Weiliang Du, Ph.D.

Peer-Reviewed Articles

1. Hassanzadeh C, Kuban D, Pasyar S, Bassett R, Troncoso P, Ansari M, Schlembach P, McGuire S, Nguyen Q, Frank S, Mok H, Mohamad O, Park R, Tang C, Du W, Kudchadker R, Choi S, Hoffman K. Hypofractionated, Dose-Escalated Radiation Versus Conventionally Fractionated Radiation for Localized Prostate Cancer: Long-Term Update of a Phase III, Prospective, Randomized Controlled Trial. J Clin Oncol 43(18):JCO2402057, 2025. e-Pub 2025. PMID: 40367400.
2. Du W. High-precision localization of radiation isocenter using Winston-Lutz test: Impact of collimator angle, phantom position, and field size. J Appl Clin Med Phys 26(4):e70000, 2025. e-Pub 2025. PMID: 39904583.
3. Tang C, Sherry AD, Haymaker C, Bathala T, Liu S, Fellman B, Cohen L, Aparicio A, Zurita AJ, Reuben A, Marmonti E, Chun SG, Reddy JP, Ghia A, McGuire S, Efstathiou E, Wang J, Wang J, Pilie P, Kovitz C, Du W, Simiele SJ, Kumar R, Borghero Y, Shi Z, Chapin B, Gomez D, Wistuba I, Corn PG. Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic Prostate Cancer: The EXTEND Phase 2 Randomized Clinical Trial. JAMA Oncol 9(6):825-834, 2023. e-Pub 2023. PMID: 37022702.
4. Moreno A, Solanki AA, Xu T, Lin R, Palta J, Daugherty E, Hong D, Hong J, Kamran SC, Katsoulakis E, Brock K, Feng M, Fuller C, Mayo C, Cancer Consortium BP. Identification of Key Elements in Prostate Cancer for Ontology Building via a Multidisciplinary Consensus Agreement. Cancers 15(12), 2023. e-Pub 2023. PMID: 37370731.
5. Gao S, Muruganandham M, Du W, Ohrt J, Kudchadker RJ, Balter PA. Adding customized electron energy beams to TrueBeam linear accelerators. J Appl Clin Med Phys 23(7):e13633, 2022. e-Pub 2022. PMID: 35533212.
6. Fang R, Yang J, Du W, Court L. Automatic detection of graticule isocenter and scale from kV and MV images. J Appl Clin Med Phys 20(4):18-28, 2019. e-Pub 2019. PMID: 30843335.
7. Hoffman KE, Voong KR, Levy LB, Allen PK, Choi S, Schlembach PJ, Lee AK, McGuire SE, Nguyen Q, Pugh TJ, Frank SJ, Kudchadker RJ, Du W, Kuban DA. Randomized Trial of Hypofractionated, Dose-Escalated, Intensity-Modulated Radiation Therapy (IMRT) Versus Conventionally Fractionated IMRT for Localized Prostate Cancer. J Clin Oncol 36(29):2943-2949, 2018. e-Pub 2018. PMID: 30106637.
8. Du W, Gao S, Jiang W, Kudchadker RJ. Independent evaluation of the effectiveness of IsoCal in improving image center accuracy on Varian TrueBeam and Clinac machines. J Appl Clin Med Phys 19(5):483-490, 2018. e-Pub 2018. PMID: 29956463.
9. Hoffman KE, Skinner H, Pugh TJ, Voong KR, Levy LB, Choi S, Frank SJ, Lee AK, Mahmood U, McGuire SE, Schlembach PJ, Du W, Johnson J, Kudchadker RJ, Kuban DA. Patient-reported urinary, bowel and sexual function after hypofractionated intensity-modulated radiation therapy for prostate cancer: results from a randomized trial. Am J Clin Oncol 41(6):558-567, 2018. e-Pub 2018. PMID: 27635624.
10. Du W, Johnson JL, Jiang W, Kudchadker RJ. On the selection of gantry and collimator angles for isocenter localization using Winston-Lutz tests. J Appl Clin Med Phys 17(1):167-178, 2016. e-Pub 2016. PMID: 28297475.
11. Dhanesar SK, Lim TY, Du W, Bruno TL, Frank SJ, Kudchadker RJ. Evaluation of the MIM Symphony treatment planning system for low-dose-rate- prostate brachytherapy. J Appl Clin Med Phys 16(5):62-75, 2015. e-Pub 2015. PMID: 28296095.
12. Gao S, Du W, Balter P, Munro P, Jeung A. Evaluation of IsoCal geometric calibration system for Varian linacs equipped with on-board imager and electronic portal imaging device imaging systems. J Appl Clin Med Phys 15(3):4688, 2014. e-Pub 2014. PMID: 24892342.
13. Hoffman KE, Voong KR, Pugh TJ, Skinner H, Levy LB, Takiar V, Choi S, Du W, Frank SJ, Johnson J, Kanke J, Kudchadker RJ, Lee AK, Mahmood U, McGuire SE, Kuban DA. Risk of late toxicity in men receiving dose-escalated hypofractionated intensity modulated prostate radiation therapy: results from a randomized trial. Int J Radiat Oncol Biol Phys 88(5):1074-1084, 2014. e-Pub 2014. PMID: 24661661.
14. Du W, Cho SH, Zhang X, Hoffman KE, Kudchadker RJ. Quantification of beam complexity in intensity-modulated radiation therapy treatment plans. Med Phys 41(2):021716, 2014. e-Pub 2014. PMID: 24506607.
15. Li X, Quan EM, Li Y, Pan X, Zhou Y, Wang X, Du W, Kudchadker RJ, Johnson JL, Kuban DA, Lee AK, Zhang X. A fully automated method for CT-on-rails-guided online adaptive planning for prostate cancer intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys 86(5):835-41, 2013. e-Pub 2013. PMID: 23726001.
16. Pair ML, Du W, Rojas HD, Kanke JE, McGuire SE, Lee AK, Kuban DA, Kudchadker RJ. Dosimetric effects of weight loss or gain during volumetric modulated arc therapy and intensity-modulated radiation therapy for prostate cancer. Med Dosim 38(3):251-4, 2013. e-Pub 2013. PMID: 23540491.
17. Likhacheva A, Palmer M, Du W, Brown PD, Mahajan A. Intensity modulated radiation therapy class solutions in Philips Pinnacle treatment planning for central nervous system malignancies: standardized, efficient, and effective. Pract Radiat Oncol 2(4):e145-e153, 2012. e-Pub 2012. PMID: 24674178.
18. Yang M, Du W, Frank S, Pugh T, Bruno T, Kudchadker R. SU-E-T-260: Radiation Exposure Estimation for 131Cs Prostate Implant Patient Release Determination. Med Phys 39(6Part13):3763, 2012. e-Pub 2012. PMID: 28517343.
19. Du W, Gao S, Wang X, Kudchadker RJ. Quantifying the gantry sag on linear accelerators and introducing an MLC-based compensation strategy. Med Phys 39(4):2156-62, 2012. e-Pub 2012. PMID: 22482636.
20. Du W, Gao S. Measuring the wobble of radiation field centers during gantry rotation and collimator movement on a linear accelerator. Med Phys 38(8):4575-4578, 2011. e-Pub 2011. PMID: 21928629.
21. Yang JN, Ding X, Du W, Pino R. Model-based calculations of off-axis ratio of conic beams for a dedicated 6MV radiosurgery unit. Med Phys 37(10):5542-5547, 2010. e-Pub 2010. PMID: 21089780.
22. Du W, Yang JN, Chang EL, Luo D, McAleer MF, Shiu A, Martel MK. A quality assurance procedure to evaluate cone-beam CT image center congruence with the radiation isocenter of a linear accelerator. J Appl Clin Med Phys 11(4):15-26, 2010. e-Pub 2010. PMID: 21081890.
23. Du W, Yang J, Luo D, Martel M. A simple method to quantify the coincidence between portal image graticules and radiation field centers or radiation isocenter. Med Phys 37(5):2256-2263, 2010. e-Pub 2010. PMID: 20527559.
24. Du W, Yang J. A robust Hough transform algorithm for determining the radiation centers of circular and rectangular fields with subpixel accuracy. Phys Med Biol 54(3):555-567, 2009. e-Pub 2009. PMID: 19124954.
25. Wang X, Du W, Smith SA, Stovall M, Buchholz TA, Salehpour M. The radiation exposure from portal images during the course of breast radiotherapy. Am J Clin Oncol 31(4):345-351, 2008. e-Pub 2008. PMID: 18845993.
26. Du W, Fan X, Foxley S, Zamora M, River JN, Culp RM, Karczmar GS. Comparison of high-resolution echo-planar spectroscopic imaging with conventional MR imaging of prostate tumors in mice. NMR Biomed 18:285-292, 2005. e-Pub 2005.
27. Du W, Karczmar GS, Uftring SJ, Du YP. Anatomical and functional brain imaging using high-resolution echo-planar spectroscopic imaging at 1.5 Tesla. NMR Biomed 18:235-241, 2005. e-Pub 2005.
28. Medved M, Newstead GM, Fan X, Du W, Du YP, MacEneaney PM, Culp RM, Kelcz F, Olopade OI, Zamora MA, Karczmar GS. Fourier components of inhomogeneously broadened water resonances in breast: a new source of MRI contrast. Magn Reson Med 52:193-196, 2004. e-Pub 2004.
29. Medved M, Du W, Zamora MA, Fan X, Olopade OI, MacEneaney PM, Newstead G, Karczmar GS. The effect of varying spectral resolution on the quality of high spectral and spatial resolution magnetic resonance images of the breast. J Magn Reson Imaging 18:442-448, 2003. e-Pub 2003.
30. Du W, Du YP, Fan X, Zamora MA, Karczmar GS. Reduction of spectral ghost artifacts in high-resolution echo-planar spectroscopic imaging of water and fat resonances. Magn Reson Med 49:1113-1120, 2003. e-Pub 2003.
31. Du W, Du YP, Bick U, Fan X, MacEneaney PM, Zamora MA, Medved M, Karczmar GS. Breast MR imaging with high spectral and spatial resolutions: preliminary experience. Radiology 224(2):577-585, 2002. e-Pub 2002. PMID: 12147859.
32. Du W, Karczmar GS, Pan X. Effects of constant frequency noise in magnetic resonance imaging with non-uniform k-space sampling. Med Phys 29:1832-1838, 2002. e-Pub 2002.
33. Karczmar GS, Du W, Medved M, Bick U, MacEneany P, Du YP, Fan X, Zamora M, Lipton M. Spectrally inhomogeneous effects of contrast agents in breast lesion detected by high spectral and spatial resolution MRI. Acad Radiol 9:S352-S354, 2002. e-Pub 2002.
34. Fan X, Du W, MacEneaney PM, Zamora M, Karczmar GS. Structure of the water resonance in small voxels in rat brain detected with high spectral and spatial resolution MRI. J Magn Reson Imaging 16:547-552, 2002. e-Pub 2002.

Professional Educational Materials

1. Du W, Baltz G, Slagowski J. Commissioning Report: ACB6 TrueBeam S/N: 4106, 2019.
2. Du W, Kudchadker R, Kerns J, Anand A, Kanke J. Volumetric modulated arc therapy: commissioning report, 2011.

Abstracts

1. Gao S, Du W, Cuthbert T, Zacharopoulos N, Balter P. Evaluation of IsoPoint system for coincidence of radiation and physical isocenter checks of linear accelerator. AAPM 67th Annual Meeting, 2025. e-Pub 2025.
2. Du W. Optimizing the collimator angles in radiation isocenter localization using Winston-Lutz tests. AAPM 67th Annual Meeting, 2025. e-Pub 2025.
3. Hassanzadeh CJ, Kuban DA, Pasyar S, Bassett R, Troncoso JP, Ansari MA, Schlembach PJ, McGuire SE, Nguyen QN, Frank SJ, Mok H, Mohamad O, Park RJH, Shah SJ, Mayo LL, Tang C, Du W, Kudchadker R, Choi S, Hoffman AK. Hypofractionated, Dose-Escalated Radiation vs. Conventionally Fractionated Radiation for Localized Prostate Cancer: Long-Term Update of a Phase 3, Prospective, Randomized Controlled Trial. ASTRO 2024 Annual Meeting, 2024. e-Pub 2024.
4. Chang E, Choi S, Fnu R, Tang C, Hassanzadeh CJ, Mohamad O, Frank SJ, Shah S, Mok H, Kudchadker R, Du W, Wang J, Yang J, Mayo L, Chronowski G, Hoffman K, McGuire S, Kuban DA, Nguyen QN. Stereotactic Body Radiotherapy for Prostate Cancer with Magnetic Resonance Imaging or Computed Tomography Guidance. ASTRO 2024 Annual Meeting, 2024. e-Pub 2024.
5. Gao S, Muruganandham M, Du W, Ohrt J, Kudchadker R, Balter PA. Customize electron energy beams on TrueBeam linacs. AAPM 63rd Annual Meeting, 2021. e-Pub 2021.
6. Wang L, Cao J, Lee H, Liu Z, Lin E, Ding Y, Wen Z, McDonald B, Vedam S, Martel M, Fuller C, Wang J, Krafft S, Du W, Tailor R, Ibbott G, Frank S. Preclinical in vivo human tumor response to magnetic resonance image-guided linear accelerator versus conventional linear accelerator. Int J Radiat Oncol Bio Phys 105(1):E657-E658, 2019. e-Pub 2019.
7. Du W, Gao S, Jiang W. Assessing the accuracy of IsoCal-calibrated image centers on Varian TrueBeam machines. AAPM 59th Annual Meeting, 2017. e-Pub 2017.
8. Choi S, Levy L, Lee KK, Nguyen QN, Lee AK, McGuire SE, Kudchaker RJ, Du W, Hoffman KE, Mahmood U, Frank SJ, Kuban DA. Identifying a subgroup of high-risk prostate cancer patients with worse clinical outcomes: should there be a “very high-risk” group?. Int J Radiat Oncol Biol Phys 96(2):E240-E241, 2016. e-Pub 2016.
9. Du W. Graphical user interface for digital Winston Lutz test-based localization of linac radiation isocenter and IGRT image centers. 2016 AAPM Spring Clinical Meeting, 2016. e-Pub 2016.
10. W, Cho SH, Zhang X, Hoffman KE, Kudchadker RJ. Decoding the beam complexity in intensity-modulated radiation therapy plans. Med Phys 41(6):305, 2014. e-Pub 2014.
11. Du W, Casey K, Kudchadker R. SU-E-T-134: Automated Analysis of Leaf Position Accuracy for Multi-Leaf Collimator Quality Assurance. Med Phys 40(6Part12):234, 2013. e-Pub 2013. PMID: 28519008.
12. Du W, Gao S, Wang X, Kudchadker R. SU-E-T-88: Evaluating Gantry Sag on Linear Accelerators and Introducing an MLC-Based Compensation Strategy. Med Phys 39(6Part11):3722-3723, 2012. e-Pub 2012. PMID: 28517157.
13. Yang M, Du W, Frank S, Pugh T, Bruno T, Kudchadker R. SU-E-T-260: Radiation Exposure Estimation for 131Cs Prostate Implant Patient Release Determination. Med Phys 39(6Part13):3763, 2012. e-Pub 2012. PMID: 28517343.
14. Wang X, Zhao Z, Du W, Li X, Yang J. SU-E-J-49: Reliability Study of ExacTrac- System Image Isocenter Using an On-Demand QA Procedure. Med Phys 39(6Part6):3663, 2012. e-Pub 2012. PMID: 28517561.
15. Anand A, Kerns J, Du W, Kudchadker R. A novel method using Agfa-Kodak-computer radiography system for routine quality assurance tests on linear accelerators. Med Phys 39(6):3718, 2012. e-Pub 2012.
16. Anand A, Du W, Chung H, Frank S, Pugh T, Kudchadker R. MD Anderson prostate seed implant dose calculator. Med Phys 39(6):3718, 2012. e-Pub 2012.
17. Gao S, Du W, Balter P. Evaluation of IsoCal imaging isocenter calibration system for Varian OBI machines. Med Phys 39(6):3604, 2012. e-Pub 2012.
18. Kudchadker RJ, Du W, Bruno TL, Pugh TJ, Frank SJ. Treatment planning dosimetry comparison between model 9011 I-125 ThinSeed and model 6711 I-125 seeds for prostate implant brachytherapy. Med Phys 38(6):3625, 2011. e-Pub 2011.
19. Luo D, Eley J, Du W, Shiu A, Chang E, Brown P, Newhauser W. Should treatment time be included in assessing the quality of a Gamma plan?. Med Phys 38(6):3543, 2011. e-Pub 2011.
20. Kudchadker R, Pugh T, Bruno T, Du W, Swanson D, Frank S. Optimizing quality assurance in a prospective phase II clinical trial for intermediate-risk prostate cancer with brachytherapy as monotherapy using a paladium-103 standed-seed nomogram. Med Phys 38(6):3625, 2011. e-Pub 2011.
21. Yang J, Du W, Li H, Luo D, McAleer MF, Martel MK, Gillin MT, Chang EL. Accurate spine SBRT setup with properly aligned MV and CBCT image systems. Med Phys 37(6):3311-3312, 2010. e-Pub 2010.
22. Wang X, Salepour M, Perkins GH, Tereffe W, Zhang SX, Du W, Sun TL, Strom EA, Buchholz TA, Yu TK. Setup variation in the supraclavicular lymph nodes treatment in cancer patients using on-board imaging system with linear accelerator. 92th Annual ARS Meeting, 2010. e-Pub 2010.
23. Du W, Yang JN, Chang EL, Luo D, McAleer MF, Shiu AS, Martel MK. Congruence of cone-beam CT image center with radiation isocenter of a linear accelerator. Med Phys 37(6):3162, 2010. e-Pub 2010.
24. Chi P, Du W, Yang J. Accurate determination of a linac radiation isocenter using iterative analysis of digitized star shot images. Med Phys 36(6):2586, 2009. e-Pub 2009.
25. Du W, Yang J, Luo D, Martel M. Computerized method for quantifying the alignment of mechanical or digital graticules relative to radiation fields using electronic portal images. Med Phys 36(6):2512, 2009. e-Pub 2009.
26. Palmer M, Banwo B, Georges R, Jones K, Lewis T, Du W, Mahajan A. Intensity Modulated Radiation Therapy Conformality Benchmarks for Regionally Specific Intracranial Lesions. Int J Radiat Oncol Biol Phys 72:S534, 2008. e-Pub 2008.
27. Du W, Yang J. A Robust Algorithm for Detecting Radiation Field Centers in Electronic Portal images with Subpixel Accuracy. Med Phys 35(6):2682, 2008. e-Pub 2008.
28. Wang X, Du W, Smith S, Buchholz T, Mohammad S. The radiation exposure to the contra-lateral breast from portal images during the course of breast radiotherapy. 49th Annual ASTRO Meeting, 2007. e-Pub 2007.
29. Du W, Lerma FA, Sakthi N, George R, Schaefer M, Bartee CL, Benedict SH. Determination of total scatter factors for stereotactic radiation fields by optimized fitting of readings from a small ion chamber and a mini-diode. 48th Annual AAPM Meeting, 2006. e-Pub 2006.
30. Lasio G, Williamson JF, Du W, Fatyga M. Spatial resolution-matched comparison between fan bema and cone beam x-ray CT images. 48th Annual AAPM Meeting, 2006. e-Pub 2006.
31. Lu L, Barani IJ, Cuttino L, Dogan N, Du W, Fatyga M, Siebers JV, Song S, Wu Y, Murphy MJ. Dosimetric consequences of inter-observer planning variability for head/neck radiotherapy. 48th Annual ASTRO Meeting:S449-S450, 2006. e-Pub 2006.
32. Lerma FA, Mihaylov IB, Du W, Benedict SH. Dosimetric Errors in Gated DMLC IMRT Delivery to a Moving Target with a 120-Leaf Collimator. Int J Radiat Oncol Biol Phys 63:S204, 2005. e-Pub 2005.
33. Taylor JL, Medved M, Du W, Newstead G, Karczmar GS. Corrections of B0 field inhomogeneities improves susceptibility-weighted breast echo planar spectroscopic images. 12th Annual ISMRS Meetings, 2004. e-Pub 2004.
34. Medved M, Newstead G, MacEneaney P, Du W, Zamora M, Fan X, Olopade O. Succeeful application of high spatial and spectral resolution MR for imaging of small breast lesions. 12th Annual ISMRM Meeting, 2004. e-Pub 2004.
35. Karczmar GS, Medved M, Du W, Fan X, Zamora M, MacEneaney, Du YP, Kelcz F, Newstead G. Images of the Fourier components of the water resonances in breast. 10th Annual ISMRM Meeting, 2003. e-Pub 2003.
36. Du W, Du YP, Bick U, Fan X, MacEneaney PM, Zamora MA, Medved M, Karczmar GS. Enhanced sensitivity to contrast agents: high spectral and spatial resolution MR imaging of the breast. 10th Annual ISMRM Meeting, 2002. e-Pub 2002.
37. Du W, Karczmar GS, Pan X. Constant frequency noise in magnetic resonance imaging with non-uniform k-space sampling - simulation study. 10th Annual ISMRM Meeting, 2002. e-Pub 2002.
38. Medved M, Du W, Zamora M, Fan X, Olopade F, MacEneaney PM, Bick U, Karczmar GS. The effect of varying spectral resolution on the quality of MR images of the breast. 10th Annual ISMRM Meeting, 2002. e-Pub 2002.
39. Medved M, Du W, Du YP, Bick U, Fan X, MacEneaney P, Zamora M, Karczmar GS. High resolution spatial and spectral imaging aids water-fat separation in breast imaging. 10th Annual ISMRM Meeting, 2002. e-Pub 2002.
40. Karczmar GS, Medved M, Du W, Zamora M, MacEneaney P, Olopade O. High spectral and spatial resolution MRI improves imaging of the breast. Department of Defense Breast Cancer Research Program Meeting, 2002. e-Pub 2002.
41. Cuthbert TA, Gao S, Du W, Zacharopoulos N, Balter P. Evaluation of the Isopoint System for Coincidence of Radiation and Physical Isocenter Checks of Linear Accelerators. AAPM 67th Annual Meeting.
42. Du W. Optimizing the collimator angles in radiation isocenter localization using Winston-Lutz tests. AAPM 67th Annual Meeting.