Evangelia Koutelou, PhD
Department of Epigenetics and Molecular Carcinogenesis, Division of Discovery Science
Present Title & Affiliation
Primary Appointment
Assistant Professor, Department of Epigenetics and Molecular Carcinogenesis, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Houston, TX
Education & Training
Degree-Granting Education
| 2006 | University of Crete - Stowers Institute for Medical Research, Iraklio - Kansas City, MO, USA, PHD, Molecular Biology and Biomedicine |
| 2001 | University of Crete, Iraklio, GRC, MS, Molecular Biology and Biomedicine |
| 1999 | University of Crete, Iraklio, GRC, BS, Biology |
Postgraduate Training
| 2013-2013 | Cold Spring Harbor Course, Mouse Development, Stem Cells and Cancer, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY |
| 2008-2013 | Research Fellowship, Epigenetics, MD Anderson Cancer Center, Houston, TX |
| 2007-2008 | Research Fellowship, Stowers Institute for Medical Research, Kansas City, MO |
Experience & Service
Academic Appointments
Instructor, Department of Epigenetics and Molecular Carcinogenesis, Division of Basic Science Research, The University of Texas MD Anderson Cancer Center, Smithville, Texas, TX, 2013 - 2021
Honors & Awards
| 2002 | Extra-mural Predoctoral Fellowship, Propondis |
Selected Publications
Peer-Reviewed Articles
- Wang L, Koutelou E, Hirsch C, McCarthy R, Schibler A, Lin K, Lu Y, Jeter C, Shen J, Barton MC, Dent SYR. GCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation. Stem Cell Reports 10(1):287-299, 2018. e-Pub 2017. PMID: 29249668.
- Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, Lin K, McIvor E, Li W, Zhang Y, Florens L, Byrum SD, Mackintosh SG, Calhoun-Davis T, Koutelou E, Wang L, Tang DG, Tackett AJ, Washburn MP, Workman JL, Dent SY. ATXN7L3 and ENY2 coordinate activity of multiple H2B deubiquitinases important for cellular proliferation and tumor growth. Mol Cell 62(4):558-71, 2016. e-Pub 2016. PMID: 27132940.
- Schibler A, Koutelou E, Tomida J, Wilson-Pham M, Wang L, Lu Y, Cabrera AP, Chosed RJ, Li W, Li B, Shi X, Wood RD, Dent SY. Histone H3K4 methylation regulates deactivation of the Spindle Assembly Checkpoint through direct binding of Mad2. Genes Dev 30(10):1187-97, 2016. e-Pub 2016. PMID: 27198228.
- Lan X, Koutelou E, Schibler AC, Chen YC, Grant PA, Dent SY. The pathogenic ATXN7-92Q indirectly impairs SAGA deubiquitinating activity. Mol Cell Biol 35(10):1777-87, 2015. e-Pub 2015. PMID: 25755283.
- Butler JS, Koutelou E, Schibler AC, Dent SY. Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease. Epigenomics 4(2):163-77, 2012. PMID: 22449188.
- Wilson MA, Koutelou E, Hirsch C, Akdemir K, Schibler A, Barton MC, Dent SY. Ubp8 and SAGA regulate Snf1 AMP kinase activity. Mol Cell Biol 31(15):3126-35, 2011. e-Pub 2011. PMID: 21628526.
- Atanassov BS, Koutelou E, Dent SY. The role of deubiquitinating enzymes in chromatin regulation. FEBS Lett 585(13):2016-23, 2011. e-Pub 2010. PMID: 20974139.
- Koutelou E, Hirsch CL, Dent SY. Multiple faces of the SAGA complex. Curr Opin Cell Biol 22(3):374-82, 2010. e-Pub 2010. PMID: 20363118.
- Koutelou E, Sato S, Tomomori-Sato C, Florens L, Swanson SK, Washburn MP, Kokkinaki M, Conaway RC, Conaway JW, Moschonas NK. Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1. J Biol Chem 283(7):3846-53, 2008. e-Pub 2007. PMID: 18077452.
- Pavlopoulos E, Kokkinaki M, Koutelou E, Mitsiadis TA, Prinos P, Delidakis C, Kilpatrick MW, Tsipouras P, Moschonas NK. Cloning, chromosomal organization and expression analysis of Neurl, the mouse homolog of Drosophila melanogaster neuralized gene. Biochim Biophys Acta 1574(3):375-82, 2002. PMID: 11997106.
Patient Reviews
CV information above last modified August 12, 2024