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Uwe Titt, Ph.D.

Present Title & Affiliation

Primary Appointment

Associate Professor, Department of Radiation Physics - Patient Care, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Office Address

The University of Texas MD Anderson Cancer Center
1515 Holcombe Blvd.
Unit Number: Unit 94
Houston, TX 77030
Room Number: Y2.5336
Phone: (713) 563-2558
Fax: (713) 563-2479

Education & Training

Degree-Granting Education

1994 Johann Wolfgang Goethe Universitat, Frankfurt, Germany, Diploma examination, Nuclear Physics
1994 Johann Wolfgang Goethe Universität, Frankfurt, Germany, PHD, Nuclear Physics
1991 Johann Wolfgang Goethe Universitat, Frankfurt, Germany, Pre-examination Diploma, Pre-examination

Selected Publications

Peer-Reviewed Original Research Articles

1. Kry SF, Salehpour M, Titt U, White RA, Stovall M, Followill D. Monte Carlo study shows no significant difference in second cancer risk between 6- and 18-MV intensity-modulated radiation therapy. Radiother Oncol 91(1):132-7, 4/2009. e-Pub 1/2009. PMID: 19147246.
2. Vassiliev ON, Kry SF, Chang JY, Balter PA, Titt U, Mohan R. Stereotactic radiotherapy for lung cancer using a flattening filter free Clinac. J Appl Clin Med Phys 10(1):2880, 2009. PMID: 19223837.
3. Sawakuchi GO, Titt U, Mirkovic D, Mohan R. Density heterogeneities and the influence of multiple Coulomb and nuclear scatterings on the Bragg peak distal edge of proton therapy beams. Phys Med Biol 53(17):4605-19, 9/2008. e-Pub 8/2008. PMID: 18678928.
4. Vassiliev ON, Wareing TA, Davis IM, McGhee J, Barnett D, Horton JL, Gifford K, Failla G, Titt U, Mourtada F. Feasibility of a multigroup deterministic solution method for three-dimensional radiotherapy dose calculations. Int J Radiat Oncol Biol Phys 72(1):220-7, 9/2008. PMCID: PMC2597668.
5. Titt U, Sahoo N, Ding X, Zheng Y, Newhauser WD, Zhu XR, Polf JC, Gillin MT, Mohan R. Assessment of the accuracy of an MCNPX-based Monte Carlo simulation model for predicting three-dimensional absorbed dose distributions. Phys Med Biol 53(16):4455-70, 8/21/2008. e-Pub 7/31/2008. PMID: 18670050.
6. Kry SF, Howell RM, Titt U, Salehpour M, Mohan R, Vassiliev ON. Energy spectra, sources, and shielding considerations for neutrons generated by a flattening filter-free Clinac. Med Phys 35(5):1906-11, 5/2008. PMID: 18561666.
7. Taddei PJ, Fontenot JD, Zheng Y, Mirkovic D, Lee AK, Titt U, Newhauser WD. Reducing stray radiation dose to patients receiving passively scattered proton radiotherapy for prostate cancer. Phys Med Biol 53(8):2131-47, 4/2008. e-Pub 3/2008. PMID: 18369278.
8. Koch N, Newhauser WD, Titt U, Gombos D, Coombes K, Starkschall G. Monte Carlo calculations and measurements of absorbed dose per monitor unit for the treatment of uveal melanoma with proton therapy. Phys Med Biol 53(6):1581-94, 3/2008. e-Pub 2/2008. PMID: 18367789.
9. Titt U, Zheng Y, Vassiliev ON, Newhauser WD. Monte Carlo investigation of collimator scatter of proton-therapy beams produced using the passive scattering method. Phys Med Biol 53(2):487-504, 1/2008. e-Pub 12/2007. PMID: 18185001.
10. Polf JC, Harvey MC, Titt U, Newhauser WD, Smith AR. Initial beam size study for passive scatter proton therapy. I. Monte Carlo verification. Med Phys 34(11):4213-8, 11/2007. PMID: 18072485.
11. Kry SF, Titt U, Followill D, Pönisch F, Vassiliev ON, White RA, Stovall M, Salehpour M. A Monte Carlo model for out-of-field dose calculation from high-energy photon therapy. Med Phys 34(9):3489-99, 9/2007. PMID: 17926952.
12. Fontenot JD, Newhauser WD, Bloch C, White RA, Titt U, Starkschall G. Determination of output factors for small proton therapy fields. Med Phys 34(2):489-498, 2007. PMID: 17388166.
13. Newhauser WD, Fontenot JD, Zheng U, Polf JC, Titt U, Koch N, Zhang X, Mohan R. Monte Carlo simulations for configuring and testing an analytical proton dose-calculation algorithm. Phys Med Biol 52(15):4569-4584, 2007. e-Pub 7/10/2007. PMID: 17634651.
14. Vassiliev ON, Titt U, Kry SF, Mohan R, Gillin MT. Radiation safety survey on a flattening filter-free medical accelerator. Radiat Prot Dosimetry 124(2):187-90, 2007. e-Pub 8/6/2007. PMID: 17681966.
15. Kry SF, Titt U, Ponisch F, Vassiliev ON, Salehpour M, Gillin MT, Mohan R. Reduced neutron production through use of a flattening-filter-free accelerator. Int J Radiat Oncol Biol Phys 68(4)(4):1260-1264, 2007. PMID: 17637397.
16. Vassiliev ON, Kry SF, Kuban DA, Salehpour M, Mohan R, Titt U. Treatment-Planning Study of Prostate Cancer Intensity-Modulated Radiotherapy with a Varian Clinic Operated without a Flattening Filter. Int J Radiat Oncol Biol Phys 68(5)(5):1567-1571, 2007. e-Pub 6/4/2007. PMID: 17544596.
17. Titt U, Vassiliev ON, Ponisch F, Dong L, Liu H, Mohan R. A flattening filter free photon treatment concept evaluation with Monte Carlo. Med Phys 33(6):1595-1602, 6/2006. PMID: 16872067.
18. Vassiliev ON, Titt U, Kry SF, Ponisch F, Gillin MT, Mohan R. Monte Carlo study of photon fields from a flattening filter-free clinical accelerator. Med Phys 33(4):820-827, 4/2006. PMID: 16696457.
19. Kry SF, Titt U, Ponisch F, Followill D, Vassiliev ON, White RA, Mohan R, Salehpour M. A Monte Carlo model for calculating out-of-field dose from a varian 6 MV beam. Med Phys 33(11):4405-4413, 2006. PMID: 17153419.
20. Vassiliev ON, Titt U, Ponisch F, Kry SF, Mohan R, Gillin MT. Dosimetric properties of photon beams from a flattening filter free clinical accelerator. Phys Med Biol 51(7):1907-1917, 2006. e-Pub 3/21/2006. PMID: 16552113.
21. Ponisch F, Titt U, Kry SF, Vassiliev ON, Mohan R. MCNPX simulation of a multileaf collimator. Med Phys 33(2):402-404, 2006. PMID: 16532947.
22. Titt U, Vassiliev ON, Ponisch F, Kry SF, Mohan R. Monte Carlo study of backscatter in a flattening filter free clinical accelerator. Med Phys 33(9):3270-3273, 2006. PMID: 17022221.
23. Ponisch F, Titt U, Vassiliev ON, Kry SF, Mohan R. Properties of unflattened photon beams shaped by a multileaf collimator. Med Phys 33(6):1738-46, 2006. PMID: 16872081.
24. Newhauser WD, Ding X, Giragosian D, Nill S, Titt U. A Neutron radiation area monitoring system for proton therapy facilities. Radiat Prot Dosimetry 115(1-4):149-153, 2005. PMID: 16381703.
25. Newhauser W, Koch N, Hummel S, Ziegler M, Titt U. Monte Carlo simulations of a nozzle for the treatment of ocular tumours with high-energy proton beams. Phys Med Biol 50(22):5229-5249, 2005. e-Pub 10/24/2005. PMID: 16264250.
26. Titt U, Newhauser WD. Neutron shielding calculations in a proton therapy facility based on Monte Carlo simulations and analytical models: criterion for selecting the method of choice. Radiat Prot Dosimetry 115(1-4):144-148, 2005. PMID: 16381702.
27. Polf JC, Newhauser WD, Titt U. Patient neutron dose equivalent exposures outside of the proton therapy treatment field. Radiat Prot Dosimetry 115(1-4):154-158, 2005. PMID: 16381704.
28. Bues M, Newhauser WD, Titt U, Smith AR. Therapeutic step and shoot proton beam spot-scanning with a multi-leaf collimator: a Monte Carlo study. Radiat Prot Dosimetry 115(1-4):164-169, 2005. PMID: 16381706.
29. Fontenot JD, Newhauser WD, Titt U. Design tools for proton therapy nozzles based on the double-scattering foil technique. Radiat Prot Dosimetry 31(1-4 Pt 2):1723, 2004. PMID: 16604629.
30. Titt U, Dangendorf V, Grobwendt V, Schuhmacher H. Development and Application of an Optical TPC for Charged Particle Track Structure Imaging in Microdosimetry. Nuclear Instruments and Methods A477:536-539, 2002.
31. Dangendorf V, Schuhmacher H, Titt U, Tittelmeier K. Imaging of microscopic features of charged particle tracks in a low-pressure gas. Radiat Prot Dosimetry 99:353-354, 2002. PMID: 12194322.
32. Yan X, Newhauser WD, Titt U, Koehler AM. Measurement of neutron dose equivalent to proton therapy patients outside of the proton radiation field. Nuclear Instruments and Methods A476:429-434, 2002.
33. Newhauser WD, Titt U, Dexheimer D, Yan X, Nill S. Neutron shielding verification measurements and simulations for a 235-MeV Proton Therapy Center. Nuclear Instruments and Methods A476:80-84, 2002.
34. Titt U, Dangendorf V, Schuhmacher H. Digital imaging of charged particle track structures with a low pressure optical time projection chamber. Nucl Phys B (Pro Suppl) 78:444-448, 1999.
35. Titt U, Breskin A, Checkhik R, Dangendorf V, Schmidt-Bocking H, Schuhmacher H. A time projection chamber with optical read out for charged particle track sturcture imaging. Nucl Instr & Meth A416:85-89, 1998.
36. Titt U, Breskin A, Chechik R, Dangendorf V, Grobwendt B, Schuhmacher H. Concept of a neutron dosimeter based on a recoil particle track chamber. Radiat Prot Dosim 70:219-224, 1997.

Grant & Contract Support

Title: Intensity Modulated Particle Therapy
Funding Source: Sister Institution Network Fund
Role: Co-Investigator
Duration: 4/1/2011 - 3/31/2013
Title: Optimizing Proton Therapy - Core B: Clinical and Computational Support
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Thomas DeLaney
Duration: 9/25/2008 - 7/31/2014
Title: Optimizing Proton Therapy - Project 3: Reducing Range Uncertainties in Proton Radiation Therapy
Funding Source: NIH/NCI
Role: Project Leader
Principal Investigator: Thomas DeLaney
Duration: 9/25/2008 - 7/31/2014
Title: Optimizing Proton Radiation Therapy
Funding Source: NIH/NCI
Role: Co-Investigator
Principal Investigator: Thomas DeLaney/Radhe Mohan
Duration: 9/25/2008 - 7/31/2013
Title: Deterministic Radiotherapy Dose Evaluation
Funding Source: NIH
Role: Co-Investigator
Duration: 2004 - 2005
Title: Monte Carlo Neutron Shielding of Proton Therapy Facilities
Funding Source: Betchel Infrastructure Corporation
Role: Principal Investigator
Duration: 2001 - 2003

Last updated: 7/3/2013