Edwin J. Ostrin, M.D., Ph.D.

Peer-Reviewed Articles

1. Gendarme S, Irajizad E, Long JP, Fahrmann JF, Dennison JB, Ghasemi SM, Dou R, Volk RJ, Meza R, Toumazis I, Canoui-Poitrine F, Hanash SM, Ostrin EJ. Impact of Comorbidities on the Mortality Benefits of Lung Cancer Screening: A Post-Hoc Analysis of the PLCO and NLST Trials. J Thorac Oncol, 2025. e-Pub 2025. PMID: 39798695.
2. Irajizad E, Fahrmann JF, Toumazis I, Vykoukal J, Dennison JB, Shen Y, Do KA, Ostrin EJ, Feng Z, Hanash S. Biomarker trajectory for earlier detection of lung cancer. EBioMedicine 108:105377, 2024. e-Pub 2024. PMID: 39353277.
3. Moghaddam SJ, Savai R, Salehi-Rad R, Sengupta S, Kammer MN, Massion P, Beane JE, Ostrin EJ, Priolo C, Tennis MA, Stabile LP, Bauer AK, Sears CR, Szabo E, Rivera MP, Powell CA, Kadara H, Jenkins BJ, Dubinett SM, Houghton AM, Kim CF, Keith RL. Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non-Small Cell Lung Cancer. An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med 210(5):548-571, 2024. e-Pub 2024. PMID: 39115548.
4. Hemmati, M, Ishizawa, S, Meza, R, Ostrin, EJ, Hanash, S, Antonoff, MB, Schaefer, AJ, Tammemagi, M, Toumazis, I. Benchmarking lung cancer screening programmes with adaptive screening frequency against the optimal screening schedules derived from the ENGAGE framework. EClinicalMedicine 74, 2024. e-Pub 2024.
5. Hemmati M, Ishizawa S, Meza R, Ostrin E, Hanash SM, Antonoff M, Schaefer AJ, Tammemagi MC, Toumazis I. Benchmarking lung cancer screening programmes with adaptive screening frequency against the optimal screening schedules derived from the ENGAGE framework: a comparative microsimulation study. EClinicalMedicine 74:102743, 2024. e-Pub 2024. PMID: 39764179.
6. Pan K, Owens J, Elamin Y, Lu C, Routbort M, Zhang J, Fossella F, Negrao MV, Altan M, Pozadzides J, Skoulidis F, Tsao A, Cascone T, Heymach JV, Ostrin E, Le X. Mutational Characteristics and Clinical Outcomes for Lung Adenocarcinoma With EGFR Germline Mutations. J Thorac Oncol 19(10):1438-1448, 2024. e-Pub 2024. PMID: 38866326.
7. Song L, Irajizad E, Rundle A, Sesso HD, Gaziano JM, Vykoukal JV, Do KA, Dennison JB, Ostrin EJ, Fahrmann JF, Perera F, Hanash S. Validation of a Blood-Based Protein Biomarker Panel for a Risk Assessment of Lethal Lung Cancer in the Physicians' Health Study. Cancers (Basel) 16(11), 2024. e-Pub 2024. PMID: 38893188.
8. Hu X, Zhu B, Vokes N, Fujimoto J, Rojas Alvarez FR, Heeke S, Moreira AL, Solis LM, Haymaker C, Velcheti V, Sterman DH, Pass HI, Cheng C, Lee JJ, Zhang J, Wei Z, Wu J, Le X, Ostrin E, Toumazis I, Gibbons D, Su D, Fukuoka J, Antonoff MB, Gerber DE, Li C, Kadara H, Wang L, Davis M, Heymach JV, Hannash S, Wistuba I, Dubinett S, Alexandrov L, Lippman S, Spira A, Futreal AP, Reuben A, Zhang J. The evolution of lung adenocarcinoma precursors is associated with chromosomal instability and transition from innate to adaptive immune response/evasion. Res Sq, 2024. e-Pub 2024. PMID: 38798564.
9. Salehjahromi M, Karpinets TV, Sujit SJ, Qayati M, Chen P, Aminu M, Saad MB, Bandyopadhyay R, Hong L, Sheshadri A, Lin J, Antonoff MB, Sepesi B, Ostrin EJ, Toumazis I, Huang P, Cheng C, Cascone T, Vokes NI, Behrens C, Siewerdsen JH, Hazle JD, Chang JY, Zhang J, Lu Y, Godoy MCB, Chung C, Jaffray D, Wistuba I, Lee JJ, Vaporciyan AA, Gibbons DL, Gladish G, Heymach JV, Wu CC, Zhang J, Wu J. Synthetic PET from CT improves diagnosis and prognosis for lung cancer: Proof of concept. Cell Rep Med 5(3):101463, 2024. e-Pub 2024. PMID: 38471502.
10. Nofal S, Niu J, Resong P, Jin J, Merriman KW, Le X, Katki H, Heymach J, Antonoff MB, Ostrin E, Wu J, Zhang J, Toumazis I. Personal history of cancer as a risk factor for second primary lung cancer: Implications for lung cancer screening. Cancer Med 13(5):e7069, 2024. e-Pub 2024. PMID: 38466021.
11. Tai MC, Bantis LE, Parhy G, Kato T, Tanaka I, Chow CW, Fujimoto J, Behrens C, Hase T, Kawaguchi K, Fahrmann JF, Ostrin EJ, Yokoi K, Chen-Yoshikawa TF, Hasegawa Y, Hanash SM, Wistuba II, Taguchi A. Circulating microRNA Panel for Prediction of Recurrence and Survival in Early-Stage Lung Adenocarcinoma. Int J Mol Sci 25(4), 2024. e-Pub 2024. PMID: 38397007.
12. Irajizad, E, Fahrmann, JF, Marsh, T, Vykoukal, JV, Dennison, JB, Long, JP, Do, K, Feng, Z, Hanash, S, Ostrin, EJ. Mortality Benefit of a Blood-Based Biomarker Panel for Lung Cancer on the Basis of the Prostate, Lung, Colorectal, and Ovarian Cohort. Journal of Clinical Oncology 41(27):4360-4368, 2023. e-Pub 2023. PMID: 37379494.
13. León-Letelier, RA, Abdel Sater, AH, Chen, Y, Park, S, Wu, R, Irajizad, E, Dennison, JB, Katayama, H, Vykoukal, JV, Hanash, S, Ostrin, EJ, Fahrmann, JF. Kynureninase Upregulation Is a Prominent Feature of NFR2-Activated Cancers and Is Associated with Tumor Immunosuppression and Poor Prognosis. Cancers 15(3), 2023. e-Pub 2023. PMID: 36765792.
14. Ostrin, EJ, Rider, NL, Alousi, AM, Irajizad, E, Li, L, Peng, Q, Kim, ST, Bashoura, L, Arain, MH, Noor, L, Patel, NJ, Mehta, RS, Popat, UR, Hosing, C, Jenq, RR, Rondon, G, Hanash, S, Paczesny, S, Shpall, E, Champlin, RE, Dickey, BF, Sheshadri, A. A Nasal Inflammatory Cytokine Signature Is Associated with Early Graft-versus-Host Disease of the Lung after Allogeneic Hematopoietic Cell Transplantation. ImmunoHorizons 7(6):421-430, 2023. e-Pub 2023. PMID: 37289498.
15. Vykoukal, JV, Fahrmann, JF, Patel, NJ, Shimizu, M, Ostrin, EJ, Dennison, JB, Ivan, C, Goodman, G, Thornquist, MD, Barnett, MJ, Feng, Z, Calin, GA, Hanash, S. Contributions of Circulating microRNAs for Early Detection of Lung Cancer. Cancers 14(17), 2022. e-Pub 2022. PMID: 36077759.
16. Irajizad, E, Fahrmann, JF, Long, JP, Vykoukal, JV, Kobayashi, M, Capello, M, Yu, CY, Cai, Y, Hsiao, FC, Patel, NJ, Park, S, Peng, Q, Dennison, JB, Kato, T, Tai, MC, Taguchi, A, Kadara, HN, Wistuba, II, Katayama, H, Do, K, Hanash, S, Ostrin, EJ. A Comprehensive Search of Non-Canonical Proteins in Non-Small Cell Lung Cancer and Their Impact on the Immune Response. International journal of molecular sciences 23(16), 2022. e-Pub 2022. PMID: 36012199.
17. Yuan, B, Clowers, MJ, Velasco, WV, Peng, SA, Peng, Q, Shi, Y, Ramos-Castañeda, M, Zarghooni, M, Yang, SY, Babcock, R, Chang, SH, Heymach, JV, Zhang, J, Ostrin, EJ, Watowich, SS, Kadara, HN, Moghaddam, SM. Targeting IL-1β as an immunopreventive and therapeutic modality for K-ras–mutant lung cancer. JCI Insight 7(11), 2022. e-Pub 2022. PMID: 35471938.
18. Fahrmann, JF, Tanaka, I, Irajizad, E, Mao, X, Dennison, JB, Murage, EN, Casabar, JP, Mayo, J, Peng, Q, Çeliktaş, M, Vykoukal, JV, Park, S, Taguchi, A, Delgado, O, Tripathi, SC, Katayama, H, Solis Soto, LM, Rodriguez Canales, J, Behrens, MC, Wistuba, II, Hanash, S, Ostrin, EJ. Mutational Activation of the NRF2 Pathway Upregulates Kynureninase Resulting in Tumor Immunosuppression and Poor Outcome in Lung Adenocarcinoma. Cancers 14(10), 2022. e-Pub 2022. PMID: 35626147.
19. Fahrmann, JF, Marsh, T, Irajizad, E, Patel, NJ, Murage, EN, Vykoukal, JV, Dennison, JB, Do, K, Ostrin, EJ, Spitz, MR, Lam, S, Shete, S, Meza, R, Tammemagi, M, Feng, Z, Hanash, S. Blood-Based Biomarker Panel for Personalized Lung Cancer Risk Assessment. Journal of Clinical Oncology 40(8):876-883, 2022. e-Pub 2022. PMID: 34995129.
20. Tanaka, I, Dayde, D, Tai, MC, Mori, H, Solis Soto, LM, Tripathi, SC, Fahrmann, JF, Unver, N, Parhy, G, Jain, R, Parra Cuentas, ER, Murakami, Y, Aguilar-Bonavides, C, Mino, B, Çeliktaş, M, Dhillon, DS, Casabar, JP, Nakatochi, M, Stingo, F, Baladandayuthapani, V, Wang, H, Katayama, H, Dennison, JB, Lorenzi, PL, Do, K, Fujimoto, J, Behrens, MC, Ostrin, EJ, Rodriguez Canales, J, Hase, T, Fukui, T, Kajino, T, Kato, S, Yatabe, Y, Hosoda, W, Kawaguchi, K, Yokoi, K, Chen, F, Hasegawa, Y, Gazdar, AF, Wistuba, II, Hanash, S, Taguchi, A. SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1-Negative Lung Adenocarcinomas. Journal of the National Cancer Institute 114(2):290-301, 2022. e-Pub 2022. PMID: 34524427.
21. Sinjab, A, Han, G, Treekitkarnmongkol, W, Hara, K, Brennan, P, Dang, M, Hao, D, Wang, R, Dai, E, Dejima, H, Zhang, J, Bogatenkova, E, Sanchez Espiridion, B, Chang, K, Little, DR, Bazzi, S, Tran, LM, Krysan, K, Behrens, MC, Duose, D, Parra Cuentas, ER, Raso, G, Solis Soto, LM, Fukuoka, J, Zhang, J, Sepesi, B, Cascone, T, Byers, LA, Gibbons, DL, Chen, J, Moghaddam, SM, Ostrin, EJ, Rosen, DG, Heymach, JV, Scheet, PA, Dubinett, SM, Fujimoto, J, Wistuba, II, Stevenson, CS, Spira, A, Wang, L, Kadara, HN. Resolving the spatial and cellular architecture of lung adenocarcinoma by multiregion single-cell sequencing. Cancer discovery 11(10):2506-2523, 2021. e-Pub 2021. PMID: 33972311.
22. Fahrmann, JF, Katayama, H, Irajizad, E, Chakraborty, A, Kato, T, Mao, X, Park, S, Murage, EN, Rusling, LA, Yu, CY, Cai, Y, Hsiao, FC, Dennison, JB, Tran, HT, Ostrin, EJ, Wilson, DO, Yuan, JM, Vykoukal, JV, Hanash, S. Plasma based protein signatures associated with small cell lung cancer. Cancers 13(16), 2021. e-Pub 2021. PMID: 34439128.
23. Han, G, Sinjab, A, Hara, K, Treekitkarnmongkol, W, Brennan, P, Chang, K, Bogatenkova, E, Sanchez Espiridion, B, Behrens, MC, Solis Soto, LM, Gao, B, Girard, L, Zhang, J, Sepesi, B, Cascone, T, Byers, LA, Gibbons, DL, Chen, J, Moghaddam, SM, Ostrin, EJ, Scheet, PA, Fujimoto, J, Shay, JW, Heymach, JV, Minna, JD, Dubinett, SM, Wistuba, II, Stevenson, CS, Spira, A, Wang, L, Kadara, HN. Single-cell expression landscape of SARS-CoV-2 receptor ACE2 and host proteases in normal and malignant lung tissues from pulmonary adenocarcinoma patients. Cancers 13(6):1-13, 2021. e-Pub 2021. PMID: 33809063.
24. Ostrin, EJ, Bantis, LE, Wilson, DO, Patel, NJ, Wang, R, Kundnani, DL, Adams-Haduch, J, Dennison, JB, Fahrmann, JF, Chiu, HT, Gazdar, AF, Feng, Z, Yuan, JM, Hanash, S. Contribution of a Blood-Based Protein Biomarker Panel to the Classification of Indeterminate Pulmonary Nodules. Journal of Thoracic Oncology 16(2):228-236, 2021. e-Pub 2021. PMID: 33137463.
25. Treekitkarnmongkol, W, Hassane, M, Sinjab, A, Chang, K, Hara, K, Rahal, Z, Zhang, J, Lu, W, Sivakumar, S, McDowell, TL, Kantrowitz, J, Zhou, J, Lang, W, Xu, L, Ochieng, J, Nunomura-Nakamura, S, Deng, S, Behrens, MC, Raso, G, Fukuoka, J, Reuben, A, Ostrin, EJ, Parra Cuentas, ER, Solis Soto, LM, Spira, A, McAllister, F, Cascone, T, Wistuba, II, Moghaddam, SM, Scheet, PA, Fujimoto, J, Kadara, HN. Augmented Lipocalin-2 Is Associated with Chronic Obstructive Pulmonary Disease and Counteracts Lung Adenocarcinoma Development. American journal of respiratory and critical care medicine 203(1):90-101, 2021. e-Pub 2021. PMID: 32730093.
26. Deng, S, Ramos-Castañeda, M, Velasco, WV, Clowers, MJ, Gutierrez, BA, Noble, O, Dong, Y, Zarghooni, M, Alvarado, L, Caetano, MS, Yang, SY, Ostrin, EJ, Behrens, MC, Wistuba, II, Stabile, LP, Kadara, HN, Watowich, SS, Moghaddam, SM. Interplay between estrogen and Stat3/NF-κB-driven immunomodulation in lung cancer. Carcinogenesis 41(11):1529-1542, 2020. e-Pub 2020. PMID: 32603404.
27. Fahrmann, JF, Mao, X, Irajizad, E, Katayama, H, Capello, M, Tanaka, I, Kato, T, Wistuba, II, Maitra, A, Ostrin, EJ, Hanash, S, Vykoukal, JV. Plasma-derived extracellular vesicles convey protein signatures that reflect pathophysiology in lung and pancreatic adenocarcinomas. Cancers 12(5), 2020. e-Pub 2020. PMID: 32370304.
28. Vila Ellis, L, Cain, MP, Hutchison, V, Flodby, P, Crandall, ED, Borok, Z, Zhou, B, Ostrin, EJ, Wythe, JD, Chen, J. Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Developmental cell 52(5):617-630.e6, 2020. e-Pub 2020. PMID: 32059772.
29. Hu, X, Fujimoto, J, Ying, L, Fukuoka, J, Ashizawa, K, Sun, W, Reuben, A, Chow, CW, Mcgranahan, N, Chen, R, Hu, J, Godoy, M, Tabata, K, Kuroda, K, Shi, L, Li, J, Behrens, MC, Parra Cuentas, ER, Little, L, Gumbs, C, Mao, X, Song, X, Tippen, S, Thornton, R, Kadara, HN, Scheet, PA, Roarty, EB, Ostrin, EJ, Wang, X, Carter, B, Antonoff, MB, Zhang, J, Vaporciyan, AA, Pass, HI, Swisher, SG, Heymach, JV, Lee, JJ, Wistuba, II, Hong, WK, Futreal, A, Su, D, Zhang, J. Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma. Nature communications 10(1), 2019. e-Pub 2019. PMID: 31278276.
30. Park, YH, Snook, JD, Ostrin, EJ, Kim, SB, Chen, R, Frankfort, BJ. Transcriptomic profiles of retinal ganglion cells are defined by the magnitude of intraocular pressure elevation in adult mice. Scientific reports 9(1), 2019. e-Pub 2019. PMID: 30796289.
31. Williams, R, Bakshi, S, Ostrin, EJ, Ostrin, LA. Continuous Objective Assessment of Near Work. Scientific reports 9(1), 2019. e-Pub 2019. PMID: 31061427.
32. Little, DR, Gerner-Mauro, KN, Flodby, P, Crandall, ED, Borok, Z, Akiyama, H, Kimura, S, Ostrin, EJ, Chen, J. Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1. Proceedings of the National Academy of Sciences of the United States of America 116(41):20545-20555, 2019. e-Pub 2019. PMID: 31548395.
33. De La Garza, MM, Cumpian, AM, Daliri, S, Castro-Pando, S, Umer, M, Gong, L, Khosravi, N, Caetano, MS, Ramos-Castañeda, M, Flores, AG, Beltran, EC, Tran, HT, Tuvim, MJ, Ostrin, EJ, Dickey, BF, Evans, CM, Moghaddam, SM. COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation. Oncotarget 9(68):32972-32983, 2018. e-Pub 2018. PMID: 30250643.
34. Khosravi, N, Caetano, MS, Cumpian, AM, Unver, N, De la Garza Ramos, C, Noble, O, Daliri, S, Hernandez, B, Gutierrez, BA, Evans, S, Hanash, S, Alekseev, A, Yang, Y, Chang, SH, Nurieva, R, Kadara, HN, Chen, J, Ostrin, EJ, Moghaddam, SM. IL22 promotes kras-mutant lung cancer by induction of a protumor immune response and protection of stemness properties. Cancer Immunology Research 6(7):788-797, 2018. e-Pub 2018. PMID: 29764837.
35. Unver, N, Delgado, O, Zeleke, K, Cumpian, AM, Tang, X, Caetano, MS, Wang, H, Katayama, H, Yu, H, Szabo, E, Wistuba, II, Moghaddam, SM, Hanash, S, Ostrin, EJ. Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol. International journal of cancer 142(7):1405-1417, 2018. e-Pub 2018. PMID: 29134640.
36. Ostrin, EJ, Little, DR, Gerner-Mauro, KN, Sumner, EA, Rı́os-Corzo, R, Ambrosio, E, Holt, SE, Forcioli-Conti, N, Akiyama, H, Hanash, S, Kimura, S, Huang, SX, Chen, J. β-catenin maintains lung epithelial progenitors after lung specification. Development (Cambridge) 145(5), 2018. e-Pub 2018. PMID: 29440304.
37. Tripathi, SC, Fahrmann, JF, Çeliktaş, M, Aguilar, M, Marini, KD, Jolly, MK, Katayama, H, Wang, H, Murage, EN, Dennison, JB, Watkins, DN, Levine, H, Ostrin, EJ, Taguchi, A, Hanash, S. MCAM mediates chemoresistance in small-cell lung cancer via the PI3K/AKT/ SOX2 signaling pathway. Cancer Research 77(16):4414-4425, 2017. e-Pub 2017. PMID: 28646020.
38. Çeliktaş, M, Tanaka, I, Tripathi, SC, Fahrmann, JF, Aguilar-Bonavides, C, Villalobos, P, Delgado, O, Dhillon, DS, Dennison, JB, Ostrin, EJ, Wang, H, Behrens, MC, Do, K, Gazdar, A, Hanash, S, Taguchi, A. Role of CPS1 in cell growth, metabolism, and prognosis in LKB1-inactivated lung adenocarcinoma. Journal of the National Cancer Institute 109(3), 2017. e-Pub 2017. PMID: 28376202.
39. Vykoukal, JV, Sun, N, Aguilar-Bonavides, C, Katayama, H, Tanaka, I, Fahrmann, JF, Capello, M, Fujimoto, J, Aguilar, M, Wistuba, II, Taguchi, A, Ostrin, EJ, Hanash, S. Plasma-derived extracellular vesicle proteins as a source of biomarkers for lung adenocarcinoma. Oncotarget 8(56):95466-95480, 2017. e-Pub 2017. PMID: 29221141.
40. Caetano, MS, Zhang, H, Cumpian, AM, Gong, L, Unver, N, Ostrin, EJ, Daliri, S, Chang, SH, Ochoa, CE, Hanash, S, Behrens, MC, Wistuba, II, Sternberg, C, Kadara, HN, Ferreira, CG, Watowich, SS, Moghaddam, SM. IL6 blockade reprograms the lung tumor microenvironment to limit the development and progression of K-ras-mutant lung cancer. Cancer Research 76(11):3189-3199, 2016. e-Pub 2016. PMID: 27197187.
41. Tripathi, SC, Peters, HC, Taguchi, A, Katayama, H, Wang, H, Momin, AA, Jolly, MK, Çeliktaş, M, Rodriguez Canales, J, Liu, H, Behrens, MC, Wistuba, II, Ben-Jacob, E, Levine, H, Molldrem, JJ, Hanash, S, Ostrin, EJ. Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome. Proceedings of the National Academy of Sciences of the United States of America 113(11):E1555-E1564, 2016. e-Pub 2016. PMID: 26929325.
42. Yang, JX, Hernandez, B, Alanis, DM, del Pilar, ON, Vila Ellis, L, Akiyama, H, Evans, S, Ostrin, EJ, Chen, J. The development and plasticity of alveolar type 1 cells. Development (Cambridge) 143(1):54-65, 2016. e-Pub 2016. PMID: 26586225.
43. Solberg, OD, Ostrin, EJ, Love, MI, Peng, JC, Bhakta, NR, Hou, L, Nguyen, C, Solon, M, Nguyen, C, Barczak, AJ, Zlock, LT, Blagev, DP, Finkbeiner, WE, Ansel, KM, Arron, J, Erle, DJ, Woodruff, PG. Airway epithelial miRNA expression is altered in asthma. American journal of respiratory and critical care medicine 186(10):965-974, 2012. e-Pub 2012. PMID: 22955319.
44. Ostrin, EJ, Li, Y, Hoffman, KL, Liu, J, Wang, K, Zhang, L, Mardon, G, Chen, R. Genome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless. Genome research 16(4):466-476, 2006. e-Pub 2006. PMID: 16533912.
45. Pappu, KS, Ostrin, EJ, Middlebrooks, BW, Sili, BT, Chen, R, Atkins, MR, Gibbs, RA, Mardon, G. Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund. Development 132(12):2895-2905, 2005. e-Pub 2005. PMID: 15930118.
46. Tavsanli, BC, Ostrin, EJ, Burgess, HK, Middlebrooks, BW, Pham, TA, Mardon, G. Structure-function analysis of the Drosophila retinal determination protein Dachshund. Developmental Biology 272(1):231-247, 2004. e-Pub 2004. PMID: 15242803.
47. Rayapureddi, JP, Kattamuri, C, Steinmetz, BD, Frankfort, BJ, Ostrin, EJ, Mardon, G, Hegde, RS. Eyes absent represents a class of protein tyrosine phosphatases. Nature 426(6964):295-298, 2003. e-Pub 2003. PMID: 14628052.
48. Lloyd, TE, Versteken, P, Ostrin, EJ, Phillippi, A, Lichtarge, O, Bellen, HJ. A genome-wide search for synaptic vesicle cycle proteins in Drosophila. Neuron 26(1):45-50, 2000. e-Pub 2000. PMID: 10798391.
49. Geissler, HJ, Davis, K, Laine, GA, Ostrin, EJ, Mehlhorn, U, Hekmat, K, David Warters, R, Allen, SJ. Myocardial protection with high-dose β-blockade in acute myocardial ischemia. European Journal of Cardio-thoracic Surgery 17(1):63-70, 2000. e-Pub 2000. PMID: 10735414.

Other Articles

1. Deboever N, Ostrin EJ, Antonoff MB Liquid Biopsy as an Adjunct to Lung Screening Imaging. Thorac Surg Clin 33(4):411-419, 2023. PMID: 37806743.
2. León-Letelier, RA, Dou, R, Vykoukal, JV, Sater, AH, Ostrin, EJ, Hanash, S, Fahrmann, JF The kynurenine pathway presents multi-faceted metabolic vulnerabilities in cancer. Frontiers in Oncology 13, 2023. PMID: 37876966.
3. Tripathi SC, Vedpathak D, Ostrin EJ The Functional and Mechanistic Roles of Immunoproteasome Subunits in Cancer. Cells 10(12), 2021. PMID: 34944095.
4. Hu, X, Fujimoto, J, Ying, L, Fukuoka, J, Ashizawa, K, Sun, W, Reuben, A, Chow, CW, Mcgranahan, N, Chen, R, Hu, J, Godoy, M, Tabata, K, Kuroda, K, Shi, L, Li, J, Behrens, MC, Parra Cuentas, ER, Little, L, Gumbs, C, Mao, X, Song, X, Tippen, S, Thornton, R, Kadara, HN, Scheet, PA, Roarty, EB, Ostrin, EJ, Wang, X, Carter, B, Antonoff, MB, Zhang, J, Vaporciyan, AA, Pass, HI, Swisher, SG, Heymach, JV, Lee, JJ, Wistuba, II, Hong, WK, Futreal, A, Su, D, Zhang, J Author Correction. Nature communications 12(1), 2021. PMID: 33980839.
5. Ostrin, EJ, Sidransky, D, Spira, A, Hanash, S Biomarkers for lung cancer screening and detection. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 29(12):2411-2415, 2020. PMID: 33093160.
6. Fahrmann, JF, Vykoukal, JV, Ostrin, EJ Amino Acid Oncometabolism and Immunomodulation of the Tumor Microenvironment in Lung Cancer. Frontiers in Oncology 10, 2020. PMID: 32266129.
7. Hanash, S, Ostrin, EJ, Fahrmann, JF Blood based biomarkers beyond genomics for lung cancer screening. Translational Lung Cancer Research 7(3):327-335, 2018. PMID: 30050770.
8. Tsou, P, Katayama, H, Ostrin, EJ, Hanash, S The emerging role of b cells in tumor immunity. Cancer Research 76(19):5591-5601, 2016. PMID: 27634765.
9. Hanash, S, Taguchi, A, Wang, H, Ostrin, EJ Deciphering the complexity of the cancer proteome for diagnostic applications. Expert Review of Molecular Diagnostics 16(4):399-405, 2016. PMID: 26694525.
10. Zeidner, JF, Ostrin, EJ, Sydnor, E, Fine, D, Sperati, CJ The Tissue's the Issue. American Journal of Medicine 123(5):420-422, 2010. PMID: 20399317.