Xiande Liu, PHD

Peer-Reviewed Articles

1. German P, Bai S, Liu XD, Sun M, Zhou L, Kalra S, Zhang X, Minelli R, Scott KL, Mills GB, Jonasch E, Ding Z. Phosphorylation-dependent cleavage regulates von Hippel Lindau proteostasis and function. Oncogene 35(38):4973-80, 2016. e-Pub 2016. PMID: 26973240.
2. Zhou L, Liu XD, Sun M, Zhang X, German P, Bai S, Ding Z, Tannir N, Wood CG, Matin SF, Karam JA, Tamboli P, Sircar K, Rao P, Rankin EB, Laird DA, Hoang AG, Walker CL, Giaccia AJ, Jonasch E. Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma. Oncogene 35(21):2687-97, 2016. e-Pub 2015. PMID: 26364599.
3. DePavia A, Jonasch E, Liu XD. Autophagy degrades hypoxia inducible factors. Mol Cell Oncol 3(2):e1104428, 2016. e-Pub 2016. PMID: 27308629.
4. Xu G, Jiang Y, Xiao Y, Liu XD, Yue F, Li W, Li X, He Y, Jiang X, Huang H, Chen Q, Jonasch E, Liu L. Fast clearance of lipid droplets through MAP1S-activated autophagy suppresses clear cell renal cell carcinomas and promotes patient survival. Oncotarget 7(5):6255-65, 2016. PMID: 26701856.
5. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12(1):1-222, 2016. PMID: 26799652.
6. Liu X, Hoang A, Zhou L, Kalra S, Yetil A, Sun M, Ding Z, Zhang X, Bai S, German P, Tamboli P, Rao P, Karam JA, Wood CG, Matin SF, Zurita A, Bex A, Griffioen AW, Gao J, Sharma P, Tannir NM, Sircar K, Jonasch E. Resistance to anti-angiogenic therapy is associated with an immunosuppressive tumor microenvironment in metastatic renal cell carcinoma. Cancer Immunol Res. e-Pub 2015. PMID: 26014097.
7. Liu XD, Yao J, Tripathi DN, Ding Z, Xu Y, Sun M, Zhang J, Bai S, German P, Hoang A, Zhou L, Jonasch D, Zhang X, Conti CJ, Efstathiou E, Tannir NM, Eissa NT, Mills GB, Walker CL, Jonasch E. Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis. Oncogene 34(19):2450-60, 2015. e-Pub 2014. PMID: 24998849.
8. Ho TH, Liu XD, Huang Y, Warneke CL, Johnson MM, Hoang A, Tamboli P, Wang F, Jonasch E. The impact of FGFR1 and FRS2α expression on sorafenib treatment in metastatic renal cell carcinoma. BMC Cancer 15:304, 2015. e-Pub 2015. PMID: 25900027.
9. Zhou X, Wang Y, Shan B, Han J, Zhu H, Lv Y, Fan X, Sang M, Liu XD, Liu W. The downregulation of miR-200c/141 promotes ZEB1/2 expression and gastric cancer progression. Med Oncol 32(1):428, 2015. e-Pub 2014. PMID: 25502084.
10. Ding Z, German P, Bai S, Reddy AS, Liu XD, Sun M, Zhou L, Chen X, Zhao X, Wu C, Zhang S, Mills GB, Jonasch E. Genetic and pharmacological strategies to refunctionalize the von Hippel Lindau R167Q mutant protein. Cancer Research 74:3127-36, 2014.
11. Chen W, Ayala-Orozco C, Biswal NC, Perez-Torres C, Bartels M, Bardhan R, Stinnet G, Liu XD, Ji B, Deorukhkar A, Brown LV, Guha S, Pautler RG, Krishnan S, Halas NJ, Joshi A. Targeting pancreatic cancer with magneto-fluorescent theranostic gold nanoshells. Nanomedicine (Lond) 9(8):1209-22, 2014. e-Pub 2013. PMID: 24063415.
12. Deeraksa A, Pan J, Sha Y, Liu XD, Eissa NT, Lin SH, Yu-Lee LY. Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis. Oncogene 32(24):2973-83, 2013. e-Pub 2012. PMID: 22890325.
13. Xu Y, Fattaha EA, Liu XD, Jagannath C, Eissaa NT. Harnessing of TLR-mediated autophagy to combat mycobacteria in macrophages. Tuberculosis:S33-S37, 2013.
14. Liu XD, Ko S, Xu Y, Fattah EA, Xiang Q, Jagannath C, Ishii T, Komatsu M, Eissa NT. Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress. J Biol Chem 287(23):19687-98, 2012. e-Pub 2012. PMID: 22518844.
15. Liu XD, Mazumdar T, Xu Y, Getzoff ED, Eissa NT. Identification of a flavin mononucleotide module residue critical for activity of inducible nitrite oxide synthase. J Immunol 183(9):5977-82, 2009. e-Pub 2009. PMID: 19828635.
16. Xu Y, Liu XD, Gong X, Eissa NT. Signaling pathway of autophagy associated with innate immunity. Autophagy 4(1):110-2, 2008. e-Pub 2007. PMID: 18059159.
17. Xu Y, Jagannath C, Liu XD, Sharafkhaneh A, Kolodziejska KE, Eissa NT. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity 27(1):135-44, 2007. e-Pub 2007. PMID: 17658277.
18. Liu X, Shen Y. Salt shock induces state II transition of the photosynthetic apparatus in dark-adapted Dunaliella salina cells. Environmental and Experimental Botany 57(1–2):19-24, 2006.
19. Liu XD, Ma WM, Shen YG. State transition of the photosynthetic apparatus in plant. Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao 32(2):127-32, 2006. PMID: 16622310.
20. Liu XD, Hu FH, Shen YG. Transient decrease of light-harvesting complex II phosphorylation level by hypoosmotic shock in dark-adapted Dunaliella salina. Acta Biochim Biophys Sin (Shanghai) 38(2):104-9, 2006. PMID: 16474901.
21. Liu XD, Shen YG. Changes in trans-thylakoid membrane proton motive force induced by treatments with red and far-red light in Dunaliella salina. Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao 31(3):317-21, 2005. PMID: 15961908.
22. Liu XD, Shen YG. Salt-induced redox-independent phosphorylation of light harvesting chlorophyll a/b proteins in Dunaliella salina thylakoid membranes. Biochim Biophys Acta 1706(3):215-9, 2005. PMID: 15694349.
23. Liu XD, Shen YG. NaCl-induced phosphorylation of light harvesting chlorophyll a/b proteins in thylakoid membranes from the halotolerant green alga, Dunaliella salina. FEBS Lett 569(1-3):337-40, 2004. PMID: 15225658.
24. Liu X, Shen Y. Hypoosmotic shock induces a stateⅠtransition of photosynthetic apparatus in Dunaliella salina. Chinese Science Bulletin Vol. 49(No. 7):672—675, 2004.

Invited Articles

1. Liu XD, Zhu H, DePavia A, Jonasch E. Dysregulation of HIF2a and autophagy in renal cell carcinoma. Molecular & Cellular Oncology 2(2):e965643, 2014.

Abstracts

1. Liu X, Hoang A, Zhou L, Kalra S, Yetil A, Sun M, Ding Z, Tamboli P, Rao P, Karam JA, Wood CG, Matin SF, Zurita AJ, Bex A, Griffioen AW, Gao J, Sharma P, Tannir NM, Sircar K, Jonasch E. Resistance to anti-angiogenic therapy is associated with an immunosuppressive tumor microenvironment in metastatic renal cell carcinoma. 2015 Genitourinary Cancers Symposium, 2015.
2. Liu XD, Hoang A, Zhou L, Kalra S, Yetil A, Sun M, Ding Z, Bai S, German P, Zhang X, Tamboli P, Rao P, Karam J, Wood C, Matin S, Zurita A, Bex A, Griffioen AW, Tannir N, Sircar K, Jonasch E. Anti-angiogenic therapy induces T-lymphocyte infiltration associated with poor survival in metastatic renal cell carcinoma patients. 26th EORTC-NCI-AACR symposium on Molecular Targets and Cancer Therapeutics, 2014.
3. Xu Y, Liu X, Eissa T. Harnessing Of TLR-mediated Autophagy To Eliminate Mycobacterium Tuberculosis From Macrophages. American Thoracic Society, 2010.
4. Liu XD, Xu Y, Fung C, Dalu Z, Xiang Q, Jagannath C, Eissa NT. BCG Infection Induces P62-Dependent Autophagy-Independent Formation Of Dendritic Cell Aggresome-Like Structures. Am J Respir Crit Care Med. e-Pub 2010.
5. Liu XD, Ko S, Xiang Q, Eissa TN. Alis Formation Is A Cytosolic Unfolded Protein Response To Inflammation And Endoplasmic Reticulum Stress. Am J Respir Crit Care Med. e-Pub 2010.