Theresa M. Hofstede, BSc, DDS, FACP
Department of Head and Neck Surgery, Division of Surgery
About Dr. Hofstede
Dr. Theresa Hofstede is a Professor in the Oral Oncology and Maxillofacial Prosthodontics section at The University of Texas MD Anderson Cancer Center, Houston, Texas. She works very closely with my colleagues in Head and Neck Surgery, Plastic and Reconstructive Surgery, and Radiation Oncology. She sees well over 1000 head and neck cancer patients annually, and have extensive experience evaluating and managing the oral morbidities of the head and neck cancer patient, before, during and after treatment. She serve as the Program Director of the oldest US accredited Advanced Education Program in Oral Oncology and Maxillofacial Prosthodontics and manage schedules, curriculum, and lead operations of the program. She is an active collaborator in multiple research projects within the Department of Head and Neck Surgery.
Dr. Hofstede have also driven the effort to increase implant placement and rehabilitation in the oncology patient. Her academic foundation is steeped in historical principles, quality in education, diverse cutting edge technology, and nurturing our next generation of leaders in oral oncology and maxillofacial prosthodontics. A true passion!
Present Title & Affiliation
Primary Appointment
Professor, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, HOUSTON, TX
Program Director, Advanced Education Program in Maxillofacial Prosthodontics and Oral Oncology, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Associate Medical Director, Section of Oral Oncology and Maxillofacial Prosthodontics, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Director, Maxillofacial Prosthodontic Dental Laboratory, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Program Director, Oncologic-Based Maxillofacial Implant Fellowship Program, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Director, The Oral Oncology 3D Printing Service, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
Radiation-induced xerostomia
Education & Training
Degree-Granting Education
| 1991 | University of Western Ontario, London, CAN, DDS, General Dentistry |
| 1987 | University of Toronto, Toronto, CAN, BSc, Chemistry |
Postgraduate Training
| 2006-2007 | Clinical Fellowship, Maxillofacial and Dental Oncology Fellowship, The University of Texas MD Anderson Cancer Center, Houston, TX |
| 1996-1999 | Clinical Residency, Prosthodontics, University of Rochester Eastman Dental Center, Rochester, NY |
| 1991-1992 | Clinical Residency, General Practice, St. Joseph's Hospital, London |
Board Certifications
| 2008 | American Board of Prosthodontics |
| 2002 | North East Regional Boards |
| 2000 | National Dental Boards, Part I and II |
| 1999 | Canadian Prosthodontics Board |
| 1991 | National Dental Examining Board of Canada |
Experience & Service
Academic Appointments
Associate Professor, Department of Head and Neck Surgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2013 - 2020
Assistant Professor, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2007 - 2013
Assistant Professor, Division of Prosthodontics, University of Rochester Eastman Dental Center, Rochester, NY, 2003 - 2006
Assistant Professor, Nova Southeastern University, Fort Lauderdale, FL, 2000 - 2001
Instructor, University of Western Ontario, London, 1999 - 2000
Administrative Appointments/Responsibilities
Chairman, Oral Oncology Symposium 2022, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2022 - 2022
Member, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2020 - Present
Committee Panel Member, American Dental Association - Cancer Research, Chicago, IL, 2019 - Present
Appeal Board Committee Member, Commission on Dental Accreditation Appeal Board, Chicago, IL, 2018 - Present
Chairman, Oral Oncology Symposium 2017, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - 2017
Chairman, Oral Oncology Symposium: Current Trends in Oncologic Dentistry and Maxillofacial Prosthetics, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2014 - 2014
Chairman, Oral Oncology Symposium: Current Trends in Oncologic Dentistry and Maxillofacial Prosthetics, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2011 - 2011
Program Chair, Dental Oncology Core Curriculum Series (MODO-1501), Section of Oral Oncology and Maxillofacial Prosthodontics, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - 2015
Program Chair, Dental Oncology Didactic Lecture Series (MODO-1503), Section of Oral Oncology and Maxillofacial Prosthodontics, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - 2015
Other Appointments/Responsibilities
Dentist, Private Practice, Rochester, NY, 2002 - 2006
Dentist, Private practice, Ontario, 1999 - 2000
Dentist, Private Practice, Ontario, 1991 - 1996
Institutional Committee Activities
Member (Alternate), Credentials Committee of the Medical Staff (CCMS), 2020 - 2023
Member, Faculty Leadership Academy UT MD Anderson Cancer Center, 2016 - 2017
Officer, Electronic Health Record (EHR) Provider, 2015 - Present
Super User, Electronic Health Record (EHR) Provider, 2015 - Present
Alternate, OR Advisory Sub-Committee, 2014 - 2022
Associate Member, GME Committee, 2011 - Present
Member, GME Curriculum Subcommittee, 2011 - Present
Member, Faculty Search Committee, Dept. of Head & Neck Surgery, Section of Oncologic Dentistry and Prosthodontics, Chairman: Dr. Mark S. Chambers, 2010 - Present
Consultantships
Consultant, American Dental Association (ADA) Council on Scientific Affairs (CSA), Cook County, Illinois, 2019 - 2021
Honors & Awards
| 2022 | Top 1% Provider: Fiscal Year 2022, Clinical and Group Consumer Assessment of Health Providers and Systems (CGCAHPS) |
| 2017 | Distinguished Educator of the Year Award, Section of Oral Oncology, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center |
| 2014 | Schulich Medicine & Dentistry Young Alumni Award of Distinction (Dentistry 2014)), Western University, London, Ontario, Canada |
| 2010 | Judson C. Hickey Scientific Writing Award in the Clinical Category, Award bestowed at the Annual Session of the American Academy of Maxillofacial Prosthetics, 2011, The Journal of Prosthetic Dentistry |
| 2000 | Tylman Research Second Place Award |
| 2000 | John J. Sharry Research Competition Third Place Award |
| 1998 | American Academy of Fixed Prosthodontics |
| 1991 | London and District Dental Society Award, London and District Dental Society |
| 1991 | Toronto Crown and Bridge Award |
| 1989 | MRC Research Scholarship |
| 1988 | Graduation Prize in Physical Sciences, University of Toronto Scarborough College |
| 1986 | Division of Physical Sciences Award, University of Toronto |
| 1986 | Toronto Section Book Prize, Chemical Institute of Canada |
| 1986 | Canadian Society for Chemistry Silver Metal, CIC and the Canadian Society for Chemistry |
| 1986 | NSERC Research Scholarship |
| 1984 | Lloyd Richardson Memorial Scholarship, Dunnville Secondary School |
| 1984 | Ontario Scholar, Provincial Government of Ontario |
| 1984 | Hettie Helier Memorial Scholarship, Dunnville Secondary School |
| 1984 | University of Toronto Admission Scholarship, University of Toronto |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Asfar MM, Won AM. Skoracki R, Hofstede TM. Maxillary Reconstruction of an Adolescent Patient with Mucoepidermoid Carcinoma: A Clinical Report. Texas Dental Journal 138(6):382 - 395, 2021.
- Alqarni H, Montgomery P, Aponte-Wesson R, Won AM, Hofstede TM, Chambers MS. Combined Rehabilitation of a Low Lip Defect After Resection of the Floor of the Mouth: A Clinical Report. J Prosthet Dent 21(S0022-3913):00150-5. e-Pub 2021. PMID: 33867164.
- MD Anderson Head and Neck Surgery Treatment Guidelines Consortium, Consortium members, Maniakas A, Jozaghi Y, Zafereo ME, Sturgis EM, Su SY, Gillenwater AM, Gidley PW, Lewis CM, Diaz E, Goepfert RP, Kupferman ME, Gross ND, Hessel AC, Pytynia KB, Nader ME, Wang JR, Lango MN, Kiong KL, Guo T, Zhao X, Yao CMKL, Appelbaum E, Alpard J, Garcia JA, Terry S, Flynn JE, Bauer S, Fournier D, Burgess CG, Wideman C, Johnston M, You C, De Luna R, Joseph L, Diersing J, Prescott K, Heiberger K, Mugartegui L, Rodriguez J, Zendehdel S, Sellers J, Friddell RA, Thomas A, Khanjae SJ, Schwarzlose KB, Chambers MS, Hofstede TM, Cardoso RC, Wesson RA, Won A, Otun AO, Gombos DS, Al-Zubidi N, Hutcheson KA, Gunn GB, Rosenthal DI, Gillison ML, Ferrarotto R, Weber RS, Hanna EY, Myers JN, Lai SY. Treatment Guidelines Consortium: Head and Neck Surgical Oncology in the Time of a Pandemic - Subsite-specific triage guidelines during the COVID19 pandemic. Head Neck 42(6):1194 - 1201, 2020. e-Pub 2020. PMID: 32342541.
- Kamal M, Barrow MP, Lewin JS, Estrella A, Gunn GB, Shi Q, Hofstede TM, Rosenthal DI, Fuller CD, Hutcheson KA, MD Anderson Head and Neck Cancer Symptom Working Group. Modeling symptom drivers of oral intake in long-term head and neck cancer survivors. Support Care Cancer 27(4):1405-1415, 2019. e-Pub 2018. PMID: 30218187.
- Chi WJ, Hanasono MM, Hofstede TM, Aponte-Wesson RA. Prosthodontic treatment of a patient with Ewing sarcoma of left maxillary sinus: A Clinical Report. J Prosthet Dent 121(121):698-702, 2019. e-Pub 2018. PMID: 30503146.
- Mohamed A, Song J, Hutcheson K, Murri M, Garg N, Hobbs B, Gunn B, Sandulache V, Beadle B, Phan J, Morrison W, Frank S, Blanchard P, Garden A, El-Halawani H, Kamal M, Chambers M, Lewin JS, Ferrarotto R, Zhu R, Zhang C, Hofstede TM, Cardoso RC, Gillenwater AM, Sturgis EM, Weber RS, Rosenthal DI, Fuller CD, Lai SY. Dose-volume correlates of mandibular osteoradionecrosis in oropharynx cancer patients receiving intensity-modulated radiotherapy: Results from a case-matched comparison. Radiother Oncol 124((2)):232-239, 2017. e-Pub 2017. PMID: 28733053.
- Hofstede TM, Jacob RF, Montgomery P, Wesley P. Surgical preparation of nasal defects to enhance the implant-retained facial prostheses: A case report. Head Neck 39(1):E4 - E11, 2017. e-Pub 2016. PMID: 27618726.
- Wong AT, Lai SY, Gunn GB, Beadle BM, Fuller CD, Barrow MP, Hofstede TM , Chambers MS, Sturgis EM, Mohamed ASR, Lewin JS, Hutcheson KA. Symptom Burden and Dysphagia Associated with Osteoradionecrosis in Long-Term Oropharynx Cancer Survivors: A Cohort Analysis. Oral Oncology 66:75-80, 2017. e-Pub 2017.
- Won AM, Hofstede TM, Cardoso RC, Otun AO, Chambers MS. Sunitinib and Zoledronic Acid Combination Therapy for Metastatic Renal Cell Carcinoma: Alarming for Osteonecrosis of the Jaw. Kidney Cancer Journal 15(2):49-51, 2017.
- Sandulache VC, Hobbs BP, Mohamed ASR, Frank SJ, Song J, Ding, Y, Ger R, Court LE, Kalpathy-Cramer J, Hazle JD, Wang J, Awan MJ, Rosenthal DI, Garden AS, Gunn GB, Colen RR, Elshafeey N, Elabanan M, Hutcheson KA, Lewin JS, Chambers MS, Hofstede TM, Weber RS, Lai SY, Fuller CD. Dynamic contrast-enhanced MRI detects acute radiotherapy-induced alterations in mandibular microvasculature: prospective assessment of imaging biomarkers of normal tissue injury. Joint Head and Neck Radiotherapy-MRI Development Cooperative. Scientific Reports 94(4):924, 2016. e-Pub 2016. PMID: 27499209.
- Tucker JR, Xu L, Sturgis EM, Mohamed AS, Hofstede TM, Chambers MS, Lai SY, Fuller CD, Beadle B, Gunn GB, Hutcheson KA. Osteoradionecrosis in Patients with Salivary Gland malignancies. Oral Oncol 57(57):1-5, 2016. e-Pub 2016. PMID: 27208837.
- Ch'ng S, Skoracki RJ, Selber JC, Yu P, Martin JW, Hofstede TM, Chambers MS, Liu J, Hanasono MM. Osseointegrated Implant Based Dental Rehabilitation in Head and Neck Reconstruction Patients. Head Neck 38(Suppl. 1):E321-27, 2016. e-Pub 2015. PMID: 25546139.
- Cardoso RC, Gerngross PJ, Hofstede TM, Weber DM, Chambers MS. The Multiple Oral Presentations of Multiple Myeloma. Support Care Cancer 22(1):259 - 67, 2014. e-Pub 2013. PMID: 24048519.
- Tsai CJ, Hofstede TM, Sturgis EM, Garden AS, Lindberg ME, Wei Q, Tucker SL, Dong L. Osteoradionecrosis and Radiation Dose to the Mandible in Patients With Oropharyngeal Cancer. Int J Radiat Oncol Biol Phys 85(2):415-20, 2013. e-Pub 2012. PMID: 22795804.
- Nguyen CT, Hofstede TM. Prosthodontic Treatment and Medical Considerations for a Patient with Turner Syndrome: A Clinical Report. J Prosthodont(7):552-555. e-Pub 2012. PMID: 22672559.
- Kumar VA, Hofstede TM, Ginsberg LE. CT Imaging Features of Obturator Prostheses in Patients following Palectomy or Maxillectomy. AJNR Am J Neuroradiol 32(10):1926-9, 2011. e-Pub 2011. PMID: 21799037.
- Hofstede TM, Jacob RF. Diagnostic considerations and prosthetic rehabilitation of a cocaine-induced midline destructive lesion: A clinical report. J Prosthet Dent 103:1-5, 2010. e-Pub 2010. PMID: 20105673.
- Bidra AS, Hofstede TM, Skoracki RJ, Jacob RF. Maxillofacial rehabilitation of a 7-year old boy with osteosarcoma of the mandible using a free fibula flap and implant supported prosthesis: a clinical report. J Prosthet Dent 102(6):348-353, 2009. e-Pub 2009. PMID: 19961992.
- Hofstede TM, Ercoli C. An indirect technique for fabrication of a post and core wax pattern. J Prosthet Dent 87(3):341-342, 2002. PMID: 11941366.
- Hofstede TM, Ercoli C, Graser GN, Tallents RH, Moss ME, Zero DT. Influence of metal surface finishing on porcelain porosity and beam failure loads at the metal-ceramic interface. J Prosthet Dent 84(3):309-17, 2000. PMID: 11005904.
- Hebel K, Gajjar R, Hofstede TM. Single-Tooth Replacement: Bridge vs. implant-supported restoration. J Can Dent Assoc 66(8):435-438, 2000. PMID: 11040527.
- Hofstede TM, Ercoli C, Hagan ME. Alternative complete-arch cement-retained implant-supported fixed partial denture. J Prosthet Dent 82(1):94-9, 1999. PMID: 10384169.
- Ricci J, Koetzle T, Bautista M, Hofstede TM, Morris R, Sawyer J.. Single-crystal X-ray and neutron diffraction studies of an .eta. 2- Dihydrogen transition-metal complex. J Am Chem Soc 111:8823-8827, 1989.
- Won A, Hofstede TM, Chambers MS, Aponte Wesson R. Destruction of the hard palate and oral nasal communication caused by pervious treatment with sunitinib and zoledronic acid: Case Report. J. Med Case Rep.
- Won AM, Hofstede TM, Cardoso RC, Otun AO, Chambers MS. Osteonecrosis of the jaw from Tyrosine kinase inhibitors therapy: Two case reports. JADA.
Invited Articles
- Tan KM, Hofstede TM, Chambers MS. Mental Neuropathy in an Oncologic Setting: A Review of Nine Cases. Greater Houston Dental Society 83(1):17-22, 2011. e-Pub 2011.
Manuals, Teaching Aids, Other Teaching Publications
- Hofstede TM. Taking the Bite out of Oral Complications. Coping® Magazine: Franklin, TN, 2010.
- Hofstede TM. Daily Fluoride Therapy Index Card, Patient Teaching Aid, 2010.
- Hofstede TM. Problems Associated with Radiation Therapy to the Head and Neck. MD Anderson, 2010.
- Hofstede TM, Chambers MS. Oral care and Cancer therapy. TLC GrapeVine Publication: Houston, TX, 2009.
Other Articles
- Hofstede TM Dental Implants: A Cancer Perspective, July 2016. ProFILES 10(1), 2016.
- Hofstede, TM Dental Hygiene and Care Before, During and After Cancer Treatment. OncoLog (MD Anderson' Report to Physicians) 60(6), 2015.
- Jorewicz L, Hofstede TM Managing Dental Complications in Patients with Head and Neck Cancer. OncoLog (MD Anderson's Report to Physicians) 58(11/12), 2013.
- Hanasono MM, Hofstede TM Craniofacial Reconstruction Following Oncologic Resection. Neurosurg Clin N Am 24(1):111-124, 2013. PMID: 23174362.
Abstracts
- Tucker JR, Xu L, Sturgis EM, Mohamed ASR, Hofstede TM, Chambers MS, Lai SY, Fuller CD, Beadle BM, Gunn GB, Hutcheson KA. Osteoradionecrosis in Salivary Gland Malignancies. Presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium, February 18-20, 2016 Scottsdale, AZ, 2016.
- Tucker Jr, Xu L, Sturgis EM, Hofstede TM, Chambers MS, Gunn GB, Fuller CD, Mohamed ASR, Lai S, Hutcheson KA. Osteoradionecrosis After Radiotherapy for Salivary Gland Malignances. Presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium, 2015 American Society for Radiation Oncology 57th Annual Meeting, San Antonio, TX October 2015, 2015.
- Tsai CJ, Hofstede TM, Sturgis EM, Garden AS, Lindberg ME, Wei Q, Tucker SL, Dong L. Osteoradionecrosis and Radiation Dose to the Mandible in Patients with Oropharyngeal Cancer. Int J Radiat Oncol Biol Phys. e-Pub 2012. PMID: 22795804.
- Kumar VA, Ginsberg LE, Hofstede T. CT imaging appearance of obturators prostheses in patients status post partial palatectomy. American Society of Head and Neck Radiology 43rd Annual Meeting Program Proceedings Book, 2009.
- J Dent Res. Bond strengths of luting resins to sandblasted base metal alloys. J Dent Res 70:388, 1991.
- McConnell RJ, Hofstede TM, Gratton DR, Quinn F.. Bond strengths of Panavia EX to treated Metal surfaces. J Dent Res 69:172, 1990.
Book Chapters
- Montgomery PC, Hofstede TM, Chambers MS. Auricular Prosthetic Rehabilitation. In: Temporal Bone Cancer. Springer, Nature, 355 - 362, 2018.
- Cardoso RC, Hofstede TM, Martin JW, Garden AS, Aponte-Wesson RA, Montgomery P, Chambers MS. Chapter 29: Oral and Maxillofacial Rehabilitation of Patients with Head and Neck Cancer. In: Cancer of the Head and Neck. Wolters Kluwer: Philadelphia, 2016.
- Hofstede TM, Montgomery PC, Cardoso RC. Chapter 15: Dental and Facial Prosthetic Rehabilitation. In: Reconstructive Plastic Surgery of the Head and Neck: Current Techniques and Flap Atlas. Thieme Publishers INC: New York, 203-219, 2016.
- Aponte-Wesson R, Hofstede TM, Cardoso RC, Montgomery P, Won A, Martin JW, Chambers M. Chapter 54: Oral Oncology. In: Head and Neck Cancer: Multimodality Management 2nd Edition. Springer Science + Business Media: Philadelphia, PA, 2015.
- Hofstede TM, Martin JW, Lemon JC, Chambers MS. Chapter 9: Dental Oncology and Maxillofacial Prosthetics. In: Head and Neck Cancer: A Multidisciplinary Approach. 4th. Lippincott Williams & Wilkins: Philadelphia, PA, 185-202, 2014.
- Hofstede TM, Montgomery PC, Jacob RF, Wesley PJ, Martin JW, Chambers MS. Chapter 39: Prosthetic Rehabilitation. In: Cutaneous Malignancy of the Head and Neck: A Multidisciplinary Approach. Plural Publishing Inc: San Diego, CA, 587-599, 2011.
- Hofstede, TM, Jacob RF, Montgomery, PC, Wesley, PJ, Martin, JW, Chambers MS. Chapter 9: Prosthetic Rehabilitation of Patients Undergoing Skull Base Surgery. In: Comprehensive Management of Skull Base Tumors, 2008.
- Hofstede TM, Toth BB, Martin JW, Jacob RF, Montgomery PC, Wesley PJ, Chambers MS. Chapter 22: Dental and Prosthetic Considerations. In: M.D. Anderson Cancer Care Series, Head and Neck Cancer Volume, 2008.
- Aponte-Wesson R, Hofstede TM, Cardoso RC, Montgomery R, Won AM, Martin JW, Chambers MS. Head and Neck Cancer: Multimodality Management. In: Oral Oncology. 2nd. Springer: New York.
Patient Reviews
CV information above last modified June 05, 2024