Vanessa Jensen, DVM
Department of Veterinary Medicine and Surgery, Division of Discovery Science
Present Title & Affiliation
Primary Appointment
Professor, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Department Chair, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Dual/Joint/Adjunct Appointment
Professor, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 1995 | Iowa State University, Ames, Iowa, US, Veterinary Medicine, DVM |
| 1991 | Texas A&M University, College Station, Texas, US, Biomedical Science, BS |
Postgraduate Training
| 1996-1997 | Postdoctoral Research Associate, Immunology and Microbiology, The University of Iowa School of Medicine, Iowa City, Iowa |
Licenses & Certifications
| 2009 | Diplomate of the American College of Laboratory Animal Medicine |
| 2003 | Veterinary License |
| 2000 | Veterinary License |
| 1999 | Veterinary License |
| 1997 | State Board of Veterinary Medical Examiners |
| 1997 | Veterinary License |
Experience & Service
Faculty Academic Appointments
Associate Professor, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2021
Assistant Professor, Veterinary Medicine and Surgery, The University of Texas Health Science Center at Houston, Houston, TX, 2006 - 2015
Administrative Appointments/Responsibilities
Director, Veterinarian Facilities, Department of Veterinary Medicine and Surgery, Veterinary Medicine and Surgery, MD Anderson Texas Medical Center, Houston, TX, 2022 - Present
Veterinary Medicine Lead/ Preclinical Development Lead, Program for Innovative Microbiome and Translational Research (PRIME-TR), The University of Texas MD Anderson Cancer Center, Houston, TX, 2021 - Present
Department Chair, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2019 - Present
Director of Research Animal Support Facility for the Cancer Center Support Grant Core, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - Present
Department Chair ad interim, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2018 - 2019
Deputy Department Chair, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2017 - 2018
Co-Director of Education, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2016 - 2022
Section Chief, Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 2015 - 2018
Residency Program Director, The Gulf Coast Consortium Veterinary Training Program, Houston, 2015 - 2018
Chief of Small Animal Medicine and Surgery, The University of Texas Health Science Center at Houston, Houston, TX, 2012 - 2015
Chief Executive Officer of Preceptor Site, The University of Texas Health Science Center at Houston, Houston, TX, 2007 - 2015
Occupational Health and Safety Program Liaison, The University of Texas Health Science Center at Houston, Houston, TX, 2006 - 2015
Chief of Large Animal Medicine and Surgery, The University of Texas Health Science Center at Houston, Houston, TX, 2006 - 2012
Other Professional Positions
Mentor, American College of Laboratory Animal Medicine Mentoring Committee, Houston, TX, 2019 - Present
Veterinary Consultant, Texas Heart Institute, Houston, 2015 - 2023
IACUC Member, Texas Southern University, Houston, TX, 2014 - 2020
Attending Veterinarian, Texas Southern University, Houston, TX, 2014 - 2020
Attending Veterinarian, Nanospectra Biosciences Inc, Houston, TX, 2012 - Present
IACUC Member, Nanospectra Biosciences Inc, Houston, TX, 2012 - Present
Ad Hoc Consultant/Specialist, Association for Assessment and Accreditation of Laboratory Animal Care – International, Frederick, MD, 2012 - Present
Mentor, American College of Laboratory Animal Medicine Mentoring Committee, Houston, TX, 2009 - 2011
Advisor, Lone Star College Veterinary Technology Program Advisory Committee, Tomball, TX, 2007 - 2023
Clinical Veterinarian, University of Wisconsin, Madison, WI, 2003 - 2006
Surgical Laboratory Supervisor/Clinical Veterinarian, Sierra Biomedical, A Div. of Charles River Laboratories, Inc, Sparks, NV, 2000 - 2003
Assistant Medical Director, VCA I-30 Animal Hospital, Garland, TX, 1999 - 2000
Associate Veterinarian/Relief Veterinarian, Humane Animal Hospital, Plano, TX, 1998 - 2000
Associate Veterinarian, VCA Lakewood Animal Hospital, Dallas, TX, 1998 - 1998
Extramural Institutional Committee Activities
Member, Research-related Federal Developments Task Force, The University of Texas MD Anderson Cancer Center, 2025 - Present
Member, The Genetically Engineered Mouse Facility (GEMF) Advisory Board, The University of Texas MD Anderson Cancer Center, 2024 - Present
Chair, Department of Comparative Medicine/Keeling Center Search Committee,, The University of Texas MD Anderson Cancer Center, 2023 - 2024
Member, Search Committee for the Director, Genetically Engineered Mouse Facility Core (GEMF), The University of Texas MD Anderson Cancer Center, 2022 - 2023
Member, Research Enablement, Activities and Conduct Team (REACT), The University of Texas MD Anderson Cancer Center, 2021 - Present
Member, Leadership Development Council, The University of Texas MD Anderson Cancer Center, 2021 - Present
Chair, Department of Veterinary Medicine and Surgery Search Committee, The University of Texas MD Anderson Cancer Center, 2021 - 2022
Chair, Advisory Committee for Campus Animal Movement, The University of Texas MD Anderson Cancer Center, 2020 - 2022
Leader, Strategic Planning New Vivarium Think Tank, The University of Texas MD Anderson Cancer Center, 2020 - 2024
Member, Research COVID-19 Core Leadership Team (RCCLT), The University of Texas MD Anderson Cancer Center, 2020 - 2021
Executive Sponsor for Animal Related Items, Science Park Executive Steering Committee, The University of Texas MD Anderson Cancer Center, 2020 - 2022
Member, Institutional Midcareer Committee, The University of Texas MD Anderson Cancer Center, 2020 - 2021
Member, TMC3 Science Think Tank Committee, The University of Texas MD Anderson Cancer Center, 2020 - 2022
Member, Endemic COVID-19: Research and Administration Restart Task Force, The University of Texas MD Anderson Cancer Center, 2020 - 2021
Member, Lab Research Ramp-Up Working Group, The University of Texas MD Anderson Cancer Center, 2020 - 2020
Chair, COVID-19 Model Organism Financial Loss Subcommittee, The University of Texas MD Anderson Cancer Center, 2020 - 2020
Member, CoSC COVID-19 Bench Science & Cores Task Force, The University of Texas MD Anderson Cancer Center, 2020 - 2020
Member, COVID-19 Research Incident Command, The University of Texas MD Anderson Cancer Center, 2020 - 2020
Member, Innovations and Procedure-Based Education Center Working group, The University of Texas MD Anderson Cancer Center, 2019 - 2020
Chair, Department of Veterinary Medicine and Surgery Education Steering Committee, The University of Texas MD Anderson Cancer Center, 2019 - Present
Member, Comparative Medicine/Keeling Center Search Committee, The University of Texas MD Anderson Cancer Center, 2019 - 2019
Member, Institutional Animal Care and Use Committee (IACUC) Rodent pathogen subcommittee, The University of Texas MD Anderson Cancer Center, 2019 - 2020
Voting Member, Institutional Service Center Committee, The University of Texas MD Anderson Cancer Center, 2019 - Present
Chair, Department of Veterinary Medicine and Surgery Faculty Search Committee, The University of Texas MD Anderson Cancer Center, 2019 - 2019
Member, Community of Science Chairs, The University of Texas MD Anderson Cancer Center, 2018 - Present
Member, Community of Chairs, The University of Texas MD Anderson Cancer Center, 2018 - Present
Attending Veterinarian and voting member, Institutional Animal Care and Use Committee, The University of Texas MD Anderson Cancer Center, 2018 - Present
Chair, Program Income Advisory Committee, The University of Texas MD Anderson Cancer Center, 2018 - 2024
Member, Department of Veterinary Medicine and Surgery Faculty Search Committee, The University of Texas MD Anderson Cancer Center, 2018 - 2018
Voting Member, Institutional Safety Committee, The University of Texas MD Anderson Cancer Center, 2018 - 2021
Member, Institutional Incident Command Committee, The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, Annual Care Communications Committee, The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, Environmental Health and Safety and Veterinary Medicine Communications Committee, The University of Texas MD Anderson Cancer Center, 2016 - Present
Member, Research Animal Support Facility-Houston Program Income Advisory Committee, The University of Texas MD Anderson Cancer Center, 2016 - 2018
Member, Animal Research Infrastructure Strategic Planning Committee, The University of Texas MD Anderson Cancer Center, 2016 - 2018
Voting Member, Institutional Biosafety Committee, The University of Texas MD Anderson Cancer Center, 2015 - 2021
Alternate Voting Member, Institutional Animal Care and Use Committee, The University of Texas MD Anderson Cancer Center, 2015 - 2018
Training Program Director, Gulf Coast Consortium Postdoctoral Veterinary Training Program in Laboratory Animal Medicine and Science Advisory Committee, The University of Texas MD Anderson Cancer Center, 2014 - 2015
Chair, Assistant Director Search Committee, The University of Texas Health Science Center at Houston, The University of Texas MD Anderson Cancer Center, 2013 - 2014
Voting Member, Radiation Safety Committee, The University of Texas Health Science Center at Houston, The University of Texas MD Anderson Cancer Center, 2012 - 2015
Primary Advisor, Gulf Coast Consortium Postdoctoral Veterinary Training Program in Laboratory Animal Medicine and Science Advisory Committee, The University of Texas MD Anderson Cancer Center, 2012 - 2014
Attending Veterinarian, Voting Member, Animal Welfare Committee (Institutional Animal Care and Use Committee), The University of Texas Health Science Center at Houston, The University of Texas MD Anderson Cancer Center, 2011 - 2015
Member, Animal Care Communications Crisis Management Leadership Committee, The University of Texas Health Science Center at Houston, The University of Texas MD Anderson Cancer Center, 2011 - 2015
Voting Member, Animal Welfare Committee (Institutional Animal Care and Use Committee), The University of Texas Health Science Center at Houston, The University of Texas MD Anderson Cancer Center, 2008 - 2015
Member, Research Risk Assessment Working Group, The University of Texas Health Science Center at Houston, The University of Texas MD Anderson Cancer Center, 2006 - 2007
Voting Member, Institutional Biosafety Committee, University of Texas Health Science Center at Houston, The University of Texas MD Anderson Cancer Center, 2006 - 2012
Ex Officio Member, Animal Welfare Committee (Institutional Animal Care and Use Committee), The University of Texas Health Science Center at Houston, The University of Texas MD Anderson Cancer Center, 2006 - 2008
Member, Clinical Veterinarian Search Committee, University of Wisconsin Medical School, The University of Texas MD Anderson Cancer Center, 2005
Voting Member, Institutional Animal Care and Use Committee, University of Wisconsin Medical School, The University of Texas MD Anderson Cancer Center, 2003 - 2006
Chair, Standard Operating Procedures (SOP) Committee, Sierra Biomedical A Division of Charles River Laboratories, Inc, The University of Texas MD Anderson Cancer Center, 2000 - 2003
Editorial Activities
Review Editor, Frontiers in Physiology, 2023 - Present
Honors & Awards
| 2022 | Honored/Recognized at MD Anderson's 80th Anniversary Celebration, MD Anderson |
| 2018 | Administrative Leadership Program & Faculty Leadership Academy Cohorts XXII, The University of Texas MD Anderson Cancer Center |
| 2018 | Julie and Ben Rogers Award for Excellence, Finalist, The University of Texas MD Anderson Cancer Center |
| 2017 | Letter of Commendation, MD Anderson IACUC Chair & VP, Deputy Chief Academic Officer & Division Head of Science |
| 2017 | Outstanding Clinical Veterinarian Award, Charles River Laboratories |
| 1994 | Ralph O. Fuehring Memorial Scholarship |
| 1991 | Hill's Pet Products, Inc. Scholarship |
| 1988 - 1989 | National Dean's List of University Students |
| 1987 - 1988 | Outstanding College Students of America |
Professional Memberships
Selected Presentations & Talks
Local Presentations
- 2026. Safety Moment. Invited. Strategy Leaders Forum. Houston, Texas, US.
- 2025. Squeaky Clean Research: The Animals, Vet Med and You. Invited. The University of Texas MD Anderson Cancer Center. Houston, Texas, US.
- 2024. Understanding Our Breakthroughs Lecture Series: From Bench to Bedside with Animals. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2024. Research Town Hall: Progress Review on Biosciences Research Facility. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2024. Cancer Center CCSG NIH EAB 2024. Poster. The University of Texas MD Anderson Cancer Center. Houston, Texas, US.
- 2024. BRF Design Review with Q&A. Conference. The University of Texas MD Anderson Cancer Center: External Advisory Board for Biosciences Research Building (BRF). Houston, TX, US.
- 2024. Research Town Hall: Animal Transport. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2023. Research Town Hall: Safety Moment. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2023. Husbandry in Technology and the Digital World. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2022. NCI PREVENT Cancer Program: Research Animal Support Facility Houston. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2022. Research Education: From Bench to Bedside: The Role of Animals in Clinical Research. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2019. Current Capabilities for Microbiome in Mouse Models. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2019. Animal Welfare, 2019-20 Responsible Conduct of Research (RCR) lecture. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2019. Animal Research in Head and Neck Cancer-Part 1. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
- 2018. From Bench to Bedside: The Role of Animals in Clinical Research. Conference. The University of Texas MD Anderson Cancer Center. Houston, TX, US.
Regional Presentations
- 2022. Struvite Urolithiasis in a Tg (KRT14 cre)1Amc/J Mouse. Conference. Texas Branch American Association for Laboratory Animal Science. Sugarland, TX, US.
- 2020. The Connection with the Microbiome and Cancer. Conference. Texas Branch American Association for Laboratory Animal Science,58th Annual Meeting. San Marcos, TX, US.
- 2018. Patient Derived Xenograft Model Development and Biosafety. Conference. Texas Branch American Association for Laboratory Animal Science, 56th Annual Meeting. College Station, TX, US.
- 2014. Peritoneal Mesothelioma in a Ferret. Conference. Texas Branch American Association for Laboratory Animal Science, 52nd Annual Meeting. Sugar Land, TX, US.
- 2010. Erythematous Dermatitis in a Rhesus Macaque. Conference. Texas Branch American Association for Laboratory Animal Science, 48th Annual Meeting. College Station, TX, US.
National Presentations
- 2025. Phased Vivarium Projects for Future Agility: Program, Funding, Innovation Advantages (Part II). Invited. Tradeline’s 36th Annual Animal Research Facilities Conference. San Diego, California, US.
- 2025. Phased Vivarium Projects for Future Agility: Program, Funding, Innovation Advantages (Part I). Invited. Tradeline’s 36th Annual Animal Research Facilities Conference. San Diego, California, US.
- 2019. Macrophage-Activation Syndrome in Humanized NOD.Cg-PrkdcscidIl2rgtm1wjl /SzJ (NSG) Expressing Human Cytokines IL-3, GM-CSF, and SF (NSG-SGM3) After Engraftment with Human CD34+ Hematopoietic Stem Cells (Poster). Conference. 2019 Annual Meeting American College of Veterinary Pathologists. Houston, TX, US.
- 2019. The Connection Between Cancer and the Microbiome with an Emphasis on the Gut. Invited. 2019 Annual Meeting American College of Veterinary Pathologists. San Antonio, TX, US.
- 2019. Minisymposium - Pathobiology of Bacterial, Viral and Parasitic Diseases. Conference. American Society for Investigative Pathology. Orlando, FL, US.
- 2018. Variation of the Gut Microbiome of Complete Responders to Immune Checkpoint Blockade and Healthy Individuals- Implications for Clinical Trial Design. Conference. Immune Checkpoint Blockade and Healthy Individuals- Implications for Clinical Trial Design. Society for Immunotherapy of Cancer (SITC). Washington, DC, MD, US.
- 2018. The Dirty Truth: Sanitation of Electronic Devices. Conference. 69th Annual American Association for Laboratory Animal Science. Baltimore, MD, US.
- 2018. The Quatranasia: A Multi-Chamber Euthanasia Unit. Conference. 69th American Association for Laboratory Animal Science. Baltimore, MD, US.
- 2018. Keeping the "Known" in Gnotobiotics: A Minimalist Approach. Conference. 56th Annual Texas Branch American Association of Laboratory Animal Science. College Station, TX, US.
- 2017. Housing Practice of Patient Derived Xenograft Models. Invited. National American Association for Laboratory Animal Science, 68th Annual Meeting. Austin, TX, US.
- 2014. O.: Coordinated Regulation of ENaC activity in the distal nephron by Aldosterone and Ang II. Invited. Experimental Biology Meeting. San Diego, CA, US.
- 2013. Efficacy of a Novel Foam E-collar to Promote Comfort and to Inhibit Self-Mutilation during Postsurgical Recovery in the Watanabe Rabbit and Rodents. Conference. 64th Annual American Association for Laboratory Animal Science. Baltimore, MD, US.
International Presentations
- 2025. Basic Set-up for Microbiome Research Management and Health Monitoring. Invited. The 16th TALAS International Conference. Bangkok, TH.
- 2025. Common IACUC Issues Case Scenarios. Panelist. The 16th TALAS International Conference. Bangkok, TH.
- 2025. Regulations and Animal Care in Cancer Models: Focus on Patient-Derived Xenografts (PDX) and Microbiome Studies. Invited. The 16th TALAS International Conference. Bangkok, TH.
- 2018. Setting Up a Gnotobiotic System Using IVCs. Invited. Thailand Association of Laboratory Animal Science. Bangkok, TH.
- 2018. How to Set Up and Maintain Patient-Derived Xenograft (PDX) Colonies in IVCs. Invited. Thailand Association of Laboratory Animal Science. Bangkok, TH.
- 2016. Animal Models in Cancer Nanotechnology- Nanotechnology in Non-Rodent Models. Invited. Asian Federation of Laboratory Animal Science Associations. Singapore, SG.
Formal Peers
- 2022. Visit from the Association for Assessment and Accreditation for Laboratory Animal Science (AAALAC, International). Invited. Houston, TX, US.
- 2022. Animal Facility Access During Staff Shortages. Invited. Houston, TX, US.
- 2021. Animal Patients- Animal Research in Science and Medicine. Invited. Tomball, TX, US.
- 2011. Expanding the Medical School’s Research Capabilities with the Medical School Extension Building and Its Vivarium. Invited. Houston, TX, US.
Grant & Contract Support
| Date: | 2024 - Present |
| Title: | Cancer Center Support (CORE) Grant |
| Funding Source: | NCI/NIH |
| Role: | Co-I |
| ID: | 4P30CA016672-48 |
| Date: | 2023 - Present |
| Title: | University of Texas PDX Development and Trial Center |
| Funding Source: | NIH |
| Role: | Co-I |
| ID: | U54CA224065 |
| Date: | 2021 - Present |
| Title: | Using Patient-Derived Xenografts for Fighting Cancer in Texas |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| ID: | PAR-20-131 |
| Date: | 2021 - Present |
| Title: | Mouse models of Leukemia |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2020 - 2025 |
| Title: | Establishment of Translational Microbiome Core Services |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Co-I |
| Date: | 2020 - 2025 |
| Title: | Next-Generation Translational Microbiome Center |
| Funding Source: | Cancer Prevention & Research Institute of Texas (CPRIT) |
| Role: | Collaborator |
| ID: | RP200591 |
| Date: | 2019 - 2024 |
| Title: | Cancer Center Support (CORE) Grant |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 2P30CA016672-43 |
| Date: | 2019 - 2024 |
| Title: | Cancer Center Support (CORE) Grant |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| Date: | 2018 - 2019 |
| Title: | Exercise to Decrease the Rate of Metastasis and Improve Chemotherapeutic |
| Funding Source: | Conquer Cancer Foundation |
| Role: | Collaborator |
| ID: | FP00003724 |
| Date: | 2018 - 2019 |
| Title: | Characterizing the potential for drugstore beetles (Stegobium paniceum) as reservoir or vector of pathogens in a rodent vivarium |
| Funding Source: | Amer Assoc for Laboratory Animal Sci |
| Role: | Co-PI |
| Date: | 2017 - 2023 |
| Title: | University of Texas PDX Development and Trial Center |
| Funding Source: | NIH/NCI |
| Role: | Co-I |
| ID: | 1U54CA224065-1 |
| Date: | 2013 - 2018 |
| Title: | The Gulf Coast Consortium Veterinary Training Program in Comparative Medicine |
| Funding Source: | NIH/NCI |
| Role: | Co-PI |
| ID: | 5R25OD014808-03 |
Selected Publications
Peer-Reviewed Articles
- Zhang R, Khare P, Jensen VB, Banerjee P, Ivan C, Schneider S, Barbaglio F, Clise-Dwyer K, Thompson E, Mendoza M, Chiorazzi N, Chen S, Joy Yan XJ, Jain N, Ghia P, Caligaris-Cappio F, Mendonsa R, Kasimsetty S, Swoboda R, Bayraktar R, Wierda W, Gandhi V, Calin G, Keating MJ, Bertilaccio MTS. The DLEU2/miR-15a/miR-16-1 cluster shapes the immune microenvironment of chronic lymphocytic leukemia. Blood Cancer J 14(1):168, 2024. e-Pub 2024. PMID: 39438453.
- Devarajan E, Davis RE, Beird HC, Wang WL, Jensen VB, Jayakumar A, Leung CH, Lin HY, Wu CC, Ihezie SA, Tsai JW, Futreal PA, Lewis VO. Targeting IL-11R/EZH2 signaling axis as a therapeutic strategy for osteosarcoma lung metastases. Discovery Oncology 15(1):232, 2024. e-Pub 2024. PMID: 38886296.
- DiPeri, TP, Evans, KW, Wang, B, Zhao, M, Akcakanat, A, Raso, G, Rizvi, YQ, Zheng, X, Korkut, A, Varadarajan, K, Uzunparmak, B, Ileana Dumbrava, EE, Pant, S, Ajani, JA, Pohlmann, PR, Jensen, VB, Javle, M, Rodon Ahnert, J, Meric-Bernstam, F. Co-clinical Trial of Novel Bispecific Anti-HER2 Antibody Zanidatamab in Patient-Derived Xenografts. Cancer Discovery 14(5):828-845, 2024. e-Pub 2024. PMID: 38358339.
- Sun, H, Cao, S, Mashl, RJ, Mo, CK, Zaccaria, S, Wendl, MC, Davies, S, Bailey, MH, Primeau, T, Hoog, J, Mudd, JL, Dean, DA, Patidar, R, Chen, L, Wyczalkowski, MA, Jayasinghe, R, Rodrigues, FM, Terekhanova, NV, Li, Y, Lim, KH, Wang-Gillam, A, Van Tine, BA, Ma, C, Aft, R, Fuh, KC, Schwarz, JK, Roth, JA, Tapia, C, Yang, F, Akcakanat, A, Chen, H, Dai, B, Gibbons, DL, Ha, MJ, Jensen, VB, Kim, M, Kopetz, S, Menter, DG, Meraz, I, Sorokin, A, Wang, J, Westin, SN, Xi, Y, Yap, TA, Yennu Nanda, VG, Zhang, X, Zheng, X, Davies, MA, Fang, B, Meric-Bernstam, F. Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment. Nature communications 13(1), 2022. e-Pub 2022. PMID: 34996889.
- Schwabkey Z, Wiesnoski DH, Chang C, Tsai W, Pham D, Ahmed SS, Hayase T, Ortega MR, El-Himri RK, Sanchez CA, Hayase E, Frenk AC, Miyama T, Halsey TM, Heckel BE, Brown A, Jin Y, Lorenzi PL, Warmoes MO, Tan L, Swennes AG, Jensen VB, Peterson CB, Do K, Zhang L, Shi Y, Wang Y, Galloway-Pena J, Okhuysen P, Daniel-MacDougall C, Shono Y, Burgos da Silva M, Peled J, Van den Brink MRM, Ajami NJ, Wargo JA, Rondon G, Srour SA, Mehta RS, Alousi AM, Shpall EJ, Champlin EJ, Shelburne SA, Molldrem JJ, Mohamed AJ, Karmouch JL, Jenq RR. Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment. Science Translational Medicine 14(671), 2022. e-Pub 2022. PMID: 36383683.
- Schwabkey, Z, Wiesnoski, DH, Chang, C, Tsai, W, Pham, D, Ahmed, SS, Hayase, T, Ortega Turrubiates, MR, El-Himri, RK, Sanchez, CA, Hayase, E, Frenk Oquendo, AC, Miyama, T, Halsey, T, Heckel, BE, Brown, AN, Jin, Y, Raybaud, M, Prasad, R, Flores, I, McDaniel, L, Chapa, V, Lorenzi, PL, Warmoes, MO, Tan, L, Swennes, AG, Fowler, S, Conner, ME, McHugh, K, Graf, T, Jensen, VB, Peterson, CB, Do, K, Zhang, L, Shi, Y, Wang, Y, Galloway-Pena, J, Okhuysen, PC, Daniel-MacDougall, CR, Shono, Y, Burgos da Silva, M, Peled, JU, Van Den Brink, MR, Ajami, NJ, Wargo, J, Reddy, P, Valdivia, RH, Davey, L, Rondon, G, Srour, S, Mehta, RS, Alousi, AM, Shpall, E, Champlin, RE, Shelburne, S, Molldrem, JJ, Jamal, M, Karmouch, J, Jenq, RR. Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment. Science Translational Medicine 14(671), 2022. e-Pub 2022. PMID: 36383683.
- Behrana Jensen V, Humphreys AF, Pageon LR, Samuels DL, Trimble AL, Mendoza A, Whitley EM. Malignant Peritoneal Mesothelioma in a Young Adult Ferret (Mustela putorius furo). JAVMA 259(S2):1-4, 2022. e-Pub 2022. PMID: 35349477.
- Spencer, C, McQuade, JL, Gopalakrishnan, V, McCulloch, JA, Vétizou, M, Cogdill, AP, Wadud Khan, MA, Zhang, X, White, MG, Peterson, CB, Wong, MC, Morad, G, Rodgers, TE, Badger, JH, Helmink, BA, Andrews, MC, Rodrigues, RR, Morgun, A, Kim, YS, Roszik, J, Hoffman, KL, Zheng, JL, Zhou, Y, Medik, YB, Kahn, LS, Johnson, S, Hudgens, CW, Wani, K, Gaudreau, PO, Harris, AL, Jamal, M, Baruch, EN, Perez-Guijarro, E, Day, CP, Merlino, G, Pazdrak, B, Lochmann, BS, Szczepaniak Sloane, RA, Arora, R, Anderson, JE, Zobniw, C, Posada, E, Sirmans, E, Simon, JM, Haydu, LE, Burton, EM, Wang, L, Dang, M, Dwyer, KC, Schneider, S, Chapman, T, Anang, NA, Duncan, S, Toker, J, Malke, J, Glitza, IC, Amaria, RN, Tawbi, H, Diab, A, Wong, MK, Patel, SP, Woodman, SE, Davies, MA, Ross, MI, Gershenwald, JE, Lee, JE, Hwu, P, Jensen, VB, Samuels, Y, Straussman, R, Ajami, NJ, Nelson, KC, Nezi, L, Petrosino, JF, Futreal, A, Lazar, A, Hu, J, Jenq, RR, Tetzlaff, M, Yan, Y, Garrett, WS, Huttenhower, C, Sharma, P, Watowich, SS, Allison, JP, Cohen, L, Trinchieri, G, Daniel-MacDougall, CR, Wargo, J. Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response. Science 374(6575):1632-1640, 2021. e-Pub 2021. PMID: 34941392.
- Woo, XY, Giordano, J, Srivastava, A, Zhao, ZM, Lloyd, M, de Bruijn, R, Suh, YS, Patidar, R, Chen, L, Scherer, S, Bailey, M, Yang, CH, Cortes-Sanchez, E, Xi, Y, Wang, J, Wickramasinghe, JM, Kossenkov, AV, Rebecca, VW, Sun, H, Mashl, RJ, Davies, S, Jeon, R, Frech, C, Randjelovic, J, Rosains, J, Galimi, F, Bertotti, A, Lafferty, A, O’Farrell, AC, Modave, E, Fang, B, Roth, JA, Meric-Bernstam, F, Davies, MA, Zheng, X, Zhang, X, Akcakanat, A, Yap, TA, Ha, MJ, Chen, H, Kopetz, S, Menter, DG, Westin, SN, Kim, M, Dai, B, Gibbons, DL, Tapia, C, Jensen, VB, Yennu Nanda, VG, Mælandsmo, GM. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nature Genetics 53(5):761, 2021. e-Pub 2021. PMID: 33608693.
- Hennessy M, Wahba A, Felix K, Cabrera M, Segura MG, Kundra V, Ravoori MK, Stewart J, Kleinerman ES, Jensen VB, Gopalakrishnan V, Pena R, Quach P, Kim G, Kivimäe S, Madakamutil L, Overwijk WW, Zalevsky J, Gordon N. Bempegaldesleukin (BEMPEG; NKTR-214) Efficacy as a Single Agent and in Combination with Checkpoint-Inhibitor Therapy in Mouse Models of Osteosarcoma. Int J Cancer 148(8):1928-1937, 2021. e-Pub 2021. PMID: 33152115.
- Chen Y, Zhang R, Wang L, Correa AM, Pataer A, Xu Y, Zhang X, Ren C, Wu S, Meng QH, Fujimoto J, Jensen VB, Antonoff MB, Hofstetter WL, Mehran RJ, Pisimisis G, Rice DC, Sepesi B, Vaporciyan AA, Walsh GL, Swisher SG, Roth JA, Heymach JV, Fang B. Tumor Characteristics Associated with Engraftment of Patient-Derived Non-Small Cell Lung Cancer Xenografts in Immunocompromised Mice. Cancer 125(21):3738-3748, 2019. e-Pub 2019. PMID: 31287557.
- Fowlkes NW, Swain J, Gagea M, Lockworth C, Tinkey P, Jensen VB, Whitley E. Cutaneous and Gastrointestinal Dysbiosis in Immunodeficient Mice. The FASEB Journal 33(S1):38-5, 2019. e-Pub 2019.
- Yan X, Zhang X, Wang L, Zhang R, Pu X, Wu S, Li L, Tong P, Wang J, Meng QH, Jensen VB, Girard L, Minna JD, Roth JA, Swisher SG, Heymach JV, Fang B. Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis. Cancer Res 79(1):125-132, 2019. e-Pub 2019. PMID: 30401714.
- Levy DR, Flores R, Garcia GE, Craig SL, Jensen VB. Effects of Extruded Compared with Pelleted Diets on Laboratory Mice Housed in Individually Ventilated Cages and the Cage Environment. J Am Assoc Lab Anim Sci 57(6):686-694, 2018. e-Pub 2018. PMID: 30185286.
- . Abstracts of Scientific Presentations 2018 AALAS National Meeting Baltimore, Maryland. J Am Assoc Lab Anim Sci 57(5):534-642, 2018. e-Pub 2018. PMID: 30236173.
- Mamenko M, Zaika O, Tomilin V, Jensen VB, Pochynyuk O. Compromised regulation of the collecting duct ENaC activity in mice lacking AT1areceptor. J Cell Physiol 233(9):7217-7225, 2018. e-Pub 2018. PMID: 29574718.
- Gopalakrishnan V, Spencer CN, Nezi L, Reuben A, Andrews MC, Karpinets TV, Prieto PA, Vicente D, Hoffman K, Wei SC, Cogdill AP, Zhao L, Hudgens CW, Hutchinson DS, Manzo T, Petaccia de Macedo M, Cotechini T, Kumar T, Chen WS, Reddy SM, Szczepaniak Sloane R, Galloway-Pena J, Jiang H, Chen PL, Shpall EJ, Rezvani K, Alousi AM, Chemaly RF, Shelburne S, Vence LM, Okhuysen PC, Jensen VB, Swennes AG, McAllister F, Marcelo Riquelme Sanchez E, Zhang Y, Le Chatelier E, Zitvogel L, Pons N, Austin-Breneman JL, Haydu LE, Burton EM, Gardner JM, Sirmans E, Hu J, Lazar AJ, Tsujikawa T, Diab A, Tawbi H, Glitza IC, Hwu WJ, Patel SP, Woodman SE, Amaria RN, Davies MA, Gershenwald JE, Hwu P, Lee JE, Zhang J, Coussens LM, Cooper ZA, Futreal PA, Daniel CR, Ajami NJ, Petrosino JF, Tetzlaff MT, Sharma P, Allison JP, Jenq RR, Wargo JA. Gut Microbiome Modulates Response to anti-PD-1 Immunotherapy in Melanoma Patients. Science 359(6371):97-103, 2018. e-Pub 2018. PMID: 29097493.
- Prieto MC, Reverte V, Mamenko M, Kuczeriszka M, Veiras LC, Rosales CB, McLellan M, Gentile O, Jensen VB, Ichihara A, McDonough AA, Pochynyuk OM, Gonzalez AA. Collecting Duct Prorenin Receptor Knockout Reduces Renal Function, Increases Na+ Excretion and Mitigates Renal Responses in ANGII Induced Hypertensive Mice. Am J Physiol Renal Physiol 313(6):152, 2017. e-Pub 2017. PMID: 28814438.
- Duran AF, Gopalakrishnan V, Guio J, Roberts K, Nezi L, Wargo J, Jensen VB. Did You Know About IVC Gnotobiotics?. LAS Pro 5(4):47-49, 2017. e-Pub 2017.
- Mamenko MV, Boukelmoune N, Tomilin VN, Zaika OL, Jensen VB, O'Neil RG, Pochynyuk OM. The Renal TRPV4 Channel is Essential for Adaptation to Increased Dietary Potassium. Kidney Int 91(6):1398-1409, 2017. e-Pub 2017. PMID: 28187982.
- Wafer LN, Jensen VB, Whitney JC, Gomez TH, Flores R, Goodwin BS. Environmental Enrichment Influences Fertility and Fecundity of Zebrafish (Danio rerio). J Am Assoc Lab Anim Sci 55(3):291-294, 2016. e-Pub 2016. PMID: 27177561.
- Wafer LN, Whitney JC, Jensen VB. Argulus japonicus in Goldfish (Carassius auruatus). Comp Med 65(2):93-95, 2015. e-Pub 2015. PMID: 25926394.
- Mamenko M, Zaika O, Prieto MC, Jensen VB, Doris PA, Navar LG, Pochynyuk O. Coordinated regulation of ENaC activity in the distal nephron by aldosterone and Ang II (1088.14). The FASEB Journal 28(1), 2014. e-Pub 2014.
- Mamenko M, Zaika O, Prieto MC, Jensen VB, Doris PA, Navar LG, Pochynyuk O. Chronic Angiotensin II Infusion Drives Extensive Aldosterone-Independent ENaC activation. Hypertension 62(6):1111-1122, 2013. e-Pub 2013. PMID: 24060890.
- Work R, Jensen VB. Infant Pants, A Different Approach to Bunny Bandaging. AALAS 1(3):39-40, 2013. e-Pub 2013.
- Munger RJ, Jensen VB, Bouldin TW, Peiffer RL. Bilateral Neuroepithelial Choristomas of the Optic Disc in a Cynomolgus Monkey (Macaca Fascicularis): A Case Report. Vet Ophthalmol 5(3):221-226, 2002. e-Pub 2002. PMID: 12236876.
- Jensen VB, Harty JT, Jones BD. Interactions of the Invasive Pathogens Salmonella typhimurium, Listeria monocytogenes, and Shigella flexneri with M Cells and Murine Peyer’s Patches. Infect Immun 66(8):3758-3766, 1998. e-Pub 1998. PMID: 9673259.
Invited Articles
- Barrera A, Duran AF, Mitchell JM, Jensen VB. Rescue Me: Sanitation of Electronic Devices. LAS Pro 7(3):60-61, 2019. e-Pub 2019.
- Bird NK, Greaver JL, Trimble AL, Stavinoha CI, Work RK, Jensen VB. Efficacy of a Novel Foam E-collar to Promote Comfort and to Inhibit Self-mutilation During Postsurgical Recovery in the Watanabe Rabbits with Potential Use in Rodents. AALAS 2(3):48-50, 2014. e-Pub 2014.
Abstracts
- Moore EJ, Fowlkes NW, Jensen VB. Struvite Urolithiasis in a Tg(KRT14-cre)1Amc/J Mouse. Annual Texas Branch of the American Association of Laboratory Animal Science Meeting, 2022. e-Pub 2022.
- Toker J, Johnson SE, Arora R, Khan, Medik YB, Zhou Y, Serrudo L, MAW, Cogdill AP, Helmink BA, Spencer CN, Gopalakrishnan V, Thakur R, Andrews MC, Jensen V, Martin L, Guio J, Watowich SS, Wargo JA. Influence of OTC Probiotic Use on Gut Microbiome and Response to Immune Checkpoint Blockade Therapy. AACR Virtual Annual Meeting 2020, 2020. e-Pub 2020.
- Fowlkes N, Whitley E, Gagea M, Swain J, Lockworth C, Ueno N, Jensen VB. Macrophage Activation Syndrome in Humanized NOD.CGPRKDCSIDIL2RGTM1WJL/SZJ (NSG) Expressing Human Cytokines IL-3, GM-CSF, and SCF (NSG-SGM3) After Engraftment with Human CD34+ Hematopoietic Stem Cells. American College of Veterinary Pathologists Conference, 2019. e-Pub 2019.
- Fowlkes NW, Swain J, Gagea M, Lockworth C, Tinkey P, Jensen V, Whitley EM. Cutaneous and Gastrointestinal Dysbiosis in Immunodeficient Mice. The FASEB Journal 33(S1):38.5, 2019. e-Pub 2019.
- Helmink B, Harris A, Heffernan T, Andrews M, Cogdill A, Jamal M, Spencer C, Gopalakrishnan V, Gaudreau P, Jenq R, McQuade J, Jensen VB, Duran A, Martin L Gershenwald J, Wargo J. Variation of the Gut Microbiome of Complete Responders to Immune Checkpoint Blockade and Healthy Individuals - Implications for Clinical Trial Design. Society for Immunotherapy of Cancer (SITC) 33rd Annual Meeting, 2018. e-Pub 2018.
- Barrera A, Duran A, Mitchell J, Tinkey P, Jensen VB. The Dirty Truth: An Electronic Device Sanitation Study. 69th Annual American Association for Laboratory Animal Science, 2018. e-Pub 2018. PMID: 30236173.
- Steckler R, Pesek A, Knoblauch J, Rochford J, Jensen VB. The Quatranasia: A Multi-Chamber Euthanasia Unit. 2018 AALAS National Meeting 57(5):534-642, 2018. e-Pub 2018.
- Morrell M, Zhang A, Jensen V, Alvarez C, Schadler K. Exercise Impacts Tumor Vasculature and Metastasis in Ewing Sarcoma. 2017 Connective Tissue Oncology Society Annual Meeting, 2017. e-Pub 2017.
- Jensen VB. Housing Practice of Patient Derived Xenograft Models. AALAS 68th National Meeting, 2017. e-Pub 2017.
- Humphreys AF, Pageon L, Trimble AL, Mendoza A, Schwiebert R, Jensen, VB. Peritoneal Mesothelioma in a Ferret. 52nd Annual Texas Branch American Association for Laboratory Animal Science, 2014. e-Pub 2014.
- Bird NK, Greaver JL, Trimble AL, Stavinoha CI, Work RK, Jensen VB. Efficacy of a Novel Foam E-collar to Promote Comfort and to Inhibit Self-Mutilation During Postsurgical Recovery in the Watanabe Rabbit and Rodents. 64th Annual American Association for Laboratory Animal Science, 2013. e-Pub 2013.
- Moore EJ, Fowlkes NW, Jensen VB. Struvite Urolithiasis in a Tg(KRT14-cre)1Amc/J Mouse. 74th National American Association of Laboratory Animal Science Meeting.
Book Chapters
- Jensen Behrana V, Craig SL. Animal Cancer Therapy Models – Ready Translation to Humans. In: Locoregional Radionuclide Cancer Therapy: Clinical and Scientific Aspects. Springer International Publishing, 189-223, 2020.
- Craig S, Jensen VB. Animal Models in Cancer Nanotechnology. In: Nanotechnology in Cancer. Elsevier Inc, 45-69, 2016.
Web Publications
- Barrera A, Duran AF, Mitchell JM, Jensen VB. Rescue Me: Sanitation of Electric Devices, 2019.
Patient Reviews
CV information above last modified July 22, 2026