David E. Ost, M.D., M.P.H., F.A.C.P.
Department of Pulmonary Medicine, Division of Internal Medicine
Present Title & Affiliation
Primary Appointment
Professor, Department of Pulmonary Medicine, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Research Interests
My long-term goal is to understand the factors that contribute to pulmonary morbidity and mortality in cancer patients in order to develop more cost-effective treatments and interventions. My particular area of focus is interventional pulmonology. Areas of interest include diagnosis and staging of lung cancer using endobronchial ultrasound, comparative effectiveness of bronchial stenting, impact of bronchoscopic interventions on quality adjusted survival, and impact of indwelling pleural catheters on quality adjusted survival and health care resource utilization.
Education & Training
Degree-Granting Education
2005 | Harvard School of Public Health, Boston, MA, USA, MPH, Masters of Public Health |
1990 | Thomas Jefferson University Medical College, Philadelphia, PA, USA, MD, Medicine |
1986 | Pennsylvania State University, University Park, PA, USA, BS, Science |
Board Certifications
1997 | American Board of Internal Medicine, Subspecialty Critical Care |
1996 | American Board of Internal Medicine, Subspecialty Pulmonary |
1993 | American Board of Internal Medicine |
Experience & Service
Administrative Appointments/Responsibilities
Director of Clinical Research, Department of Pulmonary Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 2010 - 2017
Honors & Awards
2006 | Alfred Sofer Award, American College of Chest Physicians |
Professional Memberships
Selected Publications
Peer-Reviewed Articles
- Gonzalez AV, Ost DE, Shojaee S. Diagnostic Accuracy of Bronchoscopy Procedures: Definitions, Pearls, and Pitfalls. J Bronchology Interv Pulmonol 29(4):290-299, 2022. e-Pub 2022. PMID: 36066281.
- Steinfort DP, Siva S, Rangamuwa K, Lee P, Fielding D, Nguyen P, Jennings BR, Yo S, Hardcastle N, Kothari G, Crombag L, Annema J, Yasufuku K, Ost DE, Irving LB. Systematic endoscopic staging of mediastinum to determine impact on radiotherapy for locally advanced lung cancer (SEISMIC): protocol for a prospective single arm multicentre interventional study. BMC Pulm Med 22(1):364, 2022. e-Pub 2022. PMID: 36153502.
- Salahuddin M, Sarkiss M, Sagar AS, Vlahos I, Chang CH, Shah A, Sabath BF, Lin J, Song J, Moon T, Norman PH, Eapen GA, Grosu HB, Ost DE, Jimenez CA, Chintalapani G, Casal RF. "Ventilatory Strategy to Prevent Atelectasis During Bronchoscopy Under General Anesthesia: A Multicenter Randomized Controlled Trial" (VESPA Trial). Chest. e-Pub 2022. PMID: 35803302.
- Sheshadri A, Makhnoon S, Alousi AM, Bashoura L, Andrade R, Miller CJ, Stolar KR, Arain MH, Noor L, Balagani A, Jain A, Blanco D, Ortiz A, Taylor MS, Stenzler A, Mehta R, Popat UR, Hosing C, Ost DE, Champlin RE, Dickey BF, Peterson SK. Home-Based Spirometry Telemonitoring After Allogeneic Hematopoietic Cell Transplantation: Mixed Methods Evaluation of Acceptability and Usability. JMIR Form Res 6(2):e29393, 2022. e-Pub 2022. PMID: 35129455.
- Grosu HB, Kern R, Maldonado F, Casal R, Andersen CR, Li L, Eapen G, Ost D, Jimenez C, Frangopoulos F, Sabath B, Vakil E, Schwalk A, Marcoux M, Sagar AE, Nasim F, Lin J, Salahudin M, Arain HM, Noor L, Montanez D, Stewart J, Mullon J, Michael M, Porfyridis I. Predicting malignant pleural effusion during diagnostic pleuroscopy with biopsy: A prospective multicentre study. Respirology. e-Pub 2022. PMID: 35178828.
- Ost DE. Interpretation and Application of the Likelihood Ratio to Clinical Practice in Thoracic Oncology. J Bronchology Interv Pulmonol 29(1):62-70, 2022. e-Pub 2021. PMID: 34162800.
- Simoff MJ, Pritchett MA, Reisenauer JS, Ost DE, Majid A, Keyes C, Casal RF, Parikh MS, Diaz-Mendoza J, Fernandez-Bussy S, Folch EE. Shape-sensing robotic-assisted bronchoscopy for pulmonary nodules: initial multicenter experience using the Ion™ Endoluminal System. BMC Pulm Med 21(1):322, 2021. e-Pub 2021. PMID: 34656103.
- Reisenauer J, Simoff MJ, Pritchett MA, Ost DE, Majid A, Keyes C, Casal RF, Parikh MS, Diaz-Mendoza J, Fernandez-Bussy S, Folch EE. Ion: technology and techniques for shape-sensing robotic-assisted bronchoscopy. Ann Thorac Surg. 2022; 113(1):308-15. e-Pub 2021. PMID: 34370981.
- Sainz Zuniga PV, Ost DE. Impact of Delays in Lung Cancer Treatment on Survival. Chest 2021; 160(5):1934-58. e-Pub 2021. PMID: 34425080.
- Vakil E, Jackson N, Sainz-Zuñega PV, Molina S, Martinez-Zayas G, Cantor SB, Grosu HB, Casal RF, Ost DE. Optimizing diagnostic and staging pathways for suspected lung cancer: a decision analysis. Chest 2021; 160(6):2304-23. e-Pub 2021. PMID: 34256049.
- Molina S, Martinez-Zayas G, Sainz PV, Leung CH, Li L, Grosu HB, Adachi R, Ost DE. BLESS models: Improving Survival Prediction in Patients with Malignant Pleural Effusion and Metastasis. Chest 160(3):1075-1094. e-Pub 2021. PMID: 33852918.
- Wilshire CL, Chang SC, Gilbert CR, Akulian JA, AlSarraj MK, Asciak R, Bevill BT, Davidson KR, Delgado A, Grosu HB, Herth FJF, Lee HJ, Lewis JE, Maldonado F, Ost DE, Pastis NJ, Rahman NM, Reddy CB, Roller LJ, Sanchez TM, Shojaee S, Steer H, Thiboutot J, Wahidi MM, Wright AN, Yarmus LB, Gorden JA. Association between Tunneled Pleural Catheter Use and Infection in Patients Immunosuppressed from Antineoplastic Therapy. A Multicenter Study. Ann Am Thorac Soc 18(4):606-612, 2021. PMID: 33026887.
- Sainz Zúñiga PV, Martinez-Zayas G, Molina S, Grosu HB, Arain MH, Ost DE. Is Biopsy of Contralateral Hilar N3 Lymph Nodes With Negative PET-CT Scan Findings Necessary When Performing Endobronchial Ultrasound Staging?. Chest 2021; 159(4):1642-51. e-Pub 2021. PMID: 33393471.
- Martinez-Zayas G, Almeida FA, Yarmus L, Steinfort D, Lazarus DR, Simoff MJ, Saettele T, Murgu S, Dammad T, Duong DK, Mudambi L, Filner JJ, Molina S, Aravena C, Thiboutot J, Bonney A, Rueda AM, Debiane LG, Hogarth DK, Bedi H, Deffebach M, Sagar AS, Cicenia J, Yu DH, Cohen A, Frye L, Grosu HB, Gildea T, Feller-Kopman D, Casal RF, Machuzak M, Arain MH, Sethi S, Eapen GA, Lam L, Jimenez CA, Ribeiro M, Noor LZ, Mehta A, Song J, Choi H, Ma J, Li L, Ost DE. Predicting Lymph Node Metastasis in Non-Small Cell Lung Cancer: Prospective External and Temporal Validation of the HAL and HOMER Models. Chest 160(3):1108-1120. e-Pub 2021. PMID: 33932466.
- Zhang Y, Simoff MJ, Ost D, Wagner OJ, Lavin J, Nauman B, Hsieh MC, Wu XC, Pettiford B, Shi L. Understanding the patient journey to diagnosis of lung cancer. BMC Cancer 21(1):402, 2021. e-Pub 2021. PMID: 33853552.
- Schwalk AJ, Ost DE, Saltijeral SN, De La Garza H, Casal RF, Jimenez CA, Eapen GA, Lewis J, Rinsurongkawong W, Rinsurongkawong V, Lee J, Elamin Y, Zhang J, Roth JA, Swisher S, Heymach JV, Grosu HB. Risk Factors for and Time to Recurrence of Symptomatic Malignant Pleural Effusion in Patients with Metastatic Non-Small Cell Lung Cancer with EGFR or ALK Mutations. Chest 159(3):1256-1264, 2021. e-Pub 2020. PMID: 33217413.
- Chiu YW, Kao YH, Simoff MJ, Ost DE, Wagner O, Lavin J, Culbertson RA, Smith DG. Costs of Biopsy and Complications in Patients with Lung Cancer. Clinicoecon Outcomes Res 13:191-200, 2021. e-Pub 2021. PMID: 33762834.
- Sagar AS, Sabath BF, Eapen GA, Song J, Marcoux M, Sarkiss M, Arain MH, Grosu HB, Ost DE, Jimenez CA, Casal RF. Incidence and Location of Atelectasis Developed During Bronchoscopy Under General Anesthesia: The I-LOCATE Trial. Chest 158(6):2658-2666, 2020. e-Pub 2020. PMID: 32561439.
- Datar S, Cabanillas M, Dadu R, Ost D, Grosu HB. Pulmonary cavitation in patients with thyroid cancer receiving antiangiogenic agents. BMC Cancer 20(1):1181, 2020. e-Pub 2020. PMID: 33267782.
- Wilshire CL, Chang SC, Gilbert CR, Akulian JA, AlSarraj MK, Asciak R, Bevill BT, Davidson KR, Delgado A, Grosu HB, Herth FJ, Lee HJ, Lewis JE, Maldonado F, Ost DE, Pastis NJ, Rahman NM, Reddy CB, Roller LJ, Sanchez TM, Shojaee S, Steer H, Thiboutot J, Wahidi MM, Wright AN, Yarmus LB, Gorden JA. Temporal trends in tunneled pleural catheter utilization in patients with malignancy: A multicenter review. Chest 2021; 159(6):2483-7. e-Pub 2020. PMID: 33307064.
- Zhao H, Xu Y, Huo J, Burks AC, Ost DE, Shih YT. Updated Analysis of Complication Rates Associated With Invasive Diagnostic Procedures After Lung Cancer Screening. JAMA Netw Open 3(12):e2029874, 2020. e-Pub 2020. PMID: 33326023.
- Vial MR, Nasim F, La Garza H, Ost DE, Casal RF, Eapen GA, Jimenez C, Grosu HB. Endobronchial ultrasound- guided transbronchial needle aspiration for mediastinal lymph node staging in patients with typical pulmonary carcinoids. Lung Cancer 147:198-203, 2020. e-Pub 2020. PMID: 32736278.
- Wahidi MM, Shojaee S, Lamb CR, Ost D, Maldonado F, Eapen G, Caroff DA, Stevens MP, Ouellette DR, Lilly C, Gardner DD, Glisinski K, Pennington K, Alalawi R. The Use of Bronchoscopy During the Coronavirus Disease 2019 Pandemic: CHEST/AABIP Guideline and Expert Panel Report. Chest 158(3):1268-1281, 2020. e-Pub 2020. PMID: 32361152.
- Sheshadri A, Alousi A, Bashoura L, Stolar K, Baghaie S, Arain MH, Noor L, Balagani A, Jain A, Blanco D, Ortiz A, Peterson SK, Langhals R, Taylor M, Stenzler A, Mehta RS, Popat UR, Hosing C, Rondon G, Shen F, Li L, Cheng GS, Ost DE, Champlin RE, Dickey BF. Feasibility and Reliability of Home-based Spirometry Telemonitoring in Allogeneic Hematopoietic Cell Transplant Recipients. Ann Am Thorac Soc. e-Pub 2020. PMID: 32614241.
- Sagar AES, Landaeta MF, Adrianza AM, Aldana GL, Pozo L, Armas-Villalba A, Toquica CC, Larson AJ, Vial MR, Grosu HB, Ost DE, Eapen GA, Sheshadri A, Morice RC, Shannon VR, Bashoura L, Balachandran DD, Almeida FA, Uzbeck MH, Casal RF, Faiz SA, Jimenez CA. Complications following symptom limited thoracentesis using suction. Eur Respir J. e-Pub 2020. PMID: 32499336.
- Gilbert CR, Wahidi MM, Light RW, Rivera MP, Sterman DH, Thomas R, Shojaee S, Shoham S, Psallidas I, Ost DE, Molena D, Maskell N, Maldonado F, Liberman M, Lee YCG, Lee H, Herth FJF, Grosu H, Gorden JA, Fysh ETH, Corcoran JP, Argento AC, Akulian JA, Rahman NM, Yarmus LB, Interventional Pulmonary Outcomes Group. Management of Indwelling Tunneled Pleural Catheters: A Modified Delphi Consensus Statement. Chest. e-Pub 2020. PMID: 32561437.
- Ost DE, Niu J, Zhao H, Grosu HB, Giordano SH. Quality Gaps and Comparative Effectiveness in Lung Cancer Staging and Diagnosis. Chest 157(5):1322-1345, 2020. e-Pub 2019. PMID: 31610159.
- Goldblatt DL, Flores JR, Valverde Ha G, Jaramillo AM, Tkachman S, Kirkpatrick CT, Wali S, Hernandez B, Ost DE, Scott BL, Chen J, Evans SE, Tuvim MJ, Dickey BF. Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice. Br J Pharmacol 177(10):2256-2273, 2020. e-Pub 2020. PMID: 31968123.
- Leisman DE, Harhay MO, Lederer DJ, Abramson M, Adjei AA, Bakker J, Ballas ZK, Barreiro E, Bell SC, Bellomo R, Bernstein JA, Branson RD, Brusasco V, Chalmers JD, Chokroverty S, Citerio G, Collop NA, Cooke CR, Crapo JD, Donaldson G, Fitzgerald DA, Grainger E, Hale L, Herth FJ, Kochanek PM, Marks G, Moorman JR, Ost DE, Schatz M, Sheikh A, Smyth AR, Stewart I, Stewart PW, Swenson ER, Szymusiak R, Teboul JL, Vincent JL, Wedzicha JA, Maslove DM. Development and Reporting of Prediction Models: Guidance for Authors From Editors of Respiratory, Sleep, and Critical Care Journals. Crit Care Med 48(5):623-633, 2020. PMID: 32141923.
- Sainz Zuñiga PV, Vakil E, Molina S, Bassett RL, Ost DE. Sensitivity of Radial Endobronchial Ultrasound-Guided Bronchoscopy for Lung Cancer in Patients With Peripheral Pulmonary Lesions: An Updated Meta-analysis. Chest 157(4):994-1011, 2020. e-Pub 2019. PMID: 31738928.
- Grosu HB, Manzanera A, Shivakumar S, Sun S, Noguras Gonzalez G, Ost DE. Survival Disparities Following Surgery Among Patients with Different Histological Types of Non-small Cell Lung Cancer. Lung Cancer 140:55-58, 2020. e-Pub 2019. PMID: 31865279.
- Bailey M, Eapen G, Ost D, Casal RF, Jimenez C, Datar S, Molina S, Bashoura L, Faiz SA, Balachandran DD, Shannon VR, Sheshadri A, Grosu HB. Routine Microbiologic Studies of Pleural Fluid Specimens in Cancer Patients. Am J Med 133(2):240-244, 2020. e-Pub 2019. PMID: 31401163.
- Grosu HB, Lu W, Ost DE, Vial MR, Hernandez M, Ghosh N, Noor L, Hasan AM, Bashoura L, Faiz S, Balachandran D, Casal R, Eapen G, Shannon V, Sheshadri A, Tang X, Rahman N, Wistuba II. Pleural Fluid Cytokine Levels at Baseline and Over Time are Associated With Time to IPC Removal: An Exploratory Study. J Bronchology Interv Pulmonol 27(1):4-13, 2020. e-Pub 2019. PMID: 31373905.
- Martinez-Zayas G, Almeida FA, Simoff MJ, Yarmus L, Molina S, Young B, Feller-Kopman D, Sagar AS, Gildea T, Debiane LG, Grosu HB, Casal RF, Arain MH, Eapen GA, Jimenez CA, Noor LZ, Baghaie S, Song J, Li L, Ost DE. A Prediction Model to Help with Oncologic Mediastinal Evaluation for Radiation: HOMER. Am J Respir Crit Care Med 201(2):212-223, 2020. PMID: 31574238.
- Sagar AS, Eapen GA, Casal RF, Ost D, Sarkiss M, Grosu HB. Safety of Pleuroscopy Performed in Negative Pressure Bronchoscopy Rooms. J Bronchology Interv Pulmonol 26(4):250-253, 2019. e-Pub 2018. PMID: 30543551.
- Herman DD, Thomson CC, Brosnhan S, Patel R, Trosini-Desert V, Bilaceroglu S, Poston JT, Liberman M, Shah PL, Ost DE, Chatterjee R, Michaud GC.. Risk of Bleeding in Patients Undergoing Pulmonary Procedures on Antiplatelet or Anticoagulants: A Systematic Review. Respir Med(153):76-84, 2019.
- Grosu HB, Arriola A, Stewart J, Ma J, Bassett R, Hernandez M, Ost D, Roy-Chowdhuri S. PD-L1 Detection in Histology Specimens and Matched Pleural Fluid Cell Blocks of Patients with NSCLC. Respirology. e-Pub 2019. PMID: 31209954.
- Casal RF, Sepesi B, Sagar AS, Tschirren J, Chen M, Li L, Sunny J, Williams J, Grosu HB, Eapen GA, Jimenez CA, Ost DE.. Centrally Located Lung Cancer and Risk of Occult Nodal Disease: An Objective Evaluation of Multiple Definitions of Tumour Centrality with Dedicated Imaging Software. Eur Respir J 53:5, 2019. e-Pub 2019.
- Debiane L, Reitzel R, Rosenblatt J, Gagea M, Chavez MA, Adachi R, Grosu HB, Sheshadri A, Hill LR, Raad I, Ost DE.. A Design-Based Stereologic Method to Quantify the Tissue Changes Associated with a Novel Drug-Eluting Tracheobronchial Stent. Respiration(98 (1)):60-69. e-Pub 2019.
- Grosu HB, Molina S, Casal R, Song J, Li L, Diaz-Mendoza J, Reddy C, Yarmus L, Schiavo D, Simoff M, Johnstun J, Raid AA, Feller-Kopman D, Lee H, Sahetya S, Foley F, Maldonado F, Tian X, Noor L, Miller R, Mudambi L, Saettele T, Vial-Rodriguez M, Eapen GA, Ost DE. Risk Factors for Pleural Effusion Recurrence in Patients with Malignancy. Respirology 23:76-82, 2019. e-Pub 2018. PMID: 29966171.
- Ong P, Grosu HB, Debiane L, Casal RF, Eapen GA, Jimenez CA, Noor L, Ost DE. Long-term Quality-adjusted Survival Following Therapeutic Bronchoscopy for Malignant Central Airway Obstruction. Thorax 74:141-156, 2019. e-Pub 2018. PMID: 30254139.
- Lederer DJ, Bell SC, Branson RD, Chalmers JD, Marshall R, Maslove DM, Ost DE, Punjabi NM, Schatz M, Smyth AR, Stewart PW, Suissa S, Adjei AA, Akdis CA, Azoulay É, Bakker J, Ballas ZK, Bardin PG, Barreiro E, Bellomo R, Bernstein JA, Brusasco V, Buchman TG, Chokroverty S, Collop NA, Crapo JD, Fitzgerald DA, Hale L, Hart N, Herth FJ, Iwashyna TJ, Jenkins G, Kolb M, Marks GB, Mazzone P, Moorman JR, Murphy TM, Noah TL, Reynolds P, Riemann D, Russell RE, Sheikh A, Sotgiu G, Swenson ER, Szczesniak R, Szymusiak R, Teboul JL, Vincent JL.. Control of Confounding and Reporting of Results in Causal Inference Studies. Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals. Ann Am Thorac Soc 16(1):22-28, 2019. PMID: 30230362.
- Mahajan AK, Ost DE, Cole BF, Kinsey CM. Applications of Noninferiority Trials in Interventional Pulmonology. J Bronchology Interv Pulmonol 26(1):6-9, 2019. PMID: 30562280.
- Mahajan AK, Ost DE, Cole BF, Kinsey CM. Applications of Noninferiority Trials in Interventional Pulmonology. J Bronchology Interv Pulmonol 26(1):6-9, 2019.
- Grosu HB, Vial MR, Hernandez M, Li L, Casal RF, Eapen GA, Ost DE. Secondary Spontaneous Pneumothorax in Cancer Patients. Journal of Thoracic Disease 11(4):1495-1505, 2019.
- Sheshadri A, Karimipour M, Vakil E, Bashoura L, Godoy M, Arain MH, Evans SE, Dickey BF, Ost DE, Chemaly RF, Faiz SA.. Refinement of Estimates of Mortality Risk Using the Radiologic Severity Index in Hematologic Malignancy Patients with Respiratory Syncytial Virus Infection. Transplant Infectious Disease: An Official Journal of the Transplantation Society:e13105, 2019. e-Pub 2019.
- Sabath B, Muhammad HA, Balagani A, Ost DE, Vakil E, Ahmed T, Vial MR, Grosu HB. Secondary Spontaneous Pneumothorax in Patients with Sarcoma Treated with Pazopanib, a Case Control Study. BMC Cancer 18(1):937, 2018. e-Pub 2018. PMID: 30285733.
- Ahmed T, Vial MR, Ost D, Stewart J, Hasan MA, Grosu HB. Non-small Cell Lung Cancer Transdifferentiation into Small Cell Lung Cancer: A Case Series. Lung Cancer 122:220-223, 2018. e-Pub 2018. PMID: 30032836.
- Ost DE, Niu J, Zhao H, Grosu HB, Giordano SH. Quality Gaps and Comparative Effectiveness of Management Strategies for Recurrent Malignant Pleural Effusions. Chest 153(2):438-452, 2018. e-Pub 2017. PMID: 28864054.
- Vakil E, Ost D, Vial MR, Stewart J, Sarkiss MG, Morice RC, Casal RF, Eapen GA, Grosu HB. Non-specific Pleuritis in Patients with Active Malignancy. Respirology 23(2):213-219, 2018. e-Pub 2017. PMID: 29024191.
- Vakil E, Sarkiss M, Ost D, Vial MR, Casal RF, Eapen GA, Grosu HB. Safety of Monitored Anesthesia Care Using Propofol-Based Sedation for Pleuroscopy. Respiration 95(1):1-7, 2018. e-Pub 2017. PMID: 28918427.
- Vial MR, O'Connell OJ, Grosu HB, Hernandez M, Noor L, Casal RF, Stewart J, Sarkiss M, Jimenez CA, Rice D, Mehran R, Ost DE, Eapen GA. Diagnostic Performance of Endobronchial Ultrasound-guided Mediastinal Lymph Node Sampling in Early Stage Non-small Cell Lung Cancer: A Prospective Study. Respirology 23(1):76-81, 2018. e-Pub 2017. PMID: 28857362.
- Sheshadri A, Shah DP, Godoy M, Erasmus JJ, Song J, Li L, Evans SE, Chemaly RF, Dickey BF, Ost DE. Progression of the Radiologic Severity Index Predicts Mortality in Patients with Parainfluenza Virus-associated Lower Respiratory Infections. PLoS One 13(5):e0197418, 2018. e-Pub 2018. PMID: 29771962.
- Vial MR, Eapen GA, Casal RF, Sarkiss MG, Ost DE, Vakil E, Grosu HB. Combined Pleuroscopy and Endobronchial Ultrasound for Diagnosis and Staging of Suspected Lung Cancer. Respir Med Case Rep 23:49-51, 2018. e-Pub 2017. PMID: 29276672.
- Casal RF, Walsh G, McArthur M, Hill LR, Landaeta MF, Armas Villalba AJ, Ong P, Debiane L, Vakil E, Grosu HB, Jimenez CA, Ost D, Adachi R, Eapen GA. Bronchoscopic Laser Interstitial Thermal Therapy: An Experimental Study in Normal Porcine Lung Parenchyma. J Bronchology Interv Pulmonol 25:322-329, 2018. e-Pub 2018. PMID: 29771774.
- Grosu HB, Kazzaz F, Vakil E, Molina S, Ost D. Sensitivity of Initial Thoracentesis for Malignant Pleural Effusion Stratified by Tumor Type in Patients with Strong Evidence of Metastatic Disease. Respiration 96:363-369, 2018. e-Pub 2018. PMID: 30016797.
- Ontiveros N, Eapen-John D, Osorio N, Song J, Li L, Sheshadri A, Tiang X, Ghosh N, Vaporciyan A, Correa A, Walsh G, Grosu HB, Ost DE. Predicting Lung Function Following Lobectomy: A New Method to Adjust for Inherent Selection Bias. Respiration 96(5):434-445, 2018. e-Pub 2018. PMID: 30257257.
- Grosu HB, Ost DE, Lee YI, Song J, Li L, Eden E, Rose K. Diaphragm Muscle Thinning in Subjects Receiving Mechanical Ventilation and Its Effect on Extubation. Respir Care 62(7):904-911, 2017. e-Pub 2017. PMID: 28351903.
- O'Connell OJ, Almeida FA, Simoff MJ, Yarmus L, Lazarus R, Young B, Chen Y, Semaan R, Saettele TM, Cicenia J, Bedi H, Kliment C, Li L, Sethi S, Diaz-Mendoza J, Feller-Kopman D, Song J, Gildea T, Lee H, Grosu HB, Machuzak M, Rodriguez-Vial M, Eapen GA, Jimenez CA, Casal RF, Ost DE. A Prediction Model to Help with the Assessment of Adenopathy in Lung Cancer (HAL). Am J Respir Crit Care Med 195(12):1651-1660, 2017. e-Pub 2016. PMID: 28002683.
- Faiz SA, Pathania P, Song J, Li L, Balachandran DD, Ost DE, Morice RC, Shannon VR, Bashoura L, Eapen GA, Jimenez CA. Indwelling Pleural Catheters for Patients with Hematologic Malignancies: A 14-Year, Single-Center Experience. Ann Am Thorac Soc 14:976-985. e-Pub 2017. PMID: 28326798.
- Casal RF, Vial MR, Miller R, Mudambi L, Grosu HB, Eapen GA, Jimenez CA, Morice RC, Cornwell L, Ost D. What Exactly is a Centrally Located Lung Tumor? Results of an On-line Survey. Ann Am Thorac Soc 14:118-23, 2017. e-Pub 2016. PMID: 27854541.
- Vial MR, Khan KA, O'Connell O, Peng SA, Gomez DR, Chang JY, Rice DC, Mehran R, Jimenez CJ, Grosu HB, Ost DE, Eapen GA. Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in the Nodal Staging of Stereotactic Ablative Body Radiotherapy Patients. Ann Thorac Surg 103:16000-1605, 2017. e-Pub 2016. PMID: 28027732.
- Grosu HB, Vial MR, Vakil E, Casal RF, Eapen GA, Morice R, Stewart J, Sarkiss MG, Ost DE. Pleural Touch Preparations and Direct Visualization of the Pleura During Medical Thoracoscopy for the Diagnosis of Malignancy. Ann Am Thorac Soc 14:1326-1331, 2017. e-Pub 2017. PMID: 28406718.
- Vakil E, Ost D, Vial MR, Stewart J, Sarkiss MG, Morice RC, Casal RF, Eapen GA, Grosu HB. Non-specific Pleuritic in Patients with Active Malignancy. Respirology, 2017.
- Vial MR, Stewart J, Lazarus DR, Eapen GA, Ost DE, Grosu HB, Jimenez CA. Unusual Aetiology of a Hilar Mass in a Man with History of Thyroid Cancer. Thorax. e-Pub 2016. PMID: 27422794.
- Vial MR, Ost DE, Eapen GA, Jimenez CA, Morice RC, O'Connell O, Grosu HB. Intrapleural Fibrinolytic Therapy in Patients with Nondraining Indwelling Pleural Catheters. J Bronchology Interv Pulmonol 23(2):98-105, 2016. PMID: 27058711.
- Ost DE, Ernst A, Lei X, Kovitz KL, Benzaquen S, Diaz-Mendoza J, Greenhill S, Toth J, Feller-Kopman D, Puchalski J, Baram D, Karunakara R, Jimenez CA, Filner JJ, Morice RC, Eapen GA, Michaud GC, Estrada-Y-Martin RM, Rafeq S, Grosu HB, Ray C, Gilbert CR, Yarmus LB, Simoff M, AQuIRE Bronchoscopy Registry. Diagnostic Yield and Complications of Bronchoscopy for Peripheral Lung Lesions: Results of the AQuIRE Registry. Am J Respir Crit Care Med 193(1):68-77, 2016. e-Pub 2015. PMID: 26367186.
- Vial MR, O'Connell JO, Grosu HB, Ost DE, Eapen GA, Jimenez CA. Needle Fracture During Endobronchial Ultrasound-guided Transbronchial Needle Aspiration. Am J Respir Crit Care Med 193(2):213-4, 2016. PMID: 26378480.
- O'Connell OJ, Rodriguez-Vial M, Ost DE, Jimenez CA, Grosu HB. Bronchoscopic Management of a Benign Obstructing Pedunculated Tumor. Ann Am Thorac Soc 12(11):1715-7, 2015. PMID: 26540423.
- Grosu HB, Ost DE, Morice RC, Eapen GA, Li L, Song J, Lei X, Lazarus DR, Casal RF, Jimenez CA. Mediastinal Granulomatous Inflammation and Overall Survival in Patients with a History of Malignancy. Ann Am Thorac Soc 12(10):1534-41, 2015. e-Pub 2015. PMID: 26284901.
- Wiener RS, Gould MK, Arenberg DA, Au DH, Fennig K, Lamb CR, Mazzone PJ, Midthun DE, Napoli M, Ost DE, Powell CA, Rivera MP, Slatore CG, Tanner NT, Vachani A, Wisnivesky JP, Yoon SH, ATS/ACCP Committee on Low-Dose CT Lung Cancer Screening in Clinical Practice. An Official American Thoracic Society/American College of Chest Physicians Policy Statement: Implementation of Low-dose Computed Tomography Lung Cancer Screening Programs in Clinical Practice. Am J Respir Crit Care Med 192(7):881-91, 2015. PMID: 26426785.
- Grosu HB, Iliesiu M, Caraway NP, Medeiros LJ, Lei X, Jimenez CA, Morice RC, Casal RF, Ost D, Eapen GA. Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for the Diagnosis and Subtyping of Lymphoma. Ann Am Thorac Soc 12(9):1336-1344, 2015. PMID: 26146788.
- Ost DE, Sterman DH. Interventional Bronchoscopy in 2015. Removing Endoluminal and Methodological Obstructions. Ann Am Thorac Soc 12(9):1265-6, 2015. PMID: 26372802.
- Grosu HB, Morice RC, Sarkiss M, Bashoura L, Eapen GA, Jimenez CA, Faiz S, Lazarus DR, Casal RF, Ost DE. Safety of Flexible Bronchoscopy, Rigid Bronchoscopy, and Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in Patients with Malignant Space-occupying Brain Lesions. Chest 147(6):1621-1628, 2015. e-Pub 2014. PMID: 25393333.
- Ost DE, Ernst A, Grosu HB, Lei X, Diaz-Mendoza J, Slade M, Gildea TR, Machuzak MS, Jimenez CA, Toth J, Kovitz KL, Ray C, Greenhill S, Casal RF, Almeida FA, Wahidi MM, Eapen GA, Feller-Kopman D, Morice RC, Benzaquen S, Tremblay A, Simoff M, AQuIRE Bronchoscopy Registry. Therapeutic Bronchoscopy for Malignant Central Airway Obstruction: Success Rates and Impact on Dyspnea and Quality of Life. Chest 147(5):1282-1298, 2015. e-Pub 2014. PMID: 25358019.
- Casal RF, Lazarus DR, Kuhl K, Nogueras-González G, Perusich S, Green LK, Ost DE, Sarkiss M, Jimenez CA, Eapen GA, Morice RC, Cornwell L, Austria S, Sharafkanneh A, Rumbaut RE, Grosu H, Kheradmand F. Randomized Trial of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Under General Anesthesia versus Moderate Sedation. Am J Respir Crit Care Med 191(7):796-803, 2015. PMID: 25574801.
- Ong P, Grosu H, Eapen GA, Rodriguez M, Lazarus D, Ost D, Jimenez CA, Morice R, Bandi V, Tamara L, Cornwell L, Green L, Zhu A, Casal RF. Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Systematic Nodal Staging of Lung Cancer in Patients with N0 Disease by Computed Tomography and Integrated Positron Emission Tomography-computed Tomography. Ann Am Thorac Soc 12(3):415-9, 2015. PMID: 25584815.
- Ost DE, Ernst A, Grosu HB, Lei X, Diaz-Mendoza J, Slade M, Gildea TR, Machuzak M, Jimenez CA, Toth J, Kovitz KL, Ray C, Greenhill S, Casal RF, Almeida FA, Wahidi M, Eapen GA, Yarmus LB, Morice RC, Benzaquen S, Tremblay A, Simoff M. Complications Following Therapeutic Bronchoscopy for Malignant Central Airway Obstruction: Results of the AQuIRE Registry. Chest 148:450-471, 2015. e-Pub 2015. PMID: 25741903.
- Grosu HB, Bashoura L, Ost D, Ordonez NG, Faiz SA. Critical Airway Obstruction Due to Pseudomembranous Aspergillus Tracheitis. Am J Respir Crit Care Med 190(11):e65-6, 2014. PMID: 25436790.
- Godoy MC, Saldana DA, Rao PP, Vlahos I, Naidich DP, Benveniste MF, Erasmus JJ, Marom EM, Ost D. Multidetector CT Evaluation of Airway Stents: What the Radiologist Should Know. Radiographics 34(7):1793-806, 2014. PMID: 25384279.
- Ost DE, Jimenez CA, Lei X, Cantor SB, Grosu HB, Lazarus DR, Faiz SA, Bashoura L, Shannon VR, Balachandran D, Noor L, Hashmi YB, Casal RF, Morice RC, Eapen GA. Quality-adjusted Survival Following Treatment of Malignant Pleural Effusions with Indwelling Pleural Catheters. Chest 145(6):1347-1356, 2014. e-Pub 2014. PMID: 24480929.
- Ost D, Niu J, Elting L, Buchholz TA, Giordano SH. Determinants of Practice Patterns and Quality Gaps in Lung Cancer Staging and Diagnosis. Chest 145:1097-1113, 2014. e-Pub 2013.
- Almeida FA, Casal RF, Jimenez CA, Eapen GA, Uzbeck M, Sarkiss M, Rice D, Morice RC, Ost DE. Quality Gaps and Comparative Effectiveness in Lung Cancer Staging: The Impact of Test Sequencing on Outcomes. Chest 144(6):1776-1782, 2013. e-Pub 2013. PMID: 23703671.
- Garcia JB, Lei X, Wierda W, Cortes JE, Dickey BF, Evans SE, Ost DE. Pneumonia During Remission Induction Chemotherapy in Patients with Acute Leukemia. Ann Am Thorac Soc 10(5):432-440, 2013. PMID: 23987587.
- Casal RF, Iribarren J, Eapen G, Ost D, Morice R, Lan C, Cornwell L, Almeida FA, Grosu H, Jimenez CA. Safety and Effectiveness of Microdebrider Bronchoscopy for the Management of Central Airway Obstruction. Respirology 18(6):1011-5, 2013. e-Pub 2013. PMID: 23520982.
- Grosu HB, Casal RF, Morice RC, Nogueras-González GM, Eapen GA, Ost D, Sarkiss MG, Jimenez CA. Bronchoscopic Findings and Bleeding Control Predict Survival in Patients with Solid Malignancies Presenting with Mild Hemoptysis. Ann Am Thorac Soc 4(4):342-349, 2013. PMID: 23952853.
- Grosu HB, Morice RC, Ost D, Eapen GA, Jimenez CA. A Watery Mediastinal Mass. Am J Respir Crit Care Med 187(10):1135-1136, 2013. PMID: 23675716.
- Eapen GA, Shah AM, Lei X, Jimenez CA, Morice RC, Yarmus L, Filner J, Ray C, Michaud G, Greenhill SR, Sarkiss M, Casal R, Rice D, Ost DE, American College of Chest Physicians Quality Improvement Registry, Education, and Evaluation (AQuIRE) Participants. Complications, Consequences, and Practice Patterns of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: Results of the AQuIRE Registry. Chest 143(4):1044-1053, 2013. e-Pub 2012. PMID: 23117878.
- Grosu HB, Jimenez CA, Morice RC, Ost D, Sarkiss MG, Eapen GA. Cryptogenic Bronchial Stenosis. Am J Respir Crit Care Med 187(3):327, 2013. PMID: 23378438.
- Casal RF, Bashoura L, Ost D, Chiu HT, Faiz SA, Jimenez CA, Morice RC, Eapen GA. Detecting Medical Device Complications: Lessons from an Indwelling Pleural Catheter Clinic. Am J Med Qual 28(1):69-75, 2013. e-Pub 2012. PMID: 22763365.
- Yarmus LB, Akulian J, Lechtzin N, Yasin F, Ernst A, Ost DE, Ray C, Greenhill SR, Jimenez CA, Filner J, Feller-Kopman D. Comparison of 21-gauge and 22-gauge Aspiration Needle in Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: Results of the AQuIRE Registry. Chest 143:1036-1043, 2013. e-Pub 2012.
- Grosu HB, Eapen GA, Morice RC, Jimenez CA, Casal RF, Almeida FA, Sarkiss MG, Ost DE. Stents are Associated with Increased Risk of Respiratory Infections in Patients Undergoing Airway Interventions for Malignant Airway Disease. Chest 144:441-449, 2013. e-Pub 2013.
- Ost DE, Yeung J, Tanoue LT, Gould M. Clinical and Organizational Factors in the Initial Evaluation of Patients with Lung Cancer: Diagnosis and Management of Lung Cancer. Chest 143:e121S-141S, 2013.
- Casal RF, Staerkel GA, Ost D, Almeida FA, Uzbeck MH, Eapen GA, Jimenez CA, Nogueras-Gonzalez GM, Sarkiss M, Morice RC. Randomized Clinical Trial of Endobronchial Ultrasound Needle Biopsy with and without Aspiration. Chest 142(3):568-573, doi:10.1378/chest.11-0692, 2012. e-Pub 2011. PMID: 22156610.
- Grosu HB, Jimenez CA, Eapen GA, Ost D, Moran C, Morice RC. The Iron Lady. Am J Respir Crit Care Med 186(5):460, 2012. PMID: 22942346.
- Nair A, Godoy MC, Holden EL, Madden BP, Chua F, Ost DE, Roos JE, Naidich DP, Vlahos I. Multidetector CT and Postprocessing in Planning and Assisting in Minimally Invasive Bronchoscopic Airway Interventions. Radiographics 32(5):E201-32, 2012. PMID: 22977038.
- Ost DE, Shah AM, Lei X, Godoy MC, Jimenez CA, Eapen GA, Jani P, Larson AJ, Sarkiss MG, Morice RC. Respiratory Infections Increase the Risk of Granulation Tissue Formation Following Airway Stenting in Patients With Malignant Airway Obstruction. Chest 141(6):1473-81, 2012. e-Pub 2011. PMID: 22194585.
- Grosu HB, Morice RC, Almeida FA, Ost D, Eapen GA, Jimenez CA. A Flexible Knot to Untie. Am J Respir Crit Care Med 185(11):1244, 2012. PMID: 22661525.
- Shah A, Ost D, Eapen GA, Morice RC, Jimenez CA. Diagnostic Methylene Blue Test for Stent Covered Tracheoesophageal Fistula. Am J Respir Crit Care Med 185(7):e9, 2012. PMID: 22467810.
- Ost DE, Gould MK. Decision Making in the Patient with Pulmonary Nodules. Am J Respir Crit Care Med 185(4):363-72, 2012. e-Pub 2011. PMID: 21980032.
- Shah AM, Morice RC, Ost D, Eapen GA, Betancourt SL, Jimenez CA. High-riding Pericardial Recess Mimicking Metastatic Mediastinal Lymph Node. Am J Respir Crit Care Med 185(1):e1, 2012. PMID: 22210796.
- Ost DE, Ernst A, Lei X, Feller-Kopman D, Eapen GA, Kovitz KL, Herth FJ, Simoff M, AQuIRE Bronchoscopy Registry. Diagnostic Yield of Endobronchial Ultrasound Guided Transbronchial Needle Aspiration: Results of the AQuIRE Registry. Chest 140(6):1557-1566, 2011. e-Pub 2011. PMID: 21659432.
- Peñuelas O, Frutos-Vivar F, Fernández C, Anzueto A, Epstein SK, Apezteguía C, González M, Nin N, Raymondos K, Tomicic V, Desmery P, Arabi Y, Pelosi P, Kuiper M, Jibaja M, Matamis D, Ferguson ND, Esteban A, Ventila Group. As part of the Ventila Group, site PI.. Characteristics and Outcomes of Ventilated Patients According to Time to Liberation from Mechanical Ventilation. Am J Respir Crit Care Med 184(4):430-7, 2011. PMID: 21616997.
- Lombardi R, Nin N, Lorente JA, Frutos-Vivar F, Ferguson ND, Hurtado J, Apezteguia C, Desmery P, Raymondos K, Tomicic V, Cakar N, González M, Elizalde J, Nightingale P, Abroug F, Jibaja M, Arabi Y, Moreno R, Matamis D, Anzueto A, Esteban A, VENTILA Group. As part of the Ventila Group, site PI.. An Assessment of the Acute Kidney Injury Network Creatinine-based Criteria in Patients Submitted to Mechanical Ventilation. Clin J Am Soc Nephrol 6(7):1547-55, 2011. e-Pub 2011. PMID: 21700822.
- Pelosi P, Ferguson ND, Frutos-Vivar F, Anzueto A, Putensen C, Raymondos K, Apezteguia C, Desmery P, Hurtado J, Abroug F, Elizalde J, Tomicic V, Cakar N, Gonzalez M, Arabi Y, Moreno R, Esteban A, Ventila Study Group. As part of the Ventila Group, site PI.. Management and Outcome of Mechanically Ventilated Neurologic Patients. Crit Care Med 39(6):1482-92, 2011. PMID: 21378554.
- Kett DH, Azoulay E, Echeverria PM, Vincent JL, Extended Prevalence of Infection in ICU Study (EPIC II) Group of Investigators. As part of the EPIC II investigators, site PI.. Candida Bloodstream Infections in Intensive Care Units: Analysis of the Extended Prevalence of Infection in Intensive Care Unit Study. Crit Care Med 39(4):665-70, 2011. PMID: 21169817.
- Filner JJ, Bonura EJ, Lau ST, Abounasr KK, Naidich D, Morice RC, Eapen GA, Jimenez CA, Casal RF, Ost D. Bronchoscopic Fibered Confocal Fluorescence Microscopy Image Characteristics and Pathologic Correlations. J Bronchology Interv Pulmonol 18(1):23-30, 2011. PMID: 23169014.
- Casal RF, Jimenez CA, Mehran RJ, Eapen GA, Ost D, Sarkiss M, Morice RC. Infected Mediastinal Bronchogenic Cyst Successfully Treated by Endobronchial Ultrasound-guided Fine-needle Aspiration. Ann Thorac Surg 90(4):e52-3, 2010. PMID: 20868780.
- Morice RC, Jimenez CA, Eapen GA, Mehran RJ, Keus L, Ost D. Using Quantitative Breath Sound Measurements to Predict Lung Function Following Resection. J Cardiothorac Surg 5(1):81. e-Pub 2010. PMID: 20939900.
- Ost DE, Poch D, Fadel A, Wettimuny S, Ginocchio C, Wang XP. Mini-bronchoalveolar Lavage Quantitative Polymerase Chain Reaction for Diagnosis of Methicillin-resistant Staphylococcus aureus Pneumonia. Crit Care Med 38(7):1536-41, 2010. e-Pub 2010. PMID: 20473148.
- Ernst A, Simoff M, Ost D, Michaud G, Chandra D, Herth FJ. A Multi-center, Prospective, Advanced Diagnostic Bronchoscopy Outcomes Registry. Chest 138(1):165-70, 2010. e-Pub 2010. PMID: 20363846.
- Sterman DH, Mehta AC, Wood DE, Mathur PN, McKenna RJ, Ost DE, Truwit JD, Diaz P, Wahidi MM, Cerfolio R, Maxfield R, Musani AI, Gildea T, Sheski F, Machuzak M, Haas AR, Gonzalez HX, Springmeyer SC, IBV Valve US Pilot Trial Research Team. A Multicenter Pilot Study of a Bronchial Valve for the Treatment of Severe Emphysema. Respiration 79(3):222-33, 2010. e-Pub 2009. PMID: 19923790.
- Ost D, Eapen GA, Jimenez CA, Morice RC. Improving Procedural Training and Certification in Pulmonary Medicine. Chest 137(1):6-8, 2010. PMID: 20051398.
- Ozcakar B, Martinez CH, Morice RC, Eapen GA, Ost D, Sarkiss MG, Chiu HT, Jimenez CA. Does Pleural Fluid Appearance Really Matter? The Relationship Between Fluid Appearance and Cytology, Cell Counts, and Chemical Laboratory Measurements in Pleural Effusions of Patients with Cancer. J Cardiothorac Surg 5:63, 2010. PMID: 20718978.
- Springmeyer SC, Bolliger CT, Waddell TK, Gonzalez X, Wood DE, IBV Valve Pilot Trials Research Teams. As part of the IBV Pilot trials team, site PI for trial.. Treatment of Heterogeneous Emphysema Using the Spiration IBV Valves. Thorac Surg Clin 19(2):247-53, ix-x, 2009. PMID: 19662968.
- Godoy MC, Ost D, Geiger B, Novak C, Nonaka D, Vlahos I, Naidich DP. Utility of Virtual Bronchoscopy-guided Transbronchial Biopsy for the Diagnosis of Pulmonary Sarcoidosis: Report of Two Cases. Chest 134(3):630-6, 2008. e-Pub 2008. PMID: 18490401.
- Ernst A, Simoff M, Ost D, Goldman Y, Herth FJF. Prospective Risk-adjusted Morbidity and Mortality Outcome Analysis After Therapeutic Bronchoscopic Procedures: Results of a Multi-institutional Outcomes Database. Chest 134(3):514-9, 2008. e-Pub 2008. PMID: 18641088.
- Ost D, Shah R, Anasco E, Lusardi L, Doyle J, Austin C, Fein A. A Randomized Trial of CT Fluoroscopic-guided Bronchoscopy vs Conventional Bronchoscopy in Patients with Suspected Lung Cancer. Chest 134(3):507-13, 2008. e-Pub 2008. PMID: 18641093.
- Ost D, Goldberg J, Rolnitzky L, Rom WN. Survival After Surgery in Stage IA and IB Non-small Cell Lung Cancer. Am J Respir Crit Care Med 177(5):516-23, 2008. e-Pub 2007. PMID: 18006887.
- Esteban A, Ferguson ND, Meade MO, Frutos-Vivar F, Apezteguia C, Brochard L, Raymondos K, Nin N, Hurtado J, Tomicic V, González M, Elizalde J, Nightingale P, Abroug F, Pelosi P, Arabi Y, Moreno R, Jibaja M, D'Empaire G, Sandi F, Matamis D, Montañez AM, Anzueto A, VENTILA Group. As part of the Ventila Group, site PI.. Evolution of Mechanical Ventilation in Response to Clinical Research. Am J Respir Crit Care Med 177(2):170-177, 2008. e-Pub 2007. PMID: 17962636.
- Corwin HL, Gettinger A, Fabian TC, May A, Pearl RG, Heard S, An R, Bowers PJ, Burton P, Klausner MA, Corwin MJ, EPO Critical Care Trials Group. As part of EPI Trials Group, site PI.. Efficacy and Safety of Epoetin Alfa in Critically Ill Patients. N Engl J Med 357(10):965-76, 2007. PMID: 17804841.
- Wood DE, McKenna RJ, Yusen RD, Sterman DH, Ost DE, Springmeyer SC, Gonzalez HX, Mulligan MS, Gildea T, Houck WV, Machuzak M, Mehta AC. A Multicenter Trial of an Intrabronchial Valve for Treatment of Severe Emphysema. J Thorac Cardiovasc Surg 133(1):65-73, 2007. e-Pub 2006. PMID: 17198782.
- Ost D, Tepper J, Mihara H, Lander O, Heinzer R, Fein A. Duration of Anticoagulation Following Venous Thromboembolism: A Meta-analysis. JAMA 294:706-15, 2005. PMID: 16091573.
- Ost D, Khanna D, Shah R, Hall CS, Shah S, Lesser M, Fein AM. Theory versus Practice: Impact of Spiral Computed Tomography on the Diagnosis of Pulmonary Embolism in a Community Hospital Setting. Respiration 71:450-7, 2004. PMID: 15467321.
- Bernard GR, Margolis BD, Shanies HM, Ely EW, Wheeler AP, Levy H, Wong K, Wright T, for the Extended Evaluation of Recombinant Human Activated Protein C United States Investigators. As part of the ENHANCE study group, site PI.. Extended Evaluation of Recombinant Human Activated Protein C United States Trial (ENHANCE US): A Single-arm, Phase 3B, Multicenter Study of Drotrecogin Alfa (Activated) in Severe Sepsis. Chest 125:2206-2216, 2004.
- Mojavarian A, Ost D. Tracheobronchial Glomus Tumor. J Bronchology 11:188-193, 2004.
- Spragg R, Lewis J, Walmrath H, et al for the Venticute Study Group. As part of the Venticute Study Group, site PI.. Effect of Recombinant Surfactant Protein C-based Surfactant on the Acute-respiratory Distress Syndrome. N Engl J Med 351:884-92, 2004.
- Ost DE, Hall CS, Joseph G, Ginocchio C, Condon S, Kao E, LaRusso M, Itzla R, Fein AM. Decision Analysis of Antibiotic and Diagnostic Strategies in Ventilator-associated Pneumonia. Am J Respir Crit Care Med 168:1060-7, 2003. PMID: 12842855.
- The MATISSE Investigators. Subcutaneous Fondaparinux versus Intravenous Unfractionated Heparin in the Initial Treatment of Pulmonary Embolism. N Engl J Med 349:1695-1702, 2003.
- Ernst A, Freitag L, Feller-Kopman D, LoCicero J, Ost D. Photodynamic Therapy for Endobronchial Obstruction is Safely Performed with Flexible Bronchoscopy. J Bronchol Intervent Pulmonol 10:260-263, 2003.
- Friedman D, Shulman L, Ost D, Fein A.. Dual Stenting of Bronchoesophageal Fistula. J Bronchol 10:272-275, 2003.
- Ost D, DeRosiers A, Britt E J, Fein A, Lesser M, Mehta A.. Assessment of a Bronchoscopy Simulator. Am J Respir Crit Care Med 164:1-8, 2001.
- Ost D, Rozenshtein A, Saffran L, Snider A. The Negative Predictive Value of Spiral Computed Tomography for the Diagnosis of Pulmonary Embolism in Patients with Nondiagnostic Ventilation-perfusion Scans. Am J Med 110(1):16-21, 2001. PMID: 11152860.
- Saffron LS, Ost D, Fein AM, Schiff MJ.. Outpatient Pleurodesis of Malignant Pleural Effusions, Using a Small Bore Pigtail Catheter. Chest 118:417-22, 2000.
- Shah S, Ost D.. Photodynamic Therapy: A Case Series Demonstrating its Role in Mechanically Ventilated Patients. Chest 118:1419-1423, 2000.
- Ost D, Joseph C, Sogoloff H, Menezes G.. Primary Pulmonary Melanoma: Case Report and Literature Review. Mayo Clinic Proc 74:62-66, 1999.
- Ost D, Yeldandi A, Cugell D.. Acute Sarcoid Myositis: Case Report and Review of the Literature. Chest 107:879-82, 1995.
- Sachs MK, Huang CM, Ost D, Jungkind DL.. Failure of Dithiothreitol and Pronase to Reveal a False-positive Cryptococcal Antigen Determination in Cerebrospinal Fluid. Am J Clin Pathol 96:381-4, 1991.
- Owen CS, Sykes NL, Shuler RL, Ost D. Non-calcium Environmental Sensitivity of Intracellular Indo-1. Analytical Biochemistry 192:142-8, 1991.
Invited Articles
- Chang CH, Ost DE. Malignant pleural disease: a pragmatic guide to diagnosis. Curr Opin Pulm Med 28(4):282-287, 2022. PMID: 35749791.
- Schwalk AJ, Ost DE. Indwelling Pleural Catheters. Clin Chest Med 42(4):739-750, 2021. PMID: 34774179.
- Lin J, Ost DE. Robotic bronchoscopy for peripheral pulmonary lesions: a convergence of technologies. Curr Opin Pulm Med 27(4):229-239. e-Pub 2021. PMID: 33973554.
- Marcoux M, Ost DE. What's new in endobronchial ultrasound for mediastinal staging?. Curr Opin Pulm Med 26(4):346-358, 2020. PMID: 32487873.
- Nasim F, Ost DE.. Management of the Solitary Pulmonary Nodule. Curr Opin Pulm Med 25(4):344-53, 2019. e-Pub 2019.
- Miller RJ, Casal RF, Lazarus DR, Ost DE, Eapen GA. Flexible Bronchoscopy. Clin Chest Med 39:1-16, 2018.
- Sabath BF, Ost DE. Update on Airway Stents. Curr Opin Pulm Med 24:343-349, 2018. e-Pub 2018. PMID: 29538079.
- Debiane LG, Ost DE. Advances in the Management of Malignant Pleural Effusion. Curr Opin Pulm Med 23(4):317-322, 2017. PMID: 28426471.
- Kinsey CM, Ost DE. Randomization in Diagnostic and Therapeutic Interventional Pulmonary Trials. J Bronchology Interv Pulmonol 23(4):272-278, 2016. PMID: 27764005.
- Mudambi L, Ost DE. Advanced Bronchoscopic Techniques for the Diagnosis of Peripheral Pulmonary Lesions. Curr Opin Pulm Med 22(4):309-318, 2016. PMID: 27055076.
- Evans SE, Ost DE. Pneumonia in the Neutropenic Cancer Patient. Curr Opin Pulm Med 21(3):260-71, 2015. PMID: 25784246.
- Saettele TM, Ost DE. Multimodality Systematic Approach to Mediastinal Lymph Node Staging in Non-small Cell Lung Cancer. Respirology 19:800-808, 2014.
- Casal RF, Ost DE, Eapen GA. Flexible Bronchoscopy. Clin Chest Med 34(3):341-352, 2013. e-Pub 2013. PMID: 23993807.
- Lazarus DR, Ost DE. How and When to Use Genetic Markers for Nonsmall Cell Lung Cancer. Curr Opin Pulm Med 19(4):331-339, 2013. PMID: 23715289.
- Casal RF, Ost DE, Eapen G.. Flexible Bronchoscopy. Clin Chest Med 34:341-352, 2013.
- Lazarus DR, Ost DE. The Solitary Pulmonary Nodule – Deciding When to Act?. Semin Respir Crit Care Med 34:748-761, 2013.
- Grosu HB, Eapen GA, Jimenez CA, Morice RC, Ost D. Lung Cancer Screening: Making the Transition from Research to Clinical Practice. Curr Opin Pulm Med 18(4):295-303, 2012. PMID: 22617813.
- Almeida FA, Uzbeck M, Ost D. Initial Evaluation of the Nonsmall Cell Lung Cancer Patient: Diagnosis and Staging. Curr Opin Pulm Med 16(4):307-14, 2010. PMID: 20453649.
- Amdo T, Godoy MC, Ost D, Naidich DP. Imaging-bronchoscopic Correlations for Interventional Pulmonology. Thorac Surg Clin 20(1):103-19, 2010. PMID: 20378063.
- Amdo T, Godoy MC, Ost D, Naidich DP. Imaging-bronchoscopic Correlations for Interventional Pulmonology. Radiol Clin North Am 47(2):271-87, 2009. PMID: 19249456.
- Poch DS, Ost DE. What are the Important Risk Factors for Healthcare-associated Pneumonia?. Semin Respir Crit Care Med 30(1):26-35, 2009. e-Pub 2009. PMID: 19199184.
- Sarkiss M, Casal R, Ost D, Morice R, Eapen G, Jimenez C.. Anesthesia for Interventional Bronchoscopy. Minverva Pneumol(231-42), 2009.
- Filner JJ, Ost D. Principles of Staging as Applied to Nonsmall Cell Lung Cancer. Curr Opin Pulm Med 14(4):287-91, 2008. PMID: 18520260.
- Kollef MH, Morrow LE, Baughman RP, Craven DE, McGowan JE, Micek ST, Niederman MS, Ost D, Paterson DL, Segreti J. Health Care-associated Pneumonia (HCAP): A Critical Appraisal to Improve Identification, Management, and Outcomes--Proceedings of the HCAP Summit. Clin Infect Dis 46:S296-334, 2008. PMID: 18429676.
- Gould MK, Fletcher J, Iannettoni MD, Lynch WR, Midthun DE, Naidich DP, Ost DE. Evaluation of Patients with Pulmonary Nodules: When is it Lung Cancer?: ACCP Evidence-based Clinical Practice Guidelines (2nd Edition). Chest 132(3 Suppl):108S-130S, 2007. PMID: 17873164.
- Shulman L, Ost D. Advances in Bronchoscopic Diagnosis of Lung Cancer. Curr Opin Pulm Med 13(4):271-7, 2007. PMID: 17534172.
- Edelson J, Shah R, Ost D. A 45 Year Old Man with Left Lung Hypoperfusion and Possible Pulmonary Embolism. Chest 128(2):1032-6, 2005. PMID: 16100204.
- Shulman L, Ost D. Managing Infection in the Critical Care Unit: How Can Infection Control Make the ICU Safe?. Crit Care Clin 21(1):111-28, 2005. PMID: 15579356.
- Ost D, Fein A. Management Strategies for the Solitary Pulmonary Nodule. Curr Opin Pulm Med 10:272-8, 2004.
- Ost D, Fein A. The Role of Invasive Diagnostic Techniques in Pneumonia. Sem Resp Infect 18:65-67, 2003.
- Hall CS, Ost D. Effectiveness of Programs to Decrease Antimicrobial Resistance in the Intensive Care Unit. Sem Resp Infect 18:112-121, 2003.
- Ost D.. The Structure of a Computer-assisted Treatment Plan for Inpatients - Meeting Standards and Improving Care. (Invited Commentary). J Information Tech in Healthcare 1:183-185, 2003.
- Ost D. Photodynamic Therapy in Lung Cancer. Methods Mol Med 75:507-26, 2003.
- Ost D, Fein AM, Feinsilver SH.. The Solitary Pulmonary Nodule. New England Journal of Medicine 348:2535-42, 2003.
- Khanna D, Ost D. Life Threatening Infections in the Upper Airway, Part 1. J. Crit Illness 17:10-21, 2002.
- Khanna D, Ost D. Life Threatening Infections in the Upper Airway, Part 2. J Crit Illness 17:134-140, 2002.
- Mehrishi S, Ost D.. Photodynamic Therapy: How I Do It. Journal of Bronchology 9:218-222, 2002.
- Ost D, Fein A. Evaluation and Management of the Solitary Pulmonary Nodule. Am J Respir Crit Care Med 162(3 Pt 1):782-787, 2000. PMID: 10988081.
- Ost D.. Photodynamic Therapy in Lung Cancer. Oncology 14:379-392, 2000.
- Ost D, Fein AM. Evaluation and Management of the Solitary Pulmonary Nodule. Am J Respir Crit Care Med 162:782-787, 2000.
- Ost D, Joseph C, Sogoloff H, Menezes G.. Pulmonary Melanoma. Resp Dis 6:14-18, 2000.
- Saffron L, Ost D. Management of Malignant Pleural Effusions. Emergency Medicine:pp 63-71, 1999.
- Ost D. Solitary Pulmonary Nodules. Emergency Medicine:pp 90-97, 1998.
- Ost D. Life Threatening Deep Neck Space Infections. Clin Pulm Med 4:316-23, 1997. e-Pub 1997.
- Ost D, Corbridge T.. Independent Lung Ventilation. Clinics in Chest Medicine 17:591-602, 1996.
Editorials
- Ost DE. Criteria for Effective Definitions of Centrally Located Tumors: Practical, Predictive, and Reproducible. Chest 161(5):1140-1142, 2022. PMID: 35526886.
- Ost DE. Machine Learning for Treating Complicated Parapneumonic Effusions: The Fundamentals Still Apply. Chest 154(3):471-473, 2018. PMID: 30195338.
- Ost DE. The Future of Interventional Pulmonology and the Role of the Journal. J Bronchology Interv Pulmonol 25(3):161-164, 2018. PMID: 29944586.
- Ost DE. Quantifying Outcomes for Palliative Pleural Interventions. Lancet Respir Med 6:648-649, 2018. PMID: 30037715.
- Ost DE. The Importance of Negative Studies: Autofluorescence Bronchoscopy for Lung Cancer Screening. Chest 150(5):993-994, 2016. PMID: 27832892.
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CV information above last modified January 26, 2024