Effrosyni Apostolidou, M.D., Ph.D.
Department of Pulmonary Medicine, Division of Internal Medicine
Present Title & Affiliation
Primary Appointment
Associate Professor, Section of Benign Hematology, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
2004 | National and Kapodistrian University of Athens, Medical School, Athens, GRC, PHD, Medicine |
1993 | National and Kapodistrian University of Athens, Medical School, Athens, GRC, MD, Medicine |
Postgraduate Training
2012-2016 | Clinical Fellowship, Hematology/Oncology Fellowship, University of Texas M.D. Anderson Cancer Center, Houston, TX |
2009-2012 | Clinical Residency, Internal Medicine Residency, University of Pennsylvania Health Care System, Pennsylvania Hospital, Philadelphia, PA |
1998-2002 | Clinical Fellowship, Hematology Fellowship, National and Kapodistrian University of Athens, Laikon General Hospital, Athens |
1995-1997 | Clinical Residency, Internal Medicine Residency, KAT” General Hospital, Athens |
1993-1994 | M.D. Social Services, M.D. Social Services, Anthili Fthioditos Health Care Center, Athens |
Board Certifications
2017 | American Board of Internal Medicine |
2014 | American Board of Internal Medicine |
2003 | Central Board of Health, Greece |
Experience & Service
Institutional Committee Activities
BCM Hematology-Oncology Fellowship Steering Committee, Baylor College of Medicine/Michael E. Debakey VA Medical Center, 2022 - 2023
Member, Cancer Committee, Baylor College of Medicine/Michael E. Debakey VA Medical Center, 2021 - 2023
Honors & Awards
2019 | Dean’s Teaching Excellence Award, University of Texas Health Science Center at Houston, |
2013 | The Shannon Timmons Fellowship Award on Leukemia Research, University of Texas MD Anderson Cancer Center |
2000 | First Award for Best Conference Presentation, 11th Conference of the Hellenic Society of Hematology |
Selected Publications
Peer-Reviewed Articles
- Khan S, Alam ST, Ramos RT, Mbue JE, Apostolidou E, Rivero GA, Yellapragada SV. Luspatercept in Low-Risk Myelodysplastic Syndrome: A Real-World Single Institution Case Series. Clin Hematol Int 4(4):148-151, 2022. e-Pub 2022. PMID: 35997953.
- Goswamy R, Ajufo H, Maiti A, Brown R, Juneja H, Apostolidou E. Refractory Hydroa Vacciniforme-like Lymphoma: Biological Insights from Morphoproteomic Analysis. Int J Hematol Oncol Stem Cell Res 16(3):177-183, 2022. PMID: 36694700.
- Apostolidou E, Lachowiez C, Juneja HS, Qiao W, Ononogbu O, Miller-Chism CN, Udden M, Ma H, Mims MP. Clinical Outcomes of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia in a County Hospital System. Clin Lymphoma Myeloma Leuk 21(11):e895-e902, 2021. e-Pub 2021. PMID: 34376374.
- Hu Z, Singhi EK, Apostolidou E, Mai B, Juneja HS, Hu S. Mass-forming neoplastic extramedullary hematopoiesis mimics myeloid sarcoma in a patient with chronic phase chronic myeloid leukemia. Int J Lab Hematol 43(3):e135-e137, 2021. e-Pub 2020. PMID: 33314782.
- Apostolidou E, Kantarjian H, Thomas D, Burger I, Borthakur G, Verstovsek S. Phase II study of sunitinib in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis. Clin Lymphoma Myeloma Leuk 10(4):281-4, 2010. PMID: 20709665.
- Yin CC, Abruzzo LV, Qiu X, Apostolidou E, Cortes JE, Medeiros LJ, Lu G. del(15q) is a recurrent minor-route cytogenetic abnormality in the clonal evolution of chronic myelogenous leukemia. Cancer Genet Cytogenet 192(1):18-23, 2009. PMID: 19480932.
- Apostolidou E, Kantarjian HM, Verstovsek S. JAK2 inhibitors: A reality? A hope?. Clin Lymphoma Myeloma 9 Suppl 3:S340-5, 2009. PMID: 19778862.
- Alvarado Y, Apostolidou E, Swords R, Giles FJ. Emerging therapeutic options for Philadelphia-positive acute lymphocytic leukemia. Expert Opin Emerg Drugs 12(1):165-79, 2007. PMID: 17355221.
- Apostolidou E, Swords R, Alvarado Y, Giles FJ. Treatment of acute lymphoblastic leukaemia : a new era. Drugs 67(15):2153-71, 2007. PMID: 17927282.
- Swords R, Apostolidou E, Giles F. Troxacitabine in leukemia. Hematology 11(5):321-9, 2006. PMID: 17607581.
- Yee KW, Zeng Z, Konopleva M, Verstovsek S, Ravandi F, Ferrajoli A, Thomas D, Wierda W, Apostolidou E, Albitar M, O'Brien S, Andreeff M, Giles FJ. Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies. Clin Cancer Res 12(17):5165-73, 2006. PMID: 16951235.
- Terpos E, Samarkos M, Meletis C, Apostolidou E, Tsironi M, Korovesis K, Mavrogianni D, Viniou N, Meletis J. Unusual association between increased bone resorption and presence of paroxysmal nocturnal hemoglobinuria phenotype in multiple myeloma. Int J Hematol 78(4):344-8, 2003. PMID: 14686493.
- Apostolidou E, Cortes J, Tsimberidou A, Estey E, Kantarjian H, Giles FJ. Pilot study of gemtuzumab ozogamicin, liposomal daunorubicin, cytarabine and cyclosporine regimen in patients with refractory acute myelogenous leukemia. Leuk Res 27(10):887-91, 2003. PMID: 12860007.
- Apostolidou E, Estey E, Cortes J, Garcia-Manero G, Faderl S, Thomas D, Tsimberidou A, Kantarjian H, Giles FJ. Mitoxantrone and prolonged infusion gemcitabine as salvage therapy in patients with acute myelogenous leukemia. Leuk Res 27(4):301-4, 2003. PMID: 12531220.
- Meletis J, Terpos E, Mavrogianni D, Lilakos K, Apostolidou E, Tsironi M, Korovessis K, Komninaka V, Sarantopoulos A, Samarkos M, Konstantopoulos K.. Aplastic anaemia with large ‘PNH – like’ red cell population. Haema 6(1):103-106, 2003.
- Meletis J, Terpos E, Tsironi M, Komninaka V, Apostolidou E, Samarkos M.. Flashes in clinical haematology- case 21 :Type –I Gaucher’s disease with monoclonal gammopathy of unknown significance. Haema 6(1):107-108, 2003.
- Meletis J, Terpos E, Tsironi M, Komninaka V, Apostolidou E, Samarkos M.. Flashes in clinical haematology – case 22: Type II mixed cryoglobulinemia, HCV-associated peripheral neuropathy. Haema 6(2):256-57, 2003.
- Meletis J, Terpos E, Tsironi M, Komninaka V, Apostolidou E, Samarkos M, Vaiopoulos G.. Flashes in clinical haematology – case 23: Cutaneous T-cell lymphoma; Sezary syndrome. Haema 6(3):409-10, 2003.
- Meletis J, Terpos E, Komninaka V, Tsironi M, Apostolidou E, Samarkos M, Vaiopoulos G.. Flashes in clinical haematology – case 25: Chronic lymphocytic leukemia, autoimmune haemolytic anaemia, Kaposi’s sarcoma. Haema 6(4):544-45, 2003.
- Alvarado Y, Kantarjian HM, Cortes JE, Apostolidou E, Bivins C, Giles FJ. Troxacitabine activity in extramedullary myeloid leukemia. Hematology 7(3):179-85, 2002. PMID: 12243982.
- Viniou N, Terpos E, Galanopoulos A, Kritikou-Griva E, Akel S, Michalis E, Apostolidou E, Georgiadou D, Kouraklis A, Parharidou A, Kokkini G, Symeonidis A, Anagnostopoulos NI, Christakis JI, Tasiopoulou A, Loukopoulos D, Yataganas X. Treatment of anemia in low-risk myelodysplastic syndromes with amifostine. In vitro testing of response. Ann Hematol 81(4):182-6, 2002. e-Pub 2002. PMID: 11976818.
- Meletis J, Terpos E, Samarkos M, Meletis C, Apostolidou E, Komninaka V, Anargyrou K, Korovesis K, Mavrogianni D, Variami E, Viniou N, Konstantopoulos K. Red cells with paroxysmal nocturnal hemoglobinuria-phenotype in patients with acute leukemia. Hematology 7(2):69-74, 2002. PMID: 12186694.
- Meletis J, Terpos E, Samarkos M, Meletis C, Apostolidou E, Komninaka V, Korovesis K, Anargyrou K, Benopoulou O, Mavrogianni D, Variami E, Viniou N, Konstantopoulos K. Detection of CD55- and/or CD59-deficient red cell populations in patients with plasma cell dyscrasias. Int J Hematol 75(1):40-4, 2002. PMID: 11843289.
- Terpos E, Pamphilis C, Tsironi M, Apostolidou E, Komninaka V, Samarkos M, Chatzinikolaou P, Korovesis K, Kostantopoulos K, Yataganas X, Meletis J.. Hemophagocytic syndrome associated with adrenocortical carcinoma: a case report and review of the literature. Haema 5(2):136-37, 2002.
- Meletis J, Terpos E, Apostolidou E, Samarkos M.. Flashes in clinical haematology- case 18 : Inherited orotic aciduria type I. Haema 5(2):136-37, 2002.
- Meletis J, Terpos E, Apostolidou E, Anargyrou K, Samarkos M.. Flashes in clinical hematology- case 19 : Plasmacytic leukemia, pseudomonas aeruginosa sepsis. Haema 5(3):249-50, 2002.
- Meletis J, Terpos E, Apostolidou E, Tsironi M, Samarkos M.. Acute monoblastic leukaemia – leukemia cutis after progression of refractory anemia with ringed sideroblasts and multilineage dysplasia. Archives of Hellenic Medicine; 19(6):710-12, 2002.
- Meletis J, Anargyrou K, Terpos E, Apostolidou E, Tsironi M, Samarkos M.. Flashes in clinical haematology-case 20: Secondary acute non-lymphoblastic leukemia. Haema 5(4):347, 2002.
- Korkolopoulou P, Apostolidou E, Pavlopoulos PM, Kavantzas N, Vyniou N, Thymara I, Terpos E, Patsouris E, Yataganas X, Davaris P. Prognostic evaluation of the microvascular network in myelodysplastic syndromes. Leukemia 15(9):1369-76, 2001. PMID: 11516097.
- Meletis J, Terpos E, Samarkos M, Meletis C, Konstantopoulos K, Komninaka V, Apostolidou E, Benopoulou O, Korovesis K, Mavrogianni D, Variami E, Yataganas X, Loukopoulos D. Detection of CD55 and/or CD59 deficient red cell populations in patients with aplastic anaemia, myelodysplastic syndromes and myeloproliferative disorders. Haematologia (Budap) 31(1):7-16, 2001. PMID: 11345408.
- Meletis J, Terpos E, Samarkos M, Meletis C, Apostolidou E, Komninaka V, Korovesis K, Mavrogianni D, Boutsis D, Variami E, Viniou N, Konstantopoulos K, Loukopoulos D. Detection of CD55- and/or CD59-deficient red cell populations in patients with lymphoproliferative syndromes. Hematol J 2(1):33-7, 2001. PMID: 11920231.
- Meletis J, Dalekou M, Samarkos M, Paravasiliou E, Meletis C, Konstantopoulos K, Apostolidou E, Komninaka V, Terpos E, Benopoulou O, Korovesis K, Variami E, Loukopoulos D. Fetal Erythropoiesis after Allogeneic Bone Marrow Transplantation Estimated by the Peripheral Blood Erythrocytes Containing Hemoglobin F (F-cells). Hematology 5(6):447-53, 2001. PMID: 27419348.
- Meletis J, Terpos E, Apostolidou E, Samarkos M.. Hereditary stomatocytosis with megaloblastic anemia 18(4):416, 2001.
- Meletis J, Terpos E, Apostolidou E, Samarkos M.. Lead poisoning’. Archives of Hellenic Medicine; 18(5):538, 2001.
- Meletis J, Apostolidou E, Terpos E, Samarkos M.. Flashes in clinical hematology- case 13: Anaplastic myeloma. Haema 4(1):52-53, 2001.
- Meletis J, Terpos E, Komninaka V, Apostolidou E.. Essential mixed cryoglobulinemia (type II: with monoclonal and polyclonal component). Archives of Hellenic Medicine; 17(6):641, 2000.
- Meletis J, Apostolidou E, Komninaka V, Samarkos M.. Flashes in clinical haematology - case 10: CLL-prolymphocytic leukemia - VZV infection 3(2):119-20, 2000.
- Meletis J, Apostolidou E, Komninaka V, Samarkos M.. Flashes in clinical haematology - case 11: Malaria. Megaloblastic anaemia (folic acid deficiency) 3(3):193-94, 2000.
- Meletis J, Apostolidou E, Komninaka V, Samarkos M.. Anaplastic Myeloma’. Archives of Hellenic Medicine 17(1):109-12, 2000.
- Terpos E, Samarkos M, Meletis C, Komninaka V, Apostolidou E, Benopoulou O, Korovesis K, Mavrogianni D, Anargyrou K, Viniou N, Variami E, Konstantopoulos K, Meletis J. Detection of CD55 and/or CD59 deficient red cell populations in patients with aplastic anemia and myelodysplastic syndromes. Archives of Hellenic Medicine; 17(4):383-89, 2000.
- Meletis J, Apostolidou E, Komninaka V, Samarkos M.. Flashes in clinical haematology - case 9: AML type M3 variant, mild disseminated intravascular coagulation 3(1):60-61, 2000.
- Meletis J, Terpos E, Apostolidou E and Samarkos M.. Flashes in clinical haematology - case 12: Haemoglobin E disease with erythroblastopenia 3(4):242-43, 2000.
- Terpos E, Samarkos M, Meletis C, Apostolidou E, Komninaka V, Meletis JC.. Detection of CD55 and /or CD59 deficient red cell populations in patients with myeloproliferative syndromes 77(5):471-75, 2000.
- Meletis J, Apostolidou E, Konstantopoulos K.. Flashes in clinical haematology - case 6: SLE- fasculitis-cold haemaglutinin disease (CHAD). Haema;(2):109, 1999.
Abstracts
- Khan S, Taveras S, Ramos R, Mbue J, Apostolidou E, Rivero G, Yellapragada S.. Luspatercept in Low-risk MDS: A real world single institution case series’. Fourth Annual Hematologic Malignancies Symposium, Baylor College of Medicine, 2022.
- Bhakta P, Lachowiez C, Huang Q, Apostolidou E.. Clinical Outcomes of Patients with Newly Diagnosed Acute Myeloid Leukemia treated in a County Hospital System’ Fourth Annual Hematologic Malignancies Symposium, Baylor College of Medicine, 2022.
- Apostolidou E, Khatri P, Thomas E, Savitz SI, Zha A.. Utility and Costs of Inpatient Thrombophilia Testing in Ischemic Stroke Patients Aged 18-60’. International StrokeConference 2020, Los Angeles, CA, February 19-21, 2020. Stroke 51(Issue Suppl_1,), 2020.
- Apostolidou E, Lachowiez C, Qiao W, Lee S, Ma H, Short N, Idowu M, Mims M, Juneja H.. Clinical Outcomes of Patients with Acute Lymphoblastic Leukemia in a County Hospital System’. Society of Hematologic Oncology Annual Meeting, Clinical Lymphoma, Myeloma and Leukemia 20(Suppl_1):108-109, 2020.
- Apostolidou E, Hatami M, Savitz SI, Thomas E, Khatri P, Zha A.. Assessment and Reduction of Unnecessary Thrombophilia Testing in Patients 18-60 Years with Acute Cryptogenic Ischemic Stroke. The 61st ASH Annual Meeting and Exposition Exposition, Orlando, FL, December 6-9, 2019. Blood: 134(Suppl.1):3397, 2019.
- Tsekos G, Boukouvalas V, Fragiathakis C, Apostolidou E, Roulia E.. ‘Acute renal failure due to ciprofloxacin administration’. The Twenty-second Annual Hellenic Medical Congress,. Hellenic Medical Congress Proceedings Abstract book::99, 1996.
- Tsekos G, Theodosis I, Roulia E, Apostolidou E, Fragiathakis C.. Postular psoriatic arthritis, imitating Reiter’s syndrome. Postular psoriatic arthritis, imitating Reiter’s syndrome, 1996.
- Tsekos G, Fragiathakis C, Yotsidou A, Kostelidou T, Roulia E, Apostolidou E.. ‘Therapy of malaria caused by plasmodium vivax with quinolones’. Hellenic Medical Congress Proceedings:104, 1996.
Patient Reviews
CV information above last modified July 28, 2023