sulman E, McCutcheon IE, Azeem S, Cahill D, Tatsui C, Sawaya R, Hess KR, Rao G. Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial. Lancet Oncol 18(8):1040-1048, 2017. e-Pub 2017. PMID: 28687375.
- Farnia B, Philip N, Georges RH, McAleer MF, Palmer M, Yang J, Allen PK, Martel MK, Mahajan A, McGovern SL. Reirradiation of recurrent pediatric brain tumors after initial proton therapy. Int J Part Ther 3(1):1-12, 2016. PMID: None.
- Greenfield BJ, Jaramillo S, Abboud M, Mahajan A, Paulino AC, McGovern SL, McAleer MF, Chintagumpala M, Faith Okcu M, Khatua S, Su J, Grosshans DR. Outcomes for pediatric patients with central nervous system germ cell tumors treated with proton therapy. Clin Transl Radiat Oncol 1:9-14, 2016. PMID: None.
- Grossberg A, Zhao Z, Walker G, Tsai J, Wang X, Lang F, Phan J, Ghia A, McGovern SL, Mahajan A, Brown P, McAleer MF, Li J. Dose painting with Gamma Knife: Two techniques for delivering different doses to areas of recurrent or residual tumor after resection of brain metastases. Pract Radiat Oncol 5(6):390-397, 2015. e-Pub 2015. PMID: 26412338.
- Lassen-Ramshad Y, Petersen JB, Tietze A, Borghammer P, Mahajan A, McGovern SL. Pseudoprogression after proton radiotherapy for pediatric low grade glioma. Acta Oncol 54(9):1701-2, 2015. e-Pub 2015. PMID: 26368788.
- Grant SR, Grosshans DR, Bilton SD, Garcia JA, Amin M, Chambers MS, McGovern SL, McAleer MF, Morrison WH, Huh WW, Kupferman ME, Mahajan A. Proton versus conventional radiotherapy for pediatric salivary gland tumors: Acute toxicity and dosimetric characteristics. Radiother Oncol 116(2):309-15, 2015. e-Pub 2015. PMID: 26232128.
- McGovern SL, Grosshans D, Mahajan A. Embryonal brain tumors. Cancer J 20(6):397-402, 2014. PMID: 25415685.
- Bishop AJ, Greenfield B, Mahajan A, Paulino AC, Okcu MF, Allen PK, Chintagumpala M, Kahalley LS, McAleer MF, McGovern SL, Whitehead WE, Grosshans DR. Proton Beam Therapy Versus Conformal Photon Radiation Therapy for Childhood Craniopharyngioma Multi-institutional Analysis of Outcomes, Cyst Dynamics and Toxicity. Int J Radiat Oncol Biol Phys 90(2):354-361, 2014. e-Pub 2014. PMID: 25052561.
- Grosshans, DR, Zhu, XR, Melancon, A, Allen, PK, Poenisch, F, Palmer, M, McAleer, MF, McGovern SL, Gillin, M, DeMonte, F, Chang, EL, Brown, PD, Mahajan A, A. Spot scanning proton therapy for malignancies of the base of skull: treatment planning, acute toxicities, and preliminary clinical outcomes. Int J Radiat Oncol Biol Phys 90(3):540-546, 2014. PMID: 25304948.
- Okcu MS, Munsell, MF, Kumbalasseriyil, N, Grosshans, DR, McAleer, MF, Chintagumpala, M, Khatua, S, Mahajan A, McGovern SL. Outcomes and acute toxicities of proton therapy for pediatric atypical teratoid/rhabdoid tumor of the central nervous system. Int J Radiat Oncol Biol Phys None(14):4061-9. e-Pub 2014. PMID: 25311260.
- Welsh JW, Komaki R, Amini A, Munsell MF, Unger W, Allen PK, Chang JY, Wefel JS, McGovern SL, Chen SS, Holt J, Liao Z, Brown P, Sulman E, Heymach JV, Kim ES, Stea B, Garland LL. Phase II Trial of Erlotinib plus Concurrent Whole-Brain Radiation Therapy for Patients with Brain Metastases from Non-Small Cell Lung Cancer. J Clin Oncol None(None):None. e-Pub 2013. PMID: 23341526.
- McGovern SL, Qi Y, Pusztai L, Symmans WF, Buchholz TA. CENP-A, an essential centromere protein, is a prognostic marker for relapse in estrogen receptor-positive breast cancer. Breast Cancer Res 14(3):R72. e-Pub 2012. PMID: 22559056.
- McGovern SL, Aldape KD, Munsell MF, Mahajan A, DeMonte F, Woo SY. A comparison of World Health Organization tumor grades at recurrence in patients with non-skull base and skull base meningiomas. J Neurosurg 112(5):925-33, 2010. PMID: 19799498.
- McGovern SL, Liao Z, Bucci MK, McAleer MF, Jeter MD, Chang JY, O'Reilly MS, Cox JD, Allen PK, Komaki R. Is sex associated with the outcome of patients treated with radiation for nonsmall cell lung cancer?. Cancer 115(14):3233-242, 2009. PMID: 19472405.
- Diehn M, Nardini C, Wang DS, McGovern SL, Jayaraman M, Liang Y, Aldape K, Cha S, Kuo MD. Identification of noninvasive imaging surrogates for brain tumor gene-expression modules. Proceedings of the National Academy of Sciences 105:5213-218, 2008. PMID: None.
- Seidler J, McGovern SL, Doman TN, Shoichet BK. Identification and prediction of promiscuous aggregating inhibitors among known drugs. J Med Chem 46(21):4477-486, 2003. PMID: 14521410.
- McGovern SL, Helfand BT, Feng B, Shoichet BK. A specific mechanism of nonspecific inhibition. J Med Chem 46(20):4265-272, 2003. PMID: 13678405.
- McGovern SL, Shoichet BK. Information decay in molecular docking screens against holo, apo, and modeled conformations of enzymes. J Med Chem 46(14):2895-907, 2003. PMID: 12825931.
- McGovern SL, Shoichet BK. Kinase inhibitors: not just for kinases anymore. J Med Chem 46(8):1478-483, 2003. PMID: 12672248.
- Doman TN, McGovern SL, Witherbee BJ, Kasten TP, Kurumbail R, Stallings WC, Connolly DT, Shoichet BK. Molecular docking and high-throughput screening for novel inhibitors of protein tyrosine phosphatase-1B. J Med Chem 45(11):2213-221, 2002. PMID: 12014959.
- McGovern SL, Caselli E, Grigorieff N, Shoichet BK. A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening. J Med Chem 45(8):1712-722, 2002. PMID: 11931626.
- Irwin JJ, Lorber DM, McGovern SL, Wei B, Shoichet BK. Molecular docking and drug desin. J Comput Theor Nanosci 2, 2002. PMID: None.
- Beadle BM, McGovern SL, Patera A, Shoichet BK. Functional analyses of AmpC beta-lactamase through differential stability. Protein Sci 8(9):1816-824, 1999. PMID: 10493583.
- Ene C, Abi Faraj C, Beckham T, Weinberg JS, Andersen C, Haider A, Rao G, Ferguson S, Heimberger A, McCutcheon I, Prabhu S, Wang C, Ghia A, McGovern SL, Chung C, McAleer MF, Tom M, Perni S, Swanson T, Yeboa DN, Briere T, Lang F, Li J, Suki D, Fuller G, Huse J, Sawaya R, Kim B, Alvarez-Breckenridge C. Response of Treatment-Naive Brain Metastases to Stereotactic Radiosurgery. Springer Nature. PMID: None.
- Whitlock RS, Mehl SC, Chelius DC, Koshy JC, Mills JL, Ongkasuwan J, McGovern SL, FatihOkcue M, Naik-Mathuria B. Complex multidisciplinary resection of a malignant rhabdoid tumor of the neck & mediastinum in a pediatric patient. J of Ped Surg Case Reports 71. PMID: None.
Invited Articles
- McGovern SL, Mahajan A. Progress in radiotherapy for pediatric sarcomas. Curr Oncol Rep 14(4):320-26, 2012. PMID: 22532264.
- Shoichet BK, McGovern SL, Wei B, and Irwin JJ. Lead discovery using molecular docking. Current Opinion in Chemical Biology 6(4):439-446, 2002. e-Pub 2002. PMID: None.
Other Articles
- McGovern SL Atypical teratoid rhabdoid tumor (ATRT): Diagnosis, Treatment and Outlook. Cancerwise, 2023. PMID: None.
- Yarabarla V, Mylarapu A, Han TJ, McGovern SL, Raza SM, Beckham TH Intracranial meningiomas: An update of the 2021 World Health Organization classifications and review of management with a focus on radiation therapy. Front Oncol 22(13):1137849, 2023. PMID: 37675219.
- Grippin AJ, McGovern SL Proton therapy for pediatric diencephalic tumors. Front Oncol 13:1123082, 2023. PMID: 37213290.
- Serrallach BL, Tran BH, Bauer DF, Mohila CA, Adesina AM, McGovern SL, Lindsay HB, Huisman TA Pediatric spinal cord diffuse midline glioma, H3 K27-altered with intracranial and spinal leptomeningeal spread: A case report. Neuroradiol J 35(5):634-639, 2022. PMID: 34989626.
- Wilmas KM, Garner WB, Ballo MT, McGovern SL, MacFarlane DF The role of radiation therapy in the management of cutaneous malignancies. Part I: Diagnostic modalities and applications. J Am Acad Dermatol 85(3):539-548, 2021. PMID: 34116097.
- Zhang Z, Yang J, Ho A, Jiang W, Logan J, Wang X, Brown PD, McGovern SL, Guha-Thakurta N, Ferguson SD, Fave X, Zhang L, Mackin D, Court LE, Li J Correction to: A predictive model for distinguishing radiation necrosis from tumour progression after gamma knife radiosurgery based on radiomic features from MR images. Eur Radiol 28(8):3570-3571, 2018. PMID: 29541912.
- Guzman D, Edds E, Khatua S, McGovern SL, Robert R Obsessive-compulsive disorder after therapy for an optic pathway glioma. Adv Radiat Oncol 3(1):30-33, 2018. PMID: 29556577.
- Glitza IC, Guha-Thakurta N, D'Souza NM, Amaria RN, McGovern SL, Rao G, Li J Bevacizumab as an Effective Treatment for Radiation Necrosis after Radiotherapy for Melanoma Brain Metastases. Melanoma Res 27(6):580-584, 2017. PMID: 28817446.
- McGovern SL, Williams MD, Weber RS, Sabichi A, Chambers MS, Martin JW, Chao KS Three synchronous HPV-associated squamous cell carcinomas of Waldeyer's ring: case report and comparison with Slaughter's model of field cancerization. Head Neck 32(8):1118-124, 2010. PMID: 19572386.
Editorials
- McGovern SL. Impacts of HER2-overexpression and molecular targeting therapy on the efficacy of stereotactic radiosurgery for brain metastases from breast cancer. Breast Diseases: A Year Book Quarterly 25(2):157-158, 2014. PMID: None.
- McGovern SL. Factors influencing survival in patients with breast cancer and single or solitary brain metastasis. Breast Diseases: A Year Book Quarterly 23(1):48-49, 2012. PMID: None.
Abstracts
- De B, Ludmir EB, Maor MH, McGovern SL, McAleer MF, Grosshans DR, Woodhouse KD, Mahajan A, Paulino AC. Late Effects of Craniospinal Irradiation Using Electron Spinal Fields for Pediatric Patients. Int J Radiat Oncol Biol Phys 111(3S):e181, 2021. PMID: 34700857.
- Mak DY, Laperriere NJ, Ramaswamy V, Bouffet E, Murray JC, McNall-Knapp R, Bielamowicz K, Paulino AC, Zaky W, McGovern SL, Okcu F, Tabori U, Dirks PB, Taylor MD, Tsang DSC, Bavle A. Re-Evaluating Surgery and Re-Irradiation for Locally Recurrent Pediatric Ependymoma - a Multi-Institutional Study. Int J Radiat Oncol Biol Phys 111(3S):e174-e175, 2021. PMID: 34700843.
- McGovern SL, Johnson J, Kralik SK, Grosshans DR, McAleer MF, Zaky W, Baxter PA, Lin FY, Chintagumpala M, Paulino A. Pseudoprogression after proton therapy of pediatric spinal pilocytic astrocytoma and myxopapillary ependymoma. ISPNO 19th International Symposium on Pediatric Neuro-oncology Virtual Meeting, Nagano, Japan, 2020. PMID: None.
- Hanania AN, Chintagumpala M, Ludmir EB, Shah VS, McGovern SL, Grosshans DR, McAleer MF, Okcu MF, Baxter P, Su JM, Paulino AC. Clinical Outcomes following Proton Beam Therapy for Sporadic Optic Pathway Glioma. Int. J. Radiat. Oncol, 2020. PMID: None.
- Li J, Ludmir EB, Wang Y, Guha-Thakurta N, McAleer MF, Settle Jr SH, Yeboa DN, Ghia AJ, McGovern SL, Chung C, Woodhouse KD, Briere TM, Sullaway CM, Liu DD, Rao G, Chang EL, Mahajan A, Sulman EP, Brown PD, Wefel JS. Stereotactic Radiosurgery versus Whole-brain Radiation Therapy for Patients with 4-15 Brain Metastases: A Phase III Randomized Controlled Trial. Int. J. Radiat. Oncol, 2020. PMID: None.
- Bishop AJ, Livingston JA, Wages CA, Valdez I, Ning MS, Roth M, Gunn GB, McGovern SL. Adolescent and Young Adult Populations Face yet another Barrier to Care With Insurers. Int. J. Radiat. Oncol, 2020. PMID: None.
- Soliman M, Wang Y, Farooqi A, Bishop AJ, Yeboa DN, McGovern SL, McAleer MF, Briere TM, Campbell M, Tu SM, Ferguson S, Rao G, Nieto Y, Li J. Primary Management of Non-Seminomatous Germ Cell Brain Metastases with Stereotactic Radiosurgery: A Case Series. Int. J. Radiat. Oncol, 2020. PMID: None.
- Correia D, Giblin M, Bajaj B, Lawell MP, Gallotto S, Perry A, Weyman EA, Paulino AC, Grosshans DR, McAleer MF, McGovern SL, Friedmann A, Yeap BY, MacDonald S, Marcus KJ, Tarbell NJ, Yock TI. Health Outcomes and Quality of Life in a Multi-institutional Prospective Phase II Trial of Proton Radiotherapy for Pediatric Rhabdomyosarcoma. Int. J. Radiat. Oncol, 2020. PMID: None.
- McGovern SL, Lucari B, Jagannath K, Woodhouse KD, McAleer MF, Grosshans DR, Zaky W, Chintagumpala M, Paulino AC. Radiation Timing, Volume and Patterns of Failure in Infant Medulloblastoma. Int. J. Radiat. Oncol, 2020. PMID: None.
- Augustyn A, Ludmir EB, Patel RR, Maldonado A, Bishop AJ, Chung C, Ghia AJ, McAleer MF, McGovern SL, Woodhouse KD, Yeboa DN, Briere TM, Haydu LE, Ferguson S, Guha-Thakurta N, Glitza I, Li J. Concurrent Immunotherapy and Stereotactic Radiosurgery for Patients with Melanoma Brain Metastases is not Associated with Increased Risk of Brain Radionecrosis. Int. J. Radiat. Oncol, 2020. PMID: None.
- Noticewala SS, Ludmir EB, Bishop AJ, Chung C, Ghia AJ, Grosshans D, McGovern SL, Paulino AC, Wang C, Woodhouse KD, Yeboa DN, Prabhu SS, Weathers SP, Das P, Koong AC, McAleer MF, Li J. Radiation for Glioblastoma in the Era of Coronavirus Disease 2019 (COVID-19): Patient Selection and Hypofractionation to Maximize Benefit and Minimize Risk. Advances in Radiation Oncology, 2020. PMID: None.
- McGovern SL, Gallotto SL, Bajal BV, Lawell MP, Indelicato D, Paulino AC, Hartsell W, Laack N, Ermoian R, Vatner R, Perkins S, Mangona V, Hill-Kayser C, Wolden S, Kwok Y, Confer M, Wilkinson JB, Yock TI. Improving pediatric cancer patient follow up data collection through smartphone-based short health status check-ins using REDCap. Childhood Cancer Data Initiative Symposium, NCI, Washington DC, 2019. PMID: None.
- Holmes A, Ahem C, Berlind C, Smith B, Edwards T, Lindsay WD, McGovern SL. Building a pediatric oncology research database using point-of-care electronic data capture and automated data extraction software. Childhood Cancer Data Initiative Symposium, NCI, Washington DC, 2019. PMID: None.
- Nantavithya C, Yeboa DN, Liao K, McGovern SL, Grosshans DR, McAleer MF, Woodhouse KD, Khatua S. Secondary Malignant Neoplasms in Patients with Medulloblastoma. Int.J.Radiat. Oncol 102(3):e467-e468. e-Pub 2018. PMID: None.
- Konieczkowski DJ, Chen YLE, Berstein KD, Yeap BY, DiMaria MC, Jian W, Thomas N, McGovern SL. Prospective Phase II Study of Scanned Beam Proton Therapy for Spine Sarcomas. Int. J. Radiat. Oncol, 102(3):e325-e326. e-Pub 2018. PMID: None.
- Tran KT, McGovern SL, Allen PK, Mahajan A, McAleer MF, Li J, Ghia AJ, Sulman EP, Yeboa DN, DeMonte F, Raza SM, Grosshans DR, Bishop AJ. Similar Local Control Rates for Patients with Meningiomas Treated with Proton Therapy vs. IMRT. Int. J. Radiat. Oncol 102(3):e359. e-Pub 2018. PMID: None.
- Bagley A, Grosshans DR, Philip N, McAleer MF, McGovern SL, Foster J, Mahajan A, Paulino AC. Efficacy of Proton Therapy on Locoregional Control in Neuroblastoma. Int. J. Radiat. Onc 102(3):e472. e-Pub 2018. PMID: None.
- Bishop AJ, Tran KT, Allen PK, Mahajan A, McAleer MF, Li J, Ghia AJ, Sulman EP, Yeboa DN, DeMonte F, Raza SM, Grosshans DR, McGovern SL. Risk of Visual Toxicity Following Fractionated Proton vs Photon Radiation Therapy for Patients with Meningiomas. Int. J. Radiat. Oncol 102(3):e204. e-Pub 2018. PMID: None.
- Guha-Thakurta N, Bronk J, Mahajan A, Grosshans DR, McGovern SL. Imaging features of pseudoprogression in oligodendrogliomas. 118th American Roentgen Ray Society None(None):None, 2018. PMID: None.
- Konieczkowski DJ, Chen YL, Bernstein KD, Yeap BY, Dimaria MC, Jiang W, Thomas N, McGovern SL, Mullen JT, Schwab JH, Hornicek FJ, DeLaney TF. Prospective Phase II Study of Scanned beam Proton Therapy for Spine Chordomas and Chondrosarcomas. Chordoma Foundation International Research Conference, 2018. PMID: None.
- Guha-Thakurta N, Bronk JK, Mahajan A, Grosshans DR, McGovern SL. Pseudoprogression in Oligodendrogliomas. ENSR 2017, 2017. PMID: None.
- Wang X, Rao G, Li J, McAleer MF, McGovern SL, Ghia A, Sulman E, Brown P, Ferguson S, Heimberger A, Jr Lang F, McCutcheon I, Prabhu S, Sawaya R, Weinberg J, Ahmed S, Luo D, Mahajan A. Pattern of failure after resection and post-operative radiosurgery to the surgical cavity. ISRS 2017 None(None):None, 2017. PMID: None.
- Vera E, Scheurer M, Zhou R, Gilbert MR, Bondy M, Sulman E, Yuan Y, Liu Y, Wendland M, Brachman D, Bearden J, McGovern SL, Wilson S, Judy K, Robins HI, Hunter G, Crocker IR, Chao S, Kaluza V, Pugh S, Armstrong TS. Occurrence and implications of myelosuppression during concurrent therapy on rtog 0825. Neuro-Oncology 18(None):6-6, 2016. PMID: None.
- Bronk JK, Guha TN, Mahajan A, Grosshans DR, McGovern SL. Pseudoprogression after proton vs. photon therapy in patients with oligodendroglioma. Neuro-Oncology 18:179-179, 2016. PMID: None.
- Tann AWJ, McAleer MF, McGovern SL, Grosshans DR, Huh W, Paulino AC, Mahajan A. Clinical outcomes of pediatric patients with pelvic tumors treated with proton therapy. Int. J. Radiat. Oncol 96(2):E555-E555, 2016. PMID: None.
- Harrell LM, Paulino AC, Mahajan A, Grosshans DR, McGovern SL, McAleer MF, Okcu MF, Huh W. Clinical outcomes and toxicity following proton radiation therapy for head and neck rhabdomyosarcoma. Int. J. Radiat. Oncol 96(2):E549-550, 2016. PMID: None.
- McGovern SL. Outcomes of Gamma Knife radiosurgery in brain metastases from neuroendocrine tumors. Society for Neuro-Oncology, 2015. PMID: None.
- Grossberg A, Zhao Z, Walker G, Tsai J, Wang X, Jr LF, Phan J, Ghia A, McGovern SL, Mahajan A, Brown P, McAleer MF, Li J. Dose painting with Gamma Knife: Two techniques for delivering different doses to areas of recurrent or residual tumor after resection of brain metastases. None 5(6):390-397, 2015. e-Pub 2015. PMID: None.
- Grant S, Grosshans DR, Mahajan A, Bilton S, Garcia JA, Amin M, Chambers M, McGovern SL, McAleer MF, Morrison WH, Huh W, Kupferman ME. Protons versus conventional radiation therapy for pediatric salivary gland tumors:acute toxicity and dosimetric characteristics. Int. J. Radiat. Oncol 93(3):E311-E311, 2015. PMID: None.
- Mahajan A, McAleer MF, McGovern SL, Grosshans DR, Paulino AC. Pediatric radiation oncology practice patterns:after protons. Int. J. Radiat. Oncol 93(3):E506-E506, 2015. PMID: None.
- Lassen-Ramshad Y, McGovern SL, Seiersen K, Mahajan A. Sparing of kidney with proton radiotherapy for flank irradiation in bilateral nephroblastoma. Annual Meeting of PROS None(None):None, 2015. PMID: None.
- Maher MM, Sandberg DI, Kannan G, McGovern SL, Ketonen L, Khatua S, Zaky W. MS-17, Primary Leptomeningeal Primitive Neuroectodermal Tumor. Neuro-Oncology 130(None):None, 2014. PMID: None.
- McGovern SL, Grosshans DR, McAleer MF, Chintagumpala M, Khatua S, Vats T, Mahajan A. Preliminary results from the use of proton beam radiation in at/rt. Neuro-Oncology 14(None):134-134, 2012. PMID: None.
Book Chapters
- Tang C, Farooqi A, McGovern SL. Pediatrics. In: Pocket Radiation Oncology, 2e. None. Wolters Kluwer Health Learning, Research & Practice, 2024.
- Garner, WB, McGovern, SL, Ballo, MT. Radiation oncology in skin cancer treatment, 311-326, 2021.
- McGovern SL. ATRT and ETMR. In: Radiation oncology for brain tumors in children. None. Springer International Publishing AG, 147-162, 2018.
- McGovern SL, McAleer MF, Mahajan A. Pediatric Radiotherapy. In: Radioterapia Contemporanea. None. Atheneu, 2017.
- Hristov B, Lin SH, Christoduouleas JP, McGovern SL. Radiation Oncology. In: A Question Based Review, 2nd Edition. None. Wolters Kluer, None, 2015.
- McGovern SL, Ballo MT. Radiation Oncology in Skin Cancer Treatment. In: A Practical Approach to Skin Cancer Management. None. Springer, 259 – 272, 2010.
- Hristov B, Lin SH, Christodouleas JP, McGovern SL. Radiation Oncology. In: A Question Based Review, 3rd Edition. None. None, None, 2010.
- McGovern SL. Promiscuous ligands. In: Comprehensive Medicinal Chemistry II, Vol. 2, Strategy and Drug Research. None. Elsevier Press, 737 – 751, 2007.
- McGovern SL. Experimental identification of promiscuous, aggregate-forming screening hits. In: Virtual Screening in Drug Discovery. None. CRC Press, Inc, 107 – 124, 2005.
Letters to the Editor
- Amsbaugh MJ, Mahajan A, Thall PF, McAleer MF, Paulino AC, Grosshans D, Khatua S, Ketonen L, Fontanilla H, McGovern SL. In Reply to Krishnatry and Manjali. Int. J Radiat Oncol Biol Phys 104: 468-469, 2019.
- Ludmir EB, Mahajan A, Ahern V, Ajithkumar T, Alapetite C, Bernier-Chastagner V, Bindra RS, Bishop AJ, Bolle S, Brown PD, Carrie C, Chalmers AJ, Chang EL, Chung C, Dieckmann K, Esjashvili N, Gandola L, Ghia AJ, Gondi V, Grosshans DR, Harrabi SB, Horan G, Indelicato DJ, Jalali R, Janssens GO, Krause M, Laack NN, Laperriere N, Laprie A, Li J, Marcus KJ, McGovern SL, Merchant TE, Merrell KW, Padovani L, Parkes J, Paulino AC, Schwarz R, Shih HA, Souhami L, Sulman EP, Taylor RE, Thorp N, Timmermann B, Wheeler G, Wolden SL, Woodhouse KD, Yeboa DN, Yock TI, Kortmann RD, McAleer MF. Assembling the brain trust: the multidisciplinary imperative in neuro-oncology. Nat Rev Clin Oncol.
- Welsh JW, McGovern SL, Wefel JS, Komaki R, Brown PD, Soh HE. Reply to V.R. Bhatt, et al. M.C. Chamberlin. Journal of Clinical Oncology 31: 3165-3166, 2013.
Grant & Contract Support
| Title: | Pediatric, Adolescent, and Young Adult Patients With WHO Grade 4 Gliomas: A Multi-Institutional Study Evaluating Outcomes and Patterns of Failure |
| Funding Source: | Dr. Susan McGovern/Dr. Joshua Palmer, matched by the Department of Radiation Oncology at Ohio State University |
| Role: | Principal Investigator/Scientific Advisor |
| Title: | Pilot trial dose-volume constraints for re-irradiation of recurrent brain tumor |
| Funding Source: | Dr. Marnie Rose Foundation |
| Role: | PI |
| Title: | Improving the clinical effectiveness and understanding of the biophysical basis - Project 2: Exploratory Clinical Trials to Exploit the Physical and Biophysical Properties of Protons Including Reduction in Dose Bath with Protons |
| Funding Source: | NIH/NCI |
| Role: | Collaborator |
| Title: | NLM |
| Funding Source: | NLM |
| Role: | Trainee |
| Title: | A prospective RCT of exercise to ameliorate cognitive deficits from radiotherapy in adolescents and young adults (AYAs) with brain tumors |
| Funding Source: | ROSI HSR Seed Award |
| Role: | PI |
| Title: | Pilot Study of Strata XRT for the Prevention of Radiation Dermatitis St.Baldricks Foundation |
| Funding Source: | NIH/NCI |
| Role: | PI |
| Title: | Strata XRT use in Pediatric Proton CSI Radiation Therapy "A Pilot Study" |
| Funding Source: | NIH/NCI |
| Role: | PI |
Patient Reviews
CV information above last modified December 20, 2024